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3. Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery.

Author

Parisi, Amilcare, Reim, Daniel, Borghi, Felice, Nguyen, Ninh T, Qi, Feng, Coratti, Andrea, Cianchi, Fabio, Cesari, Maurizio, Bazzocchi, Francesca, Alimoglu, Orhan, Gagnière, Johan, Pernazza, Graziano, D'Imporzano, Simone, Zhou, Yan-Bing, Azagra, Juan-Santiago, Facy, Olivier, Brower, Steven T, Jiang, Zhi-Wei, Zang, Lu, Isik, Arda, Gemini, Alessandro, Trastulli, Stefano, Novotny, Alexander, Marano, Alessandra, Liu, Tong, Annecchiarico, Mario, Badii, Benedetta, Arcuri, Giacomo, Avanzolini, Andrea, Leblebici, Metin, Pezet, Denis, Cao, Shou-Gen, Goergen, Martine, Zhang, Shu, Palazzini, Giorgio, D'Andrea, Vito, and Desiderio, Jacopo

Subjects
Humans, Stomach Neoplasms, Postoperative Complications, Laparoscopy, Retrospective Studies, Aged, Aged, 80 and over, Middle Aged, Italy, Female, Male, Robotic Surgical Procedures, Gastrectomy, Gastric cancer, Minimally invasive surgery, Robot-assisted, Robotic, and over, Gastroenterology & Hepatology, Clinical Sciences
Abstract

AimTo investigate the role of minimally invasive surgery for gastric cancer and determine surgical, clinical, and oncological outcomes.MethodsThis is a propensity score-matched case-control study, comparing three treatment arms: robotic gastrectomy (RG), laparoscopic gastrectomy (LG), open gastrectomy (OG). Data collection started after sharing a specific study protocol. Data were recorded through a tailored and protected web-based system. Primary outcomes: harvested lymph nodes, estimated blood loss, hospital stay, complications rate. Among the secondary outcomes, there are: operative time, R0 resections, POD of mobilization, POD of starting liquid diet and soft solid diet. The analysis includes the evaluation of type and grade of postoperative complications. Detailed information of anastomotic leakages is also provided.ResultsThe present analysis was carried out of 1026 gastrectomies. To guarantee homogenous distribution of cases, patients in the RG, LG and OG groups were 1:1:2 matched using a propensity score analysis with a caliper = 0.2. The successful matching resulted in a total sample of 604 patients (RG = 151; LG = 151; OG = 302). The three groups showed no differences in all baseline patients characteristics, type of surgery (P = 0.42) and stage of the disease (P = 0.16). Intraoperative blood loss was significantly lower in the LG (95.93 ± 119.22) and RG (117.91 ± 68.11) groups compared to the OG (127.26 ± 79.50, P = 0.002). The mean number of retrieved lymph nodes was similar between the RG (27.78 ± 11.45), LG (24.58 ± 13.56) and OG (25.82 ± 12.07) approach. A benefit in favor of the minimally invasive approaches was found in the length of hospital stay (P < 0.0001). A similar complications rate was found (P = 0.13). The leakage rate was not different (P = 0.78) between groups.ConclusionLaparoscopic and robotic surgery can be safely performed and proposed as possible alternative to open surgery. The main highlighted benefit is a faster postoperative functional recovery.

Published
2017

7. Robotic, laparoscopic and open surgery for gastric cancer compared on surgical, clinical and oncological outcomes: a multi-institutional chart review. A study protocol of the International study group on Minimally Invasive surgery for GASTRIc Cancer-IMIGASTRIC.

