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2 ABSTRACT Charles University, Faculty of Pharmacy in Hradec Králové Department of: Pharmaceutical Technology Consultant: PharmDr. Petra Svačinová, Ph.D. Student: Eva Bartoňová Title of Thesis: Spray drying of a suspension of the drug in a solution of chitosan During spray drying a liquid solution, suspension, or emulsion is converted to solid particles by means of a hot drying medium. The set drying parameters can affect the properties of the resulting particles. This work deals with the preparation of particles from a suspension of meloxicam in a solution of chitosan and the influence of the drying parameters and the concentration of this solution on the properties of the particles. The concentration of the solution was 0,5 %, 1 %, 1,5 % and 2 %. The inlet temperature was set at 170, 190 and 210 řC. The 2% sample was not dried due to high viscosity and nozzle clogging. The particles were evaluated by optical microscopy, scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and a dissolution test was used to evaluate the drug release from the particles. Two measurements were performed by DSC, the first M1 after drying the particles and the second M2 after 6 months. The resulting particles were spherical and irregular in shape and formed clumps. The particle shape was not affected by...

The thesis maps and compares the success of solving the game activities of the players of the Czech women's national football team. It is a diagnostic of eight games played in the qualifications for the 2019 World Championship. The thesis investigates the success of the selected gaming activities of the Czech team as a whole, and in these activities it compares the success of defensive players, midfielders and offensive players.

The aim of the diploma thesis is an analysis of development in selected states of the Euro-Mediterranean partnership in political, economic and standard of living area. In theoretical part the thesis deals with a description of a mutual relationship between the European Union and states of Mediterranean in the time frame from 1995 to 2015 and the analytical part examines the development of the states towards the goals of the Partnership, which includes the establishment of a common area of peace, stability and shared prosperity. Comparison with the development of member states of the European Union in selected areas is also incorporated.

Esta tesis analiza los efectos del “mainstreaming” del Comercio Justo sobre el banano certificado en Ecuador. Se trata de un país en desarrollo con producción de banano predominantemente a pequeña escala, lo cual permite analizar los temas de investigación. La tesis evalúa la entrada de actores convencionales al modelo que originalmente pretendía formar una alternativa al mercado convencional asimétrico. El estudio de caso cuenta con información de dos asociaciones ecuatorianas de pequeños productores de banano en el Comercio Justo: Asoguabo y Cerro Azul. Según los resultados de investigación, el estudio concluye que el “mainstreaming” es una forma de Comercio Justo necesaria para un producto de corta duración y altos volúmenes, como el banano. No se han encontrado casos de cooptación del modelo por los actores convencionales y las certificaciones pretenden mejorar el bienestar de los pequeños productores bananeros. Sin embargo, se evidencia un impacto más positivo de la presencia de compradores transnacionales en el modelo que de grandes plantaciones de banano. Se recomienda la diversificación del sello de Comercio Justo, así como realizar en el futuro un análisis más profundo de impactos de las grandes plantaciones certificadas.

The aim of the thesis is to evaluate the condition of land degradation and food security in the Sahel region. The thesis is divided into three sections: the theoretical and practical section and the proposal. The first part is dedicated to description of the soil types, the main factors of degradation, which affect the quality of soil, and the means of measuring food security. The second section follows the data from theoretical section and presents the analysis of the soil quality, the proportion of agricultural land from total area of the country, the agricultural production and food security with focus on health condition of the population. The situation is analyzed in the selected countries of the Sahel, specifically Mali and Niger. The proposal describes the changes of state policies in the area of agricultural production, the procedures against land degradation and low level of food security in accordance with sustainable development.

The relations between the United States and its traditional ally, Venezuela, experienced a turn for the worse during the presidency of George W. Bush. The Bush administration reacted to the radical president Hugo Chavez with an increase in funding of the so-called democracy promotion in Venezuela and with a silent support of the unsuccessful coup in 2002. The long history of U.S. interventions in Latin America during the cold war gives ground to the criticism by many authors who see these steps as an attempt to get rid of a democratically elected president just because he is confronting the American vision about a political and economic system desirable for the region. This work focuses on democracy promotion as a tool of the U.S. foreign policy, which is on one hand related to the identity of the United States as a unique historical democratic experiment, but also reacts to a threat posed to the national interests by other states. It deals with the types of threats that Hugo Chavez could have possibly presented, and thus shows to what extent the Bush administration used democracy promotion in a pragmatic way. The analysis of Chavez's actions in oil politics, economic integration and security issues, and its comparison with the trend in democracy promotion shows that the U.S. financing activities...

The thesis deals with a role of developing countries within the WTO and examines whether the developing countries are sufficiently involved in WTO negotiations in order not to play only a marginal role in the multilateral trade system. Thesis contains a historical overview of special and differential treatments for developing countries and the least developed countries. Thesis deals in addition with an issue of the implementation of special and differential treatments and describes the main WTO bodies concerned with implementation. Trade-related technical assistance programs are described in the last part of the thesis. These programs are JITAP, IF and the initiative Aid for Trade.

Práce se zabývá problémy sociální infrastruktury v zemích západní Afriky. Obsahuje socio-ekonomickou charakteristiku zemí patřících do dané oblasti. Dále popisuje současnou situaci ve zdravotnictví a školství v celé oblasti a uvádí příčiny (nedostatek financí, nerozvinutá technická infrastruktura, korupce, vysoký populační růst, nedostatek pitné vody, potravin) a důsledky (nedostatek kvalifikované pracovní síly, špatný zdravotní stav obyvatel) tohoto stavu. V poslední části je porovnáváno školství a zdravotnictví Ghany a Nigeru, nejlepšího a nejzaostalejšího státu regionu.