943 results on '"Barbier, F"'
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2. Instrumentation of the Concept II ergometer for optimization of the gesture of the rower
- Author
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Pudlo, P., primary, Barbier, F., additional, and Angue, J. C., additional
- Published
- 2020
- Full Text
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3. French hospital discharge database (PMSI) and bacterial resistance: Is coding adapted to hospital epidemiology?
- Author
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de Léotoing, L., Barbier, F., Dinh, A., Breilh, D., Chaize, G., Vainchtock, A., Levy-Bachelot, L., Bensoussan, C., Dramard, S., and Fernandes, J.
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- 2018
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4. Détection de virus respiratoire par PCR multiplexe nasopharyngée dans l'insuffisance respiratoire aiguë des patients immunodéprimés
- Author
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Maillard, A., primary, Goff, J. Le, additional, Barry, M., additional, Lemiale, V., additional, Demoule, A., additional, Barbier, F., additional, Pène, F., additional, Salmona, M., additional, Mokart, D., additional, and Azoulay, E., additional
- Published
- 2023
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5. Défaillance rénale chez le patient infecté par le VIH
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Bretagnol, A. and Barbier, F.
- Abstract
La défaillance rénale est fréquente chez les patients infectés par le virus de l’immunodéficience humaine (VIH) hospitalisés en réanimation. L’amélioration de l’espérance de vie des malades traités par antirétroviraux (ARV) est associée à une prévalence croissante de l’insuffisance rénale chronique (IRC) dans cette population, compte tenu d’une exposition plus fréquente et plus prolongée aux comorbidités à risque rénal (notamment hépatiques et cardiovasculaires) et de la néphrotoxicité tardive de certains ARV. L’incidence de l’HIV-associated nephropathy(HIVAN) et des autres atteintes rénales directement liées au VIH ou au syndrome d’immunodéficience acquise (SIDA) tend parallèlement à diminuer. Par ailleurs, la survenue d’une insuffisance rénale aiguë (IRA) à l’admission ou au cours du séjour concerne un à deux tiers des patients et augmente significativement le risque de décès en réanimation et d’évolution ultérieure vers l’IRC. Le sepsis et l’administration de médicaments néphrotoxiques sont les principales causes d’IRA dans ce contexte. La ponction-biopsie rénale doit être discutée en cas d’IRA organique sans étiologie confirmée par méthodes non invasives, en particulier lorsque le tableau est évocateur de néphropathie glomérulaire. Enfin, en l’absence de données, la gestion des ARV reste problématique chez les patients de réanimation avec fonction rénale instable: cet aspect essentiel de la prise en charge doit faire l’objet de travaux prospectifs spécifiques. Renal failure is common in human immunodeficiency virus (HIV)-infected patients admitted to the intensive care unit (ICU). Improved life expectancy in patients receiving combination antiretroviral therapy (cART) is associated with an increasing prevalence of chronic kidney diseases (CKD) in this population, as a result of extended exposure to comorbidities that may impair renal function (including hepatic and cardiovascular diseases) and late nephrotoxic effects of certain cART regimen. Meanwhile, a decreasing trend is observed in the incidence of HIV-associated nephropathy (HIVAN) and other kidney diseases directly related to HIV infection or the acquired immunodeficiency syndrome. Acute renal failure (ARF) is present upon admission or occurs during the ICU stay in one to two-thirds of patients, and significantly increases the risk of ICU death and subsequent progression to CKD. Sepsis and exposure to nephrotoxic drugs are the main causes of ARF in this context. Renal biopsy should be discussed in each ARF episode when noninvasive methods failed to identify the underlying nephropathy. Lastly, since published data are dramatically lacking, the management of cART remains challenging in critically ill patients with altered renal function. This crucial aspect of intensive care in HIV-infected patients should be the focus of further prospective works.
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- 2024
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6. Influence des chaussures minimalistes sur le risque de blessures de sur-sollicitation du membre inférieur chez l’enfant
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Herbaut, A., Roux, M., Guéguen, N., Barbier, F., Simoneau-Buessinger, E., Chavet, P., and Rozenblat, M.
- Published
- 2017
- Full Text
- View/download PDF
7. Long-term (180-day) outcomes in critically ill patients with COVID-19 in the REMAP-CAP randomized clinical trial
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Florescu, S, Stanciu, D, Zaharia, M, Kosa, A, Codreanu, D, Kidwai, A, Masood, S, Kaye, C, Coutts, A, MacKay, L, Summers, C, Polgarova, P, Farahi, N, Fox, E, McWilliam, S, Hawcutt, D, Rad, L, O’Malley, L, Whitbread, J, Jones, D, Dore, R, Saunderson, P, Kelsall, O, Cowley, N, Wild, L, Thrush, J, Wood, H, Austin, K, Bélteczki, J, Magyar, I, Fazekas, Á, Kovács, S, Szőke, V, Donnelly, A, Kelly, M, Smyth, N, O’Kane, S, McClintock, D, Warnock, M, Campbell, R, McCallion, E, Azaiz, A, Charron, C, Godement, M, Geri, G, Vieillard-Baron, A, Johnson, P, McKenna, S, Hanley, J, Currie, A, Allen, B, McGoldrick, C, McMaster, M, Mani, A, Mathew, M, Kandeepan, R, Vignesh, C, TV, B, Ramakrishnan, N, James, A, Elvira, E, Jayakumar, D, Pratheema, R, Babu, S, Ebenezer, R, Krishnaoorthy, S, Ranganathan, L, Ganesan, M, Shree, M, Guilder, E, Butler, M, Cowdrey, K-A, Robertson, M, Ali, F, McMahon, E, Duffy, E, Chen, Y, Simmonds, C, McConnochie, R, O’Connor, C, El-Khawas, K, Richardson, A, Hill, D, Commons, R, Abdelkharim, H, Saxena, M, Muteithia, M, Dobell-Brown, K, Jha, R, Kalogirou, M, Ellis, C, Krishnamurthy, V, O’Connor, A, Thurairatnam, S, Mukherjee, D, Kaliappan, A, Vertue, M, Nicholson, A, Riches, J, Maloney, G, Kittridge, L, Solesbury, A, Ramos, A, Collins, D, Brickell, K, Reid, L, Smyth, M, Breen, P, Spain, S, Curley, G, McEvoy, N, Geoghegan, P, Clarke, J, Silversides, J, McGuigan, P, Ward, K, O’Neill, A, Finn, S, Wright, C, Green, J, Collins, É, Knott, C, Smith, J, Boschert, C, Slieker, K, Ewalds, E, Sanders, A, Wittenberg, W, Geurts, H, Poojara, L, Sara, T, Nand, K, Reeve, B, Dechert, W, Phillips, B, Oritz-Ruiz de Gordoa, L, Affleck, J, Shaikh, A, Murray, A, Ramanan, M, Frakking, T, Pinnell, J, Robinson, M, Gledhill, L, Wood, T, Sanghavi, R, Bhonagiri, D, Ford, M, Parikh, HG, Avard, B, Nourse, M, McDonald, B, Edmunds, N, Hoiting, O, Peters, M, Rengers, E, Evers, M, Prinssen, A, Morgan, M, Cole, J, Hill, H, Davies, M, Williams, A, Thomas, E, Davies, R, Wise, M, Grimm, P, Soukup, J, Wetzold, R, Löbel, M, Starke, L, Lellouche, F, Lizotte, P, Declerq, P, Antoine, M, Stephanie, G, Jean-Pierre, E, François, B, Marion, B, Philippe, R, Pourcine, F, Monchi, M, Luis, D, Mercier, R, Sagnier, A, Verrier, N, Caplin, C, Richecoeu, J, Combaux, D, Siami, S, Aparicio, C, Vautier, S, Jeblaoui, A, Lemaire-Brunel, D, D'Aragon, F, Carbonneau, E, Leblond, J, Plantefeve, G, Leparco, C, Contou, D, Fartoukh, M, Courtin, L, Labbe, V, Voiriot, G, Salhi, S, Chassé, M, Carrier, F, Boumahni, D, Benettaib, F, Ghamraoui, A, Sement, A, Gachet, A, Hanisch, A, Haffiane, A, Boivin, A-H, Barreau, A, Guerineau, E, Poupblanc, S, Egreteau, P, Lefevre, M, Bocher, S, Le