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2. Effect of COVID-19-related lockdown on ophthalmic practice in Italy: A report from 39 institutional centers

Author

Dell'Omo, Roberto, Filippelli, M., Virgili, Gianni, Bandello, F., Querques, G., Lanzetta, P., Avitabile, T., Viola, F., Reibaldi, M., Semeraro, F., Quaranta, L., Rizzo, Stanislao, Midena, E., Campagna, G., Costagliola, C., Marolo, P., Traverso, C. E., Iester, M., Cutolo, C. A., Azzolini, C., Donati, S., Premi, E., Nucci, P., Vujosevic, S., Staurenghi, G., Bottoni, F., Romano, Federica, Grosso, D., Borrelli, E., Sacconi, R., Milella, P., Ganci, S., Romano, M. R., Ricciardelli, G., Allegrini, D., Casaluci, M., Romano, D., Marchini, G., Chemello, F., Amantea, Carlotta, Frisina, R., Pilotto, E., Parrozzani, R., Veritti, D., Sarao, V., Daniele, T., Busin, M., Parmeggiani, F., De Nadai, K., Furiosi, L., Mastropasqua, R., Battaglia, B., Gironi, Marco, Gandolfi, S., Luciani, E., Mora, P., Schiavi, C., Bertaccini, Paolo Antonio, Finzi, A., Roda, M., Cagini, C., Lupidi, M., Giansanti, F., Bacherini, Daniela, Tosi, G., De Benedetto, E., Nardi, M., Figus, M., Posarelli, C., Mariotti, Cesare, Pirani, V., Nicolai, Massimo, Bonini, S., Coassin, M., Di Zazzo, A., Savastano, Maria Cristina, Savastano, Alfonso, Gambini, Gloria, Vico, U. D., Spadea, L., Iannaccone, A., Nucci, C., Ricci, F., Aiello, F., Afflitto, G. G., Mastropasqua, L., D'Onofio, G., Evangelista, F., Brescia, L., Napolitano, P., Polisena, P., Gianfrancesco, N., Trivisonno, D., Petti, F., Simonelli, F., Rossi, S., Tartaglione, A., Rosa, N., Bernardo, M. D., Iaculli, C., Valeria Bux, A., Maggiore, Giuseppe, Boscia, F., Sborgia, G., Grassi, M. O., Scorcia, V., Giannaccare, G., Parisi, Giuseppe, Cillino, S., Alaimo, F., Aragona, P., Meduri, A., Pinna, A., Sollazzo, A., Peiretti, E., Siotto, E., dell'Omo R., Virgili G., Rizzo S. (ORCID:0000-0001-6302-063X), Romano F., Amantea C., Gironi M., Bertaccini P., Bacherini D., Mariotti C., Nicolai M., Savastano M. (ORCID:0000-0003-1397-4333), Savastano A., Gambini G., Maggiore G., Parisi G., Dell'Omo, Roberto, Filippelli, M., Virgili, Gianni, Bandello, F., Querques, G., Lanzetta, P., Avitabile, T., Viola, F., Reibaldi, M., Semeraro, F., Quaranta, L., Rizzo, Stanislao, Midena, E., Campagna, G., Costagliola, C., Marolo, P., Traverso, C. E., Iester, M., Cutolo, C. A., Azzolini, C., Donati, S., Premi, E., Nucci, P., Vujosevic, S., Staurenghi, G., Bottoni, F., Romano, Federica, Grosso, D., Borrelli, E., Sacconi, R., Milella, P., Ganci, S., Romano, M. R., Ricciardelli, G., Allegrini, D., Casaluci, M., Romano, D., Marchini, G., Chemello, F., Amantea, Carlotta, Frisina, R., Pilotto, E., Parrozzani, R., Veritti, D., Sarao, V., Daniele, T., Busin, M., Parmeggiani, F., De Nadai, K., Furiosi, L., Mastropasqua, R., Battaglia, B., Gironi, Marco, Gandolfi, S., Luciani, E., Mora, P., Schiavi, C., Bertaccini, Paolo Antonio, Finzi, A., Roda, M., Cagini, C., Lupidi, M., Giansanti, F., Bacherini, Daniela, Tosi, G., De Benedetto, E., Nardi, M., Figus, M., Posarelli, C., Mariotti, Cesare, Pirani, V., Nicolai, Massimo, Bonini, S., Coassin, M., Di Zazzo, A., Savastano, Maria Cristina, Savastano, Alfonso, Gambini, Gloria, Vico, U. D., Spadea, L., Iannaccone, A., Nucci, C., Ricci, F., Aiello, F., Afflitto, G. G., Mastropasqua, L., D'Onofio, G., Evangelista, F., Brescia, L., Napolitano, P., Polisena, P., Gianfrancesco, N., Trivisonno, D., Petti, F., Simonelli, F., Rossi, S., Tartaglione, A., Rosa, N., Bernardo, M. D., Iaculli, C., Valeria Bux, A., Maggiore, Giuseppe, Boscia, F., Sborgia, G., Grassi, M. O., Scorcia, V., Giannaccare, G., Parisi, Giuseppe, Cillino, S., Alaimo, F., Aragona, P., Meduri, A., Pinna, A., Sollazzo, A., Peiretti, E., Siotto, E., dell'Omo R., Virgili G., Rizzo S. (ORCID:0000-0001-6302-063X), Romano F., Amantea C., Gironi M., Bertaccini P., Bacherini D., Mariotti C., Nicolai M., Savastano M. (ORCID:0000-0003-1397-4333), Savastano A., Gambini G., Maggiore G., and Parisi G.

