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444 results on '"Barrientos, J"'

1. Efficiency calibration of the BRIKEN detector: the world largest counter for beta-delayed neutrons

Author

Pallas, M., Tarifeno-Saldivia, A., Calvino, F., Mont-Geli, N., Tain, J. L., Tolosa-Delgado, A., Agramunt, J., Molina, F., Aguilera, P., and Romero-Barrientos, J.

Subjects
Physics - Instrumentation and Detectors
Abstract

Beta-delayed neutron emission plays a fundamental role in the explosive nucleosynthesis of elements heavier than iron by the rapid neutron capture (r-process). The most ambitious project related to beta-delayed neutron detection of very exotic nuclei is carried out by the BRIKEN collaboration at RIKEN Nishima Center. In this work, a brief description of the BRIKEN project is presented. A methodology for the precise characterization of the BRIKEN neutron counter efficiency, for fast neutrons, using an uncalibrated 252Cf neutron source is described. The method relies on the well-known neutron multiplicity distribution of such source and correlation counting method. A detailed experimental study with the BRIKEN neutron counter and a 252 Cf neutron source at the RIKEN Nishina center is presented. The result of this work is the determination of the neutron detection efficiency of the BRIKEN neutron counter with high accuracy., Comment: Proceedings del XXII Simposio Chileno de Fisica, 2020, submitted ato Journal of Physics: Conference Series

Published
2022

5. Narnaviruses: novel players in fungal–bacterial symbioses

Author

Espino-Vázquez, Astrid N, Bermúdez-Barrientos, J Roberto, Cabrera-Rangel, J Francisco, Córdova-López, Gonzalo, Cardoso-Martínez, Faviola, Martínez-Vázquez, Azul, Camarena-Pozos, David A, Mondo, Stephen J, Pawlowska, Teresa E, Abreu-Goodger, Cei, and Partida-Martínez, Laila P

Subjects
Microbiology, Biological Sciences, Ecology, Infectious Diseases, Emerging Infectious Diseases, Aetiology, 2.2 Factors relating to the physical environment, Infection, Zero Hunger, Burkholderia, Rhizopus, Spores, Fungal, Symbiosis, Environmental Sciences, Technology, Biological sciences, Environmental sciences
Abstract

Rhizopus microsporus is an early-diverging fungal species with importance in ecology, agriculture, food production, and public health. Pathogenic strains of R. microsporus harbor an intracellular bacterial symbiont, Mycetohabitans (formerly named Burkholderia). This vertically transmitted bacterial symbiont is responsible for the production of toxins crucial to the pathogenicity of Rhizopus and remarkably also for fungal reproduction. Here we show that R. microsporus can live not only in symbiosis with bacteria but also with two viral members of the genus Narnavirus. Our experiments revealed that both viruses replicated similarly in the growth conditions we tested. Viral copies were affected by the developmental stage of the fungus, the substrate, and the presence or absence of Mycetohabitans. Absolute quantification of narnaviruses in isolated asexual sporangiospores and sexual zygospores indicates their vertical transmission. By curing R. microsporus of its viral and bacterial symbionts and reinfecting bacteria to reestablish symbiosis, we demonstrate that these viruses affect fungal biology. Narnaviruses decrease asexual reproduction, but together with Mycetohabitans, are required for sexual reproductive success. This fungal-bacterial-viral system represents an outstanding model to investigate three-way microbial symbioses and their evolution.

Published
2020

8. Leukemia-cell proliferation and disease progression in patients with early stage chronic lymphocytic leukemia

Author

Murphy, EJ, Neuberg, DS, Rassenti, LZ, Hayes, G, Redd, R, Emson, C, Li, K, Brown, JR, Wierda, WG, Turner, S, Greaves, AW, Zent, CS, Byrd, JC, McConnel, C, Barrientos, J, Kay, N, Hellerstein, MK, Chiorazzi, N, Kipps, TJ, and Rai, KR

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cancer, Lymphoma, Lymphatic Research, Rare Diseases, Hematology, Clinical Research, Genetics, Adult, Aged, Aged, 80 and over, Biomarkers, Tumor, Cell Proliferation, Disease Progression, Female, Follow-Up Studies, Humans, Leukemia, Lymphocytic, Chronic, B-Cell, Male, Middle Aged, Mutation, Neoplasm Staging, Prognosis, Prospective Studies, Survival Rate, Clinical Sciences, Immunology, Cardiovascular medicine and haematology, Clinical sciences, Oncology and carcinogenesis
Abstract

