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1. Evaluation of antioxidant, toxicological and anxiolytic-like effect of ethanolic extracts of Ziziphus cotinifolia Reissek in adult zebrafish (Danio rerio)

Author

de Azevedo, Djane Ventura, Silva, Dimitri Matos, Magalhães, Francisco Ernani A., de Araújo, José Ismael F., de Araujo, Sandra Maria Barbosa, Lopes, Francisco Flavio da Silva, de Moraes, Selene Maia, Batista, Francisco Lucas Alves, Moura, Luiz Francisco Wemmenson Gonçalves, and Guedes, Maria Izabel Florindo

Published
2024
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2. Antibacterial activity and anxiolytic-like effect of Ziziphus joazeiro Mart. leaves in adult zebrafish (Danio rerio)

Author

de Souza, Antônio Barros, Pinheiro, Jacqueline Cosmo Andrade, Soares, Juliete Bezerra, de Araújo, José Ismael Feitosa, de Araújo, Sandra Maria Barbosa, Batista, Francisco Lucas Alves, de Sousa, Kalina Kelma Oliveira, Tintino, Saulo Relison, Araujo, Isaac Moura, Magalhães, Francisco Ernani Alves, Leite, Laura Hévila Inocencio, and de Azevedo, Francisco Roberto

Published
2023
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4. Evaluation of the antifungal activity of α, β, and δ-damascone and inclusion complexes in β-cyclodextrin against Candida spp

Author

de Oliveira, Maria Rayane Correia, de Lima Silva, Maria Gabriely, dos Santos, Antonia Thassya Lucas, Batista, Francisco Lucas Alves, da Costa, Roger Henrique Sousa, Martins, Anita Oliveira Brito Pereira Bezerra, da Cruz, Beatriz Gonçalves, Morais-Braga, Maria Flaviana Bezerra, Coutinho, Henrique Douglas Melo, Magalhães, Francisco Ernani Alves, de Sena Junior, Diniz Maciel, Teixeira, Alexandre Magno Rodrigues, and de Menezes, Irwin Rose Alencar

Published
2022
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6. Orofacial antinociceptive effect of sulphated polysaccharide from the marine algae Hypnea pseudomusciformis in rodents

Author

Souza, Caio Átila Prata Bezerra, de Oliveira, Breytiner Amaro, Santos, Sacha Aubrey Alves Rodrigues, Batista, Francisco Lucas Alves, Andrade, Francisco Regivânio Nascimento, Neto, Eugênio Januário Ramos, de Melo Júnior, José de Maria Albuquerque, Silva Mendes, Francisco Rogenio da, Barroso, Lana Karine Vasconcelos, Canuto, Kirley Marques, Magalhães, Francisco Ernani Alves, e Silva, Angelo Roncalli Alves, Farias, Wladimir Ronald Lobo, and Campos, Adriana Rolim

Published
2019
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7. Antiedematogenic and Analgesic Activities of Abietic Acid in Mice

Author

de Lima Silva, Maria Gabriely, primary, Santos da Silva, Lucas Yure, additional, Torres Pessoa, Renata, additional, de Oliveira, Maria Rayane Correia, additional, Batista, Francisco Lucas Alves, additional, Alcântara, Isabel Sousa, additional, Bezerra Martins, Anita Oliveira Brito Pereira, additional, Ribeiro‐Filho, Jaime, additional, Coutinho, Henrique Douglas Melo, additional, and de Menezes, Irwin Rose Alencar, additional

Published
2023
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9. UPLC-MS-ESI-QTOF Analysis and Antifungal Activity of Aqueous Extracts of Spondias tuberosa

Author

Santos, Antonia Thassya Lucas dos, primary, Carneiro, Joara Nályda Pereira, additional, da Cruz, Rafael Pereira, additional, Sales, Débora Lima, additional, Andrade-Pinheiro, Jacqueline Cosmo, additional, de Freitas, Maria Audilene, additional, Kerntopf, Marta Regina, additional, Delmondes, Gyllyandeson de Araújo, additional, Ribeiro, Paulo Riceli Vasconcelos, additional, de Brito, Edy Sousa, additional, Batista, Francisco Lucas Alves, additional, Magalhães, Francisco Ernani Alves, additional, Pita Neto, Ivo C., additional, Morais-Braga, Maria Flaviana Bezerra, additional, Kowalski, Radosław, additional, Kowalska, Grazyna, additional, Szopa, Aleksandra, additional, Baj, Tomasz, additional, and Coutinho, Henrique Douglas Melo, additional

