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1. Association between exposure to multiple air pollutants, transportation noise and cause-specific mortality in adults in Switzerland

Author

Vienneau, Danielle, Stafoggia, Massimo, Rodopoulou, Sophia, Chen, Jie, Atkinson, Richard W., Bauwelinck, Mariska, Klompmaker, Jochem O., Oftedal, Bente, Andersen, Zorana J., Janssen, Nicole A. H., So, Rina, Lim, Youn-Hee, Flückiger, Benjamin, Ducret-Stich, Regina, Röösli, Martin, Probst-Hensch, Nicole, Künzli, Nino, Strak, Maciek, Samoli, Evangelia, de Hoogh, Kees, Brunekreef, Bert, and Hoek, Gerard

Published
2023
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2. Long-Term Exposure to Low-Level P[M.sub.2.5] and Mortality: Investigation of Heterogeneity by Harmonizing Analyses in Large Cohort Studies in Canada, United States, and Europe

Author

Chen, Jie, Braun, Danielle, Christidis, Tanya, Cork, Michael, Rodopoulou, Sophia, Samoli, Evangelia, Stafoggia, Massimo, Wolf, Kathrin, Wu, Xiao, Yuchi, Weiran, Andersen, Zorana J., Atkinson, Richard, Bauwelinck, Mariska, de Hoogh, Kees, Janssen, Nicole A.H., Katsouyanni, Klea, Klompmaker, Jochem O., Kristoffersen, Doris Tove, Lim, Youn-Hee, Oftedal, Bente, Strak, Maciej, Vienneau, Danielle, Zhang, Jiawei, Burnett, Richard T., Hoek, Gerard, Dominici, Francesca, Brauer, Michael, and Brunekreef, Bert

Subjects
Mortality -- Statistics -- Environmental aspects -- Health aspects -- Europe -- Canada -- United States, Air pollution -- Statistics -- Health aspects, Particles -- Statistics -- Health aspects, Environmental issues, Health
Abstract

BACKGROUND: Studies across the globe generally reported increased mortality risks associated with particulate matter with aerodynamic diameter [less than or equal to]2.5 [micro]m (P[M.sub.2.5]) exposure with large heterogeneity in the magnitude of reported associations and the shape of concentration-response functions (CRFs). We aimed to evaluate the impact of key study design factors (including confounders, applied exposure model, population age, and outcome definition) on P[M.sub.2.5] effect estimates by harmonizing analyses on three previously published large studies in Canada [Mortality-Air Pollution Associations in Low Exposure Environments (MAPLE), 1991-2016], the United States (Medicare, 2000-2016), and Europe [Effects of Low-Level Air Pollution: A Study in Europe (ELAPSE), 2000-2016] as much as possible. METHODS: We harmonized the study populations to individuals 65+ years of age, applied the same satellite-derived P[M.sub.2.5] exposure estimates, and selected the same sets of potential confounders and the same outcome. We evaluated whether differences in previously published effect estimates across cohorts were reduced after harmonization among these factors. Additional analyses were conducted to assess the influence of key design features on estimated risks, including adjusted covariates and exposure assessment method. A combined CRF was assessed with meta-analysis based on the extended shape-constrained health impact function (eSCHIF). RESULTS: More than 81 million participants were included, contributing 692 million person-years of follow-up. Hazard ratios and 95% confidence intervals (CIs) for all-cause mortality associated with a 5-[micro]g/[m.sup.3] increase in P[M.sub.2.5] were 1.039 (1.032, 1.046) in MAPLE, 1.025 (1.021, 1.029) in Medicare, and 1.041 (1.014, 1.069) in ELAPSE. Applying a harmonized analytical approach marginally reduced difference in the observed associations across the three studies. Magnitude of the association was affected by the adjusted covariates, exposure assessment methodology, age of the population, and marginally by outcome definition. Shape of the CRFs differed across cohorts but generally showed associations down to the lowest observed P[M.sub.2.5] levels. A common CRF suggested a monotonically increased risk down to the lowest exposure level. https://doi.org/10.1289/EHP12141, Introduction Ambient particulate matter (PM) pollution has been identified as a leading risk factor for global disease burden. (1) Evaluating the risks attributable to PM with aerodynamic diameter [less than [...]

