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2. Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial

Author

Abbasciano, Isabella, Abrantes, Catarina, Accarino, Simone, Adler, Sharon, Adoberg, Annika, Afsari, Rouzbeh, Ahmad, Syeda, Ahmed, Jafar, Ahn, Wooin, Ajayi, Bamidele, Aksamit, Dariusz, Al Chalabi, Saif, Alamartine, Eric, Alchi, Bassam, Ali, Mohammad, Aliotta, Roberta, Almaani, Salem, Almeida, Catarina, Almeida, Edgar, Alvarez, Francisco de la Prada, Alves, Patricia, Annese, Francesca, Appel, Gerald, Arduan, Alberto Ortiz, Arena, Maria, Arevalo, Marta Calvo, Arfaania, Dariush, Arias, Carlos, Aristoy, Emma Calatayud, Asakiene, Egle, Ashley, Sarah, Assefi, Ali, Atenza, Alba, Auerbach, Asta, Augustyniak-Bartosik, Hanna, Avella, Monroy, Ayling-Smith, Jonathan, Ayoub, Isabelle, Ayvazyan, Christine, Baccaro, Rocco, Bailey, Asha, Baker, Bruce, Balamuthusamy, Saravanan, Ballarin, Jose, Barata, Rui, Barbic, Jerko, Barisic, Dunja, Barratt, Jonathan, Barreto, Jose Carlos de Jesus, Barrios, Clara, Belingheri, Mirco, Benesova, Anna, Bernabeu, Ana Avila, Bernhardt, Wanja, Bhadra, Shamik, Biancone, Luigi, Blanchard, Anne, Boaglio, Elena, Bolignano, Davide, Bomback, Andrew, Bonilla, Gustavo Andres Useche, Bordoli, Monica, Bose, Bhadran, Boudville, Neil, Brandon, Donald, Brown, Karen, Broyet, Christian, Bucknall, Thomas, Buffet, Alexandre, Bumblyte', Inga Arune, Burdese, Manuel, Burgos, Natalia Allende, Burguet, Laure, Burtey, Stephane, Busch, Martin, Cakiroglu, Figen, Campbell, Victoria, Canetta, Pietro, Capaccio, Flavia, Carbonell, Juan, Cardoso, Filipa, Carro, Clara Garcia, Carroll, Robert, Carron, Pierre-Louis, Carullo, Nazareno, Cassia, Matthias, Caster, Dawn, Castillo, Belen Vizcaino, Catucci, Davide, Cavalli, Andrea, Chae, Dong-Wan, Chakera, Aron, Chan, Doris, Chan, Gary Chi Wang, Chan, Anthony Ting Pong, Chan, Lai Wan, Chang, Jae Hyun, Chang, Ming-Shan, Chapman, Fiona, Charytan, Chaim, Chaudhry, Asghar, Cheetham, Melissa, Chen, Cheng-Hsu, Chen, Hsin-Yu, Chen, Chien-Liang, Chen, Hung-Yuan, Chen, Hung-Chun, Chenine, Leila, Cheung, Siu Fai, Cheung, Chee Kay, Chiche-Jourde, Noemie, Chiu, Hsien-Fu, Chiu, Yen-Ling, Chiu, Yi-Wen, Chiu, Ian, Choi, Hoon Young, Chou, Kang-Ju, Chowdhury, Paramit, Chowdhury, Pradip, Chrysochou, Constantina, Chukwu, Chukwuma, Chun, Ka Yeong, Chung, Wookyung, Cieniawski, Dominik, Claisse, Guillaume, Clayton, Philip, Cleary, Catalina Martín, Clement, Nisha, Coates, Toby, Cogno, Chiara, Colla, Loredana, Collins, Michael, Colucci, Marco, Combe, Christian, Comi, Nicolino, Comunale, Roderick, Contreras, Gabriel, Cooper, Bruce, Coppock, Gaia, Costa, Ana Cortesão, Costanzi, Stefano, Cozzolino, Mario, Crail, Susan, Cunha, Liliana, Curry, Elizabeth, Dai, Tiane, Daina, Erica, Daneshvari, Sam, Dasgupta, Indranil, DaSilva, Louise, Davidson, Robert, De Bhailis, Aine Maire, de Précigout, Valérie, Decupere, Marc, Delmas, Yahsou, Deodato, Francesca, Dhaun, Neeraj, Dhaygude, Ajay, Dhelaria, Ranjit, Di Maio, Federica, Diezhandino, Maria Angeles Goicoechea, Dika, Zivka, Dinic, Miriana, Dittmer, Ian, Dobre, Mirela, Doctor, Gabriel, Donati, Gabriele, Doubel, Peter, Douthit, Nicole, Draganova, Diliana, Drexler, Yelena, Drinkovic, Martin, Drinovska, Klara, Dudreuilh, Caroline, Dumond, Clement, Durlen, Ivan, Dussol, Bertrand, Encarnacion, Montserrat Diaz, Endre, Zoltan, Enrique, Jorge, Eqbal, Yusuf, Erlich, Jonathan, Esposito, Vittoria, Esposito, Ciro, Fakih, Faisal, Fang, Hua-Chang, Farinha, Ana, Fearday, Aaron, Felgueiras, Joana de Sousa Soares, Felicjanczuk, Elzbieta, Fernandes, João Carlos, Fernandes, Sara, Fernandes, Adriana, Fernandez, Jose Luño, Fernandez, Victor, Fernando, Mangalee, Figueiredo, Ana Carolina, Firre, Eric, Floege, Jürgen, Flossmann, Oliver, Floyd, Lauren, Fonseca, Nuno, Fonseca, Jose Nuno de Almeida Agapito, Foote, Celine, Forbes, Suzanne, Forcen, Angel, Fornoni, Alessia, Fouassier, David, Fraser, Ian, Fung, Ka Shun Samuel, Furlano, Monica, Furtado, Teresa, Gadh, Rajdeep, Gaisset, Roxane, Gallagher, Martin, Gameiro, Joana, Gangadharan, Muralikrishna, Garcia, Fabiola Alonso, Garcia, Olga Gracia, Garg, Gunjan, Garrouste, Cyril, Gautam, Archana, Geara, Abdallah, Geddes, Colin, Gellineo, Lana, Germain, Michael, Gesualdo, Loreto, Ghalli, Farid, Giaroni, Francesco, Giles, Harold, Gillies, Alastair, Gimeno, Ana Vilar, Girardet, Annette, Glaze, Jeffrey, Goh, Tze, Gois, Mario, Goldsmith, Christopher, Goma, Elena, Gomes, Ana Marta, Goncalves, Luis Pedro Falcao, Goncalves, Sara, Gontarek-Kacprzak, Julita, Gonzalez, Carlos, Gopu, Arun, Gowda, Nayan, Gray, Nicholas, Greco, Barbara, Green, Heather, Greze, Clarisse, Griffin, Sian, Guldris, Secundino Cigarran, Guzman, Ursula Verdalles, Ha, Jeffrey Tsun Kit, Hall, Amanda, Hamilton, Patrick, Han, Seung Hyeok, Haws, Robert, Hayat, Ashik, Heath, Lauren, Heinrichs, Sven, Henderson, Andrew, Henderson, Amy, Hendren, Elizabeth, Heng, Anne-Elisabeth, Heres, Salia Virxinia Pol, Herfurth, Johann Konstantin, Herrero, Evangelina Merida, Ho, Tzung-Yo, Hogan, Jonathan, Hohenstein, Bernd, Hollett, Peter, Horvatic, Ivica, Hsu, Bang-Gee, Hsu, Chia-Tien, Hsu, Chih-Yang, Hsu, Shih-Ping, Huang, Chien-Wei, Hudson, Amy, Hung, Chi-Chih, Hwang, Shang-Jyh, Hwang, Daw-Yang, Hyun, Young Youl, Ilmoja, Madis, Irish, Georgina, Jacob, Radu, Jahan, Sadia, Jain, Arunima, Jamar, Sofie, Jander, Anna, Jang, Hye Ryoun, Janko, Catherine, Jardine, Meg, Jaskowski, Piotr, Jeantet, Guillaume, Jelakovic, Bojan, Jeon, Junseok, Jeong, Jong Cheol, Jesudason, Shilpanjali, Jittirat, Arksarapuk, Jo, Sang-Kyung, Jones, Rachel, Joo, Narae, Jorge, Sofia, Julian, Bruce, Jung, JiYong, Jyothinagaram, Praveena, Kadakia, Jigar, Kamal, Fahameedah, Kanigicherla, Durga, Karanovic, Sandra, Karras, Alexandre, Kasimatis, Theodoros, Kassem, Mohamad, Kattamanchi, Siddhartha, Keller, Christopher, Kentric, Dubravka Trajbar, Kettner, Christiane, Khalil, Kassem, Kim, Dana, Kim, Se Joong, Kim, Yeong Hoon, Kim, Yunmi, Kim, Hyung Wook, Kim, Sunggyun, Kim, Jwa-Kyung, Kim, Aejin, Kim, Myung-Gyu, Kimber, Cassandra, Klamm, Kathryn, Koch, Annegret, Koester, Eric, Kolvald, Kulli, Kon, Sui, Kooienga, Laura Ann, Kotwal, Sradha, Krajewska, Magdalena, Kratka, Karolina, Krishnan, Anoushka, Krishnasamy, Rathika, Krueger, Thilo, Kruljac, Ivan, Kulka, Simone, Kunzendorf, Ulrich, Kuo, Mei-Chuan, Kuo, Hung-Tien, Kuo, Sheng, Kwan, Lorraine Pui Yuen, Kwella, Norbert, Kwella, Bogna, Kyaw, Kay, Labat, Aurore, Lafayette, Richard, Lagatta, Mark, Lam, Chi Kwan Darwin, Lambie, Mark, Lanaret, Camille, Latif, Farah, Laute, Margo, Law, Wai Ping, Lawman, Sarah, Lazo, Mercedes Salgueira, Lee, Hajeong, Lee, Moon Hyoung, Lee, Kyu-Beck, Lee, Hyung-seok, Lee, JungEun, Lee, Hyun Hee, Lee, Po-Tsang, Leis, Liisi, Lemahieu, Wim, Leung, Janson, Li, Yan, Lie, Davina Ngoi Wah, Lifland, Howard, Lilienthal, Kadri, Lim, Wai, Limardo, Monica, Livrozet, Marine, Longhi, Selena, Lopes, Daniela, Lopes, Jose Antonio, Lorde, Nathan, Luxton, Grant, Ma, Mingyao, Madhrira, Machaiah, Madonia, Phillip, Maes, Bart, Mahadevan, Kumaradevan, Mahdi, Amar, Mahdi, Eamon, Maillard, Nicolas, Maixnerova, Dita, Majstorovic Barac, Karolina, Malecki, Robert, Malfait, Thomas, Malvica, Silvia, Mandayam, Sreedhar, Manley, Paul, Mansfield, Nick, Marcantoni, Carmelita, Mariat, Christophe, Marin, Tamara Malek, Marin, Lida Maria Rodas, Mark, Patrick, Marques, Joana, Martinez, Eduardo Gutierrez, Martinez, Stacy, Masset, Catherine, Masson, Ingrid, Mather, Amanda, Maung Myint, Thida Maung, Mayet, Valentin, McCafferty, Kieran, McCarthy, Ellen, McDonald, Stephen, McGreal, Kerri, McMahon, Kellyn, McNally, Andrew, McQuarrie, Emily, Medina, Allyson, Meeus, Gert, Mehta, Kshama, Mendoza, Elder, Menezes, Maria, Meng, Jerry, Messa, Piergiorgio, Messias, Ana, Miarka, Przemyslaw, Miglinas, Marius, Mikacic, Ivana, Mikhail, Ashraf, Milicevic, Martina, Minasian, Raffi, Moeller, Marcus, Mohey, Hesham, Mojarrab, Javad, Mok, Maggie Ming Yee, Moncasi, Eduardo Parra, Moonen, Martial, Morales, Wenceslao Adrian Aguilera, Moreno, Eduardo Verde, Moreno, Antolina, Morris, Adam, Moutzouris, Dimitrios, Moya, Mercedes Gonzalez, Mucha, Simon, Musolino, Michela, Napodano, Pietro, Natario, Ana, Negrea, Lavinia, Nelson, Bradley, Neuen, Brendon, Newsome, Britt, Ng, Kit Chung Jack, Nguyen, Thu, Nguyen, Viet, Nicolo, Clementine, Nitschke, Martin, Noble, Euan, Nolasco, Fernando, O'Lone, Emma, Ochoa, Adriana Sierra, Oh, Kook-Hwan, Oh, SeWon, Okoh, Pedro, Ombelet, Sara, O'Shaughnessy, Michelle, Ou, Shih-Hsiang, Packham, David, Padiyar, Aparna, Pai, Mei-Fen, Pamplona, Irene Agraz, Pan, Szu-Yu, Pandya, Bhavna, Papadia, Federica, Pardinhas, Clara, Parikh, Nishita, Parikh, Samir, Park, Hyeong Cheon, Park, Jung Tak, Parreira, Lucia, Passerini, Patrizia, Patak, Ramachandra, Patecki, Margret, Patel, Rajan, Patel, Jusmin, Patel Suthar, Meera, Patella, Gemma, Patrikyan, Artashes, Pavlovic, Drasko, Paxton, William, Peh, Chen, Peleg, Yonatan, Pelicano, Josep Miquel Blasco, Peng, Yu-Sen, Pereira de Vicente, Manuel, Perez, Jonay Pantoja, Perez, Erika, Perez de Jose, Ana, Pérez Gómez, María Vanessa, Perez Lluna, Leticia, Peri, Usha, Perico, Norberto, Philipponnet, Carole, Phua, Elaine, Piel, Julia, Pillai, Unnikrishnan, Pilmore, Helen, Plavljanic, Djuro, Plaza, Mercedes Velo, Pollock, Carol, Ponnusamy, Arvind, Ponti, Serena, Powell, Thomas, Pradhan, Nishigandha, Prado, Raul Fernandez, Prkacin, Ingrid, Pruthi, Rishi, Pugh, Dan, Quinn, Sarah, Quintana, Luis F, Raakesh, Lathika, Rabindranath, Kannaiyan, Radermacher, Luc, Radhakrishnan, Jai, Ragy, Omar Sherin Ibrahim, Raichoudhury, Ritesh, Raimundo, Mario, Randone, Paolo, Razavian, Mona, Reichel, Helmut, Reis, Marina, Remuzzi, Giuseppe, Reynolds, Annie, Ricchiuto, Anna, Rico, Ivon Maritza Bobadilla, Rigothier, Claire, Ritchie, Angus, Rivero, Maria Antonieta Azancot, Rizk, Dana, Ro, Han, Rodriguez, Alfred, Rodriguez Garcia, Eva, Roger, Simon, Rony, Mohammad, Rosenberg, Mai, Roueff, Stephane, Rovin, Brad, Roxburgh, Sarah, Ruiz, Mario, Rusinol, Helena Marco, Rychlik, Ivan, Sá, Helena, Salehi, Tania, Sánchez de la Nieta, Maria Dolores, Sanden, Silja, Santockiene, Lina, Santos, Patricia Valerio, Santos, Iara Da Silva, Sargsyan, Mari, Sarnow, Franziska, Sat, Sebahat, Satora, Ewa, Savuk, Ana, Sayer, Matthew, Schlieper, Georg, Schlosser, Mandy, Schmidt-Guertler, Hans, Schockaert, Olivier, Schulte, Kevin, Schulz, Lisa, Selvaskandan, Haresh, Semple, David, Sen, Shaundeep, Seppet, Elviira, Serrano, Antonio Galan, Serre, Jean-Emmanuel, Sevillano, Angel, Shah, Sapna, Shen, Yvonne, Sheridan, Brittany, Shu, Kai-Hsiang, Sightler, Ford, Silva, Sónia, Silva, Arnold, Sinha, Smeeta, Siriwardana, Amanda, Sitas, Zvonimir, Sivo, Carmen, Sizeland, Peter, Sly, Cathylee, Smith, Priscilla, Snow, Brian, Soares, Elsa Sofia Quadrado, Solazzo, Andrea, Solis, Elena Gutierrez, Solomon, Laurence, Song, Young Rim, Sousa, Helena, Spinowitz, Bruce, Stallworthy, Elizabeth, Stamellou, Eleni, Stanczyk, Malgorzata, Stangenberg, Stefanie, Stankovic, Marija, Stankuviene, Asta, Stea, Emma Diletta, Stompor, Tomasz, Storrar, Joshua, Sullivan, James, Sulowicz, Wladyslaw, Suyumova, Irina, Szeto, Cheuk Chun, Tamarit, Esther, Tan, Eddie, Tan, May, Tang, Sydney Chi Wai, Tang, Hon, Teixeira, Catarina, Telling, Kadri, Terrades, Natalia Ramos, Tesar, Vladimir, Tez, Didem, Thervet, Eric, Thibaudin, Damien, Thomas, Mark, Thyagarajan, Nikhil, Tkaczyk, Marcin, Torreggiani, Massimo, Trillini, Matias, Tsai, Shang-Feng, Tsai, Wan-Chuan, Tsai, Jer-Chia, Tseng, Po-Yu, Tumlin, James, Tung, Kuei-Ting, Turnbull, Angus, Udani, Suneel, Uhlinova, Jana, Unt, Kristin, Urciuolo, Federica, Vanacker, An, Vandewiele, Bert, Vaz, Alvaro, Veermae, Kristi, Viaene, Liesbeth, Vickiene, Alvita, Vigano, Sara, Vila, Maria Antonia Munar, Vilayur, Eswari, Villanueva, Caridad Martinez, Villarroya, Cristina Medrano, Villen, Alejandro Soria, Viramontes, Veronica, Vita, Caterina, Vujcic, Dunja, Wahba, Mona, Wan, Susan, Wang, Chih-Hsien, Warling, Xavier, Waters, Gerald, Waugh, Jane, Weiland, Lea, Weiner, Stefan, Weinreich, Thomas, Werth, Stephan Christian, Wickens, Olivia, Wijeratne, Vidu, Wilder, Karen, Willcocks, Lisa, Williams, Allister, Winiarska, Agata, Wirtz, Nikolaus, Wolf, Lothar, Wolf, Gunter, Wong, Muh Geot, Wong, Yick Hei, Wong, Sze Ho Sunny, Workeneh, Biruh, Wu, Ming-Ju, Wu, Hon-Yen, Wyndham, Roger, Yang, Jihyun, Yang, Ju-Yeh, Yeap, Chii, Yim, Ka Fai, Yong, Kenneth, Yoo, Tae-Hyun, Yoon, Songuk, Yu, Tung-Min, Yue, Tak Tai Andrew, Zakari, Michel, Zakauskiene, Urte, Zaoui, Philippe, Zbrzezniak, Justyna, Zielinska, Dorota, Zizzi, Carlotta Federica, Rovin, Brad H, Heerspink, Hiddo J L, Alpers, Charles E, Bieler, Stewart, Diva, Ulysses A, Inrig, Jula K, Kohan, Donald E, Komers, Radko, Małecki, Robert, Mercer, Alex, Noronha, Irene L, Oh, Se Won, Peh, Chen Au, Praga, Manuel, Preciado, Priscila, Rheault, Michelle N, Rote, William E, Tang, Sydney C W, Trachtman, Howard, Trimarchi, Hernán, Tumlin, James A, and Perkovic, Vlado

