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14. Real-world practice patterns of eplerenone use for central serous chorioretinopathy.

Author

Venkatesh, Ramesh, Prabhu, Vishma, Joshi, Aishwarya, Mangla, Rubble, Singh, Rishi, Wu, Lihteh, Lanzetta, Paolo, Bandello, Francesco, Cohen, Francine, Chhablani, Jay, and Kuppermann, Baruch

Subjects
Central serous chorioretinopathy, Eplerenone, Real-world patterns, Side-effects, Treatment
Abstract

PURPOSE: To report eplerenone use by retina specialists worldwide for central serous chorioretinopathy (CSCR). METHODS: A self-reporting questionnaire was distributed to retina specialists worldwide to gather clinicians perspectives on CSCR cases treated, eplerenone dosage and duration, reasons to use it, and side effects. RESULTS: The survey included 241 retina specialists (122 Indian and 119 international) with an average experience of 15.69 ± 9.59 years. Oral eplerenone was used to treat CSCR by 149 (62%) participants. Only 6% (n = 9) had easy access to verteporfin dye and photodynamic therapy. 30 (20%) of the 149 respondents changed their treatment with eplerenone after VICI trial results. Eplerenone was prescribed mostly for chronic CSCR (n = 86, 58%), regardless of involvement laterality. 62% (n = 92) had fewer than 25% CSCR cases treated with eplerenone. 85 (57%) respondents used eplerenone only when other treatments failed, while 36 (24%) used it as first-line treatment. 73 (49%) respondents, prescribed eplerenone at a 50 mg daily dose and 137 (92%) retina specialists used eplerenone for 0-3 months. The drugs efficacy dissatisfied 21 (14%) study participants. 124 (83%) study participants did not encounter any ocular or systemic side effects with eplerenone use. Eplerenone related kidney and electrolyte issues were noted by 11 (7%) study participants. CONCLUSION: The treatment of CSCR varies around the world and is primarily influenced by the photodynamic therapy availability and the findings of VICI trial. Despite the limited benefit of eplerenone reported by the VICI trial, it is still used as evidenced by real-world experience. TRIAL REGISTRATION NUMBER: Not applicable.

Published
2023

22. Bibliometric analysis of academic journal recommendations and requirements for surgical and anesthesiologic adverse events reporting.

Author

Sholklapper, Tamir, Ballon, Jorge, Sayegh, Aref, La Riva, Anibal, Perez, Laura, Huang, Sherry, Eppler, Michael, Nelson, Gregg, Marchegiani, Giovanni, Hinchliffe, Robert, Gordini, Luca, Furrer, Marc, Brenner, Michael, Dell-Kuster, Salome, Biyani, Chandra, Francis, Nader, Kaafarani, Haytham, Siepe, Matthias, Winter, Des, Bandello, Francesco, Siemens, Robert, Walz, Jochen, Briganti, Alberto, Gratzke, Christian, Abreu, Andre, Desai, Mihir, Sotelo, Rene, Agha, Riaz, Lillemoe, Keith, Wexner, Steven, Collins, Gary, Gill, Inderbir, Cacciamani, Giovanni, and Sosa, Julie Ann

Subjects
Humans, Anesthesiology, Bibliometrics, Journal Impact Factor, Europe, Middle East
Abstract

BACKGROUND: Standards for reporting surgical adverse events (AEs) vary widely within the scientific literature. Failure to adequately capture AEs hinders efforts to measure the safety of healthcare delivery and improve the quality of care. The aim of the present study is to assess the prevalence and typology of perioperative AE reporting guidelines among surgery and anesthesiology journals. MATERIALS AND METHODS: In November 2021, three independent reviewers queried journal lists from the SCImago Journal & Country Rank (SJR) portal (www.scimagojr.com), a bibliometric indicator database for surgery and anesthesiology academic journals. Journal characteristics were summarized using SCImago, a bibliometric indicator database extracted from Scopus journal data. Quartile 1 (Q1) was considered the top quartile and Q4 bottom quartile based on the journal impact factor. Journal author guidelines were collected to determine whether AE reporting recommendations were included and, if so, the preferred reporting procedures. RESULTS: Of 1409 journals queried, 655 (46.5%) recommended surgical AE reporting. Journals most likely to recommend AE reporting were: by category surgery (59.1%), urology (53.3%), and anesthesia (52.3%); in top SJR quartiles (i.e. more influential); by region, based in Western Europe (49.8%), North America (49.3%), and the Middle East (48.3%). CONCLUSIONS: Surgery and anesthesiology journals do not consistently require or provide recommendations on perioperative AE reporting. Journal guidelines regarding AE reporting should be standardized and are needed to improve the quality of surgical AE reporting with the ultimate goal of improving patient morbidity and mortality.

