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1. Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain

Author

Nina Rieckmann, Konrad Neumann, Sarah Feger, Paolo Ibes, Adriane Napp, Daniel Preuß, Henryk Dreger, Gudrun Feuchtner, Fabian Plank, Vojtěch Suchánek, Josef Veselka, Thomas Engstrøm, Klaus F. Kofoed, Stephen Schröder, Thomas Zelesny, Matthias Gutberlet, Michael Woinke, Pál Maurovich-Horvat, Béla Merkely, Patrick Donnelly, Peter Ball, Jonathan D. Dodd, Mark Hensey, Bruno Loi, Luca Saba, Marco Francone, Massimo Mancone, Marina Berzina, Andrejs Erglis, Audrone Vaitiekiene, Laura Zajanckauskiene, Tomasz Harań, Malgorzata Ilnicka Suckiel, Rita Faria, Vasco Gama-Ribeiro, Imre Benedek, Ioana Rodean, Filip Adjić, Nada Čemerlić Adjić, José Rodriguez-Palomares, Bruno Garcia del Blanco, Katriona Brooksbank, Damien Collison, Gershan Davis, Erica Thwaite, Juhani Knuuti, Antti Saraste, Cezary Kępka, Mariusz Kruk, Theodora Benedek, Mihaela Ratiu, Aleksandar N. Neskovic, Radosav Vidakovic, Ignacio Diez, Iñigo Lecumberri, Michael Fisher, Balasz Ruzsics, William Hollingworth, Iñaki Gutiérrez-Ibarluzea, Marc Dewey, and Jacqueline Müller-Nordhorn

Subjects
Chest pain, Angina, Coronary artery disease, Computed tomography angiography, Invasive coronary angiography, Health-related quality of life, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

Abstract Background Health-related quality of life (HRQoL) is impaired in patients with stable angina but patients often present with other forms of chest pain. The aim of this study was to compare the pre-diagnostic HRQoL in patients with suspected coronary artery disease (CAD) according to angina type, gender, and presence of obstructive CAD. Methods From the pilot study for the European DISCHARGE trial, we analysed data from 24 sites including 1263 patients (45.9% women, 61.1 ± 11.3 years) who were clinically referred for invasive coronary angiography (ICA; 617 patients) or coronary computed tomography angiography (CTA; 646 patients). Prior to the procedures, patients completed HRQoL questionnaires: the Short Form (SF)-12v2, the EuroQoL (EQ-5D-3 L) and the Hospital Anxiety and Depression Scale. Results Fifty-five percent of ICA and 35% of CTA patients had typical angina, 23 and 33% had atypical angina, 18 and 28% had non-anginal chest discomfort and 5 and 5% had other chest discomfort, respectively. Patients with typical angina had the poorest physical functioning compared to the other angina groups (SF-12 physical component score; 41.2 ± 8.8, 43.3 ± 9.1, 46.2 ± 9.0, 46.4 ± 11.4, respectively, all age and gender-adjusted p

Published
2020
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2. Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain

Author

Bruno Loi, Marc Dewey, Matthias Gutberlet, Sarah Feger, Audrone Vaitiekiene, Iñaki Gutiérrez-Ibarluzea, Gershan Davis, Mariusz Kruk, Michael Woinke, Gudrun Feuchtner, Juhani Knuuti, Mark Hensey, Fabian Plank, Konrad Neumann, Thomas Zelesny, José Rodríguez-Palomares, Pál Maurovich-Horvat, Nina Rieckmann, Tomasz Harań, Vasco Gama-Ribeiro, Rita Faria, Patrick Donnelly, Marco Francone, Paolo Ibes, Thomas Engstrøm, Adriane Napp, Henryk Dreger, Laura Zajanckauskiene, Iñigo Lecumberri, Antti Saraste, Nada Čemerlić Adjić, Aleksandar N. Neskovic, Erica Thwaite, Jacqueline Müller-Nordhorn, William Hollingworth, Andrejs Erglis, Ignacio Diez, Jonathan D. Dodd, Marina Berzina, Bruno García del Blanco, Stephen Schröder, Filip Adjić, Cezary Kępka, Imre Benedek, Theodora Benedek, Massimo Mancone, Malgorzata Ilnicka Suckiel, Katriona Brooksbank, Radosav Vidakovic, Vojtěch Suchánek, Ioana Rodean, Damien Collison, Daniel Preuß, Mihaela Ratiu, Michael J. Fisher, Béla Merkely, Peter Ball, Luca Saba, Balasz Ruzsics, Klaus F. Kofoed, and Josef Veselka