The clinical course of patients with recently diagnosed early stage chronic lymphocytic leukemia (CLL) is highly variable. We examined the relationship between CLL-cell birth rate and treatment-free survival (TFS) in 97 patients with recently diagnosed, Rai stage 0-II CLL in a blinded, prospective study, using in vivo 2H2O labeling. Birth rates ranged from 0.07 to 1.31% new cells per day. With median follow-up of 4.0 years, 33 subjects (34%) required treatment by NCI criteria. High-birth rate was observed in 44% of subjects and was significantly associated with shorter TFS, unmutated IGHV status and expression of ZAP70 and of CD38. In multivariable modeling considering age, gender, Rai stage, expression of ZAP70 or CD38, IGHV mutation status and FISH cytogenetics, only CLL-cell birth rate and IGHV mutation status met criteria for inclusion. Hazard ratios were 3.51 (P=0.002) for high-birth rate and 4.93 (P

Published
2017

11. Study of decay properties of Ba to Nd nuclei (A~160) relevant to the formation of the r-process rare-earth peak

Author

Pallàs M., Tarifeño-Saldivia A., Kiss G. G., Tain J. L., Tolosa-Delgado A., Vitéz-Sveiczer A., Calviño F., Agramunt J., Aguilera P., Algora A., Allmond J. M., Baba H., Brewer N. T., Caballero-Folch R., Coleman-Smith P. J., Cortes G., Davinson T., Dillmann I., Domingo-Pardo C., Estrade A., Fukuda N., Go S., Griffin C. J., Grzywacz R. K., Hall O., Harkness-Brennan L. J., Isobe T., Kahl D., King T. T., Korgul A., Kovács S., Kubono S., Labiche M., Liu J., Madurga M., Miernik K., Molina F., Mont-Geli N., Morales A. I., Nácher E., Navarro A., Nepal N., Nishimura S., Piersa-Silkowska M., Phong V., Rasco B. C., Romero-Barrientos J., Rubio B., Rykaczewski K. P., Saito Y., Sakurai H., Shimizu Y., Singh M., Sumikama T., Suzuki H., Szegedi T. N., Takeda H., Wang K., Wolińska-Cichocka M., Woods P. J., and Yokoyama R.

Subjects
Physics, QC1-999
Abstract

Half-lifes (T1/2) of exotic neutron-rich isotopes of Ba, La, Ce, Pr, and Nd were measured at the RIKEN Nishina Center. The experimental setup consisted of the BigRIPS in-flight separator for ion selection identification, the Advance Implantation Detector Array (AIDA) for ions and β detection, and the BRIKEN detector for neutron counting. Using this setup, 4 new T1/2 have been measured for the first time, and 38 T1/2 have been remeasured with improved precision in several cases. These new experimental data should help to constrain theoretical models for calculations of T1/2. The status of the experimental analysis and preliminary results are provided in this contribution.

Published
2023
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12. Study of decay properties for Ba to Nd nuclei relevant for the formation of the r-process rare-earth peak (A∼160)

Author

Pallàs M., Tarifeño-Saldivia A., Kiss G. G., Tain J. L., Tolosa-Delgado A., Vitéz-Sveiczer A., Calviño F., Agramunt J., Aguilera P., Algora A., Allmond J. M., Baba H., Brewer N. T., Caballero-Folch R., Coleman-Smith P. J., Cortes G., Davinson T., Dillmann I., Domingo-Pardo C., Estrade A., Fukuda N., Go S., Griffin C. J., Grzywacz R. K., Hall O., Harkness-Brennan L. J., Isobe T., Kahl D., King T. T., Korgul A., Kovács S., Kubono S., Labiche M., Liu J., Madurga M., Miernik K., Molina F., Mont-Geli N., Morales A. I., Nácher E., Navarro A., Nepal N., Nishimura S., Piersa-Silkowska M., Phong V., Rasco B. C., Romero-Barrientos J., Rubio B., Rykaczewski K. P., Saito Y., Sakurai H., Shimizu Y., Singh M., Sumikama T., Suzuki H., Szegedi T. N., Takeda H., Wang K., Wolińska-Cichocka M., Woods P. J., and Yokoyama R.

Subjects
Physics, QC1-999
Abstract

At the RIKEN Nishina Center, exotic neutron-rich isotopes of Ba, La, Ce, Pr, and Nd were measured. This work reports their half-lives (T1/2) and β-delayed neutron-emission probabilities (Pxn). The setup consisted of the BigRIPS in-flight separator for particle identification, the Advanced Implantation Detector Array (AIDA) for ions and β detection, and the BRIKEN neutron counter for neutron detection. Using this arrangement, 4 new T1/2 and 14 new P1n were measured. Furthermore, 38 T1/2 and 2 P1n values were remeasured, decreasing the uncertainties for some of them. In addition to improving predictions of nucleosynthesis models that describe the production of the rare-earth peak at A ∼ 160 via the r-process, these additional experimental data should help to constrain theoretical models for calculations of T1/2 and Pxn in this region.

