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376 results on '"Balasubramanian, Deepak"'

3. Cholera Dynamics and the Emergence of Pandemic Vibrio cholerae

Author

Balasubramanian, Deepak, López-Pérez, Mario, Almagro-Moreno, Salvador, Crusio, Wim E., Series Editor, Dong, Haidong, Series Editor, Radeke, Heinfried H., Series Editor, Rezaei, Nima, Series Editor, Steinlein, Ortrud, Series Editor, Xiao, Junjie, Series Editor, Almagro-Moreno, Salvador, editor, and Pukatzki, Stefan, editor

Published
2023
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4. Improving accuracy in nodal staging of oral cancer: Proposal of a new system

Author

Subramaniam, Narayana, Heller, Gillian, Clark, Jonathan Robert, Gupta, Ruta, Goldstein, David, de Almeida, John R., Hosni, Ali, Balasubramanian, Deepak, Thankappan, Krishnakumar, Iyer, Subramania, Batstone, Martin, Iyer, N. Gopal, Smee, Robert I., Chandrasekhar, Naveen Hedne, Pillai, Vijay, Shetty, Vivek, Rangappa, Vidyabhushan, Veness, Michael, and Low, Tsu-Hui (Hubert)

Published
2024
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6. Oncological outcomes of compartmental surgery and wide local excision in oral tongue and floor of the mouth cancer

Author

Missale, Francesco, Marchi, Filippo, Iandelli, Andrea, Subramaniam, Narayana, Dokhe, Yogesh, Sampieri, Claudio, Mattavelli, Davide, Bresciani, Lorenzo, Carobbio, Andrea Luigi Camillo, Grammatica, Alberto, Thankappan, Krishnakumar, Iyer, Subramania, Fontanella, Walter, Giannini, Lorenzo, Peretti, Giorgio, Parrinello, Giampiero, Balasubramanian, Deepak, and Piazza, Cesare

Published
2022
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9. Lip Reconstruction

Author

Jani, Khyati, Balasubramanian, Deepak, Thankappan, Krishnakumar, Iyer, Subramania, Bahadur, Sudhir, editor, and Iyer, Subramania, editor

Published
2021
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12. Metrics of pN-staging in oral squamous cell carcinoma: An analysis of 1,905 patients

Author

Mirian, Christian, Gerds, Thomas A., Pedersen, Maria M., de Ridder, Mischa, Balm, Alfons, Mattavelli, Davide, Piazza, Cesare, Jensen, Lasse R., Balasubramanian, Deepak, Subramaniam, Narayana, Dokhe, Yogesh, Thankappan, Krishnakumar, Iyer, Subramania, Karam, Sana D., Wiegand, Susanne, Feeley, Linda, Milross, Chris, Gao, Kan, Palme, Carsten E., Low, Tsu-Hui (Hubert), Gupta, Ruta, Freudlsperger, Christian, Moratin, Julius, Sheahan, Patrick, Clark, Jonathan, and Ovesen, Therese

Published
2021
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16. Geographical heterogeneity in the American Joint committee on Cancer oral cancer staging and prognostic implications

Author

Subramaniam, Narayana, Clark, Jonathan Robert, Goldstein, David, de Almeida, John, Abdalaty, Ali Hosni Ali, Balasubramanian, Deepak, Thankappan, Krishnakumar, Iyer, Subramania, Batstone, Martin, Iyer, N. Gopal, Smee, Robert I, Chandrasekhar, Naveen Hedne, Pillai, Vijay, Shetty, Vivek, Rangappa, Vidyabhushan, Veness, Michael, and Low, Tsu-Hui Hubert

Published
2021
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24. Lip Reconstruction

Author

Jani, Khyati, primary, Balasubramanian, Deepak, additional, Thankappan, Krishnakumar, additional, and Iyer, Subramania, additional

Published
2020
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30. Geographic Inequities in Coverage of Maternal and Child health Services in Haryana State of India

