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1,159 results on '"Barreto, Mauricio L"'

1. Evaluating the relationship between conditional cash transfer programme on preterm births: a retrospective longitudinal study using the 100 million Brazilian cohort

Author

Ortelan, Naiá, de Almeida, Márcia Furquim, Pinto Júnior, Elzo Pereira, Bispo, Nivea, Fiaccone, Rosemeire L., Falcão, Ila Rocha, Rocha, Aline dos Santos, Ramos, Dandara, Paixão, Enny S., de Cássia Ribeiro-Silva, Rita, Rodrigues, Laura C., Barreto, Mauricio L., and Ichihara, Maria Yury T.

Published
2024
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3. Selecting Subpopulations for Causal Inference in Regression Discontinuity Designs

Author

Forastiere, Laura, Mattei, Alessandra, Pescarini, Julia M., Barreto, Mauricio L., and Mealli, Fabrizia

Subjects
Statistics - Methodology
Abstract

The Brazil Bolsa Familia (BF) program is a conditional cash transfer program aimed to reduce short-term poverty by direct cash transfers and to fight long-term poverty by increasing human capital among poor Brazilian people. Eligibility for Bolsa Familia benefits depends on a cutoff rule, which classifies the BF study as a regression discontinuity (RD) design. Extracting causal information from RD studies is challenging. Following Li et al (2015) and Branson and Mealli (2019), we formally describe the BF RD design as a local randomized experiment within the potential outcome approach. Under this framework, causal effects can be identified and estimated on a subpopulation where a local overlap assumption, a local SUTVA and a local ignorability assumption hold. We first discuss the potential advantages of this framework over local regression methods based on continuity assumptions, which concern the definition of the causal estimands, the design and the analysis of the study, and the interpretation and generalizability of the results. A critical issue of this local randomization approach is how to choose subpopulations for which we can draw valid causal inference. We propose a Bayesian model-based finite mixture approach to clustering to classify observations into subpopulations where the RD assumptions hold and do not hold. This approach has important advantages: a) it allows to account for the uncertainty in the subpopulation membership, which is typically neglected; b) it does not impose any constraint on the shape of the subpopulation; c) it is scalable to high-dimensional settings; e) it allows to target alternative causal estimands than the average treatment effect (ATE); and f) it is robust to a certain degree of manipulation/selection of the running variable. We apply our proposed approach to assess causal effects of the Bolsa Familia program on leprosy incidence in 2009.

Published
2022

5. Do social protection programmes affect the burden of breast and cervical cancer? A systematic review

Author

Gabrielli, Ligia, Alvim Matos, Sheila M., Luísa Patrão, Ana, Góes, Emanuelle F., da Conceição C. Almeida, Maria, M.S. Menezes, Greice, dos-Santos-Silva, Isabel, Azevedo e Silva, Gulnar, Teresa Bustamante-Teixeira, Maria, Barreto, Mauricio L., Vittal Katikireddi, Srinivasa, Leyland, Alastair H., Ferreira Campos, Luana, Maria Dias Fernandes de Novaes, Ester, de Almeida Pereira, Daniela, Rodrigues Santana, Elvira, Rodrigues Gonçalves Zeferino, Fernanda, Cleide da Silva Dias, Ana, Fernandes, Fábio G., Cristina de Oliveira Costa, Ana, and M.L. Aquino, Estela

Published
2024
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6. Genetics of Latin American Diversity Project: Insights into population genetics and association studies in admixed groups in the Americas

Author

Borda, Victor, Loesch, Douglas P., Guo, Bing, Laboulaye, Roland, Veliz-Otani, Diego, French, Jennifer N., Leal, Thiago Peixoto, Gogarten, Stephanie M., Ikpe, Sunday, Gouveia, Mateus H., Mendes, Marla, Abecasis, Gonçalo R., Alvim, Isabela, Arboleda-Bustos, Carlos E., Arboleda, Gonzalo, Arboleda, Humberto, Barreto, Mauricio L., Barwick, Lucas, Bezzera, Marcos A., Blangero, John, Borges, Vanderci, Caceres, Omar, Cai, Jianwen, Chana-Cuevas, Pedro, Chen, Zhanghua, Custer, Brian, Dean, Michael, Dinardo, Carla, Domingos, Igor, Duggirala, Ravindranath, Dieguez, Elena, Fernandez, Willian, Ferraz, Henrique B., Gilliland, Frank, Guio, Heinner, Horta, Bernardo, Curran, Joanne E., Johnsen, Jill M., Kaplan, Robert C., Kelly, Shannon, Kenny, Eimear E., Konkle, Barbara A., Kooperberg, Charles, Lescano, Andres, Lima-Costa, M. Fernanda, Loos, Ruth J.F., Manichaikul, Ani, Meyers, Deborah A., Naslavsky, Michel S., Nickerson, Deborah A., North, Kari E., Padilla, Carlos, Preuss, Michael, Raggio, Victor, Reiner, Alexander P., Rich, Stephen S., Rieder, Carlos R., Rienstra, Michiel, Rotter, Jerome I., Rundek, Tatjana, Sacco, Ralph L., Sanchez, Cesar, Sankaran, Vijay G., Santos-Lobato, Bruno Lopes, Schumacher-Schuh, Artur Francisco, Scliar, Marilia O., Silverman, Edwin K., Sofer, Tamar, Lasky-Su, Jessica, Tumas, Vitor, Weiss, Scott T., Mata, Ignacio F., Hernandez, Ryan D., Tarazona-Santos, Eduardo, and O’Connor, Timothy D.

