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Copyright of GRID - Architecture, Planning & Design Journal is the property of GRID - Architecture, Planning & Design Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Innovation has been highlighted as a magic formula that can solve deep-seated, emerging complex social and economic problems in the public service sector. However, public innovation efforts face both drivers and barriers. Innovation depends on context, and currently different competing governance paradigms' influence has attracted growing academic and political interest regarding the potential of public service innovation. Today, new public governance (NPG) has been suggested as an alternative paradigm to classic public administration (CPA) and new public management (NPM), as the focus of attention has shifted from traditional hierarchical forms of government and market-based competition strategies to interactive- and collaborative-based governance. In this paper, we discuss how elements from different governance paradigms interact, support and undermine one another in terms of innovation in hybrid organisations. Although hybridisation has been described in extant studies on administrative welfare reforms, it barely has been examined in the public innovation literature. This is a theoretical paper based on a scoping review; however, we use the Norwegian Labour and Welfare Administration (NAV) as an illustrative case to explain how hybridisation may lead to both stimulations and perversions regarding the development, implementation and spread of public service innovation. Finally, the paper reflects on how public leaders can handle hybridity within their organisational units. [ABSTRACT FROM AUTHOR]

This study intends to identify existing permeability pathways between post-secondary education and training in Cambodia and to highlight hindrances that hamper the smooth permeability between the two systems. Adopting a hybrid process, the study combines both inductive and deductive thematic analysis approaches in coding transcribed interviews at 15 sampled training institutions and universities. The study finds that the most common route to higher education and training is through the higher qualification programmes under the same track. Although a transfer mechanism between education and training is in place thanks to the establishment of the national qualifications framework and credit transfer system, it is still a much complicated and less utilised pathway. Challenges that thwart the mobility of students include the lack of inter-ministerial collaboration and coordination, issues related to the assessment of students' prior qualifications, and differences in quality assurance mechanisms between the two tracks. Be it more or less, these barriers have contributed to the academisation of technical training and the vocationalisation of higher education in the country. [ABSTRACT FROM AUTHOR]

In its configurative and representational basis, contemporary literature has established a warm dialogue with the classic and modern canons for the formation of literary genres that distance themselves from the poetics in force in order to establish their own aesthetics since the contemporary is in maintaining this gaze fixed on the present by returning to the past to deny or affirm it as the tradition of the new or the new of tradition (PAZ, 2000). The present study is justified in raising the reflection on the form of the epic and the lyric based on the transformations that occurred over the centuries to found an epic-lyric poetry as a renewing style of contemporary Brazilian poetry, the object of this research, which is based on the works Invention of the sea and Os peãs, by Gerardo Mello Mourão. The objective is to demonstrate the resistance of the epic in the current world by the hybrid composition that is established in the act of its production by the exteriority of the real along with the narrator's subjectivity. The problem of intergeneric hybridism is developed through bibliographic and qualitative research with intermediation of the deductive method and through the aesthetic-philosophical bias to demonstrate that it becomes the guiding element of this avant-garde style capable of establishing historical events through the temporality built by the world text. This whole discussion is centered on Aristotle (1992) and Boileau (1990), going through Hegel (1997), Lukacs (2000) and Bakhtin (2010) until arriving at Staiger (1997), Lima (2002), Greenfield (2006) and Kristeva (1995), showing that the epic-lyric poem is supported by the pluridiscursive dialogism maintained between the nature of the stylization of the lyric and epos as a style and not as a novelized process. [ABSTRACT FROM AUTHOR]

I investigate the significance of the forest as a privileged space where Marosa di Giorgio's stories elapse. She establishes the forest as the ideal space for the development of the sinister experiences that dominate her texts. Both the tales and the novel that I study confirm the Freudian definition of the uncanny as that which must have remained hidden but has manifested or, equally disturbing and no less plausible, that which being familiar is presented as strange and alien. To expose such a condition, di Giorgio turns to associations with other arts, especially ló^-century Flemish painting, transforming the forest of her stories into a Garden of Delights in Bosch's style. She also calls for the presence of other artists and, despite her remarkable originality, inscribes herself in a series of Uruguayan authors which produces imaginary spaces for her narrative. [ABSTRACT FROM AUTHOR]

The main aim of the present paper is to use a proof system for hybrid modal logic to formalize what are called false-belief tasks in cognitive psychology, thereby investigating the interplay between cognition and logical reasoning about belief. We consider two different versions of the Smarties task, involving respectively a shift of perspective to another person and to another time. Our formalizations disclose that despite this difference, the two versions of the Smarties task have exactly the same underlying logical structure. We also consider the Sally-Anne task, having a more complicated logical structure, presupposing a 'principle of inertia' saying that a belief is preserved over time, unless there is belief to the contrary. [ABSTRACT FROM AUTHOR]

