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1. Diagnosis, treatment, and follow-up of patients with hypophosphatasia

Author

Cárdenas-Aguilera, Juan Guillermo, González-López, Vladimir, Zarante-Bahamón, Ana María, Prieto-Rivera, Juan Carlos, Baquero-Rodríguez, Richard, Chacón-Acevedo, Kelly Rocío, Meza-Martínez, Adriana Isabel, Serrano-Gayubo, Ana Katherina, Medina-Orjuela, Adriana, Cáceres-Mosquera, Jimena Adriana, Guerrero-Tinoco, Gustavo Adolfo, García-Rueda, María Fernanda, Guarnizo-Zuccardi, Pilar, Herrera-Ortiz, Gilberto, Rojas-Barrera, Carolina, Carrascal-Guzmán, Martha Isabel, Reina-Ávila, María Fernanda, Arguinzoniz-Valenzuela, Sletza Lissette, Belmont-Martínez, Leticia, del-Pino, Mariana, Viterbo, Gisela Lorena, Seijo, Mariana, Calzada-Hernández, Joan, Guerra-Hernández, Norma Elizabeth, and Brunetto, Oscar Héctor

Published
2025
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2. Use of rituximab in pediatric patients with steroidresistant nephrotic syndrome. A single center study

Author

Serna-Higuita, Lina María, Vanegas-Ruiz, Juan José, Serrano-Gayubo, Ana Katherina, Vélez-Echeverri, Catalina, Ochoa-García, Carolina Lucía, Rojas-Rosas, Luisa Fernanda, Baquero-Rodríguez, Richard, Nieto-Ríos, John Fredy, Ocampo-Kohn, Catalina, Aristizábal-Alzate, Arbey, Orozco-Forero, Juan Pablo, Flórez, Jesús Antonio, Zuleta-Tobón, John Jairo, and Zuluaga-Valencia, Gustavo Adolfo

Subjects
Chronic Renal Disease, Immunosuppressive Agents, Mycophenolic Acid, Nephrotic Syndrome, Rituximab, Medicine, Medicine (General), R5-920
Abstract

Introduction: Steroids are the cornerstone of therapy for nephrotic syndrome (NS) with a remission rate as high as 90%. In patients who do not respond to them or are steroid dependent, other immunosuppressive drugs have been used. Although rituximab use in NS is off-label, many authors have published their experience with it. Objective and methods: To describe retrospectively a group of seven children with nephrotic syndrome, either steroid-dependent (SDNS) or steroid- resistant (SRNS), treated with rituximab and mycophenolate, at Pablo Tobón Uribe Hospital, in Medellín, Colombia. Results: Two patients with SDNS and five with SRNS were evaluated; median age at diagnosis was 2 years (p25-75: 1-5); six months after treatment with rituximab there was reduction in proteinuria (93%), in the steroid dose (100%) and in the relapse episodes. However, proteinuria reappeared 12 months after treatment. Conclusion: During the first year after rituximab treatment of NS there is reduction in proteinuria and in the steroid dose, but thereafter there is relapse. It is suggested to carry out another study using a second dose of rituximab one year after the first one.

Published
2015

3. Posterior Nutcracker Syndrome: A Pediatric Case Report and Literature Review

Author

Montoya Montoya, Cristina, Serna Higuita, Lina María, and Baquero Rodríguez, Richard

Subjects
hematuria, proteinuria, pediatrics, renal nutcracker syndrome, Medicine, Medicine (General), R5-920
Abstract

The nutcracker syndrome results from the compression of the left renal vein between the aorta and the superior mesenteric artery, leading to variable and nonspecific symptoms of venous congestion. The most common presentation of this syndrome is the classical or anterior form; however, atypical variants exist, including the posterior nutcracker syndrome, which occurs due to the compression of the left renal vein between the aorta and the lumbar spine. This paper describes the case of a 5-year-old patient with persistent gross hematuria and mild proteinuria, in whom glomerular involvement was ruled out. Given the atypical clinical presentation, an abdominal magnetic resonance angiography was performed, confirming the diagnosis of posterior nutcracker syndrome.