Published
2024
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8. The impact of primary health care on AIDS incidence and mortality: A cohort study of 3.4 million Brazilians

Author

Pinto, Priscila F. P. S., Macinko, James, Silva, Andréa F., Lua, Iracema, Jesus, Gabriela, Magno, Laio, Santos, Carlos A. S. Teles, Ichihara, Maria Yury, Barreto, Mauricio L., Moucheraud, Corrina, Souza, Luis E., Dourado, Inês, and Rasella, Davide

Subjects
Mortality -- Brazil, Primary health care -- Health aspects -- Analysis, AIDS (Disease) -- Health aspects -- Analysis, Biological sciences
Abstract

Background Primary Health Care (PHC) is essential for effective, efficient, and more equitable health systems for all people, including those living with HIV/AIDS. This study evaluated the impact of the exposure to one of the largest community-based PHC programs in the world, the Brazilian Family Health Strategy (FHS), on AIDS incidence and mortality. Methods and findings A retrospective cohort study carried out in Brazil from January 1, 2007 to December 31, 2015. We conducted an impact evaluation using a cohort of 3,435,068 [greater than or equal to]13 years low-income individuals who were members of the 100 Million Brazilians Cohort, linked to AIDS diagnoses and deaths registries. We evaluated the impact of FHS on AIDS incidence and mortality and compared outcomes between residents of municipalities with low or no FHS coverage (unexposed) with those in municipalities with 100% FHS coverage (exposed). We used multivariable Poisson regressions adjusted for all relevant municipal and individual-level demographic, socioeconomic, and contextual variables, and weighted with inverse probability of treatment weighting (IPTW). We also estimated the FHS impact by sex and age and performed a wide range of sensitivity and triangulation analyses; 100% FHS coverage was associated with lower AIDS incidence (rate ratio [RR]: 0.76, 95% CI: 0.68 to 0.84) and mortality (RR: 0.68, 95%CI: 0.56 to 0.82). FHS impact was similar between men and women, but was larger in people aged [greater than or equal to]35 years old both for incidence (RR: 0.62, 95% CI: 0.53 to 0.72) and mortality (RR: 0.56, 95% CI: 0.43 to 0.72). The absence of important confounding variables (e.g., sexual behavior) is a key limitation of this study. Conclusions AIDS should be an avoidable outcome for most people living with HIV today and our study shows that FHS coverage could significantly reduce AIDS incidence and mortality among low-income populations in Brazil. Universal access to comprehensive healthcare through community-based PHC programs should be promoted to achieve the Sustainable Development Goals of ending AIDS by 2030., Author(s): Priscila F. P. S. Pinto 1,2, James Macinko 3, Andréa F. Silva 1,2, Iracema Lua 1,2, Gabriela Jesus 1,2, Laio Magno 4, Carlos A. S. Teles Santos 2, Maria [...]

Published
2024
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9. Gut microbiome signature and nasal lavage inflammatory markers in young people with asthma

Author

Sampaio Dotto Fiuza, Bianca, Machado de Andrade, Candace, Meirelles, Pedro Milet, Santos da Silva, Jorley, de Jesus Silva, Milca, Vila Nova Santana, Cinthia, Pimentel Pinheiro, Gabriela, Mpairwe, Harriet, Cooper, Philip, Brooks, Collin, Pembrey, Lucy, Taylor, Steven, Douwes, Jeroen, Cruz, Álvaro A., Barreto, Mauricio L., Pearce, Neil, and Figueiredo, Camila A.V.