Published
2023
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3. Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial

Author

Alarmartine, Eric, Barratt, Jonathan, Chae, Dong Wan, Del Vecchio, Lucia, Floege, Jurgen, Hwang, Shang-Jyh, Jelakovic, Bojan, Maes, Bart, Malecki, Robert, Miglinas, Marius, Nolasco, Fernando Eduardo Barbosa, Praga, Manual, Rabindranath, Kannaiyan, Rosenberg, Mai, Rovin, Brad, Tang, Sydney Chi Wai, Tesar, Vladmir, Wong, Muh Geot, Bose, Bhadran, Gangadharan, Muralikrishna, McDonald, Stephen, Peh, Chen, Jahan, Sadia, Yeap, Chii, Clayton, Philip, Irish, Georgina, Thyagarajan, Nikhil, Hollett, Peter, Krishnasamy, Rathika, Carroll, Robert, Jesudason, Shilpanjali, Crail, Susan, Coates, Toby, Waugh, Jane, Noble, Euan, Mahadevan, Kumaradevan, Campbell, Victoria, Salehi, Tania, Lim, Wai, Boudville, Neil, Chakera, Aron, Chan, Doris, Krishnan, Anoushka, Eqbal, Yusuf, Gillies, Alastair, Vilayur, Eswari, Maung Myint, Thida Maung, Gray, Nicholas, Cheetham, Melissa, Pollock, Carol, Cooper, Bruce, Mather, Amanda, Roxburgh, Sarah, Shen, Yvonne, Stangenberg, Stefanie, Siriwardana, Amanda, O'Lone, Emma, Wan, Susan, Neuen, Brendon, Tsun Kit Ha, Jeffrey, Kim, Dana, Heath, Lauren, Jain, Arunima, Phua, Elaine, Li, Yan, Gallagher, Martin, Jardine, Meg, Ritchie, Angus, Razavian, Mona, Foote, Celine, Wyndham, Roger, Sen, Shaundeep, Endre, Zoltan, Erlich, Jonathan, Fernando, Mangalee, Yong, Kenneth, Luxton, Grant, Kotwal, Sradha, Roger, Simon, Wijeratne, Vidu, Packham, David, Fraser, Ian, Vandewiele, Bert, Laute, Margo, Lemahieu, Wim, Jamar, Sofie, Ombelet, Sara, Meeus, Gert, Decupere, Marc, Schockaert, Olivier, Doubel, Peter, Viaene, Liesbeth, Radermacher, Luc, Masset, Catherine, Moonen, Martial, Firre, Eric, Milicevic, Martina, Warling, Xavier, Vanacker, An, Malfait, Thomas, Durlen, Ivan, Horvatic, Ivica, Savuk, Ana, Gellineo, Lana, Karanovic, Sandra, Dika, Zivka, Plavljanic, Djuro, Mikacic, Ivana, Trajbar Kentric, Dubravka, Barisic, Dunja, Stankovic, Marija, Majstorovic Barac, Karolina, Kruljac, Ivan, Pavlovic, Drasko, Drinkovic, Martin, Prkacin, Ingrid, Barbic, Jerko, Sitas, Zvonimir, Vujcic, Dunja, Rychlik, Ivan, Benesova, Anna, Drinovska, Klara, Kratka, Karolina, Maixnerova, Dita, Ilmoja, Madis, Unt, Kristin, Lilienthal, Kadri, Auerbach, Asta, Leis, Liisi, Piel, Julia, Adoberg, Annika, Kolvald, Kulli, Veermae, Kristi, Telling, Kadri, Seppet, Elviira, Uhlinova, Jana, Zaoui, Philippe, Carron, Pierre-Louis, Masson, Ingrid, Dinic, Miriana, Thibaudin, Damien, Broyet, Christian, Maillard, Nicolas, Mohey, Hesham, Mariat, Christophe, Claisse, Guillaume, Alamartine, Eric, Dussol, Bertrand, Burtey, Stephane, Chiche-Jourde, Noemie, Serre, Jean-Emmanuel, Jeantet, Guillaume, Chenine, Leila, Blanchard, Anne, Roueff, Stephane, Thervet, Eric, Fouassier, David, Buffet, Alexandre, Livrozet, Marine, Gaisset, Roxane, Karras, Alexandre, Heng, Anne-Elisabeth, Garrouste, Cyril, Philipponnet, Carole, Nicolo, Clementine, Atenza, Alba, Lanaret, Camille, Greze, Clarisse, Mayet, Valentin, Dumond, Clement, Delmas, Yahsou, Combe, Christian, Rigothier, Claire, Burguet, Laure, Labat, Aurore, Mucha, Simon, de Précigout, Valérie, Weinreich, Thomas, Reichel, Helmut, Draganova, Diliana, Wolf, Lothar, Hohenstein, Bernd, Heinrichs, Sven, Kulka, Simone, Sat, Sebahat, Weiland, Lea, Krueger, Thilo, Wolf, Gunter, Kettner, Christiane, Schlosser, Mandy, Herfurth, Johann Konstantin, Koch, Annegret, Busch, Martin, Werth, Stephan Christian, Nitschke, Martin, Cakiroglu, Figen, Sarnow, Franziska, Schulz, Lisa, Weiner, Stefan, Wirtz, Nikolaus, Koester, Eric, Moeller, Marcus, Stamellou, Eleni, Sanden, Silja, Schmidt-Guertler, Hans, Bernhardt, Wanja, Patecki, Margret, Schlieper, Georg, Schulte, Kevin, Girardet, Annette, Kunzendorf, Ulrich, Kwan, Lorraine Pui Yuen, Mok, Maggie Ming Yee, Chan, Gary Chi Wang, Ma, Mingyao, Lie, Davina Ngoi Wah, Chan, Anthony Ting Pong, Szeto, Cheuk Chun, Ng, Kit Chung Jack, Cheung, Siu Fai, Yue, Tak Tai Andrew, Fung, Ka Shun Samuel, Tang, Hon, Yim, Ka Fai, Law, Wai Ping, Wong, Yick Hei, Lam, Chi Kwan Darwin, Wong, Sze Ho Sunny, Marcantoni, Carmelita, Aliotta, Roberta, Deodato, Francesca, Patella, Gemma, Comi, Nicolino, Vita, Caterina, Carullo, Nazareno, Bolignano, Davide, Musolino, Michela, Trillini, Matias, Perico, Norberto, Remuzzi, Giuseppe, Daina, Erica, Biancone, Luigi, Colla, Loredana, Burdese, Manuel, Cogno, Chiara, Boaglio, Elena, Abbasciano, Isabella, Zizzi, Carlotta Federica, Randone, Paolo, Napodano, Pietro, Ricchiuto, Anna, Cassia, Matthias, Accarino, Simone, Cozzolino, Mario, Baccaro, Rocco, Costanzi, Stefano, Di Maio, Federica, Arena, Maria, Urciuolo, Federica, Vigano, Sara, Cavalli, Andrea, Limardo, Monica, Bordoli, Monica, Ponti, Serena, Longhi, Selena, Solazzo, Andrea, Giaroni, Francesco, Donati, Gabriele, Torreggiani, Massimo, Catucci, Davide, Colucci, Marco, Esposito, Vittoria, Esposito, Ciro, Gesualdo, Loreto, Capaccio, Flavia, Diletta Stea, Emma, Sivo, Carmen, Annese, Francesca, Papadia, Federica, Messa, Piergiorgio, Belingheri, Mirco, Passerini, Patrizia, Malvica, Silvia, Vickiene, Alvita, Zakauskiene, Urte, Asakiene, Egle, Bumblyte', Inga Arune, Stankuviene, Asta, Santockiene, Lina, Hayat, Ashik, Williams, Allister, Sizeland, Peter, Tan, Eddie, Waters, Gerald, Chan, Lai Wan, Henderson, Andrew, Turnbull, Angus, McNally, Andrew, Reynolds, Annie, Pilmore, Helen, Dittmer, Ian, Manley, Paul, Stallworthy, Elizabeth, Goh, Tze, Semple, David, Collins, Michael, Curry, Elizabeth, Ahmed, Jafar, Nguyen, Thu, Winiarska, Agata, Zbrzezniak, Justyna, Stompor, Tomasz, Krajewska, Magdalena, Augustyniak-Bartosik, Hanna, Zielinska, Dorota, Jander, Anna, Stanczyk, Malgorzata, Tkaczyk, Marcin, Miarka, Przemyslaw, Aksamit, Dariusz, Jaskowski, Piotr, Sulowicz, Wladyslaw, Cieniawski, Dominik, Gontarek-Kacprzak, Julita, Felicjanczuk, Elzbieta, Kwella, Norbert, Kwella, Bogna, Satora, Ewa, Fernandes, João Carlos, Gomes, Ana Marta, Reis, Marina, Lopes, Daniela, Almeida, Catarina, Sá, Helena, Figueiredo, Ana Carolina, Pardinhas, Clara, Almeida, Edgar, Raimundo, Mario, Cortesão Costa, Ana, Falcao Goncalves, Luis Pedro, Fernandes, Sara, Silva, Sónia, Teixeira, Catarina, Fernandes, Adriana, Nolasco, Fernando, Alves, Patricia, Gois, Mario, Fonseca, Nuno, Messias, Ana, Menezes, Maria, Cardoso, Filipa, Sousa, Helena, Marques, Joana, Barata, Rui, Lopes, Jose Antonio, Jorge, Sofia, Gameiro, Joana, de Almeida Agapito Fonseca, Jose Nuno, Goncalves, Sara, Farinha, Ana, Valerio Santos, Patricia, Natario, Ana, de Jesus Barreto, Jose Carlos, Abrantes, Catarina, Quadrado Soares, Elsa Sofia, Soares Felgueiras, Joana de Sousa, Cunha, Liliana, Parreira, Lucia, Furtado, Teresa, Vaz, Alvaro, Oh, Kook-Hwan, Lee, Hajeong, Joong Kim, Se, Jeong, Jong Cheol, Hoon Kim, Yeong, Kim, Yunmi, Park, Hyeong Cheon, Choi, Hoon Young, Wook Kim, Hyung, Lee, Moon Hyoung, Yoon, Songuk, Lee, Kyu-Beck, Hyun, YoungYoul, Yoo, Tae-Hyun, Han, Seung Hyeok, Park, Jung Tak, Kim, Sunggyun, Song, Young Rim, Kim, Jwa-Kyung, Lee, Hyung-seok, Joo, Narae, Lee, JungEun, Ryoun Jang, Hye, Jeon, Junseok, Chung, Wookyung, Lee, HyunHee, Chang, Jae Hyun, Chun, Ka Yeong, Jung, Ji Yong, Ro, Han, Kim, Aejin, Jo, Sang-Kyung, Yang, Jihyun, Kim, Myung-Gyu, Oh, SeWon, Martinez Villanueva, Caridad, Gimeno, Ana Vilar, Andres Useche Bonilla, Gustavo, Tamarit, Esther, Galan Serrano, Antonio, Verde Moreno, Eduardo, Fernandez, Jose Luño, Goicoechea Diezhandino, Maria Angeles, Verdalles Guzman, Ursula, de Jose, Ana Perez, Ortiz Arduan, Alberto, Pérez Gómez, María Vanessa, Martín Cleary, Catalina, Prado, Raul Fernandez, Goma, Elena, Ballarin, Jose, Encarnacion, Montserrat Diaz, Da Silva Santos, Iara, Marco Rusinol, Helena, Furlano, Monica, Arias, Carlos, Barrios, Clara, Garcia, Eva Rodriguez, Sierra Ochoa, Adriana, Vizcaino Castillo, Belen, Pantoja Perez, Jonay, Gonzalez Moya, Mercedes, Sargsyan, Mari, Calatayud Aristoy, Emma, Bernabeu, Ana Avila, Perez Lluna, Leticia, Malek Marin, Tamara, Antonia Munar Vila, Maria, Bobadilla Rico, Ivon Maritza, Allende Burgos, Natalia, Gutierrez Martinez, Eduardo, Gutierrez Solis, Elena, Sevillano, Angel, Merida Herrero, Evangelina, Miquel Blasco Pelicano, Josep, Rodas Marin, Lida Maria, Quintana, Luis F, Antonieta Azancot Rivero, Maria, Ramos Terrades, Natalia, Garcia Carro, Clara, Agraz Pamplona, Irene, Salgueira Lazo, Mercedes, de la Prada Alvarez, Francisco, Alonso Garcia, Fabiola, Adrian Aguilera Morales, Wenceslao, Virxinia Pol Heres, Salia, Forcen, Angel, Parra Moncasi, Eduardo, Medrano Villarroya, Cristina, Soria Villen, Alejandro, Gracia Garcia, Olga, Velo Plaza, Mercedes, Sánchez de la Nieta, Maria Dolores, Calvo Arevalo, Marta, Moreno, Antolina, Cigarran Guldris, Secundino, de Vicente, Manuel Pereira, Munar Vila, Maria Antonia, Hsu, Bang-Gee, Wang, Chih-Hsien, Chen, Cheng-Hsu, Yu, Tung-Min, Wu, Ming-Ju, Tsai, Shang-Feng, Hsu, Chia-Tien, Chiu, Hsien-Fu, Chou, Kang-Ju, Fang, Hua-Chang, Lee, Po-Tsang, Chen, Hsin-Yu, Chen, Chien-Liang, Huang, Chien-Wei, Ou, Shih-Hsiang, Ho, Tzung-Yo, Hsu, Chih-Yang, Chang, Ming-Shan, Chiu, Yen-Ling, Peng, Yu-Sen, Shu, Kai-Hsiang, Pan, Szu-Yu, Hsu, Shih-Ping, Yang, Ju-Yeh, Pai, Mei-Fen, Tseng, Po-Yu, Wu, Hon-Yen, Tsai, Wan-Chuan, Tung, Kuei-Ting, Chen, Hung-Yuan, Chen, Hung-Chun, Kuo, Mei-Chuan, Hwang, Daw-Yang, Chiu, Yi-Wen, Hung, Chi-Chih, Kuo, Hung-Tien, Tsai, Jer-Chia, McCafferty, Kieran, Forbes, Suzanne, Dasgupta, Indranil, Thomas, Mark, Mahdi, Amar, Ajayi, Bamidele, Chowdhury, Paramit, Kasimatis, Theodoros, Moutzouris, Dimitrios, Dudreuilh, Caroline, Pruthi, Rishi, Mansfield, Nick, Doctor, Gabriel, Shah, Sapna, Kon, Sui, Smith, Priscilla, Hamilton, Patrick, Kanigicherla, Durga, Ibrahim Ragy, Omar Sherin, Alchi, Bassam, Flossmann, Oliver, Ghalli, Farid, Lawman, Sarah, Sinha, Smeeta, Chrysochou, Constantina, Chukwu, Chukwuma, Maire De Bhailis, Aine, Al Chalabi, Saif, Hudson, Amy, Gopu, Arun, Wickens, Olivia, Storrar, Joshua, Wahba, Mona, Lorde, Nathan, Rony, Mohammad, Griffin, Sian, Latif, Farah, Ali, Mohammad, DaSilva, Louise, Ayling-Smith, Jonathan, Mahdi, Eamon, Willcocks, Lisa, Jones, Rachel, Cheung, Chee Kay, Selvaskandan, Haresh, Pugh, Dan, Sayer, Matthew, Dhaun, Neeraj, Chapman, Fiona, Mark, Patrick, Geddes, Colin, McQuarrie, Emily, Patel, Rajan, Solomon, Laurence, Ponnusamy, Arvind, Morris, Adam, Okoh, Pedro, Floyd, Lauren, Dhaygude, Ajay, Leung, Janson, Goldsmith, Christopher, Pandya, Bhavna, Tez, Didem, Mikhail, Ashraf, Brown, Karen, Bucknall, Thomas, Lambie, Mark, Comunale, Roderick, Brandon, Donald, Martinez, Stacy, Hall, Amanda, Henderson, Amy, Fearday, Aaron, Douthit, Nicole, Snow, Brian, Silva, Arnold, Sly, Cathylee, Keller, Christopher, Davidson, Robert, Meng, Jerry, Haws, Robert, Kattamanchi, Siddhartha, Mojarrab, Javad, Pillai, Unnikrishnan, Lafayette, Richard, O'Shaughnessy, Michelle, Kamal, Fahameedah, Mehta, Kshama, Baker, Bruce, Ruiz, Mario, Jyothinagaram, Praveena, Peri, Usha, Paxton, William, Tumlin, James, McGreal, Kerri, McCarthy, Ellen, Kimber, Cassandra, Gautam, Archana, Khalil, Kassem, Nguyen, Viet, Minasian, Raffi, Arfaania, Dariush, Daneshvari, Sam, Zakari, Michel, Patrikyan, Artashes, Afsari, Rouzbeh, Ayvazyan, Christine, Fakih, Faisal, Lagatta, Mark, Rodriguez, Alfred, Avella, Jorge Enrique Monroy, Patak, Ramachandra, Kadakia, Jigar, Radhakrishnan, Jai, Appel, Gerald, Ahn, Wooin, Nelson, Bradley, Medina, Allyson, Ahmad, Syeda, Peleg, Yonatan, Clement, Nisha, Chiu, Ian, Hendren, Elizabeth, Bomback, Andrew, Canetta, Pietro, Spinowitz, Bruce, Charytan, Chaim, Parikh, Nishita, Kuo, Sheng, Raichoudhury, Ritesh, Dobre, Mirela, Negrea, Lavinia, Padiyar, Aparna, Jittirat, Arksarapuk, Pradhan, Nishigandha, Dhelaria, Ranjit, Balamuthusamy, Saravanan, Madhrira, Machaiah, Powell, Thomas, Lifland, Howard, Bailey, Asha, Ford Sightler, Sarah Ashley, Suthar, Meera Patel, Green, Heather, Parikh, Samir, Ayoub, Isabelle, Almaani, Salem, Contreras, Gabriel, Fornoni, Alessia, Drexler, Yelena, Geara, Abdallah, Sheridan, Brittany, Coppock, Gaia, Hogan, Jonathan, Gonzalez, Carlos, Bhadra, Shamik, Chowdhury, Pradip, Kyaw, Kay, Tan, May, Raakesh, Lathika, Mendoza, Elder, Viramontes, Veronica, Chaudhry, Asghar, Carbonell, Juan, Gadh, Rajdeep, Fernandez, Victor, Kassem, Mohamad, Jacob, Radu, Wilder, Karen, Newsome, Britt, Klamm, Kathryn, Suyumova, Irina, Kooienga, Laura Ann, Janko, Catherine, Rizk, Dana, Julian, Bruce, Caster, Dawn, Perez, Erika, Garg, Gunjan, Gowda, Nayan, Udani, Suneel, Mandayam, Sreedhar, Workeneh, Biruh, Assefi, Ali, Greco, Barbara, Germain, Michael, Patel, Jusmin, Quinn, Sarah, Sullivan, James, Glaze, Jeffrey, Madonia, Phillip, McMahon, Kellyn, Giles, Harold, Adler, Sharon, Dai, Tiane, Heerspink, Hiddo J L, Alpers, Charles E, Bieler, Stewart, Diva, Ulysses, Inrig, Jula, Komers, Radko, Mercer, Alex, Noronha, Irene L, Rheault, Michelle N, Rote, William, Trachtman, Howard, Trimarchi, Hernán, and Perkovic, Vlado