Loup, G, Le Guen, L, Carn, V, Bertel, M, Antcliffe, D, Templeton, M, Rojo, R, Coghlan, P, Smee, J, Barker, G, Finn, A, Kreb, G, Hoff, U, Hinrichs, C, Nee, J, Mackay, E, Cort, J, Whileman, A, Spencer, T, Spittle, N, Beavis, S, Padmakumar, A, Dale, K, Hawes, J, Moakes, E, Gascoyne, R, Pritchard, K, Stevenson, L, Cooke, J, Nemeth-Roszpopa, K, Gauli, B, Bastola, S, Muller, G, Nay, M-A, Kamel, T, Benzekri, D, Jacquier, S, Runge, I, Mathonnet, A, Barbier, F, Bretagnol, A, Carter, J, Van Der Heyden, K, Mehrtens, J, Morris, A, Morgan, S, Burke, T, Mercier, E, Chartier, D, Salmon, C, Dequin, P-F, Garot, D, Bellemare, D, Cloutier, È, Daher, R, Costerousse, O, Boulanger, M-C, Couillard-Chénard, É, Lauzier, F, Francoeur, C, Francois, B, Gay, A, Anne-Laure, F, Ramali, M, HC, O, Ghosh, A, Osagie, R, Arachchige, M, Hartley, M, Cheung, W, Wong, H, Seigne, P, Eustace, J, O'Callaghan, A-M, O'Brien, F, Bamford, P, Reid, A, Cawley, K, Faulkner, M, Pickering, C, Raj, A, Tsinaslanidis, G, Khade, R, Agha, G, Sekiwala, R, Smith, T, Brewer, C, Gregory, J, Limb, J, Cowton, A, O’Brien, J, Postlethwaite, K, Malakouti, S, Music, E, Ricketts, D, King, A, Clermont, G, Bart, R, Mayr, F, Schoenling, A, Andreae, M, Shetty, V, Brant, E, Malley, B, Donadee, C, Sackrowitz, R, Weissman, A, Yealy, D, Barton, D, Talia, N, Nikitas, N, Wells, C, Lankester, L, McMillan, H, Van den Oever, H, Kruisdijk-Gerritsen, A, Haidar, G, Bain, W, Barbash, I, Fitzpatrick, M, Franz, C, Kitsios, G, Moghbeli, K, Rosborough, B, Shah, F, Suber, T, Pulletz, M, Williams, P, Birch, J, Wiseman, S, Horton, S, Alegria, A, Turki, S, Elsefi, T, Crisp, N, Allen, L, Truman, N, Smith, M, Chukkambotla, S, Goddard, W, Duberley, S, Khan, M, Kazi, A, Simpson, J, Duke, G, Chan, P, Carter, B, Hunter, S, Voigt, I, Schueler, R, Blank, E, Hüning, V, Steffen, M, Goralski, P, Litton, E, Regli, A, Pellicano, S, Palermo, A, Eroglu, E, Bihari, S, Laver, RD, Jin, X, Brown, J, McIntyre, J, French, C, Bates, S, Towns, M, Yang, Y, McGain, F, McCullagh, I, Cairns, T, Hanson, H, Patel, B, Clement, I, Evetts, G, Touma, O, Holland, S, Hodge, C, Taylor, H, Alderman, M, Barnes, N, Da Rocha, J, Smith, C, Brooks, N, Weerasinghe, T, Sinclair, J-A, Abusamra, Y, Doherty, R, Cudlipp, J, Singh, R, Yu, H, Daebis, A, Ng, C, Kendrick, S, Saran, A, Makky, A, Greener, D, Rowe-Leete, L, Edwards, A, Bland, Y, Dolman, R, Foster, T, Laffey, J, McNicholas, B, Scully, M, Casey, S, Kernan, M, Brennan, A, Rangan, R, Tully, R, Corbett, S, McCarthy, A, Duffy, O, Burke, D, Linnett, V, Sanderson, A, Ritzema, J, Wild, H, Lucas, R, Marriott, Y, Andric, Z, Cviljevic, S, Br, R, Zapalac, M, Mirković, G, Khare, D, Pinder, M, Gopinath, A, Kannan, T, Dean, S, Vanmali, P, Depuydt, P, De Waele, J, De Bus, L, Fierens, J, Bracke, S, Vermassen, J, Vermeiren, D, Pugh, R, Lean, R, Qiu, X, Scanlan, J, Evans, A, Davies, G, Lewis, J, Plesnikova, Y, Khoud, A, Coetzee, S, Puxty, K, Cathcart, S, Rimmer, D, Bagot, C, Scott, K, Martin, L, Yusuff, H, Isgro, G, Brightling, C, Bourne, M, Craner, M, Boyles, R, Alexander, B, Roberts, T, Nelli, A, Rosenstein-Sisson, R, Speyer, R, Pech, Y, McCullough, J, Tallott, M, Vazquez-Grande, G, Marten, N, Liu, T, Siddiqui, A, Khanal, S, Amatya, S, Szakmany, T, Cherian, S, Williams, G, James, C, Waters, A, Prout, R, Stedman, R, Davies, L, Pegler, S, Kyeremeh, L, Moorhouse, L, Arbane, G, Marotti, M, Bociek, A, Campos, S, Van Nieuwkoop, K, Ottens, T, Visser, Y, Van den Berg, L, Van der Kraan-Donker, A, Brett, S, Arias, S, Hall, R, Paneru, H, Koirala, S, Paudel, P, Wilson, M, Vaara, S, Pettilä, L, Heinonen, J, Pettilä, V, Jain, S, Gupta, A, Holbrook, C, Antoine, P, Meziani, F, Allam, H, Cattelan, J, Clere-Jehl, R, Helms, J, Kummerlen, C, Merdji, H, Monnier, A, Rahmani, H, Studer, A, Schneider, F, Castelain, V, Morel, G, L’Hotellier, S, Ochin, E, Vanjak, C, Rouge, P, Bendjemar, L, Albert, M, Serri, K, Cavayas, A, Duplaix, M, Williams, V, Catorze, NJTADS, Pereira, TNAL, Ferreira, RMC, Bastos, JMPS, Batista, TMO, Badie, J, Berdaguer, F, Malfroy, S, Mezher, C, Bourgoin, C, Moneger, G, Bouvier, E, Muñoz-Bermúdez, R, Marin-Corral, J, Degracia, A, Gómez, F, López, M, Aceto, R, Aghemo, A, Badalamenti, S, Brunetta, E, Cecconi, M, Ciccarelli, M, Constantini, E, Greco, M, Folci, M, Selmi, C, Voza, A, Henning, J, Bonner, S, Hugill, K, Cirstea, E, Wilkinson, D, Jones, J, Altomy, M, Karlikowski, M, Sutherland, H, Wilhelmsen, E, Woods, J, North, J, Pletz, M, Hagel, S, Ankert, J, Kolanos, S, Bloos, F, Simons, K, Van Zuylen, T, Bouman, A, Kumar, N, Panwar, R, Poulter, A-L, Sunkara, K, Szigligeti, G, Leszkoven, J, Rochwerg, B, Karachi, T, Oczkowski, S, Centofanti, J, Millen, T, Sundaran, D, Hollos, L, Turns, M, Walsh, J, Al Qasim, E, Alswaidan, L, Hegazy, M, Arishi, H, Al Amri, A, AlQahtani, S, Naidu, B, Tlayjeh, H, Hussain, S, Al Enezi, F, Abdukahil, SA, Hopkins, P, Noble, H, O’Reilly, K, Mehta, R, Wong, O, Makanju, E, Rao, D, Sikondari, N, Saha, S, Corcoran, E, Pappa, E, Cockrell, M, Donegan, C, Balaie, M, Nickoleit-Bitzenberger, D, Schaaf, B, Meermeier, W, Prebeg, K, Azzaui, H, Hower, M, Brieger, K-G, Elender, C, Sabelhaus, T, Riepe, A, Akamp, C, Kremling, J, Klein, D, Landsiedel-Mechenbier, E, Laha, S, Verlander, M, Jha, A, Megarbane, B, Voicu, S, Deye, N, Malissin, I, Sutterlin, L, Mrad, A, Lehalleur, A, Naim, G, Nguyen, P, Ekhérian, J-M, Boué, Y, Sidéris, G, Vodovar, D, Guérin, E, Grant, C, Brain, M, Mineall, S, Paramasivam, E, Wilby, E, Ogg, B, Howcroft, C, Aspinwall, A, Charlton, S, Gould, R, Mistry, D, Awan, S, Bedford, C, Carr-Wilkinson, J, Hall, A, Gardiner-Hill, C, Maloney, C, Brunskill, N, Watchorn, O, Hardy, C, Qureshi, H, Flint, N, Nicholson, S, Southin, S, Ghattaoraya, A, Harding, D, O’Halloran, S, Collins, A, Smith, E, Trues, E, Borgatta, B, Turner-Bone, I, Reddy, A, Wilding, L, Wilson, C, Surti, Z, Aneman, A, Miller, J, White, H, Estensen, K, Morrison, L, Sutton, J, Cooper, M, Warnapura, L, Agno, R, Sathianathan, P, Shaw, D, Ijaz, N, Spong, A, Sabaretnam, S, Burns, D, Lang, E, Tate, M, Fischer, R, Biradar, V, Soar, N, Golden, D, Davey, M, Seaman, R, Osborne, A, Bannard-Smith, J, Clark, R, Birchall, K, Henry, J, Pomeroy, F, Quayle, R, Wylie, K, Sukuraman, A, John, M, Sibin, S, Leditschke, A, Finnis, M, Jongebloed, K, Khwaja, K, Campisi, J, Van Vonderen, M, Pietersma, M, Vrolijk, L, Kampschreur, L, Van