667 results on '"Banasik, Karina"'
Search Results
2. Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis.
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Ghouse, Jonas, Sveinbjörnsson, Gardar, Vujkovic, Marijana, Seidelin, Anne-Sofie, Gellert-Kristensen, Helene, Ahlberg, Gustav, Tragante, Vinicius, Rand, Søren, Brancale, Joseph, Vilarinho, Silvia, Lundegaard, Pia, Sørensen, Erik, Erikstrup, Christian, Bruun, Mie, Jensen, Bitten, Brunak, Søren, Banasik, Karina, Ullum, Henrik, Verweij, Niek, Lotta, Luca, Baras, Aris, Mirshahi, Tooraj, Carey, David, Kaplan, David, Lynch, Julie, Morgan, Timothy, Schwantes-An, Tae-Hwi, Dochtermann, Daniel, Pyarajan, Saiju, Tsao, Philip, Laisk, Triin, Mägi, Reedik, Kozlitina, Julia, Tybjærg-Hansen, Anne, Jones, David, Knowlton, Kirk, Nadauld, Lincoln, Ferkingstad, Egil, Björnsson, Einar, Ulfarsson, Magnus, Sturluson, Árni, Sulem, Patrick, Pedersen, Ole, Ostrowski, Sisse, Gudbjartsson, Daniel, Stefansson, Kari, Olesen, Morten, Chang, Kyong-Mi, Holm, Hilma, Bundgaard, Henning, and Stender, Stefan
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Humans ,Liver Cirrhosis ,Genome-Wide Association Study ,Genetic Predisposition to Disease ,Liver Neoplasms ,Carcinoma ,Hepatocellular ,Alanine Transaminase ,Polymorphism ,Single Nucleotide ,Male ,Lipase ,Female ,gamma-Glutamyltransferase ,Membrane Proteins ,Cohort Studies ,Case-Control Studies ,Multifactorial Inheritance ,Risk Factors ,Genetic Variation - Abstract
We report a multi-ancestry genome-wide association study on liver cirrhosis and its associated endophenotypes, alanine aminotransferase (ALT) and γ-glutamyl transferase. Using data from 12 cohorts, including 18,265 cases with cirrhosis, 1,782,047 controls, up to 1 million individuals with liver function tests and a validation cohort of 21,689 cases and 617,729 controls, we identify and validate 14 risk associations for cirrhosis. Many variants are located near genes involved in hepatic lipid metabolism. One of these, PNPLA3 p.Ile148Met, interacts with alcohol intake, obesity and diabetes on the risk of cirrhosis and hepatocellular carcinoma (HCC). We develop a polygenic risk score that associates with the progression from cirrhosis to HCC. By focusing on prioritized genes from common variant analyses, we find that rare coding variants in GPAM associate with lower ALT, supporting GPAM as a potential target for therapeutic inhibition. In conclusion, this study provides insights into the genetic underpinnings of cirrhosis.
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- 2024
3. Homozygosity for a stop-gain variant in CCDC201 causes primary ovarian insufficiency
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Oddsson, Asmundur, Steinthorsdottir, Valgerdur, Oskarsson, Gudjon R., Styrkarsdottir, Unnur, Moore, Kristjan H. S., Isberg, Salvor, Halldorsson, Gisli H., Sveinbjornsson, Gardar, Westergaard, David, Nielsen, Henriette Svarre, Fridriksdottir, Run, Jensson, Brynjar O., Arnadottir, Gudny A., Jonsson, Hakon, Sturluson, Arni, Snaebjarnarson, Audunn S., Andreassen, Ole A., Walters, G. Bragi, Nyegaard, Mette, Erikstrup, Christian, Steingrimsdottir, Thora, Lie, Rolv T., Melsted, Pall, Jonsdottir, Ingileif, Halldorsson, Bjarni V., Thorleifsson, Gudmar, Saemundsdottir, Jona, Magnusson, Olafur Th., Banasik, Karina, Sorensen, Erik, Masson, Gisli, Pedersen, Ole Birger, Tryggvadottir, Laufey, Haavik, Jan, Ostrowski, Sisse Rye, Stefansson, Hreinn, Holm, Hilma, Rafnar, Thorunn, Gudbjartsson, Daniel F., Sulem, Patrick, and Stefansson, Kari
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- 2024
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4. Genome-wide association meta-analysis identifies five loci associated with postpartum hemorrhage
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Westergaard, David, Steinthorsdottir, Valgerdur, Stefansdottir, Lilja, Rohde, Palle Duun, Wu, Xiaoping, Geller, Frank, Tyrmi, Jaakko, Havulinna, Aki S., Solé-Navais, Pol, Flatley, Christopher, Ostrowski, Sisse Rye, Pedersen, Ole Birger, Erikstrup, Christian, Sørensen, Erik, Mikkelsen, Christina, Bruun, Mie Topholm, Aagaard Jensen, Bitten, Brodersen, Thorsten, Ullum, Henrik, Magnus, Per, Andreassen, Ole A., Njolstad, Pål R., Kolte, Astrid Marie, Krebs, Lone, Nyegaard, Mette, Hansen, Thomas Folkmann, Feenstra, Bjarke, Daly, Mark, Lindgren, Cecilia M., Thorleifsson, Gudmar, Stefansson, Olafur A., Sveinbjornsson, Gardar, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Banasik, Karina, Jacobsson, Bo, Laisk, Triin, Laivuori, Hannele, Stefansson, Kari, Brunak, Søren, and Nielsen, Henriette Svarre
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- 2024
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5. Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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Winther-Sørensen, Marie, Garcia, Sara L., Bartholdy, Andreas, Ottenheijm, Maud E., Banasik, Karina, Brunak, Søren, Sørensen, Charlotte M., Gluud, Lise Lotte, Knop, Filip K., Holst, Jens J., Rosenkilde, Mette M., Jensen, Majken K., and Wewer Albrechtsen, Nicolai J.
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- 2024
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6. Uncovering the heritable components of multimorbidities and disease trajectories using a nationwide cohort
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Westergaard, David, Jørgensen, Frederik Hytting, Waaben, Jens, Jung, Alexander Wolfgang, Lademann, Mette, Hansen, Thomas Folkmann, Cremers, Jolien, Ostrowski, Sisse Rye, Pedersen, Ole Birger Vesterager, Reguant, Roc, Jørgensen, Isabella Friis, Fitzgerald, Tom, Birney, Ewan, Banasik, Karina, Mortensen, Laust, and Brunak, Søren
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- 2024
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7. Genome-wide association study reveals a locus in ADARB2 for complete freedom from headache in Danish Blood Donors
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Olofsson, Isa Amalie, Kristjansson, Ragnar P., Callesen, Ida, Davidsson, Olafur, Winsvold, Bendik, Hjalgrim, Henrik, Ostrowski, Sisse R., Erikstrup, Christian, Bruun, Mie Topholm, Pedersen, Ole Birger, Burgdorf, Kristoffer S., Banasik, Karina, Sørensen, Erik, Mikkelsen, Christina, Didriksen, Maria, Dinh, Khoa Manh, Mikkelsen, Susan, Brunak, Søren, Ullum, Henrik, Chalmer, Mona Ameri, Olesen, Jes, Kogelman, Lisette J. A., and Hansen, Thomas Folkmann
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- 2024
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8. GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis
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Skuladottir, Astros Th., Stefansdottir, Lilja, Halldorsson, Gisli H., Stefansson, Olafur A., Bjornsdottir, Anna, Jonsson, Palmi, Palmadottir, Vala, Thorgeirsson, Thorgeir E., Walters, G. Bragi, Gisladottir, Rosa S., Bjornsdottir, Gyda, Jonsdottir, Gudrun A., Sulem, Patrick, Gudbjartsson, Daniel F., Knowlton, Kirk U., Jones, David A., Ottas, Aigar, Pedersen, Ole B., Didriksen, Maria, Brunak, Søren, Banasik, Karina, Hansen, Thomas Folkmann, Erikstrup, Christian, Haavik, Jan, Andreassen, Ole A., Rye, David, Igland, Jannicke, Ostrowski, Sisse Rye, Milani, Lili A., Nadauld, Lincoln D., Stefansson, Hreinn, and Stefansson, Kari
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- 2024
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9. Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors
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Kjerulff, Bertram, Dowsett, Joseph, Jacobsen, Rikke Louise, Gladov, Josephine, Larsen, Margit Hørup, Lundgaard, Agnete Troen, Banasik, Karina, Westergaard, David, Mikkelsen, Susan, Dinh, Khoa Manh, Hindhede, Lotte, Kaspersen, Kathrine Agergård, Schwinn, Michael, Juul, Anders, Poulsen, Betina, Lindegaard, Birgitte, Pedersen, Carsten Bøcker, Sabel, Clive Eric, Bundgaard, Henning, Nielsen, Henriette Svarre, Møller, Janne Amstrup, Boldsen, Jens Kjærgaard, Burgdorf, Kristoffer Sølvsten, Kessing, Lars Vedel, Handgaard, Linda Jenny, Thørner, Lise Wegner, Didriksen, Maria, Nyegaard, Mette, Grarup, Niels, Ødum, Niels, Johansson, Pär I., Jennum, Poul, Frikke-Schmidt, Ruth, Berger, Sanne Schou, Brunak, Søren, Jacobsen, Søren, Hansen, Thomas Folkmann, Lundquist, Tine Kirkeskov, Hansen, Torben, Sørensen, Torben Lykke, Sigsgaard, Torben, Nielsen, Kaspar René, Bruun, Mie Topholm, Hjalgrim, Henrik, Ullum, Henrik, Rostgaard, Klaus, Sørensen, Erik, Pedersen, Ole Birger, Ostrowski, Sisse Rye, and Erikstrup, Christian
