465 results on '"Barsyte-Lovejoy, Dalia"'
Search Results
2. A chemical probe to modulate human GID4 Pro/N-degron interactions
3. Interplay between β-propeller subunits WDR26 and muskelin regulates the CTLH E3 ligase supramolecular complex
4. Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity
5. Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing
6. A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity
7. Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations
8. The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition
9. Reference compounds for characterizing cellular injury in high-content cellular morphology assays
10. HiBiT Cellular Thermal Shift Assay (HiBiT CETSA)
11. Measuring Protein–Protein Interactions in Cells using Nanoluciferase Bioluminescence Resonance Energy Transfer (NanoBRET) Assay
12. PRMT inhibition induces a viral mimicry response in triple-negative breast cancer
13. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor
14. Distal extracellular teneurin region (teneurin C-terminal associated peptide; TCAP) possesses independent intracellular calcium regulating actions, in vitro: A potential antagonist of corticotropin-releasing factor (CRF)
15. Chemical biology and pharmacology of histone lysine methylation inhibitors
16. Enzymatic nucleosome acetylation selectively affects activity of histone methyltransferases in vitro
17. PRMT5 regulates ATF4 transcript splicing and oxidative stress response
18. PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade
19. A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization
20. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities
21. Probing CRL4DCAF12 interactions with MAGEA3 and CCT5 di-Glu C-terminal degrons
22. Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening
23. Protein arginine methylation: from enigmatic functions to therapeutic targeting
24. PRMT5 is required for full-lengthHTTexpression by repressing multiple proximal intronic polyadenylation sites
25. A resource to enable chemical biology and drug discovery of WDR Proteins
26. Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex
27. Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors
28. PRMT5 inhibition disrupts splicing and stemness in glioblastoma
29. Characterization of inv(3) cell line OCI-AML-20 with stroma-dependent CD34 expression
30. Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations
31. Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations
32. Chemical Tools for the Gid4 Subunit of the Human E3 Ligase C-terminal to LisH (CTLH) Degradation Complex
33. Recruitment of FBXO22 for Targeted Degradation of NSD2
34. Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3
35. Targeting protein methylation: from chemical tools to precision medicines
36. Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings
37. Probing the DCAF12 interactions with MAGEA3 and CCT5 C-terminal degrons
38. Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6
39. Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response
40. Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response
41. Therapeutic Discovery for Chromatin Complexes: Where Do We Stand?
42. Probing the mechanism of Cbl-b inhibition by a small-molecule inhibitor
43. Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complexElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d3md00633f
44. Discovery of a chemical probe for PRDM9
45. A chemical biology toolbox to study protein methyltransferases and epigenetic signaling
46. Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells
47. Development of HC-258, a Covalent Acrylamide TEAD Inhibitor That Reduces Gene Expression and Cell Migration.
48. Data from The c-Myc Oncogene Directly Induces the H19 Noncoding RNA by Allele-Specific Binding to Potentiate Tumorigenesis
49. Supplementary Figure 1 from Identification of a Novel c-Myc Protein Interactor, JPO2, with Transforming Activity in Medulloblastoma Cells
50. Supplementary Figures 1-5 from CUL7 Is a Novel Antiapoptotic Oncogene
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