Author

Desiderio, Jacopo, Jiang, Zhi-Wei, Nguyen, Ninh T, Zhang, Shu, Reim, Daniel, Alimoglu, Orhan, Azagra, Juan-Santiago, Yu, Pei-Wu, Coburn, Natalie G, Qi, Feng, Jackson, Patrick G, Zang, Lu, Brower, Steven T, Kurokawa, Yukinori, Facy, Olivier, Tsujimoto, Hironori, Coratti, Andrea, Annecchiarico, Mario, Bazzocchi, Francesca, Avanzolini, Andrea, Gagniere, Johan, Pezet, Denis, Cianchi, Fabio, Badii, Benedetta, Novotny, Alexander, Eren, Tunc, Leblebici, Metin, Goergen, Martine, Zhang, Ben, Zhao, Yong-Liang, Liu, Tong, Al-Refaie, Waddah, Ma, Junjun, Takiguchi, Shuji, Lequeu, Jean-Baptiste, Trastulli, Stefano, and Parisi, Amilcare

Subjects
Humans, Stomach Neoplasms, Laparoscopy, Treatment Outcome, Retrospective Studies, Reproducibility of Results, Robotics, Research Design, Databases, Factual, Female, Male, Minimally Invasive Surgical Procedures, SURGERY, Clinical Sciences, Public Health and Health Services, Other Medical and Health Sciences
Abstract

INTRODUCTION:Gastric cancer represents a great challenge for healthcare providers and requires a multidisciplinary treatment approach in which surgery plays a major role. Minimally invasive surgery has been progressively developed, first with the advent of laparoscopy and recently with the spread of robotic surgery, but a number of issues are currently being debated, including the limitations in performing an effective extended lymph node dissection, the real advantages of robotic systems, the role of laparoscopy for Advanced Gastric Cancer, the reproducibility of a total intracorporeal technique and the oncological results achievable during long-term follow-up. METHODS AND ANALYSIS:A multi-institutional international database will be established to evaluate the role of robotic, laparoscopic and open approaches in gastric cancer, comprising of information regarding surgical, clinical and oncological features. A chart review will be conducted to enter data of participants with gastric cancer, previously treated at the participating institutions. The database is the first of its kind, through an international electronic submission system and a HIPPA protected real time data repository from high volume gastric cancer centres. ETHICS AND DISSEMINATION:This study is conducted in compliance with ethical principles originating from the Helsinki Declaration, within the guidelines of Good Clinical Practice and relevant laws/regulations. A multicentre study with a large number of patients will permit further investigation of the safety and efficacy as well as the long-term outcomes of robotic, laparoscopic and open approaches for the management of gastric cancer. TRIAL REGISTRATION NUMBER:NCT02325453; Pre-results.

Published
2015

8. Predictivity of clinical, laboratory and imaging findings in diagnostic definition of palpable thyroid nodules. A multicenter prospective study

Author

Chiofalo, Maria Grazia, Signoriello, Simona, Fulciniti, Franco, Avenia, Nicola, Ristagno, Serenella, Lombardi, Celestino Pio, Nicolosi, Angelo, Pelizzo, Maria Rosa, Perigli, Giuliano, Polistena, Andrea, Panebianco, Vincenzo, Bellantone, Rocco, Calò, Pietro Giorgio, Boschin, Isabella Merante, Badii, Benedetta, Di Maio, Massimo, Gallo, Ciro, Perrone, Francesco, and Pezzullo, Luciano

Published
2018
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13. Classic and Follicular Variant of Papillary Thyroid Microcarcinoma: 2 Different Phenotypes Beyond Tumor Size

Author

Sparano, Clotilde, primary, Rotondi, Mario, additional, Verdiani, Valentina, additional, Brunori, Paolo, additional, Castiglione, Francesca, additional, Bartoli, Caterina, additional, Perigli, Giuliano, additional, Badii, Benedetta, additional, Vezzosi, Vania, additional, Simontacchi, Gabriele, additional, Livi, Lorenzo, additional, Antonuzzo, Lorenzo, additional, Maggi, Mario, additional, and Petrone, Luisa, additional

Published
2022
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24. L'asile en exil: État des lieux de l'accueil des personnes en demande d'asile à Marseille 2017-2018