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- 2024
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10. A genome-wide association study of social trust in 33,882 Danish blood donors
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Sequeros, Celia Burgos, Hansen, Thomas Folkmann, Westergaard, David, Louloudis, Ioannis, Kalamajski, Sebastian, Röder, Timo, Rohde, Palle Duun, Schwinn, Michael, Clemmensen, Line Harder, Didriksen, Maria, Nyegaard, Mette, Hjalgrim, Henrik, Nielsen, Kaspar René, Bruun, Mie Topholm, Ostrowski, Sisse Rye, Erikstrup, Christian, Mikkelsen, Susan, Sørensen, Erik, Pedersen, Ole Birger Vestager, Brunak, Søren, Banasik, Karina, and Giordano, Giuseppe Nicola
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- 2024
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11. Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effect on recombination
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Steinthorsdottir, Valgerdur, Halldorsson, Bjarni V., Jonsson, Hakon, Palsson, Gunnar, Oddsson, Asmundur, Westergaard, David, Arnadottir, Gudny A., Stefansdottir, Lilja, Banasik, Karina, Esplin, M. Sean, Hansen, Thomas Folkmann, Brunak, Søren, Nyegaard, Mette, Ostrowski, Sisse Rye, Pedersen, Ole Birger Vesterager, Erikstrup, Christian, Thorleifsson, Gudmar, Nadauld, Lincoln D., Haraldsson, Asgeir, Steingrimsdottir, Thora, Tryggvadottir, Laufey, Jonsdottir, Ingileif, Gudbjartsson, Daniel F., Hoffmann, Eva R., Sulem, Patrick, Holm, Hilma, Nielsen, Henriette Svarre, and Stefansson, Kari
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- 2024
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12. The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions
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Rahmioglu, Nilufer, Mortlock, Sally, Ghiasi, Marzieh, Møller, Peter L, Stefansdottir, Lilja, Galarneau, Geneviève, Turman, Constance, Danning, Rebecca, Law, Matthew H, Sapkota, Yadav, Christofidou, Paraskevi, Skarp, Sini, Giri, Ayush, Banasik, Karina, Krassowski, Michal, Lepamets, Maarja, Marciniak, Błażej, Nõukas, Margit, Perro, Danielle, Sliz, Eeva, Sobalska-Kwapis, Marta, Thorleifsson, Gudmar, Topbas-Selcuki, Nura F, Vitonis, Allison, Westergaard, David, Arnadottir, Ragnheidur, Burgdorf, Kristoffer S, Campbell, Archie, Cheuk, Cecilia SK, Clementi, Caterina, Cook, James, De Vivo, Immaculata, DiVasta, Amy, Dorien, O, Donoghue, Jacqueline F, Edwards, Todd, Fontanillas, Pierre, Fung, Jenny N, Geirsson, Reynir T, Girling, Jane E, Harkki, Paivi, Harris, Holly R, Healey, Martin, Heikinheimo, Oskari, Holdsworth-Carson, Sarah, Hostettler, Isabel C, Houlden, Henry, Houshdaran, Sahar, Irwin, Juan C, Jarvelin, Marjo-Riitta, Kamatani, Yoichiro, Kennedy, Stephen H, Kepka, Ewa, Kettunen, Johannes, Kubo, Michiaki, Kulig, Bartosz, Kurra, Venla, Laivuori, Hannele, Laufer, Marc R, Lindgren, Cecilia M, MacGregor, Stuart, Mangino, Massimo, Martin, Nicholas G, Matalliotaki, Charoula, Matalliotakis, Michail, Murray, Alison D, Ndungu, Anne, Nezhat, Camran, Olsen, Catherine M, Opoku-Anane, Jessica, Padmanabhan, Sandosh, Paranjpe, Manish, Peters, Maire, Polak, Grzegorz, Porteous, David J, Rabban, Joseph, Rexrode, Kathyrn M, Romanowicz, Hanna, Saare, Merli, Saavalainen, Liisu, Schork, Andrew J, Sen, Sushmita, Shafrir, Amy L, Siewierska-Górska, Anna, Słomka, Marcin, Smith, Blair H, Smolarz, Beata, Szaflik, Tomasz, Szyłło, Krzysztof, Takahashi, Atsushi, Terry, Kathryn L, Tomassetti, Carla, Treloar, Susan A, Vanhie, Arne, Vincent, Katy, Vo, Kim C, Werring, David J, Zeggini, Eleftheria, Zervou, Maria I, and Adachi, Sosuke
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Biological Sciences ,Genetics ,Contraception/Reproduction ,Clinical Research ,Endometriosis ,Prevention ,Pain Research ,Chronic Pain ,Infertility ,2.1 Biological and endogenous factors ,Aetiology ,Female ,Humans ,Genetic Predisposition to Disease ,Genome-Wide Association Study ,Pain ,Comorbidity ,DBDS Genomic Consortium ,FinnGen Study ,FinnGen Endometriosis Taskforce ,Celmatix Research Team ,23andMe Research Team ,Medical and Health Sciences ,Developmental Biology ,Agricultural biotechnology ,Bioinformatics and computational biology - Abstract
Endometriosis is a common condition associated with debilitating pelvic pain and infertility. A genome-wide association study meta-analysis, including 60,674 cases and 701,926 controls of European and East Asian descent, identified 42 genome-wide significant loci comprising 49 distinct association signals. Effect sizes were largest for stage 3/4 disease, driven by ovarian endometriosis. Identified signals explained up to 5.01% of disease variance and regulated expression or methylation of genes in endometrium and blood, many of which were associated with pain perception/maintenance (SRP14/BMF, GDAP1, MLLT10, BSN and NGF). We observed significant genetic correlations between endometriosis and 11 pain conditions, including migraine, back and multisite chronic pain (MCP), as well as inflammatory conditions, including asthma and osteoarthritis. Multitrait genetic analyses identified substantial sharing of variants associated with endometriosis and MCP/migraine. Targeted investigations of genetically regulated mechanisms shared between endometriosis and other pain conditions are needed to aid the development of new treatments and facilitate early symptomatic intervention.
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- 2023
13. Developmental language disorder – heritability and genetic correlations with other disorders affecting language
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Banasik, Karina, Bay, Jakob, Kjærgaard Boldsen, Jens, Brodersen, Thorsten, Brunak, Søren, Demur, Alfonso Buil, Nordahl Christoffersen, Lea Arregui, Didriksen, Maria, Dinh, Khoa Manh, Dowsett, Joseph, Erikstrup, Christian, Feenstra, Bjarke, Geller, Frank, Gudbjartsson, Daniel, Hansen, Thomas Folkmann, Mikkelsen, Dorte Helenius, Hindhede, Lotte, Hjalgrim, Henrik, von Stemann, Jakob Hjorth, Jensen, Bitten Aagaard, Schork, Andrew Joseph, Kaspersen, Kathrine, Kjerulff, Bertram Dalskov, Kongstad, Mette, Mikkelsen, Susan, Mikkelsen, Christina, Nissen, Janna, Nyegaard, Mette, Ostrowski, Sisse Rye, Pedersen, Ole Birger, Elgaard Quinn, Liam James, Rafnar, Þórunn, Rohde, Palle Duun, Rostgaard, Klaus, Schwinn, Michael, Sørensen, Erik, Stefansson, Kari, Stefánsson, Hreinn, Thørner, Lise Wegner, Þorsteinsdóttir, Unnur, Bruun, Mie Topholm, Ullum, Henrik, Werge, Thomas, Westergaard, David, Nudel, Ron, Chrsitensen, Rikke Vang, Kalnak, Nelli, Lundberg, Mischa, Christoffersen, Lea Arregui Nordahl, Burgdorf, Kristoffer Sølvsten, Pedersen, Ole Birger Vesterager, Gísladóttir, Rósa S., and Walters, G. Bragi
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- 2024
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14. Impact of CCR5Δ32 on the risk of infection, Staphylococcus aureus carriage, and plasma concentrations of chemokines in Danish blood donors
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Dinh, Khoa Manh, Kaspersen, Kathrine Agergård, Mikkelsen, Susan, Kjerulff, Bertram Dalskov, Boldsen, Jens Kjærgaard, Petersen, Mikkel Steen, Burgdorf, Kristoffer Sølvsten, Sørensen, Erik, Aagaard, Bitten, Forman-Ankjær, Barbara, Bruun, Mie Topholm, Banasik, Karina, Hansen, Thomas Folkmann, Nyegaard, Mette, Rohde, Palle Duun, Brunak, Søren, Hjalgrim, Henrik, Ostrowski, Sisse Rye, Pedersen, Ole Birger, Ullum, Henrik, Erikstrup, Lise Tornvig, and Erikstrup, Christian
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- 2024
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15. Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura
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Bjornsdottir, Gyda, Chalmer, Mona A., Stefansdottir, Lilja, Skuladottir, Astros Th., Einarsson, Gudmundur, Andresdottir, Margret, Beyter, Doruk, Ferkingstad, Egil, Gretarsdottir, Solveig, Halldorsson, Bjarni V., Halldorsson, Gisli H., Helgadottir, Anna, Helgason, Hannes, Hjorleifsson Eldjarn, Grimur, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Jonsdottir, Ingileif, Knowlton, Kirk U., Nadauld, Lincoln D., Lund, Sigrun H., Magnusson, Olafur Th., Melsted, Pall, Moore, Kristjan H. S., Oddsson, Asmundur, Olason, Pall I., Sigurdsson, Asgeir, Stefansson, Olafur A., Saemundsdottir, Jona, Sveinbjornsson, Gardar, Tragante, Vinicius, Unnsteinsdottir, Unnur, Walters, G. Bragi, Zink, Florian, Rødevand, Linn, Andreassen, Ole A., Igland, Jannicke, Lie, Rolv T., Haavik, Jan, Banasik, Karina, Brunak, Søren, Didriksen, Maria, T. Bruun, Mie, Erikstrup, Christian, Kogelman, Lisette J. A., Nielsen, Kaspar R., Sørensen, Erik, Pedersen, Ole B., Ullum, Henrik, Masson, Gisli, Thorsteinsdottir, Unnur, Olesen, Jes, Ludvigsson, Petur, Thorarensen, Olafur, Bjornsdottir, Anna, Sigurdardottir, Gudrun R., Sveinsson, Olafur A., Ostrowski, Sisse R., Holm, Hilma, Gudbjartsson, Daniel F., Thorleifsson, Gudmar, Sulem, Patrick, Stefansson, Hreinn, Thorgeirsson, Thorgeir E., Hansen, Thomas F., and Stefansson, Kari
