110,348 results on '"Baum, A"'
Search Results
2. The JWST View of Cygnus A: Jet-Driven Coronal Outflow with a Twist
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Ogle, Patrick M., Sebastian, B., Aravindan, A., McDonald, M., Canalizo, G., Ashby, M. L. N., Azadi, M., Antonucci, R., Barthel, P., Baum, S., Birkinshaw, M., Carilli, C., Chiaberge, M., Duggal, C., Gebhardt, K., Hyman, S., Kuraszkiewicz, J., Lopez-Rodriguez, E., Medling, A. M., Miley, G., Omoruyi, O., O'Dea, C., Perley, D., Perley, R. A., Perlman, E., Reynaldi, V., Singha, M., Sparks, W., Tremblay, G., Wilkes, B., Willner, S. P., and Worrall, D. M.
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Astrophysics - Astrophysics of Galaxies - Abstract
We present first results from James Webb Space Telescope (JWST) Near-Infrared Spectrograph (NIRSpec), Mid-Infrared Instrument (MIRI), and Keck Cosmic Webb Imager (KCWI) integral field spectroscopy of the powerful but highly obscured host-galaxy of the jetted radio source Cygnus A. We detect 169 infrared emission lines at 1.7--27 micron and explore the kinematics and physical properties of the extended narrow-line region (NLR) in unprecedented detail. The density-stratified NLR appears to be shaped by the initial blow-out and ongoing interaction of the radio jet with the interstellar medium, creating a multi-phase bicone with a layered structure composed of molecular and ionized gas. The NLR spectrum, with strong coronal emission at kpc-scale, is well-modeled by AGN photoionization. We find evidence that the NLR is rotating around the radio axis, perhaps mediated by magnetic fields and driven by angular momentum transfer from the radio jet. The overall velocity field of the NLR is well described by 250 km/s outflow along biconical spiral flow lines, combining both rotation and outflow signatures. There is particularly bright [Fe II] 1.644 micron emission from a dense, high-velocity dispersion, photoionized clump of clouds found near the projected radio axis. Outflows of 600--2000 km/s are found in bullets and streamers of ionized gas that may be ablated by the radio jet from these clouds, driving a local outflow rate of 40 Msun/yr., Comment: Submitted to Astrophysical Journal
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- 2025
3. Jump Point Search Pathfinding in 4-connected Grids
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Baum, Johannes
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Computer Science - Robotics - Abstract
This work introduces JPS4, a novel pathfinding algorithm for 4-connected grid maps. JPS4 builds upon the Jump Point Search (JPS8) algorithm, originally designed for 8-connected environments. To achieve efficient pathfinding on 4-connected grids, JPS4 employs a canonical ordering and a successor function that enable online graph pruning. This reduces the search space by minimizing unnecessary node expansions. The core concept of JPS4 as well as JPS8 lies in the utilization of jump points. Strategically placed at obstacle corners, jump points prevent the search from overlooking crucial sections of the state space. They essentially reinitialize the canonical ordering, allowing exploration beyond obstacles. This mechanism ensures JPS4 finds optimal paths even in complex environments. The paper further explores the optimality of JPS4 and compares its performance against the established A* algorithm on various grid maps. Benchmarking results demonstrate that JPS4 significantly outperforms A* in scenarios with high obstacle density. However, A* remains more efficient on open maps. Overall, JPS4 presents itself as a promising alternative to A* for pathfinding on 4-connected grids, particularly applicable in video game development.
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- 2025
4. Magnetic Field Structures In and Around Seyfert Galaxy Outflows
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Ghosh, Salmoli, Kharb, P., Sebastian, B., Gallimore, J., Pasetto, A., O'Dea, C. P., Heckman, T., and Baum, S. A.
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Astrophysics - Astrophysics of Galaxies - Abstract
We present radio polarimetric images of 12 Seyfert and Low-Ionization Nuclear Emission-line Region (LINER) galaxies belonging to the Centre for Astrophysics (CfA)+12 micron sample exhibiting kiloparsec-scale radio outflows (KSRs). These observations have been carried out at 10 GHz with Karl G. Jansky Very Large Array (VLA) in D-array and at 1.4 GHz with the BnA$\rightarrow$A array configurations. We find signatures of organized magnetic (B-) field structures in the cores, jets and lobes of these galaxies. The linear polarization fraction varies from a few per cent in the cores to $47\pm18$ per cent in the lobes. The inferred B-fields are toroidal in the cores of several sources making them consistent with the presence of either a sheath-like or a wind-like component surrounding the jet. The in-band spectral index images typically show the presence of flat/inverted spectrum cores and steep spectrum lobes. Radio cores with flatter spectra are found to have lower Eddington ratios while the steeper ones have higher. A strong correlation is observed between the Seyfert/LINER radio outflow properties and the mass of the supermassive black holes (SMBHs); correlations with Eddington ratios are weaker. We find signatures of jet-medium interaction and both positive and negative AGN feedback in these sources. Overall, our study indicates that radio-quiet (RQ) AGN with KSRs possess radio outflows driven by magnetic fields anchored to their black holes - accretion disks, which significantly impact their environments., Comment: 36 pages, 20 figures, 6 tables. Accepted for publication in The Astrophysical Journal
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- 2025
5. VLA+VLBA to ngVLA Transition Option Concepts
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Corsi, Alessandra, Lazio, Joseph W., Baum, Stefi, Giacintucci, Simona, Heald, George, Henning, Patricia, Heywood, Ian, Iono, Daisuke, Johnson, Megan, Lam, Michael T., Leroy, Adam, Loinard, Laurent, Looney, Leslie, Matthews, Lynn, Molter, Ned, Murphy, Eric, Schinnerer, Eva, Tetarenko, Alex, Umana, Grazia, and van der Horst, Alexander
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Astrophysics - Instrumentation and Methods for Astrophysics ,General Relativity and Quantum Cosmology - Abstract
The next-generation Very Large Array (ngVLA) is intended to be the premier centimeter-wavelength facility for astronomy and astrophysics, building on the substantial scientific legacies of the Karl G. Jansky Very Large Array (VLA) and the Very Long Baseline Array (VLBA). The ngVLA would open a new window on the Universe through ultra-sensitive imaging of thermal line and continuum emission to milliarcsecond resolution, while delivering unprecedented broad-band continuum imaging and polarimetry of non-thermal emission. The ngVLA would provide a critical electromagnetic complement to a suite of particle detectors and gravitational-wave observatories, as well as space- and ground-based telescopes operating from infrared to gamma-ray wavelengths, hence enabling multi-messenger and multi-band astronomy and astrophysics. Current construction plans call for the ngVLA to leverage some of the physical infrastructure of both the VLA and the VLBA, potentially drawing on overlapping personnel and information infrastructure. Multiple options can be envisioned for a VLA+VLBA to ngVLA transition. In order to assess risks and benefits of possible transition plans, the ngVLA project established the VLA+VLBA to ngVLA Transition Advisory Group (TAG). The primary deliverable from the TAG is a ``VLA+VLBA to ngVLA Transition Option Concepts'' report (this report) that includes a prioritized list of transition options., Comment: This report reflects an initial set of recommendations by the Transition Advisory Group for the ngVLA Project and is distributed for the purposes of obtaining community comment. Modification of this report in response to community comment is expected. Please submit your feedback at ngvla-transition-feedback@listmgr.nrao.edu
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- 2025
6. A Living Stipend for Students with Financial Need: Supplementing Pell Grants to Support Nontuition Expenses. Research Report
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Urban Institute, Center on Education Data and Policy, Sandy Baum, and Fanny Terrones
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Nontuition expenses--including housing, food, transportation, and miscellaneous expenses, in addition to books and supplies--constitute a significant financial burden for many students pursuing higher education, even if they receive grant aid to help them pay tuition and fees. Well-designed policy interventions at both the federal and state levels could effectively address the hardships some students face. A large increase in the maximum Pell grant to provide students additional funds for living expenses may seem like a straightforward solution, but that approach is not optimal. Doubling the maximum Pell grant would increase the aid most current full-time recipients receive by the same dollar amount, regardless of the size of their current Pell grant. In other words, it would double the grant for the lowest-income students, who currently receive the maximum, but would increase it by much larger proportions for those whose somewhat higher incomes qualify them for smaller grants. The program's cost would more than double. In this report, we propose alternative design options for a need-based basic living stipend. Awarding two Pell grants, with the second grant explicitly for nontuition expenses, would be less expensive and more targeted to the lowest-income students than doubling the maximum. Our preferred option would be a distinct need-based living stipend supplementing an increased Pell grant. The stipend would be standard, not based on individual cost of attendance, which is an inconsistent metric. The maximum stipend could be lower than the maximum Pell grant. The stipend would decline at a chosen rate as incomes increase. This approach would be most flexible and would be less expensive and better targeted than an increase in the maximum Pell grant that would give the same amount of funding to the lowest-income students. A federal matching program providing incentives to states to provide need-based living stipends would be a useful complement to this federal program and could tailor aid to local circumstances.