Published
2023
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14. Formation of Common Investment Networks by Project Establishment between Agents

Author

Navarro-Barrientos, J. -Emeterio

Subjects
Computer Science - Social and Information Networks, Computer Science - Computational Engineering, Finance, and Science
Abstract

We present an investment model integrated with trust-reputation mechanisms where agents interact with each other to establish investment projects. We investigate the establishment of investment projects, the influence of the interaction between agents in the evolution of the distribution of wealth, as well as the formation of common investment networks and some of their properties. Simulation results show that the wealth distribution presents a power law in its tail. Also, it is shown that the trust and reputation mechanism presented leads to the establishment of networks among agents, which present some of the typical characteristics of real-life networks like a high clustering coefficient and short average path length.

Published
2011
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15. Risk-Seeking versus Risk-Avoiding Investments in Noisy Periodic Environments

Author

Barrientos, J. Emeterio Navarro, Walter, Frank E., and Schweitzer, Frank

Subjects
Quantitative Finance - Portfolio Management, Computer Science - Computational Engineering, Finance, and Science, Physics - Physics and Society
Abstract

We study the performance of various agent strategies in an artificial investment scenario. Agents are equipped with a budget, $x(t)$, and at each time step invest a particular fraction, $q(t)$, of their budget. The return on investment (RoI), $r(t)$, is characterized by a periodic function with different types and levels of noise. Risk-avoiding agents choose their fraction $q(t)$ proportional to the expected positive RoI, while risk-seeking agents always choose a maximum value $q_{max}$ if they predict the RoI to be positive ("everything on red"). In addition to these different strategies, agents have different capabilities to predict the future $r(t)$, dependent on their internal complexity. Here, we compare 'zero-intelligent' agents using technical analysis (such as moving least squares) with agents using reinforcement learning or genetic algorithms to predict $r(t)$. The performance of agents is measured by their average budget growth after a certain number of time steps. We present results of extensive computer simulations, which show that, for our given artificial environment, (i) the risk-seeking strategy outperforms the risk-avoiding one, and (ii) the genetic algorithm was able to find this optimal strategy itself, and thus outperforms other prediction approaches considered., Comment: 27 pp. v2 with minor corrections. See http://www.sg.ethz.ch for more info

Published
2008
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21. Zilovertamab vedotin (MK‐2140) in relapsed or refractory (R/R) non‐Hodgkin lymphoma (NHL): 14‐month follow‐up of the phase 1 waveLINE‐001 study

Author

Wang, M. L., primary, Mei, M., additional, Barr, P. M., additional, Barrientos, J. C., additional, de Vos, S., additional, Furman, R. R., additional, Patel, K., additional, Wierda, W. G., additional, Choi, M. Y., additional, Kallam, A., additional, Wang, S., additional, Ogbu, U. C., additional, Marinello, P., additional, and Spurgeon, S. E., additional

Published
2023
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31. Half-life Measurement Using Implant-\((\beta -\gamma )\) Time Correlations in the Region of Neutron-rich Lanthanides

Author

Vitéz-Sveiczer, A., primary, Kovács, S., additional, Kiss, G.G., additional, Saito, Y., additional, Tarifeño-Saldivia, A., additional, Pallas, M., additional, Tain, J.L., additional, Dillmann, I., additional, Agramunt, J., additional, Algora, A., additional, Domingo-Pardo, C., additional, Estrade, A., additional, Appleton, C., additional, Allmond, J.M., additional, Aguilera, P., additional, Baba, H., additional, Brewer, N.T., additional, Bruno, C., additional, Caballero-Folch, R., additional, Calvino, F., additional, Coleman-Smith, P.J., additional, Cortes, G., additional, Davinson, T., additional, Fukuda, N., additional, Ge, Z., additional, Go, S., additional, Griffin, C.J., additional, Grzywacz, R.K., additional, Hall, O., additional, Horváth, A., additional, Ha, J., additional, Harkness-Brennan, L.J., additional, Isobe, T., additional, Kahl, D., additional, King, T.T., additional, Korgul, A., additional, Krücken, R., additional, Kubono, S., additional, Labiche, M., additional, Liu, J., additional, Liang, J., additional, Madurga, M., additional, Miernik, K., additional, Molina, F., additional, Morales, A.I., additional, Mumpower, M.R., additional, Nacher, E., additional, Navarro, A., additional, Nepal, N., additional, Nishimura, S., additional, Piersa-Siłkowska, M., additional, Phong, V., additional, Rasco, B.C., additional, Rubio, B., additional, Rykaczewski, K.P., additional, Romero-Barrientos, J., additional, Sakurai, H., additional, Sexton, L., additional, Shimizu, Y., additional, Singh, M., additional, Sprouse, T., additional, Sumikama, T., additional, Surman, R., additional, Suzuki, H., additional, Szegedi, T.N., additional, Takeda, H., additional, Tolosa-Delgado, A., additional, Wang, K., additional, Wolinska-Cichocka, M., additional, Woods, P., additional, Yokoyama, R., additional, and Xu, Z., additional