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- 2023
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16. Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth
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Beaumont, Robin N., Flatley, Christopher, Vaudel, Marc, Wu, Xiaoping, Chen, Jing, Moen, Gunn-Helen, Skotte, Line, Helgeland, Øyvind, Solé-Navais, Pol, Banasik, Karina, Albiñana, Clara, Ronkainen, Justiina, Fadista, João, Stinson, Sara Elizabeth, Trajanoska, Katerina, Wang, Carol A., Westergaard, David, Srinivasan, Sundararajan, Sánchez-Soriano, Carlos, Bilbao, Jose Ramon, Allard, Catherine, Groleau, Marika, Kuulasmaa, Teemu, Leirer, Daniel J., White, Frédérique, Jacques, Pierre-Étienne, Cheng, Haoxiang, Hao, Ke, Andreassen, Ole A., Åsvold, Bjørn Olav, Atalay, Mustafa, Bhatta, Laxmi, Bouchard, Luigi, Brumpton, Ben Michael, Brunak, Søren, Bybjerg-Grauholm, Jonas, Ebbing, Cathrine, Elliott, Paul, Engelbrechtsen, Line, Erikstrup, Christian, Estarlich, Marisa, Franks, Stephen, Gaillard, Romy, Geller, Frank, Grove, Jakob, Hougaard, David M., Kajantie, Eero, Morgen, Camilla S., Nohr, Ellen A., Nyegaard, Mette, Palmer, Colin N. A., Pedersen, Ole Birger, Rivadeneira, Fernando, Sebert, Sylvain, Shields, Beverley M., Stoltenberg, Camilla, Surakka, Ida, Thørner, Lise Wegner, Ullum, Henrik, Vaarasmaki, Marja, Vilhjalmsson, Bjarni J., Willer, Cristen J., Lakka, Timo A., Gybel-Brask, Dorte, Bustamante, Mariona, Hansen, Torben, Pearson, Ewan R., Reynolds, Rebecca M., Ostrowski, Sisse R., Pennell, Craig E., Jaddoe, Vincent W. V., Felix, Janine F., Hattersley, Andrew T., Melbye, Mads, Lawlor, Deborah A., Hveem, Kristian, Werge, Thomas, Nielsen, Henriette Svarre, Magnus, Per, Evans, David M., Jacobsson, Bo, Järvelin, Marjo-Riitta, Zhang, Ge, Hivert, Marie-France, Johansson, Stefan, Freathy, Rachel M., Feenstra, Bjarke, and Njølstad, Pål R.
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- 2023
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17. Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target
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Roychowdhury, Tanmoy, Klarin, Derek, Levin, Michael G., Spin, Joshua M., Rhee, Yae Hyun, Deng, Alicia, Headley, Colwyn A., Tsao, Noah L., Gellatly, Corry, Zuber, Verena, Shen, Fred, Hornsby, Whitney E., Laursen, Ina Holst, Verma, Shefali S., Locke, Adam E., Einarsson, Gudmundur, Thorleifsson, Gudmar, Graham, Sarah E., Dikilitas, Ozan, Pattee, Jack W., Judy, Renae L., Pauls-Verges, Ferran, Nielsen, Jonas B., Wolford, Brooke N., Brumpton, Ben M., Dilmé, Jaume, Peypoch, Olga, Juscafresa, Laura Calsina, Edwards, Todd L., Li, Dadong, Banasik, Karina, Brunak, Søren, Jacobsen, Rikke L., Garcia-Barrio, Minerva T., Zhang, Jifeng, Rasmussen, Lars M., Lee, Regent, Handa, Ashok, Wanhainen, Anders, Mani, Kevin, Lindholt, Jes S., Obel, Lasse M., Strauss, Ewa, Oszkinis, Grzegorz, Nelson, Christopher P., Saxby, Katie L., van Herwaarden, Joost A., van der Laan, Sander W., van Setten, Jessica, Camacho, Mercedes, Davis, Frank M., Wasikowski, Rachael, Tsoi, Lam C., Gudjonsson, Johann E., Eliason, Jonathan L., Coleman, Dawn M., Henke, Peter K., Ganesh, Santhi K., Chen, Y. Eugene, Guan, Weihua, Pankow, James S., Pankratz, Nathan, Pedersen, Ole B., Erikstrup, Christian, Tang, Weihong, Hveem, Kristian, Gudbjartsson, Daniel, Gretarsdottir, Solveig, Thorsteinsdottir, Unnur, Holm, Hilma, Stefansson, Kari, Ferreira, Manuel A., Baras, Aris, Kullo, Iftikhar J., Ritchie, Marylyn D., Christensen, Alex H., Iversen, Kasper K., Eldrup, Nikolaj, Sillesen, Henrik, Ostrowski, Sisse R., Bundgaard, Henning, Ullum, Henrik, Burgess, Stephen, Gill, Dipender, Gallagher, Katherine, Sabater-Lleal, Maria, Surakka, Ida, Jones, Gregory T., Bown, Matthew J., Tsao, Philip S., Willer, Cristen J., and Damrauer, Scott M.
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- 2023
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18. Symptoms of attention deficit hyperactivity disorder are associated with Hidradenitis suppurativa in Danish blood donors
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Lindsø Andersen, Pernille, Villumsen, Bente, Saunte, Ditte Marie Lindhardt, Burgdorf, Kristoffer Sølvsten, Didriksen, Maria, Ostrowski, Sisse Rye, Thørner, Lise Wegner, Erikstrup, Christian, Dinh, Khoa Manh, Nielsen, Kaspar René, Brodersen, Thorsten, Bruun, Mie Topholm, Banasik, Karina, Hansen, Thomas Folkmann, Pedersen, Ole Birger, and Jemec, Gregor Borut
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- 2023
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19. Publisher Correction: Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
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Oddsson, Asmundur, Sulem, Patrick, Sveinbjornsson, Gardar, Arnadottir, Gudny A., Steinthorsdottir, Valgerdur, Halldorsson, Gisli H., Atlason, Bjarni A., Oskarsson, Gudjon R., Helgason, Hannes, Nielsen, Henriette Svarre, Westergaard, David, Karjalainen, Juha M., Katrinardottir, Hildigunnur, Fridriksdottir, Run, Jensson, Brynjar O., Tragante, Vinicius, Ferkingstad, Egil, Jonsson, Hakon, Gudjonsson, Sigurjon A., Beyter, Doruk, Moore, Kristjan H. S., Thordardottir, Helga B., Kristmundsdottir, Snaedis, Stefansson, Olafur A., Rantapää-Dahlqvist, Solbritt, Sonderby, Ida Elken, Didriksen, Maria, Stridh, Pernilla, Haavik, Jan, Tryggvadottir, Laufey, Frei, Oleksandr, Walters, G. Bragi, Kockum, Ingrid, Hjalgrim, Henrik, Olafsdottir, Thorunn A., Selbaek, Geir, Nyegaard, Mette, Erikstrup, Christian, Brodersen, Thorsten, Saevarsdottir, Saedis, Olsson, Tomas, Nielsen, Kaspar Rene, Haraldsson, Asgeir, Bruun, Mie Topholm, Hansen, Thomas Folkmann, Steingrimsdottir, Thora, Jacobsen, Rikke Louise, Lie, Rolv T., Djurovic, Srdjan, Alfredsson, Lars, Lopez de Lapuente Portilla, Aitzkoa, Brunak, Soren, Melsted, Pall, Halldorsson, Bjarni V., Saemundsdottir, Jona, Magnusson, Olafur Th., Padyukov, Leonid, Banasik, Karina, Rafnar, Thorunn, Askling, Johan, Klareskog, Lars, Pedersen, Ole Birger, Masson, Gisli, Havdahl, Alexandra, Nilsson, Bjorn, Andreassen, Ole A., Daly, Mark, Ostrowski, Sisse Rye, Jonsdottir, Ingileif, Stefansson, Hreinn, Holm, Hilma, Helgason, Agnar, Thorsteinsdottir, Unnur, Stefansson, Kari, and Gudbjartsson, Daniel F.
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- 2023
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20. Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
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Oddsson, Asmundur, Sulem, Patrick, Sveinbjornsson, Gardar, Arnadottir, Gudny A., Steinthorsdottir, Valgerdur, Halldorsson, Gisli H., Atlason, Bjarni A., Oskarsson, Gudjon R., Helgason, Hannes, Nielsen, Henriette Svarre, Westergaard, David, Karjalainen, Juha M., Katrinardottir, Hildigunnur, Fridriksdottir, Run, Jensson, Brynjar O., Tragante, Vinicius, Ferkingstad, Egil, Jonsson, Hakon, Gudjonsson, Sigurjon A., Beyter, Doruk, Moore, Kristjan H. S., Thordardottir, Helga B., Kristmundsdottir, Snaedis, Stefansson, Olafur A., Rantapää-Dahlqvist, Solbritt, Sonderby, Ida Elken, Didriksen, Maria, Stridh, Pernilla, Haavik, Jan, Tryggvadottir, Laufey, Frei, Oleksandr, Walters, G. Bragi, Kockum, Ingrid, Hjalgrim, Henrik, Olafsdottir, Thorunn A., Selbaek, Geir, Nyegaard, Mette, Erikstrup, Christian, Brodersen, Thorsten, Saevarsdottir, Saedis, Olsson, Tomas, Nielsen, Kaspar Rene, Haraldsson, Asgeir, Bruun, Mie Topholm, Hansen, Thomas Folkmann, Steingrimsdottir, Thora, Jacobsen, Rikke Louise, Lie, Rolv T., Djurovic, Srdjan, Alfredsson, Lars, Lopez de Lapuente Portilla, Aitzkoa, Brunak, Soren, Melsted, Pall, Halldorsson, Bjarni V., Saemundsdottir, Jona, Magnusson, Olafur Th., Padyukov, Leonid, Banasik, Karina, Rafnar, Thorunn, Askling, Johan, Klareskog, Lars, Pedersen, Ole Birger, Masson, Gisli, Havdahl, Alexandra, Nilsson, Bjorn, Andreassen, Ole A., Daly, Mark, Ostrowski, Sisse Rye, Jonsdottir, Ingileif, Stefansson, Hreinn, Holm, Hilma, Helgason, Agnar, Thorsteinsdottir, Unnur, Stefansson, Kari, and Gudbjartsson, Daniel F.