Subjects
Male, Health-related quality of life, invasive coronary angiography, Pilot Projects, sex distribution, 030204 cardiovascular system & hematology, Chest pain, Hospital Anxiety and Depression Scale, Coronary artery disease, Angina, 0302 clinical medicine, Quality of life, Surveys and Questionnaires, middle aged, 030212 general & internal medicine, humans, Computed tomography angiography, medicine.diagnostic_test, angina, chest pain, computed tomography angiography, coronary artery disease, health-related quality of life, aged, angina pectoris, female, male, pilot projects, surveys and questionnaires, quality of life, General Medicine, Middle Aged, lcsh:R858-859.7, Anxiety, Female, medicine.symptom, medicine.medical_specialty, Atypical Angina, Angina Pectoris/classification, lcsh:Computer applications to medicine. Medical informatics, 03 medical and health sciences, Internal medicine, medicine, Humans, cardiovascular diseases, Sex Distribution, Aged, business.industry, Research, Public Health, Environmental and Occupational Health, Invasive coronary angiography, A300, medicine.disease, Quality of Life, Coronary Artery Disease/diagnosis, business
Abstract

Background: Health-related quality of life (HRQoL) is impaired in patients with stable angina but patients often present with other forms of chest pain. The aim of this study was to compare the pre-diagnostic HRQoL in patients with suspected coronary artery disease (CAD) according to angina type, gender, and presence of obstructive CAD.Methods: From the pilot study for the European DISCHARGE trial, we analysed data from 24 sites including 1263 patients (45.9% women, 61.1 ± 11.3 years) who were clinically referred for invasive coronary angiography (ICA; 617 patients) or coronary computed tomography angiography (CTA; 646 patients). Prior to the procedures, patients completed HRQoL questionnaires: the Short Form (SF)-12v2, the EuroQoL (EQ-5D-3 L) and the Hospital Anxiety and Depression Scale.Results: Fifty-five percent of ICA and 35% of CTA patients had typical angina, 23 and 33% had atypical angina, 18 and 28% had non-anginal chest discomfort and 5 and 5% had other chest discomfort, respectively. Patients with typical angina had the poorest physical functioning compared to the other angina groups (SF-12 physical component score; 41.2 ± 8.8, 43.3 ± 9.1, 46.2 ± 9.0, 46.4 ± 11.4, respectively, all age and gender-adjusted p p p Conclusions: Prior to a diagnostic procedure for stable chest pain, HRQoL is associated with chest pain characteristics, but not with obstructive CAD, and is significantly lower in women.Trial registration: Clinicaltrials.gov, NCT02400229.

Published
2020
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4. CT or Invasive Coronary Angiography in Stable Chest Pain