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- 2024
7. DKN-01 in Combination With Tislelizumab and Chemotherapy as First-Line Therapy in Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: DisTinGuish.
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Klempner, Samuel, Sonbol, Mohamad, Wainberg, Zev, Uronis, Hope, Chiu, Vi, Scott, Aaron, Iqbal, Syma, Tejani, Mohamedtaki, Chung, Vincent, Stilian, Melissa, Thoma, Mathis, Zhang, Ying, Kagey, Michael, Baum, Jason, Sirard, Cynthia, Altura, Rachel, and Ajani, Jaffer
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Humans ,Male ,Stomach Neoplasms ,Middle Aged ,Female ,Antibodies ,Monoclonal ,Humanized ,Aged ,Antineoplastic Combined Chemotherapy Protocols ,Esophagogastric Junction ,Adenocarcinoma ,Esophageal Neoplasms ,Adult ,Capecitabine ,Oxaliplatin ,Progression-Free Survival - Abstract
PURPOSE: The outcomes of anti-PD-1 agents plus fluoropyrimidine/platinum in frontline advanced gastroesophageal adenocarcinomas (aGEAs) remain poor. We investigated the safety, tolerability, and activity of fluoropyrimidine/oxaliplatin and tislelizumab with the DKK1-neutralizing antibody DKN-01 in aGEAs in a phase IIa open-label study. PATIENTS AND METHODS: Patients had untreated human epidermal growth factor receptor 2-negative aGEAs, RECIST v1.1 measurable disease, Eastern Cooperative Oncology Group (ECOG) performance status 0-1, and adequate organ function. Patients received intravenous DKN-01 300 mg once every 2 weeks, tislelizumab 200 mg once every 3 weeks, oxaliplatin 130 mg/m2 once every 3 weeks, and capecitabine 1,000 mg/m2 twice daily on days 1-15 of each 21-day cycle. The primary end point was safety and tolerability. Key secondary end points included objective response rate (ORR) by RECISTv1.1, progression-free survival (PFS), and overall survival (OS). RESULTS: Between September 18, 2020, and April 8, 2021, 25 patients were enrolled. All patients who received at least one dose of DKN-01 were included in the safety analysis. Most patients had gastroesophageal junction tumors, median age was 61 years, 76% were male, and 55% were ECOG of 0. All patients reported at least one treatment-emergent adverse event. The ORR was 73% (95% CI, 49.8 to 89.3), with a disease control rate of 95%. The ORR was 90% (95% CI, 55.5 to 99.7) in the DKK1-high tumor patients and 67% (95% CI, 29.9 to 92.5) in the DKK1-low tumor patients. The median PFS was 11.3 months (95% CI, 5.8 to 12.0) and the 12-month PFS rate was 33%. The median OS was 19.5 months (95% CI, 15.2 to 24.4) with a 12-month OS rate of 76% and an 18-month OS rate of 55%. CONCLUSION: DKN-01 can be safely combined with frontline fluoropyrimidine/oxaliplatin and tislelizumab and demonstrates encouraging activity independent of PD-L1 expression levels. A randomized phase II trial is ongoing (ClinicalTrials.gov identifier: NCT04363801).
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- 2025
8. Electron matter waves with internal torque
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Fang, Y., Kuttruff, J., and Baum, P.
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Physics - Optics ,Quantum Physics - Abstract
Angular momentum and torque are important principles for basic and applied physics on any spatial scales, for example, in elementary particles, cold gases, optical tweezers, quantum information technology, metamaterials, gyroscopes or astrophysical entities. Investigating or controlling angular momentum in atoms or sub-atomic structures requires torque on femtosecond and picometer scales, far below the capabilities of laser light. Here we shape the electrons in an electron microscope into wave packets with a time-dependent chirality and internal torque. We intersect the electron beam with chiral laser light to create discrete energy sidebands by multiple helical photon absorptions that create a correlation between orbital angular momentum and kinetic energy. Dispersion of these partial waves due to the electron rest mass then converts each single electron into a wave function with internal torque. Under our control, a left-handed matter wave becomes right-handed in femtosecond times. Such quantum objects will facilitate research on angular momentum and chirality on atomic and sub-atomic scales.
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- 2024
9. Achieving computational gains with quantum error correction primitives: Generation of long-range entanglement enhanced by error detection
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Liao, Haoran, Hartnett, Gavin S., Kakkar, Ashish, Tan, Adrian, Hush, Michael, Mundada, Pranav S., Biercuk, Michael J., and Baum, Yuval
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Quantum Physics - Abstract
The resource overhead required to achieve net computational benefits from quantum error correction (QEC) limits its utility while current systems remain constrained in size, despite exceptional progress in experimental demonstrations. In this paper, we demonstrate that the strategic application of QEC primitives without logical encoding can yield significant advantages on superconducting processors--relative to any alternative error-reduction strategy--while only requiring modest overhead. We first present a novel protocol for implementing long-range CNOT gates that relies on a unitarily-prepared Greenberger-Horne-Zeilinger (GHZ) state as well as a unitary disentangling step; the protocol natively introduces an error-detection process using the disentangled qubits as flags. We demonstrate that it achieves state-of-the-art gate fidelities of over 85% across up to 40 lattice sites, significantly and consistently outperforming the best alternative measurement-based protocol without introducing any additional ancilla qubits. We then apply sparse stabilizer measurements to generate large GHZ states by detecting bit-flip and amplitude-damping errors. Employing this technique in combination with deterministic error suppression, we generate a 75-qubit GHZ state exhibiting genuine multipartite entanglement, the largest reported to date. The generation requires no more than 9 ancilla qubits and the fraction of samples discarded due to errors grows no higher than 78%, far lower than previous discard fractions required for tests using comparable numbers of fully encoded qubits. This work in total represents compelling evidence that adopting QEC primitives on current-generation devices can deliver substantial net benefits., Comment: 8 pages, 5 figures (main text) + 9 pages, 10 figures (supplementary)
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- 2024
10. Comment on 'Attosecond electron microscopy and diffraction'
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Baum, P. and Ropers, C.