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- 2023
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21. Identification of biomarkers for glycaemic deterioration in type 2 diabetes
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Slieker, Roderick C., Donnelly, Louise A., Akalestou, Elina, Lopez-Noriega, Livia, Melhem, Rana, Güneş, Ayşim, Abou Azar, Frederic, Efanov, Alexander, Georgiadou, Eleni, Muniangi-Muhitu, Hermine, Sheikh, Mahsa, Giordano, Giuseppe N., Åkerlund, Mikael, Ahlqvist, Emma, Ali, Ashfaq, Banasik, Karina, Brunak, Søren, Barovic, Marko, Bouland, Gerard A., Burdet, Frédéric, Canouil, Mickaël, Dragan, Iulian, Elders, Petra J. M., Fernandez, Celine, Festa, Andreas, Fitipaldi, Hugo, Froguel, Phillippe, Gudmundsdottir, Valborg, Gudnason, Vilmundur, Gerl, Mathias J., van der Heijden, Amber A., Jennings, Lori L., Hansen, Michael K., Kim, Min, Leclerc, Isabelle, Klose, Christian, Kuznetsov, Dmitry, Mansour Aly, Dina, Mehl, Florence, Marek, Diana, Melander, Olle, Niknejad, Anne, Ottosson, Filip, Pavo, Imre, Duffin, Kevin, Syed, Samreen K., Shaw, Janice L., Cabrera, Over, Pullen, Timothy J., Simons, Kai, Solimena, Michele, Suvitaival, Tommi, Wretlind, Asger, Rossing, Peter, Lyssenko, Valeriya, Legido Quigley, Cristina, Groop, Leif, Thorens, Bernard, Franks, Paul W., Lim, Gareth E., Estall, Jennifer, Ibberson, Mark, Beulens, Joline W. J., ’t Hart, Leen M, Pearson, Ewan R., and Rutter, Guy A.
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- 2023
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22. DanMAC5: a browser of aggregated sequence variants from 8,671 whole genome sequenced Danish individuals
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Banasik, Karina, Møller, Peter L., Techlo, Tanya R., Holm, Peter C., Walters, G. Bragi, Ingason, Andrés, Rosengren, Anders, Rohde, Palle D., Kogelman, Lisette J. A., Westergaard, David, Siggaard, Troels, Chmura, Piotr J., Chalmer, Mona A., Magnússon, Ólafur Þ., Þórisson, Guðmundur Á., Stefánsson, Hreinn, Guðbjartsson, Daníel F., Stefánsson, Kári, Olesen, Jes, Winther, Simon, Bøttcher, Morten, Brunak, Søren, Werge, Thomas, Nyegaard, Mette, and Hansen, Thomas F.
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- 2023
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23. Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models
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Allesøe, Rosa Lundbye, Lundgaard, Agnete Troen, Hernández Medina, Ricardo, Aguayo-Orozco, Alejandro, Johansen, Joachim, Nissen, Jakob Nybo, Brorsson, Caroline, Mazzoni, Gianluca, Niu, Lili, Biel, Jorge Hernansanz, Leal Rodríguez, Cristina, Brasas, Valentas, Webel, Henry, Benros, Michael Eriksen, Pedersen, Anders Gorm, Chmura, Piotr Jaroslaw, Jacobsen, Ulrik Plesner, Mari, Andrea, Koivula, Robert, Mahajan, Anubha, Vinuela, Ana, Tajes, Juan Fernandez, Sharma, Sapna, Haid, Mark, Hong, Mun-Gwan, Musholt, Petra B., De Masi, Federico, Vogt, Josef, Pedersen, Helle Krogh, Gudmundsdottir, Valborg, Jones, Angus, Kennedy, Gwen, Bell, Jimmy, Thomas, E. Louise, Frost, Gary, Thomsen, Henrik, Hansen, Elizaveta, Hansen, Tue Haldor, Vestergaard, Henrik, Muilwijk, Mirthe, Blom, Marieke T., ‘t Hart, Leen M., Pattou, Francois, Raverdy, Violeta, Brage, Soren, Kokkola, Tarja, Heggie, Alison, McEvoy, Donna, Mourby, Miranda, Kaye, Jane, Hattersley, Andrew, McDonald, Timothy, Ridderstråle, Martin, Walker, Mark, Forgie, Ian, Giordano, Giuseppe N., Pavo, Imre, Ruetten, Hartmut, Pedersen, Oluf, Hansen, Torben, Dermitzakis, Emmanouil, Franks, Paul W., Schwenk, Jochen M., Adamski, Jerzy, McCarthy, Mark I., Pearson, Ewan, Banasik, Karina, Rasmussen, Simon, and Brunak, Søren
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- 2023
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24. Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism
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Ghouse, Jonas, Tragante, Vinicius, Ahlberg, Gustav, Rand, Søren A., Jespersen, Jakob B., Leinøe, Eva Birgitte, Vissing, Christoffer Rasmus, Trudsø, Linea, Jonsdottir, Ingileif, Banasik, Karina, Brunak, Søren, Ostrowski, Sisse R., Pedersen, Ole B., Sørensen, Erik, Erikstrup, Christian, Bruun, Mie Topholm, Nielsen, Kaspar Rene, Køber, Lars, Christensen, Alex H., Iversen, Kasper, Jones, David, Knowlton, Kirk U., Nadauld, Lincoln, Halldorsson, Gisli H., Ferkingstad, Egil, Olafsson, Isleifur, Gretarsdottir, Solveig, Onundarson, Pall T., Sulem, Patrick, Thorsteinsdottir, Unnur, Thorgeirsson, Gudmundur, Gudbjartsson, Daniel F., Stefansson, Kari, Holm, Hilma, Olesen, Morten Salling, and Bundgaard, Henning
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- 2023
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25. Complex effects of sequence variants on lipid levels and coronary artery disease
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Snaebjarnarson, Audunn S., Helgadottir, Anna, Arnadottir, Gudny A., Ivarsdottir, Erna V., Thorleifsson, Gudmar, Ferkingstad, Egil, Einarsson, Gudmundur, Sveinbjornsson, Gardar, Thorgeirsson, Thorgeir E., Ulfarsson, Magnus O., Halldorsson, Bjarni V., Olafsson, Isleifur, Erikstrup, Christian, Pedersen, Ole B., Nyegaard, Mette, Bruun, Mie T., Ullum, Henrik, Brunak, Søren, Iversen, Kasper Karmark, Christensen, Alex Hoerby, Olesen, Morten S., Ghouse, Jonas, Banasik, Karina, Knowlton, Kirk U., Arnar, David O., Thorgeirsson, Gudmundur, Nadauld, Lincoln, Ostrowski, Sisse Rye, Bundgaard, Henning, Holm, Hilma, Sulem, Patrick, Stefansson, Kari, and Gudbjartsson, Daniel F.