Published
2024
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5. Recomendaciones basadas en guías de práctica clínica sobre diagnóstico, tratamiento y seguimiento de infección de tracto urinario en pacientes pediátricos en Colombia

Author

Bolaños Gómez, Andrea, Motato Moscoso, Héctor Jairo, Freyle Fraija, Lorena, Quiroz Madarriaga, Yesica, Castillo, Mariangel, Ovalle Díaz, Johanna, Chacón Acevedo, Kelly, Cárdenas Aguilera, Juan Guillermo, Beltrán Arroyave, Claudia Patricia, Brand Salazar, Sandra Milena, Cadavid Álvarez, Lina Marcela, Cadena, Yair, Echeverry Muñoz, Jessica, Farelo Trejos, Oscar Luis, Ferreira T., Hugo, Pedraza García, Nedier, Gómez Ceballos, Eduardo Ramiro, Gutiérrez Tobar, Iván Felipe, Larios, Carlos Alberto, Martínez Cáceres, Lida Esperanza, Moreno Gómez, Luz Ángela, Orjuela Rodríguez, Camilo Alberto, Restrepo De Rovetto, Consuelo, Rodríguez Takeuchi, Sara Yukie, Rodríguez Peña, Yazmín, Sierra García, Álexandra, De Los Santos, Yusir, Quiroz, Sierra, Sosa Ávila, Luis Miguel, Suárez Fuentes, María Alejandra, Vélez Echeverri, Catalina, Coronel Rodríguez, Wilfrido, and Baquero Rodríguez, Richard

Published
2023
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7. Expert consensus on evidence-based recommendations for the diagnosis, treatment, and follow-up of X-linked hypophosphatemic rickets (XLH)

Author

Cárdenas Aguilera, Juan Guillermo, primary, Medina-Orjuela, Adriana, additional, Meza-Martínez, Adriana Isabel, additional, Prieto, Juan Carlos, additional, Zarante-Bahamón, Ana María, additional, Cáceres-Mosquera, Jimena Adriana, additional, Mejía-Gaviria, Natalia, additional, Serrano-Gayubo, Ana Katherina, additional, Baquero-Rodríguez, Richard, additional, Chacón-Acevedo, Kelly, additional, Guerrero-Tinoco, Gustavo Adolfo, additional, Uribe-Ríos, Alejandro, additional, García-Rueda, María Fernanda, additional, Abad-Londoño, Verónica, additional, Nossa-Almanza, Sergio Alejandro, additional, Aroca-Martínez, Gustavo, additional, Román-González, Alejandro, additional, Endo-Cáceres, Jorge Alberto, additional, Llano-Linares, Juan Pablo, additional, Florenzano, Pablo, additional, Díaz-Curiel, Manuel, additional, Vaisbich, María Helena, additional, Zanchetta, María Belen, additional, Guerra-Hernández, Norma Elizabeth, additional, Stefano, Eduardo Enrique, additional, and Brunetto, Oscar, additional

Published
2024
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9. Caracterización de los pacientes menores de 18 años con nefritis lúpica en el Hospital Pablo Tobón Uribe y en el Hospital San Vicente Fundación de la ciudad de Medellín, entre 2008 y 2017

Author

Quiñones-Rios, Lorena, primary, Estévez Capacho, Mayra Alexandra, additional, Niño Serna, Laura Fernanda, additional, Hernández Zapata, Lady Johana, additional, Eraso Garnica, Ruth María, additional, Vélez Echeverri, Catalina, additional, and Baquero Rodríguez, Richard, additional

Published
2023
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10. Diagnostic approach and monitoring of chronic kidney disease in the primary care pediatric population.