Background Nonrandom clonal chromosomal aberrations can be detected in approximately 55% of adult patients with acute myeloid leukemia (AML). Recurrent cytogenetic abnormalities play an important role in diagnosis, classification and prognosis of AML. However, several chromosomal abnormalities have not been completely determined or characterized, primarily because of their low incidence and limited amount of data. Results We characterized an AML patient with a novel apparently balanced insertion ins(18;5)(q21;q31.2q35.1) that was cryptic by G-banding. The rearrangement was further examined by molecular cytogenetic methods and oligobased high-resolution array CGH (oaCGH) analysis. We show that an approximately 31.8 Mb large segment from chromosome 5 bands q31.2 to q35.1 has been inserted, by a direct mechanism, into chromosome 18 between bands q12.3 and q21.1. The insertion was unbalanced with concurrent submicroscopic deletions at 5q31.2 (approximately 0.37 Mb in size), 5q35.1q35.2 (approximately 1.98 Mb in size), and 18q12.3q21.1 (approximately 2.07 Mb in size). The microdeletions affect genes on 5q and 18q that have been associated with hematological malignancy and other cancers. A novel juxtaposition of the genes NPM1 and HAUS1 at 5q35.1 and 18q21.1, respectively, was detected by FISH analysis. Searching the literature and the Mitelman database revealed no previously reported ins(18;5) cases. Interestingly, however, two AML patients with translocation t(5;18)(q35;q21) encompassing the 5q35 and 18q21 breakpoint regions as detected in our present ins(18;5) patient have been reported. Conclusions It is well-known that cytogenetic abnormalities on the long arm of chromosome 5 affect hematopoiesis. However, the precise mechanism of their involvement in myeloid transformation is elusive. Our present data shed new light onto the frequent abnormalities on 5q as well as to the less frequent abnormalities observed on 18q in myeloid malignancies. In addition, we show that oaCGH analysis is a useful adjunct to revealing submicroscopic aberrations in regions of clinical importance. Reporting rare and nonrandom chromosomal abnormalities contribute to the identification of the whole spectrum of cytogenetic abnormalities in AML and their prognostic significance. [ABSTRACT FROM AUTHOR]

Copyright of Nueva Revista del Pacífico is the property of Universidad de Playa Ancha de Ciencias de la Educacion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of eHumanista is the property of Professor Antonio Cortijo-Ocana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Abstract: In his article "Monomedial Hybridization in Contemporary Poetry" Jan Baetens argues that the debate on hybridization tends to overemphasize the blurring of boundaries between signs and sign types in all possible forms: combination of types within a given work (multimodal "image-texts," comics and photo-novels, sound poetry, etc.), adaptation and remediation of one sign type by another one (filmic adaptations of novels or novelizations of films, for instance), and, more generally, the simultaneous elaboration of works in various media (the phenomenon that Jenkins called "convergence" or trans-media storytelling). While all these hybridizations have become mainstream today, if we take into account Mitchell's thesis that "there are no visual media" by which he means that "there are no 'pure' media," it becomes possible to draw attention to a more traditional, but perhaps more challenging and disturbing practice of sign usage: the crossing of borders between literary genres and text types, which may involve also the mixture of styles, modes, traditions, audiences and introduce new forms of genre hybridization. [ABSTRACT FROM AUTHOR]

Abstract: A series of novel amide and thioester conjugates between Danshensu and cysteine derivatives have been designed and synthesized based on the strategy of “medicinal chemical hybridization”. Pharmacological evaluation indicated that the amide conjugates 3a/4a/17a and thioester conjugates 6a–d exhibited obvious protective effects on H2O2-induced human umbilical vein endothelial cells (HUVECs). Pretreated with these conjugates could increase glutathione (GSH) activity and decrease malondialdehyde (MDA) level. Further study on mechanism of compound 4a revealed that it was related to its mitochondrial-protective effect and regulation of apoptosis-related proteins expression (Bax, p53, PARP, caspase-3, caspase-9 and Bcl-2). These results indicate that these Danshensu-cysteine analog conjugates possess significant cardiovascular-protective effects and merit further investigation. [Copyright &y& Elsevier]

Using a case study of recent applied theatre work within a secure setting in Auckland, New Zealand, we will consider the ways in which applied theatre can function as a multi-, inter- and trans-disciplinary form — multidisciplinary in that it embraces the various arts disciplines in its makings; inter-disciplinary in that it works with and within other disciplinary sites and, in doing so, is informed by and adapts to those site's discourses and practices; trans-disciplinary in the ways applied theatre practice and research blur traditional disciplinary boundaries to create new approaches and outcomes. Trans-disciplinary work 'leads to the evolution of disciplines, hybridisation and outcomes that are greater than the sum of the parts' (Petts et al., 2008:597). The intention of this paper, therefore, is to present and to untangle some of the tensions and possibilities that reside within prison theatre's complex and many-layered disciplinary relationships. [ABSTRACT FROM AUTHOR]

This article demonstrates that, from 1942 to 1972, the main contributions regarding journalistic-literary connections were expressed in the Gaceta de la Prensa Española, a corporative journal edited by the Francoist Delegación Nacional de Prensa, where journalists, writers and academics interested in reflecting on the news profession collaborated. This paper helps contribute to fill a gap in studies related to connections between Journalism and Literature in Spain. There was very little or nothing published about this hybridization in the journalism writing manuals between the 1940's and 1970's. Consequently these undocumented contributions have been recovered. [ABSTRACT FROM AUTHOR]

In word, deed, and image, Thomas, 3rd Lord Fairfax, parliamentarian Commander-in-Chief during the English Civil Wars, has long been closely associated with the horse. However, there is a hitherto neglected equine link with Fairfax: an unpublished prose work entitled 'A treatise touching the breeding of horses', penned by the General himself in retirement at Nun Appleton. This article argues that Fairfax's treatise asserts a sense of control over the animal kingdom which its author had forfeited in the military and political arena, and explores how it deepens our understanding of the role and status of the horse in early modern England. [ABSTRACT FROM AUTHOR]

Andrei Bodiu discusses some trends detectable in the Romanian literature published in 2011. He discovers that the editorial year 2011 has as a feature a certain type of hybrid books, which mix up memories, fictions and essay from an ethical perspective. One of these remarkable books is the most recent one published by Florin Iaru, an excellent Romanian poet who published a book of, as Andrei Bodiu's argues, « short stories ». Andrei Bodiu debates Iaru's book while integrating it in a famous Romanian literary tradition which starts from 1848 and continues later with the work of Ion Luca Caragiale. [ABSTRACT FROM AUTHOR]