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Purpose: To estimate the effect of simvastatin gel in the osseointegration of dental implants using bone scintigraphy., Materials and Methods: A total of 20 participants with missing mandibular first molars and D2 type bone were assigned equally to two groups. Group A received 1.2% simvastatin and group B received placebo gels during the placement of implants. The participants were subjected to bone scintigraphy to determine the osteoblastic activity at baseline, 30 days, and 90 days after implant placement., Results: Group A had a significant increase in osteoblastic activity between baseline, day 30, and day 90 (P < .05), with a higher mean of 100.06% ± 21.644% on day 30. Group B had a significant increase in osteoblastic activity only between baseline and day 30 and between baseline and day 90 (P < .05). There was no difference between days 30 and 90 (P > .05), with a higher mean of 79.20% ± 18.255% on day 30. A bivariate analysis performed at different time periods revealed a significant difference between groups A and B on day 30., Conclusions: Implants placed with 1.2% simvastatin gel showed enhanced osteoblastic activity in the 4th week after implant placement, indicating that there was a faster rate of osseointegration at an early stage.

Purpose: To evaluate and compare the changes in brain activity for individuals with a single missing mandibular molar replaced with a removable dental prosthesis (RPD) and a fixed tooth-supported implant prosthesis in the static and postmasticatory phases., Materials and Methods: In total, 24 patients with a unilateral missing mandibular first molar were rehabilitated with a removable dental prosthesis and divided into two groups of 12 each; Group A was rehabilitated with implants and Group B with 3-unit tooth-supported fixed partial dentures (FPDs). An electroencephalogram (EEG) was taken during the three phases of assessment: (1) before insertion of any prosthesis (N0), (2) after insertion of an RPD (N1), and (3) after cementation of an FPD or implant crown (F2). The effect of bite force with RPD (N1M) and FPD or implant prosthesis (F2M) on alpha waves was evaluated by recording EEG immediately after chewing gum for 30 seconds., Results: The improvement of the amplitude of alpha waves before and after prosthesis insertion showed a significant difference between Group As and B (P < .05) with the highest mean values of 158.3 µV, 147.9 µV, and 182.1 µV occurring in pairs F2-N0, F2-N1, and F2M-N1M, respectively, for Group A. Similarly, for the power of alpha waves between group A and B, a statistically significant difference (P < .05) with the highest mean values of 30.3 dB, 28.9 dB, 36.9 dB, and 11.2 dB in pairs F2-N0, F2-N1, F2M-N1M, and F2M-F2 ,respectively, was observed for Group A. There was no statistically significant increase in pair N0-N1 (P > .05)., Conclusions: Replacement of a single missing tooth enhanced brain activity and was highest with an implant-supported crown. Int J Prosthodont 2023;36:563-569.

Aim: To identify the body image perception of an individual utilising figure rating scale and assess its psychological influence in altering the prosthetic satisfaction., Methods: One hundred five of 140 participants were categorised into Groups I, II and III according to their body image satisfaction. Pre- and posttreatment denture satisfaction questionnaires, and pretreatment Big Five personality, Life Satisfaction questionnaires were given to the participants in each group. Analysis of variance (ANOVA) and Tukey post hoc tests assessed the significant relation between the groups., Results: Body image satisfied group (I) was highly contented with the prosthetic treatment (46.90), while body image dissatisfied groups (II and III) had lower denture satisfaction scores (36.80 and 29.70). Neurotic score was significantly different in pairs; Groups I and III, and Groups II and III (P < .001), with high mean for Group III (75.30). The agreeable score was significantly different in Groups I and II (P < .05), with a high mean for Group I (83.60). Life Satisfaction score was significantly different in pairs; Groups I and III, and Groups I and II (P < .001), with a high mean for Group I (30.60)., Conclusion: The individual's perception of body image had an effect on their denture satisfaction level, and figure rating scale would help in identifying the psychological profile of the patient., (© 2020 Special Care Dentistry Association and Wiley Periodicals LLC.)

Background: The relationship between brain and prosthesis was previously assessed either by improving denture function or in fixed implant retained, wherein brain function was assessed only after crown placement., Purpose: To prospectively analyze the changes in brain activity and cognitive function of completely edentulous patients in edentulous state, with dentures and two-implant supported mandibular overdenture before and after loading, along with the effect of mastication in the change - a pilot study., Materials and Method: Ten completely edentulous (CE) non-denture wearers were selected. The mandibular prosthesis was loaded with two 3.3 mm × 13 mm myriad snap fit implants. To assess the brain activity and cognitive function, Electroencephalogram (Neurofax EEG 1000 Ver 05-90, Nihon Kohden corporation, Tokyo, Japan) and Mini-Mental State Examination (MMSE) questionnaire, respectively, were taken during the process of rehabilitation. EEG assessment was analyzed using Matlab 2011A 7.9 signal processing tool box. The results were statistically analyzed with SPSS 17.0 version using Wilcoxon signed rank and Friedman test, Results: Amplitude, power of alpha waves and cognitive scores increased gradually with highest mean rank for implant supported overdenture (IOD). The bivariate analysis between two groups showed there was significant difference between all the groups (p < 0.05) except for groups CE-I (completely edentulous - implant placement) and CD- I (complete denture insertion - implant placement) in amplitude of alpha waves while in group CD-I with respect to power of alpha waves. MMSE revealed the mean of cognitive scores in Complete Edentulous was 17.40, Complete Denture was 18.30 and finally with Implant Overdenture was 23.80., Conclusion: The present study has enlightened the significance of two implant supported mandibular overdenture in improving the mental state of an individual and that the enhancement was due to functional improvement with prosthesis when loaded with implants and not due to mere existence of implant without any function., (© 2015 Wiley Periodicals, Inc.)