Gulik, L, Makowski, A, Misztal, B, Haider, S, Liao, A, Squires, R, Oborska, A, Kayani, A, Kalchko-Veyssal, S, Prabakaran, R, Hadebe, B, KalchkoVeyssal, S, Williams, T, Song, R, Morpeth, S, Lai, V, Habraken, H, Stewart, R, Mwaura, E, Mew, L, Wren, L, Willams, F, Sutherland, S-B, Rebello, R, Shehabi, Y, Al-Bassam, W, Hulley, A, Kadam, U, Sathianathan, K, Innes, R, Doble, P, Graham, L, Shovelton, C, Dean, T, Salahuddin, N, Aryal, D, Koirala, K, Rai, N, Luitel, S, Seppelt, I, Whitehead, C, Lowrey, J, Gresham, R, Masters, K, Hamlyn, V, Hawkins, N, Roynon-Reed, A, Cutler, S, Lewis, S, Lazaro, J, Newman, T, Aravindan, L, Asghar, A, Bartholomew, J, Bayne, M, Beddows, S, Birch, C, Brend, M, Byrne, R, Campbell, D, Campbell, H, Chambers, E, Clinton, A, Collins, J, Crawshaw, S, Dawson, LA, Donaldson, K, Drake, C, Dyas, S, Ellis, Y, Gilmour, K, Goodwin, J, Halden, S, Hall, AS, Hanson, J, Harper, H, Harrison, S, Hayes, A, Hodgson, H, Hurford, S-A, Jackson, S, Levett, C, Lock, S, Lockett, T, Logan, M, Lomme, K, Luo, J, Marsh, E, Mguni, N, Monaghan, H, Murphy, S, Muzengi, N, Naz, M, O'Kell, E, Oliver, A, O'Reilly, J, Pearson, K, Porter, D, Potter, A, Rook, C, Rounds, C, Sheffield, J, Shirley, K, Siewersk, C, Skinner, T, Speight, H, Sutu, M, Unsworth, A, Van’t Hoff, W, Walker, S, Williams, H, Williamson, D, Williamson, JD, Duan, E, Tsang, J, Patterson, L, Austin, P, Chapman, S, Cabrelli, L, Fletcher, S, Nortje, J, Fottrell-Gould, D, Randell, G, Stammers, K, Healey, G, Pinto, M, Borrill, Z, Duncan, T, Ustianowski, A, Uriel, A, Eltayeb, A, Alfonso, J, Hey, S, Shaw, J, Fox, C, Lindergard, G, Charles, B, Blackledge, B, Connolly, K, Harris, J, Cuesta, J, Xavier, K, Purohit, D, Elhassan, M, Haldeos, A, Vincent, R, Abdelrazik, M, Jenkins, S, Ganesan, A, Kumar, R, Carter, D, Bakthavatsalam, D, Frater, A, Saleem, M, Everitt, R, Hacking, D, Zaman, M, Elmahi, E, Jones, A, Hall, K, Phillips, M, Terrill, L, Mills, G, Raithatha, A, Bauchmuller, K, Ryalls, K, Harrington, K, Bowler, H, Sall, J, Bourne, R, Gross, J, Massey, N, Adebambo, O, Long, M, Tony, K, Juffermans, N, Koopmans, M, Dujardin, R, Alderink, B, Rowland, M, Hutton, P, Bashyal, A, Davidson, N, Hird, C, Chhablani, M, Phalod, G, Kirkby, A, Archer, S, Netherton, K, Reschreiter, H, Camsooksai, J, Patch, S, Humphrey, C, Flynn, G, Harrington, C, Kruger, P, Walsham, J, Meyer, J, Harward, M, Jones, C, Sathe, S, Roche, L, Davies, E, Skinner, D, Gaylard, J, Newman, J, Pogson, D, Rose, S, Daly, Z, Brimfield, L, Nown, A, Parekh, D, Bergin, C, Bates, M, McGhee, C, Lynch, D, Bhandal, K, Tsakiridou, K, Bamford, A, Cooper, L, Whitehouse, T, Veenith, T, Forster, E, O'Connell, M, Sim, M, Hay, S, Henderson, S, Nygren, M, Valentine, E, Katary, A, Bell, G, Wilcox, L, Mataliotakis, M, Smith, P, Ali, M, Isguzar, A, Phull, M-K, Zaidi, A, Pogreban, T, Rosaroso, L, Harvey, D, Lowe, B, Meredith, M, Ryan, L, Schouten, J, Pickkers, P, Roovers, N, Klop-Riehl, M, Van der Eng, H, Sloots-Cuppen, S, Preijers, L, Van Oosten, N, Moine, P, Heming, N, Maxime, V, Bossard, I, Nicholier, T, Clair, B, Orlikowski, D, Bounab, R, Abdeladim, L, Baker, S, Duroux, M, Ratcliffe, M, Sy, E, Mailman, J, Lee, S, Gupta, C, Kassir, S, López, R, Rodríguez-Gómez, J, Cárcel, S, Carmona, R, De la Fuente, C, Rodriguez, M, Jan Hassing, R, Greven, F, Huijbens, D, Roebers, L, Verheij, H, Miles, H, Attokaran, A, Buehner, U, Williams, E, Chapman, M, O’Connor, S, Glasby, K, Rivett, J, Brown, N, Kutsogiannis, D, Thompson, P, Rooney, K, Rodden, N, Thomson, N, McGlynn, D, Abel, L, Gemmell, L, Sundaram, R, Hornsby, J, Walden, A, Keating, L, Frise, M, Rai, S, Bartley, S, Schuster-Bruce, M, Pitts, S, Miln, R, Purandare, L, Vamplew, L, Dempster, D, Gummadi, M, Dormand, N, Wang, S, Spivey, M, Bean, S, Burt, K, Moore, L, Hammonds, F, Richards, C, Campbell, L, Smyth, K, Day, C, Zitter, L, Benyon, S, Singh, J, Lynch, C, Mikusek, J, Deacon, B, Turner, K, Baker, E, Hickey, J, Champanerkar, S, Aitken, L, LewisProsser, L, Ahmad, N, Wiles, M, Willson, J, Grecu, I, Martin, J, Wrey Brown, C, Arias, A-M, Bevan, E, Westlake, S, Craven, T, Hope, D, Singleton, J, Clark, S, McCulloch, C, Biddie, S, Welters, I, Hamilton, D, Williams, K, Waugh, V, Mulla, S, Waite, A, Roman, J, Martinez, M, Johnston, B, Puthucheary, Z, Martin, T, Santos, F, Uddin, R, Fernandez, M, Seidu, F, Somerville, A, Pakats, M-L, Begum, S, Shahid, T, Presneill, J, Barge, D, Byrne, K, Janin, P, Yarad, E, Bass, F, Hammond, N, Vuylsteke, A, Chan, C, Victor, S, Waterson, S, McNamara, R, Boardman, M, Gattas, D, Buhr, H, Coles, J, Matsa, R, Gellamucho, M, Creagh-Brown, B, Marriot, C, Salberg, A, Zouita, L, Stone, S, Michalak, N, Donlon, S, Mtuwa, S, Mayangao, I, Verula, J, Burda, D, Harris, C, Jones, E, Bradley, P, Tarr, E, Harden, L, Piercy, C, Nolan, J, Kerslake, I, Cook, T, Simpson, T, Dalton, J, Demetriou, C, Mitchard, S, Ramos, L, White, K, Johnson, T, Headdon, W, Spencer, S, White, A, Howie, L, Reay, M, Watts, A, Traverse, E, Jennings, S, Anumakonda, V, Tuckwell, C, Harrow, K, Matthews, J, McGarry, K, Moore, V, Smith, L, Summerfield, A, Dark, P, Harvey, A, Doonan, R, McMorrow, L, Knowles, K, Pendlebury, J, Perez, J, Marsden, T, Taylor, M, Michael, A, Collis, M, Claxton, A, Habeichi, W, Horner, D, Slaughter, M, Thomas, V, Proudfoot, N, Keatley, C, Donnison, P, Casey, R, Irving, B, Matimba-Mupaya, W, Reed, C, Anthony, A, Trim, F, Cambalova, L, Robertson, D, Wilson, A, Hulme, J, Kannan, S, Kinney, F, Senya, H, Ratnam, V, Gill, M, Kirk, J, Shelton, S, Schweikert, S, Wibrow, B, Anstey, M, Rauniyar, R, Khoso, N, Asif, N, Taqdees, H, Frey, C, Scano, R, McKee, M, Murphy, P, Thomas, M, Worner, R, Faulkner, B, Gendall, E, Hayes, K, Blakemore, H, Borislavova, B, Deshpande, K, Van Haren, F, Konecny, P, Inskip, D, Tung, R, Hayes, L, Murphy, L, Neill, A, Reidy, B, O’Dwyer, M, Ryan, D, Ainscough, K, Hamilton-Davies, C, Mfuko, C, Abbass, H, Mandadapu, V, Leaver, S, Patel, K, Farnell-Ward, S, Saluzzio, R, Rawlins, S, Sicat, C, De Keulenaer, B, Ferrier, J, Fysh, E, Davda, A, Mevavala, B, Cook, D, Clarke, F, Banach, D, Fernández de Pinedo Artaraz, Z, Cabreros, L, Latham, V, Kruisselbrink, R, Brochard, L, Burns, K, Sandhu, G, Khalid, I, White, I, Croft, M, Holland, N, Pereira, R, Nair, P, Buscher, H, Reynolds, C, Newman, S, Santamaria, J, Barbazza, L, Homes, J, Smith, R, Zaki, A, Johnson, D, Garrard, H, Juhaz, V, Brown, L, Pemberton, A, Roy, A, Rostron, A, Woods, L, Cornell, S, Fowler, R, Adhikari, N, Kamra, M, Marinoff, N, Garrett, P, Murray, L, Brailsford, J, Fennessy, G, Mulder, J, Morgan, R, Pillai, S, Harford, R, Ivatt, H, Evans, D, Richards, S, Roberts, E, Bowen, J, Ainsworth, J, Kuitunen, A, Karlsson, S, Vahtera, A, Kiiski, H, Ristimäki, S, Albrett, J, Jackson, C, Kirkham, S, Tamme, K, Reinhard, V, Ellervee, A, Põldots, L, Rennit, P, Svitškar, N, Browne, T, Grimwade, K, Goodson, J, Keet, O, Callender, O, Udy, A, McCracken, P, Young, M, Board, J, Martin, E, Kasipandian, V, Patel, A, Allibone, S, Mary-Genetu, R, English, S, Watpool, I, Porteous, R, Miezitis, S, McIntyre, L, Brady, K, Vale, C, Shekar, K, Lavana, J, Parmar, D, Peake, S, Kurenda, C, Hormis, A, Walker, R, Collier, D, Kimpton, S, Oakley, S, Bhagani, S, De Neef, M, Garcia, S, Maharajh, A, Nandani, A, Dobson, J, Fernando, G, Eastgate, C, Gomez, K, Abdi, Z, Tatham, K, Jhanji, S, Black, E, Dela Rosa, A, Howle, R, Baikady, R, Drummond, A, Dearden, J, Philbin, J, Munt, S, Gopal, S, Pooni, J-S, Ganguly, S, Smallwood, A, Metherell, S, Naeem, A, Fagan, L, Ryan, E, Mariappa, V, Foulds, A, Revill, A, Bhattarai, B, De Jonge, E, Wigbers, J, Del Prado, M, Cremer, O, Mulier, J, Peters, A, Romberg, B, Schutgens, R, Troeman, D, Van Opdorp, M, Besten, H, Brakké, K, Barber, R, Hilldrith, A, Kluge, S, Nierhaus, A, Jarczak, D, Roedl, K, Kochanek, M, Rueß-Paterno, G, Mc-Kenzie, J, Eichenauer, D, Shimabukuro-Vornhagen, A, Wilcox, E, Del