Published
2023
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4. Autosomal Dominant Polycystic Kidney Disease Inflammation Biomarkers in the Tolvaptan Era.

Author

Lapão, Tânia, Barata, Rui, Jorge, Cristina, Flores, Carlos, and Calado, Joaquim

Subjects
*PROGNOSTIC tests, *DISEASE progression, *BIOMARKERS, *INFLAMMATION
Abstract

With the approval of tolvaptan as the first specific medicine for the treatment of rapidly progressive Autosomal Dominant Polycystic Kidney Disease (ADPKD), biomarker discovery has gained renewed interest as it is widely recognized that these will be crucial in clinical decision-making, serving as either prognostic or predictive tools. Since the marketing authorization was first issued in 2015 for ADPKD, tolvaptan has remained the sole pharmacological compound specifically targeting the disease. For ADPKD patients it is an invaluable medicine for retarding disease progression. Although the field of overall biomarker discovery and validation has been detailed in several publications, the role of inflammation remains largely overlooked in ADPKD. The current work aims to provide the reader with an updated review of inflammation biomarkers research in ADPKD, highlighting the role of urinary MCP-1 (monocyte chemoattractant protein-1) as the most promising tool. [ABSTRACT FROM AUTHOR]

Published
2025
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6. Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial

Author

Rovin, Brad H, primary, Barratt, Jonathan, additional, Heerspink, Hiddo J L, additional, Alpers, Charles E, additional, Bieler, Stewart, additional, Chae, Dong-Wan, additional, Diva, Ulysses A, additional, Floege, Jürgen, additional, Gesualdo, Loreto, additional, Inrig, Jula K, additional, Kohan, Donald E, additional, Komers, Radko, additional, Kooienga, Laura Ann, additional, Lafayette, Richard, additional, Maes, Bart, additional, Małecki, Robert, additional, Mercer, Alex, additional, Noronha, Irene L, additional, Oh, Se Won, additional, Peh, Chen Au, additional, Praga, Manuel, additional, Preciado, Priscila, additional, Radhakrishnan, Jai, additional, Rheault, Michelle N, additional, Rote, William E, additional, Tang, Sydney C W, additional, Tesar, Vladimir, additional, Trachtman, Howard, additional, Trimarchi, Hernán, additional, Tumlin, James A, additional, Wong, Muh Geot, additional, Perkovic, Vlado, additional, Abbasciano, Isabella, additional, Abrantes, Catarina, additional, Accarino, Simone, additional, Adler, Sharon, additional, Adoberg, Annika, additional, Afsari, Rouzbeh, additional, Ahmad, Syeda, additional, Ahmed, Jafar, additional, Ahn, Wooin, additional, Ajayi, Bamidele, additional, Aksamit, Dariusz, additional, Al Chalabi, Saif, additional, Alamartine, Eric, additional, Alchi, Bassam, additional, Ali, Mohammad, additional, Aliotta, Roberta, additional, Almaani, Salem, additional, Almeida, Catarina, additional, Almeida, Edgar, additional, Alvarez, Francisco de la Prada, additional, Alves, Patricia, additional, Annese, Francesca, additional, Appel, Gerald, additional, Arduan, Alberto Ortiz, additional, Arena, Maria, additional, Arevalo, Marta Calvo, additional, Arfaania, Dariush, additional, Arias, Carlos, additional, Aristoy, Emma Calatayud, additional, Asakiene, Egle, additional, Ashley, Sarah, additional, Assefi, Ali, additional, Atenza, Alba, additional, Auerbach, Asta, additional, Augustyniak-Bartosik, Hanna, additional, Avella, Monroy, additional, Ayling-Smith, Jonathan, additional, Ayoub, Isabelle, additional, Ayvazyan, Christine, additional, Baccaro, Rocco, additional, Bailey, Asha, additional, Baker, Bruce, additional, Balamuthusamy, Saravanan, additional, Ballarin, Jose, additional, Barata, Rui, additional, Barbic, Jerko, additional, Barisic, Dunja, additional, Barreto, Jose Carlos de Jesus, additional, Barrios, Clara, additional, Belingheri, Mirco, additional, Benesova, Anna, additional, Bernabeu, Ana Avila, additional, Bernhardt, Wanja, additional, Bhadra, Shamik, additional, Biancone, Luigi, additional, Blanchard, Anne, additional, Boaglio, Elena, additional, Bolignano, Davide, additional, Bomback, Andrew, additional, Bonilla, Gustavo Andres Useche, additional, Bordoli, Monica, additional, Bose, Bhadran, additional, Boudville, Neil, additional, Brandon, Donald, additional, Brown, Karen, additional, Broyet, Christian, additional, Bucknall, Thomas, additional, Buffet, Alexandre, additional, Bumblyte', Inga Arune, additional, Burdese, Manuel, additional, Burgos, Natalia Allende, additional, Burguet, Laure, additional, Burtey, Stephane, additional, Busch, Martin, additional, Cakiroglu, Figen, additional, Campbell, Victoria, additional, Canetta, Pietro, additional, Capaccio, Flavia, additional, Carbonell, Juan, additional, Cardoso, Filipa, additional, Carro, Clara Garcia, additional, Carroll, Robert, additional, Carron, Pierre-Louis, additional, Carullo, Nazareno, additional, Cassia, Matthias, additional, Caster, Dawn, additional, Castillo, Belen Vizcaino, additional, Catucci, Davide, additional, Cavalli, Andrea, additional, Chakera, Aron, additional, Chan, Doris, additional, Chan, Gary Chi Wang, additional, Chan, Anthony Ting Pong, additional, Chan, Lai Wan, additional, Chang, Jae Hyun, additional, Chang, Ming-Shan, additional, Chapman, Fiona, additional, Charytan, Chaim, additional, Chaudhry, Asghar, additional, Cheetham, Melissa, additional, Chen, Cheng-Hsu, additional, Chen, Hsin-Yu, additional, Chen, Chien-Liang, additional, Chen, Hung-Yuan, additional, Chen, Hung-Chun, additional, Chenine, Leila, additional, Cheung, Siu Fai, additional, Cheung, Chee Kay, additional, Chiche-Jourde, Noemie, additional, Chiu, Hsien-Fu, additional, Chiu, Yen-Ling, additional, Chiu, Yi-Wen, additional, Chiu, Ian, additional, Choi, Hoon Young, additional, Chou, Kang-Ju, additional, Chowdhury, Paramit, additional, Chowdhury, Pradip, additional, Chrysochou, Constantina, additional, Chukwu, Chukwuma, additional, Chun, Ka Yeong, additional, Chung, Wookyung, additional, Cieniawski, Dominik, additional, Claisse, Guillaume, additional, Clayton, Philip, additional, Cleary, Catalina Martín, additional, Clement, Nisha, additional, Coates, Toby, additional, Cogno, Chiara, additional, Colla, Loredana, additional, Collins, Michael, additional, Colucci, Marco, additional, Combe, Christian, additional, Comi, Nicolino, additional, Comunale, Roderick, additional, Contreras, Gabriel, additional, Cooper, Bruce, additional, Coppock, Gaia, additional, Costa, Ana Cortesão, additional, Costanzi, Stefano, additional, Cozzolino, Mario, additional, Crail, Susan, additional, Cunha, Liliana, additional, Curry, Elizabeth, additional, Dai, Tiane, additional, Daina, Erica, additional, Daneshvari, Sam, additional, Dasgupta, Indranil, additional, DaSilva, Louise, additional, Davidson, Robert, additional, De Bhailis, Aine Maire, additional, de Précigout, Valérie, additional, Decupere, Marc, additional, Delmas, Yahsou, additional, Deodato, Francesca, additional, Dhaun, Neeraj, additional, Dhaygude, Ajay, additional, Dhelaria, Ranjit, additional, Di Maio, Federica, additional, Diezhandino, Maria Angeles Goicoechea, additional, Dika, Zivka, additional, Dinic, Miriana, additional, Dittmer, Ian, additional, Dobre, Mirela, additional, Doctor, Gabriel, additional, Donati, Gabriele, additional, Doubel, Peter, additional, Douthit, Nicole, additional, Draganova, Diliana, additional, Drexler, Yelena, additional, Drinkovic, Martin, additional, Drinovska, Klara, additional, Dudreuilh, Caroline, additional, Dumond, Clement, additional, Durlen, Ivan, additional, Dussol, Bertrand, additional, Encarnacion, Montserrat Diaz, additional, Endre, Zoltan, additional, Enrique, Jorge, additional, Eqbal, Yusuf, additional, Erlich, Jonathan, additional, Esposito, Vittoria, additional, Esposito, Ciro, additional, Fakih, Faisal, additional, Fang, Hua-Chang, additional, Farinha, Ana, additional, Fearday, Aaron, additional, Felgueiras, Joana de Sousa Soares, additional, Felicjanczuk, Elzbieta, additional, Fernandes, João Carlos, additional, Fernandes, Sara, additional, Fernandes, Adriana, additional, Fernandez, Jose Luño, additional, Fernandez, Victor, additional, Fernando, Mangalee, additional, Figueiredo, Ana Carolina, additional, Firre, Eric, additional, Flossmann, Oliver, additional, Floyd, Lauren, additional, Fonseca, Nuno, additional, Fonseca, Jose Nuno de Almeida Agapito, additional, Foote, Celine, additional, Forbes, Suzanne, additional, Forcen, Angel, additional, Fornoni, Alessia, additional, Fouassier, David, additional, Fraser, Ian, additional, Fung, Ka Shun Samuel, additional, Furlano, Monica, additional, Furtado, Teresa, additional, Gadh, Rajdeep, additional, Gaisset, Roxane, additional, Gallagher, Martin, additional, Gameiro, Joana, additional, Gangadharan, Muralikrishna, additional, Garcia, Fabiola Alonso, additional, Garcia, Olga Gracia, additional, Garg, Gunjan, additional, Garrouste, Cyril, additional, Gautam, Archana, additional, Geara, Abdallah, additional, Geddes, Colin, additional, Gellineo, Lana, additional, Germain, Michael, additional, Ghalli, Farid, additional, Giaroni, Francesco, additional, Giles, Harold, additional, Gillies, Alastair, additional, Gimeno, Ana Vilar, additional, Girardet, Annette, additional, Glaze, Jeffrey, additional, Goh, Tze, additional, Gois, Mario, additional, Goldsmith, Christopher, additional, Goma, Elena, additional, Gomes, Ana Marta, additional, Goncalves, Luis Pedro Falcao, additional, Goncalves, Sara, additional, Gontarek-Kacprzak, Julita, additional, Gonzalez, Carlos, additional, Gopu, Arun, additional, Gowda, Nayan, additional, Gray, Nicholas, additional, Greco, Barbara, additional, Green, Heather, additional, Greze, Clarisse, additional, Griffin, Sian, additional, Guldris, Secundino Cigarran, additional, Guzman, Ursula Verdalles, additional, Ha, Jeffrey Tsun Kit, additional, Hall, Amanda, additional, Hamilton, Patrick, additional, Han, Seung Hyeok, additional, Haws, Robert, additional, Hayat, Ashik, additional, Heath, Lauren, additional, Heinrichs, Sven, additional, Henderson, Andrew, additional, Henderson, Amy, additional, Hendren, Elizabeth, additional, Heng, Anne-Elisabeth, additional, Heres, Salia Virxinia Pol, additional, Herfurth, Johann Konstantin, additional, Herrero, Evangelina Merida, additional, Ho, Tzung-Yo, additional, Hogan, Jonathan, additional, Hohenstein, Bernd, additional, Hollett, Peter, additional, Horvatic, Ivica, additional, Hsu, Bang-Gee, additional, Hsu, Chia-Tien, additional, Hsu, Chih-Yang, additional, Hsu, Shih-Ping, additional, Huang, Chien-Wei, additional, Hudson, Amy, additional, Hung, Chi-Chih, additional, Hwang, Shang-Jyh, additional, Hwang, Daw-Yang, additional, Hyun, Young Youl, additional, Ilmoja, Madis, additional, Irish, Georgina, additional, Jacob, Radu, additional, Jahan, Sadia, additional, Jain, Arunima, additional, Jamar, Sofie, additional, Jander, Anna, additional, Jang, Hye Ryoun, additional, Janko, Catherine, additional, Jardine, Meg, additional, Jaskowski, Piotr, additional, Jeantet, Guillaume, additional, Jelakovic, Bojan, additional, Jeon, Junseok, additional, Jeong, Jong