Published
2024
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23. The effects of social determinants of health on acquired immune deficiency syndrome in a low-income population of Brazil: a retrospective cohort study of 28.3 million individuals

Author

Lua, Iracema, Silva, Andrea F., Guimarães, Nathalia S., Magno, Laio, Pescarini, Julia, Anderle, Rodrigo V.R., Ichihara, Maria Yury, Barreto, Mauricio L., Teles Santos, Carlos A.S., Chenciner, Louisa, Souza, Luis Eugênio, Macinko, James, Dourado, Ines, and Rasella, Davide

Published
2023
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25. A multinational Delphi consensus to end the COVID-19 public health threat

Author

Lazarus, Jeffrey V., Romero, Diana, Kopka, Christopher J., Karim, Salim Abdool, Abu-Raddad, Laith J., Almeida, Gisele, Baptista-Leite, Ricardo, Barocas, Joshua A., Barreto, Mauricio L., Bar-Yam, Yaneer, Bassat, Quique, Batista, Carolina, Bazilian, Morgan, Chiou, Shu-Ti, del Rio, Carlos, Dore, Gregory J., Gao, George F., Gostin, Lawrence O., Hellard, Margaret, Jimenez, Jose L., Kang, Gagandeep, Lee, Nancy, Matičič, Mojca, McKee, Martin, Nsanzimana, Sabin, Oliu-Barton, Miquel, Pradelski, Bary, Pyzik, Oksana, Rabin, Kenneth, Raina, Sunil, Rashid, Sabina Faiz, Rathe, Magdalena, Saenz, Rocio, Singh, Sudhvir, Trock-Hempler, Malene, Villapol, Sonia, Yap, Peiling, Binagwaho, Agnes, Kamarulzaman, Adeeba, and El-Mohandes, Ayman

Published
2022
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31. Vaccine effectiveness of two-dose BNT162b2 against symptomatic and severe COVID-19 among adolescents in Brazil and Scotland over time: a test-negative case-control study

Author

Florentino, Pilar T V, Millington, Tristan, Cerqueira-Silva, Thiago, Robertson, Chris, de Araújo Oliveira, Vinicius, Júnior, Juracy B S, Alves, Flávia J O, Penna, Gerson O, Vital Katikireddi, Srinivasa, Boaventura, Viviane S, Werneck, Guilherme L, Pearce, Neil, McCowan, Colin, Sullivan, Christopher, Agrawal, Utkarsh, Grange, Zoe, Ritchie, Lewis D, Simpson, Colin R, Sheikh, Aziz, Barreto, Mauricio L, Rudan, Igor, Barral-Netto, Manoel, and Paixão, Enny S

Published
2022
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33. Effectiveness of CoronaVac, ChAdOx1 nCoV-19, BNT162b2, and Ad26.COV2.S among individuals with previous SARS-CoV-2 infection in Brazil: a test-negative, case-control study

Author

Cerqueira-Silva, Thiago, Andrews, Jason R, Boaventura, Viviane S, Ranzani, Otavio T, de Araújo Oliveira, Vinicius, Paixão, Enny S, Júnior, Juracy Bertoldo, Machado, Tales Mota, Hitchings, Matt D T, Dorion, Murilo, Lind, Margaret L, Penna, Gerson O, Cummings, Derek A T, Dean, Natalie E, Werneck, Guilherme Loureiro, Pearce, Neil, Barreto, Mauricio L, Ko, Albert I, Croda, Julio, and Barral-Netto, Manoel

Published
2022
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37. Two-dose ChAdOx1 nCoV-19 vaccine protection against COVID-19 hospital admissions and deaths over time: a retrospective, population-based cohort study in Scotland and Brazil

Author

Katikireddi, Srinivasa Vittal, Cerqueira-Silva, Thiago, Vasileiou, Eleftheria, Robertson, Chris, Amele, Sarah, Pan, Jiafeng, Taylor, Bob, Boaventura, Viviane, Werneck, Guilherme Loureiro, Flores-Ortiz, Renzo, Agrawal, Utkarsh, Docherty, Annemarie B, McCowan, Colin, McMenamin, Jim, Moore, Emily, Ritchie, Lewis D, Rudan, Igor, Shah, Syed Ahmar, Shi, Ting, Simpson, Colin R, Barreto, Mauricio L, Oliveira, Vinicius de Araujo, Barral-Netto, Manoel, and Sheikh, Aziz

Published
2022
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38. CoronaVac vaccine is effective in preventing symptomatic and severe COVID-19 in pregnant women in Brazil: a test-negative case-control study

