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Your search keyword '"Barrabés, José Antonio"' showing total 8 results
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8 results on '"Barrabés, José Antonio"'

1. Spontaneous reperfusion enhances succinate concentration in peripheral blood from stemi patients but its levels does not correlate with myocardial infarct size or area at risk

Author

Consegal, Marta, Barba, Ignasi, García del Blanco, Bruno, Otaegui, Imanol, Rodríguez-Palomares, José F., Martí, Gerard, Serra, Bernat, Bellera, Neus, Ojeda-Ramos, Manuel, Valente, Filipa, Carmona, Maria Ángeles, Miró-Casas, Elisabet, Sambola, Antonia, Lidón, Rosa María, Bañeras, Jordi, Barrabés, José Antonio, Rodríguez, Cristina, Benito, Begoña, Ruiz-Meana, Marisol, Inserte, Javier, Ferreira-González, Ignacio, and Rodríguez-Sinovas, Antonio

Published
2023
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2. Invasive Versus Conservative Strategy in Frail Patients With NSTEMI: The MOSCA-FRAIL Clinical Trial Study Design

Author

Sanchis, Juan, Ariza-Solé, Albert, Abu-Assi, Emad, Alegre, Oriol, Alfonso, Fernando, Barrabés, José Antonio, Baz, José Antonio, Carol, Antonio, Díez Villanueva, Pablo, García del Blanco, Bruno, Elízaga, Jaime, Fernandez, Eduard, García del Egido, Abel, García Picard, Joan, Gómez Blázquez, Iván, Gómez Hospital, Joan Antoni, Hernández-Antolín, Rosana, Llibre, Cinta, Marín, Francisco, Martí Sánchez, David, Martín, Roberto, Martínez Sellés, Manuel, Miñana, Gema, Morales Gallardo, María José, Núñez, Julio, Pérez de Prado, Armando, Pinar, Eduardo, Sanmartín, Marcelo, Sionis, Alessandro, Villa, Adolfo, Marrugat, Jaume, and Bueno, Héctor

Published
2019
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3. Estrategia invasiva frente a conservadora en pacientes frágiles con IAMSEST. Diseño del ensayo clínico MOSCA-FRAIL

Author

Sanchis, Juan, Ariza-Solé, Albert, Abu-Assi, Emad, Alegre, Oriol, Alfonso, Fernando, Barrabés, José Antonio, Baz, José Antonio, Carol, Antonio, Díez Villanueva, Pablo, García del Blanco, Bruno, Elízaga, Jaime, Fernandez, Eduard, García del Egido, Abel, García Picard, Joan, Gómez Blázquez, Iván, Gómez Hospital, Joan Antoni, Hernández-Antolín, Rosana, Llibre, Cinta, Marín, Francisco, Martí Sánchez, David, Martín, Roberto, Martínez Sellés, Manuel, Miñana, Gema, Morales Gallardo, María José, Núñez, Julio, Pérez de Prado, Armando, Pinar, Eduardo, Sanmartín, Marcelo, Sionis, Alessandro, Villa, Adolfo, Marrugat, Jaume, and Bueno, Héctor

Published
2019
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6. Sex bias in admission to tertiary‐care centres for acute myocardial infarction and cardiogenic shock

Author

Sambola, Antonia, primary, Elola, Francisco Javier, additional, Buera, Irene, additional, Fernández, Cristina, additional, Bernal, José Luis, additional, Ariza, Albert, additional, Brindis, Ralph, additional, Bueno, Héctor, additional, Rodríguez‐Padial, Luis, additional, Marín, Francisco, additional, Barrabés, José Antonio, additional, Hsia, Renee, additional, and Anguita, Manuel, additional

Published
2021
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8. Pre-treatment with the Na+/H+ exchange inhibitor cariporide delays cell-to-cell electrical uncoupling during myocardial ischemia

Author

Rodrıguez-Sinovas, Antonio, Garcıa-Dorado, David, Padilla, Ferran, Inserte, Javier, Barrabés, José Antonio, Ruiz-Meana, Marisol, Agulló, Luis, and Soler-Soler, Jordi

Subjects
GAP junctions (Cell biology), ISCHEMIA, REPERFUSION
Abstract

Objective: Inhibition of Na+–H+ exchange (NHE) delays the onset of myocardial rigor contracture during ischemia. The aim of this study was to analyse the effects of NHE inhibition on cell-to-cell electrical uncoupling during myocardial ischemia/reperfusion. Methods: Twenty-six isolated rat hearts and 23 in situ porcine hearts were submitted to no-flow ischemia followed by reperfusion, with or without pre-treatment with cariporide (7 μM in rats and 3 mg/kg in pigs). Ischemic rigor and hypercontracture, conduction velocity and myocardial electrical impedance were monitored. Results: Pre-treatment with cariporide delayed ATP depletion (luminescence assay in rat myocardium) and onset of rigor contracture (tension recordings or ultrasonic crystals) during ischemia both in rat and pig hearts (P<0.05). In addition, cariporide delayed the onset of sharp changes in tissue resistivity and phase angle in impedance recordings (four-electrode probes) from 10±1 to 13±1 min (P<0.001) in rat hearts, and from 22±1 to 38±2 min (P<0.001) in pigs. Blockade of impulse propagation (transmembrane action potentials in rat hearts) was also markedly delayed by cariporide (from 14±1 to 20±1 min, P<0.001). Reperfusion-induced LDH release in rat hearts and infarct size in pigs were markedly reduced by pre-treatment with cariporide. Conclusions: Inhibition of NHE with cariporide slows the progression of ischemic injury during myocardial ischemia, and delays the onset of cell-to-cell electrical uncoupling. [Copyright &y& Elsevier]

Published
2003
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