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- 2023
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26. Developmental language disorder – a comprehensive study of more than 46,000 individuals
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Nudel, Ron, Christensen, Rikke Vang, Kalnak, Nelli, Schwinn, Michael, Banasik, Karina, Dinh, Khoa Manh, Erikstrup, Christian, Pedersen, Ole Birger, Burgdorf, Kristoffer Sølvsten, Ullum, Henrik, Ostrowski, Sisse Rye, Hansen, Thomas Folkmann, and Werge, Thomas
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- 2023
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27. Estimating the effect of donor sex on red blood cell transfused patient mortality: A retrospective cohort study using a targeted learning and emulated trials-based approach
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Bruun-Rasmussen, Peter, Andersen, Per Kragh, Banasik, Karina, Brunak, Søren, and Johansson, Pär Ingemar
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- 2022
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28. Intervening on the storage time of RBC units and its effects on adverse recipient outcomes using real-world data
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Bruun-Rasmussen, Peter, Kragh Andersen, Per, Banasik, Karina, Brunak, Søren, and Johansson, Pär Ingemar
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- 2022
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29. Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study
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Magnúsdóttir, Ingibjörg, Lovik, Anikó, Unnarsdóttir, Anna Bára, McCartney, Daniel, Ask, Helga, Kõiv, Kadri, Nordahl Christoffersen, Lea Arregui, Johnson, Sverre Urnes, McIntosh, Andrew, Kähler, Anna K., Campbell, Archie, Hauksdóttir, Arna, Fawns-Ritchie, Chloe, Erikstrup, Christian, Helenius, Dorte, Altschul, Drew, Thordardottir, Edda Bjork, Eyþórsson, Elías, Frans, Emma M., Tómasson, Gunnar, Jónsdóttir, Harpa Lind, Rúnarsdóttir, Harpa, Hjalgrim, Henrik, Harõardóttir, Hrönn, González-Hijón, Juan, Banasik, Karina, Dinh, Khoa Manh, Lu, Li, Milani, Lili, Trogstad, Lill, Didriksen, Maria, Ebrahimi, Omid V., Sullivan, Patrick F., Magnus, Per Minor, Shen, Qing, Nesvåg, Ragnar, Mägi, Reedik, Pálsson, Runólfur, Ostrowski, Sisse Rye, Werge, Thomas, Hoffart, Asle, Porteous, David J, Fang, Fang, Jakobsdóttir, Jóhanna, Lehto, Kelli, Andreassen, Ole A., Pedersen, Ole B.V., Aspelund, Thor, Valdimarsdóttir, Unnur Anna, Christoffersen, Lea Arregui Nordahl, Ebrahimi, Omid V, Andreassen, Ole A, and Pedersen, Ole B V
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- 2022
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30. Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study
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Wesolowska-Andersen, Agata, Brorsson, Caroline A., Bizzotto, Roberto, Mari, Andrea, Tura, Andrea, Koivula, Robert, Mahajan, Anubha, Vinuela, Ana, Tajes, Juan Fernandez, Sharma, Sapna, Haid, Mark, Prehn, Cornelia, Artati, Anna, Hong, Mun-Gwan, Musholt, Petra B., Kurbasic, Azra, De Masi, Federico, Tsirigos, Kostas, Pedersen, Helle Krogh, Gudmundsdottir, Valborg, Thomas, Cecilia Engel, Banasik, Karina, Jennison, Chrisopher, Jones, Angus, Kennedy, Gwen, Bell, Jimmy, Thomas, Louise, Frost, Gary, Thomsen, Henrik, Allin, Kristine, Hansen, Tue Haldor, Vestergaard, Henrik, Hansen, Torben, Rutters, Femke, Elders, Petra, t’Hart, Leen, Bonnefond, Amelie, Canouil, Mickaël, Brage, Soren, Kokkola, Tarja, Heggie, Alison, McEvoy, Donna, Hattersley, Andrew, McDonald, Timothy, Teare, Harriet, Ridderstrale, Martin, Walker, Mark, Forgie, Ian, Giordano, Giuseppe N., Froguel, Philippe, Pavo, Imre, Ruetten, Hartmut, Pedersen, Oluf, Dermitzakis, Emmanouil, Franks, Paul W., Schwenk, Jochen M., Adamski, Jerzy, Pearson, Ewan, McCarthy, Mark I., and Brunak, Søren
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- 2022
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31. Author Correction: Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models
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Allesøe, Rosa Lundbye, Lundgaard, Agnete Troen, Hernández Medina, Ricardo, Aguayo-Orozco, Alejandro, Johansen, Joachim, Nissen, Jakob Nybo, Brorsson, Caroline, Mazzoni, Gianluca, Niu, Lili, Biel, Jorge Hernansanz, Leal Rodríguez, Cristina, Brasas, Valentas, Webel, Henry, Benros, Michael Eriksen, Pedersen, Anders Gorm, Chmura, Piotr Jaroslaw, Jacobsen, Ulrik Plesner, Mari, Andrea, Koivula, Robert, Mahajan, Anubha, Vinuela, Ana, Tajes, Juan Fernandez, Sharma, Sapna, Haid, Mark, Hong, Mun-Gwan, Musholt, Petra B., De Masi, Federico, Vogt, Josef, Pedersen, Helle Krogh, Gudmundsdottir, Valborg, Jones, Angus, Kennedy, Gwen, Bell, Jimmy, Thomas, E. Louise, Frost, Gary, Thomsen, Henrik, Hansen, Elizaveta, Hansen, Tue Haldor, Vestergaard, Henrik, Muilwijk, Mirthe, Blom, Marieke T., ‘t Hart, Leen M., Pattou, Francois, Raverdy, Violeta, Brage, Soren, Kokkola, Tarja, Heggie, Alison, McEvoy, Donna, Mourby, Miranda, Kaye, Jane, Hattersley, Andrew, McDonald, Timothy, Ridderstråle, Martin, Walker, Mark, Forgie, Ian, Giordano, Giuseppe N., Pavo, Imre, Ruetten, Hartmut, Pedersen, Oluf, Hansen, Torben, Dermitzakis, Emmanouil, Franks, Paul W., Schwenk, Jochen M., Adamski, Jerzy, McCarthy, Mark I., Pearson, Ewan, Banasik, Karina, Rasmussen, Simon, and Brunak, Søren
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- 2023
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32. Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles
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Hautakangas, Heidi, Winsvold, Bendik S., Ruotsalainen, Sanni E., Bjornsdottir, Gyda, Harder, Aster V. E., Kogelman, Lisette J. A., Thomas, Laurent F., Noordam, Raymond, Benner, Christian, Gormley, Padhraig, Artto, Ville, Banasik, Karina, Bjornsdottir, Anna, Boomsma, Dorret I., Brumpton, Ben M., Burgdorf, Kristoffer Sølvsten, Buring, Julie E., Chalmer, Mona Ameri, de Boer, Irene, Dichgans, Martin, Erikstrup, Christian, Färkkilä, Markus, Garbrielsen, Maiken Elvestad, Ghanbari, Mohsen, Hagen, Knut, Häppölä, Paavo, Hottenga, Jouke-Jan, Hrafnsdottir, Maria G., Hveem, Kristian, Johnsen, Marianne Bakke, Kähönen, Mika, Kristoffersen, Espen S., Kurth, Tobias, Lehtimäki, Terho, Lighart, Lannie, Magnusson, Sigurdur H., Malik, Rainer, Pedersen, Ole Birger, Pelzer, Nadine, Penninx, Brenda W. J. H., Ran, Caroline, Ridker, Paul M., Rosendaal, Frits R., Sigurdardottir, Gudrun R., Skogholt, Anne Heidi, Sveinsson, Olafur A., Thorgeirsson, Thorgeir E., Ullum, Henrik, Vijfhuizen, Lisanne S., Widén, Elisabeth, van Dijk, Ko Willems, Aromaa, Arpo, Belin, Andrea Carmine, Freilinger, Tobias, Ikram, M. Arfan, Järvelin, Marjo-Riitta, Raitakari, Olli T., Terwindt, Gisela M., Kallela, Mikko, Wessman, Maija, Olesen, Jes, Chasman, Daniel I., Nyholt, Dale R., Stefánsson, Hreinn, Stefansson, Kari, van den Maagdenberg, Arn M. J. M., Hansen, Thomas Folkmann, Ripatti, Samuli, Zwart, John-Anker, Palotie, Aarno, and Pirinen, Matti
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- 2022
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33. A genome-wide meta-analysis identifies 50 genetic loci associated with carpal tunnel syndrome
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Skuladottir, Astros Th., Bjornsdottir, Gyda, Ferkingstad, Egil, Einarsson, Gudmundur, Stefansdottir, Lilja, Nawaz, Muhammad Sulaman, Oddsson, Asmundur, Olafsdottir, Thorunn A., Saevarsdottir, Saedis, Walters, G. Bragi, Magnusson, Sigurdur H., Bjornsdottir, Anna, Sveinsson, Olafur A., Vikingsson, Arnor, Hansen, Thomas Folkmann, Jacobsen, Rikke Louise, Erikstrup, Christian, Schwinn, Michael, Brunak, Søren, Banasik, Karina, Ostrowski, Sisse Rye, Troelsen, Anders, Henkel, Cecilie, Pedersen, Ole Birger, Jonsdottir, Ingileif, Gudbjartsson, Daniel F., Sulem, Patrick, Thorgeirsson, Thorgeir E., Stefansson, Hreinn, and Stefansson, Kari
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- 2022
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34. Chronic inflammation markers and cytokine-specific autoantibodies in Danish blood donors with restless legs syndrome
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Dowsett, Joseph, Didriksen, Maria, von Stemann, Jakob Hjorth, Larsen, Margit Hørup, Thørner, Lise Wegner, Sørensen, Erik, Erikstrup, Christian, Pedersen, Ole Birger, Hansen, Morten Bagge, Eugen-Olsen, Jesper, Banasik, Karina, and Ostrowski, Sisse Rye
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- 2022
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35. Author Correction: Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology
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Bjornsdottir, Gyda, Stefansdottir, Lilja, Thorleifsson, Gudmar, Sulem, Patrick, Norland, Kristjan, Ferkingstad, Egil, Oddsson, Asmundur, Zink, Florian, Lund, Sigrun H., Nawaz, Muhammad S., Bragi Walters, G., Skuladottir, Astros Th., Gudjonsson, Sigurjon A., Einarsson, Gudmundur, Halldorsson, Gisli H., Bjarnadottir, Valgerdur, Sveinbjornsson, Gardar, Helgadottir, Anna, Styrkarsdottir, Unnur, Gudmundsson, Larus J., Pedersen, Ole B., Hansen, Thomas Folkmann, Werge, Thomas, Banasik, Karina, Troelsen, Anders, Skou, Soren T., Thørner, Lise Wegner, Erikstrup, Christian, Nielsen, Kaspar Rene, Mikkelsen, Susan, Jonsdottir, Ingileif, Bjornsson, Aron, Olafsson, Ingvar H., Ulfarsson, Elfar, Blondal, Josep, Vikingsson, Arnor, Brunak, Soren, Ostrowski, Sisse R., Ullum, Henrik, Thorsteinsdottir, Unnur, Stefansson, Hreinn, Gudbjartsson, Daniel F., Thorgeirsson, Thorgeir E., and Stefansson, Kari
- Published
- 2022
- Full Text
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36. Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology
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Bjornsdottir, Gyda, Stefansdottir, Lilja, Thorleifsson, Gudmar, Sulem, Patrick, Norland, Kristjan, Ferkingstad, Egil, Oddsson, Asmundur, Zink, Florian, Lund, Sigrun H., Nawaz, Muhammad S., Bragi Walters, G., Skuladottir, Astros Th., Gudjonsson, Sigurjon A., Einarsson, Gudmundur, Halldorsson, Gisli H., Bjarnadottir, Valgerdur, Sveinbjornsson, Gardar, Helgadottir, Anna, Styrkarsdottir, Unnur, Gudmundsson, Larus J., Pedersen, Ole B., Hansen, Thomas Folkmann, Werge, Thomas, Banasik, Karina, Troelsen, Anders, Skou, Soren T., Thørner, Lise Wegner, Erikstrup, Christian, Nielsen, Kaspar Rene, Mikkelsen, Susan, Jonsdottir, Ingileif, Bjornsson, Aron, Olafsson, Ingvar H., Ulfarsson, Elfar, Blondal, Josep, Vikingsson, Arnor, Brunak, Soren, Ostrowski, Sisse R., Ullum, Henrik, Thorsteinsdottir, Unnur, Stefansson, Hreinn, Gudbjartsson, Daniel F., Thorgeirsson, Thorgeir E., and Stefansson, Kari
- Published
- 2022
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37. Cross-tissue transcriptome-wide association studies identify susceptibility genes shared between schizophrenia and inflammatory bowel disease
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Uellendahl-Werth, Florian, Maj, Carlo, Borisov, Oleg, Juzenas, Simonas, Wacker, Eike Matthias, Jørgensen, Isabella Friis, Steiert, Tim Alexander, Bej, Saptarshi, Krawitz, Peter, Hoffmann, Per, Schramm, Christoph, Wolkenhauer, Olaf, Banasik, Karina, Brunak, Søren, Schreiber, Stefan, Karlsen, Tom Hemming, Degenhardt, Franziska, Nöthen, Markus, Franke, Andre, Folseraas, Trine, and Ellinghaus, David
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- 2022
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38. Inflammatory and endothelial host responses in community-acquired pneumonia: exploring the relationships with HbA1c, admission plasma glucose, and glycaemic gap—a cross-sectional study
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Dungu, Arnold Matovu, primary, Lundgaard, Agnete Troen, additional, Ryrsø, Camilla Koch, additional, Hegelund, Maria Hein, additional, Jensen, Andreas Vestergaard, additional, Kristensen, Peter Lommer, additional, Krogh-Madsen, Rikke, additional, Faurholt-Jepsen, Daniel, additional, Ostrowski, Sisse Rye, additional, Banasik, Karina, additional, and Lindegaard, Birgitte, additional
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- 2024
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39. Association of Variants Near the Bradykinin Receptor B2 Gene With Angioedema in Patients Taking ACE Inhibitors
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Ghouse, Jonas, Ahlberg, Gustav, Andreasen, Laura, Banasik, Karina, Brunak, Søren, Schwinn, Michael, Larsen, Ina Holst, Petersen, Oscar, Sørensen, Erik, Ullum, Henrik, Rasmussen, Eva Rye, Eriksson, Niclas, Hallberg, Pär, Wadelius, Mia, Bundgaard, Henning, and Olesen, Morten S.