Author

Pál Maurovich-Horvat, 1, Maria Bosserdt, 1, F Kofoed, Klaus, Nina Rieckmann, 1, Theodora Benedek, 1, Patrick Donnelly, 1, José Rodriguez-Palomares, 1, Andrejs Erglis, 1, Cyril Štěchovský, 1, Gintare Šakalyte, 1, Nada Čemerlić Adić, 1, Matthias Gutberlet, 1, D Dodd, Jonathan, Ignacio Diez, 1, Gershan Davis, 1, Elke Zimmermann, 1, Cezary Kępka, 1, Radosav Vidakovic, 1, Marco Francone, 1, Małgorzata Ilnicka-Suckiel, 1, Fabian Plank, 1, Juhani Knuuti, 1, Rita Faria, 1, Stephen Schröder, 1, Colin Berry, 1, Luca Saba, 1, Balazs Ruzsics, 1, Christine Kubiak, 1, Iñaki Gutierrez-Ibarluzea, 1, Kristian Schultz Hansen, 1, Jacqueline Müller-Nordhorn, 1, Bela Merkely, 1, D Knudsen, Andreas, Imre Benedek, 1, Clare Orr, 1, Filipa Xavier Valente, 1, Ligita Zvaigzne, 1, Vojtěch Suchánek, 1, Laura Zajančkauskiene, 1, Filip Adić, 1, Michael Woinke, 1, Mark Hensey, 1, Iñigo Lecumberri, 1, Erica Thwaite, 1, Michael Laule, 1, Mariusz Kruk, 1, N Neskovic, Aleksandar, Massimo Mancone, 1, Donata Kuśmierz, 1, Gudrun Feuchtner, 1, Mikko Pietilä, 1, Vasco Gama Ribeiro, 1, Tanja Drosch, 1, Christian Delles, 1, Gildo Matta, 1, Michael Fisher, 1, Bálint Szilveszter, 1, Linnea Larsen, 1, Mihaela Ratiu, 1, Stephanie Kelly, 1, Bruno Garcia Del Blanco, 1, Ainhoa Rubio, 1, D Drobni, Zsófia, Birgit Jurlander, 1, Ioana Rodean, 1, Susan Regan, 1, Hug Cuéllar Calabria, 1, Melinda Boussoussou, 1, Thomas Engstrøm, 1, Roxana Hodas, 1, E Napp, Adriane, Robert Haase, 1, Sarah Feger, 1, M Serna-Higuita, Lina, Konrad Neumann, 1, Henryk Dreger, 1, Matthias Rief, 1, Viktoria Wieske, 1, Melanie Estrella, 1, Peter Martus, 1, Marc, Dewey, Béla, Merkely, Pál, Maurovich-Horvat, Thomas, Engstroem, Klaus, F. Kofoed, Imre, Benedek, Theodora, Benedek, Patrick, Donnelly, José, F. Rodríguez-Palomares, Bruno Garcia Del Blanco, Andrejs, Erglis, Ligita, Zvaigzne, Vojtěch, Suchánek, Josef, Veselka, Antanas, Jankauskas, Gintare, Šakalyte, Nada Čemerlić Ađić, Oto, Ađić, Matthias, Gutberlet, Michael, Woinke, Jonathan, D. Dodd, Martin, Quinn, Ignacio Díez González, Inigo, Lecumberri, Gershan, K. Davis, Erika, Thwaite, Michael, Laule, Elke, Zimmermann, Henryk, Dreger, Matthias, Rief, Cezary, Kępka, Mariusz, Kruk, Aleksandar, N. Neskovic, Radosav, Vidakovic, Marco Francone, Massimo Mancone, Tomasz, Haran, Malgorzata, Ilnicka-Suckiel, Gudrun, Feuchtner, Guy, Friedrich, Juhani, Knuuti, Mikko, Pietilä, Rita, Faria, Vasco Gama Ribeiro, Stephen, Schröder, Thomas, Zelesny, Christian, Delles, Colin, Berry, Bruno, Loi, Gildo, Matta, Michael, Fisher, Balasz, Ruzsics, Adriane, E. Napp, Maria, Bosserdt, Melanie, Estrella, Jacob, Geleijns, Christine, Kubiak, Corinna, Meier-Windhorst, Rita, Pilger, Iñaki, Gutiérrez-Ibarluzea, Nora, Ibargoyen-Roteta, Itziar, Etxeandia, Gaizka, Benguria-Arrate, Lorea, Galnares-Cordero, Karsten, Vrangbaeck, Hans, Keiding, Kristian Schultz