Cheol, additional, Jesudason, Shilpanjali, additional, Jittirat, Arksarapuk, additional, Jo, Sang-Kyung, additional, Jones, Rachel, additional, Joo, Narae, additional, Jorge, Sofia, additional, Julian, Bruce, additional, Jung, JiYong, additional, Jyothinagaram, Praveena, additional, Kadakia, Jigar, additional, Kamal, Fahameedah, additional, Kanigicherla, Durga, additional, Karanovic, Sandra, additional, Karras, Alexandre, additional, Kasimatis, Theodoros, additional, Kassem, Mohamad, additional, Kattamanchi, Siddhartha, additional, Keller, Christopher, additional, Kentric, Dubravka Trajbar, additional, Kettner, Christiane, additional, Khalil, Kassem, additional, Kim, Dana, additional, Kim, Se Joong, additional, Kim, Yeong Hoon, additional, Kim, Yunmi, additional, Kim, Hyung Wook, additional, Kim, Sunggyun, additional, Kim, Jwa-Kyung, additional, Kim, Aejin, additional, Kim, Myung-Gyu, additional, Kimber, Cassandra, additional, Klamm, Kathryn, additional, Koch, Annegret, additional, Koester, Eric, additional, Kolvald, Kulli, additional, Kon, Sui, additional, Kotwal, Sradha, additional, Krajewska, Magdalena, additional, Kratka, Karolina, additional, Krishnan, Anoushka, additional, Krishnasamy, Rathika, additional, Krueger, Thilo, additional, Kruljac, Ivan, additional, Kulka, Simone, additional, Kunzendorf, Ulrich, additional, Kuo, Mei-Chuan, additional, Kuo, Hung-Tien, additional, Kuo, Sheng, additional, Kwan, Lorraine Pui Yuen, additional, Kwella, Norbert, additional, Kwella, Bogna, additional, Kyaw, Kay, additional, Labat, Aurore, additional, Lagatta, Mark, additional, Lam, Chi Kwan Darwin, additional, Lambie, Mark, additional, Lanaret, Camille, additional, Latif, Farah, additional, Laute, Margo, additional, Law, Wai Ping, additional, Lawman, Sarah, additional, Lazo, Mercedes Salgueira, additional, Lee, Hajeong, additional, Lee, Moon Hyoung, additional, Lee, Kyu-Beck, additional, Lee, Hyung-seok, additional, Lee, JungEun, additional, Lee, Hyun Hee, additional, Lee, Po-Tsang, additional, Leis, Liisi, additional, Lemahieu, Wim, additional, Leung, Janson, additional, Li, Yan, additional, Lie, Davina Ngoi Wah, additional, Lifland, Howard, additional, Lilienthal, Kadri, additional, Lim, Wai, additional, Limardo, Monica, additional, Livrozet, Marine, additional, Longhi, Selena, additional, Lopes, Daniela, additional, Lopes, Jose Antonio, additional, Lorde, Nathan, additional, Luxton, Grant, additional, Ma, Mingyao, additional, Madhrira, Machaiah, additional, Madonia, Phillip, additional, Mahadevan, Kumaradevan, additional, Mahdi, Amar, additional, Mahdi, Eamon, additional, Maillard, Nicolas, additional, Maixnerova, Dita, additional, Majstorovic Barac, Karolina, additional, Malecki, Robert, additional, Malfait, Thomas, additional, Malvica, Silvia, additional, Mandayam, Sreedhar, additional, Manley, Paul, additional, Mansfield, Nick, additional, Marcantoni, Carmelita, additional, Mariat, Christophe, additional, Marin, Tamara Malek, additional, Marin, Lida Maria Rodas, additional, Mark, Patrick, additional, Marques, Joana, additional, Martinez, Eduardo Gutierrez, additional, Martinez, Stacy, additional, Masset, Catherine, additional, Masson, Ingrid, additional, Mather, Amanda, additional, Maung Myint, Thida Maung, additional, Mayet, Valentin, additional, McCafferty, Kieran, additional, McCarthy, Ellen, additional, McDonald, Stephen, additional, McGreal, Kerri, additional, McMahon, Kellyn, additional, McNally, Andrew, additional, McQuarrie, Emily, additional, Medina, Allyson, additional, Meeus, Gert, additional, Mehta, Kshama, additional, Mendoza, Elder, additional, Menezes, Maria, additional, Meng, Jerry, additional, Messa, Piergiorgio, additional, Messias, Ana, additional, Miarka, Przemyslaw, additional, Miglinas, Marius, additional, Mikacic, Ivana, additional, Mikhail, Ashraf, additional, Milicevic, Martina, additional, Minasian, Raffi, additional, Moeller, Marcus, additional, Mohey, Hesham, additional, Mojarrab, Javad, additional, Mok, Maggie Ming Yee, additional, Moncasi, Eduardo Parra, additional, Moonen, Martial, additional, Morales, Wenceslao Adrian Aguilera, additional, Moreno, Eduardo Verde, additional, Moreno, Antolina, additional, Morris, Adam, additional, Moutzouris, Dimitrios, additional, Moya, Mercedes Gonzalez, additional, Mucha, Simon, additional, Musolino, Michela, additional, Napodano, Pietro, additional, Natario, Ana, additional, Negrea, Lavinia, additional, Nelson, Bradley, additional, Neuen, Brendon, additional, Newsome, Britt, additional, Ng, Kit Chung Jack, additional, Nguyen, Thu, additional, Nguyen, Viet, additional, Nicolo, Clementine, additional, Nitschke, Martin, additional, Noble, Euan, additional, Nolasco, Fernando, additional, O'Lone, Emma, additional, Ochoa, Adriana Sierra, additional, Oh, Kook-Hwan, additional, Oh, SeWon, additional, Okoh, Pedro, additional, Ombelet, Sara, additional, O'Shaughnessy, Michelle, additional, Ou, Shih-Hsiang, additional, Packham, David, additional, Padiyar, Aparna, additional, Pai, Mei-Fen, additional, Pamplona, Irene Agraz, additional, Pan, Szu-Yu, additional, Pandya, Bhavna, additional, Papadia, Federica, additional, Pardinhas, Clara, additional, Parikh, Nishita, additional, Parikh, Samir, additional, Park, Hyeong Cheon, additional, Park, Jung Tak, additional, Parreira, Lucia, additional, Passerini, Patrizia, additional, Patak, Ramachandra, additional, Patecki, Margret, additional, Patel, Rajan, additional, Patel, Jusmin, additional, Patel Suthar, Meera, additional, Patella, Gemma, additional, Patrikyan, Artashes, additional, Pavlovic, Drasko, additional, Paxton, William, additional, Peh, Chen, additional, Peleg, Yonatan, additional, Pelicano, Josep Miquel Blasco, additional, Peng, Yu-Sen, additional, Pereira de Vicente, Manuel, additional, Perez, Jonay Pantoja, additional, Perez, Erika, additional, Perez de Jose, Ana, additional, Pérez Gómez, María Vanessa, additional, Perez Lluna, Leticia, additional, Peri, Usha, additional, Perico, Norberto, additional, Philipponnet, Carole, additional, Phua, Elaine, additional, Piel, Julia, additional, Pillai, Unnikrishnan, additional, Pilmore, Helen, additional, Plavljanic, Djuro, additional, Plaza, Mercedes Velo, additional, Pollock, Carol, additional, Ponnusamy, Arvind, additional, Ponti, Serena, additional, Powell, Thomas, additional, Pradhan, Nishigandha, additional, Prado, Raul Fernandez, additional, Prkacin, Ingrid, additional, Pruthi, Rishi, additional, Pugh, Dan, additional, Quinn, Sarah, additional, Quintana, Luis F, additional, Raakesh, Lathika, additional, Rabindranath, Kannaiyan, additional, Radermacher, Luc, additional, Ragy, Omar Sherin Ibrahim, additional, Raichoudhury, Ritesh, additional, Raimundo, Mario, additional, Randone, Paolo, additional, Razavian, Mona, additional, Reichel, Helmut, additional, Reis, Marina, additional, Remuzzi, Giuseppe, additional, Reynolds, Annie, additional, Ricchiuto, Anna, additional, Rico, Ivon Maritza Bobadilla, additional, Rigothier, Claire, additional, Ritchie, Angus, additional, Rivero, Maria Antonieta Azancot, additional, Rizk, Dana, additional, Ro, Han, additional, Rodriguez, Alfred, additional, Rodriguez Garcia, Eva, additional, Roger, Simon, additional, Rony, Mohammad, additional, Rosenberg, Mai, additional, Roueff, Stephane, additional, Rovin, Brad, additional, Roxburgh, Sarah, additional, Ruiz, Mario, additional, Rusinol, Helena Marco, additional, Rychlik, Ivan, additional, Sá, Helena, additional, Salehi, Tania, additional, Sánchez de la Nieta, Maria Dolores, additional, Sanden, Silja, additional, Santockiene, Lina, additional, Santos, Patricia Valerio, additional, Santos, Iara Da Silva, additional, Sargsyan, Mari, additional, Sarnow, Franziska, additional, Sat, Sebahat, additional, Satora, Ewa, additional, Savuk, Ana, additional, Sayer, Matthew, additional, Schlieper, Georg, additional, Schlosser, Mandy, additional, Schmidt-Guertler, Hans, additional, Schockaert, Olivier, additional, Schulte, Kevin, additional, Schulz, Lisa, additional, Selvaskandan, Haresh, additional, Semple, David, additional, Sen, Shaundeep, additional, Seppet, Elviira, additional, Serrano, Antonio Galan, additional, Serre, Jean-Emmanuel, additional, Sevillano, Angel, additional, Shah, Sapna, additional, Shen, Yvonne, additional, Sheridan, Brittany, additional, Shu, Kai-Hsiang, additional, Sightler, Ford, additional, Silva, Sónia, additional, Silva, Arnold, additional, Sinha, Smeeta, additional, Siriwardana, Amanda, additional, Sitas, Zvonimir, additional, Sivo, Carmen, additional, Sizeland, Peter, additional, Sly, Cathylee, additional, Smith, Priscilla, additional, Snow, Brian, additional, Soares, Elsa Sofia Quadrado, additional, Solazzo, Andrea, additional, Solis, Elena Gutierrez, additional, Solomon, Laurence, additional, Song, Young Rim, additional, Sousa, Helena, additional, Spinowitz, Bruce, additional, Stallworthy, Elizabeth, additional, Stamellou, Eleni, additional, Stanczyk, Malgorzata, additional, Stangenberg, Stefanie, additional, Stankovic, Marija, additional, Stankuviene, Asta, additional, Stea, Emma Diletta, additional, Stompor, Tomasz, additional, Storrar, Joshua, additional, Sullivan, James, additional, Sulowicz, Wladyslaw, additional, Suyumova, Irina, additional, Szeto, Cheuk Chun, additional, Tamarit, Esther, additional, Tan, Eddie, additional, Tan, May, additional, Tang, Sydney Chi Wai, additional, Tang, Hon, additional, Teixeira, Catarina, additional, Telling, Kadri, additional, Terrades, Natalia Ramos, additional, Tez, Didem, additional, Thervet, Eric, additional, Thibaudin, Damien, additional, Thomas, Mark, additional, Thyagarajan, Nikhil, additional, Tkaczyk, Marcin, additional, Torreggiani, Massimo, additional, Trillini, Matias, additional, Tsai, Shang-Feng, additional, Tsai, Wan-Chuan, additional, Tsai, Jer-Chia, additional, Tseng, Po-Yu, additional, Tumlin, James, additional, Tung, Kuei-Ting, additional, Turnbull, Angus, additional, Udani, Suneel, additional, Uhlinova, Jana, additional, Unt, Kristin, additional, Urciuolo, Federica, additional, Vanacker, An, additional, Vandewiele, Bert, additional, Vaz, Alvaro, additional, Veermae, Kristi, additional, Viaene, Liesbeth, additional, Vickiene, Alvita, additional, Vigano, Sara, additional, Vila, Maria Antonia Munar, additional, Vilayur, Eswari, additional, Villanueva, Caridad Martinez, additional, Villarroya, Cristina Medrano, additional, Villen, Alejandro Soria, additional, Viramontes, Veronica, additional, Vita, Caterina, additional, Vujcic, Dunja, additional, Wahba, Mona, additional, Wan, Susan, additional, Wang, Chih-Hsien, additional, Warling, Xavier, additional, Waters, Gerald, additional, Waugh, Jane, additional, Weiland, Lea, additional, Weiner, Stefan, additional, Weinreich, Thomas, additional, Werth, Stephan Christian, additional, Wickens, Olivia, additional, Wijeratne, Vidu, additional, Wilder, Karen, additional, Willcocks, Lisa, additional, Williams, Allister, additional, Winiarska, Agata, additional, Wirtz, Nikolaus, additional, Wolf, Lothar, additional, Wolf, Gunter, additional, Wong, Yick Hei, additional, Wong, Sze Ho Sunny, additional, Workeneh, Biruh, additional, Wu, Ming-Ju, additional, Wu, Hon-Yen, additional, Wyndham, Roger, additional, Yang, Jihyun, additional, Yang, Ju-Yeh, additional, Yeap, Chii, additional, Yim, Ka Fai, additional, Yong, Kenneth, additional, Yoo, Tae-Hyun, additional, Yoon, Songuk, additional, Yu, Tung-Min, additional, Yue, Tak Tai Andrew, additional, Zakari, Michel, additional, Zakauskiene, Urte, additional, Zaoui, Philippe, additional, Zbrzezniak, Justyna, additional, Zielinska, Dorota, additional, and Zizzi, Carlotta Federica, additional

