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9 results on '"Baibakov Galina"'

1. A novel technique for quantifying changes in vascular density, endothelial cell proliferation and protein expression in response to modulators of angiogenesis using the chick chorioallantoic membrane (CAM) assay

Author

Kohn Elise, Knezevic Vladimir, Lorang Dominique, Baibakov Galina, Vu Huan, He Mei, O'Connor Sarah, Patton Angela, Kayton Mark L, Miller Walter J, Alexander H Richard, Stirling David, Payvandi Faribourz, Muller George W, and Libutti Steven K

Subjects
Angiogenesis, Chorioallantoic membrane (CAM), Confocal microscopy, XTT assay, Layered Expression Scanning (LES), Medicine
Abstract

Abstract Reliable quantitative evaluation of molecular pathways is critical for both drug discovery and treatment monitoring. We have modified the CAM assay to quantitatively measure vascular density, endothelial proliferation, and changes in protein expression in response to anti-angiogenic and pro-angiogenic agents. This improved CAM assay can correlate changes in vascular density with changes seen on a molecular level. We expect that these described modifications will result in a single in vivo assay system, which will improve the ability to investigate molecular mechanisms underlying the angiogenic response.

Published
2004
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6. Modulation of Tumor-host Interactions, Angiogenesis, and Tumor Growth by Tissue Inhibitor of Metalloproteinase 2 via a Novel Mechanism

Author

Feldman, Andrew L., primary, Stetler-Stevenson, William G., additional, Costouros, Nick G., additional, Knezevic, Vladimir, additional, Baibakov, Galina, additional, Alexander, H. Richard, additional, Lorang, Dominique, additional, Hewitt, Stephen M., additional, Seo, Dong-Wan, additional, Miller, Marshall S., additional, O’Connor, Sarah, additional, and Libutti, Steven K., additional

Published
2004
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7. Layered expression scanning: multiplex analysis of RNA and protein gels

Author

Tangrea, Michael A., primary, Flaig, Michael J., additional, Ramesh, Arun, additional, Best, Carolyn J.M., additional, Baibakov, Galina V., additional, Hewitt, Stephen M., additional, Mitchell, Capre D., additional, Hartmann, Dan-Paul, additional, Knezevic, Vladimir, additional, Emmert-Buck, Michael R., additional, and Chuaqui, Rodrigo F., additional

Published
2003
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8. MEN1 gene mutation analysis of high-grade neuroendocrine lung carcinoma

Author

Debelenko, Larisa V., primary, Swalwell, Jennifer I., additional, Kelley, Michael J., additional, Brambilla, Elisabeth, additional, Manickam, Pachiappan, additional, Baibakov, Galina, additional, Agarwal, Sunita K., additional, Spiegel, Allen M., additional, Marx, Stephen J., additional, Chandrasekharappa, Settara C., additional, Collins, Francis S., additional, Travis, William D., additional, and Emmert-Buck, Michael R., additional

Published
2000
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9. A novel technique for quantifying changes in vascular density, endothelial cell proliferation and protein expression in response to modulators of angiogenesis using the chick chorioallantoic membrane (CAM) assay.

Author

Miller, Walter J., Kayton, Mark L., Patton, Angela, O'Connor, Sarah, Mei He, Huan Vu, Baibakov, Galina, Lorang, Dominique, Knezevic, Vladimir, Kohn, Elise, Alexander, H. Richard, Stirling, David, Payvandi, Faribourz, Muller, George W., and Libutti, Steven K.

Subjects
NEOVASCULARIZATION, GENE expression, CELL proliferation, CELL growth, QUANTITATIVE research
Abstract

Reliable quantitative evaluation of molecular pathways is critical for both drug discovery and treatment monitoring. We have modified the CAM assay to quantitatively measure vascular density, endothelial proliferation, and changes in protein expression in response to anti-angiogenic and pro-angiogenic agents. This improved CAM assay can correlate changes in vascular density with changes seen on a molecular level. We expect that these described modifications will result in a single in vivo assay system, which will improve the ability to investigate molecular mechanisms underlying the angiogenic response. [ABSTRACT FROM AUTHOR]

Published
2004
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