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- 2021
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40. Inflammatory and endothelial host responses in community-acquired pneumonia:exploring the relationships with HbA1c, admission plasma glucose, and glycaemic gap—a cross-sectional study
- Author
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Dungu, Arnold Matovu, Lundgaard, Agnete Troen, Ryrsø, Camilla Koch, Hegelund, Maria Hein, Jensen, Andreas Vestergaard, Kristensen, Peter Lommer, Krogh-Madsen, Rikke, Faurholt-Jepsen, Daniel, Ostrowski, Sisse Rye, Banasik, Karina, Lindegaard, Birgitte, Dungu, Arnold Matovu, Lundgaard, Agnete Troen, Ryrsø, Camilla Koch, Hegelund, Maria Hein, Jensen, Andreas Vestergaard, Kristensen, Peter Lommer, Krogh-Madsen, Rikke, Faurholt-Jepsen, Daniel, Ostrowski, Sisse Rye, Banasik, Karina, and Lindegaard, Birgitte
- Abstract
Introduction: Diabetes is associated with dysregulated immune function and impaired cytokine release, while transient acute hyperglycaemia has been shown to enhance inflammatory cytokine release in preclinical studies. Although diabetes and acute hyperglycaemia are common among patients with community-acquired pneumonia (CAP), the impact of chronic, acute, and acute-on-chronic hyperglycaemia on the host response within this population remains poorly understood. This study investigated whether chronic, acute, and acute-on- chronic hyperglycaemia are associated with distinct mediators of inflammatory, endothelial, and angiogenic host response pathways in patients with CAP. Methods: In a cross-sectional study of 555 patients with CAP, HbA1c, admission plasma (p)-glucose, and the glycaemic gap (admission p-glucose minus HbA1c- derived average p-glucose) were employed as measures of chronic, acute, and acute-on-chronic hyperglycaemia, respectively. Linear regression was used to model the associations between the hyperglycaemia measures and 47 proteins involved in inflammation, endothelial activation, and angiogenesis measured at admission. The models were adjusted for age, sex, CAP severity, pathogen, immunosuppression, comorbidity, and body mass index. Adjustments for multiple testing were performed with a false discovery rate threshold of less than 0.05. Results: The analyses showed that HbA1c levels were positively associated with IL-8, IL-15, IL-17A/F, IL-1RA, sFlt-1, and VEGF-C. Admission plasma glucose was also positively associated with these proteins and GM-CSF. The glycaemic gap was positively associated with IL-8, IL-15, IL-17A/F, IL-2, and VEGF-C. Conclusion: In conclusion, chronic, acute, and acute-on-chronic hyperglycaemia were positively associated with similar host response mediators. Furthermore, acute and acute-on-chronic hyperglycaemia had unique associations with the inflammatory pathways involving GM-CSF and IL-2, respective, Introduction: Diabetes is associated with dysregulated immune function and impaired cytokine release, while transient acute hyperglycaemia has been shown to enhance inflammatory cytokine release in preclinical studies. Although diabetes and acute hyperglycaemia are common among patients with community-acquired pneumonia (CAP), the impact of chronic, acute, and acute-on-chronic hyperglycaemia on the host response within this population remains poorly understood. This study investigated whether chronic, acute, and acute-on- chronic hyperglycaemia are associated with distinct mediators of inflammatory, endothelial, and angiogenic host response pathways in patients with CAP. Methods: In a cross-sectional study of 555 patients with CAP, HbA1c, admission plasma (p)-glucose, and the glycaemic gap (admission p-glucose minus HbA1c- derived average p-glucose) were employed as measures of chronic, acute, and acute-on-chronic hyperglycaemia, respectively. Linear regression was used to model the associations between the hyperglycaemia measures and 47 proteins involved in inflammation, endothelial activation, and angiogenesis measured at admission. The models were adjusted for age, sex, CAP severity, pathogen, immunosuppression, comorbidity, and body mass index. Adjustments for multiple testing were performed with a false discovery rate threshold of less than 0.05. Results: The analyses showed that HbA1c levels were positively associated with IL-8, IL-15, IL-17A/F, IL-1RA, sFlt-1, and VEGF-C. Admission plasma glucose was also positively associated with these proteins and GM-CSF. The glycaemic gap was positively associated with IL-8, IL-15, IL-17A/F, IL-2, and VEGF-C. Conclusion: In conclusion, chronic, acute, and acute-on-chronic hyperglycaemia were positively associated with similar host response mediators. Furthermore, acute and acute-on-chronic hyperglycaemia had unique associations with the inflammatory pathways involving GM-CSF and IL-2, respectively.
