179 results on '"Ballard, Theresa"'
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2. Oxytocin attenuates phencyclidine hyperactivity and increases social interaction and nucleus accumben dopamine release in rats
3. Animal Paradigms to Assess Cognition with Translation to Humans
4. TRH and cognition : lesion studies and behavioural models
5. A schizophrenia relevant 5-Choice Serial Reaction Time Task for mice assessing broad monitoring, distractibility and impulsivity
6. The subchronic phencyclidine rat model: relevance for the assessment of novel therapeutics for cognitive impairment associated with schizophrenia
7. Animal Paradigms to Assess Cognition with Translation to Humans
8. Mapping the binding pocket of a novel, high-affinity, slow dissociating tachykinin NK3 receptor antagonist: Biochemical and electrophysiological characterization
9. The atypical antipsychotic risperidone reverses the recognition memory deficits induced by post-weaning social isolation in rats
10. RO4938581, a novel cognitive enhancer acting at GABAA α5 subunit-containing receptors
11. Age-dependent cognitive decline and amygdala pathology in α-synuclein transgenic mice
12. The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison
13. Evidence for improved performance in cognitive tasks following selective NR2B NMDA receptor antagonist pre-treatment in the rat
14. Effects of the mGluR2/3 agonist LY354740 on computerized tasks of attention and working memory in marmoset monkeys
15. Cognitive impairment in major depression and the mGlu2 receptor as a therapeutic target
16. The acetylcholinesterase inhibitor, ENA 713 (Exelon), attenuates the working memory impairment induced by scopolamine in an operant DNMTP task in rats
17. Drug targets for cognitive enhancement in neuropsychiatric disorders
18. Preclinical and Clinical Pharmacology of Basmisanil, a Novel Selective GABAA-α5 Receptor Negative Allosteric Modulator
19. Pharmacological characterization of senktide-induced tail whips
20. The effects of serotonin reuptake inhibitors on locomotor activity in gerbils
21. Enhancing effects of nicotine and impairing effects of scopolamine on distinct aspects of performance in computerized attention and working memory tasks in marmoset monkeys
22. Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent
23. Oxytocin attenuates phencyclidine hyperactivity and increases social interaction and nucleus accumben dopamine release in rats
24. Influence of the 5-HT2C receptor antagonist, SB-242084, in tests of anxiety
25. Inhibition of shock-induced foot tapping behaviour in the gerbil by a tachykinin NK 1 receptor antagonist
26. The NMDA Antagonist EAA 494 Does Not Impair Working Memory in an Operant DNMTP Task in Rats
27. Acutely Administered Clozapine Does Not Modify Naloxone-Induced Withdrawal Jumping in Morphine-Dependent Mice
28. Failed trials for central nervous system disorders do not necessarily invalidate preclinical models and drug targets
29. Rational design of novel pyrrolidine derivatives as orally active neurokinin-3 receptor antagonists
30. Discovery of potent, balanced and orally active dual NK1/NK3 receptor ligands
31. Synthesis and characterization of 1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 4. In vivo active potent and selective non-competitive metabotropic glutamate receptor 2/3 antagonists
32. Chronic Metabotropic Glutamate Receptor 5 Inhibition Corrects Local Alterations of Brain Activity and Improves Cognitive Performance in Fragile X Mice
33. The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABA A α5 inverse agonists for the treatment of cognitive dysfunction
34. Imidazo[1,5- a][1,2,4]-triazolo[1,5- d][1,4]benzodiazepines as potent and highly selective GABA A α5 inverse agonists with potential for the treatment of cognitive dysfunction
35. Discovery of the imidazo[1,5- a][1,2,4]-triazolo[1,5- d][1,4]benzodiazepine scaffold as a novel, potent and selective GABA A α5 inverse agonist series
36. Synthesis and characterization of 1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 3. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists
37. Poster #7 CLOZAPINE REVERSES RECOGNITIONMEMORY BUT NOT SOCIAL INTERACTION DEFICITS IN A “DUAL-HIT” RAT MODEL OF SCHIZOPHRENIA
38. Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice
39. Poster #211 THE BEHAVIORAL PROFILE OF TP-10 IN RODENTS AND NON-HUMAN PRIMATES SUPPORTS PDE10A INHIBITION AS A NOVEL TREATMENT APPROACH FOR SCHIZOPHRENIA
40. Tachykinin neurokinin 3 receptor antagonists: a patent review (2005 – 2010)
41. ChemInform Abstract: Synthesis and Characterization of 1,3-Dihydro-benzo[b][1,4]diazepin-2-one Derivatives. Part 4. In vivo Active Potent and Selective Non-competitive Metabotropic Glutamate Receptor 2/3 Antagonists.
42. Synthesis and characterization of 1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: Part 4. In vivo active potent and selective non-competitive metabotropic glutamate receptor 2/3 antagonists
43. CHARACTERIZATION OF RO4583298 AS A HIGHLY POTENT, DUAL ANTAGONIST WITH IN VIVO ACTIVITY AT TACHYKININ NK1 AND NK3 RECEPTORS
44. Phosphorylation of Tau at S422 is enhanced by Aβ in TauPS2APP triple transgenic mice
45. ChemInform Abstract: Imidazo[1,5‐a][1,2,4]‐triazolo[1,5‐d][1,4]benzodiazepines as Potent and Highly Selective GABAA α5 Inverse Agonists with Potential for the Treatment of Cognitive Dysfunction.
46. Discovery of the imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepine scaffold as a novel, potent and selective GABAA α5 inverse agonist series
47. The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABAA α5 inverse agonists for the treatment of cognitive dysfunction
48. Imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepines as potent and highly selective GABAA α5 inverse agonists with potential for the treatment of cognitive dysfunction
49. Hippocampal-dependent spatial memory functions might be lateralized in rats: An approach combining gene expression profiling and reversible inactivation
50. Synthesis and biological evaluation of fenobam analogs as mGlu5 receptor antagonists
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