Author

Paixao, Enny S., Wong, Kerry L. M., Alves, Flavia Jôse Oliveira, de Araújo Oliveira, Vinicius, Cerqueira-Silva, Thiago, Júnior, Juracy Bertoldo, Machado, Tales Mota, Junior, Elzo Pereira Pinto, Boaventura, Viviane S., Penna, Gerson O., Werneck, Guilherme Loureiro, Rodrigues, Laura C., Pearce, Neil, Barreto, Mauricio L., and Barral-Netto, Manoel

Published
2022
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39. Author Correction: Whole-genome sequencing of 1,171 elderly admixed individuals from Brazil

Author

Naslavsky, Michel S., Scliar, Marilia O., Yamamoto, Guilherme L., Wang, Jaqueline Yu Ting, Zverinova, Stepanka, Karp, Tatiana, Nunes, Kelly, Ceroni, José Ricardo Magliocco, de Carvalho, Diego Lima, da Silva Simões, Carlos Eduardo, Bozoklian, Daniel, Nonaka, Ricardo, dos Santos Brito Silva, Nayane, da Silva Souza, Andreia, de Souza Andrade, Heloísa, Passos, Marília Rodrigues Silva, Castro, Camila Ferreira Bannwart, Mendes-Junior, Celso T., Mercuri, Rafael L. V., Miller, Thiago L. A., Buzzo, Jose Leonel, Rego, Fernanda O., Araújo, Nathalia M., Magalhães, Wagner C. S., Mingroni-Netto, Regina Célia, Borda, Victor, Guio, Heinner, Rojas, Carlos P., Sanchez, Cesar, Caceres, Omar, Dean, Michael, Barreto, Mauricio L., Lima-Costa, Maria Fernanda, Horta, Bernardo L., Tarazona-Santos, Eduardo, Meyer, Diogo, Galante, Pedro A. F., Guryev, Victor, Castelli, Erick C., Duarte, Yeda A. O., Passos-Bueno, Maria Rita, and Zatz, Mayana

Published
2022
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41. Population-based surveillance for congenital zika virus syndrome: a latent class analysis of recorded cases from 2015–2018

Author

Paixao, Enny S., Rodrigues, Laura C., Costa, Maria da Conceição N., de Carvalho-Sauer, Rita de Cassia Oliveira, Oliveira, Wanderson K., Cardim, Luciana L., Schuler-Faccini, Lavinia, Andrade, Roberto F. S., Rodrigues, Moreno S., Brickley, Elizabeth B., Veiga, Rafael V., Costa, Larissa C., Carmo, Eduardo H., Smeeth, Liam, Barreto, Mauricio L., and Teixeira, Maria Gloria

Published
2022
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43. Whole-genome sequencing of 1,171 elderly admixed individuals from Brazil

Author

Naslavsky, Michel S., Scliar, Marilia O., Yamamoto, Guilherme L., Wang, Jaqueline Yu Ting, Zverinova, Stepanka, Karp, Tatiana, Nunes, Kelly, Ceroni, José Ricardo Magliocco, de Carvalho, Diego Lima, da Silva Simões, Carlos Eduardo, Bozoklian, Daniel, Nonaka, Ricardo, dos Santos Brito Silva, Nayane, da Silva Souza, Andreia, de Souza Andrade, Heloísa, Passos, Marília Rodrigues Silva, Castro, Camila Ferreira Bannwart, Mendes-Junior, Celso T., Mercuri, Rafael L. V., Miller, Thiago L. A., Buzzo, Jose Leonel, Rego, Fernanda O., Araújo, Nathalia M., Magalhães, Wagner C. S., Mingroni-Netto, Regina Célia, Borda, Victor, Guio, Heinner, Rojas, Carlos P., Sanchez, Cesar, Caceres, Omar, Dean, Michael, Barreto, Mauricio L., Lima-Costa, Maria Fernanda, Horta, Bernardo L., Tarazona-Santos, Eduardo, Meyer, Diogo, Galante, Pedro A. F., Guryev, Victor, Castelli, Erick C., Duarte, Yeda A. O., Passos-Bueno, Maria Rita, and Zatz, Mayana

Published
2022
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44. Wildfire, deforestation and health in tropical rainforest areas: a scoping review protocol

Author

Casais, Gustavo, primary, Guimarães, Nathalia Sernizon, additional, Cortes, Taísa Rodrigues, additional, Pescarini, Julia, additional, Rebouças de Magalhães, Poliana, additional, Wells, Valerie, additional, de Sousa Filho, José Firmino, additional, Delgado Neves, Danielson Jorge, additional, Shimonovich, Michal, additional, Olsen, Jonathan R, additional, de Carvalho Neto, Edgar Marcelino, additional, Cooper, Philip, additional, Katikireddi, Srinivasa Vittal, additional, Emanuel, Lucas, additional, Andrade, Roberto F S, additional, Ferreira dos Santos, Gervasio, additional, and Barreto, Mauricio L, additional