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Condensed Matter - Materials Science ,Physics - Applied Physics ,Physics - Optics - Abstract
A recent paper by Hui et al. (Ref. [1], Sci. Adv. 10, eadp5805 (2024)) claims the demonstration of 'Attosecond electron microscopy and diffraction' with laser-gated electron pulses. In this comment, we point out a series of physical and technical inconsistencies of the experiment and results. Beyond failing to show any microscopy, the reported concept does not produce properly gated electrons. Furthermore, the noise and signal levels of the presented data are statistically and quantitatively incompatible with the work's interpretation and attosecond dynamics in graphite. These inconsistencies render the claims and conclusions of Ref. [1] unsubstantiated and suggest that the data primarily show an interferometric artifact., Comment: Comment on doi.org/10.1126/sciadv.adp5805, originally posted as arXiv:2305.03014
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- 2024
11. Not Just a Dot: the complex UV morphology and underlying properties of Little Red Dots
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Rinaldi, P., Bonaventura, N., Rieke, G. H., Alberts, S., Caputi, K. I., Baker, W. M., Baum, S., Bhatawdekar, R., Bunker, A. J., Carniani, S., Curtis-Lake, E., D'Eugenio, F., Egami, E., Ji, Z., Hainline, K., Helton, J. M., Lin, X., Lyu, J., Johnson, B. D., Ma, Z., Maiolino, R., Pérez-González, P. G., Rieke, M., Robertson, B. E., Shivaei, I., Stone, M., Sun, Y., Tacchella, S., Übler, H., Williams, C. C., Willmer, C. N. A., Willott, C., Zhang, J., and Zhu, Y.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We analyze 99 photometrically selected Little Red Dots (LRDs) at z ~ 4-8 in the GOODS fields, leveraging ultra-deep JADES NIRCam short-wavelength (SW) data. We examine the morphology of 30 LRDs; the remaining 69 are predominantly compact, i.e. are strongly dominated by sources < 400 pc in diameter and lack extended components even in stacked SW band images. Among the LRDs selected for morphological analysis, 50% show at least two distinct, associated sources or galaxy components, while the others appear as single sources with highly asymmetric structures. We find median stellar masses of log10(M*/Msun) = 9.07(-0.08)(+0.11) for pure stellar models with Av ~ 1.16(+0.11)(-0.21) mag, and log10(M*/Msun) = 9.67(+0.17)(-0.27) for models including AGNs, where Av ~ 2.74(+0.55)(-0.71) mag, consistent with recent results showing LRDs tend to have high stellar masses and dust content when fitted with AGN models. NIRSpec spectra are available for 15 sources, 6 of which fall within the morphological analysis sample and show multiple components. Among these 15, broad H-alpha emission is detected in 40%, with full-width half-maximum (FWHM) ranging from 1200 to 2900 km/s. One source exhibits broad H-beta emission with FWHM = 2000 +/- 500 km/s. Analysis of line ratios probing the interstellar medium (ISM) reveals a composite nature, indicating AGN activity combined with stellar processes. These findings suggest LRDs have a mixed nature, with AGN signatures in some cases linked to disturbed morphologies observed at rest-frame UV wavelengths., Comment: 28 pages, 9 figures, 3 tables. Submitted to ApJ. Comments are welcome!
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- 2024
12. Cocoon shock, X-ray cavities and extended Inverse Compton emission in Hercules A: clues from Chandra observations
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Ubertosi, F., Gong, Y., Nulsen, P., Leahy, J. P., Gitti, M., McNamara, B. R., Gaspari, M., Singha, M., O'Dea, C., and Baum, S.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
We present a detailed analysis of jet activity in the radio galaxy 3C348 at the center of the galaxy cluster Hercules A. We use archival Chandra data to investigate the jet-driven shock front, the radio-faint X-ray cavities, the eastern jet, and the presence of extended Inverse Compton (IC) X-ray emission from the radio lobes. We detect two pairs of shocks: one in the north-south direction at 150 kpc from the center, and another in the east-west direction at 280 kpc. These shocks have Mach numbers of $\mathcal{M} = 1.65\pm0.05$ and $\mathcal{M} = 1.9\pm0.3$, respectively. Together, they form a complete cocoon around the large radio lobes. Based on the distance of the shocks from the center, we estimate that the corresponding jet outburst is 90-150 Myr old. We confirm the presence of two radio-faint cavities within the cocoon, misaligned from the lobes, each $\sim$100 kpc wide and 40-60 Myr old. A backflow from the radio lobes might explain why the cavities are dynamically younger than the cocoon shock front. We also detect non-thermal X-ray emission from the eastern jet and from the large radio lobes. The X-ray emission from the jet is visible at 80 kpc from the AGN and can be accounted for by an IC model with a mild Doppler boosting ($\delta\sim2.7$). A synchrotron model could explain the radio-to-X-ray spectrum only for very high Lorentz factors $\gamma\geq10^{8}$ of the electrons in the jet. For the large radio lobes, we argue that the X-ray emission has an IC origin, with a 1 keV flux density of $21.7\pm1.4\text{(statistical)}\pm1.3\text{(systematic)}$ nJy. A thermal model is unlikely, as it would require unrealistically high gas temperature, density, and pressure, along with a strong depolarization of the radio lobes, which are instead highly polarized. The IC detection, combined with the synchrotron flux density, suggests a magnetic field of $12\pm3\mu$G in the lobes., Comment: Accepted for publication in Astronomy & Astrophysics
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- 2024
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13. Adaptive Shock Compensation in the Multi-layer Network of Global Food Production and Trade
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Baum, Sophia, Laber, Moritz, Bruckner, Martin, Yang, Liuhuaying, Thurner, Stefan, and Klimek, Peter
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Economics - General Economics - Abstract
Global food production and trade networks are highly dynamic, especially in response to shortages when countries adjust their supply strategies. In this study, we examine adjustments across 123 agri-food products from 192 countries resulting in 23616 individual scenarios of food shortage, and calibrate a multi-layer network model to understand the propagation of the shocks. We analyze shock mitigation actions, such as increasing imports, boosting production, or substituting food items. Our findings indicate that these lead to spillover effects potentially exacerbating food inequality: an Indian rice shock resulted in a 5.8 % increase in rice losses in countries with a low Human Development Index (HDI) and a 14.2 % decrease in those with a high HDI. Considering multiple interacting shocks leads to super-additive losses of up to 12 % of the total available food volume across the global food production network. This framework allows us to identify combinations of shocks that pose substantial systemic risks and reduce the resilience of the global food supply.
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- 2024
14. Doubly unfolded adjacency spectral embedding of dynamic multiplex graphs
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Baum, Maximilian, Passino, Francesco Sanna, and Gandy, Axel
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Statistics - Methodology - Abstract
Many real-world networks evolve dynamically over time and present different types of connections between nodes, often called layers. In this work, we propose a latent position model for these objects, called the dynamic multiplex random dot product graph (DMPRDPG), which uses an inner product between layer-specific and time-specific latent representations of the nodes to obtain edge probabilities. We further introduce a computationally efficient spectral embedding method for estimation of DMPRDPG parameters, called doubly unfolded adjacency spectral embedding (DUASE). The DUASE estimates are proved to be consistent and asymptotically normally distributed, demonstrating the optimality properties of the proposed estimator. A key strength of our method is the encoding of time-specific node representations and layer-specific effects in separate latent spaces, which allows the model to capture complex behaviours while maintaining relatively low dimensionality. The embedding method we propose can also be efficiently used for subsequent inference tasks. In particular, we highlight the use of the ISOMAP algorithm in conjunction with DUASE as a way to efficiently capture trends and global changepoints within a network, and the use of DUASE for graph clustering. Applications on real-world networks describing geopolitical interactions between countries and financial news reporting demonstrate practical uses of our method., Comment: 36 pages, 4 figures
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- 2024
15. COVID-19 Learning Loss and Recovery in Brazil: Assessing Gaps across Social Groups
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Eveline de Medeiros Miranda and Donald R. Baum
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Students in over 150 countries experienced school closures throughout the COVID-19 pandemic. In the years following, a growing body of literature seeks to estimate the impacts of these education disruptions on a diverse set of outcomes, including student learning. This article adds to this research by examining causal evidence through a difference-in-differences framework (DID). Results suggest that school closures led to learning losses in math for high school seniors in public schools in the Federal District (DF) in Brazil. And while all racial groups experienced learning loss, White and Asian students experienced the most significant losses in 2020. We find no evidence of learning recovery from 2020 to 2021 for any racial groups, suggesting that learning losses persisted into school reopening. We do find, however, possible signs of recovery for female senior students compared to male students. Nevertheless, male and female performance differences are still prominent when analyzing data from 2016 to 2021. The utilization of critical policy analysis and the effectively maintained inequality frameworks can offer insights into significant learning disparities experienced by students.