Author

Carrascal, Martha I., Sánchez-Acosta, Karen J., Herrera Parra, Lina J., Cárdenas-Aguilera, Juan G., Serrano-Gayubo, Ana K., Jiménez-Triana, Clímaco A., Merchán, Lizbeth A., Valbuena-García, Ana Ma., and Baquero-Rodríguez, Richard

Subjects
KIDNEY disease diagnosis, PEDIATRIC nephrology, KIDNEY disease treatments, CHRONIC diseases in children, PRIMARY health care, KIDNEY diseases
Abstract

Copyright of Boletín Médico del Hospital Infantil de México is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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12. Expert consensus on evidence-based recommendations for the diagnosis, treatment, and follow-up of X-linked hypophosphatemic rickets (XLH).

Author

Guillermo Cárdenas-Aguilera, Juan, Medina-Orjuela, Adriana, Isabel Meza-Martínez, Adriana, Carlos Prieto, Juan, María Zarante-Bahamón, Ana, Adriana Cáceres-Mosquera, Jimena, Mejía-Gaviria, Natalia, Katherina Serrano-Gayubo, Ana, Baquero-Rodríguez, Richard, Chacón-Acevedo, Kelly, Adolfo Guerrero-Tinoco, Gustavo, Uribe-Ríos, Alejandro, Fernanda García-Rueda, María, Abad-Londoño, Verónica, Alejandro Nossa-Almanza, Sergio, Aroca-Martínez, Gustavo, Román-González, Alejandro, Alberto Endo-Cáceres, Jorge, Pablo Llano-Linares, Juan, and Florenzano, Pablo

Subjects
X-linked genetic disorders, BONE density, HOMEOSTASIS, RICKETS
Abstract

Copyright of Colombian Journal of Nephrology / Revista Colombiana de Nefrología is the property of Colombian Association of Nephrology & Hypertension and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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13. Consenso colombiano sobre vacunación en pacientes con enfermedad renal crónica

Author

Silva Monsalve, Edwin, primary, Roncancio Villamil, Gustavo Eduardo, additional, Forero, Jessica, additional, Mesa, Juan Gonzalo, additional, Cárdenas Aguilera, Juan Guillermo, additional, Estévez, Mayra, additional, Baquero Rodríguez, Richard, additional, Carrascal, Martha, additional, Beltrán Arroyave, Claudia Patricia, additional, Yomayusa González, Nancy, additional, Rico Fontalvo, Jorge, additional, Aroca, Gustavo, additional, Chacón Acevedo, Kelly Rocío, additional, Camacho Moreno, Germán, additional, López Mora, María José, additional, Garcés Samudio, Carlos Guillermo, additional, Cortés, Jorge Alberto, additional, Gutiérrez Tobar, Iván Felipe, additional, Torres Hernández, Daniela, additional, López, Pio, additional, and Soler Romeo, María José, additional

Published
2022
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14. Diagnosis, treatment, and follow-up of patients with hypophosphatasia

Author

Cárdenas-Aguilera, Juan Guillermo, González-López, Vladimir, Zarante-Bahamón, Ana María, Prieto-Rivera, Juan Carlos, Baquero-Rodríguez, Richard, Chacón-Acevedo, Kelly Rocío, Meza-Martínez, Adriana Isabel, Serrano-Gayubo, Ana Katherina, Medina-Orjuela, Adriana, Cáceres-Mosquera, Jimena Adriana, Guerrero-Tinoco, Gustavo Adolfo, García-Rueda, María Fernanda, Guarnizo-Zuccardi, Pilar, Herrera-Ortiz, Gilberto, Rojas-Barrera, Carolina, Carrascal-Guzmán, Martha Isabel, Reina-Ávila, María Fernanda, Arguinzoniz-Valenzuela, Sletza Lissette, Belmont-Martínez, Leticia, del-Pino, Mariana, Viterbo, Gisela Lorena, Seijo, Mariana, Calzada-Hernández, Joan, Guerra-Hernández, Norma Elizabeth, and Brunetto, Oscar Héctor