Published
2023
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32. A Dynamical Systems Model for Understanding Behavioral Interventions for Weight Loss

Author

Navarro-Barrientos, J. -Emeterio, Rivera, Daniel E., Collins, Linda M., Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Chai, Sun-Ki, editor, Salerno, John J., editor, and Mabry, Patricia L., editor

Published
2010
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35. A Kohonen Network for Modeling Students’ Learning Styles in Web 2.0 Collaborative Learning Systems

Author

Zatarain-Cabada, Ramón, Barrón-Estrada, M. Lucia, Zepeda-Sánchez, Leopoldo, Sandoval, Guillermo, Osorio-Velazquez, J. Moises, Urias-Barrientos, J. E., Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Goebel, Randy, editor, Siekmann, Jörg, editor, Wahlster, Wolfgang, editor, Aguirre, Arturo Hernández, editor, Borja, Raúl Monroy, editor, and Garciá, Carlos Alberto Reyes, editor

Published
2009
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37. Effect of feeding type and artisanal process in microstructural and physicochemical parameters of fresh and ripened goat cheese

Author

Ramírez-Rivera, E. J., Jose Andres Herrera-Corredor, Toledo-López, V. M., Sauri-Duch, E., Rodriguez-Miranda, J., Juárez-Barrientos, J. M., Díaz-Rivera, P., and Herman-Lara, E.

Abstract

The objective of the present work was to determine the influence of feeding type and artisanal process on microstructural and physicochemical parameters of goat cheeses. The cheeses were made with goat's milk from goats which were fed with different forages: (1) reed (Cissu verticillata) and King grass (Saccharum sinense), (2) mulberry (Morus alba) leaves and orange (Citrus sinensis) peels, (3) alfalfa (Medicago sativa) and corn (Zea mays) stover, and (4) bellota (Quercus ilex) and Kikuyu grass (Pennisetum clandestinum). Fresh and ripened artisanal cheeses were analysed by scanning electron microscopy and image analysis. Results showed that goat’s milk of goats fed with mulberry leaves and orange peels generated larger conglomerates of fat in both types of cheeses, while the microstructure of the rest of the cheeses presented protein networks. A low pH and moisture content contributed to the formation of lactose crystals which ended in a compact microstructure, propitiating, reduction of the number of pores, porosity, and increase in the breakability of ripened cheeses. Pores of elongated shapes with irregular edges characterised the microstructure of both kinds of cheeses. Through discriminant analysis, it was found that the effect of the type of cheese and type of goat feeding influenced the microstructural and physicochemical parameters such as pore number, porosity, pore size, pore perimeter, roundness, FF, AR, SOL, tortuosity, INP-DI, PAZ, fat, moisture, and pH.

Published
2021
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38. Measuring the β-decay Properties of Neutron-rich Exotic Pm, Sm, Eu, and Gd Isotopes to Constrain the Nucleosynthesis Yields in the Rare-earth Region

Author

Kiss, G. G., primary, Vitéz-Sveiczer, A., additional, Saito, Y., additional, Tarifeño-Saldivia, A., additional, Pallas, M., additional, Tain, J. L., additional, Dillmann, I., additional, Agramunt, J., additional, Algora, A., additional, Domingo-Pardo, C., additional, Estrade, A., additional, Appleton, C., additional, Allmond, J. M., additional, Aguilera, P., additional, Baba, H., additional, Brewer, N. T., additional, Bruno, C., additional, Caballero-Folch, R., additional, Calvino, F., additional, Coleman-Smith, P. J., additional, Cortes, G., additional, Davinson, T., additional, Fukuda, N., additional, Ge, Z., additional, Go, S., additional, Griffin, C. J., additional, Grzywacz, R. K., additional, Hall, O., additional, Horváth, A., additional, Ha, J., additional, Harkness-Brennan, L. J., additional, Isobe, T., additional, Kahl, D., additional, King, T. T., additional, Korgul, A., additional, Kovács, S., additional, Krücken, R., additional, Kubono, S., additional, Labiche, M., additional, Liu, J., additional, Liang, J., additional, Madurga, M., additional, Miernik, K., additional, Molina, F., additional, Morales, A. I., additional, Mumpower, M. R., additional, Nacher, E., additional, Navarro, A., additional, Nepal, N., additional, Nishimura, S., additional, Piersa-Siłkowska, M., additional, Phong, V., additional, Rasco, B. C., additional, Rubio, B., additional, Rykaczewski, K. P., additional, Romero-Barrientos, J., additional, Sakurai, H., additional, Sexton, L., additional, Shimizu, Y., additional, Singh, M., additional, Sprouse, T., additional, Sumikama, T., additional, Surman, R., additional, Suzuki, H., additional, Szegedi, T. N., additional, Takeda, H., additional, Tolosa, A., additional, Wang, K., additional, Wolinska-Cichocka, M., additional, Woods, P., additional, Yokoyama, R., additional, and Xu, Z., additional