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- 2024
16. Transparent Transparency Developing a Scheme for Understanding Transparency Requirements
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Baum, Deborah, Baum, Kevin, Zamani, Sasha, Bennoit, Christian, Werth, Dirk, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, and Yung, Moti, Editorial Board Member
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- 2025
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17. Understanding the Well-Being Literacy of EFL Learners: Towards a Framework of Learners' Knowledge and Skills
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Dávid Smid, Sarah Mercer, Carlos Murillo-Miranda, and Miri Tashma Baum
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Well-being has been recognized as a basic human right, a core determinant of success in education, and a skill that can be developed. In language education, the literature suggests that higher well-being is likely to lead to more classroom engagement and ultimately greater success for learners. For English language teachers, there is a need to understand what learners know about well-being, what kinds of support they feel they need, and how best to integrate such support into regular language teaching practice. This paper reports on a qualitative study using focus group data that set out to understand the well-being literacy of a group of 42 Austrian learners of English as a foreign language (EFL) in their final year of school. The findings reveal five categories in which learners demonstrated knowledge of well-being: conceptual understanding of well-being, factors impacting well-being, coping strategies, the role of systemic factors, and issues in the English language teaching context specifically. Based on analysis of these data, we present an initial practical framework for evaluating and guiding EFL student well-being literacy development.
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- 2024
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18. 'I'd Say, Transfer Schools Are Revolutionary': Alternative Schools as Revolutionary Spaces under Assault
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Mica Baum-Tuccillo, Varnica Arora, and Michelle Fine
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This paper documents the hopes, desires and structural betrayals experienced by young people attending transfer schools in New York City. Transfer schools enroll more than 15,000 students each year who are disproportionately young people of color, poor and working-class youth, from immigrant families, and youth with disabilities. Most have fallen behind on academic benchmarks. Many have been systematically pushed out of school through zero tolerance policies, high stakes testing cultures, and a lack of culturally relevant approaches to curriculum and pedagogy. This paper explores survey responses from 842 transfer school students, collected as part of a broader participatory action research study. Our analysis reveals that many transfer school students persist in the face of multiple obstacles that disrupt their educational progress, including material insecurity, previously alienating school experiences, housing insecurity, violence and struggles with mental health. Moreover, we find that students experience the transfer schools in this study as relationally rich, caring, intellectually rigorous, and mutually accountable learning communities that help them overcome obstacles that previously held them back. Our analysis confirms transfer school students' desires and persistence in the face of adversity and demonstrates the academic and socio-emotional commitments and impact of educators and counselors in transfer schools. Under current federal and state accountability frameworks, transfer schools are threatened by one-size-fits all metrics, punitive policies, and racialized austerity. As such, their importance and impact is consistently mismeasured and under-acknowledged. In this paper, we present evidence that these schools represent the radical rim of what is possible in public education, and we argue that we must support their efforts, honor their commitments, and establish a more equitable system for evaluating the essential work they do.
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- 2024
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19. Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome b.
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Awalt, Jon, Su, Wenyin, Nguyen, William, Loi, Katie, Jarman, Kate, Penington, Jocelyn, Ramesh, Saishyam, Fairhurst, Kate, Yeo, Tomas, Park, Heekuk, Uhlemann, Anne-Catrin, Chandra Maity, Bikash, De, Nirupam, Mukherjee, Partha, Chakraborty, Arnish, Churchyard, Alisje, Famodimu, Mufuliat, Delves, Michael, Baum, Jake, Mittal, Nimisha, Winzeler, Elizabeth, Papenfuss, Anthony, Chowdury, Mrittika, de Koning-Ward, Tania, Maier, Alexander, van Dooren, Giel, Baud, Delphine, Brand, Stephen, Fidock, David, Jackson, Paul, Cowman, Alan, Dans, Madeline, and Sleebs, Brad
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Antimalarial ,Cytochrome b ,Malaria ,Mitochondria ,Plasmodium ,Antimalarials ,Plasmodium falciparum ,Structure-Activity Relationship ,Cytochromes b ,Humans ,Animals ,Molecular Structure ,Dose-Response Relationship ,Drug ,Parasitic Sensitivity Tests ,Mice ,Cyclopropanes ,Amides ,Drug Resistance - Abstract
Drug resistance against antimalarials is rendering them increasingly ineffective and so there is a need for the development of new antimalarials. To discover new antimalarial chemotypes a phenotypic screen of the Janssen Jumpstarter library against the P. falciparum asexual stage was undertaken, uncovering the cyclopropyl carboxamide structural hit class. Structure-activity analysis revealed that each structural moiety was largely resistant to change, although small changes led to the frontrunner compound, WJM280, which has potent asexual stage activity (EC50 40 nM) and no human cell cytotoxicity. Forward genetics uncovered that cyclopropyl carboxamide resistant parasites have mutations and an amplification in the cytochrome b gene. Cytochrome b was then verified as the target with profiling against cytochrome b drug-resistant parasites and a mitochondrial oxygen consumption assay. Accordingly, the cyclopropyl carboxamide class was shown to have slow-acting asexual stage activity and activity against male gametes and exoerythrocytic forms. Enhancing metabolic stability to attain efficacy in malaria mouse models remains a challenge in the future development of this antimalarial chemotype.
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- 2024
20. Tambjamines as Fast-Acting Multistage Antimalarials.
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Kumar, Amrendra, Li, Yuexin, Dodean, Rozalia, Roth, Alison, Caridha, Diana, Madejczyk, Michael, Jin, Xiannu, Dennis, William, Lee, Patricia, Pybus, Brandon, Martin, Monica, Pannone, Kristina, Dinh, Hieu, Blount, Cameron, Chetree, Ravi, DeLuca, Jesse, Evans, Martin, Nadeau, Robert, Vuong, Chau, Leed, Susan, Black, Chad, Sousa, Jason, Nolan, Christina, Ceja, Frida, Rasmussen, Stephanie, Tumwebaze, Patrick, Rosenthal, Philip, Cooper, Roland, Rottmann, Matthias, Orjuela-Sanchez, Pamela, Meister, Stephan, Winzeler, Elizabeth, Delves, Michael, Matthews, Holly, Baum, Jake, Kirby, Robert, Burrows, Jeremy, Duffy, James, Peyton, David, Reynolds, Kevin, Kelly, Jane, and Kancharla, Papireddy
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antimalarials ,antiplasmodial ,fast-acting ,multistage ,natural products ,tambjamines ,Antimalarials ,Animals ,Plasmodium falciparum ,Mice ,Malaria ,Plasmodium yoelii ,Humans ,Mice ,SCID ,Disease Models ,Animal ,Erythrocytes ,Mice ,Inbred NOD ,Life Cycle Stages ,Malaria ,Falciparum - Abstract
Well-tolerated and novel antimalarials that can combat multiple stages of the parasite life cycle are desirable but challenging to discover and develop. Herein, we report results for natural product-inspired novel tambjamine antimalarials. We show that they are potent against liver, asexual erythrocytic, and sexual erythrocytic parasite life cycle stages. Notably, our lead candidate 1 (KAR425) displays excellent oral efficacy with complete clearance of parasites within 72 h of treatment in the humanized Plasmodium falciparum (NOD-scid) mouse model at 50 mg/kg × 4 days. Profiling of compound 1 demonstrated a fast in vitro killing profile. In addition, several other tambjamine analogues cured erythrocytic Plasmodium yoelii infections after oral doses of 30 and 50 mg/kg × 4 days in a murine model while exhibiting good safety and metabolic profiles. This study presents the first account of multiple-stage antiplasmodial activities with rapid killing profile in the tambjamine family.
