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679 results on '"BEHRE, HERMANN M."'

1. Frequency, morbidity and equity — the case for increased research on male fertility

Author

Kimmins, Sarah, Anderson, Richard A., Barratt, Christopher L. R., Behre, Hermann M., Catford, Sarah R., De Jonge, Christopher J., Delbes, Geraldine, Eisenberg, Michael L., Garrido, Nicolas, Houston, Brendan J., Jørgensen, Niels, Krausz, Csilla, Lismer, Ariane, McLachlan, Robert I., Minhas, Suks, Moss, Tim, Pacey, Allan, Priskorn, Lærke, Schlatt, Stefan, Trasler, Jacquetta, Trasande, Leonardo, Tüttelmann, Frank, Vazquez-Levin, Mónica Hebe, Veltman, Joris A., Zhang, Feng, and O’Bryan, Moira K.

Published
2024
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2. Assisted Reproduction

Author

De Geyter, Christian, Behre, Hermann M., Nieschlag, Eberhard, editor, Behre, Hermann M., editor, Kliesch, Sabine, editor, and Nieschlag, Susan, editor

Published
2023
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3. Therapy with Testosterone

Author

Nieschlag, Eberhard, Behre, Hermann M., Nieschlag, Eberhard, editor, Behre, Hermann M., editor, Kliesch, Sabine, editor, and Nieschlag, Susan, editor

Published
2023
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4. Immunologically Induced Infertility

Author

Meinhardt, Andreas, Schuppe, Hans-Christian, Behre, Hermann M., Nieschlag, Eberhard, editor, Behre, Hermann M., editor, Kliesch, Sabine, editor, and Nieschlag, Susan, editor

Published
2023
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7. Delayed Puberty in Boys

Author

Rohayem, Julia, Partsch, Carl-Joachim, Nieschlag, Eberhard, Behre, Hermann M., Nieschlag, Eberhard, editor, Behre, Hermann M., editor, Kliesch, Sabine, editor, and Nieschlag, Susan, editor

Published
2023
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8. Varicocele

Author

Nieschlag, Eberhard, Kliesch, Sabine, Behre, Hermann M., Nieschlag, Eberhard, editor, Behre, Hermann M., editor, Kliesch, Sabine, editor, and Nieschlag, Susan, editor

Published
2023
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11. Ultrasound Imaging in Andrology

Author

Lotti, Francesco, Zitzmann, Michael, Behre, Hermann M., Nieschlag, Eberhard, editor, Behre, Hermann M., editor, Kliesch, Sabine, editor, and Nieschlag, Susan, editor

Published
2023
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15. Scope and Goals of Andrology

Author

Nieschlag, Eberhard, Behre, Hermann M., Nieschlag, Eberhard, editor, Behre, Hermann M., editor, Kliesch, Sabine, editor, and Nieschlag, Susan, editor

Published
2023
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17. Immunologisch bedingte Infertilität

Author

Meinhardt, Andreas, Schuppe, Hans-Christian, Behre, Hermann M., Nieschlag, Eberhard, editor, Behre, Hermann M., editor, Kliesch, Sabine, editor, and Nieschlag, Susan, editor

Published
2023
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18. Therapie mit Testosteron

Author

Nieschlag, Eberhard, Behre, Hermann M., Nieschlag, Eberhard, editor, Behre, Hermann M., editor, Kliesch, Sabine, editor, and Nieschlag, Susan, editor

Published
2023
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19. Pubertas tarda beim Jungen

Author

Rohayem, Julia, Partsch, Carl-Joachim, Nieschlag, Eberhard, Behre, Hermann M., Nieschlag, Eberhard, editor, Behre, Hermann M., editor, Kliesch, Sabine, editor, and Nieschlag, Susan, editor

Published
2023
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30. Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivation

Author

Young, Samuel, Schiffer, Christian, Wagner, Alice, Patz, Jannika, Potapenko, Anton, Herrmann, Leonie, Nordhoff, Verena, Pock, Tim, Krallmann, Claudia, Stallmeyer, Birgit, Ropke, Albrecht, Kierzek, Michelina, Biagioni, Cristina, Wang, Tao, Haalck, Lars, Deuster, Dirk, Hansen, Jan N., Wachten, Dagmar, Risse, Benjamin, Behre, Hermann M., Schlatt, Stefan, Kliesch, Sabine, Tuttelmann, Frank, Brenker, Christoph, and Strunker, Timo