Abstract

Introduction: Hypophosphatasia is a rare inherited systemic metabolic disorder, with an estimated prevalence in the severe forms of the disease of 1/100.000–1/300.000, that affects the typical architecture of bone, leading to defective mineralization during growth and remodeling. It is characterized by loss-of-function variants in the ALPLgene, resulting in low activity of tissue-nonspecific alkaline phosphatase. In severe cases, it can be fatal. Objective: To generate recommendations on the diagnosis, treatment, and follow-up of patients with hypophosphatasia based on available evidence. Materials and methods: A search for evidence published between 2012 and 2024 was carried out in Medline and Embase. The search was expanded with information from various sources, including official sites of development groups, consensuses, technology evaluations, Google Scholar, clinical experts, and reference lists. The quality of the evidence was evaluated according to the type of document type. A modified Delphi consensus process was carried out with external experts, apart from the development group, it was established an 80% agreement threshold to define the final recommendations. Results: Sixty-one papers were found in the evidence search. The global quality of the evidence was low. In addition, a consensus was reached on 94 recommendations regarding diagnosis, treatment, and follow-up. Those recommendations were approved by external clinical experts from Colombia, Argentina, Spain, and Mexico. Conclusions: The recommendations proposed in this document are based on the evidence available to the date the search was carried out, and the judgment of clinical experts. The recommendations on diagnosis, treatment, and follow-up are expected to guide the daily clinical practice for patients with HPP.

Published
2024
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16. Recomendaciones basadas en guías de práctica clínica sobre definición, diagnóstico y tratamiento de la enuresis monosintomática en pacientes pediátricos.

Author

Baquero-Rodríguez, Richard, Espitaleta, Zilac, Hugo Figueroa, Víctor, Isabel Meza-Martínez, Adriana, Adriana Cáceres-Mosquera, Jimena, Álvarez-Gómez, Yeferson, Ovalle-Díaz, Johanna, Carolina Bello-Márquez, Diana, Alberto Rodríguez-Ibarra, Carlos, Adolfo Guerrero-Tinoco, Gustavo, Isabel Carrascal-Guzmán, Martha, Freyle-Fraija, Lorena, Esthella González, Luz, Jairo Motato-Moscoso, Héctor, Quintero-Espinosa, Alejandro, Quiroz, Yesica, Marcela Suárez-Barajas, Ehimy, Quiñones-Ríos, Lorena, Bolaños-Gómez, Andrea, and Castillo, Mariangel

Published
2023
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18. Recomendaciones para el uso racional de la prueba 25-hidroxi vitamina D Policy Brief

Author

Herrera Méndez, Emiliano Mauricio, primary, Yomayusa González, Nancy, additional, Low Padilla, Eduardo, additional, Oliveros Velásquez, Juan David, additional, Mendivelso Duarte, Fredy, additional, Gómez Gómez, Olga Victoria, additional, Castillo Gutiérrez, Ana María, additional, Barrero Garzón, Liliana Isabel, additional, Álvarez Moreno, Carlos Arturo, additional, Moscoso Martínez, Ernesto Augusto, additional, Ruíz Blanco, Pilar Cristina, additional, Luna Ríos, Joaquín Gustavo, additional, Ortiz, Natasha, additional, Herrera, Emilio Mauricio, additional, Guevara Santamaria, Fabian Ricardo, additional, Moreno Gómez, Jairo Enrique, additional, Cárdenas Ramírez, Héctor Mauricio, additional, González González, Camilo Alberto, additional, Jannauth, María José, additional, Patiño Pérez, Adulkarin, additional, Pinto, Diego Alejandro, additional, Acevedo, Juan Ramón, additional, Torres Serrano, Rodolfo Eduardo, additional, Montero Cetina, Jairo Camilo, additional, Acevedo Velasco, Andrés David, additional, Cáceres, Ximena Adriana, additional, Olmos, Jairo Acuña, additional, Arias, Carlos Andrés, additional, Rozo, José Medardo, additional, Castellanos Parada, Jeffrey, additional, López Miranda, Ángelo Mauricio, additional, Pinzón Serrano, Estefanía, additional, Rincón Sierra, Oswaldo, additional, Isaza Ruget, Mario, additional, Suárez Ramos, María del Pilar, additional, Vargas Rodríguez, Johanna, additional, Mejia Gaviria, Natalia, additional, Moreno Marín, Sandra Yadira, additional, García Guarín, Bibiana María, additional, Cárdenas, Martha Lucía, additional, Chavarro, Luis Fernando, additional, Ronderos Bernal, Camila, additional, Rico Landazabal, Arturo, additional, Rosero Olarte, Francisco Oscar Fernando, additional, Medina Orjuela, Adriana, additional, Alfaro Tejeda, Mercedes Teresa, additional, Coronado Daza, Jorge Antonio, additional, Yama Mosquera, Erica, additional, Hernández Sierra, Astrid Patricia, additional, Restrepo Valencia, César Augusto, additional, Álvarez, Javier Arango, additional, Baquero Rodríguez, Richard, additional, Robayo García, Adriana, additional, Carballo Zarate, Virgil, additional, Rodríguez Sánchez, Martha Patricia, additional, Bernal, Dora P., additional, Jaramillo, Laura, additional, Mejía Gaviria, Natalia, additional, and Aroca, Gustavo, additional