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- 2024
21. Acting for the Right Reasons: Creating Reason-Sensitive Artificial Moral Agents
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Baum, Kevin, Dargasz, Lisa, Jahn, Felix, Gros, Timo P., and Wolf, Verena
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Computer Science - Artificial Intelligence ,Computer Science - Computers and Society ,Computer Science - Machine Learning - Abstract
We propose an extension of the reinforcement learning architecture that enables moral decision-making of reinforcement learning agents based on normative reasons. Central to this approach is a reason-based shield generator yielding a moral shield that binds the agent to actions that conform with recognized normative reasons so that our overall architecture restricts the agent to actions that are (internally) morally justified. In addition, we describe an algorithm that allows to iteratively improve the reason-based shield generator through case-based feedback from a moral judge., Comment: 8 pages, 2 figures, Workshop paper accepted to FEAR24 (IFM Workshop)
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- 2024
22. Resource-efficient context-aware dynamical decoupling embedding for arbitrary large-scale quantum algorithms
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Coote, Paul, Dimov, Roman, Maity, Smarak, Hartnett, Gavin S., Biercuk, Michael J., and Baum, Yuval
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Quantum Physics - Abstract
We introduce and implement GraphDD: an efficient method for real-time, circuit-specific, optimal embedding of dynamical decoupling (DD) into executable quantum algorithms. We demonstrate that for an arbitrary quantum circuit, GraphDD exactly refocuses both quasi-static single-qubit dephasing and crosstalk idling errors over the entire circuit, while using a minimal number of additional single-qubit gates embedded into idle periods. The method relies on a graph representation of the embedding problem, where the optimal decoupling sequence can be efficiently calculated using an algebraic computation that scales linearly with the number of idles. This allows optimal DD to be embedded during circuit compilation, without any calibration overhead, additional circuit execution, or numerical optimization. The method is generic and applicable to any arbitrary circuit; in compiler runtime the specific pulse-sequence solutions are tailored to the individual circuit, and consider a range of contextual information on circuit structure and device connectivity. We verify the ability of GraphDD to deliver enhanced circuit-level error suppression on 127-qubit IBM devices, showing that the optimal circuit-specific DD embedding resulting from GraphDD provides orders of magnitude improvements to measured circuit fidelities compared with standard embedding approaches available in Qiskit., Comment: 12 pages, 8 figures
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- 2024
23. Real-Time Human Action Recognition on Embedded Platforms
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Wang, Ruiqi, Wang, Zichen, Gao, Peiqi, Li, Mingzhen, Jeong, Jaehwan, Xu, Yihang, Lee, Yejin, Baum, Carolyn M., Connor, Lisa Tabor, and Lu, Chenyang
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Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
With advancements in computer vision and deep learning, video-based human action recognition (HAR) has become practical. However, due to the complexity of the computation pipeline, running HAR on live video streams incurs excessive delays on embedded platforms. This work tackles the real-time performance challenges of HAR with four contributions: 1) an experimental study identifying a standard Optical Flow (OF) extraction technique as the latency bottleneck in a state-of-the-art HAR pipeline, 2) an exploration of the latency-accuracy tradeoff between the standard and deep learning approaches to OF extraction, which highlights the need for a novel, efficient motion feature extractor, 3) the design of Integrated Motion Feature Extractor (IMFE), a novel single-shot neural network architecture for motion feature extraction with drastic improvement in latency, 4) the development of RT-HARE, a real-time HAR system tailored for embedded platforms. Experimental results on an Nvidia Jetson Xavier NX platform demonstrated that RT-HARE realizes real-time HAR at a video frame rate of 30 frames per second while delivering high levels of recognition accuracy.
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- 2024
24. Canalized Light Creates Directional and Switchable Surface Structures in Vanadium Dioxide
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Kazenwadel, Daniel, Neathery, Noel, and Baum, Peter
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Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Materials Science - Abstract
Materials with switchable nanostructured surfaces enable optical and electronic functionalities beyond those of natural materials. Here we report the creation of self-organized, re-writable, laser-induced surface structures in single-crystalline vanadium dioxide. We discover anisotropic features caused by canalized surface plasmon polaritons that can only propagate along one crystal axis. The nanostructures remain single-crystalline and preserve the raw material's metal-to-insulator transition, enabling femtosecond switching by temperature or light., Comment: {\dag}These authors contributed equally to this work
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- 2024
25. Mechanical problem solving in Goffin's cockatoos -- Towards modeling complex behavior
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Baum, Manuel, Roessler, Theresa, Osuna-Mascaró, Antonio J., Auersperg, Alice, and Brock, Oliver
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Quantitative Biology - Neurons and Cognition - Abstract
Research continues to accumulate evidence that Goffin's cockatoos (Cacatua goffiniana) can solve wide sets of mechanical problems, such as tool use, tool manufacture, and solving mechanical puzzles. However, the proximate mechanisms underlying this adaptive behavior are largely unknown. In this study, we analyze how three Goffin's cockatoos learn to solve a specific mechanical puzzle, a lockbox. The observed behavior results from the interaction between a complex environment (the lockbox) and different processes that jointly govern the animals' behavior. We thus jointly analyze the parrots' (1) engagement, (2) sensorimotor skill learning, and (3) action selection. We find that neither of these aspects could solely explain the animals' behavioral adaptation and that a plausible model of proximate mechanisms (including adaptation) should thus also jointly address these aspects. We accompany this analysis with a discussion of methods that may be used to identify such mechanisms. A major point we want to make is, that it is implausible to reliably identify a detailed model from the limited data of one or a few studies. Instead, we advocate for a more coarse approach that first establishes constraints on proximate mechanisms before specific, detailed models are formulated. We exercise this idea on the data we present in this study., Comment: Accepted for publication at journal Adaptive Behavior with SAGE publishing
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- 2024
26. The evolution of complexity and the transition to biochemical life
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Gagrani, Praful and Baum, David
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Quantitative Biology - Populations and Evolution ,Nonlinear Sciences - Adaptation and Self-Organizing Systems - Abstract
While modern physics and biology satisfactorily explain the passage from the Big Bang to the formation of Earth and the first cells to present-day life, respectively, the origins of biochemical life still remain an open question. Since life, as we know it, requires extremely long genetic polymers, any answer to the question must explain how an evolving system of polymers of ever-increasing length could come about on a planet that otherwise consisted only of small molecular building blocks. In this work, we show that, under realistic constraints, an abstract polymer model can exhibit dynamics such that attractors in the polymer population space with a higher average polymer length are also more probable. We generalize from the model and formalize the notions of complexity and evolution for chemical reaction networks with multiple attractors. The complexity of a species is defined as the minimum number of reactions needed to produce it from a set of building blocks, which in turn is used to define a measure of complexity for an attractor. A transition between attractors is considered to be a progressive evolution if the attractor with the higher probability also has a higher complexity. In an environment where only monomers are readily available, the attractor with a higher average polymer length is more complex. Thus, our abstract polymer model can exhibit progressive evolution for a range of thermodynamically plausible rate constants. We also formalize criteria for open-ended and historically-contingent evolution and explain the role of autocatalysis in obtaining them. Our work provides a basis for searching for prebiotically plausible scenarios in which long polymers can emerge and yield populations with even longer polymers., Comment: 29 pages, 10 figures
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- 2024
27. Soft Begging: Modular and Efficient Shielding of LLMs against Prompt Injection and Jailbreaking based on Prompt Tuning
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Ostermann, Simon, Baum, Kevin, Endres, Christoph, Masloh, Julia, and Schramowski, Patrick
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Computer Science - Cryptography and Security ,Computer Science - Artificial Intelligence ,Computer Science - Computation and Language - Abstract
Prompt injection (both direct and indirect) and jailbreaking are now recognized as significant issues for large language models (LLMs), particularly due to their potential for harm in application-integrated contexts. This extended abstract explores a novel approach to protecting LLMs from such attacks, termed "soft begging." This method involves training soft prompts to counteract the effects of corrupted prompts on the LLM's output. We provide an overview of prompt injections and jailbreaking, introduce the theoretical basis of the "soft begging" technique, and discuss an evaluation of its effectiveness.