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2023
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10. Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial

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Heerspink, Hiddo J L, primary, Radhakrishnan, Jai, additional, Alpers, Charles E, additional, Barratt, Jonathan, additional, Bieler, Stewart, additional, Diva, Ulysses, additional, Inrig, Jula, additional, Komers, Radko, additional, Mercer, Alex, additional, Noronha, Irene L, additional, Rheault, Michelle N, additional, Rote, William, additional, Rovin, Brad, additional, Trachtman, Howard, additional, Trimarchi, Hernán, additional, Wong, Muh Geot, additional, Perkovic, Vlado, additional, Alarmartine, Eric, additional, Chae, Dong Wan, additional, Del Vecchio, Lucia, additional, Floege, Jurgen, additional, Hwang, Shang-Jyh, additional, Jelakovic, Bojan, additional, Maes, Bart, additional, Malecki, Robert, additional, Miglinas, Marius, additional, Nolasco, Fernando Eduardo Barbosa, additional, Praga, Manual, additional, Rabindranath, Kannaiyan, additional, Rosenberg, Mai, additional, Tang, Sydney Chi Wai, additional, Tesar, Vladmir, additional, Bose, Bhadran, additional, Gangadharan, Muralikrishna, additional, McDonald, Stephen, additional, Peh, Chen, additional, Jahan, Sadia, additional, Yeap, Chii, additional, Clayton, Philip, additional, Irish, Georgina, additional, Thyagarajan, Nikhil, additional, Hollett, Peter, additional, Krishnasamy, Rathika, additional, Carroll, Robert, additional, Jesudason, Shilpanjali, additional, Crail, Susan, additional, Coates, Toby, additional, Waugh, Jane, additional, Noble, Euan, additional, Mahadevan, Kumaradevan, additional, Campbell, Victoria, additional, Salehi, Tania, additional, Lim, Wai, additional, Boudville, Neil, additional, Chakera, Aron, additional, Chan, Doris, additional, Krishnan, Anoushka, additional, Eqbal, Yusuf, additional, Gillies, Alastair, additional, Vilayur, Eswari, additional, Maung Myint, Thida Maung, additional, Gray, Nicholas, additional, Cheetham, Melissa, additional, Pollock, Carol, additional, Cooper, Bruce, additional, Mather, Amanda, additional, Roxburgh, Sarah, additional, Shen, Yvonne, additional, Stangenberg, Stefanie, additional, Siriwardana, Amanda, additional, O'Lone, Emma, additional, Wan, Susan, additional, Neuen, Brendon, additional, Tsun Kit Ha, Jeffrey, additional, Kim, Dana, additional, Heath, Lauren, additional, Jain, Arunima, additional, Phua, Elaine, additional, Li, Yan, additional, Gallagher, Martin, additional, Jardine, Meg, additional, Ritchie, Angus, additional, Razavian, Mona, additional, Foote, Celine, additional, Wyndham, Roger, additional, Sen, Shaundeep, additional, Endre, Zoltan, additional, Erlich, Jonathan, additional, Fernando, Mangalee, additional, Yong, Kenneth, additional, Luxton, Grant, additional, Kotwal, Sradha, additional, Roger, Simon, additional, Wijeratne, Vidu, additional, Packham, David, additional, Fraser, Ian, additional, Vandewiele, Bert, additional, Laute, Margo, additional, Lemahieu, Wim, additional, Jamar, Sofie, additional, Ombelet, Sara, additional, Meeus, Gert, additional, Decupere, Marc, additional, Schockaert, Olivier, additional, Doubel, Peter, additional, Viaene, Liesbeth, additional, Radermacher, Luc, additional, Masset, Catherine, additional, Moonen, Martial, additional, Firre, Eric, additional, Milicevic, Martina, additional, Warling, Xavier, additional, Vanacker, An, additional, Malfait, Thomas, additional, Durlen, Ivan, additional, Horvatic, Ivica, additional, Savuk, Ana, additional, Gellineo, Lana, additional, Karanovic, Sandra, additional, Dika, Zivka, additional, Plavljanic, Djuro, additional, Mikacic, Ivana, additional, Trajbar Kentric, Dubravka, additional, Barisic, Dunja, additional, Stankovic, Marija, additional, Majstorovic Barac, Karolina, additional, Kruljac, Ivan, additional, Pavlovic, Drasko, additional, Drinkovic, Martin, additional, Prkacin, Ingrid, additional, Barbic, Jerko, additional, Sitas, Zvonimir, additional, Vujcic, Dunja, additional, Rychlik, Ivan, additional, Benesova, Anna, additional, Drinovska, Klara, additional, Kratka, Karolina, additional, Maixnerova, Dita, additional, Ilmoja, Madis, additional, Unt, Kristin, additional, Lilienthal, Kadri, additional, Auerbach, Asta, additional, Leis, Liisi, additional, Piel, Julia, additional, Adoberg, Annika, additional, Kolvald, Kulli, additional, Veermae, Kristi, additional, Telling, Kadri, additional, Seppet, Elviira, additional, Uhlinova, Jana, additional, Zaoui, Philippe, additional, Carron, Pierre-Louis, additional, Masson, Ingrid, additional, Dinic, Miriana, additional, Thibaudin, Damien, additional, Broyet, Christian, additional, Maillard, Nicolas, additional, Mohey, Hesham, additional, Mariat, Christophe, additional, Claisse, Guillaume, additional, Alamartine, Eric, additional, Dussol, Bertrand, additional, Burtey, Stephane, additional, Chiche-Jourde, Noemie, additional, Serre, Jean-Emmanuel, additional, Jeantet, Guillaume, additional, Chenine, Leila, additional, Blanchard, Anne, additional, Roueff, Stephane, additional, Thervet, Eric, additional, Fouassier, David, additional, Buffet, Alexandre, additional, Livrozet, Marine, additional, Gaisset, Roxane, additional, Karras, Alexandre, additional, Heng, Anne-Elisabeth, additional, Garrouste, Cyril, additional, Philipponnet, Carole, additional, Nicolo, Clementine, additional, Atenza, Alba, additional, Lanaret, Camille, additional, Greze, Clarisse, additional, Mayet, Valentin, additional, Dumond, Clement, additional, Delmas, Yahsou, additional, Combe, Christian, additional, Rigothier, Claire, additional, Burguet, Laure, additional, Labat, Aurore, additional, Mucha, Simon, additional, de Précigout, Valérie, additional, Weinreich, Thomas, additional, Reichel, Helmut, additional, Draganova, Diliana, additional, Wolf, Lothar, additional, Hohenstein, Bernd, additional, Heinrichs, Sven, additional, Kulka, Simone, additional, Sat, Sebahat, additional, Weiland, Lea, additional, Krueger, Thilo, additional, Wolf, Gunter, additional, Kettner, Christiane, additional, Schlosser, Mandy, additional, Herfurth, Johann Konstantin, additional, Koch, Annegret, additional, Busch, Martin, additional, Werth, Stephan Christian, additional, Nitschke, Martin, additional, Cakiroglu, Figen, additional, Sarnow, Franziska, additional, Schulz, Lisa, additional, Weiner, Stefan, additional, Wirtz, Nikolaus, additional, Koester, Eric, additional, Moeller, Marcus, additional, Stamellou, Eleni, additional, Sanden, Silja, additional, Schmidt-Guertler, Hans, additional, Bernhardt, Wanja, additional, Patecki, Margret, additional, Schlieper, Georg, additional, Schulte, Kevin, additional, Girardet, Annette, additional, Kunzendorf, Ulrich, additional, Kwan, Lorraine Pui Yuen, additional, Mok, Maggie Ming Yee, additional, Chan, Gary Chi Wang, additional, Ma, Mingyao, additional, Lie, Davina Ngoi Wah, additional, Chan, Anthony Ting Pong, additional, Szeto, Cheuk Chun, additional, Ng, Kit Chung Jack, additional, Cheung, Siu Fai, additional, Yue, Tak Tai Andrew, additional, Fung, Ka Shun Samuel, additional, Tang, Hon, additional, Yim, Ka Fai, additional, Law, Wai Ping, additional, Wong, Yick Hei, additional, Lam, Chi Kwan Darwin, additional, Wong, Sze Ho Sunny, additional, Marcantoni, Carmelita, additional, Aliotta, Roberta, additional, Deodato, Francesca, additional, Patella, Gemma, additional, Comi, Nicolino, additional, Vita, Caterina, additional, Carullo, Nazareno, additional, Bolignano, Davide, additional, Musolino, Michela, additional, Trillini, Matias, additional, Perico, Norberto, additional, Remuzzi, Giuseppe, additional, Daina, Erica, additional, Biancone, Luigi, additional, Colla, Loredana, additional, Burdese, Manuel, additional, Cogno, Chiara, additional, Boaglio, Elena, additional, Abbasciano, Isabella, additional, Zizzi, Carlotta Federica, additional, Randone, Paolo, additional, Napodano, Pietro, additional, Ricchiuto, Anna, additional, Cassia, Matthias, additional, Accarino, Simone, additional, Cozzolino, Mario, additional, Baccaro, Rocco, additional, Costanzi, Stefano, additional, Di Maio, Federica, additional, Arena, Maria, additional, Urciuolo, Federica, additional, Vigano, Sara, additional, Cavalli, Andrea, additional, Limardo, Monica, additional, Bordoli, Monica, additional, Ponti, Serena, additional, Longhi, Selena, additional, Solazzo, Andrea, additional, Giaroni, Francesco, additional, Donati, Gabriele, additional, Torreggiani, Massimo, additional, Catucci, Davide, additional, Colucci, Marco, additional, Esposito, Vittoria, additional, Esposito, Ciro, additional, Gesualdo, Loreto, additional, Capaccio, Flavia, additional, Diletta Stea, Emma, additional, Sivo, Carmen, additional, Annese, Francesca, additional, Papadia, Federica, additional, Messa, Piergiorgio, additional, Belingheri, Mirco, additional, Passerini, Patrizia, additional, Malvica, Silvia, additional, Vickiene, Alvita, additional, Zakauskiene, Urte, additional, Asakiene, Egle, additional, Bumblyte', Inga Arune, additional, Stankuviene, Asta, additional, Santockiene, Lina, additional, Hayat, Ashik, additional, Williams, Allister, additional, Sizeland, Peter, additional, Tan, Eddie, additional, Waters, Gerald, additional, Chan, Lai Wan, additional, Henderson, Andrew, additional, Turnbull, Angus, additional, McNally, Andrew, additional, Reynolds, Annie, additional, Pilmore, Helen, additional, Dittmer, Ian, additional, Manley, Paul, additional, Stallworthy, Elizabeth, additional, Goh, Tze, additional, Semple, David, additional, Collins, Michael, additional, Curry, Elizabeth, additional, Ahmed, Jafar, additional, Nguyen, Thu, additional, Winiarska, Agata, additional, Zbrzezniak, Justyna, additional, Stompor, Tomasz, additional, Krajewska, Magdalena, additional, Augustyniak-Bartosik, Hanna, additional, Zielinska, Dorota, additional, Jander, Anna, additional, Stanczyk, Malgorzata, additional, Tkaczyk, Marcin, additional, Miarka, Przemyslaw, additional, Aksamit, Dariusz, additional, Jaskowski, Piotr, additional, Sulowicz, Wladyslaw, additional, Cieniawski, Dominik, additional, Gontarek-Kacprzak, Julita, additional, Felicjanczuk, Elzbieta, additional, Kwella, Norbert, additional, Kwella, Bogna, additional, Satora, Ewa, additional, Fernandes, João Carlos, additional, Gomes, Ana Marta, additional, Reis, Marina, additional, Lopes, Daniela, additional, Almeida, Catarina, additional, Sá, Helena, additional, Figueiredo, Ana Carolina, additional, Pardinhas, Clara, additional, Almeida, Edgar, additional, Raimundo, Mario, additional, Cortesão Costa, Ana, additional, Falcao Goncalves, Luis