Subjects
Infertility, Male -- Risk factors -- Prevention, Fertilization in vitro -- Patient outcomes, Spermatogenesis -- Health aspects, Evidence-based medicine -- Methods, Health care industry
Abstract

The infertility of many couples rests on an enigmatic dysfunction of the man's sperm. To gain insight into the underlying pathomechanisms, we assessed the function of the sperm-specific multisubunit CatSper-channel complex in the sperm of almost 2,300 men undergoing a fertility workup, using a simple motility-based test. We identified a group of men with normal semen parameters but defective CatSper function. These men or couples failed to conceive naturally and upon medically assisted reproduction via intrauterine insemination and in vitro fertilization. Intracytoplasmic sperm injection (ICSI) was, ultimately, required to conceive a child. We revealed that the defective CatSper function was caused by variations in CATSPER genes. Moreover, we unveiled that CatSper-deficient human sperm were unable to undergo hyperactive motility and, therefore, failed to penetrate the egg coat. Thus, our study provides the experimental evidence that sperm hyperactivation is required for human fertilization, explaining the infertility of CatSper-deficient men and the need of ICSI for medically assisted reproduction. Finally, our study also revealed that defective CatSper function and ensuing failure to hyperactivate represents the most common cause of unexplained male infertility known thus far and that this sperm channelopathy can readily be diagnosed, enabling future evidence-based treatment of Affected couples., Introduction Infertility is on the rise, but the underlying causes still remain mostly unknown. In fact, for about a third of infertile men, semen parameters are within reference limits (normozoospermia) [...]

Published
2024
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36. Varikozele

Author

Nieschlag, Eberhard, primary, Kliesch, Sabine, additional, and Behre, Hermann M., additional

Published
2022
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40. Leading at the vanguard of andrology: The Network for Young Researchers in Andrology joins forces with the European Academy of Andrology

Author

de la Iglesia, Alberto, primary, Egeberg, Dorte L., additional, Marcu, Daniel, additional, Richer, Guillaume, additional, Houston, Brendan J., additional, Ammar, Omar, additional, Saritas, Gülizar, additional, Delgouffe, Emily, additional, Jezek, Davor, additional, Krausz, Csilla, additional, Rajpert‐De Meyts, Ewa, additional, and Behre, Hermann M., additional

Published
2024
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42. Frequency, morbidity and equity — the case for increased research on male fertility

Author

Kimmins, Sarah, primary, Anderson, Richard A., additional, Barratt, Christopher L. R., additional, Behre, Hermann M., additional, Catford, Sarah R., additional, De Jonge, Christopher J., additional, Delbes, Geraldine, additional, Eisenberg, Michael L., additional, Garrido, Nicolas, additional, Houston, Brendan J., additional, Jørgensen, Niels, additional, Krausz, Csilla, additional, Lismer, Ariane, additional, McLachlan, Robert I., additional, Minhas, Suks, additional, Moss, Tim, additional, Pacey, Allan, additional, Priskorn, Lærke, additional, Schlatt, Stefan, additional, Trasler, Jacquetta, additional, Trasande, Leonardo, additional, Tüttelmann, Frank, additional, Vazquez-Levin, Mónica Hebe, additional, Veltman, Joris A., additional, Zhang, Feng, additional, and O’Bryan, Moira K., additional

Published
2023
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49. Practice and development of male contraception: European Academy of Andrology and American Society of Andrology guidelines

Author

Wang, Christina, primary, Meriggiola, Maria Cristina, additional, Amory, John K., additional, Barratt, Christopher L. R., additional, Behre, Hermann M., additional, Bremner, William J., additional, Ferlin, Alberto, additional, Honig, Stanton, additional, Kopa, Zsolt, additional, Lo, Kirk, additional, Nieschlag, Eberhard, additional, Page, Stephanie T., additional, Sandlow, Jay, additional, Sitruk‐Ware, Regine, additional, Swerdloff, Ronald S., additional, Wu, Frederick C. W., additional, and Goulis, Dimitrios G., additional

Published
2023
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