Search

Your search keyword '"Babbini, M."' showing total 214 results
Start Over Author "Babbini, M."
214 results on '"Babbini, M."'

20. Haemolysis due to active venous drainage during cardiopulmonary bypass: comparison of two different techniques.

Author

Cirri, S., Negri, L., Babbini, M., Latis, G., Khlat, B., Tarelli, G., Panisi, P., Mazzaro, E., Bellisario, A., Borghetti, B., Bordignon, F., Ferrara, M., Pavan, H., and Meco, M.

Subjects
HEMOLYSIS & hemolysins, CARDIAC surgery, CENTRIFUGAL pumps, HEMORRHAGE
Abstract

To facilitate mini-access for cardiac surgery, two different methods of active venous drainage are used: vacuum assisted drainage and centrifugal pump aspiration on the venous line. The aim of this study was to compare the haemolysis produced using these two techniques. From June to December 1999, 50 consecutive patients were operated on using a ministernotomy. All of these patients had valvular surgery for either valve repair or valve replacement (9 MVRepair, 11 MVR, 29 AVR, 1 AVR 1 MVR). They were randomized into two groups: Group A, 25 patients who underwent surgery where vacuum assisted drainage was used, and Group B, 25 patients where kinetic asssisted venous drainage with centrifugal pump venous aspiration was used. Patient characteristics of both groups were similar for age, gender, body weight, body surface area, height, cardiopulmonary bypass (CPB) time, aortic crossclamp time, priming volume, cardioplegia volume, haemoglobin concentration, haematocrit, serum creatinine, bilirubin, lactate dehydrogenase (LDH), serum glutamic oxaloacetic transaminase (sGOT), serum glutamic pyruvic transaminase (sGPT), aptoglobin, reticulocytes, and platelet count. We checked all these laboratory parameters preoperatively, at the end of CPB, and 2 and 24h after operation. We also checked haemoglobinuria at these same time points. We assessed blood loss at 6, 12, and 24 h after the operation and calculated total postoperative bleeding. There was a tendency towards a greater increase in LDH, sGOT and sGPT in Group A more than in Group B, but these data did not reach statistical significance. Platelet count was always lower in Group A and aptoglobin increased in Group A more than in Group B. More patients in Group A had haemoglobinuria. These findings indicate that haemolysis is increased more in patients treated with vacuum assisted drainage, when compared to the rise in haemolysis in those treated with centrifugal pump venous drainage. Total bleeding is also greater in Group A. [ABSTRACT FROM AUTHOR]

Published
2001
Full Text
View/download PDF

30. Changes in the liver protein pattern due to lysergic acid diethylamide (LSD)

Author

Babbini M, Missere G, and Tonini G

Subjects
Pharmacology, Chemistry, Liver protein, Proteins, Cell Biology, Cellular and Molecular Neuroscience, Lysergic Acid Diethylamide, Liver metabolism, Biochemistry, Liver, Proteins metabolism, medicine, Molecular Medicine, Molecular Biology, Lysergic acid diethylamide, medicine.drug
Abstract

Mediante elettroforesi in fase libera e stato studiato il protiogramma epatico durante l'intossicazione con dietilamide dell'acido lisergico (LSD) nel ratto albino. Si sono osservate profonde modificazioni del quadro le quali sonto completamente reversibili.

Published
1961

31. Mortality and morbidity from intra-aortic balloon pumps. Risk analysis

Author

Meco, M., Gramegna, G., Yassini, A., Bellisario, A., Mazzaro, E., Babbini, M., Pediglieri, A., Panisi, P., Tarelli, G., Alessandro Frigiola, Menicanti, L., and Cirri, S.

Subjects
Aged, 80 and over, Male, Intra-Aortic Balloon Pumping, Heart Diseases, Incidence, Middle Aged, Risk Assessment, Postoperative Complications, Predictive Value of Tests, Risk Factors, Humans, Female, Vascular Diseases, Cardiac Surgical Procedures, Aged, Retrospective Studies
Abstract

The purpose of this study, was to assess the incidence of and predictors for mortality and morbidity in patients who required postoperative intra-aortic balloon pump (IABP) support.We have retrospectively estimated 116 patients and data were statistically analyzed, and significant variables were evaluated with multivariate analysis.Mortality rate was 57.8% (67 patients). Nineteen patients (16.3%) had major vascular complications: 12 patients (10.3%) limb ischemia, 1 patient (0.9%) aortic dissection, 6 patients (5.2%) mesenteric infarction. Thirty patients (25.8%) had minor vascular complication: 23 patients (19.8%) bleeding from insertion site, 7 (6%) patients infection of insertion site. Limb ischemia was resolved by IABP removal (10 patients), thrombectomy (2 patients). No patient required limb amputation. Sixty patients (51.7%) had renal insufficiency, of which 40 patients needed dialysis. Fifteen patients (10.3%) had neurological complications, 13 patients (11.2%) thrombocytopenia and 5 patients (4.3%) sepsis.The incidence of IABP insertion in our institution was 1.5%. Mortality rate is similar to mortality of other studies in which the IABP has been inserted in the postoperative period. We have found that timing of IABP insertion, thrombocytopenia, presence of peripheral vascular disease and the redo intervention are independent predictors of mortality. We also found that female sex, diabetes, history of cigarette smoking and preoperative use of antiplatelet drugs are independent predictors of limb ischemia. The following factors are instead independent predictors of renal insufficiency: postoperative ejection fraction lower than 40% and non use of dobutamine in the postoperative period.

Catalog

Books, media, physical & digital resources
See catalog results