Author

Prinja, Shankar, Balasubramanian, Deepak, Sharma, Atul, Gupta, Rakesh, Rana, Saroj Kumar, and Kumar, Rajesh

Subjects
Statistics, User statistics, Demographic aspects, Maternal health services -- User statistics -- Demographic aspects, Child health services -- User statistics -- Demographic aspects, Medical care utilization -- Statistics, Health care disparities -- Statistics, Medical care -- Utilization
Abstract

Author(s): Shankar Prinja [sup.1] , Deepak Balasubramanian [sup.1] , Atul Sharma [sup.1] , Rakesh Gupta [sup.2] , Saroj Kumar Rana [sup.1] , Rajesh Kumar [sup.1] Author Affiliations: (Aff1) 0000 0004 [...], Introduction India aims to achieve universal health coverage, with a focus on equitable delivery of services. There is significant evidence on extent of inequities by income status, gender and caste. In this paper, we report geographic inequities in coverage of reproductive, maternal and child health (MCH) services in Haryana state of India. Methods Cross-sectional data on utilization of maternal, child health and family planning services were collected from 12,191 women who had delivered a child in the last one year, 10314 women with 12-23 months old child, and 45864 eligible couples across all districts in Haryana state. Service coverage was assessed based on eight indicators - 6 for maternal health, one for child health and one for family planning. Inter- and intra-district inequalities were compared based on four and three indicators respectively. Results Difference in coverage of full ante-natal care, full immunization and contraceptive prevalence rate between districts performing best and worst was found to be 54%, 65% and 63% respectively. More than one-thirds of the sub-centres (SCs) in Panchkula, Ambala, Gurgaon and Mewat districts had their ante-natal care coverage less than 50% of the respective district average. Similarly, a significant proportion of SCs in Mewat, Panipat and Hisar districts had full immunization rate below 50% of the district average. Conclusion Widespread inter- and intra-district inequities in utilization of MCH services exist. A comprehensive geographical targeting to identify poor performing districts, community development blocks and SCs could result in significant equity gains, besides contributing to quick achievement of sustainable development goals.

Published
2019
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39. Contrasting clinical outcomes and socio‐economic impact of young versus elderly‐onset oral squamous cell carcinoma, a novel health economic analysis.

Author

Singh, Manraj, Thankappan, Krishnakumar, Balasubramanian, Deepak, Pillai, Vijay, Shetty, Vivek, Rangappa, Vidyabhushan, Chandrasekhar, Naveen Hedne, Kekatpure, Vikram, Kuriakose, Moni Abraham, Krishnamurthy, Arvind, Mitra, Arun, Pattatheyil, Arun, Jain, Prateek, Iyer, Subramania, Iyer, N. Gopalakrishna, and Subramaniam, Narayana

Subjects
SQUAMOUS cell carcinoma, EARLY death, TREATMENT effectiveness, ECONOMIC impact, OLDER patients
Abstract

Objectives: The incidence of young‐onset oral squamous cell carcinoma (OSCC) is growing, even among non‐smokers/drinkers. The effects of adverse histopathological features on long‐term oncologic outcomes between the young and old are controversial and confounded by significant heterogeneity. Few studies have evaluated the socio‐economic impact of premature mortality from OSCC. Our study seeks to quantify these differences and their economic impact on society. Materials and Methods: Four hundred and seventy‐eight young (<45 years) and 1660 old patients (≥45 years) with OSCC were studied. Logistic regression determined predictors of recurrence and death. Survival analysis was calculated via the Kaplan–Meier method. A separate health economic analysis was conducted for India and Singapore. Years of Potential Productive Life Lost (YPPLL) were estimated with the Human Capital Approach, and premature mortality cost was derived using population‐level data. Results: Adverse histopathological features were seen more frequently in young OSCC: PNI (42.9% vs. 35%, p = 0.002), LVI (22.4% vs. 17.3%, p = 0.013) and ENE (36% vs. 24.5%, p < 0.001). Although 5‐year OS/DSS were similar, the young cohort had received more intensive adjuvant therapy (CCRT 26.9% vs. 16.6%, p < 0.001). Among Singaporean males, the premature mortality cost per death was US $396,528, and per YPPLL was US $45,486. This was US $397,402 and US $38,458 for females. Among Indian males, the premature mortality cost per death was US $30,641, and per YPPLL was US $595. This was US $ 21,038 and US $305 for females. Conclusion: Young‐onset OSCC is an aggressive disease, mitigated by the ability to receive intensive adjuvant treatment. From our loss of productivity analysis, the socio‐economic costs from premature mortality are substantial. Early cancer screening and educational outreach campaigns should be tailored to this cohort. Alongside, more funding should be diverted to genetic research, developing novel biomarkers and improving the efficacy of adjuvant treatment in OSCC. [ABSTRACT FROM AUTHOR]