Pedro, additional, Fernandes, Sara, additional, Silva, Sónia, additional, Teixeira, Catarina, additional, Fernandes, Adriana, additional, Nolasco, Fernando, additional, Alves, Patricia, additional, Gois, Mario, additional, Fonseca, Nuno, additional, Messias, Ana, additional, Menezes, Maria, additional, Cardoso, Filipa, additional, Sousa, Helena, additional, Marques, Joana, additional, Barata, Rui, additional, Lopes, Jose Antonio, additional, Jorge, Sofia, additional, Gameiro, Joana, additional, de Almeida Agapito Fonseca, Jose Nuno, additional, Goncalves, Sara, additional, Farinha, Ana, additional, Valerio Santos, Patricia, additional, Natario, Ana, additional, de Jesus Barreto, Jose Carlos, additional, Abrantes, Catarina, additional, Quadrado Soares, Elsa Sofia, additional, Soares Felgueiras, Joana de Sousa, additional, Cunha, Liliana, additional, Parreira, Lucia, additional, Furtado, Teresa, additional, Vaz, Alvaro, additional, Oh, Kook-Hwan, additional, Lee, Hajeong, additional, Joong Kim, Se, additional, Jeong, Jong Cheol, additional, Hoon Kim, Yeong, additional, Kim, Yunmi, additional, Park, Hyeong Cheon, additional, Choi, Hoon Young, additional, Wook Kim, Hyung, additional, Lee, Moon Hyoung, additional, Yoon, Songuk, additional, Lee, Kyu-Beck, additional, Hyun, YoungYoul, additional, Yoo, Tae-Hyun, additional, Han, Seung Hyeok, additional, Park, Jung Tak, additional, Kim, Sunggyun, additional, Song, Young Rim, additional, Kim, Jwa-Kyung, additional, Lee, Hyung-seok, additional, Joo, Narae, additional, Lee, JungEun, additional, Ryoun Jang, Hye, additional, Jeon, Junseok, additional, Chung, Wookyung, additional, Lee, HyunHee, additional, Chang, Jae Hyun, additional, Chun, Ka Yeong, additional, Jung, Ji Yong, additional, Ro, Han, additional, Kim, Aejin, additional, Jo, Sang-Kyung, additional, Yang, Jihyun, additional, Kim, Myung-Gyu, additional, Oh, SeWon, additional, Martinez Villanueva, Caridad, additional, Gimeno, Ana Vilar, additional, Andres Useche Bonilla, Gustavo, additional, Tamarit, Esther, additional, Galan Serrano, Antonio, additional, Verde Moreno, Eduardo, additional, Fernandez, Jose Luño, additional, Goicoechea Diezhandino, Maria Angeles, additional, Verdalles Guzman, Ursula, additional, de Jose, Ana Perez, additional, Ortiz Arduan, Alberto, additional, Pérez Gómez, María Vanessa, additional, Martín Cleary, Catalina, additional, Prado, Raul Fernandez, additional, Goma, Elena, additional, Ballarin, Jose, additional, Encarnacion, Montserrat Diaz, additional, Da Silva Santos, Iara, additional, Marco Rusinol, Helena, additional, Furlano, Monica, additional, Arias, Carlos, additional, Barrios, Clara, additional, Garcia, Eva Rodriguez, additional, Sierra Ochoa, Adriana, additional, Vizcaino Castillo, Belen, additional, Pantoja Perez, Jonay, additional, Gonzalez Moya, Mercedes, additional, Sargsyan, Mari, additional, Calatayud Aristoy, Emma, additional, Bernabeu, Ana Avila, additional, Perez Lluna, Leticia, additional, Malek Marin, Tamara, additional, Antonia Munar Vila, Maria, additional, Bobadilla Rico, Ivon Maritza, additional, Allende Burgos, Natalia, additional, Gutierrez Martinez, Eduardo, additional, Gutierrez Solis, Elena, additional, Sevillano, Angel, additional, Merida Herrero, Evangelina, additional, Miquel Blasco Pelicano, Josep, additional, Rodas Marin, Lida Maria, additional, Quintana, Luis F, additional, Antonieta Azancot Rivero, Maria, additional, Ramos Terrades, Natalia, additional, Garcia Carro, Clara, additional, Agraz Pamplona, Irene, additional, Salgueira Lazo, Mercedes, additional, de la Prada Alvarez, Francisco, additional, Alonso Garcia, Fabiola, additional, Adrian Aguilera Morales, Wenceslao, additional, Virxinia Pol Heres, Salia, additional, Forcen, Angel, additional, Parra Moncasi, Eduardo, additional, Medrano Villarroya, Cristina, additional, Soria Villen, Alejandro, additional, Gracia Garcia, Olga, additional, Velo Plaza, Mercedes, additional, Sánchez de la Nieta, Maria Dolores, additional, Calvo Arevalo, Marta, additional, Moreno, Antolina, additional, Cigarran Guldris, Secundino, additional, de Vicente, Manuel Pereira, additional, Munar Vila, Maria Antonia, additional, Hsu, Bang-Gee, additional, Wang, Chih-Hsien, additional, Chen, Cheng-Hsu, additional, Yu, Tung-Min, additional, Wu, Ming-Ju, additional, Tsai, Shang-Feng, additional, Hsu, Chia-Tien, additional, Chiu, Hsien-Fu, additional, Chou, Kang-Ju, additional, Fang, Hua-Chang, additional, Lee, Po-Tsang, additional, Chen, Hsin-Yu, additional, Chen, Chien-Liang, additional, Huang, Chien-Wei, additional, Ou, Shih-Hsiang, additional, Ho, Tzung-Yo, additional, Hsu, Chih-Yang, additional, Chang, Ming-Shan, additional, Chiu, Yen-Ling, additional, Peng, Yu-Sen, additional, Shu, Kai-Hsiang, additional, Pan, Szu-Yu, additional, Hsu, Shih-Ping, additional, Yang, Ju-Yeh, additional, Pai, Mei-Fen, additional, Tseng, Po-Yu, additional, Wu, Hon-Yen, additional, Tsai, Wan-Chuan, additional, Tung, Kuei-Ting, additional, Chen, Hung-Yuan, additional, Chen, Hung-Chun, additional, Kuo, Mei-Chuan, additional, Hwang, Daw-Yang, additional, Chiu, Yi-Wen, additional, Hung, Chi-Chih, additional, Kuo, Hung-Tien, additional, Tsai, Jer-Chia, additional, McCafferty, Kieran, additional, Forbes, Suzanne, additional, Dasgupta, Indranil, additional, Thomas, Mark, additional, Mahdi, Amar, additional, Ajayi, Bamidele, additional, Chowdhury, Paramit, additional, Kasimatis, Theodoros, additional, Moutzouris, Dimitrios, additional, Dudreuilh, Caroline, additional, Pruthi, Rishi, additional, Mansfield, Nick, additional, Doctor, Gabriel, additional, Shah, Sapna, additional, Kon, Sui, additional, Smith, Priscilla, additional, Hamilton, Patrick, additional, Kanigicherla, Durga, additional, Ibrahim Ragy, Omar Sherin, additional, Alchi, Bassam, additional, Flossmann, Oliver, additional, Ghalli, Farid, additional, Lawman, Sarah, additional, Sinha, Smeeta, additional, Chrysochou, Constantina, additional, Chukwu, Chukwuma, additional, Maire De Bhailis, Aine, additional, Al Chalabi, Saif, additional, Hudson, Amy, additional, Gopu, Arun, additional, Wickens, Olivia, additional, Storrar, Joshua, additional, Wahba, Mona, additional, Lorde, Nathan, additional, Rony, Mohammad, additional, Griffin, Sian, additional, Latif, Farah, additional, Ali, Mohammad, additional, DaSilva, Louise, additional, Ayling-Smith, Jonathan, additional, Mahdi, Eamon, additional, Willcocks, Lisa, additional, Jones, Rachel, additional, Cheung, Chee Kay, additional, Selvaskandan, Haresh, additional, Pugh, Dan, additional, Sayer, Matthew, additional, Dhaun, Neeraj, additional, Chapman, Fiona, additional, Mark, Patrick, additional, Geddes, Colin, additional, McQuarrie, Emily, additional, Patel, Rajan, additional, Solomon, Laurence, additional, Ponnusamy, Arvind, additional, Morris, Adam, additional, Okoh, Pedro, additional, Floyd, Lauren, additional, Dhaygude, Ajay, additional, Leung, Janson, additional, Goldsmith, Christopher, additional, Pandya, Bhavna, additional, Tez, Didem, additional, Mikhail, Ashraf, additional, Brown, Karen, additional, Bucknall, Thomas, additional, Lambie, Mark, additional, Comunale, Roderick, additional, Brandon, Donald, additional, Martinez, Stacy, additional, Hall, Amanda, additional, Henderson, Amy, additional, Fearday, Aaron, additional, Douthit, Nicole, additional, Snow, Brian, additional, Silva, Arnold, additional, Sly, Cathylee, additional, Keller, Christopher, additional, Davidson, Robert, additional, Meng, Jerry, additional, Haws, Robert, additional, Kattamanchi, Siddhartha, additional, Mojarrab, Javad, additional, Pillai, Unnikrishnan, additional, Lafayette, Richard, additional, O'Shaughnessy, Michelle, additional, Kamal, Fahameedah, additional, Mehta, Kshama, additional, Baker, Bruce, additional, Ruiz, Mario, additional, Jyothinagaram, Praveena, additional, Peri, Usha, additional, Paxton, William, additional, Tumlin, James, additional, McGreal, Kerri, additional, McCarthy, Ellen, additional, Kimber, Cassandra, additional, Gautam, Archana, additional, Khalil, Kassem, additional, Nguyen, Viet, additional, Minasian, Raffi, additional, Arfaania, Dariush, additional, Daneshvari, Sam, additional, Zakari, Michel, additional, Patrikyan, Artashes, additional, Afsari, Rouzbeh, additional, Ayvazyan, Christine, additional, Fakih, Faisal, additional, Lagatta, Mark, additional, Rodriguez, Alfred, additional, Avella, Jorge Enrique Monroy, additional, Patak, Ramachandra, additional, Kadakia, Jigar, additional, Appel, Gerald, additional, Ahn, Wooin, additional, Nelson, Bradley, additional, Medina, Allyson, additional, Ahmad, Syeda, additional, Peleg, Yonatan, additional, Clement, Nisha, additional, Chiu, Ian, additional, Hendren, Elizabeth, additional, Bomback, Andrew, additional, Canetta, Pietro, additional, Spinowitz, Bruce, additional, Charytan, Chaim, additional, Parikh, Nishita, additional, Kuo, Sheng, additional, Raichoudhury, Ritesh, additional, Dobre, Mirela, additional, Negrea, Lavinia, additional, Padiyar, Aparna, additional, Jittirat, Arksarapuk, additional, Pradhan, Nishigandha, additional, Dhelaria, Ranjit, additional, Balamuthusamy, Saravanan, additional, Madhrira, Machaiah, additional, Powell, Thomas, additional, Lifland, Howard, additional, Bailey, Asha, additional, Ford Sightler, Sarah Ashley, additional, Suthar, Meera Patel, additional, Green, Heather, additional, Parikh, Samir, additional, Ayoub, Isabelle, additional, Almaani, Salem, additional, Contreras, Gabriel, additional, Fornoni, Alessia, additional, Drexler, Yelena, additional, Geara, Abdallah, additional, Sheridan, Brittany, additional, Coppock, Gaia, additional, Hogan, Jonathan, additional, Gonzalez, Carlos, additional, Bhadra, Shamik, additional, Chowdhury, Pradip, additional, Kyaw, Kay, additional, Tan, May, additional, Raakesh, Lathika, additional, Mendoza, Elder, additional, Viramontes, Veronica, additional, Chaudhry, Asghar, additional, Carbonell, Juan, additional, Gadh, Rajdeep, additional, Fernandez, Victor, additional, Kassem, Mohamad, additional, Jacob, Radu, additional, Wilder, Karen, additional, Newsome, Britt, additional, Klamm, Kathryn, additional, Suyumova, Irina, additional, Kooienga, Laura Ann, additional, Janko, Catherine, additional, Rizk, Dana, additional, Julian, Bruce, additional, Caster, Dawn, additional, Perez, Erika, additional, Garg, Gunjan, additional, Gowda, Nayan, additional, Udani, Suneel, additional, Mandayam, Sreedhar, additional, Workeneh, Biruh, additional, Assefi, Ali, additional, Greco, Barbara, additional, Germain, Michael, additional, Patel, Jusmin, additional, Quinn, Sarah, additional, Sullivan, James, additional, Glaze, Jeffrey, additional, Madonia, Phillip, additional, McMahon, Kellyn, additional, Giles, Harold, additional, Adler, Sharon, additional, and Dai, Tiane, additional