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- 2024
41. Clonal hematopoiesis and COVID-19 hospitalization in Danish adults
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Burgos Sequeros, Celia, Tulstrup, Morten, Bliddal, Sofie, Sørensen, Karina Meden, Nissen, Ioanna, Rezahosseini, Omid, Brooks, Patrick Terrence, Feenstra, Bjarke, Gang, Anne Ortved, Geller, Frank, Hald, Annemette, Harboe, Zitta Barrella, Helleberg, Marie, Jespersen, Jakob S., Lebech, Anne Mette, Lindegaard, Birgitte, Mogensen, Trine H., Møller, Maria Elizabeth Engel, Nielsen, Claus Henrik, Niemann, Carsten Utoft, Podlekareva, Daria, Sejdic, Adin, Sørensen, Erik, Teglgaard, Rebecca Svanberg, Tommerup, Niels, Weis, Nina, Brunak, Søren, Pedersen, Ole Birger Vestager, Banasik, Karina, Feldt-Rasmussen, Ulla, Nielsen, Susanne Dam, Ostrowski, Sisse Rye, Grønbæk, Kirsten, Burgos Sequeros, Celia, Tulstrup, Morten, Bliddal, Sofie, Sørensen, Karina Meden, Nissen, Ioanna, Rezahosseini, Omid, Brooks, Patrick Terrence, Feenstra, Bjarke, Gang, Anne Ortved, Geller, Frank, Hald, Annemette, Harboe, Zitta Barrella, Helleberg, Marie, Jespersen, Jakob S., Lebech, Anne Mette, Lindegaard, Birgitte, Mogensen, Trine H., Møller, Maria Elizabeth Engel, Nielsen, Claus Henrik, Niemann, Carsten Utoft, Podlekareva, Daria, Sejdic, Adin, Sørensen, Erik, Teglgaard, Rebecca Svanberg, Tommerup, Niels, Weis, Nina, Brunak, Søren, Pedersen, Ole Birger Vestager, Banasik, Karina, Feldt-Rasmussen, Ulla, Nielsen, Susanne Dam, Ostrowski, Sisse Rye, and Grønbæk, Kirsten
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- 2024
42. Variants at the Interleukin 1 Gene Locus and Pericarditis
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Thorolfsdottir, Rosa B., Jonsdottir, Andrea B., Sveinbjornsson, Gardar, Aegisdottir, Hildur M., Oddsson, Asmundur, Stefansson, Olafur A., Halldorsson, Gisli H., Saevarsdottir, Saedis, Thorleifsson, Gudmar, Stefansdottir, Lilja, Pedersen, Ole B., Sørensen, Erik, Ghouse, Jonas, Raja, Anna Axelsson, Zheng, Chaoqun, Silajdzija, Elvira, Rand, Søren Albertsen, Erikstrup, Christian, Ullum, Henrik, Mikkelsen, Christina, Banasik, Karina, Brunak, Søren, Ivarsdottir, Erna V., Sigurdsson, Asgeir, Beyter, Doruk, Sturluson, Arni, Einarsson, Hafsteinn, Tragante, Vinicius, Helgason, Hannes, Lund, Sigrun H., Halldorsson, Bjarni V., Sigurpalsdottir, Brynja D., Olafsson, Isleifur, Arnar, David O., Thorgeirsson, Gudmundur, Knowlton, Kirk U., Nadauld, Lincoln D., Gretarsdottir, Solveig, Helgadottir, Anna, Ostrowski, Sisse R., Gudbjartssson, Daniel F., Jonsdottir, Ingileif, Bundgaard, Henning, Holm, Hilma, Sulem, Patrick, Stefansson, Kari, Thorolfsdottir, Rosa B., Jonsdottir, Andrea B., Sveinbjornsson, Gardar, Aegisdottir, Hildur M., Oddsson, Asmundur, Stefansson, Olafur A., Halldorsson, Gisli H., Saevarsdottir, Saedis, Thorleifsson, Gudmar, Stefansdottir, Lilja, Pedersen, Ole B., Sørensen, Erik, Ghouse, Jonas, Raja, Anna Axelsson, Zheng, Chaoqun, Silajdzija, Elvira, Rand, Søren Albertsen, Erikstrup, Christian, Ullum, Henrik, Mikkelsen, Christina, Banasik, Karina, Brunak, Søren, Ivarsdottir, Erna V., Sigurdsson, Asgeir, Beyter, Doruk, Sturluson, Arni, Einarsson, Hafsteinn, Tragante, Vinicius, Helgason, Hannes, Lund, Sigrun H., Halldorsson, Bjarni V., Sigurpalsdottir, Brynja D., Olafsson, Isleifur, Arnar, David O., Thorgeirsson, Gudmundur, Knowlton, Kirk U., Nadauld, Lincoln D., Gretarsdottir, Solveig, Helgadottir, Anna, Ostrowski, Sisse R., Gudbjartssson, Daniel F., Jonsdottir, Ingileif, Bundgaard, Henning, Holm, Hilma, Sulem, Patrick, and Stefansson, Kari
- Abstract
Importance: Recurrent pericarditis is a treatment challenge and often a debilitating condition. Drugs inhibiting interleukin 1 cytokines are a promising new treatment option, but their use is based on scarce biological evidence and clinical trials of modest sizes, and the contributions of innate and adaptive immune processes to the pathophysiology are incompletely understood. Objective: To use human genomics, transcriptomics, and proteomics to shed light on the pathogenesis of pericarditis. Design, Setting, and Participants: This was a meta-analysis of genome-wide association studies of pericarditis from 5 countries. Associations were examined between the pericarditis-associated variants and pericarditis subtypes (including recurrent pericarditis) and secondary phenotypes. To explore mechanisms, associations with messenger RNA expression (cis-eQTL), plasma protein levels (pQTL), and CpG methylation of DNA (ASM-QTL) were assessed. Data from Iceland (deCODE genetics, 1983-2020), Denmark (Copenhagen Hospital Biobank/Danish Blood Donor Study, 1977-2022), the UK (UK Biobank, 1953-2021), the US (Intermountain, 1996-2022), and Finland (FinnGen, 1970-2022) were included. Data were analyzed from September 2022 to August 2023. Exposure: Genotype. Main Outcomes and Measures: Pericarditis. Results: In this genome-wide association study of 4894 individuals with pericarditis (mean [SD] age at diagnosis, 51.4 [17.9] years, 2734 [67.6%] male, excluding the FinnGen cohort), associations were identified with 2 independent common intergenic variants at the interleukin 1 locus on chromosome 2q14. The lead variant was rs12992780 (T) (effect allele frequency [EAF], 31%-40%; odds ratio [OR], 0.83; 95% CI, 0.79-0.87; P = 6.67 × 10-16), downstream of IL1B and the secondary variant rs7575402 (A or T) (EAF, 45%-55%; adjusted OR, 0.89; 95% CI, 0.85-0.93; adjusted P = 9.6 × 10-8). The lead variant rs12992780 had a smaller odds ratio for recurrent pericarditis (0.76) tha
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- 2024
43. Finding Ophthalmic Risk and Evaluating the Value of Eye exams and their predictive Reliability (FOREVER)—A cohort study in a Danish high street optician setting:Design and methodology
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Freiberg, Josefine, Rovelt, Jens, Gazzard, Gus, Cour, Morten la, Kolko, Miriam, Torp‐Pedersen, Christian, Benn, Marianne, Brunak, Søren, Tolstrup, Janne, Toft‐Petersen, Anne Pernille, Burgdorf, Kristoffer Sølvsten, Banasik, Karina, Chmura, Piotr Jaroslaw, Thornit, Dorte Nellemann, Foster, Paul, Crabb, David P., Viswanathan, Ananth, Barman, Sarah, Owen, Christopher G., Rudnicka, Alicja R., Freiberg, Josefine, Rovelt, Jens, Gazzard, Gus, Cour, Morten la, Kolko, Miriam, Torp‐Pedersen, Christian, Benn, Marianne, Brunak, Søren, Tolstrup, Janne, Toft‐Petersen, Anne Pernille, Burgdorf, Kristoffer Sølvsten, Banasik, Karina, Chmura, Piotr Jaroslaw, Thornit, Dorte Nellemann, Foster, Paul, Crabb, David P., Viswanathan, Ananth, Barman, Sarah, Owen, Christopher G., and Rudnicka, Alicja R.
- Abstract
Purpose The purpose of the study was to describe the rationale and design of Project FOREVER (Finding Ophthalmic Risk and Evaluating the Value of Eye exams and their predictive Reliability). Design Project FOREVER will build a comprehensive database of clinical eye and vision data collected from ~280 000 adults at 100 optician stores across Denmark. The FOREVER database (FOREVERdb) includes detailed data from refraction, visual acuity, intraocular pressure, corneal thickness, visual field assessments and retinal fundus images. Linkage to the comprehensive Danish national registries with, that is diagnostic and prescribing data permits investigation of rare associations and risk factors. 30 000 individuals over 50 also provide a saliva sample for later genetic studies and blood pressure measurements. Of these 30 000, 10 000 will also get optical coherence tomography (OCT) nerve and retinal scans. This subpopulation data is reviewed by ophthalmologists for disease detection. All participants will be asked to complete a questionnaire assessing lifestyle, self-perceived eye health and general health. Enrolment of participants began in April 2022. Perspective The FOREVERdb is a powerful tool to answer a wide range of research questions that can pave the way for better eye health. This database will provide valuable insights for future studies investigating the correlations between eye and general health in a Danish population cohort, enabling research to identify potential risk factors for a range of diseases.
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- 2024
44. Multi‐omics analysis reveals drivers of loss of β‐cell function after newly diagnosed autoimmune type 1 diabetes: An INNODIA multicenter study.
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Armenteros, Jose Juan Almagro, Brorsson, Caroline, Johansen, Christian Holm, Banasik, Karina, Mazzoni, Gianluca, Moulder, Robert, Hirvonen, Karoliina, Suomi, Tomi, Rasool, Omid, Bruggraber, Sylvaine F. A., Marcovecchio, M. Loredana, Hendricks, Emile, Al‐Sari, Naba, Mattila, Ismo, Legido‐Quigley, Cristina, Suvitaival, Tommi, Chmura, Piotr J., Knip, Mikael, Schulte, Anke M., and Lee, Jeong Heon
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TYPE 1 diabetes ,MULTIOMICS ,G protein coupled receptors ,KILLER cells ,GENETIC translation ,AUTOIMMUNE diseases - Abstract
Aims: Heterogeneity in the rate of β‐cell loss in newly diagnosed type 1 diabetes patients is poorly understood and creates a barrier to designing and interpreting disease‐modifying clinical trials. Integrative analyses of baseline multi‐omics data obtained after the diagnosis of type 1 diabetes may provide mechanistic insight into the diverse rates of disease progression after type 1 diabetes diagnosis. Methods: We collected samples in a pan‐European consortium that enabled the concerted analysis of five different omics modalities in data from 97 newly diagnosed patients. In this study, we used Multi‐Omics Factor Analysis to identify molecular signatures correlating with post‐diagnosis decline in β‐cell mass measured as fasting C‐peptide. Results: Two molecular signatures were significantly correlated with fasting C‐peptide levels. One signature showed a correlation to neutrophil degranulation, cytokine signalling, lymphoid and non‐lymphoid cell interactions and G‐protein coupled receptor signalling events that were inversely associated with a rapid decline in β‐cell function. The second signature was related to translation and viral infection was inversely associated with change in β‐cell function. In addition, the immunomics data revealed a Natural Killer cell signature associated with rapid β‐cell decline. Conclusions: Features that differ between individuals with slow and rapid decline in β‐cell mass could be valuable in staging and prediction of the rate of disease progression and thus enable smarter (shorter and smaller) trial designs for disease modifying therapies as well as offering biomarkers of therapeutic effect. [ABSTRACT FROM AUTHOR]
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- 2024
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45. Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis
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Hindy, George, Tyrrell, Daniel J., Vasbinder, Alexi, Wei, Changli, Presswalla, Feriel, Wang, Hui, Blakely, Pennelope, Ozel, Ayse Bilge, Graham, Sarah, Holton, Grace H., Dowsett, Joseph, Fahed, Akl C., Amadi, Kingsley-Michael, Erne, Grace K., Tekmulla, Annika, Ismail, Anis, Launius, Christopher, Sotoodehnia, Nona, Pankow, James S., Thorner, Lise Wegner, Erikstrup, Christian, Pedersen, Ole Birger, Banasik, Karina, Brunak, Soren, Ullum, Henrik, Eugen-Olsen, Jesper, Ostrowski, Sisse Rye, Haas, Mary E., Nielsen, Jonas B., Lotta, Luca A., Engstrom, Gunnar, Melander, Olle, Orho-Melander, Marju, Zhao, Lili, Murthy, Venkatesh L., Pinsky, David J., Willer, Cristen J., Heckbert, Susan R., Reiser, Jochen, Goldstein, Daniel R., Desch, Karl C., and Hayek, Salim S.