Published
2023

23. List of contributors

Author

Mirshahi, Reza, primary, Fallon, Julia, additional, Acar, Burak, additional, Acharya, Isha, additional, Agarwal, Aniruddha, additional, Agrawal, Kushal, additional, Ahsanuddin, Sofia, additional, Alforja, Socorro, additional, Aljneibi, Shaikha, additional, Arévalo, J. Fernando, additional, Ayachit, Apoorva, additional, Ayachit, Guruprasad, additional, Baek, Jiwon, additional, Bandello, Francesco, additional, Baumal, Caroline R., additional, Bernal-Morales, Carolina, additional, Bertelli, Pietro M., additional, Bharath, Abhinaya, additional, Biswas, Jyotirmay, additional, Blindbæk, Søren Leer, additional, Bonhomme, Gabrielle, additional, Bonilla, Alan Chew, additional, Bonnin, Sophie, additional, Borrelli, Enrico, additional, Bousquet, Elodie, additional, Caranfa, Jonathan T., additional, Cassoux, Nathalie, additional, Chatziralli, Irini, additional, Checchin, Lisa, additional, Chhablani, Jay, additional, Chotcomwongse, Peranut, additional, Choudhry, Netan, additional, Chui, Toco, additional, Cruz-Pimentel, Miguel, additional, Eandi, Chiara M., additional, El Moussawi, Zeinab, additional, Errera, Marie-Helene, additional, Espejo-Arjona, Francisco, additional, Eyre, Jessica, additional, Falavarjani, Khalil Ghasemi, additional, Gallego-Pinazo, Roberto, additional, Gaudric, Alain, additional, Gonzalez, Monica P., additional, Grauslund, Jakob, additional, Guduric-Fuchs, Jasenka, additional, Guerra, Ricardo Leitão, additional, Gutiérrez-Bonet, Rosa, additional, Handa, Ashit, additional, Iovino, Claudio, additional, Jones, Anthony A., additional, Joshi, Shrinivas, additional, Kim, Judy E., additional, Kodjikian, Laurent, additional, Kulikov, Alexey N., additional, Labay-Tejado, Sara, additional, Ledesma-Gil, Gerardo, additional, Lippincott, John K., additional, Lois, Noemi, additional, Lupidi, Marco, additional, Mainster, Martin A., additional, Malaise, Denis, additional, Maltsev, Dmitrii S., additional, Mammo, Danny A., additional, Mangla, Rubble, additional, Mansour, Hana A., additional, Mansour, Ahmad M., additional, Mariotti, Cesare, additional, Matet, Alexandre, additional, Mathis, Thibaud, additional, Medina, Reinhold J., additional, Melo, Isabela Martins, additional, Menendez-Acebal, Covadonga, additional, Micevych, Paul S., additional, Montesel, Andrea, additional, Montolío-Marzo, Santiago, additional, Muni, Rajeev H., additional, Muñoz-Solano, Javier, additional, Muzi, Alessio, additional, Neto, Laurentino Biccas, additional, Ong, Joshua, additional, Ong, Sally S., additional, Orr, Samantha, additional, Özdek, Şengül, additional, Pacques, Michel, additional, Pappelis, Konstantinos, additional, Pathak, Varun, additional, Pattathil, Niveditha, additional, Pearce, Thomas M., additional, Penha, Fernando M., additional, Pichi, Francesco, additional, Poireir, Matthieu, additional, Prabhu, Vishma, additional, Querques, Giuseppe, additional, Rachitskaya, Aleksandra V., additional, Rahimi Ardali, Kimia, additional, Raval, Vishal, additional, Raval, Nilesh, additional, Reddy, Nikitha Gurram, additional, Reibaldi, Michele, additional, Reid, Emma, additional, Ricardi, Federico, additional, Rosen, Richard, additional, Rosier, Laurence, additional, Ruamviboonsuk, Paisan, additional, Ruiz-Medrano, Jorge, additional, Ruiz-Moreno, José M., additional, Sacconi, Riccardo, additional, Santina, Ahmad, additional, Sarraf, David, additional, Schwartz, Carol E., additional, Scott, Adrienne W., additional, Shaheen, Abdulla R., additional, Silpa-archa, Sukhum, additional, Singh, Sumit Randhir, additional, Sivalingam, Meera D., additional, Sridhar, Jayanth, additional, Stewart, Jay M., additional, Stitt, Alan W., additional, Tadarati, Mongkol, additional, Thariat, Juliette, additional, Turgut, Burak, additional, Venkatesh, Ramesh, additional, Vergmann, Anna Stage, additional, Vidal-Oliver, Lourdes, additional, Vujosevic, Stela, additional, Wakabayashi, Taku, additional, Wang, Kristine, additional, Wu, Lihteh, additional, Wu, Andres, additional, Wu, Max, additional, Yonekawa, Yoshihiro, additional, Zarnegar, Arman, additional, Zarranz-Ventura, Javier, additional, Zeydanli, Ece Ozdemir, additional, Zhang, Xinyuan, additional, and Zucchiatti, Ilaria, additional