Author

Badii, Benedetta, Ben Mahdi, Dominique, Bonis, Margot, Brivio, Federico, Cavalié, Jean-Pierre, Dahdah, Assaf, Dalashy, Magid, Dispa, Lea, Fraïoli, Nathalie, Gasi, Muharem, Maniaval, Elodie, MARSAUD, Gaël, Matrat, Bernadette, Mésini, Béatrice, Natanelic, Denis, Pillant, Laurence, Polo, Mathieu, Rocheteau, Françoise, Vallois, Elise, Viger, Dominique, Non-mixte, Collectif, Philosophes publics, Collectif, CIMADE, Acteurs, Ressources et Territoires dans le Développement (UMR ART-Dev), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Université Paul-Valéry - Montpellier 3 (UPVM)-Université de Perpignan Via Domitia (UPVD)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre de recherches sociologiques et politiques de Paris (CRESPPA), Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Centre National de la Recherche Scientifique (CNRS), Temps, espaces, langages Europe méridionale-Méditerranée (TELEMME), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), ANR-11-IDEX-0001,Amidex,INITIATIVE D'EXCELLENCE AIX MARSEILLE UNIVERSITE(2011), Centre National de la Recherche Scientifique (CNRS)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Université de Montpellier (UM)-Université de Perpignan Via Domitia (UPVD)-Université Paul-Valéry - Montpellier 3 (UPVM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Université Paul-Valéry - Montpellier 3 (UM3)-Université de Perpignan Via Domitia (UPVD)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad), and ANR-11-IDEX-0001-02/10-LABX-0090,LabexMed,LabexMed - Les sciences humaines et sociales au cœur de l'interdisciplinarité pour la Méditerranée(2011)

Subjects
[SHS.DROIT]Humanities and Social Sciences/Law, Asile politique, Accueil des migrants, [SHS.GEO]Humanities and Social Sciences/Geography, [SHS.ANTHRO-SE]Humanities and Social Sciences/Social Anthropology and ethnology, [SHS]Humanities and Social Sciences
Abstract

Comité de Pilotage de l’Observatoire Asile Marseille : La Cimade Sud-Est, l’association Espace de Soutien aux Professionnel.le.s de l’Accueil et du Conseil aux Étranger.ère.s (ESPACE), la Fédération des acteurs de la solidarité PACACorse et le Réseau Hospitalité.; International audience; Un rapport de l'Observatoire Asile MarseilleFruit d'un travail collectif de plus d'un an, ce rapport dresse un état des lieux des conditions d'accueil des personnes en demande d'asile à Marseille. Au centre, les voix de Jamal, Sharon, Joy, Bernadette, Jean et ben d'autres, qui expriment leur ressentis, relatent leur vécu et témoignent des situations rencontrées aujourd'hui dans la cité phocéenne. Le recueil met en évidence les défaillances du dispositif national d'accueil à l'échelle de la ville. Il s'offre comme outil de travail et de réflexion pour les différents acteurs et actrices de l'accueil des exilé.e.s et plaide pour la mise en œuvre d'une politique inconditionnelle d'accueil et d'hospitalité.

Published
2018

25. The Clinical Value of Fluorescent Lymphography with Indocyanine Green During Robotic Surgery for Gastric Cancer: a Matched Cohort Study

Author

Cianchi, Fabio, primary, Indennitate, Giampiero, additional, Paoli, Beatrice, additional, Ortolani, Manuela, additional, Lami, Gabriele, additional, Manetti, Natalia, additional, Tarantino, Ottaviano, additional, Messeri, Sara, additional, Foppa, Caterina, additional, Badii, Benedetta, additional, Novelli, Luca, additional, Skalamera, Ileana, additional, Nelli, Tommaso, additional, Coratti, Francesco, additional, Perigli, Giuliano, additional, and Staderini, Fabio, additional

Published
2019
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27. Lymph node mapping with near-infrared fluorescence imaging during robotic surgery for gastric cancer: a pilot study