Hansen, Jacqueline, Müller-Nordhorn, Nina, Rieckmann, Peter, Schlattmann, Mihály, Károlyi, Júlia, Karády, Laszló, Gellér, Levente, Molnár, Tamás, Bárány, István, Édes, Dávid, Becker, Száraz Lili Milan Vecsey-Nagy, Borbala, Vattay, Tem, Jørgensen, Knut, Lindvig, Charlotte, Sørum, Helena Domínguez Vall-Lamora, Thomas, Hermann, Charlotte, Kragelund, Thomas Fritz Hansen, Jawdat, Abdulla, Jens Dahlgaard Hove, Kjeld Skødebjerg Kristensen, Leah, Hammond, Albert Roque Pérez, Imanol Otaegui Irurueta, Enzo Javier Alderete, Sebastian, Albornoz, Karlis, Strenge, Marina, Berzina, Iveta, Mintale, Marija, Tokmanceva, Linda, Glazere, Vita, Saripo, Zanda, Krastina, Dace, Sondore, Theodor, Adla, Martin, Horváth, Tadeáš, Butta, Petra, Hajžmanová, Audronė, Vaitiekienė, Gediminas, Jaruševičius, Kristina, Morkūnaitė, Eglė, Montrimavičienė, Laura, Radionovaitė, Milenko, Cankovic, Andrea, Ljubotina, Christian, Krieghoff, Robin, Gohman, Fabian, Juhrich, Patrick, Seitz, Stephen, Keane, Diarmaid, Cadogan, Claire, O. Dowling, Rudaynah, A. Alali, Siobhan, Quinlan, Edel, Meaney, Peter, Doran, Gerald, Kearns, Siobhan, O. Rourke, Sarah, Foley, Joanne, Clarke, Abdi, Abdi, Aine, Hahessy, Brian, Meehan, Michelle, Healy, Sonya, Allen, Colin, P. Cantwell, Niall, Mulvihill, Charles, Mccreery, David, Keane, Ken, Mcdonald, Peter, Quigley, Sadhbh, O. Sullivan, Brian, O. Riordan, Lara, Toerien, John, Irwin, Paddy, Barrett, Dermot, Malone, Abel, Andres, Eva, Amuriza, Arun, Ranjit, Jaroslav, Hasara, Mohammed, Obeidat, Catherine, Toohey, Sandra, Fullalove, Kate, Fenlon, Nicola, Lawler, Anju, Rawat, Francis, Beni, Julie, Ashcroft, Shirley, Cooper, Jeanette, Hawkins, Kate, Hughes, Nicola, Ashall, Doireann, Dickinson, Gemma, Halligan, Julie, Rawcliffe, Dominik, Laskowski, Anna-Maria, Mielke, Laura, Elzenbeck, Daniel, Preuß, Anne, Karas, Anja, Bärrn, Gustavo, Gehling, Florian, Specht, Lisa, Timm, Karl, Stangl, Verena, Stangl, Anna, Brand, Bernhard, Föllmer, Eser, Isler, Federico, Biavati, Mahmoud, Mohamed, Katrin, Stoyanova, Bohdan, Pryplotskyi, Christian, Wald, Steffen, Lukas, Anna, Oleksiak, Vladimir, Jovanovic, Aleksandra, Maksimovic, Milica, Stefanovic, Aleksandra, Zivanic, Andrea Ceccacci, Gianluca De Rubeis, Pambianchi, Giacomo, Paolo Severino, Tomasz, Harań, Natalia, Ilnicka, Katarzyna, Romanowska, Tomasz, Roleder, Christoph, Beyer, Antti, Saraste, Pedro, Teixeira, Mónica, Carvalho, Wilson, Ferreira, Claúdia, Dias, Nuno, Ferreira, Raquel Menezes Fernandes, André Azul Freitas, Pedro Ribeiro Queirós, Lisa Maria Costa Ribeiro Ferraz, Marion, Steindl, Giles, Roditi, Damien, Collison, Laura, Kelly, Katriona, Brooksbank, Andrew, Dougherty, Rosemary, Woodward, Elizabeth, Boyd, Kate, Smith, Michele, Porcu, Maurizio, Porcu, Francesco, Allegra, Vitanio, Palmisano, Stefano, Cossa, Alberto, Boi, Marco, Melis, Riccardo, Cau, and Christine, Denby

Subjects
Angina Pectoris Coronary Angiography Coronary Artery Disease Computed Tomography

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