Published
2024
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48. Natural history of patients with Leber hereditary optic neuropathy-results from the REALITY study.

Author

Yu-Wai-Man, Patrick, Newman, Nancy, Carelli, Valerio, La Morgia, Chiara, Biousse, Valérie, Bandello, Francesco, Clermont, Catherine, Campillo, Lorena, Leruez, Stephanie, Moster, Mark, Cestari, Dean, Foroozan, Rod, Sadun, Alfredo, Karanjia, Rustum, Jurkute, Neringa, Blouin, Laure, Taiel, Magali, and Sahel, José-Alain

Subjects
Adolescent, Adult, DNA, Mitochondrial, Europe, Humans, Mutation, Optic Atrophy, Hereditary, Leber, Retrospective Studies
Abstract

BACKGROUND/OBJECTIVES: REALITY is an international observational retrospective registry of LHON patients evaluating the visual course and outcome in Leber hereditary optic neuropathy (LHON). SUBJECTS/METHODS: Demographics and visual function data were collected from medical charts of LHON patients with visual loss. The study was conducted in 11 study centres in the United States of America and Europe. The collection period extended from the presymptomatic stage to at least more than one year after onset of vision loss (chronic stage). A Locally Weighted Scatterplot Smoothing (LOWESS) local regression model was used to analyse the evolution of best-corrected visual acuity (BCVA) over time. RESULTS: 44 LHON patients were included; 27 (61%) carried the m.11778G>A ND4 mutation, 8 (18%) carried the m.3460G>A ND1 mutation, and 9 (20%) carried the m.14484T>C ND6 mutation. Fourteen (32%) patients were under 18 years old at onset of vision loss and 5 (11%) were below the age of 12. The average duration of follow-up was 32.5 months after onset of symptoms. At the last observed measure, mean BCVA was 1.46 LogMAR in ND4 patients, 1.52 LogMAR in ND1 patients, and 0.97 LogMAR in ND6 patients. The worst visual outcomes were reported in ND4 patients aged at least 15 years old at onset, with a mean BCVA of 1.55 LogMAR and no tendency for spontaneous recovery. The LOESS modelling curve depicted a severe and permanent deterioration of BCVA. CONCLUSIONS: Amongst LHON patients with the three primary mtDNA mutations, adult patients with the m.11778G>A ND4 mutation had the worst visual outcomes, consistent with prior reports.

Published
2022

50. Faricimab Treat-and-Extend for Diabetic Macular Edema: Two-Year Results from the Randomized Phase 3 YOSEMITE and RHINE Trials