Abstract

Background/objectives: To compare the number of eye surgical procedures performed in Italy in the 2 months following the beginning of lockdown (study period) because of COVID-19 epidemic with those performed in the two earlier months of the same year (intra-year control) and in the period of 2019 corresponding to the lockdown (inter-year control). Methods: Retrospective analysis of surgical procedures carried out at 39 Academic hospitals. A distinction was made between elective and urgent procedures. Intravitreal injections were also considered. Percentages for all surgical procedures and incidence rate ratios (IRR) for rhegmatogenous retinal detachment (RRD) events were calculated. A p value <0.05 was considered significant. Results: A total of 20,886 versus 55,259 and 56,640 patients underwent surgery during the lockdown versus intra-and inter-year control periods, respectively. During the lockdown, only 70% of patients for whom an operation/intravitreal injection was recommended, finally underwent surgery; the remaining patients did not attend because afraid of getting infected at the hospital (23%), taking public transportation (6.5%), or unavailable swabs (0.5%). Elective surgeries were reduced by 96.2% and 96.4%, urgent surgeries by 49.7% and 50.2%, and intravitreal injections by 48.5% and 48.6% in the lockdown period in comparison to intra-year and inter-year control periods, respectively. IRRs for RRDs during lockdown dropped significantly in comparison with intra- and inter-year control periods (CI: 0.65–0.80 and 0.61–0.75, respectively, p < 0.001 for both). Conclusion: This study provides a quantitative analysis of the reduction of eye surgical procedures performed in Italy because of the COVID-19 epidemic.

Published
2022

9. Cigarette Smoking and Cardiovascular Risk in Young Women with Polycystic Ovary Syndrome

Author

ELENA MOROTTI, Battaglia, B., Fabbri, R., Paradisi, R., Venturoli, S., Battaglia, C., Morotti E, Battaglia B, Fabbri R, Paradisi R, Venturoli S, and Battaglia C

Subjects
lcsh:R5-920, Gynecology and Female Infertility, smoke, Epidemiology, ultrasound, pcos, Original Article, lcsh:Medicine (General), doppler
Abstract