Published
2023
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12. Red Flags Not To Be Missed

Author

Navarro, David, Fonseca, Nuno Moreira, Ferreira, Ana Carina, Barata, Rui, Góis, Mário, Viana, Helena, Nolasco, Fernando, and NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)

Subjects
Microscopy, Kidney/pathology, Biopsy, Necrosis/pathology, Humans, Kidney Diseases, Emblems and Insignia, Lipids, Retrospective Studies
Abstract

BACKGROUND: Urinary sediment is a noninvasive laboratory test that can be performed by an automated analyzer or manually by trained personnel. Manual examination remains the diagnostic standard because it excels at differentiating isomorphic from dysmorphic red blood cells and identifying other urinary particles such as renal tubular epithelial cells (RTECs), lipids, crystals, and the composition of casts. This study aimed to investigate the prevalence of a complete profile of urinary sediment particles and its associations with histologic lesions on kidney biopsy, regardless of diagnosis. METHODS: This was a single-center, observational retrospective study of 131 patients who had contemporary manual urinary sediment evaluation and kidney biopsy. A comprehensive set of urinary particles and histologic lesions were quantified, and their associations were analyzed. RESULTS: In our samples, we found an elevated frequency of findings suggestive of proliferative kidney disease and a low frequency of particles evoking urologic damage. The association of histologic lesions and urinary particles was explored with a multivariate model. We identified urinary sediment characteristics that independently correlated with the presence of some histologic lesions: urinary lipids with mesangial expansion (OR=2.86; 95% confidence interval [95% CI], 1.3 to 6.3), mesangial hypercellularity (OR=2.44; 95% CI, 1.06 to 5.58), and wire loops and/or hyaline deposits (OR=2.89; 95% CI, 1.13 to 7.73); Urinary renal tubular epithelial cells with endocapillary hypercellularity (OR=3.17; 95% CI, 1.36 to 7.39), neutrophils and/or karyorrhexis (OR=4.51; 95% CI, 1.61 to 12.61), fibrinoid necrosis (OR=4.35; 95% CI, 1.48 to 12.74), cellular/fibrocellular crescents (OR=5.27; 95% CI, 1.95 to 14.26), and acute tubular necrosis (OR=2.31; 95% CI, 1.08 to 4.97). CONCLUSIONS: In a population of patients submitted to kidney biopsy, we found that the presence of some urinary particles (renal tubular epithelial cells, lipids, and dysmorphic erythrocytes), which are seldom reported by automated analyzers, is associated with active proliferative histologic lesions. In this regard, manual urinary sediment evaluation may help to shape the indications for performing a kidney biopsy. publishersversion published

Published
2023

13. Performance of the ACMG-AMP criteria in a large familial renal glucosuria cohort with identified SLC5A2 sequence variants

Author

Barata, Rui, Fila, Marc, Dalla-Vale, Fabienne, Bogarin, Roberto, Nunes, Paula, JS, Ramalho, Rueff, José, Calado, Joaquim, NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), iNOVA4Health - pólo NMS, and Centre for Toxicogenomics and Human Health (ToxOmics)

Subjects
glycosuria, proximal tubule, sodium glucose transporter 2, Genetics, renal, Genetics(clinical)
Abstract

Funding Information: This work was supported by grant UID/BIM/00009/2016, Portuguese Science and Technology Foundation. Publisher Copyright: © 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. Familial Renal Glucosuria (FRG) is a co-dominantly inherited trait characterized by orthoglycaemic glucosuria. From 2003 to 2015 we have reported several cohorts validating SLC5A2 (16p11.2), encoding SGLT2 (Na+/glucose cotransporter family member 2), as the gene responsible for FRG. The aim of this work was to validate the variants identified in our extended FRG cohort of published, as well more recent unreported cases, according to the ACMG-AMP 2015 criteria. Forty-six variants were evaluated, including 16 novel alleles first described in this study. All are rare, ultra-rare or absent from population databases and most are missense changes. According to the ACMG-AMP standards, only 74% of the variants were classified as P/LP. The lack of descriptions of unrelated patients with similar variants or failing to test additional affected family members, averted a conclusion for pathogenicity in the alleles that scored VUS, highlighting the importance of both family testing and variant reporting. Finally, the cryo-EM structure of the hSGLT2–MAP17 complex in the empagliflozin-bound state improved the ACMG-AMP pathogenicity score by identifying critical/functional protein domains. publishersversion inpress

Published
2023

23. Acute interstitial nephritis due to dolutegravir: The first case reported.

Author

Barata, Rui, Marques da Costa, Bernardo, Navarro, David, Mendes, Marco, Silva, Cecília, Góis, Mário, Sousa, Helena, and Nolasco, Fernando

Abstract

Copyright of Nefrologia is the property of Revista Nefrologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
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28. Acute Kidney Injury in the Context of Inflammatory Bowel Disease - A Clinical Case

Author

Ribeiro Francisco, Sousa Helena, Cotovio Patrícia, Nolasco Fernando, Barata Rui, Garcia Joana Lemos, Marques Joana Cristóvão, Navarro David, and Góis Mário

Subjects
medicine.medical_specialty, business.industry, Acute kidney injury, Context (language use), HCC NEF, IgA nephropathy, medicine.disease, Inflammatory bowel disease, Gastroenterology, Internal medicine, medicine, Tubulointerstitial nephritis, Clinical case, kidney injury/acute, HCC PAT CLIN, Mesalazine, business
Abstract

Extraintestinal manifestations of inflammatory bowel disease are common and extendable to all organs. Kidney and lower genitourinary system occurs in 4-23% of cases. This may be dependent on inflammatory bowel disease activity, secondary to metabolic disorders, drugs or others. We present a case of a 68-year-old man with ulcerative colitis for 22 years admitted in our department for acute nephritic syndrome. Urinary microscopy suggested glomerular injury. A kidney biopsy was performed and was compatible with acute interstitial nephritis and IgA nephropathy. Toxicity of mesalazine and glomerulonephritis secondary to ulcerative colitis were assumed. The patient suspended mesalazine and started prednisolone with clinical improvement. Our purpose is to sensitize the importance of having a prompt and thorough evaluation of acute kidney injury in patients with inflammatory bowel disease. We briefly review the broad spectrum of kidney manifestations in this population, focusing on mesalazine-induced nephrotoxicity. info:eu-repo/semantics/publishedVersion

Published
2021

36. Gás Natural Liquefeito – GNL/LNG Um combustível alternativo no transporte marítimo

Author

Barata, Rui Manuel Martins, Sousa, João Figueira de, and Gonçalves, Fernando Cruz

Subjects
Gás, Gás natural, GNL, Bancas, Abastecimento, Porto de Lisboa, Engenharia e Tecnologia [Domínio/Área Científica]
Abstract

O progresso tem permitido o desenvolvimento do transporte marítimo por todo o mundo e consequentemente, isso reflete-se num aumento do número de navios a navegar por todo o planeta. O ritmo crescente de navios, aliado ao controlo dos custos de operação e da pressão de cumprir com a programação das estadias nos portos, faz com que, se descuidem muitas vezes os aspetos relativos ao respeito pelo ambiente. Muitos destes navios têm mais de 30 anos, tendo sofrido ao longo do tempo diversos mecanismos de deterioração, evidenciando as mais variadas anomalias e utilizando combustíveis fósseis altamente poluentes como é o caso do fuel. Neste contexto, em que armadores e operadores, são expostos a uma pressão económica para a redução de custos, associada à ausência de uma visão ambiental, tem sido a sociedade civil e a comunidade científica a pressionar as instituições oficiais a tomarem ações de regulamentação que forcem a alteração do paradigma associado ao transporte marítimo. Neste contexto da necessidade de garantir a sustentabilidade ambiental, felizmente, a pressão da sociedade tem tido algum sucesso e assim armadores e operadores têm sido confrontados com legislação que os força a investir na procura de soluções menos agressivas para o ambiente. O estado da arte tecnológica dos nossos dias já torna o GNL1 uma opção viável como combustível alternativo para o transporte marítimo. Na presente data existem mais de 120 navios movidos com este combustível por todo o mundo e um número semelhante em ordens de novas construções. Para manter este progresso é necessário garantir condições de abastecimento deste novo combustível aos navios, garantindo a autonomia dos mesmos, e adotando procedimentos de operação em segurança que salvaguarde pessoas e bens. O Porto de Lisboa tem uma posição natural que o torna um porto geostratégico com grande potencial para ser um centro de abastecimento de bancas de GNL de excelência, a nível europeu, bastando para tal haver investimento em formação de técnicos e infraestruturas de suporte.

Published
2018

39. Do mar à cidade

Author

Barata, Rui Miguel Charnock and Pernão, João Nuno de Carvalho

Subjects
Frente ribeirinha, Pólo maritmo, Pedroços dock, Doca de Pedrouços, Maritime centre, Urban requalification, Lisbon wterfront, Requalificação urbana
Abstract

Dissertação de Mestrado Integrado em Arquitetura, com a especialização em Arquitetura, apresentada na Faculdade de Arquitetura da Universidade de Lisboa para obtenção do grau de Mestre. Depois do mar, chegamos a Lisboa de barco. Em silêncio atracamos à margem árida. O comboio passa e desenha um muro vedado. Deste lado ninguém nos recebe, nem vê chegar – do outro, a cidade de Lisboa. Consequente da linha de comboio que separa Lisboa da sua margem com o rio Tejo, ainda se verifica o isolamento e degradação de certas partes da frente ribeirinha. O presente trabalho pretende contribuir para o casamento entre o mar e a cidade, e ligar a área de Pedrouços ao território ribeirinho e cidade de Lisboa. O projecto trata a requalificação e renovação urbana do aterro portuário pós-industrial de Pedrouços, antiga “Doca Pesca”. O tema “Do Mar à Cidade” surge da experiência de chegada do mar à cidade. Pretende-se abordar a requalificação de um porto e territórios costeiros tendo em conta essa perspectiva. Propõe-se a reconversão da formal doca de pesca em doca de recreio, um pólo marítimo – equipamento de apoio ao desporto e recreio marítimo – e a manutenção do estaleiro de vela de recreio existente. Paralelo ao programa de índole náutico, projecta-se habitação, restaurantes, jardins, e um parque que se espelha aos jardins de Algés – tendo por eixo de simetria a linha férrea – e redesenha-se o limite das praias de Pedrouços e Algés, procurando a repristinação do seu território. Apresenta-se um projecto que, concretiza a ligação ribeirinha entre Belém e Algés, apresenta uma margem do rio Tejo aos habitantes da sua proximidade, assim como à população que aí procurará o seu espaço de trabalho, habitação e de lazer, e recebe quem chega do mar à cidade de Lisboa. ABSTRACT : With the sea behind us, we approach Lisbon by boat. Silently, we make port on the arid dock. The train passes by and creates a barrier. On this side of the railway line no one greets us or acknowledges our arrival – on the other side, lies the city of Lisbon. As a result of the railway line that separates Lisbon from its river Tagus, decay and isolation still characterize parts of Lisbon´s waterfront. The present work aims to contribute to the connection between the city and the sea, and unify the Pedrouços area with Lisbon city and the waterfront. The project comprises the requalification and urban renovation of the post-industrial dock of Pedrouços, formerly the “Doca Pesca”. The subject “Do Mar à Cidade” which translates to “From the Sea to the City”, derives from the experience of arriving at the city by sea, and its application to the subject of requalifying a waterfront and its ports. The project is defined by the reconversion of the former fishing dock into a recreational dock, a maritime centre for nautical sport and recreational activities, and the integration of the existing shipyard. In addition, the project includes housing, restaurants, gardens, and a park which runs symmetrical to the Algés gardens – with the railway line as the axis – and we redefine the border that characterizes the beaches of Pedrouços and Algés, thus achieving its repristination. The project will reconnect the areas of Belém and Algés, and open this particular part of the city´s waterfront to its inhabitants who will the able to choose the location as a place to live, work and play, welcoming those who approach Lisbon by sea. N/A

Published
2017

41. Interação de iões metálicos e 8-hidroxi- 5-sulfoxiquinolina com surfactantes e polieletrólitos conjugados em solução

Author

Barata, Rui Pedro Rodrigues de Morais, Burrows, Hugh, Ramos, Maria Luísa, and Costa, Telma

Subjects
Ambiente, Iões metálicos, Química, Controle de qualidade e ambiente, Polielectrólitos
Abstract