Author

Aaberg, Thomas, Jr., Abbey, Ashkan, Abdulaeva, Elmira, Abengoechea, Santiago, Abraham, Prema, Ach, Thomas, Adams, Serrhel, Adan Civera, Alfredo, Adrean, Sean, Agostini, Hansjurgen, Alam, Suhail, Alezzandrini, Arturo, Alfaro, Virgil, Aliseda, Daniel, Almony, Arghavan, Amat, Pedro, Amini, Payam, Antoszyk, Andrew, Arias, Luis, Asaria, Riaz, Avila, Marcos, Awh, Carl C., Bafalluy, Joaquin, Baker, Carl, Bandello, Francesco, Barakat, Mark, Barraza, Karen, Bator, Gyorgy, Baumal, Caroline, Belfort, Rubens, Jr., Bergstrom, Chris, Bertolucci, George, Bochow, Thomas, Bolz, Matthias, Borcz, Emilia, Bordon, Arnaldo, Boyer, David, Bratko, Galina, Brent, Michael, Brown, Jamin, Brown, David M., Budzinskaya, Maria, Buffet, Sylvia, Burgess, Stuart, Burton, Ben, Busquets, Miguel, Cabrera, Francisco, Cagini, Carlo, Calzada, Jorge, Campochiaro, Peter, Carlson, John, Castellarin, Alessandro, Cava, Carlos, Chaikitmongkol, Voraporn, Chan, Clement, Chang, Emmanuel, Chang, Jonathan, Chang, Andrew, Charles, Steve, Chaudhry, Nauman, Chee, Caroline, Chen, Judy, Chen, Fred, Chen, Shih-Jen, Cheong-Leen, Richard, Chiang, Allen, Chittum, Mark, Chow, David, Connolly, Brian, Cornut, Pierre Loic, Csaky, Karl, Danzig, Carl, Das, Arup, Daskalov, Vesselin, Desco, Carmen, Dessouki, Amr, Dickinson, John, Do, Brian, Dollin, Michael, Dugel, Pravin, Dusova, Jaroslava, Eichenbaum, David, Eldem, Bora, Engstrom, Robert, Ernest, Jan, Escobar, Joan Josep, Esposti, Simona, Eter, Nicole, Falk, Naomi, Farkas, Andrej, Feiner, Leonard, Feltgen, Nicolas, Fernandez, Carlos, Fernandez Vega, Alvaro, Ferrone, Philip, Figueira, Joao, Figueroa, Marta, Findl, Oliver, Fine, Howard, Fortun, Jorge, Fox, Gregory M., Foxman, Scott, Framme, Carsten, Fraser-Bell, Samantha, Fu, Arthur, Fukutomi, Akira, Fung, Nicholas, Furno Sola, Federico, Gallego-Pinazo, Roberto, Garcia, Renata, Garcia-Layana, Alfredo, Gawecki, Maciej, George, Sheen, Ghanchi, Faruque, Ghorayeb, Ghassan, Goldberg, Roger, Goldstein, Michaella, Gomes, Nuno, Ulla, Francisco Gomez, Gonzalez, Victor, Greven, Craig, Gupta, Sunil, Guzman, Miguel, Harris, Martin, Hatz, Katja, Hau, Vivienne, Hau, Vincent, Hayashi, Ken, Heier, Jeffrey, Herba, Ewa, Hershberger, Vrinda, Higgins, Patrick, Hirakata, Akito, Ho, Allen, Holekamp, Nancy, Honda, Shigeru, Hsu, Jason, Hu, Allen, Hurcikova, Maria, Ikeda, Yasuhiro, Isernhagen, Ricky, Ito, Yasuki, Jackson, Tim, Jacoby, Rachael, Jafree, Afsar, Javey, Golnaz, Javid, Cameron, Jhaveri, Chirag, Johnson, Mark, Kacerík, Marek, Kaluzny, Jakub, Kampik, Daniel, Kang, Se Woong, Kapoor, Kapil, Karabas, Levent, Kawasaki, Tsutomu, Kerenyi, Agnes, Khanani, Arshad, Khurana, Rahul, Kim, Brian, Kimura, Kazuhiro, Kishino, Genichiro, Kitano, Shigehiko, Klein-Mascia, Kendra, Kokame, Gregg, Korobelnik, Jean Francois, Kulikov, Alexey, Kuriyan, Ajay, Kwong, Henry, Kwun, Robert, Lai, Timothy, Lai, Chi-Chun, Laird, Philip, Lalonde, Laurent, Lanzetta, Paolo, Larsen, Michael, Laugesen, Caroline, Lavinsky, Daniel, Lebreton, Olivier, Lee, Seong, Levy, Jaime, Lipkova, Blandina, Liu, Mimi, Liu, Judy, Lohmann, Chris P., London, Nikolas, Lorenz, Katrin, Lotery, Andrew, Lozano