Author

Cianchi, Fabio, primary, Indennitate, Giampiero, additional, Trallori, Giacomo, additional, Paoli, Beatrice, additional, Ortolani, Manuela, additional, Taddei, Antonio, additional, Lami, Gabriele, additional, Foppa, Caterina, additional, Badii, Benedetta, additional, Novelli, Luca, additional, Skalamera, Ileana, additional, Montanelli, Paolo, additional, Coratti, Francesco, additional, Perigli, Giuliano, additional, and Staderini, Fabio, additional

Published
2018
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29. Robotic vs laparoscopic distal gastrectomy with D2 lymphadenectomy for gastric cancer: a retrospective comparative mono-institutional study

Author

Cianchi, Fabio, primary, Indennitate, Giampiero, additional, Trallori, Giacomo, additional, Ortolani, Manuela, additional, Paoli, Beatrice, additional, Macrì, Giuseppe, additional, Lami, Gabriele, additional, Mallardi, Beatrice, additional, Badii, Benedetta, additional, Staderini, Fabio, additional, Qirici, Etleva, additional, Taddei, Antonio, additional, Ringressi, Maria Novella, additional, Messerini, Luca, additional, Novelli, Luca, additional, Bagnoli, Siro, additional, Bonanomi, Andrea, additional, Foppa, Caterina, additional, Skalamera, Ileana, additional, Fiorenza, Giulia, additional, and Perigli, Giuliano, additional

Published
2016
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31. Robotic rectal surgery: State of the art

Author

Staderini, Fabio, primary, Foppa, Caterina, additional, Minuzzo, Alessio, additional, Badii, Benedetta, additional, Qirici, Etleva, additional, Trallori, Giacomo, additional, Mallardi, Beatrice, additional, Lami, Gabriele, additional, Macrì, Giuseppe, additional, Bonanomi, Andrea, additional, Bagnoli, Siro, additional, Perigli, Giuliano, additional, and Cianchi, Fabio, additional

Published
2016
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32. Survival after laparoscopic and open surgery for colon cancer: a comparative, single-institution study

Author

Cianchi, Fabio, primary, Trallori, Giacomo, additional, Mallardi, Beatrice, additional, Macrì, Giuseppe, additional, Biagini, Maria Rosa, additional, Lami, Gabriele, additional, Indennitate, Giampiero, additional, Bagnoli, Siro, additional, Bonanomi, Andrea, additional, Messerini, Luca, additional, Badii, Benedetta, additional, Staderini, Fabio, additional, Skalamera, Ileana, additional, Fiorenza, Giulia, additional, and Perigli, Giuliano, additional

Published
2015
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35. Totally Laparoscopic Versus Open Gastrectomy for Gastric Cancer: A Matched Cohort Study

Author

Cianchi, Fabio, primary, Qirici, Etleva, additional, Trallori, Giacomo, additional, Macrì, Giuseppe, additional, Indennitate, Giampiero, additional, Ortolani, Manuela, additional, Paoli, Beatrice, additional, Biagini, Maria Rosa, additional, Galli, Andrea, additional, Messerini, Luca, additional, Mallardi, Beatrice, additional, Badii, Benedetta, additional, Staderini, Fabio, additional, and Perigli, Giuliano, additional

Published
2013
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37. Adequacy of Lymphadenectomy in Laparoscopic Colorectal Cancer Surgery

Author

Cianchi, Fabio, primary, Cortesini, Camillo, additional, Trallori, Giacomo, additional, Messerini, Luca, additional, Novelli, Luca, additional, Comin, Camilla Eva, additional, Qirici, Etleva, additional, Bonanomi, Andrea, additional, Macrì, Giuseppe, additional, Badii, Benedetta, additional, Kokomani, Aurora, additional, and Perigli, Giuliano, additional

Published
2012
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39. Classic and follicular variant of papillary thyroid microcarcinoma: 2 different phenotypes beyond tumor size