Sorbo, L, Abdelhady, H, Romagnuolo, T, Simpson, S, Maiden, M, Horton, M, Trickey, J, Krajinovic, V, Kutleša, M, Kotarski, V, Brohi, F, Jagannathan, V, Clark, M, Purvis, S, Wetherill, B, Brajković, A, Babel, J, Sever, H, Dragija, L, Kušan, I, Dushianthan, A, Cusack, R, De Courcy-Golder, K, Salmon, K, Burnish, R, Smith, S, Ruiz, W, Duke, Z, Johns, M, Male, M, Gladas, K, Virdee, S, Swabe, J, Tomlinson, H, Rohde, G, Grünewaldt, A, Bojunga, J, Petros, S, Kunz, K, Schütze, B, Weismann, D, Frey, A, Drayss, M, Goebeler, ME, Flor, T, Fragner, G, Wahl, N, Totzke, J, Sayehli, C, Hakak, S, Altaf, W, O'Sullivan, M, Murphy, A, Walsh, L, Rega La Valle, A, Bewley, J, Sweet, K, Grimmer, L, Johnson, R, Wyatt, R, Morgan, K, Varghese, S, Willis, J, Stratton, E, Kyle, L, Putensen, D, Drury, K, Skorko, A, Bremmer, P, Ward, G, Bassford, C, Sligl, W, Baig, N, Rewa, O, Bagshaw, S, Basile, K, Stavor, D, Burbee, D, McNamara, A, Wunderley, R, Bensen, N, Adams, P, Vita, T, Buhay, M, Scholl, D, Gilliam, M, Winters, J, Doherty, K, Berryman, E, Ghaffari, M, Marroquin, O, Quinn, K, Garrard, W, Kalchthaler, K, Beard, G, Skrtich, A, Bagavathy, K, Drapola, D, Bryan-Morris, K, Arnold, J, Reynolds, B, Hussain, M, Dunsavage, J, Saiyed, S, Hernandez, E, Goldman, J, Brown, C, Comp, S, Raczek, J, Morris, J, Vargas Jr., J, Weiss, D, Hensley, J, Kochert, E, Wnuk, C, Nemeth, C, Mowery, B, Hutchinson, C, Winters, L, McAdams, D, Walker, G, Minnier, T, Wisniewski, M, Mayak, K, McCreary, E, Bariola, R, Viehman, A, Daley, J, Lopus, A, Schmidhofer, M, Ambrosino, R, Keen, S, Toffalo, S, Stambaugh, M, Trimmer, K, Perri, R, Casali, S, Medva, R, Massar, B, Beyerl, A, Burkey, J, Keeler, S, Lowery, M, Oncea, L, Daugherty, J, Sevilla, C, Woelke, A, Dice, J, Weber, L, Roth, J, Ferringer, C, Beer, D, Fesz, J, Carpio, L, Colin, G, Zinzoni, V, Maquigneau, N, Henri-Lagarrigue, M, Pouplet, C, Reill, L, Distler, M, Maselli, A, Martynoga, R, Trask, K, Butler, A, Attwood, B, Parsons, P, Campbell, B, Smith, A, Page, V, Zhao, X, Oza, D, Abrahamson, G, Sheath, B, Young, P, Young, C, Lesona, E, Navarra, L, Cruz, R, Delaney, K, Aguilar-Dano, A, Gojanovic, M, Rhodes, J, Anderson, T, Morris, S, Nayyar, V, Bowen, D, Kong, J, Joy, J, Fuchs, R, Lambert, B, Tai, C, Thomas, A, Keen, A, Tierney, C, Omer, N, Bacon, G, Tridente, A, Shuker, K, Anders, J, Greer, S, Scott, P, Millington, A, Buchanan, P, Binnie, A, Powell, E, McMillan, A, Luk, T, Aref, N, Denmade, C, Sadera, G, Jacob, R, Hughes, D, Sterba, M, Geng, W, Digby, S, Southern, D, Reddy, H, Hulse, S, Campbell, A, Garton, M, Watkins, C, Smuts, S, Quinn, A, Simpson, B, McMillan, C, Finch, C, Hill, C, Cooper, J, Budd, J, Small, C, O’Leary, R, Collins, E, Holland, A, Alexander, P, Felton, T, Ferguson, S, Sellers, K, Ward, L, Yates, D, Birkinshaw, I, Kell, K, Scott, Z, Pearson, H, Hashmi, M, Hassan, N, Panjwani, A, Umrani, Z, Shaikh, M, Ain, Q, Kanwal, D, Van Bree, S, Bouw-Ruiter, M, Osinga, M, Van Zanten, A, McEldrew, R, Rashan, S, Singh, V, Azergui, N, Bari, S, Beltran, M, Brugman, C, Groeneveld, E, Jafarzadeh, M, Keijzer-Timmers, N, Kester, E, Koelink, M, Kwakkenbos-Craanen, M, Okundaye, C, Parker, L, Peters, S, Post, S, Rietveld, I, Scheepstra-Beukers, I, Schreuder, G, Smit, A, Brillinger, N, Markgraf, R, Eichinger, F, Doran, P, Anjum, A, Best-Lane, J, Barton, F, Miller, L, Richards-Belle, A, Saull, M, Sprinckmoller, S, Wiley, D, Darnell, R, Au, C, Lindstrum, K, Cheng, A, Forbes, A, Heritier, S, Trapani, T, Cuthbertson, B, Manoharan, V, Dondrop, A, Tolppa, T, Ehrmann, S, Hullegie, S, Povoa, P, Beasley, R, Daneman, N, McGloughlin, S, Paterson, D, Venkatesh, B, De Jong, M, Uyeki, T, Baillie, K, Netea, M, Orr, K, Patanwala, A, Tong, S, Cooper, N, Galea, J, Leavis, H, Ogungbenro, K, Patawala, A, Rademaker, E, Youngstein, T, Carrier, M, Fergusson, D, Hunt, B, Kumar, A, Laffan, M, Lother, S, Middeldorp, S, Stanworth, S, De Man, A, Masse, M-H, Abraham, J, Arnold, D, Begin, P, Charlewood, R, Chasse, M, Coyne, M, Daly, J, Gosbell, I, Harvala-Simmonds, H, MacLennan, S, McDyer, J, Menon, D, Pridee, N, Roberts, D, Thomas, H, Tinmouth, A, Triulzi, D, Walsh, T, Wood, E, Calfee, C, O’Kane, C, Shyamsundar, M, Sinha, P, Thompson, T, Young, I, Burrell, A, Ferguson, N, Hodgson, C, Orford, N, Phua, J, Baron, R, Epelman, S, Frankfurter, C, Gommans, F, Kim, E, Leaf, D, Vaduganathan, M, Van Kimmenade, R, Sanil, A, Van Beurden, M, Effelaar, E, Schotsman, J, Boyd, C, Harland, C, Shearer, A, Wren, J, Attanayaka, U, Darshana, S, Ishani, P, Udayanga, I, Higgins, AM, Berry, LR, Lorenzi, E, Murthy, S, McQuilten, Z, Mouncey, PR, Al-Beidh, F, Annane, D, Arabi, YM, Beane, A, Van Bentum-Puijk, W, Bhimani, Z, Bonten, MJM, Bradbury, CA, Brunkhorst, FM, Buzgau, A, Buxton, M, Charles, WN, Cove, M, Detry, MA, Estcourt, LJ, Fagbodun, EO, Fitzgerald, M, Girard, TD, Goligher, EC, Goossens, H, Haniffa, R, Hills, T, Horvat, CM, Huang, DT, Ichihara, N, Lamontagne, F, Marshall, JC, McAuley, DF, McGlothlin, A, McGuinness, SP, McVerry, BJ, Neal, MD, Nichol, AD, Parke, RL, Parker, JC, Parry-Billings, K, Peters, SEC, Reyes, LF, Rowan, KM, Saito, H, Santos, MS, Saunders, CT, Serpa-Neto, A, Seymour, CW, Shankar-Hari, M, Stronach, LM, Turgeon, AF, Turner, AM, Van de Veerdonk, FL, Zarychanski, R, Green, C, Lewis, RJ, Angus, DC, McArthur, CJ, Berry, S, Derde, LPG, Gordon, AC, Webb, SA, Lawler, PR, Comm REMAP-CAP Investigators, Apollo - University of Cambridge Repository, Intensive Care Medicine, Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Hôpital Raymond Poincaré [Garches], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Pittsburgh Foundation, PF, Amgen, Health Research Board, HRB: CTN 2014-012, Horizon 2020 Framework Programme, H2020: 101003589, Translational Breast Cancer Research Consortium, TBCRC, Canadian Institutes of Health Research, IRSC: 158584, Heart and Stroke Foundation of Canada, HSF, National Institute for Health and Care Research, NIHR, European Commission, EC, National Health and Medical Research Council, NHMRC: 1101719, APP194811, CS-2016-16-011, GNT2008447, RP-2015-06-18, Office of Health and Medical Research, OHMR, Health Research Council of New Zealand, HRC: 16/631, Eisai, Ministère des Affaires Sociales et de la Santé: PHRC-20-0147, Université Pierre et Marie Curie, UPMC, NIHR Imperial Biomedical Research Centre, BRC, Minderoo Foundation, Funding/Support : The Platform for European Preparedness Against (Re-) emerging Epidemics (PREPARE) consortium by the European Union, FP7-HEALTH-2013-INNOVATION-1 (#602525), the Rapid European COVID-19 Emergency Research response (RECOVER) consortium by the European Union’s Horizon 2020 research and innovation programme (#101003589), the Australian National Health and Medical Research Council (#APP1101719), the Australian Medical Research Future Fund (#APP2002132), the Health Research Council of New Zealand (#16/631), the Canadian Institutes of Health Research Strategy for Patient-Oriented Research Innovative Clinical Trials Program Grant (#158584) and the Canadian Institute of Health Research COVID-19 Rapid Research Funding (#447335), the UK National Institute for Health Research (NIHR) and the