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- 2024
28. Biomechanics-informed Non-rigid Medical Image Registration and its Inverse Material Property Estimation with Linear and Nonlinear Elasticity
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Min, Zhe, Baum, Zachary M. C., Saeed, Shaheer U., Emberton, Mark, Barratt, Dean C., Taylor, Zeike A., and Hu, Yipeng
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Computer Science - Computer Vision and Pattern Recognition - Abstract
This paper investigates both biomechanical-constrained non-rigid medical image registrations and accurate identifications of material properties for soft tissues, using physics-informed neural networks (PINNs). The complex nonlinear elasticity theory is leveraged to formally establish the partial differential equations (PDEs) representing physics laws of biomechanical constraints that need to be satisfied, with which registration and identification tasks are treated as forward (i.e., data-driven solutions of PDEs) and inverse (i.e., parameter estimation) problems under PINNs respectively. Two net configurations (i.e., Cfg1 and Cfg2) have also been compared for both linear and nonlinear physics model. Two sets of experiments have been conducted, using pairs of undeformed and deformed MR images from clinical cases of prostate cancer biopsy. Our contributions are summarised as follows. 1) We developed a learning-based biomechanical-constrained non-rigid registration algorithm using PINNs, where linear elasticity is generalised to the nonlinear version. 2) We demonstrated extensively that nonlinear elasticity shows no statistical significance against linear models in computing point-wise displacement vectors but their respective benefits may depend on specific patients, with finite-element (FE) computed ground-truth. 3) We formulated and solved the inverse parameter estimation problem, under the joint optimisation scheme of registration and parameter identification using PINNs, whose solutions can be accurately found by locating saddle points., Comment: Accepted at MICCAI 2024
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- 2024
29. Jetted subgalactic-size radio sources in merging galaxies -- A jet redirection scenario
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Stanghellini, C., Orienti, M., Spingola, C., Zanichelli, A., Dallacasa, D., Cassaro, P., O'Dea, C. P., Baum, S. A., and Pérez-Torres, M.
- Subjects
Astrophysics - Astrophysics of Galaxies - Abstract
Context: The long-standing question concerning jetted subgalactic-size (JSS) radio sources is whether they will evolve into large radio galaxies, die before escaping the host galaxy, or remain indefinitely confined to their compact size. Aims: Our main goal is to propose a scenario that explains the relative number of JSS radio sources and their general properties. Methods: We studied the parsec-scale radio morphology of a complete sample of 21 objects using Very Long Baseline Array (VLBA) observations at various frequencies and analyzed the morphological characteristics of their optical hosts. Results: Many of these radio sources exhibit radio morphologies consistent with transverse motions of their bright edges and are found in dynamically disturbed galaxies. VLBA images suggest the possible presence of large-angle, short-period precessing jets, and an orbital motion of the radio-loud active galactic nucleus (AGN) in a dual or binary system. The majority of JSS radio sources appear to be in systems in different stages of their merging evolution. Conclusions: We propose a scenario where rapid jet redirection, through precession or orbital motion, prevents the jet from penetrating the interstellar medium (ISM) sufficiently to escape the host galaxy. Most JSS radio sources remain compact due to their occurrence in merging galaxies., Comment: 35 pages, 24 figures, 4 tables, accepted for publication in Astronomy & Astrophysics
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- 2024
30. Mass-Balance MRV for Carbon Dioxide Removal by Enhanced Rock Weathering: Methods, Simulation, and Inference
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Baum, Mark, Liu, Henry, Schacht, Lily, Schneider, Jake, and Yap, Mary
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Statistics - Applications - Abstract
Carbon dioxide will likely need to be removed from the atmosphere to avoid significant future warming and climate change. Technologies are being developed to remove large quantities of carbon from the atmosphere. Enhanced rock weathering (ERW), where fine-grained silicate minerals are spread on soil, is a promising carbon removal method that can also support crop yields and maintain overall soil health. Quantifying the amount of carbon removed by ERW is crucial for understanding the potential of ERW globally and for building trust in commercial operations. However, reliable and scalable quantification in complex media like soil is challenging and there is not yet a consensus on the best method of doing so. Here we discuss mass-balance methods, where stocks of base cations in soil are monitored over time to infer the amount of inorganic carbon brought into solution by weathering reactions. First, we review the fundamental concepts of mass-balance methods and explain different ways of approaching the mass-balance problem. Then we discuss experimental planning and data collection, suggesting some best practices. Next, we present a software package designed to facilitate a range of tasks in ERW like uncertainty analysis, planning field trials, and validating statistical methods. Finally, we briefly review ways of estimating carbon removal using mass balance before discussing some advantages of Bayesian inference in this context and presenting an example Bayesian model. The model is fit to simulated data and recovers the correct answer with a clear representation of uncertainty.
- Published
- 2024
31. Long-term clinical outcome and exercise capacity in SARS-CoV-2-positive elite athletes
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Diebold, Katharina, Zacher, Jonas, Baum, Klaus, Reuter, Hannes, Schneeweis, Christopher, Schramm, Thomas, Schifferdecker, Inga, Vassiliadis, Argiris, and Predel, Hans-Georg
- Published
- 2025
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32. Exploring Eco-Grief, Transformative Learning, and Action in Environmental Observers
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Zurba, Melanie, Baum-Talmor, Polina, Park, Andrew, Rudenko, Kateryna, Mendritzki, Erica, Woodgate, Roberta L, Binkley, Lisa, and Busolo, David
- Published
- 2025
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33. Automation bias in AI-assisted detection of cerebral aneurysms on time-of-flight MR angiography
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Kim, Su Hwan, Schramm, Severin, Riedel, Evamaria Olga, Schmitzer, Lena, Rosenkranz, Enrike, Kertels, Olivia, Bodden, Jannis, Paprottka, Karolin, Sepp, Dominik, Renz, Martin, Kirschke, Jan, Baum, Thomas, Maegerlein, Christian, Boeckh-Behrens, Tobias, Zimmer, Claus, Wiestler, Benedikt, and Hedderich, Dennis M.
- Published
- 2025
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34. Opportunistic osteoporosis screening in intraoperative CT can accurately identify patients with low volumetric bone mineral density and osteoporosis during spine surgery
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Rühling, Sebastian, Petzsche, Moritz R. Hernandez, Löffler, Maximilian T., Sollmann, Nico, Baum, Thomas, Bodden, Jannis, Schwarting, Julian, Lange, Nicole, Aftahy, Kaywan, Wostrack, Maria, Zimmer, Claus, and Kirschke, Jan S.