Published
2019
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20. Pielonefritis xantogranulomatosa en pediatría

Author

Álvarez Cuartas, Stepffania, Muñoz Echeverri, María Carolina, Arias Restrepo, Luis Fernando, Baquero Rodríguez, Richard, Álvarez Cuartas, Stepffania, Muñoz Echeverri, María Carolina, Arias Restrepo, Luis Fernando, and Baquero Rodríguez, Richard

Abstract

Xanthogranulomatous pyelonephritis is an atypical, severe and infrequent variant of a chronic form of pyelonephritis, which can occur at any age. In children it is generally associated with congenital urological malformations as obstruction of the urinary tract. Next, we describe the case of a 1-year-old patient, with recurrent febrile episodes, where after the failed treatment of pionefrosis and after ruling out multiple differential diagnoses, it was decided to perform a left nephrectomy clinically considering a xanthogranulomatous pyelonephritis, a diagnosis confirmed by study histopathological., La pielonefritis xantogranulomatosa es una variante atípica, severa y poco frecuente de una forma crónica de pielonefritis, que puede ocurrir a cualquier edad. En niños está generalmente asociada a malformaciones urológicas congénitas como obstrucción de las vías urinarias. Se describe el caso de un paciente de un año con episodios febriles recurrentes en quien, tras el tratamiento fallido de una pionefrosis y después de descartar múltiples diagnósticos diferenciales, se decide realizar nefreureterectomía izquierda, considerando clínicamente una pielonefritis xantogranulomatosa, la cual fue confirmada por estudio histopatológico.

Published
2018

21. Uso de rituximab en pacientes pediátricos con síndrome nefrótico córtico-resistente. Experiencia de un centro

Author

Serna-Higuita, Lina María, primary, Vanegas-Ruiz, Juan José, additional, Serrano-Gayubo, Ana Katherina, additional, Vélez-Echeverri, Catalina, additional, Ochoa-García, Carolina Lucía, additional, Rojas-Rosas, Luisa Fernanda, additional, Baquero-Rodríguez, Richard, additional, Nieto-Ríos, John Fredy, additional, Ocampo-Kohn, Catalina, additional, Aristizábal-Alzate, Arbey, additional, Orozco-Forero, Juan Pablo, additional, Flórez, Jesús Antonio, additional, Zuleta-Tobón, Jhon Jairo, additional, and Zuluaga-Valencia, Gustavo Adolfo, additional

Published
2014
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22. Recomendaciones sobre la vacunación contra SARS-CoV-2 en pacientes en diálisis y lista de espera de trasplante renal

