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Based on the Fick’s law, model about the migration of silver-loaded zeolite on antibacterial kraft paper was built, and migration of antibacterial agent in distilled water, 65 % ethanol and 4 % acetic acid at 2 h、24 h、96 h、240 h、480h、720h and 960 h under 40 °C were detected by AAS. The predicted and experimental results were compared using MATLAB software. The results are shown that the turns of migration in different foodstuff are that 65 % ethanol>4 % acetic acid>distilled water, while silver ion is not detected in olive oil and N-hexane. The migration in distilled water, 65 % ethanol and 4 % acetic acid can be well fitted with the predicted model, and the migration in 4 % acetic acid is similar with the model’s result in certain period of time, and migration of antibacterial agent from papers to food stimulants in different effective migration coefficient, depth of paper and time can be greatly predicted with.