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Your search keyword '"Bao, Xiulan"' showing total 24 results
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24 results on '"Bao, Xiulan"'

7. Structure Design and Performance Analysis of a Novel Pole-climbing Robot

Author

Bao Xiulan, Wang Lintao, Huang Jiayun, Gan Di, Huangfu Jixuan, and Mao Jincheng

Subjects
Pole-climbing robot, Gait analysis, Virtual prototype, Dynamics simulation, Mechanical engineering and machinery, TJ1-1570
Abstract

A novel pole-climbing robot is proposed for the cleaning and maintenance of urban pole-shaped buildings,by using a drive mechanism to complete the movement and clamping. The gait of the robot during climbing process is studied. The virtual prototype of the climbing robot is established. The climbing process of the robot is simulated by using ADAMS,which is multi-rigid body dynamics simulation software.The changing situation of displacement of the robot,torque of the motor and gripping force of the manipulator are analyzed. The simulation results show that the robot can complete the smooth movement according to the intended direction. The motor torque has fluctuation,but the climbing stability of the robot is not affected. The average contact force between the unilateral manipulator and the lamp poles is 32. 4 N. The robot has a good adaptability for the diameter variation of poles.

Published
2017
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24. A novel mutation of the growth hormone receptor gene (GHR) in a Chinese girl with Laron syndrome.

Author

Chen X, Song F, Dai Y, Bao X, and Jin Y

Subjects
Age Determination by Skeleton methods, Alleles, Base Sequence, Carrier Proteins blood, Carrier Proteins drug effects, Carrier Proteins genetics, Child, China, Conserved Sequence genetics, Dwarfism, Pituitary diagnosis, Dwarfism, Pituitary physiopathology, Exons, Female, Growth Hormone blood, Homozygote, Humans, Insulin-Like Growth Factor Binding Protein 3 blood, Insulin-Like Growth Factor I metabolism, Lysine biosynthesis, Lysine genetics, Polymorphism, Single-Stranded Conformational, Receptors, Somatotropin drug effects, Receptors, Somatotropin physiology, Sequence Homology, Nucleic Acid, Asian People, Dwarfism, Pituitary genetics, Point Mutation genetics, Receptors, Somatotropin genetics
Abstract

Laron syndrome, also known as growth hormone insensitivity syndrome (GHIS), is an autosomal recessive genetic disorder associated with severe postnatal growth failure, and normal and/or elevated growth hormone. This disease is frequently caused by a point mutation in the growth hormone receptor gene (GHR). Here, we identified a novel homozygous substitution mutation (E42K: GAG-->AAG at codon 42 cDNA) of the GHR gene in a Chinese girl with Laron syndrome. This mutation was predicted to impair the GHR binding affinity to human growth hormone (hGH), and was responsible for low levels of insulin-like growth factor (IGF)-I, IGF binding protein (IGFBP)-3, and GH binding protein (GHBP) in serum.

Published
2003
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