NIHR Imperial Biomedical Research Centre, the Health Research Board of Ireland (CTN 2014-012), the UPMC Learning While Doing Program, the Translational Breast Cancer Research Consortium, the French Ministry of Health (PHRC-20-0147), the Wellcome Trust Innovations Project (215522), the Minderoo Foundation, the EU Programme Emergency Support Instrument, the NHS Blood and Transplant Research and Development Programme, the Translational Breast Cancer Research Consortium, the NSW Office of Health and Medical Research, Amgen, Eisai, and the Pittsburgh Foundation. Dr Higgins is funded by an NHMRC Emerging Leadership Fellowship (GNT2008447). Dr McQuilten is funded by an NHMRC Emerging Leadership Fellowship (APP194811). Dr Gordon is funded by an NIHR Research Professorship (RP-2015-06-18) and Dr Shankar-Hari by an NIHR Clinician Scientist Fellowship (CS-2016-16-011). Dr Turgeon is the Chairholder of the Canada Research Chair in Critical Care Neurology and Trauma. Dr Lawler is supported by a career award from the Heart and Stroke Foundation of Canada., and European Project: 602525,EC:FP7:HEALTH,FP7-HEALTH-2013-INNOVATION-1,PREPARE(2014)
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Adult ,Male ,corticosteroid ,[SDV]Life Sciences [q-bio] ,Critical Illness ,lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4] ,antiplatelet ,Lopinavir ,Adaptive platform trial randomized controlled trial intensive care, pneumonia COVID-19 antiplatelet immunoglobulin antiviral corticosteroid immune modulation anticoagulation ,All institutes and research themes of the Radboud University Medical Center ,Adrenal Cortex Hormones ,Humans ,anticoagulation ,intensive care, pneumonia ,COVID-19 Serotherapy ,Original Investigation ,Medicine(all) ,immune modulation ,Ritonavir ,SARS-CoV-2 ,COVID-19 ,Anticoagulants ,Bayes Theorem ,General Medicine ,Middle Aged ,antiviral ,Receptors, Interleukin-6 ,Adaptive platform trial ,randomized controlled trial ,Female ,Human medicine ,immunoglobulin ,Follow-Up Studies ,Hydroxychloroquine - Abstract
ImportanceThe longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown.ObjectiveTo determine the effect of multiple interventions for critically ill adults with COVID-19 on longer-term outcomes.Design, Setting, and ParticipantsPrespecified secondary analysis of an ongoing adaptive platform trial (REMAP-CAP) testing interventions within multiple therapeutic domains in which 4869 critically ill adult patients with COVID-19 were enrolled between March 9, 2020, and June 22, 2021, from 197 sites in 14 countries. The final 180-day follow-up was completed on March 2, 2022.InterventionsPatients were randomized to receive 1 or more interventions within 6 treatment domains: immune modulators (n = 2274), convalescent plasma (n = 2011), antiplatelet therapy (n = 1557), anticoagulation (n = 1033), antivirals (n = 726), and corticosteroids (n = 401).Main Outcomes and MeasuresThe main outcome was survival through day 180, analyzed using a bayesian piecewise exponential model. A hazard ratio (HR) less than 1 represented improved survival (superiority), while an HR greater than 1 represented worsened survival (harm); futility was represented by a relative improvement less than 20% in outcome, shown by an HR greater than 0.83.ResultsAmong 4869 randomized patients (mean age, 59.3 years; 1537 [32.1%] women), 4107 (84.3%) had known vital status and 2590 (63.1%) were alive at day 180. IL-6 receptor antagonists had a greater than 99.9% probability of improving 6-month survival (adjusted HR, 0.74 [95% credible interval {CrI}, 0.61-0.90]) and antiplatelet agents had a 95% probability of improving 6-month survival (adjusted HR, 0.85 [95% CrI, 0.71-1.03]) compared with the control, while the probability of trial-defined statistical futility (HR >0.83) was high for therapeutic anticoagulation (99.9%; HR, 1.13 [95% CrI, 0.93-1.42]), convalescent plasma (99.2%; HR, 0.99 [95% CrI, 0.86-1.14]), and lopinavir-ritonavir (96.6%; HR, 1.06 [95% CrI, 0.82-1.38]) and the probabilities of harm from hydroxychloroquine (96.9%; HR, 1.51 [95% CrI, 0.98-2.29]) and the combination of lopinavir-ritonavir and hydroxychloroquine (96.8%; HR, 1.61 [95% CrI, 0.97-2.67]) were high. The corticosteroid domain was stopped early prior to reaching a predefined statistical trigger; there was a 57.1% to 61.6% probability of improving 6-month survival across varying hydrocortisone dosing strategies.Conclusions and RelevanceAmong critically ill patients with COVID-19 randomized to receive 1 or more therapeutic interventions, treatment with an IL-6 receptor antagonist had a greater than 99.9% probability of improved 180-day mortality compared with patients randomized to the control, and treatment with an antiplatelet had a 95.0% probability of improved 180-day mortality compared with patients randomized to the control. Overall, when considered with previously reported short-term results, the findings indicate that initial in-hospital treatment effects were consistent for most therapies through 6 months.
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- 2023
8. Origins of nanoscale emission inhomogeneities of high content red emitting InGaN/InGaN quantum wells.
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Samuel, B., Cooper, D., Rochat, N., Mavel, A., Barbier, F., and Dussaigne, A.
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PHOSPHORS ,QUANTUM wells ,SCANNING transmission electron microscopy ,FOCUSED ion beams ,QUANTUM efficiency - Abstract
The origin of the nanoscale emission inhomogeneities of red emitting InGaN/InGaN quantum wells (QWs) grown directly on a GaN template and on an InGaN on sapphire (InGaNOS) substrate is investigated. InGaNOS is a partly relaxed InGaN pseudo-substrate fabricated by Soitec. As the latter approach provides an interesting optical internal quantum efficiency of 6.5% at 624 nm at 290 K, a deeper study, at the microstructure level, was conducted. The emission inhomogeneities on InGaNOS were highlighted by cathodoluminescence wavelength mappings where three areas were chosen: one emitting at a shorter wavelength, i.e., 588 nm, and two at a longer wavelength, i.e., 607 and 611 nm. Specimens from these zones were extracted by focused ion beam milling to perform cross-sectional characterization techniques. High-angle annular dark field scanning transmission electron microscopy images demonstrated that, while red emitting areas present homogeneous QWs, shorter wavelength areas exhibit non-uniform QWs, in terms of thickness and In composition. Complementary deformation mappings in the growth direction obtained by geometrical phase analysis show that longer emission wavelengths are originating from homogeneous QWs with an InN mole fraction evaluated at 39.0 ± 1.5%. This result demonstrates the possibility of achieving red emission with a coherent (In,Ga)N alloy when using an adapted substrate. A comparison of identical QWs grown on a GaN template is also given. [ABSTRACT FROM AUTHOR]
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- 2021
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9. Staphylocoques à coagulase négative : quand, comment et pourquoi sont-ils responsables d’infections ?