Background: To verify if in lean polycystic ovary syndrome (PCOS) patients, the smok- ing habitude might increase the risk of cardiovascular (CV) disease. Materials and Methods: In this prospective observational study, eighty-one women were divided into the following three groups: group I with 27 non-smokers, group II with 26 light-smokers (1-10 cigarettes/day), and group III with 28 heavy smokers (>10 cigarettes/ day). They were submitted to fasting blood sampling; blood measurement of nitrites/ni- trates (NO2-/ NO3), biochemical and hormonal parameters; ovarian ultrasonographic (US) analysis; doppler evaluation of uterine and ophthalmic arteries; brachial artery flow-medi- ated vasodilatation; 24-hour ambulatory blood pressure monitoring; and oral glucose toler- ance test (OGTT). Results: Doppler analysis revealed higher uterine and ophthalmic arteries pulsatility in- dex (PI) and ophthalmic artery back pressure in group III compared with group I. The brachial artery diameter and PI, at baseline, was similar among all groups. After the re- active hyperemia, a more intense vasodilatation was observed in group I in comparison with group III. The 24-hour blood pressure demonstrated that, in group III patients, the 24-hour, day- and night-time diastolic blood pressure (DBP), was higher in comparison with non-smokers. The atherogenic index of plasma (AIP) was higher in heavy smokers than in non-smokers. The leukocytes and homocysteine (HCY) values were increased in group III. The NO2-/ NO3- plasma levels were reduced in heavy smokers in compari- son with non-smokers. The insulin, glucose and C-peptide plasma values were higher in group III than in other groups. In heavy smokers, the estimates of insulin sensitivity (ISI) and pancreatic β-cell function (HOMA-B) were higher compared to the other groups. Conclusion: Smoking habitude in lean PCOS patients may increase the soft markers of CV risk.

Published
2014

11. Body Mass Index, Stunkard Figure Rating Scale, and Sexuality in Young Italian Women: A Pilot Study

Author

Morotti E, Battaglia B, Zampieri M, MOROTTI, ELENA, PARADISI, ROBERTO, PERSICO, NICOLA, VENTUROLI, STEFANO, BATTAGLIA, CESARE, Morotti E, Battaglia B, Paradisi R, Persico N, Zampieri M, Venturoli S, Battaglia C, DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE, Facolta' di MEDICINA e CHIRURGIA, Da definire, and AREA MIN. 06 - Scienze mediche

Subjects
Adult, medicine.medical_specialty, obesity, body imaging, Cross-sectional study, Urology, Endocrinology, Diabetes and Metabolism, Figure rating scale, Stunkard Figure Rating Scale, Pilot Projects, female sexual behavior, Overweight, clitori, Clitoris, Body Mass Index, Ophthalmic Artery, BMI, Endocrinology, Vascular Stiffness, Weight loss, Surveys and Questionnaires, medicine, Body Image, Humans, Ultrasonography, Doppler, Color, Gynecology, Obstetrics, Body Weight, clitoris, medicine.disease, Obesity, Psychiatry and Mental health, Sexual Dysfunction, Physiological, Sexual dysfunction, Cross-Sectional Studies, Reproductive Medicine, Italy, Pulsatile Flow, Female, medicine.symptom, Psychology, Sexual function, Body mass index, Sexuality
Abstract

Introduction. Increased body mass index is associated with a higher prevalence of metabolic diseases, depression, and sexual dysfunction. In obese patients, the perception of an altered body image may influence health and psycho- logically related behaviors. Furthermore, there is a significant positive relationship between sexual function, sexual satisfaction, and all body image variables. Aim. To evaluate the relationship between body weight, perceived body image, and sexual behavior. Methods. Ninety women underwent ultrasonographic clitoral volume measurement and color Doppler evaluation of the clitoral and ophthalmic arteries. The subjects filled the McCoy Female Sexuality Questionnaire (MFSQ), the Stunkard Figure Rating Scale (FRS), and the Beck's Depression Inventory (BDI) questionnaire. Main Outcome Measures. Clitoral volume, clitoral and ophthalmic artery pulsatility index (PI), MFSQ, FRS, and BDI. Results. The women were distributed into three groups: lean (N = 47); overweight (N = 22); and obese (N = 21). The ophthalmic artery showed lower PI in lean (1.72 0.39) than in overweight (1.99 0.30) and obese women (2.08 0.19). The obese subjects presented the worst clitoral vascularization. The MFSQ for sexuality was higher in lean (45.8 11.8) than in overweight (36.4 15.0) and obese (36.1 10.8) women. The frequency of intercourse per week was higher in lean (2.2 1.4) than in overweight (1.3 0.7) and obese (1.2 0.4) women. The percentage of anorgasmic women was higher in obese (23%) than in lean subjects (6%). The FRS evidenced that the lean subjects represented themselves with a mean value (3.5 1.0) lower than overweight (4.8 0.7) and obese women (5.9 0.6). The silhouette that represented their own ideal was significantly higher in obese (4.0 0.4) than in overweight (3.3 0.5) and lean (2.9 0.7) subjects. The mean BDI was significantly higher in obese (15.8 5.4) than in lean (8.4 6.8) women. Conclusions. Lifestyle modifications such as weight loss may be mandatory in obese subjects because obesity might impair the quality of sexual life by inducing genital and general vascular stiffness and body image distortion. Morotti E, Battaglia B, Paradisi R, Persico N, Zampieri M, Venturoli S, and Battaglia C. Body mass index, Stunkard Figure Rating Scale, and sexuality in young Italian women: A pilot study. J Sex Med 2013;10:1034-1043.

