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15 results on '"Bahavar, Atefeh"'

3. Association of viral infection with bladder cancer: A systematic review and meta-analysis

Author

Motlaghzadeh, Saeed, Tabatabaei, Farbod, Eshragh, Fatemeh, Tavakoli, Ahmad, Mobasheri, Nafise, Kiani, Seyed Jalal, Saadati, Hassan, Asli, Samira, Chegeni, Ardalan Maleki, Letafati, Arash, Khatami, Alireza, Hosseini, Mahdiyeh, Salavatiha, Zahra, Babaei, Abouzar, Fakheri Sueini, Venus, Asadi, Dorna, Keyvanlou, Zahra, Maskouni, Elham Jafari, Bahavar, Atefeh, Sorouri Majd, Mahdieh, Esfandiari, Amir Hossein, Khazaee, Hasti, Soleymani, Parastoo, Shahamiri, Kamal, Moazamiyanfar, Reza, Shirazi, Sepideh Bourenjan, Hafezi, Arya, Zarei, Mohammad, Khalesi, Zohreh, and Ghorbani, Saied

Published
2024
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6. Association between human Epstein–Barr virus and brain cancer: a systematic review and meta-analysis

Author

Ghorbani, Saied, primary, Tambrchi, Vahid, additional, Farzi, Rana, additional, Khatami, Alireza, additional, Samiei, Rahil Nahid, additional, Saadati, Hassan, additional, Noori, Maryam, additional, Letafati, Arash, additional, Bahavar, Atefeh, additional, Hezarpishe, Noorin, additional, Musavioun, Mehrshid, additional, Mirzaei, Bahareh, additional, Meftagh, Mohadeseh Sadat, additional, Doust, Najme Khodaei, additional, Hejami, Fatemeh, additional, and Kiani, Seyed Jalal, additional

Published
2023
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7. Global epidemiology of HBV infection among hemodialysis patients: A systematic review and meta-analysis

Author

Khalesi, Zohreh, primary, Razizadeh, Mohammad Hossein, additional, Javadi, Mahsa, additional, Bahavar, Atefeh, additional, Keyvanlou, Zahra, additional, Saadati, Hassan, additional, Letafati, Arash, additional, Khatami, Alireza, additional, Kachooei, Atefeh, additional, Khales, Pegah, additional, Alborzi, Ehsan, additional, Hosseini, Mahdiyeh, additional, Tambrchi, Vahid, additional, Jafari Maskouni, Elham, additional, Taheri, Nafiseh, additional, Zafarani, Alireza, additional, Motlaghzadeh, Saeed, additional, Dehghani, Hamid, additional, Shalpoush, Nadia, additional, Masoudi, Alireza, additional, Noorafaz, Marzieh, additional, Habib, Zahra, additional, Zarei, Mohammad, additional, Kiani, Seyed Jalal, additional, and Ghorbani, Saied, additional

Published
2023
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10. Association between human herpesviruses and multiple sclerosis: A systematic review and meta-analysis

Author

Khalesi, Zohreh, primary, Tamrchi, Vahid, additional, Razizadeh, Mohammad Hossein, additional, Letafati, Arash, additional, Moradi, Pouya, additional, Habibi, Arezoo, additional, Habibi, Negar, additional, Heidari, Jafar, additional, Noori, Maryam, additional, Nahid Samiei, Mahboubeh, additional, Azarash, Ziba, additional, Hoseini, Mahdiyeh, additional, Saadati, Hassan, additional, Bahavar, Atefeh, additional, Farajzade, Maryam, additional, Saeb, Sepideh, additional, Hadadi, Mohammad, additional, Sorouri Majd, Mahdieh, additional, Mothlaghzadeh, Saeed, additional, Fazli, Paria, additional, Asgari, Katayoon, additional, Kiani, Seyed Jalal, additional, and Ghorbani, Saied, additional

Published
2023
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13. Investigating the effect of MAP2K1 gene (MEK1) in MAPK pathway in the induction of adult T-cell leukemia/lymphoma (ATLL).

Author

Hosseini, Parastoo, Foroushani, Abbas Rahimi, Marjani, Arezoo, Tavakoli, Mahnaz, Amiri, Abdollah, Hosseini, Amin, Bahavar, Atefeh, Mozhgani, Sayed-Hamidreza, and Norouzi, Mehdi

Subjects
ADULT T-cell leukemia, GENE expression, MITOGEN-activated protein kinases, RAS proteins, HTLV-I
Abstract

Background and Objectives: HTLV-1 is responsible for two important diseases, HAM/TSP and ATLL. Approximately 10 to 20 million people are infected with HTLV-1 worldwide. Identifying altered genes in different cancers is crucial for finding potential treatment strategies. One of the proteins of the RAS/MAPK signaling pathway is MEK1, which is made from the MAP2K1 gene. The effects of the MAP2K1 gene on the MAPK signaling pathway are not yet fully elucidated. The current study aims to determine the MAP2K1 gene mutations and the level of MAP2K1 gene expression in ATLL patients compared to healthy individuals. Materials and Methods: Ten ATLL and 10 healthy control individuals were investigated in this study. We used ELISA test to screen anti-HTLV-I antibodies and PCR for confirmation of infection. Then, we extracted total RNA from fresh whole blood, and cDNA was synthesized. The expression levels of the MAP2K1 gene were examined by qRT-PCR, and to check possible mutations in the MAP2K1 gene; all samples were sequenced and analyzed by BioEdite Software. Results: MAP2K1 gene expression in the ATLL group was significantly higher than in the healthy control (P=0.001). The mutational sequencing analysis showed nucleotide 212 (SR) change and identification mutations at different nucleotides that were entirely different from the nucleotide mutations defined in the UniProt database. Conclusion: These results could be a perspective in the prevention, prognosis, and targeted treatment of diseases in which the MAP2K1 gene plays a vital role. [ABSTRACT FROM AUTHOR]

Published
2023

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