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Barbier, F.
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- 2015
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10. Tuberculose chez les patients de réanimation
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Nay, M.-A. and Barbier, F.
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- 2017
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11. Initiation of forward gait with lateral occurrence of emotional stimuli: general findings and relevance for pedestrians crossing roads
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Caffier, D., Gillet, C., Heurley, L. P., Bourrelly, A., Barbier, F., and Naveteur, J.
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- 2017
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12. Full InGaN red light emitting diodes.
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Dussaigne, A., Barbier, F., Damilano, B., Chenot, S., Grenier, A., Papon, A. M., Samuel, B., Ben Bakir, B., Vaufrey, D., Pillet, J. C., Gasse, A., Ledoux, O., Rozhavskaya, M., and Sotta, D.
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LIGHT emitting diodes , *INDIUM gallium nitride , *NITROGEN , *QUANTUM efficiency , *QUANTUM wells , *BUFFER layers , *DELAYED fluorescence - Abstract
The full InGaN structure is used to achieve red light emitting diodes (LEDs). This LED structure is composed of a partly relaxed InGaN pseudo-substrate fabricated by Soitec, namely, InGaNOS, a n-doped buffer layer formed by a set of InxGa1−xN/GaN superlattices, thin InyGa1−yN/InxGa1−xN multiple quantum wells, and a p doped InxGa1−xN area. p-doped InGaN layers are first studied to determine the optimal Mg concentration. In the case of an In content of 2%, an acceptor concentration of 1 × 1019/cm3 was measured for a Mg concentration of 2 × 1019/cm3. Red electroluminescence was then demonstrated for two generations of LEDs, including chip sizes of 300 × 300 μm2 and 50 × 50 μm2. The differences between these two LED generations are detailed. For both devices, red emission with a peak wavelength at 620 nm was observed for a pumping current density of 12 A/cm2. Red light-emission is maintained over the entire tested current range. From the first to the second LED generation, the maximum external quantum efficiency, obtained in the range of 17–40 A/cm2, was increased by almost one order of magnitude (a factor of 9), thanks to the different optimizations. [ABSTRACT FROM AUTHOR]
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- 2020
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13. Correction to: Functional outcomes in adult patients with herpes simplex encephalitis admitted to the ICU: a multicenter cohort study
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Jaquet, P., de Montmollin, E., Dupuis, C., Sazio, C., Conrad, M., Susset, V., Demeret, S., Tadie, J. M., Argaud, L., Barbier, F., Sarton, B., Chabane, R., Daubin, D., Brulé, N., Lerolle, N., Alves, M., Da Silva, D., Kalioubi, A. El, Silva, S., Bailly, P., Wolff, M., Bouadma, L., Timsit, J. F., Sonneville, R., and ENCEPHALITICA study group
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- 2019
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14. Steering wheel hand position in low-speed maneuvers
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Schiro, J., Gabrielli, F., Pudlo, P., Djemai, M., and Barbier, F.
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- 2013
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15. Nouvelles recommandations pour les infections associées au biofilm : implications en réanimation
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Lebeaux, D., Lucet, J. -C., and Barbier, F. S.
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- 2016
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16. Défaillance rénale chez le patient infecté par le VIH
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Bretagnol, A. and Barbier, F.
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- 2015
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17. Enhanced precision of ankle torque measure with an open-unit dynamometer mounted with a 3D force-torque sensor
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Toumi, A., Leteneur, S., Gillet, C., Debril, J.-F., Decoufour, N., Barbier, F., Jakobi, J. M., and Simoneau-Buessinger, Emilie
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- 2015
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18. Determination of toxic elements (mercury, cadmium, lead, tin and arsenic) in fish and shellfish samples. Risk assessment for the consumers
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Olmedo, P., Pla, A., Hernández, A.F., Barbier, F., Ayouni, L., and Gil, F.
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- 2013
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19. Industrial Process Leading to 19.8% on N-Type Cz Silicon
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Cabal, Veschetti, Y., Sanzone, V., Manuel, S., Gall, S., Barbier, F., Ozanne, F., Bettinelli, Gillot, C., Novel, B., and Ribeyron, P.J.
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- 2013
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20. Improving the UML Metamodel to Rigorously Specify Aggregation and Composition
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Bruel, J.-M., Henderson-Sellers, B., Barbier, F., Le Parc, A., France, E. B., Wang, Xingxu, editor, Johnston, Ronald, editor, and Patel, Shushma, editor
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- 2001
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21. Cessation of screening for intestinal carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae in a low-endemicity intensive care unit with universal contact precautions
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Jalalzaï, W., Boutrot, M., Guinard, J., Guigon, A., Bret, L., Poisson, D.-M., Boulain, T., and Barbier, F.
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- 2018
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22. Radiochemical methodologies applied to determination of zirconium isotopes in low-level waste samples from nuclear power plants
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Oliveira, T. C., Monteiro, R. P. G., Kastner, G. F., Bessueille-Barbier, F., and Oliveira, A. H.
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- 2014
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23. An Institution-Independent Proof of the Beth Definability Theorem
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Aiguier, M. and Barbier, F.
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- 2007
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24. Secular trends and dynamics of hospital associated methicillin-resistant Staphylococcus aureus
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Armand-Lefevre, L., Buke, C., Ruppe, E., Barbier, F., Lolom, I., Andremont, A., Ruimy, R., and Lucet, J.-C.
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- 2010
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25. Philosophie ou Commerce? L’évolution des systèmes de classement bibliographique dans les catalogues de bibliothèques privées publiés en France au XVIIIe siècle
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Blom, H.M.C.W., Barbier, F., Monok, I., Barbier, F., and Monok, I.
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Europe in a Changing World ,Transnational Europe - Abstract
Contains fulltext : 228963pub.pdf (Publisher’s version ) (Closed access) Les bibliothèques et l’économie des connaissances/Bibliotheken und die Ökonomie des Wissens 1450–1850, 09 april 2019
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- 2020
26. Insuffisance respiratoire aiguë chez le patient infecté par le virus de l’immunodéficience humaine
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Barbier, F., Coquet, I., and Azoulay, É.
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- 2010
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27. Isometric Strengh Database for Muscle Maximal Voluntary Endurance Field Tests:Normative Data
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Janik, F. (Frederick), Toulotte, C. (Claire), Seichepine, A-L. (Anne-Laure), Masquelier, B. (Bernadette), Barbier, F. (Fabienne), Fabre, C. (Claudine), Université de Lille, Univ. Artois, Univ. Littoral Côte d’Opale, Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS], and Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369
- Abstract
Background: Different field tests are used to evaluate muscle capacity, in particular maximal voluntary isometric endurance. However, although there are some normative values for a few muscle endurance tests, these do not consider the weight, height, gender, or age of individuals, which are well-known factors that influence muscle performance. Hypothesis/Purpose: The purpose of this study was to investigate the test–retest reproducibility of eight field tests and establish muscle endurance norms, in a healthy population, based on their anthropometric characteristics, which could allow the optimal evaluation of the entire muscle function in a quick manner. Design: Case series. Methods: This study was conducted in two phases. The first phase was to check the reproducibility inter- and intra-assessor for eight isometric muscle field tests on 20 volunteer subjects aged 40.9 ± 11.6 years old (age range, 21–58 years). The second part was to establish muscle maximal voluntary isometric endurance norms according to these tests on a total of 400 healthy participants grouped by age (50 males and females in each of the age brackets, 20–29; 30–39; 40–49; 50–59 years old, for a total of 200 males and 200 females). Results: The intra- and inter-assessor reproducibility tests are good for all muscle measurements (the intraclass correlation coefficients varied between 0.915 and 0.996 and the coefficient of variation between 3.6 and 11.8%). The area under the receiver operating characteristic curves demonstrates a good sensibility with values greater than 0.7 for each test. Each muscle belt presents same ratio regardless of the age and gender group. The simultaneous multiple regression analyses highlight that the anthropometric characteristics of subjects influence significantly the performance of isometric tests. Conclusion: This study has permitted establishing prediction equations in a healthy population according to their anthropometric characteristics as well as agonist/antagonist ratios for eight muscle isometric field tests after demonstrating a good reproducibility of all tests. 7;47
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- 2021
28. Performance of the ROX index to predict intubation in immunocompromised patients receiving high-flow nasal cannula for acute respiratory failure
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Lemiale, V, Dumas, G, Demoule, A, Pène, F, Kouatchet, A, Bisbal, M, Nseir, S, Argaud, L, Kontar, L, Klouche, K, Barbier, F, Seguin, A, Louis, G, Constantin, JM, Mayaux, J, Wallet, F, Peigne, V, Girault, C, Oziel, J, Nyunga, M, Terzi, N, Bouadma, L, Lautrette, A, Bige, N, Raphalen, JH, Papazian, L, Bruneel, F, Lebert, C, Benoit, Dominique, Meert, AP, Jaber, S, Mokart, D, Darmon, M, Azoulay, E, de Recherche en Reanimation Respiratoire du patient d’Onco-Hématologie (GRRR-OH, Groupe, Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC), Mécanismes physiologiques et conséquences des calcifications cardiovasculaires: rôle des remodelages cardiovasculaires et osseux, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Picardie Jules Verne (UPJV), Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), and Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)
- Subjects
medicine.medical_specialty ,Multivariate analysis ,Oxygenation index ,high-flow nasal oxygen ,medicine.medical_treatment ,Acute respiratory failure ,Critical Care and Intensive Care Medicine ,medicine.disease_cause ,[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,Anesthesiology ,Medicine and Health Sciences ,medicine ,[SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO] ,Intubation ,Immunocompromised ,acute respiratory failure ,business.industry ,Research ,lcsh:Medical emergencies. Critical care. Intensive care. First aid ,Correction ,030208 emergency & critical care medicine ,lcsh:RC86-88.9 ,High-flow nasal oxygen ,medicine.disease ,3. Good health ,Pneumonia ,immunocompromised ,030228 respiratory system ,Anesthesia ,Economie ,business ,Nasal cannula - Abstract
Background: Delayed intubation is associated with high mortality. There is a lack of objective criteria to decide the time of intubation. We assessed a recently described combined oxygenation index (ROX index) to predict intubation in immunocompromised patients. The study is a secondary analysis of randomized trials in immunocompromised patients, including all patients who received high-flow nasal cannula (HFNC). The first objective was to evaluate the accuracy of the ROX index to predict intubation for patients with acute respiratory failure. Results: In the study, 302 patients received HFNC. Acute respiratory failure was mostly related to pneumonia (n = 150, 49.7%). Within 2 (1–3) days, 115 (38.1%) patients were intubated. The ICU mortality rate was 27.4% (n = 83). At 6 h, the ROX index was lower for patients who needed intubation compared with those who did not [4.79 (3.69–7.01) vs. 6.10 (4.48–8.68), p < 0.001]. The accuracy of the ROX index to predict intubation was poor [AUC = 0.623 (0.557–0.689)], with low performance using the threshold previously found (4.88). In multivariate analysis, a higher ROX index was still independently associated with a lower intubation rate (OR = 0.89 [0.82–0.96], p = 0.04). Conclusion: A ROX index greater than 4.88 appears to have a poor ability to predict intubation in immunocompromised patients with acute respiratory failure, although it remains highly associated with the risk of intubation and may be useful to stratify such risk in future studies., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2021
29. Repolarization in Patients with Ischemic and Non-Ischemic Cardiomyopathy
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Niederseer, David, Rossi, Valentina A, Barbier, F, Schmied, Christian M, Bohm, Philipp, et al, and University of Zurich
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10209 Clinic for Cardiology ,610 Medicine & health - Published
- 2020
30. New separation method for organic and inorganic selenium compounds based on anion exchange chromatography followed by inductively coupled plasma mass spectrometry
- Author
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Ayouni, L., Barbier, F., Imbert, J. L., Gauvrit, J. Y., Lantéri, P., and Grenier-Loustalot, M. F.