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Immune response -- Genetic aspects ,Cell receptors -- Health aspects ,Atherosclerosis -- Genetic aspects -- Development and progression -- Care and treatment ,Health care industry - Abstract
People with kidney disease are disproportionately affected by atherosclerosis for unclear reasons. Soluble urokinase plasminogen activator receptor (suPAR) is an immune-derived mediator of kidney disease, levels of which are strongly associated with cardiovascular outcomes. We assessed suPAR's pathogenic involvement in atherosclerosis using epidemiologic, genetic, and experimental approaches. We found serum suPAR levels to be predictive of coronary artery calcification and cardiovascular events in 5,406 participants without known coronary disease. In a genome-wide association meta-analysis including over 25,000 individuals, we identified a missense variant in the plasminogen activator, urokinase receptor (PLAUR) gene (rs4760), confirmed experimentally to lead to higher suPAR levels. Mendelian randomization analysis in the UK Biobank using rs4760 indicated a causal association between genetically predicted suPAR levels and atherosclerotic phenotypes. In an experimental model of atherosclerosis, proprotein convertase subtilisin/kexin-9 (Pcsk9) transfection in mice overexpressing suPAR ([suPAR.sup.Tg]) led to substantially increased atherosclerotic plaques with necrotic cores and macrophage infiltration compared with those in WT mice, despite similar cholesterol levels. Prior to induction of atherosclerosis, aortas of [suPAR.sup.Tg] mice excreted higher levels of CCL2 and had higher monocyte counts compared with WT aortas. Aortic and circulating [suPAR.sup.Tg] monocytes exhibited a proinflammatory profile and enhanced chemotaxis. These findings characterize suPAR as a pathogenic factor for atherosclerosis acting at least partially through modulation of monocyte function., Introduction People with chronic kidney disease (CKD) are disproportionately affected by cardiovascular disease (CVD), with two-thirds of patients having at least one form of CVD, atherosclerosis being the most common [...]
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- 2022
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46. A meta-analysis uncovers the first sequence variant conferring risk of Bell’s palsy
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Skuladottir, Astros Th., Bjornsdottir, Gyda, Thorleifsson, Gudmar, Walters, G. Bragi, Nawaz, Muhammad Sulaman, Moore, Kristjan Helgi Swerford, Olason, Pall I., Thorgeirsson, Thorgeir E., Sigurpalsdottir, Brynja, Sveinbjornsson, Gardar, Eggertsson, Hannes P., Magnusson, Sigurdur H., Oddsson, Asmundur, Bjornsdottir, Anna, Vikingsson, Arnor, Sveinsson, Olafur A., Hrafnsdottir, Maria G., Sigurdardottir, Gudrun R., Halldorsson, Bjarni V., Hansen, Thomas Folkmann, Paarup, Helene, Erikstrup, Christian, Nielsen, Kaspar, Klokker, Mads, Bruun, Mie Topholm, Sorensen, Erik, Banasik, Karina, Burgdorf, Kristoffer S., Pedersen, Ole Birger, Ullum, Henrik, Jonsdottir, Ingileif, Stefansson, Hreinn, and Stefansson, Kari
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- 2021
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47. Acute and persistent symptoms in non-hospitalized PCR-confirmed COVID-19 patients
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Bliddal, Sofie, Banasik, Karina, Pedersen, Ole Birger, Nissen, Janna, Cantwell, Lisa, Schwinn, Michael, Tulstrup, Morten, Westergaard, David, Ullum, Henrik, Brunak, Søren, Tommerup, Niels, Feenstra, Bjarke, Geller, Frank, Ostrowski, Sisse Rye, Grønbæk, Kirsten, Nielsen, Claus Henrik, Nielsen, Susanne Dam, and Feldt-Rasmussen, Ulla
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- 2021
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48. Herpes Simplex Virus Type 1 infection is associated with suicidal behavior and first registered psychiatric diagnosis in a healthy population
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Nissen, Janna, Trabjerg, Betina, Pedersen, MG, Banasik, Karina, Pedersen, Ole Birger, Sørensen, Erik, Nielsen, Kaspar René, Erikstrup, Christian, Petersen, Mikkel Steen, Paarup, Helene Martina, Bruun-Rasmussen, Peter, Westergaard, David, Hansen, TF, Pedersen, Carsten B., Werge, Thomas, Torrey, Fuller, Hjalgrim, Henrik, Mortensen, Preben Bo, Yolken, Robert, Brunak, Søren, Ullum, Henrik, and Burgdorf, KS
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- 2019
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49. Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration
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Jennison, Christopher, Ehrhardt, Beate, Baum, Patrick, Schoelsch, Corinna, Freijer, Jan, Grempler, Rolf, Graefe-Mody, Ulrike, Hennige, Anita, Dings, Christiane, Lehr, Thorsten, Scherer, Nina, Sihinecich, Iryna, Pattou, Francois, Raverdi, Violeta, Caiazzo, Robert, Torres, Fanelly, Verkindt, Helene, Mari, Andrea, Tura, Andrea, Giorgino, Toni, Bizzotto, Roberto, Froguel, Philippe, Bonneford, Amelie, Canouil, Mickael, Dhennin, Veronique, Brorsson, Caroline, Brunak, Soren, De Masi, Federico, Gudmundsdóttir, Valborg, Pedersen, Helle, Banasik, Karina, Thomas, Cecilia, Sackett, Peter, Staerfeldt, Hans-Henrik, Lundgaard, Agnete, Nilsson, Birgitte, Nielsen, Agnes, Mazzoni, Gianluca, Karaderi, Tugce, Rasmussen, Simon, Johansen, Joachim, Allesøe, Rosa, Fritsche, Andreas, Thorand, Barbara, Adamski, Jurek, Grallert, Harald, Haid, Mark, Sharma, Sapna, Troll, Martina, Adam, Jonathan, Ferrer, Jorge, Eriksen, Heather, Frost, Gary, Haussler, Ragna, Hong, Mun-gwan, Schwenk, Jochen, Uhlen, Mathias, Nicolay, Claudia, Pavo, Imre, Steckel-Hamann, Birgit, Thomas, Melissa, Adragni, Kofi, Wu, Han, Hart, Leen't, Roderick, Slieker, van Leeuwen, Nienke, Dekkers, Koen, Frau, Francesca, Gassenhuber, Johann, Jablonka, Bernd, Musholt, Petra, Ruetten, Hartmut, Tillner, Joachim, Baltauss, Tania, Bernard Poenaru, Oana, de Preville, Nathalie, Rodriquez, Marianne, Arumugam, Manimozhiyan, Allin, Kristine, Engelbrechtsen, Line, Hansen, Torben, Hansen, Tue, Forman, Annemette, Jonsson, Anna, Pedersen, Oluf, Dutta, Avirup, Vogt, Josef, Vestergaard, Henrik, Laakso, Markku, Kokkola, Tarja, Kuulasmaa, Teemu, Franks, Paul, Giordano, Nick, Pomares-Millan, Hugo, Fitipaldi, Hugo, Mutie, Pascal, Klintenberg, Maria, Bergstrom, Margit, Groop, Leif, Ridderstrale, Martin, Atabaki Pasdar, Naeimeh, Deshmukh, Harshal, Heggie, Alison, Wake, Dianne, McEvoy, Donna, McVittie, Ian, Walker, Mark, Hattersley, Andrew, Hill, Anita, Jones, Angus, McDonald, Timothy, Perry, Mandy, Nice, Rachel, Hudson, Michelle, Thorne, Claire, Dermitzakis, Emmanouil, Viñuela, Ana, Cabrelli, Louise, Loftus, Heather, Dawed, Adem, Donnelly, Louise, Forgie, Ian, Pearson, Ewan, Palmer, Colin, Brown, Andrew, Koivula, Robert, Wesolowska-Andersen, Agata, Abdalla, Moustafa, McRobert, Nicky, Fernandez, Juan, Jiao, Yunlong, Robertson, Neil, Gough, Stephen, Kaye, Jane, Mourby, Miranda, Mahajan, Anubha, McCarthy, Mark, Shah, Nisha, Teare, Harriet, Holl, Reinhard, Koopman, Anitra, Rutters, Femke, Beulens, Joline, Groeneveld, Lenka, Bell, Jimmy, Thomas, Louise, Whitcher, Brandon, Wilman, Henry R., Parisinos, Constantinos A., Atabaki-Pasdar, Naeimeh, Kelly, Matt, Thomas, E. Louise, Neubauer, Stefan, Hingorani, Aroon D., Patel, Riyaz S., Hemingway, Harry, Franks, Paul W., Bell, Jimmy D., Banerjee, Rajarshi, and Yaghootkar, Hanieh
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- 2019
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50. Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
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Burgdorf, Kristoffer Sølvsten, Trabjerg, Betina B., Pedersen, Marianne Giørtz, Nissen, Janna, Banasik, Karina, Pedersen, Ole Birger, Sørensen, Erik, Nielsen, Kaspar René, Larsen, Margit Hørup, Erikstrup, Christian, Bruun-Rasmussen, Peter, Westergaard, David, Thørner, Lise Wegner, Hjalgrim, Henrik, Paarup, Helene Martina, Brunak, Søren, Pedersen, Carsten B., Torrey, E. Fuller, Werge, Thomas, Mortensen, Preben Bo, Yolken, Robert H., and Ullum, Henrik
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- 2019
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