Author

Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Nefrología, Gonzalez Gonzalez, Camilo Alberto, Rodriguez Sanchez, Martha Patricia, Yomayusa González, Nancy, Yama, Erica, Aroca Martínez, Gustavo, Chacón Acevedo, Kelly Rocío, Robayo, Adriana, Baquero Rodríguez, Richard, Montero, Camilo, Torres Serrano, Rodolfo Eduardo, Restrepo, Cesar, Benavidez, Carlos, Coronado Daza, Jorge Antonio, Castelo Meza, Sandra, Ariza García, Amaury Miguel, Mercado, Álvaro, Ballesteros, David Andrés, Muñoz, Germán, Guerrero Tinoco, Gustavo Adolfo, Zapata Chica, Carlos Andrés, Carrascal Guzmán, Martha Isabel, Mejía, Natalia, Rico Fontalvo, Jorge Eduardo, Ramírez Marmolejo, Roberto, Vargas, Juan Guillermo, Acevedo Velasco, Andrés David, Pérez, Jorge, Gayón, Diana, Borraez Ramos, Deisy Mayerleth, Larrarte Arenas, Carolina, Ferreiro-Fuentes, Alejandro, Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Nefrología, Gonzalez Gonzalez, Camilo Alberto, Rodriguez Sanchez, Martha Patricia, Yomayusa González, Nancy, Yama, Erica, Aroca Martínez, Gustavo, Chacón Acevedo, Kelly Rocío, Robayo, Adriana, Baquero Rodríguez, Richard, Montero, Camilo, Torres Serrano, Rodolfo Eduardo, Restrepo, Cesar, Benavidez, Carlos, Coronado Daza, Jorge Antonio, Castelo Meza, Sandra, Ariza García, Amaury Miguel, Mercado, Álvaro, Ballesteros, David Andrés, Muñoz, Germán, Guerrero Tinoco, Gustavo Adolfo, Zapata Chica, Carlos Andrés, Carrascal Guzmán, Martha Isabel, Mejía, Natalia, Rico Fontalvo, Jorge Eduardo, Ramírez Marmolejo, Roberto, Vargas, Juan Guillermo, Acevedo Velasco, Andrés David, Pérez, Jorge, Gayón, Diana, Borraez Ramos, Deisy Mayerleth, Larrarte Arenas, Carolina, and Ferreiro-Fuentes, Alejandro

Abstract

Contexto: las personas con diálisis se consideran una población de alto riesgo de infección porSARS-CoV-2, complicaciones y muerte. En Colombia, cerca del 44 % de la población en diálisis es menor de 60 años, adicionalmente, por los mismos retos que ha impuesto la pandemia a los programas de trasplantes, se ha incrementado notoriamente la población joven que debe seguir en diálisis al no tener opción a corto plazo de un trasplante renal, por lo tanto, las limitaciones en el acceso temprano a la vacunación contra SARS-CoV-2 agudizarían los problemas de esta población, provocando pérdidas considerables en años de vida que la vacuna podría salvar. Objetivo: el objetivo del presente documento es sintetizar los principales motivos por los que se recomienda la priorización de la vacunación de los pacientes en diálisis crónica y lista de espera para trasplante renal. Metodología :se realizó una búsqueda rápida de información sobre la vacunación en pacientes con ERC en diálisis o en espera de trasplante renal. La información resultante fue analizada críticamente por expertos en nefrología para la formulación de recomendaciones. Los resultados dela búsqueda se presentan a manera de síntesis narrativa. Resultados: a partir de la información revisada y discutida por los expertos en nefrología se proponen 4 recomendaciones para la vacunación contra el virus SARS-Cov-2. Conclusiones: la Asociación Colombiana de Nefrología e Hipertensión Arterial, la Asociación Colombiana de Nefrología Pediátrica y la Asociación Colombiana de Trasplante de Órganos, comprometidos con la salud de los pacientes con enfermedad renal en diálisis y listas de espera de trasplantes en Colombia, se unen a la solicitud mundial de generar recomendaciones para la vacunación contra SARS-CoV-2.

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