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- 2006
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31. Determinants And Prognostic Value of Sepsis-Associated Encephalopathy: Insights From The Prospective Multicentre Outcomerea Registry
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Poujade, J, Sonneville, R, Garrouste-Orgeas, M, Souweine, B, Azoulay, E, Darmon, M, Mariotte, E, Argaud, L, Barbier, F, Goldgran-Toledano, D, Marcotte, G, Anne-Sophie, D, Jamali, S, Laurent, V, Ruckly, S, Timsit, JF, and OUTCOMEREA
- Published
- 2015
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32. Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae in Critically Ill Patients: Impact of Carriage And Infection On Carbapenem Consumption, Duration of Icu Stay, And Mortality
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Barbier, F, Pommier, C, Garrouste-Orgeas, M, Schwebel, C, Ruckly, S, Dumenil, AS, Lemiale, V, Mourvillier, B, Clec'h, C, Darmon, M, Laurent, V, Marcotte, G, Souweine, B, Zahar, JR, Timsit, JF, and for the OUTCOMEREA Study Group
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- 2015
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33. Bioaccumulation of chromium in aquatic macrophyte Borreria scabiosoides Cham. & Schltdl.
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Mangabeira, P.A., Mielke, M.S., Arantes, I., Dutruch, L., Silva, D.da.C., Barbier, F., de Almeida, A.-A.F., Oliveira, A.H., Severo, M.I.G., Labejof, L., Rocha, D.C., Rosa, T.S., Santana, K.B., Gavrilov, K.L., Galle, P., Levi-Setti, R., and Grenier-Loustalot, M.F.
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- 2006
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34. Corrosion of martensitic and austenitic steels in liquid gallium
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Barbier, F. and Blanc, J.
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- 1999
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35. Determination of the internal piezoelectric potentials and indium concentration in InGaN based quantum wells grown on relaxed InGaN pseudo-substrates by off-axis electron holography
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Cooper, D, primary, Boureau, V, additional, Even, A, additional, Barbier, F, additional, and Dussaigne, A, additional
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- 2020
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36. Benzene exposure in car mechanics and road tanker drivers
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Javelaud, B., Vian, L., Molle, R., Allain, P., Allemand, B., André, B., Barbier, F., Churet, A. M., Dupuis, J., Galand, M., Millet, F., Talmon, J., Touron, C., Vaissière, M., Vechambre, D., Vieules, M., and Viver, D.
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- 1998
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37. Simplification and First Validation of a Short Battery of Patient Questionnaires for Clinical Management of HIV-Infected Patients: The HIV-SQUAD (Symptom Quality of life Adherence) Questionnaire®
- Author
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Spire, B., Arnould, B., Barbier, F., Durant, J., Gilquin, J., Landman, R., Carret, S., Saussier, C., El Kebir, S., and Cohen-Codar, I.
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- 2009
38. Effect of trunk inclination on lower limb joint and lumbar moments in able men during the stance phase of gait
- Author
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Leteneur, S., Gillet, C., Sadeghi, H., Allard, P., and Barbier, F.
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- 2009
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39. Le coasting et les protocoles de stimulation chez les hyperrépondeuses en AMP
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Merviel, P., Claeys, C., Héraud, M.-H., Lourdel, E., Lanta, S., Barbier, F., and Nasreddine, A.
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- 2005
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40. A use case driven requirements engineering process
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Dano, B., Briand, H., and Barbier, F.
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- 1997
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41. Diagnosis and outcome of acute respiratory failure in immunocompromised patients after bronchoscopy
- Author
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Bauer, Pr, Chevret, S, Yadav, H, Mehta, S, Pickkers, P, Bukan, Rb, Rello, J, van de Louw, A, Klouche, K, Meert, Ap, Martin-Loeches, I, Marsh, B, Crespi, Ls, Moreno-Gonzalez, G, Buchtele, N, Amrein, K, Balik, M, Antonelli, Massimo, Nyunga, M, Barratt-Due, A, Bergmans, Dcjj, Spoelstra-de Man, Ame, Kuitunen, A, Wallet, F, Seguin, A, Metaxa, V, Lemiale, V, Burghi, G, Demoule, A, Karvunidis, T, Cotoia, A, Klepstad, P, Moller, Am, Mokart, D, Azoulay, E, Rabbat, A, Darmon, M, Platon, L, Mayaux, J, Chermak, A, Lemaitre, C, Artaud-Macari, E, Nelsen, J, Kaufmann, T, Viana, W, Lishoa, T, Correa, Td, Encina, B, Socias, A, Manez, R, Rodriguez-Ruis, E, Benoit, D, Staudinger, T, Heinz, G, Sengolge, G, Zauner, C, Jaksch, P, Mcmahon, A, Martin, B, Cinnella, G, Shah, S, Hemelaar, P, Taccone, Fs, Salluh, J, Schellongowski, P, Rusinova, K, Terzi, N, Kouatchet, A, Valkonen, M, Bruneel, F, Pene, F, Moreau, As, Girault, C, Silva, Uva, Montini, Luca, Barbier, F, Gaborit, B, Viana, Wn, de Moraes, App, Moralez, Gm, Vinatier, I, Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Institut National de la Recherche Agronomique (INRA)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de biostatistiques et information médicale [Saint-Louis], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Cité (UPC), University of Toronto, Radboud University Medical Center [Nijmegen], Centro de Investigación Biomédica en Red Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III [Madrid] (ISC), Vall d'Hebron University Hospital [Barcelona], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut Jules Bordet [Bruxelles], Faculté de Médecine [Bruxelles] (ULB), Université libre de Bruxelles (ULB)-Université libre de Bruxelles (ULB), Université libre de Bruxelles (ULB), St James's University Hospital, Leeds Teaching Hospitals NHS Trust, Universitat de Barcelona (UB), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Service de réanimation médicale [CHU Caen], Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Sorbonne Université (SU), Service de Pneumologie et Réanimation Médicale [CHU Pitié-Salpêtrière] (Département ' R3S '), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Neurophysiologie Respiratoire Expérimentale et Clinique (UMRS 1158), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Recherche Agronomique (INRA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université de Paris (UP), Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Neurophysiologie Respiratoire Expérimentale et Clinique, Intensive Care, MUMC+: MA Medische Staf IC (9), MUMC+: MA Arts Assistenten IC (9), RS: NUTRIM - R2 - Liver and digestive health, Intensive care medicine, ACS - Atherosclerosis & ischemic syndromes, and ACS - Diabetes & metabolism
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,[SDV]Life Sciences [q-bio] ,lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4] ,BRONCHOALVEOLAR LAVAGE ,HEMATOLOGIC MALIGNANCIES ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,All institutes and research themes of the Radboud University Medical Center ,Bronchoscopy ,law ,Settore MED/41 - ANESTESIOLOGIA ,Severity of illness ,FLEXIBLE BRONCHOSCOPY ,medicine ,030212 general & internal medicine ,Prospective cohort study ,UTILITY ,medicine.diagnostic_test ,business.industry ,GROUPE ,Diagnosis outcome acute respiratory failure immunocompromised patients ,Intensive care unit ,3. Good health ,ONCOLOGY PATIENTS ,Bronchoalveolar lavage ,YIELD ,030228 respiratory system ,Respiratory failure ,INFECTIONS ,SAFETY ,Propensity score matching ,Emergency medicine ,Observational study ,Pneumologie ,business - Abstract
OBJECTIVE: We wished to explore the use, diagnostic capability and outcomes of bronchoscopy added to noninvasive testing in immunocompromised patients. In this setting, an inability to identify the cause of acute hypoxaemic respiratory failure is associated with worse outcome. Every effort should be made to obtain a diagnosis, either with noninvasive testing alone or combined with bronchoscopy. However, our understanding of the risks and benefits of bronchoscopy remains uncertain. PATIENTS AND METHODS: This was a pre-planned secondary analysis of Efraim, a prospective, multinational, observational study of 1611 immunocompromised patients with acute respiratory failure admitted to the intensive care unit (ICU). We compared patients with noninvasive testing only to those who had also received bronchoscopy by bivariate analysis and after propensity score matching. RESULTS: Bronchoscopy was performed in 618 (39%) patients who were more likely to have haematological malignancy and a higher severity of illness score. Bronchoscopy alone achieved a diagnosis in 165 patients (27% adjusted diagnostic yield). Bronchoscopy resulted in a management change in 236 patients (38% therapeutic yield). Bronchoscopy was associated with worsening of respiratory status in 69 (11%) patients. Bronchoscopy was associated with higher ICU (40% versus 28%; p, SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2019
42. B. Fratzke-Weiss, Europäische und nationale Konzeptionen im Rheinbund. Politische Zeitschriften als Medien der politischen Öffentlichkeit, 1997
- Author
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Barbier, F.