Published
2022
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10. Mechanisms of Actions Involved in The Antinociceptive Effect of Estragole and its β-Cyclodextrin Inclusion Complex in Animal Models

Author

da Costa, Roger Henrique Sousa, primary, Martins, Anita Oliveira Brito Pereira Bezerra, additional, Pessoa, Renata Torres, additional, Alshehri, Saad Ali, additional, Wahab, Shadma, additional, Ahmad, Md Faruque, additional, Suliman, Muath, additional, da Silva, Lucas Yure Santos, additional, Alcântara, Isabel Sousa, additional, Ramos, Andreza Guedes Barbosa, additional, Oliveira, Maria Rayane Correia de, additional, Batista, Francisco Lucas Alves, additional, Delmondes, Gyllyandeson de Araújo, additional, de Farias, Pablo Antonio Maia, additional, Rocha, Janaína Esmeraldo, additional, Coutinho, Henrique Douglas Melo, additional, Raposo, António, additional, Carrascosa, Conrado, additional, Jaber, José Raduan, additional, and de Menezes, Irwin Rose Alencar, additional

Published
2022
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11. Evaluation of the ethanolic extract of Myconia albicas (Old Cinnamon) in the alternative model of anxiety in zebrafish

Author

Castro, Fernanda Mota de, primary, Alexandre, Aimê Veras, additional, Batista, Francisco Lucas Alves, additional, Santos, Sacha Aubrey Alves Rodrigues, additional, Mendes, Francisco Rogênio da Silva, additional, Monteiro Moreira, Ana Cristina de Oliveira, additional, Magalhães, Francisco Ernani Alves, additional, Honório Júnior, José Eduardo Ribeiro, additional, and Camposa, Adriana Rolim, additional

Published
2022
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12. UPLC-MS-ESI-QTOF Analysis and Antifungal Activity of Aqueous Extracts of Spondias tuberosa.

Author

Santos, Antonia Thassya Lucas dos, Carneiro, Joara Nályda Pereira, da Cruz, Rafael Pereira, Sales, Débora Lima, Andrade-Pinheiro, Jacqueline Cosmo, de Freitas, Maria Audilene, Kerntopf, Marta Regina, Delmondes, Gyllyandeson de Araújo, Ribeiro, Paulo Riceli Vasconcelos, de Brito, Edy Sousa, Batista, Francisco Lucas Alves, Magalhães, Francisco Ernani Alves, Pita Neto, Ivo C., Morais-Braga, Maria Flaviana Bezerra, Kowalski, Radosław, Kowalska, Grazyna, Szopa, Aleksandra, Baj, Tomasz, and Coutinho, Henrique Douglas Melo

Subjects
EXTRACTS, PATHOGENIC fungi, CANDIDA albicans, LIQUID chromatography, ANALYTICAL chemistry
Abstract

This study aimed to identify the chemical composition of the Spondias tuberosa aqueous leaf and root extracts (EALST and EARST) and to evaluate their effect, comparatively, against opportunistic pathogenic fungi. Ultra-Performance Liquid Chromatography Coupled to a Quadrupole/Time of Flight System (UPLC-MS-ESI-QTOF) was employed for chemical analysis. Candida albicans and C. tropicalis standard strains and clinical isolates were used (CA INCQS 40006, CT INCQS 40042, CA URM 5974, and CT URM 4262). The 50% Inhibitory Concentration for the fungal population (IC50) was determined for both the intrinsic action of the extracts and the extract/fluconazole (FCZ) associations. The determination of the Minimum Fungicidal Concentration (MFC) and the verification of effects over fungal morphological transitions were performed by subculture in Petri dishes and humid chambers, respectively, both based on micro-dilution. UPLC-MS-ESI-QTOF analysis revealed the presence of phenolic and flavonoid compounds. The association of the extracts with fluconazole, resulted in IC50 values from 2.62 µg/mL to 308.96 µg/mL. The MFC of the extracts was ≥16,384 µg/mL for all tested strains, while fluconazole obtained an MFC of 8192 µg/mL against C. albicans strains. A reduction in MFC against CA URM 5974 (EALST: 2048 µg/mL and EARST: 1024 µg/mL) occurred in the extract/fluconazole association. [ABSTRACT FROM AUTHOR]