Published
2024
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44. Bilateral Microvascular Submandibular Gland Transfer with Implantation of Wharton's Duct in Superior Conjunctival Fornix: A Vision-Saving Procedure for Severe Dry Eye Disease

Author

Sharma, Mohit, additional, Radhakrishnan, Anil, additional, Rai, Shravan, additional, Pillai, Gopal S., additional, Balasubramanian, Deepak, additional, Thankappan, Krishnakumar, additional, G., Srilekha Reddy, additional, Jain, Vasundhra, additional, Badam, Abhinandan, additional, Shah, Kannisha, additional, and Rajan, Amritha V., additional

Published
2022
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47. Primary Tumor Staging for Oral Cancer and a Proposed Modification Incorporating Perineural Invasion: An International Multicenter Study.

Author

Na'ara, Shorook, Subramaniam, Narayana, Deganello, Alberto, Shinnawi, Shadi, Billan, Salem, Mattavelli, Davide, Ferrari, Marco, Balasubramanian, Deepak, Thankappan, Krishnakumar, Iyer, Subramania, and Gil, Ziv

Subjects
ORAL cancer, TUMOR classification, SQUAMOUS cell carcinoma, INSPECTION & review, PROGRESSION-free survival, MULTIVARIATE analysis
Abstract

The objective of this study is to determine if the incorporation of perineural invasion (PNI) into the T‐classification would improve the prognostic performance of TNM‐8. An international, multicenter study of 1049 patients with oral cavity squamous cell carcinoma that were treated from 1994 to 2018 is performed. Various classification models are developed within each T‐category and evaluated using the Harrel‐concordance index (C‐index), Akaike‐information criterion (AIC), and visual inspection. Stratification into distinct prognostic categories, with internal validation, is performed using bootstrapping analysis (SPSS and R‐software). Through multivariate analysis, PNI is significantly associated with disease‐specific survival (p < 0.001). PNI integration into the staging system results in a significantly improved model compared with the current T category alone (lower AIC, p < 0.001). The PNI‐integrated model is superior in predicting differential outcomes between T3 and T4 patients. A new model for T‐classification of oral cavity squamous cell carcinoma is proposed, which is based on incorporating PNI into the staging system. These data can be used for future evaluations of the TNM staging system. [ABSTRACT FROM AUTHOR]

Published
2023
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50. Concurrent chemoradiotherapy for head and neck cancers in older patients: Outcomes and their determinants

Author

Srinivasalu, Vijay, Subramaniam, Narayana, Balasubramanian, Deepak, Kumar, Narender, Philip, Arun, Susan, Annu, Pushpaja, K., Nair, Anoop, Thankappan, Krishnakumar, Jose, Wesley, Iyer, Subramania, and Keechilat, Pavithran

Subjects
Care and treatment, Usage, Chemotherapy -- Usage, Head and neck cancer -- Care and treatment, Carboplatin, Cancer research, Radiotherapy, Patient compliance, Carcinoma, Cancer, Squamous cell carcinoma, Type 2 diabetes, Elderly patients, Cancer patients
Published
2019

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