Rechy, David, Lujan, Silvio, Ma, Patrick, Maeno, Takatoshi, Mahmood, Sajjad, Makkouk, Fuad, Malik, Khurram, Marcus, Dennis, Margherio, Alan, Mastropasqua, Leonardo, Maturi, Raj, McCabe, Frank, McKibbin, Martin, Mehta, Hemal, Menon, Geeta, Mentes, Jale, Michalska-Malecka, Katarzyna, Misheva, Aneta, Mitamura, Yoshinori, Mitchell, Paul, Modi, Yasha, Mohamed, Quresh, Montero, Javier, Moore, Jeffrey, Morales Canton, Virgilio, Morori-Katz, Haia, Morugova, Tatiana, Murakami, Tomoaki, Muzyka-Wozniak, Maria, Nardi, Marco, Nemcansky, Jan, Nester-Ostrowska, Kamila, Neto, Julio, Newell, Charles, Nicolo, Massimo, Nielsen, Jared, Noda, Kousuke, Obana, Akira, Ogata, Nahoko, Oh, Hideyasu, Oh, Kean, Ohr, Matthew, Oleksy, Piotr, Oliver, Scott, Olivier, Sebastien, Osher, James, Ozcalışkan, Sehnaz, Ozturk, Banu, Papp, Andras, Park, Kyu Hyung, Parke, D. Wilkin, Parravano, Maria Cristina, Patel, Sugat, Patel, Sunil, Pearce, Ian, Pearlman, Joel, Penha, Fernando, Perente, Irfan, Perkins, Stephen, Pertile, Grazia, Petkova, Iva, Peto, Tunde, Pieramici, Dante, Pollreisz, Andreas, Pongsachareonnont, Pear, Pozdeyeva, Nadezhda, Priglinger, Siegfried, Qureshi, Jawad, Raczynska, Dorota, Rajagopalan, Rajesh, Ramirez Estudillo, Juan, Raskauskas, Paul, Rathod, Rajiv, Razavi, Hessam, Regillo, Carl, Ricci, Federico, Rofagha, Soraya, Romanczak, Dominika, Romanowska-Dixon, Bożena, Rosberger, Daniel, Rosenblatt, Irit, Rosenblatt, Brett, Ross, Adam, Ruamviboonsuk, Paisan, Ruiz Moreno, Jose Maria, Salomão, Gustavo, Sandhu, Sukhpal, Sandner, Dirk, Sararols, Laura, Sawada, Osamu, Schadlu, Ramin, Schlottmann, Patricio, Schuart, Claudia, Seitz, Berthold, Seres, András, Sermet, Figen, Shah, Sandeep, Shah, Ankur, Shah, Rohan, Sharma, Sumit, Sheidow, Thomas, Sheth, Veeral, Shimouchi, Akito, Shimura, Masahiko, Sikorski, Bartosz, Silva, Rufino, Singer, Michael, Singerman, Lawrence, Singh, Rishi, Souied, Eric, Spinak, David J., Spital, Georg, Steinle, Nathan, Stern, Jeffrey, Stoller, Glenn, Stoltz, Robert, Stone, Cameron, Stone, Amy, Suan, Eric, Sugimoto, Masahiko, Sugita, Iichiro, Sun, Jennifer, Sun, Xiaodong, Suner, Ivan, Szalczer, Lajos, Szecsko, Timea, Tabassian, Ali, Tadayoni, Ramin, Takagi, Hitoshi, Takayama, Kei, Taleb, Alexandre, Talks, James, Tan, Gavin, Tanabe, Teruyo, Taylor, Stanford, Thach, Allen, Thompson, John, Tlucek, Paul, Torti, Robert, Tosheva Guneva, Daniela, Toth-Molnar, Edit, Uchiyama, Eduardo, Vajas, Attila, Varma, Deepali, Varsanyi, Balazs, Vassileva, Petja, Vaz-Pereira, Sara, Veith, Miroslav, Vela, Jose Ignacio, Viola, Francesco, Virgili, Gianni, Vogt, Gábor, Vorum, Henrik, Weber, Pamela, Wecke, Thoalf, Wee, Raymond, Weger, Martin, Weishaar, Paul, Wells, John A., Wickremasinghe, Sanjeewa, Williams, Thomas Reginald, Williams, Thomas, Williams, Geoff, Wolf, Armin, Wolfe, Jeremy, Wong, James, Wong, David, Wong, Ian, Wong, Robert, Wowra, Bogumil, Wykoff, Charles C., Wylęgała, Edward, Yang, Chang-Hao, Yasukawa, Tsutomu, Yates, Paul, Yilmaz, Gursel, Yiu, Glenn, Yoon, Young Hee, Yoreh, Barak, Yoshida, Shigeo, Yu, Hyeong Gon, Yu, Seung Young, Yurieva, Tatiana, Zacharias, Leandro, Zaczek Zakrzewska, Karolina, Zambrano, Alberto, Zatorska, Barbara, Zeolite, Carlos, Zheutlin, Jeffrey, Wong, Tien Y., Haskova, Zdenka, Asik, Kemal, Baumal, Caroline R., Csaky, Karl G., Ives, Jane A., Jaffe, Glenn J., Korobelnik, Jean-François, Lin, Hugh, Murata, Toshinori, Schlottmann, Patricio G., Seres, András I., Silverman, David, and Tang, Yannan

Published
2024
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