- Abstract
Francia, Bd. 26 Nr. 2 (1999)
- Published
- 2019
- Full Text
- View/download PDF
43. U. Neddermeyer, Von der Handschrift zum gedruckten Buch. Schriftlichkeit und Leseinteresse im Mittelalter und in der frühen Neuzeit. Quantitative und qualitative Aspekte. 1: Text. 2: Anlagen, 1998
- Author
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Barbier, F.
- Abstract
Francia, Bd. 27 Nr. 2 (2000)
- Published
- 2019
- Full Text
- View/download PDF
44. A. Wild, Von Gutenberg zu Diderot. Die Handwerke des Buches im Kupferstich der Aufklärung, 2000
- Author
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Barbier, F.
- Abstract
Francia, Bd. 32 Nr. 2 (2005)
- Published
- 2019
- Full Text
- View/download PDF
45. L. G. Svensson, Die Geschichte der Bibliotheca Bipontina. Mit einem Katalog der Handschriften, 2002
- Author
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Barbier, F.
- Abstract
Francia, Bd. 32 Nr. 2 (2005)
- Published
- 2019
- Full Text
- View/download PDF
46. Books and the sciences in history, ed. by M. Frasca-Spade, N. Jardine, 2000
- Author
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Barbier, F.
- Abstract
Francia, Bd. 32 Nr. 2 (2005)
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- 2019
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- View/download PDF
47. Rationalizing antimicrobial therapy in the ICU: a narrative review
- Author
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Timsit, J.-F. Bassetti, M. Cremer, O. Daikos, G. de Waele, J. Kallil, A. Kipnis, E. Kollef, M. Laupland, K. Paiva, J.-A. Rodríguez-Baño, J. Ruppé, É. Salluh, J. Taccone, F.S. Weiss, E. Barbier, F.
- Abstract
The massive consumption of antibiotics in the ICU is responsible for substantial ecological side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this environment. Strikingly, up to half of ICU patients receiving empirical antibiotic therapy have no definitively confirmed infection, while de-escalation and shortened treatment duration are insufficiently considered in those with documented sepsis, highlighting the potential benefit of implementing antibiotic stewardship programs (ASP) and other quality improvement initiatives. The objective of this narrative review is to summarize the available evidence, emerging options, and unsolved controversies for the optimization of antibiotic therapy in the ICU. Published data notably support the need for better identification of patients at risk of MDRB infection, more accurate diagnostic tools enabling a rule-in/rule-out approach for bacterial sepsis, an individualized reasoning for the selection of single-drug or combination empirical regimen, the use of adequate dosing and administration schemes to ensure the attainment of pharmacokinetics/pharmacodynamics targets, concomitant source control when appropriate, and a systematic reappraisal of initial therapy in an attempt to minimize collateral damage on commensal ecosystems through de-escalation and treatment-shortening whenever conceivable. This narrative review also aims at compiling arguments for the elaboration of actionable ASP in the ICU, including improved patient outcomes and a reduction in antibiotic-related selection pressure that may help to control the dissemination of MDRB in this healthcare setting. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature.
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- 2019
48. Influence of isosorbide dinitrate on superior mesenteric artery impedance in humans
- Author
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Voet, D., Afschrift, M., Duprez, D., De Buyzere, M., and Barbier, F.
- Published
- 1993
- Full Text
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49. Evaluation de l'impact des opérations de gestion sédimentaire du Rhône sur la qualité des eaux du fleuve par échantillonnage passif
- Author
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Bretier, M., Dabrin, Aymeric, Panay, J., Le Bescond, C., Grisot, G., Dherret, L., Gahou, J., Bessueille Barbier, F., Coquery, Marina, IRSTEA LYON UR RIVERLY FRA, UNIVERSITE DE LYON UMR 5280 INSTITUT DES SCIENCES ANALYTIQUES VILLEURBANNE FRA, RiverLy (UR Riverly), Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA), and Université de Lyon
- Subjects
OPÉRATIONS DE GESTION SÉDIMENTAIRE ,ECHANTILLONNEUR PASSIF ,FRACTION DISSOUTE ,diffusive gradient in thin films ,ZABR - OBSERVATOIRE OSR ,Rhône ,Contaminants inorganiques ,DGT ,sediment ,[SDE]Environmental Sciences ,Opérations de gestion sédimentaire ,CONTAMINANTS INORGANIQUES ,RHÔNE ,Fraction dissoute ,GRADIENT DE DIFFUSION EN COUCHE MINCE - Abstract
International audience; To prevent flood risks due to bed elevation, dam flushing operations are regularly conducted on the upstream part of the Rhône River to flush away sediments accumulated over time upstream the dams. The extreme increase of suspended particulate matter concentrations (up to 15 g/L) suggests a potential release of contaminants. In the aim of evaluating spatial and temporal variability of dissolved metals concentrations during this event, a sampling strategy combining grab and passive sampling by DGT was set on 3 different sites. During the event, the temporal monitoring of dissolved metals showed that Cd, Cu, Fe, Hg, Pb, and Zn concentrations were not altered, whereas those of As, Co, Mn, Mo, Ni, Sb and U were multiplied by 2 to 22. These dissolved contaminants originated in part from remobilized particles, as the increases could not be explained by the sole contribution of interstitial water from sediment. Moreover, DGT measurements confirmed the low and stable concentrations for Cu, Fe, Pb and Zn and demonstrated a mean concentration for As, Co, Mn and Ni which reflects the concentration increase during the event. Finally, speciation analyses showed that before the event, As was only on the oxidized form (AsV), whereas the As release during the operations was mainly in reduced form (AsIII), which is more toxic for aquatic ecosystems.; Pour réduire le risque inondations causé par l'élévation du lit, des opérations de gestion sédimentaire sont menées régulièrement sur le Rhône pour évacuer les sédiments accumulés au cours du temps en amont des barrages. La hausse drastique des teneurs en matières en suspension (jusqu'à 15 g/L) suggère un possible relargage de contaminants. Afin d'évaluer la variabilité spatiale et temporelle des concentrations en métaux dissous lors de cet évènement, une stratégie d'échantillonnage combinant prélèvements ponctuels et déploiement d'échantillonneurs passifs de type DGT a été mise en place sur 3 sites. Le suivi temporel des métaux dissous a montré que les concentrations en Cd, Cu, Fe, Hg, Pb, et Zn n'étaient pas modifiées durant l'évènement, alors que celles en As, Co, Mn, Mo, Ni, Sb et U ont été multipliées de 2 à 22 fois. Ces contaminants dissous proviennent en partie des particules remobilisées, puisque ces hausses ne peuvent pas être expliquées par la seule contribution de l'eau interstitielle du sédiment. De plus, les mesures DGT ont confirmé les concentrations faibles et stables de Cu, Fe, Pb et Zn et montré pour As, Co, Mn et Ni un niveau moyenné reflétant l'augmentation des concentrations durant l'évènement. Enfin, les analyses de spéciation ont montré qu'avant l'évènement, l'As était présent uniquement sous forme oxydée (AsV), alors que l'apport d'As durant l'évènement était majoritairement sous forme réduite (AsIII), plus toxique pour l'écosystème aquatique.
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- 2018
50. Role of the great toe to improve postural control in elite women handball players
- Author
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Viseux, F., primary, Villeneuve, P., additional, Barbier, F., additional, Parreira, R., additional, and Lemaire, A., additional
- Published
- 2019
- Full Text
- View/download PDF
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