Published
2023
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13. Chemical Constituents and Biological Activities of Croton heliotropiifolius Kunth

Author

Fernandes, Priscilla Augusta de Sousa, primary, Silva, Josefa Carolaine Pereira da, additional, Lima Sales, Débora, additional, Ribeiro, Paulo Riceli Vasconcelos, additional, Sousa de Brito, Edy, additional, Kerntopf, Marta Regina, additional, Delmondes, Gyllyandeson de Araújo, additional, Andrade Pinheiro, Jacqueline Cosmo, additional, Salazar, Gerson Javier Torres, additional, Batista, Francisco Lucas Alves, additional, Alves Magalhães, Francisco Ernani, additional, Gomez, Maria Celeste Vega, additional, Rolón, Míriam, additional, Coronel, Cathia, additional, Ribeiro-Filho, Jaime, additional, Almeida-Bezerra, José Weverton, additional, Siyadatpanah, Abolghasem, additional, Nissapatorn, Veeranoot, additional, Pereira, Maria de Lourdes, additional, Coutinho, Henrique Douglas Melo, additional, and Morais-Braga, Maria Flaviana Bezerra, additional

Published
2021
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14. Antibacterial and antioxidant potential of Spondias tuberosa Arruda (Anacardiaceae) extracts

Author

Santos, Antonia Thassya Lucas dos, primary, Carneiro, Joara Nályda Pereira, additional, Andrade-Pinheiro, Jacqueline Cosmo, additional, Araújo-Neto, José Bezerra de, additional, Sales, Débora Lima, additional, Freitas, Maria Audilene de, additional, Almeida-Bezerra, José Weverton, additional, Batista, Francisco Lucas Alves, additional, Magalhães, Francisco Ernani Alves, additional, Pereira, Cícera Cryslany Soares Sales, additional, Luciano-Torres, Maria de Lara Alves, additional, Lima, Elvis Estilak, additional, Coutinho, Henrique Douglas Melo, additional, and Morais-Braga, Maria Flaviana Bezerra, additional

Published
2020
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15. Graviola Fruit Bar Added Acerola By-Product Extract Protects Against Inflammation and Nociception in Adult Zebrafish (Danio rerio)

Author

Silva, Larissa Morais Ribeiro da, primary, Lima, Jorgiane da Silva Severino, additional, Magalhães, Franscisco Ernani Alves, additional, Campos, Adriana Rolim, additional, Araújo, José Ismael Feitosa de, additional, Batista, Francisco Lucas Alves, additional, Araújo, Sandra Maria Barbosa de, additional, Sousa, Paulo Henrique Machado de, additional, Lima, Glauber Cruz, additional, Holanda, Dayse Karine Rodrigues, additional, Rolim, Rhaul Cândido, additional, Figueiredo, Raimundo Wilane de, additional, Figueiredo, Evânia Altina Teixeira de, additional, Duarte, Antoniella Souza Gomes, additional, and Ricardo, Nágila Maria Pontes Silva, additional

Published
2020
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16. Adult Zebrafish (Danio rerio) As a Model for the Study of Corneal Antinociceptive Compounds

Author

Magalhães, Francisco Ernani Alves, primary, Batista, Francisco Lucas Alves, additional, Lima, Luiza Michelly Gonçalves, additional, Abrante, Izamar de Araújo, additional, Batista, Francisca Leidivânia Alves, additional, Abrante, Izabel de Araújo, additional, de Araújo, José Ismael Feitosa, additional, Santos, Sacha Aubrey Alves Rodrigues, additional, de Oliveira, Breytiner Amaro, additional, Raposo, Ramon da Silva, additional, and Campos, Adriana Rolim, additional

Published
2018
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17. Orofacial antinociceptive effect of sulphated polysaccharide from the marine algae Hypnea pseudomusciformis in rodents