Published
2022
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40. Extended follow-up and impact of high-risk prognostic factors from the phase 3 RESONATE study in patients with previously treated CLL/SLL

Author

Brown, J R, Hillmen, P, OʼBrien, S, Barrientos, J C, Reddy, N M, Coutre, S E, Tam, C S, Mulligan, S P, Jaeger, U, Barr, P M, Furman, R R, Kipps, T J, Cymbalista, F, Thornton, P, Caligaris-Cappio, F, Delgado, J, Montillo, M, DeVos, S, Moreno, C, Pagel, J M, Munir, T, Burger, J A, Chung, D, Lin, J, Gau, L, Chang, B, Cole, G, Hsu, E, James, D F, and Byrd, J C

Published
2018
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43. PB1878: CROSS-TRIAL ANALYSIS OF FIXED-DURATION IBRUTINIB (I) PLUS VENETOCLAX (V) VS FLUDARABINE (F), CYCLOPHOSPHAMIDE (C), AND RITUXIMAB (R) AS FIRST-LINE TREATMENT FOR CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)

Author

Barrientos, J. C., primary, Barr, P. M., additional, Mato, A. R., additional, Tam, C. S., additional, Ghia, P., additional, Moreno, C., additional, Kay, N. E., additional, Siddiqi, T., additional, Szafer-Glusman, E., additional, Zhou, C., additional, Neumayr, L., additional, Krigsfeld, G., additional, Wierda, W. G., additional, and Shanafelt, T., additional

Published
2022
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44. P1231: ZILOVERTAMAB VEDOTIN (MK-2140) FOR THE TREATMENT OF NON-HODGKIN LYMPHOMA: THE PHASE 1 DOSE ESCALATION AND COHORT EXPANSION WAVELINE-001 STUDY OF AN ANTI-ROR1 ANTIBODY-DRUG CONJUGATE

Author

Wang, M., primary, Mei, M., additional, Barr, P. M., additional, Barrientos, J., additional, de Vos, S., additional, Furman, R., additional, Patel, K., additional, Thompson, P. A., additional, Choi, M., additional, Kallam, A., additional, Zhu, Y., additional, Chakraborty, S., additional, Marinello, P., additional, and Spurgeon, S. E., additional

Published
2022
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48. Updated efficacy including subgroup analyses and safety in the phase 3 RESONATETM trial of ibrutinib versus ofatumumab in previously treated chronic lymphocytic leukaemia/small lymphocytic lymphoma: 35

Author

Dearden, C, Brown, J R, Hillmen, P, OʼBrien, S, Barrientos, J C, Reddy, N M, Coutre, S, Tam, C S, Mulligan, S, Jaeger, U, Barr, P M, Furman, R R, Kipps, T J, Cymbalista, F, Caligaris-Cappio, F, Delgado, J, Montillo, M, DeVos, S, Moreno, C, Pagel, J, Burger, J, Chung, D, Lin, J, Gau, L, Chang, B, James, D, Byrd, J, and Thornton, P

Published
2015

49. Second interim analysis of a phase 3 study of idelalisib plus rituximab (R) for relapsed chronic lymphocytic leukaemia (CLL): efficacy analysis in patient subpopulations with Del(17p) and other adverse prognostic factors: 34

Author

Munir, T, Hillmen, P, Sharman, J, Coutre, S, Furman, R, Cheson, B, Pagel, J, Barrientos, J, Zelenetz, A, Kipps, T, Flinn, I, Ghia, P, Hallek, M, Coiffier, B, OʼBrien, S, Tausch, E, Kreuzer, K, Jiang, W, Lazarov, M, Li, D, Jahn, T, and Stilgenbauer, S

Published
2015

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