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Your search keyword '"Barthels, Derek"' showing total 18 results
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18 results on '"Barthels, Derek"'

3. Kruppel-Like Factor 2 and Matrix Metalloproteinases in the Context of Vasculature

Author

Anderson, Sarah, Barthels, Derek, Das, Hiranmoy, Karamanos, Nikos K., Series Editor, Kletsas, Dimitris, Editorial Board Member, Oh, Eok-Soo, Editorial Board Member, Passi, Alberto, Editorial Board Member, Pihlajaniemi, Taina, Editorial Board Member, Ricard-Blum, Sylvie, Editorial Board Member, Sagi, Irit, Editorial Board Member, Savani, Rashmin, Editorial Board Member, Watanabe, Hideto, Editorial Board Member, Papadimitriou, Evangelia, editor, and Mikelis, Constantinos M., editor

Published
2023
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12. Dental Pulp-Derived Stem Cells Preserve Astrocyte Health During Induced Gliosis by Modulating Mitochondrial Activity and Functions

Author

Barthels, Derek, primary, Prateeksha, Prateeksha, additional, Nozohouri, Saeideh, additional, Villalba, Heidi, additional, Zhang, Yong, additional, Sharma, Sejal, additional, Anderson, Sarah, additional, Howlader, Md Sariful Islam, additional, Nambiar, Adarsh, additional, Abbruscato, Thomas J., additional, and Das, Hiranmoy, additional

Published
2022
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15. Evaluation of Urea-Based Inhibitors of the Dopamine Transporter Using the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis

Author

Ashraf-Uz-Zaman, Md, primary, Ji, Guangchen, additional, Tidwell, Dalton, additional, Yin, Linda, additional, Thakolwiboon, Smathorn, additional, Pan, Jie, additional, Junell, Riley, additional, Griffin, Zach, additional, Shahi, Sadisna, additional, Barthels, Derek, additional, Sajib, Md Sanaullah, additional, Trippier, Paul C., additional, Mikelis, Constantinos M., additional, Das, Hiranmoy, additional, Avila, Mirla, additional, Neugebauer, Volker, additional, and German, Nadezhda A., additional

Published
2022
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18. Generation of Acute Hind Limb Ischemia in NOD/SCID Mice and Treatment with Nanofiber-Expanded CD34 + Hematopoietic Stem Cells.

Author

Barthels D and Das H

Subjects
Animals, Cell Differentiation genetics, Extremities growth & development, Extremities pathology, Fetal Blood transplantation, Hematopoietic Stem Cells cytology, Humans, Ischemia pathology, Mice, Mice, Inbred NOD, Mice, SCID, Hematopoietic Stem Cell Transplantation methods, Ischemia therapy, Nanofibers chemistry, Neovascularization, Physiologic genetics
Abstract

Critical limb ischemia (CLI) is primarily associated with a high risk of major amputation, cardiovascular events, and death. The current therapy involves direct endovascular intervention and is associated with long-term recurrence. However, patients with significant comorbidities are not eligible for this therapy. Hind limb ischemia model via femoral artery excision has commonly been used to determine therapeutic potential and for investigating cellular and molecular mechanisms. This protocol describes the ischemic model development in NOD/SCID mice and the use of human umbilical cord blood-derived and nanofiber scaffold-expanded CD34 + stem cells to investigate the efficacy of regenerative therapy.

Published
2021
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