Dissertação de Mestrado em Química apresentada à Faculdade de Ciências e Tecnologia da Universidade de Coimbra. Atualmente, uma área de interesse crescente, é o desenvolvimento de compostos que respondam seletivamente a iões metálicos, com potencial aplicação em dispositivos optoeletrónicos (OLEDs), sensores, díodos emissores de luz (LEDs) e em sistemas fotovoltaicos de conversão de energia. Neste trabalho, estudou-se a interação da 8-Hidroxi-5-Sulfoxiquinolina (8-HQS) com quatro iões metálicos (Mn+= Ga3+, In3+, Zn2+ e Al3+) a qual revelou a formação de complexos aniónicos de diferentes estequiometrias. Estes complexos promovem alterações significativas nas propriedades fotofísicas da 8-HQS. A adição de surfactantes catiónicos, como o brometo de cetiltrimetialamónio (CTAB) e o brometo dodeciltrimetialamónio (DTAB), e de gemini dicatiónico, como o dibrometo de hexanodiil- α, ω-bis(dodecildimetilamónio) (gemini 12-6-12), resultam num aumento do rendimento quântico de fluorescência dos complexos metálicos. No caso do gemini observou-se, embora a experiência não tenha sido realizada nas condições ideais, que no sistema 8- HQS/Al3+ pode existir interação com o gemini acompanhadas por mudanças conformacionais. No DTAB e no CTAB verificou-se que há um aumento da concentração do complexo 1:2 [In(HQS)2]-, relativamente ao complexo 1:3, [In(HQS)3]3- ou, muito provavelmente, uma alteração da dinâmica de troca entre os dois complexos. Foi ainda estudada a possibilidade de transferência de energia de um polieletrólito conjugado, brometo de poli{[9,9-bis(6’-N,N,N-trimetilamónio) hexil]fluoreno-fenileno} (HTMA-PFP), para os complexos metálicos, 8-HQS:Mn+. A eficiência deste processo depende do metal, assim como do solvente utilizado. Por fim, estudou-se a interação do ião uranilo (UO2 2+) com a 8-HQS, onde se observou o efeito da adição da 8-HQS a uma solução uranilo, e o efeito da adição de ião uranilo a uma solução de 8-HQS. Verificou-se que existe a formação de um complexo não fluorescente com estequiometria de duas moléculas de 8-HQS para uma de uranilo. Estes estudos foram realizados recorrendo a técnicas de Espectroscopia de Absorção UV/Vis, Fluorescência de Estado Estacionário e de Estado Dinâmico, Flash Photolysis e Espectroscopia de Ressonância Magnética Nuclear (RMN de 1H e 13C). A combinação de todas estas técnicas permitiu uma caracterização estrutural e pormenorizada destes sistemas.

Published
2016

42. Hemangioma cavernoso : o papel da ecografia

Author

Barata, Rui Francisco Furtado Dias, 1992 and Pinto, Filomena

Subjects
Oftalmologia, Ultrassonografia, Órbita, Ciências Médicas [Domínio/Área Científica], Hemangioma cavernoso
Abstract

Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2016 Submitted by Biblioteca da Faculdade de Medicina da Universidade de Lisboa (repositorio@medicina.ulisboa.pt) on 2017-07-18T12:19:45Z No. of bitstreams: 1 RuiFBarata.pdf: 1173364 bytes, checksum: 3858a31e344fadbb84711940718bea3d (MD5) Made available in DSpace on 2017-10-26T14:01:32Z (GMT). No. of bitstreams: 1 RuiFBarata.pdf: 1173364 bytes, checksum: 3858a31e344fadbb84711940718bea3d (MD5) Previous issue date: 2016

Published
2016

44. Políticas de integração de alunos que têm o português como língua não materna Projeto de Intervenção Contributo para a integração dos alunos de PLNM no 1ºCiclo

Author

Barata, Rui Miguel Leitão and Almeida, Ana Patrícia

Subjects
Português Língua Não Materna, Português como língua de acolhimento, Perfis Linguísticos, Portuguese as a second language, Bilingue, Portuguese as the host language, Alunos estrangeiros, Not Maternal Portuguese Language, Foreign students, Unilingue, Monolingual, Integration policies / host and Immigration and levels of language proficiency, Profiles Language, Bilingual, Políticas Educativas, Políticas de integração e Imigração, Educational Policies
Abstract

As mudanças ocorridas na sociedade portuguesa, nas últimas décadas, colocam às escolas desafios constantes. Num esforço suplementar, estas instituições procuram fazer da diversidade cultural um fator de coesão e de integração. Cada vez mais o PLNM1 faz parte do quotidiano de algumas escolas do nosso país e como tal, o fator integração revela-se não só como um agente de inclusão, bem como agente de grande influência no sucesso educativo dos alunos em que o português não é a sua língua materna. Este trabalho de projeto procura ir ao encontro de uma necessidade pedagógica, sentida pelo corpo docente do agrupamento horizontal X, no que concerne a processos e mecanismos de integração de alunos estrangeiros nas escolas do 1ºCEB2. Tendo por base a análise dos questionários dos docentes do agrupamento de escolas X, no que respeita à integração dos alunos, formação e práticas pedagógicas ao nível do PLNM, foi concebido este projeto. Em boa verdade, visa sugerir propostas de atividades, não apenas na integração dos alunos que têm o PLNM, mas também ir de encontro às necessidades de formação dos professores e práticas pedagógicas ou a outros problemas, parcelares, identificados a partir do diagnóstico. Optou-se, desta forma, por uma metodologia de trabalho de projeto de natureza qualitativa, dividido em duas grandes fases: a primeira fase, de diagnóstico, que consistiu na aplicação de um questionário a todos os docentes do agrupamento e numa análise documental; a segunda fase, decorrente da análise dos dados recolhidos através do diagnóstico, composta pela conceção de um projeto que permitisse dar resposta aos problemas identificados na fase anterior. Após a análise dos resultados obtidos, tornou-se fulcral conceber um projeto que fosse ao encontro à questão de partida: Que políticas educativas e que atividades adotar no agrupamento X, de forma a integrar os alunos que têm o PLNM? The changes in Portuguese society in recent decades, pose constant challenges to schools. In an additional effort, these institutions seek to make cultural diversity a factor of cohesion and integration. Increasingly PLNM3 is part of everyday life for some schools of our country and as such, the integration factor reveals itself not only as an agent of inclusion, as well as an agent of great influence on the educational success of students in which Portuguese is not their mother language. This research project seeks to meet an educational need, felt by the teaching staff of the horizontal group X, in what concerns the processes and mechanisms of integration of foreign students in elementary school. This project was conceived based on the analysis of questionnaires from teachers in school group X, as regards the integration of students, training and teaching practices at the level of PLNM. This assignment, seeks to suggest proposals for activities not only having in mind the integration of students who have PLNM, but also meet the education needs of teachers and teaching practices or other individual problems, identified from the diagnosis. It was decided, therefore, a methodology for design work of a qualitative nature, divided into two phases: the first stage of diagnosis, which consisted of a questionnaire to all teachers in the group and document analysis, the second phase, resulting from analysis of data collected through the diagnosis, made by creating a project that would allow to address the problems identified in the previous phase. After analyzing the results, it became crucial to design a project that would meet the initial question: What educational policies and activities should group X take, in order to integrate students who have PLNM?

Published
2012

46. A pilot program for patient involvement in interdialytic weight gain management in dialysis patients.

Author

Fonseca, Nuno Moreira, Gaspar, Ana, Barata, Rui, Sousa, Henrique Silva, Silva, Susana, and Branco, Patrícia

Subjects
WEIGHT gain, HEMODIALYSIS patients, REGULATION of body weight, NUTRITION counseling, HYPERTENSION, HEALTH self-care, PREVENTIVE medicine
Abstract

Higher interdialytic weight gain (IDWG) is associated with higher predialysis blood pressure, worse nutritional status and increased mortality. The aim of pilot program is to involve patients in the management of their IDWG in order to obtain better outcomes. Our pilot program will be based in two simultaneous approaches: Firstly, patients will be given a chart to fill out at the beginning of each dialysis session to register whether they have managed to keep their IDGW below their personalized target. Secondly, professional dietary counseling will be reinforced for those who present lower IDWG compliance on a monthly basis. Outcomes will be measured according to IDWG control, predialytic blood pressure control and nutritional status at 3 months. These parameters will be compared with to data form the previous trimester. All patients currently undergoing hemodialysis at our clinic (n=50) will be included. This program will be carried out by our hemodialysis clinical team including physicians, nurses and nutritionists. Our integrative approach aims for the delivery of person-centered, high-quality care, by empowering our patients to attain better health outcomes with their direct participation. [ABSTRACT FROM AUTHOR]

Published
2019
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47. A pilot program of integration of preventive foot care into comprehensive care of diabetic hemodialysis patients.

Author

Fonseca, Nuno Moreira, Barata, Rui, Gaspar, Ana, Sousa, Henrique Silva, Silva, Susana, Costa, Ana Luísa, Boavida, José Manuel, Raposo, João, and Branco, Patrícia

Subjects
*PODIATRISTS, *FOOT care, *HEMODIALYSIS patients, *DIABETIC foot, *PERIPHERAL vascular diseases, *FOOT ulcers
Abstract

Diabetes mellitus is a common endocrine disorder known for its multifaceted complications, including diabetic foot ulcers which often result in amputation. Foot ulcer disease poses a therapeutic challenge as concomitant infection is frequently present, making it a leading cause of diabetes-related hospital admission. Renal patients on hemodialysis often present advanced peripheral artery disease, which also increases the risk of foot ulcer disease. Our hemodialysis clinic provides renal care exclusively to diabetic patients. While most hemodialysis centers provide comprehensive care to renal patients that extends beyond hemodialytic treatment, such as nutritional guidance or social support, dedicated care to address foot care is generally lacking. Our patients complex health needs often require visits to multiple providers, which can be challenging for patients in the absence of coordinated care. Given the particularly dire impact of diabetic ulcer disease on patients' morbidity and quality of life, we have decided to improve patients' care coordination by implementing a preventive foot care program at our hemodialysis clinic. Our pilot program will be based in two simultaneous approaches: Patients, families and caretakers, will be provided with inhouse educational sessions on foot care and preventive strategies for ulcerative disease. In addition to patient empowerment, monthly active surveillance of ulcerative disease will be provided in cooperation with an external podology clinic dedicated to diabetic patients. Outcomes will be measured by incidence of foot ulcers, antibiotic use, amputations, hospitalizations, and related mortality. All patients currently undergoing hemodialysis at our clinic (n=50) will be included. This program will be carried out by our hemodialysis clinical team jointly with a podology clinic specialized in diabetic foot care. Educational one-hour sessions on 'preventive foot care' will be provided to patients and family or caretakers in smalls groups of 8-10 people. Patients will be actively assessed on a monthly basis at the podology clinic. Our joint podology-nephrology program is a commitment to the delivery of person-centered, highquality care that aims to improve health outcomes, by reducing the incidence of underlying disease complications, hospital admission, as well as a mortality. [ABSTRACT FROM AUTHOR]

Published
2019
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48. Urinary Sediment Microscopy and Correlations with Kidney Biopsy: Red Flags Not To Be Missed.

Author

Navarro D, Fonseca NM, Ferreira AC, Barata R, Góis M, Sousa H, and Nolasco F

Subjects
Humans, Biopsy, Kidney pathology, Lipids, Microscopy, Necrosis pathology, Retrospective Studies, Kidney Diseases
Abstract

Background: Urinary sediment is a noninvasive laboratory test that can be performed by an automated analyzer or manually by trained personnel. Manual examination remains the diagnostic standard because it excels at differentiating isomorphic from dysmorphic red blood cells and identifying other urinary particles such as renal tubular epithelial cells (RTECs), lipids, crystals, and the composition of casts. This study aimed to investigate the prevalence of a complete profile of urinary sediment particles and its associations with histologic lesions on kidney biopsy, regardless of diagnosis., Methods: This was a single-center, observational retrospective study of 131 patients who had contemporary manual urinary sediment evaluation and kidney biopsy. A comprehensive set of urinary particles and histologic lesions were quantified, and their associations were analyzed., Results: In our samples, we found an elevated frequency of findings suggestive of proliferative kidney disease and a low frequency of particles evoking urologic damage. The association of histologic lesions and urinary particles was explored with a multivariate model. We identified urinary sediment characteristics that independently correlated with the presence of some histologic lesions: urinary lipids with mesangial expansion (OR=2.86; 95% confidence interval [95% CI], 1.3 to 6.3), mesangial hypercellularity (OR=2.44; 95% CI, 1.06 to 5.58), and wire loops and/or hyaline deposits (OR=2.89; 95% CI, 1.13 to 7.73); Urinary renal tubular epithelial cells with endocapillary hypercellularity (OR=3.17; 95% CI, 1.36 to 7.39), neutrophils and/or karyorrhexis (OR=4.51; 95% CI, 1.61 to 12.61), fibrinoid necrosis (OR=4.35; 95% CI, 1.48 to 12.74), cellular/fibrocellular crescents (OR=5.27; 95% CI, 1.95 to 14.26), and acute tubular necrosis (OR=2.31; 95% CI, 1.08 to 4.97)., Conclusions: In a population of patients submitted to kidney biopsy, we found that the presence of some urinary particles (renal tubular epithelial cells, lipids, and dysmorphic erythrocytes), which are seldom reported by automated analyzers, is associated with active proliferative histologic lesions. In this regard, manual urinary sediment evaluation may help to shape the indications for performing a kidney biopsy., (Copyright © 2022 by the American Society of Nephrology.)

Published
2023
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49. Ulcerating stasis dermatitis of the forearm associated with arteriovenous graft and central vein stenosis.

Author

Guimarães DA, Ribeiro LM, Barata R, Mendes MM, Mendes M, and Mouzinho MM

Subjects
Constriction, Pathologic, Forearm blood supply, Humans, Male, Middle Aged, Ulcer, Upper Extremity, Arteriovenous Shunt, Surgical adverse effects, Dermatitis, Skin Ulcer
Abstract

Introduction: Stasis dermatitis is a pathologic condition of the skin that most commonly occurs in the lower limb, where it is caused by chronic venous insufficiency. Stasis dermatitis of the upper limb is rare., Case Report: A 45-year-old male, resident in Angola, presented to the emergency department with an ulcer encompassing the entire left forearm. Past medical history comprised arterial hypertension and end stage renal disease treated with hemodialysis. Dialysis access consisted of a left brachial-basilic AV graft obtained 4 years before. The patient also reported that a right internal jugular vein catheter was used previously during the maturation of the left brachial-basilic AV graft. Stenosis of the left brachiocephalic vein was documented at angiography. Angioplasty was performed, with complete resolution of the wound 2 months after admission., Conclusion: The differential diagnosis of extensive ulcer of the forearm must include neoplasms, cellulitis, and/or deep tissue infection with secondary ulceration, but it is also important to maintain suspicion for venous stasis syndrome as a rare but possible cause of these lesions.

Published
2022
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