Published
2024
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45. Genome-wide association study of asthma, total IgE, and lung function in a cohort of Peruvian children

Author

Akenroye, Ayobami T., Brunetti, Tonya, Romero, Karina, Daya, Michelle, Kanchan, Kanika, Shankar, Gautam, Chavan, Sameer, Preethi Boorgula, Meher, Ampleford, Elizabeth A., Fonseca, Héllen Freitas, Hawkins, Gregory A., Pitangueira Teixeira, Helena Mariana, Campbell, Monica, Rafaels, Nicholas, Winters, Alexandra, Bleecker, Eugene R., Cruz, Alvaro A., Barreto, Mauricio L., Meyers, Deborah A., Ortega, Victor E., Figueiredo, Camila A., Barnes, Kathleen C., Checkley, William, Hansel, Nadia N., and Mathias, Rasika A.

Published
2021
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46. Risk of mortality for small newborns in Brazil, 2011-2018: A national birth cohort study of 17.6 million records from routine register-based linked data

Author

Paixao, Enny S., Blencowe, Hannah, Falcao, Ila Rocha, Ohuma, Eric O., Rocha, Aline dos Santos, Alves, Flávia Jôse Oliveira, Costa, Maria da Conceição N., Suárez-Idueta, Lorena, Ortelan, Naiá, Smeeth, Liam, Rodrigues, Laura C., Lawn, Joy E, de Almeida, Marcia Furquim, Ichihara, Maria Yury, Silva, Rita de Cássia Ribeiro, Teixeira, Maria Gloria, and Barreto, Mauricio L.

Published
2021
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50. Mortality in children under 5 years of age with congenital syphilis in Brazil: A nationwide cohort study

Author

Paixao, Enny S., Ferreira, Andrêa JF, dos Santos, Idália Oliveira, Rodrigues, Laura C., Fiaccone, Rosemeire, Salvi, Leonardo, de Oliveira, Guilherme Lopes, Santana, José Guilherme, Cardoso, Andrey Moreira, Teles, Carlos Antônio de S. S., Soares, Maria Auxiliadora, Amaral, Eliana, Smeeth, Liam, Barreto, Mauricio L., and Ichihara, Maria Yury

Subjects
Biological sciences
Abstract

Background Congenital syphilis (CS) is a major and avoidable cause of neonatal death worldwide. In this study, we aimed to estimate excess all-cause mortality in children under 5 years with CS compared to those without CS. Methods and findings In this population-based cohort study, we used linked, routinely collected data from Brazil from January 2011 to December 2017. Cox survival models were adjusted for maternal region of residence, maternal age, education, material status, self-declared race and newborn sex, and year of birth and stratified according to maternal treatment status, non-treponemal titers and presence of signs and symptoms at birth. Over 7 years, a total of 20 057 013 live-born children followed up (through linkage) to 5 years of age, 93 525 were registered with CS, and 2 476 died. The all-cause mortality rate in the CS group was 7·84/1 000 person-years compared with 2·92/1 000 person-years in children without CS, crude hazard ratio (HR) = 2·41 (95% CI 2·31 to 2·50). In the fully adjusted model, the highest under-five mortality risk was observed among children with CS from untreated mothers HR = 2·82 (95% CI 2·63 to 3·02), infants with non-treponemal titer higher than 1:64 HR = 8·87 (95% CI 7·70 to 10·22), and children with signs and symptoms at birth HR = 7·10 (95% CI 6·60 to 7·63). Among children registered with CS, CS was recorded as the underlying cause of death in 33% (495/1 496) of neonatal, 11% (85/770) of postneonatal, and 2·9% (6/210) of children 1 year of age. The main limitations of this study were the use of a secondary database without additional clinical information and the potential misclassification of exposure status. Conclusions This study showed an increased mortality risk among children with CS that goes beyond the first year of life. It also reinforces the importance of maternal treatment that infant non-treponemal titers and the presence of signs and symptoms of CS at birth are strongly associated with subsequent mortality. Trial registration Observational study., Author(s): Enny S. Paixao 1,2,*, Andrêa JF Ferreira 2, Idália Oliveira dos Santos 2, Laura C. Rodrigues 1,2, Rosemeire Fiaccone 2,3, Leonardo Salvi 2, Guilherme Lopes de Oliveira 2,4, José [...]

Published
2023
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