- Published
- 2025
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35. The role of spatial processing in verbal serial order working memory
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Tian, Yingxue and Fischer-Baum, Simon
- Published
- 2025
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36. Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction and obesity: a secondary analysis of the SUMMIT trial
- Author
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Borlaug, Barry A., Zile, Michael R., Kramer, Christopher M., Baum, Seth J., Hurt, Karla, Litwin, Sheldon E., Murakami, Masahiro, Ou, Yang, Upadhyay, Navneet, and Packer, Milton
- Published
- 2025
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37. Müdigkeit in der hausärztlichen Praxis
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Kornder, Nele, Maisel, Peter, Baum, Erika, and Lindner, Nicole
- Published
- 2025
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38. Predicting work ability impairment in post COVID-19 patients: a machine learning model based on clinical parameters
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Jebrini, Tarek, Ruzicka, Michael, Völk, Felix, Fonseca, Gerardo Jesus Ibarra, Pernpruner, Anna, Benesch, Christopher, Valdinoci, Elisabeth, von Baum, Max, Weigl, Martin, Subklewe, Marion, von Bergwelt-Baildon, Michael, Roider, Julia, Mayerle, Julia, Heindl, Bernhard, Adorjan, Kristina, and Stubbe, Hans Christian
- Published
- 2025
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39. Baby Buddy App for Breastfeeding and Behavior Change: Retrospective Study of the App Using the Behavior Change Wheel
- Author
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Musgrave, Loretta M, Baum, Alison, Perera, Nilushka, Homer, Caroline SE, and Gordon, Adrienne
- Subjects
Information technology ,T58.5-58.64 ,Public aspects of medicine ,RA1-1270 - Abstract
BackgroundBreastfeeding plays a major role in the health of mothers and babies and has the potential to positively shape an individual’s life both in the short and long term. In the United Kingdom (UK), although 81% of women initiate breastfeeding, only 1% of women breastfeed exclusively to 6 months as recommended by the World Health Organization. In the UK, women who are socially disadvantaged and younger are less likely to breastfeed at 6 to 8 weeks postpartum. One strategy that aims to improve these statistics is the Baby Buddy app, which has been designed and implemented by the UK charity Best Beginnings to be a universal intervention to help reduce health inequalities, including those in breastfeeding. ObjectiveThis study aimed to retrospectively examine the development of Baby Buddy by applying the Behavior Change Wheel (BCW) framework to understand how it might increase breastfeeding self-efficacy, knowledge, and confidence. MethodsRetrospective application of the BCW was completed after the app was developed and embedded into maternity services. A three-stage process evaluation used triangulation methods and formalized tools to gain an understanding of the potential mechanisms and behaviors used in apps that are needed to improve breastfeeding rates in the UK. First, we generated a behavioral analysis by mapping breastfeeding barriers and enablers onto the Capability, Opportunity, and Motivation-Behavior (COM-B) system using documents provided by Best Beginnings. Second, we identified the intervention functions and policy categories used. Third, we linked these with the behavior change techniques identified in the app breastfeeding content using the Behavior Change Techniques Taxonomy (BCTTv1). ResultsBaby Buddy is a well-designed platform that could be used to change breastfeeding behaviors. Findings from stage one showed that Best Beginnings had defined breastfeeding as a key behavior requiring support and demonstrated a thorough understanding of the context in which breastfeeding occurs, the barriers and enablers of breastfeeding, and the target actions needed to support breastfeeding. In stage two, Best Beginnings had used intervention and policy functions to address the barriers and enablers of breastfeeding. In stage three, Baby Buddy had been assessed for acceptability, practicability, effectiveness, affordability, safety, and equity. Several behavior change techniques that could assist women with decision making around breastfeeding (eg, information about health consequences and credible sources) and possibly affect attitudes and self-efficacy were identified. Of the 39 videos in the app, 19 (49%) addressed physical capabilities related to breastfeeding and demonstrated positive breastfeeding behaviors. ConclusionsApplying a theoretical framework retrospectively to a mobile app is possible and results in useful information to understand potential health benefits and to inform future development. Future research should assess which components and behavioral techniques in the app are most effective in changing behavior and supporting breastfeeding.
- Published
- 2021
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40. Variation in Community College Funding Levels: A Focus on Equity. Research Report
- Author
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Urban Institute, Sandy Baum, and Jason Cohn
- Abstract
Funding for community colleges varies significantly, even within the same state. Several factors account for these differences, including more generous funding for smaller institutions to compensate for their higher costs per student, unequal local funding from property tax revenues, and political forces. In theory, this variation could lead to systemic inequities in funding levels by race, ethnicity, and economic status. Such inequities could arise if students from historically underserved groups are concentrated in community colleges that receive the lowest levels of funding from state and local appropriations. This analysis finds no such consistent patterns across the nation but does find concerning patterns in a few states. Significant differences in funding levels across states are likely to be the result of differences in state and local postsecondary support at all levels, priorities attached to two-year versus four-year institutions, and methods of allocating resources among eligible institutions. In addition, allocation systems, combined with demographic differences among community college students, can create sizeable differences in funding levels among the institutions within a state. This analysis focuses on these funding differences across community colleges within states, investigating the prevalence of differences in state and local funding levels between Black students and all other students, Hispanic students and all other students, and low-income students (proxied by the receipt of Pell grants) and higher-income students.
- Published
- 2023
41. Nontuition Expenses: A Framework for Developing Policy Solutions. Research Report
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Urban Institute, Center on Education Data and Policy, Sandy Baum, Bryan J. Cook, Fanny Terrones, and Elise Colin
- Abstract
Discussions about college affordability often revolve around helping students pay their tuition and fees. But nontuition expenses, including food, housing, and other living expenses, make up a large portion of student budgets and contribute to increased student debt. These expenses can be a barrier to student enrollment and completion. Lack of information about the true full cost of attendance, stringent requirements to qualify for income support benefits, and limited grant aid make it hard for many students to access enough resources to cover their basic needs. In this report, we summarize our findings emerging from research and a convening we hosted on nontuition expenses. Currently, there is no standardized way to measure cost of attendance at institutions, making it difficult for students to compare nontuition costs across schools. Providing students personalized information about what their food, housing, and other living expenses may look like allows them to plan for the school year but is distinct from practical solutions for measuring student need for financial aid purposes. Doubling the Pell grant is a common suggestion when discussing the cost of education, and incorporating some level of basic living expenses, in addition to the costs of books and supplies, into estimates of adequate grant aid would be constructive. But increasing the Pell grant is insufficient, as using it explicitly to cover living expenses could lack political support and may lead to unintended consequences, such as tuition increases. Based on these findings, state and federal policymakers can do more to support students who cannot afford nontuition expenses through changes to federal, state, and institution-level policies. Both enabling students to have access to income support benefits and more generous grant aid are central to policy efforts for addressing financial barriers to student access and success. Increases in need-based financial aid from federal and state governments, as well as institutions, are important. But we should not view low-income students as entirely distinct from other low-income adults, and education policy alone cannot be responsible for meeting students' basic needs.
- Published
- 2023
42. Content and Form: Authorship Attribution and Pseudonymity in Ancient Speeches, Letters, Lectures, and Translations—A Rejoinder to Bart Ehrman
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Baum, Armin D.