Published
2023
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3. Comparison of traditional Cox regression and causal modeling to investigate the association between long-term air pollution exposure and natural-cause mortality within European cohorts

Author

Wolf, Kathrin, Rodopoulou, Sophia, Chen, Jie, Andersen, Zorana J., Atkinson, Richard W., Bauwelinck, Mariska, Janssen, Nicole A.H., Kristoffersen, Doris Tove, Lim, Youn-Hee, Oftedal, Bente, Strak, Maciek, Vienneau, Danielle, Zhang, Jiawei, Brunekreef, Bert, Hoek, Gerard, Stafoggia, Massimo, and Samoli, Evangelia

Published
2023
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4. Long-term exposure to elemental components of fine particulate matter and all-natural and cause-specific mortality in a Danish nationwide administrative cohort study

Author

So, Rina, Chen, Jie, Stafoggia, Massimo, de Hoogh, Kees, Katsouyanni, Klea, Vienneau, Danielle, Samoli, Evangelia, Rodopoulou, Sophia, Loft, Steffen, Lim, Youn-Hee, Westendorp, Rudi G.J., Amini, Heresh, Cole-Hunter, Thomas, Bergmann, Marie, Shahri, Seyed Mahmood Taghavi, Zhang, Jiawei, Maric, Matija, Mortensen, Laust H., Bauwelinck, Mariska, Klompmaker, Jochem O., Atkinson, Richard W., Janssen, Nicole A.H., Oftedal, Bente, Renzi, Matteo, Forastiere, Francesco, Strak, Maciek, Brunekreef, Bert, Hoek, Gerard, and Andersen, Zorana J.

Published
2023
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6. Long-term exposure to low ambient air pollution concentrations and mortality among 28 million people: results from seven large European cohorts within the ELAPSE project

Author

Stafoggia, Massimo, Oftedal, Bente, Chen, Jie, Rodopoulou, Sophia, Renzi, Matteo, Atkinson, Richard W, Bauwelinck, Mariska, Klompmaker, Jochem O, Mehta, Amar, Vienneau, Danielle, Andersen, Zorana J, Bellander, Tom, Brandt, Jørgen, Cesaroni, Giulia, de Hoogh, Kees, Fecht, Daniela, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hvidtfeldt, Ulla A, Jöckel, Karl-Heinz, Jørgensen, Jeanette T, Katsouyanni, Klea, Ketzel, Matthias, Kristoffersen, Doris Tove, Lager, Anton, Leander, Karin, Liu, Shuo, Ljungman, Petter L S, Nagel, Gabriele, Pershagen, Göran, Peters, Annette, Raaschou-Nielsen, Ole, Rizzuto, Debora, Schramm, Sara, Schwarze, Per E, Severi, Gianluca, Sigsgaard, Torben, Strak, Maciek, van der Schouw, Yvonne T, Verschuren, Monique, Weinmayr, Gudrun, Wolf, Kathrin, Zitt, Emanuel, Samoli, Evangelia, Forastiere, Francesco, Brunekreef, Bert, Hoek, Gerard, and Janssen, Nicole A H

Published
2022
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7. Long-term exposure to low-level ambient air pollution and incidence of stroke and coronary heart disease: a pooled analysis of six European cohorts within the ELAPSE project