Author

Sparano, Clotilde, Rotondi, Mario, Verdiani, Valentina, Brunori, Paolo, Castiglione, Francesca, Bartoli, Caterina, Perigli, Giuliano, Badii, Benedetta, Vezzosi, Vania, Simontacchi, Gabriele, Livi, Lorenzo, Antonuzzo, Lorenzo, Maggi, Mario, Petrone, Luisa, Sparano, Clotilde, Rotondi, Mario, Verdiani, Valentina, Brunori, Paolo, Castiglione, Francesca, Bartoli, Caterina, Perigli, Giuliano, Badii, Benedetta, Vezzosi, Vania, Simontacchi, Gabriele, Livi, Lorenzo, Antonuzzo, Lorenzo, Maggi, Mario, and Petrone, Luisa

Abstract

Context: Despite the wide revision of current guidelines, the management of papillary thyroid microcarcinoma (mPTC) still has to be decided case by case. There is conflicting evidence about the role of more frequent histological subtypes, and no data about potential differences at presentation. Objective: Our aim was to compare the phenotype of the 2 most frequent mPTC variants, namely, classical papillary thyroid microcarcinoma (mPTCc) and the follicular variant of papillary thyroid microcarcinoma (mFVPTC). Methods: Retrospective observational study, from January 2008 to December 2017 of a consecutive series of patients with mPTCc and mFVPTC. All cases were classified according to the 2015 American Thyroid Association (ATA) risk classification. Clinical and preclinical features of mPTCc and mFVPTC at diagnosis were collected. The comparison was also performed according to the incidental/nonincidental diagnosis and differences were verified by binary logistic analysis. Results: In total, 235 patients were eligible for the analysis (125 and 110 mPTCc and mFVPTC, respectively). Compared with mPTCc, mFVPTCs were more often incidental and significantly smaller (4 vs 7mm) (P <. 001 all), possibly influenced by the higher rate of incidental detection. mFVPTC and incidental (P <. 001 both) tumors were significantly more often allocated within the low-risk class. A logistic regression model, with ATA risk class as the dependent variable, showed that both mFVPTC (OR 0.465 [0.235-0.922]; P =. 028]) and incidental diagnosis (OR 0.074 [0.036-0.163]; P <. 001) independently predicted ATA risk stratification. Conclusion: mFVPTC shows some differences in diagnostic presentation compared with mPTCc, and seems to retain a significant number of favorable features, including a prevalent onset as incidental diagnosis.

40. Single-incision laparoscopic colorectal surgery for cancer: state of art.

Author

Cianchi F, Staderini F, and Badii B

Subjects
Clinical Trials as Topic, Colectomy, Humans, Medical Oncology methods, Medical Oncology trends, Natural Orifice Endoscopic Surgery, Neoplasms surgery, Treatment Outcome, Umbilicus surgery, Colorectal Neoplasms surgery, Digestive System Surgical Procedures, Laparoscopy methods
Abstract

A number of clinical trials have demonstrated that the laparoscopic approach for colorectal cancer resection provides the same oncologic results as open surgery along with all clinical benefits of minimally invasive surgery. During the last years, a great effort has been made to research for minimizing parietal trauma, yet for cosmetic reasons and in order to further reduce surgery-related pain and morbidity. New techniques, such as natural orifice transluminal endoscopic surgery (NOTES) and single-incision laparoscopy (SIL) have been developed in order to reach the goal of "scarless" surgery. Although NOTES may seem not fully suitable or safe for advanced procedures, such as colectomies, SIL is currently regarded as the next major advance in the progress of minimally invasive surgical approaches to colorectal disease that is more feasible in generalized use. The small incision through the umbilicus allows surgeons to use familiar standard laparoscopic instruments and thus, perform even complex procedures which require extraction of large surgical specimens or intestinal anastomosis. The cosmetic result from SIL is also better because the only incision is made through the umbilicus which can hide the wound effectively after operation. However, SIL raises a number of specific new challenges compared with the laparoscopic conventional approach. A reduced capacity for triangulation, the repeated conflicts between the shafts of the instruments and the difficulties to achieve a correct exposure of the operative field are the most claimed issues. The use therefore of this new approach for complex colorectal procedures might understandingly be viewed as difficult to implement, especially for oncologic cases.

Published
2014
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