- Published
- 2017
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43. Responsible and Trusted AI: An Interdisciplinary Perspective
- Author
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Helfer, Thorsten, Baum, Kevin, Sesing-Wagenpfeil, Andreas, Schmidt, Eva, Langer, Markus, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, and Yung, Moti, Editorial Board Member
- Published
- 2025
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44. One Tree to Rule Them All: Optimizing GGM Trees and OWFs for Post-Quantum Signatures
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Baum, Carsten, Beullens, Ward, Mukherjee, Shibam, Orsini, Emmanuela, Ramacher, Sebastian, Rechberger, Christian, Roy, Lawrence, Scholl, Peter, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Chung, Kai-Min, editor, and Sasaki, Yu, editor
- Published
- 2025
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45. Taming the AI Monster: Monitoring of Individual Fairness for Effective Human Oversight
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Baum, Kevin, Biewer, Sebastian, Hermanns, Holger, Hetmank, Sven, Langer, Markus, Lauber-Rönsberg, Anne, Sterz, Sarah, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Neele, Thomas, editor, and Wijs, Anton, editor
- Published
- 2025
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46. Evaluierung der Maßnahmen des Onlinezugangsgesetzes (OZG) in Bezug auf die Anwendbarkeit der Methoden der künstlichen Intelligenz durch das Self-Enforcing Network (SEN)
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Brandt, Doris, Baum, Silvan, Klüver, Christina, editor, and Klüver, Jürgen, editor
- Published
- 2025
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47. CoDA: Interactive Segmentation and Morphological Analysis of Dendroid Structures Exemplified on Stony Cold-Water Corals
- Author
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Schmitt, Kira, Titschack, Jürgen, and Baum, Daniel
- Subjects
Computer Science - Computer Vision and Pattern Recognition - Abstract
Herein, we present CoDA, the Coral Dendroid structure Analyzer, a visual analytics suite that allows for the first time to investigate the ontogenetic morphological development of complex dendroid coral colonies, exemplified on three important framework-forming dendroid cold-water corals: Lophelia pertusa (Linnaeus, 1758), Madrepora oculata (Linnaeus, 1758), and Goniocorella dumosa (Alcock, 1902). Input to CoDA is an initial instance segmentation of the coral polyp cavities (calices), from which it estimates the skeleton tree of the colony and extracts classical morphological measurements and advanced shape features of the individual corallites. CoDA also works as a proofreading and error correction tool by helping to identify wrong parts in the skeleton tree and providing tools to quickly correct these errors. The final skeleton tree enables the derivation of additional information about the calices/corallite instances that otherwise could not be obtained, including their ontogenetic generation and branching patterns - the basis of a fully quantitative statistical analysis of the coral colony morphology. Part of CoDA is CoDAGraph, a feature-rich link-and-brush user interface for visualizing the extracted features and 2D graph layouts of the skeleton tree, enabling the real-time exploration of complex coral colonies and their building blocks, the individual corallites and branches. In the future, we expect CoDA to greatly facilitate the analysis of large stony corals of different species and morphotypes, as well as other dendroid structures, enabling new insights into the influence of genetic and environmental factors on their ontogenetic morphological development.
- Published
- 2024
48. An insertable glucose sensor using a compact and cost-effective phosphorescence lifetime imager and machine learning
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Goncharov, Artem, Gorocs, Zoltan, Pradhan, Ridhi, Ko, Brian, Ajmal, Ajmal, Rodriguez, Andres, Baum, David, Veszpremi, Marcell, Yang, Xilin, Pindrys, Maxime, Zheng, Tianle, Wang, Oliver, Ramella-Roman, Jessica C., McShane, Michael J., and Ozcan, Aydogan
- Subjects
Physics - Medical Physics ,Computer Science - Machine Learning ,Physics - Applied Physics ,Physics - Biological Physics - Abstract
Optical continuous glucose monitoring (CGM) systems are emerging for personalized glucose management owing to their lower cost and prolonged durability compared to conventional electrochemical CGMs. Here, we report a computational CGM system, which integrates a biocompatible phosphorescence-based insertable biosensor and a custom-designed phosphorescence lifetime imager (PLI). This compact and cost-effective PLI is designed to capture phosphorescence lifetime images of an insertable sensor through the skin, where the lifetime of the emitted phosphorescence signal is modulated by the local concentration of glucose. Because this phosphorescence signal has a very long lifetime compared to tissue autofluorescence or excitation leakage processes, it completely bypasses these noise sources by measuring the sensor emission over several tens of microseconds after the excitation light is turned off. The lifetime images acquired through the skin are processed by neural network-based models for misalignment-tolerant inference of glucose levels, accurately revealing normal, low (hypoglycemia) and high (hyperglycemia) concentration ranges. Using a 1-mm thick skin phantom mimicking the optical properties of human skin, we performed in vitro testing of the PLI using glucose-spiked samples, yielding 88.8% inference accuracy, also showing resilience to random and unknown misalignments within a lateral distance of ~4.7 mm with respect to the position of the insertable sensor underneath the skin phantom. Furthermore, the PLI accurately identified larger lateral misalignments beyond 5 mm, prompting user intervention for re-alignment. The misalignment-resilient glucose concentration inference capability of this compact and cost-effective phosphorescence lifetime imager makes it an appealing wearable diagnostics tool for real-time tracking of glucose and other biomarkers., Comment: 24 Pages, 4 Figures
- Published
- 2024
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49. Quantum optimization using a 127-qubit gate-model IBM quantum computer can outperform quantum annealers for nontrivial binary optimization problems
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Sachdeva, Natasha, Hartnett, Gavin S., Maity, Smarak, Marsh, Samuel, Wang, Yulun, Winick, Adam, Dougherty, Ryan, Canuto, Daniel, Chong, You Quan, Hush, Michael, Mundada, Pranav S., Bentley, Christopher D. B., Biercuk, Michael J., and Baum, Yuval
- Subjects
Quantum Physics - Abstract
We introduce a comprehensive quantum solver for binary combinatorial optimization problems on gate-model quantum computers that outperforms any published alternative and consistently delivers correct solutions for problems with up to 127 qubits. We provide an overview of the internal workflow, describing the integration of a customized ansatz and variational parameter update strategy, efficient error suppression in hardware execution, and QPU-overhead-free post-processing to correct for bit-flip errors. We benchmark this solver on IBM quantum computers for several classically nontrivial unconstrained binary optimization problems -- the entire optimization is conducted on hardware with no use of classical simulation or prior knowledge of the solution. First, we demonstrate the ability to correctly solve Max-Cut instances for random regular graphs with a variety of densities using up to 120 qubits, where the graph topologies are not matched to device connectivity. Next, we apply the solver to higher-order binary optimization and successfully search for the ground state energy of a 127-qubit spin-glass model with linear, quadratic, and cubic interaction terms. Use of this new quantum solver increases the likelihood of finding the minimum energy by up to $\sim1,500\times$ relative to published results using a DWave annealer, and it can find the correct solution when the annealer fails. Furthermore, for both problem types, the Q-CTRL solver outperforms a heuristic local solver used to indicate the relative difficulty of the problems pursued. Overall, these results represent the largest quantum optimizations successfully solved on hardware to date, and demonstrate the first time a gate-model quantum computer has been able to outperform an annealer for a class of binary optimization problems., Comment: 19 pages, 8 figures
- Published
- 2024
50. The Final Frontier for Proton Decay
- Author
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Baum, Sebastian, Little, Cassandra, Sala, Paola, Spitz, Joshua, and Stengel, Patrick
- Subjects
High Energy Physics - Phenomenology ,Astrophysics - Instrumentation and Methods for Astrophysics ,High Energy Physics - Experiment ,Physics - Instrumentation and Detectors - Abstract
We present a novel experimental concept to search for proton decay. Using paleo-detectors, ancient minerals acquired from deep underground which can hold traces of charged particles, it may be possible to conduct a search for $p \to \bar{\nu} K^+$ via the track produced at the endpoint of the kaon. Such a search is not possible on Earth due to large atmospheric-neutrino-induced backgrounds. However, the Moon offers a reprieve from this background, since the conventional component of the cosmic-ray-induced neutrino flux at the Moon is significantly suppressed due to the Moon's lack of atmosphere. For a 100 g, $10^9$ year old (100 kton$\cdot$year exposure) sample of olivine extracted from the Moon, we expect about 0.5 kaon endpoints due to neutrino backgrounds, including secondary interactions. If such a lunar paleo-detector sample can be acquired and efficiently analyzed, proton decay sensitivity exceeding $\tau_p\sim10^{34}$ years may be achieved, competitive with Super-Kamiokande's current published limit ($\tau_p>5.9\times 10^{33}$ years at 90% CL) and the projected reach of DUNE and Hyper-Kamiokande in the $p \to \bar{\nu} K^+$ channel. This concept is clearly futuristic, not least since it relies on extracting mineral samples from a few kilometers below the surface of the Moon and then efficiently scanning them for kaon endpoint induced crystal defects with sub-micron-scale resolution. However, the search for proton decay is in urgent need of a paradigm shift, and paleo-detectors could provide a promising alternative to conventional experiments., Comment: 12 pages, 4 figures
- Published
- 2024
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