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1. Yield of genetic association signals from genomes, exomes and imputation in the UK Biobank

2. Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone

3. Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis.

4. NOTCH3 p.Arg1231Cys is markedly enriched in South Asians and associated with stroke

5. Genetic risk factors for COVID-19 and influenza are largely distinct

6. A deep catalogue of protein-coding variation in 983,578 individuals

7. Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes

8. Author Correction: A deep catalogue of protein-coding variation in 983,578 individuals

10. A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

11. Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

12. Genotyping, sequencing and analysis of 140,000 adults from Mexico City

13. Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects

14. Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis

15. Rare coding variants in CHRNB2 reduce the likelihood of smoking

16. A large meta-analysis identifies genes associated with anterior uveitis

17. Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity

18. Common and rare variant associations with clonal haematopoiesis phenotypes

19. Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

20. Author Correction: Genotyping, sequencing and analysis of 140,000 adults from Mexico City

21. Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility

22. Pharmacologic and Genetic Downregulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Survival From Sepsis

23. Large-scale genome-wide association study of coronary artery disease in genetically diverse populations

24. Whole-genome sequencing reveals host factors underlying critical COVID-19

25. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

26. Mucus sialylation determines intestinal host-commensal homeostasis

27. Performance of polygenic risk scores for cancer prediction in a racially diverse academic biobank

30. Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease

31. ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma

32. Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes

33. Population-scale analysis of common and rare genetic variation associated with hearing loss in adults

34. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

35. “PMS2CL interference leading to erroneous identification of a pathogenic PMS2 variant in Black Patients”

36. The power of genetic diversity in genome-wide association studies of lipids

37. Genetic Susceptibility to Mood Disorders and Risk of Stroke: A Polygenic Risk Score and Mendelian Randomization Study

38. SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues

39. Safety and efficacy of itepekimab in patients with moderate-to-severe COPD: a genetic association study and randomised, double-blind, phase 2a trial

40. The genetic architecture of Plakophilin 2 cardiomyopathy

41. Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

42. An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs

43. Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

44. Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

45. Exome sequencing and analysis of 454,787 UK Biobank participants

46. Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

47. Biallelic BRCA Loss and Homologous Recombination Deficiency in Nonbreast/Ovarian Tumors in Germline BRCA1/2 Carriers

48. Polygenic Risk of Psychiatric Disorders Exhibits Cross-trait Associations in Electronic Health Record Data From European Ancestry Individuals

49. Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank

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