Published
2013

23. GENETIC DIFFERENTIATION IN THE GENUS ACARTIA FROM THE LAGOON OF VENICE

Author

Cervelli, M, Battaglia, B, Bisol, R, Scaramuzza, A, Meneghetti, F, Observatoire océanologique de Banyuls (OOB), and Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
1995

31. Human impact on an oligotrophic lake in the Larsemann Hills

Author

Battaglia, B., Valencia, J., Walton, D.W.H., Ellis-Evans, J. Cynan, Laybourn-Parry, J., Bayliss, P.R., Perriss, S.T., Battaglia, B., Valencia, J., Walton, D.W.H., Ellis-Evans, J. Cynan, Laybourn-Parry, J., Bayliss, P.R., and Perriss, S.T.

Published
1997

38. Table of contents.

Author

Battaglia, B., Rice, D., Phuong Le, Gogoi, B., Hoshizaki, G., Purchine, M., Davies, R., Wright, W., Lutz, D., Gao, M., Moline, D., Elliot, A., Son Tran, and Neeley, R.

Published
2008

49. Molecular evolution at subzero temperatures: mitochondrial and nuclear phylogenies of fishes from Antarctica (suborder Notothenioidei), and the evolution of antifreeze glycopeptides.

Author

Bargelloni, L, Ritchie, P A, Patarnello, T, Battaglia, B, Lambert, D M, and Meyer, A

Abstract

Most fishes of the perciform suborder Notothenioidei are endemic to the subzero marine waters of Antarctica. A number of remarkable physiological attributes allow them to inhabit this extreme environment; for example, the blood of almost all notothenioid species contains antifreeze glycopeptides. To establish a molecular phylogenetic hypothesis for these fishes, DNA sequences from two mitochondrial genes, portions of the 12S and 16S ribosomal genes (928 base pairs [bp]), were determined for 18 species. These belong to 15 genera in five families of the suborder. The DNA data suggest that two of these families are unnatural groups and consequently that the classification and phylogeny of this suborder is in need of revision. In terms of DNA variation, the Bovichtidae are a distantly related sister group to the other families of the suborder that includes the icefishes, the only vertebrates without hemoglobin. The fishes of the suborder (except the Bovichtidae) seem to have speciated rapidly, forming an adaptive radiation in the Antarctic waters. A phylogenetic analysis of published hemoglobin amino acid sequences for other notothenioid fishes supports these results from mtDNA. On the basis of molecular phylogeny, the evolution of antifreeze glycopeptides was studied. The age of the radiation of notothenioid fishes had been estimated to be at least 38 Mya. However, the level of mtDNA variation detected in notothenioid fishes appears to be too low to agree with this date of origin and might instead suggest a younger age (10-15 Mya). Alternatively, the low level of detected mtDNA variation would agree with the traditional old-age estimate if an extremely slow rate of mtDNA evolution is postulated for this group. This slow-rate hypothesis, if true, could be explained by decreased metabolic rates slowing down the tempo of molecular evolution.

Published
1994
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