Author

Souza, Caio Átila Prata Bezerra, primary, de Oliveira, Breytiner Amaro, additional, Santos, Sacha Aubrey Alves Rodrigues, additional, Batista, Francisco Lucas Alves, additional, Andrade, Francisco Regivânio Nascimento, additional, Neto, Eugênio Januário Ramos, additional, de Melo Júnior, José de Maria Albuquerque, additional, Silva Mendes, Francisco Rogenio da, additional, Barroso, Lana Karine Vasconcelos, additional, Canuto, Kirley Marques, additional, Magalhães, Francisco Ernani Alves, additional, e Silva, Angelo Roncalli Alves, additional, Farias, Wladimir Ronald Lobo, additional, and Campos, Adriana Rolim, additional

Published
2018
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18. Adult Zebrafish (Danio rerio): An Alternative Behavioral Model of Formalin-Induced Nociception

Author

Magalhães, Francisco Ernani Alves, primary, de Sousa, Caio Átila Prata Bezerra, additional, Santos, Sacha Aubrey Alves Rodrigues, additional, Menezes, Renata Barbosa, additional, Batista, Francisco Lucas Alves, additional, Abreu, Ângela Oliveira, additional, de Oliveira, Messias Vital, additional, Moura, Luiz Francisco Wemmenson Gonçalves, additional, Raposo, Ramon da Silva, additional, and Campos, Adriana Rolim, additional

Published
2017
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19. POTENCIAL ANTIBACTERIANO DO COGUMELO COMESTÍVEL Pleurotus ostreatus FRENTE À Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853 E Escherichia coli ATCC 25922

Author

Cândido Sobrinho, Silvio Alencar, primary, Torres, Marcia Rocha, additional, Silva Filho, Eduardo Augusto Torres, additional, Vasconcelos, Fábio Roger, additional, Guedes, Maria Izabel Florindo, additional, Lima, Daniele Rodrigues de, additional, Franca, Maria Gleiziane Araújo, additional, Moura, Luiz Francisco Wemmenson Gonçalves, additional, Oliveira, Messias Vidal de, additional, Batista, Francisco Lucas Alves, additional, and Magalhães, Francisco Ernani Alves, additional

Published
2017
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20. Potencial antifúngico de quitosanases extracelulares de Fusarium solani FA14 contra os fitopatógenos Aspergillus niger, Colletotrichum gloeosporioides e Lasiodiplodia theobromae

Author

Bezerra Neto, Samuel Alves, primary, Da Costa, Lorena Nogueira Frota, additional, Magalhães, Erlândia Alves, additional, Batista, Francisco Lucas Alves, additional, Moura, Luiz Francisco Wemmenson Gonçalves, additional, Franca, Maria Gleiziane Araújo, additional, De Paiva, Cristiane Félix, additional, De Lima, Daniele Rodrigues, additional, De Oliveira, Messias Vital, additional, Guedes, Maria Izabel Florindo, additional, Freire, Francisco das Chagas de Oliveira, additional, and Magalhães, Francisco Ernani Alves, additional

Published
2016
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21. Antibacterial activity and anxiolytic-like effect of Ziziphus joazeiroMart. leaves in adult zebrafish (Danio rerio)

Author

de Souza, Antônio Barros, Pinheiro, Jacqueline Cosmo Andrade, Soares, Juliete Bezerra, de Araújo, José Ismael Feitosa, de Araújo, Sandra Maria Barbosa, Batista, Francisco Lucas Alves, de Sousa, Kalina Kelma Oliveira, Tintino, Saulo Relison, Araujo, Isaac Moura, Magalhães, Francisco Ernani Alves, Leite, Laura Hévila Inocencio, and de Azevedo, Francisco Roberto

Abstract

•The extract of Z. joazeiroMart. leaves (EEFZJ) showed the presence of flobabenic tannins, leucoanthocyanidins, flavonois, flavonones.•There was no clinically relevant antibacterial activity, but the extract showed synergistic.•This extract was non toxic and evidenced sedative effect in adult zebrafish.•That Z. joazeirohas potential as an alternative plant-derived of phytomedicines against resistant bacterial infections and anxiolytic therapy.

Published
2023
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