Author

Wolf, Kathrin, Hoffmann, Barbara, Andersen, Zorana J, Atkinson, Richard W, Bauwelinck, Mariska, Bellander, Tom, Brandt, Jørgen, Brunekreef, Bert, Cesaroni, Giulia, Chen, Jie, de Faire, Ulf, de Hoogh, Kees, Fecht, Daniela, Forastiere, Francesco, Gulliver, John, Hertel, Ole, Hvidtfeldt, Ulla Arthur, Janssen, Nicole A H, Jørgensen, Jeanette T, Katsouyanni, Klea, Ketzel, Matthias, Klompmaker, Jochem O, Lager, Anton, Liu, Shuo, MacDonald, Conor J, Magnusson, Patrik K E, Mehta, Amar J, Nagel, Gabriele, Oftedal, Bente, Pedersen, Nancy L, Pershagen, Göran, Raaschou-Nielsen, Ole, Renzi, Matteo, Rizzuto, Debora, Rodopoulou, Sophia, Samoli, Evangelia, van der Schouw, Yvonne T, Schramm, Sara, Schwarze, Per, Sigsgaard, Torben, Sørensen, Mette, Stafoggia, Massimo, Strak, Maciek, Tjønneland, Anne, Verschuren, W M Monique, Vienneau, Danielle, Weinmayr, Gudrun, Hoek, Gerard, Peters, Annette, and Ljungman, Petter L S

Published
2021
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10. Residential Exposure to Urban Trees and Medication Sales for Mood Disorders and Cardiovascular Disease in Brussels, Belgium: An Ecological Study

Author

Chi, Dengkai, Aerts, Raf, Van Nieuwenhuyse, An, Bauwelinck, Mariska, Demoury, Claire, Plusquin, Michelle, Nawrot, Tim S., Casas, Lidia, and Somers, Ben

Subjects
Brussels, Belgium (City) -- Environmental aspects -- Health aspects, Environmental health -- Methods, Trees in cities -- Health aspects -- Psychological aspects -- Environmental aspects, Cardiovascular diseases -- Care and treatment -- Environmental aspects, Affective disorders -- Care and treatment -- Environmental aspects, Environmental issues, Health
Abstract

Background: The available evidence for positive associations between urban trees and human health is mixed, partly because the assessment of exposure to trees is often imprecise because of, for instance, exclusion of trees in private areas and the lack of three- dimensional (3D) exposure indicators (e.g., crown volume). Objectives: We aimed to quantify all trees and relevant 3D structural traits in Brussels (Belgium) and to investigate associations between the number of trees, tree traits, and sales of medication commonly prescribed for mood disorders and cardiovascular disease. Methods: We developed a workflow to automatically isolate all individual trees from airborne light detection and ranging (LiDAR) data collected in 2012. Trait data were subsequently extracted for 309,757 trees in 604 census tracts. We used the average annual age- standardized rate of medication sales in Brussels for the period 2006 to 2014, calculated from reimbursement information on medication prescribed to adults (19-64 years of age). The medication sales data were provided by sex at the census tract level. Generalized log-linear models were used to investigate associations between the number of trees, the crown volume, tree structural variation, and medication sales. Models were run separately for mood disorder and cardiovascular medication and for men and women. All models were adjusted for indicators of area-level socioeconomic status. Results: Single-factor models showed that higher stem densities and higher crown volumes are both associated with lower medication sales, but opposing associations emerged in multifactor models. Higher crown volume [an increase by one interquartile range (IQR) of 1.4 * [10.sup.4] [m.sup.3]/ha] was associated with 34% lower mood disorder medication sales [women, [beta] = - 0.341 (95% CI: -0.379, -0.303); men, [beta] = - 0.340 (95% CI: -0.378, -0.303)] and with 21-25% lower cardiovascular medication sales [women, [beta] = - 0.214 (95% CI: -0.246, - 0.182); men, [beta] = - 0.252 (95% CI: -0.285, -0.219)]. Conversely, a higher stem density (an increase by one IQR of 21.8trees/ha) was associated with 28-32% higher mood disorder medication sales [women, [beta] = 0.322 (95% CI: 0.284, 0.361); men, [beta] = 0.281 (95% CI: 0.243, 0.319)] and with 20-24% higher cardiovascular medication sales [women, [beta] = 0.202 (95% CI: 0.169, 0.236); men, [beta] = 0.240 (95% CI: 0.206, 0.273)]. Discussion: We found a trade-off between the number of trees and the crown volumes of those trees for human health benefits in an urban environment. Our results demonstrate that conserving large trees in urban environments may not only support conservation of biodiversity but also human health. https://doi.org/10.1289/EHP9924, Introduction Urban green spaces, and especially urban trees, have been associated with numerous human health benefits through a number of regulating and cultural ecosystem services (Aerts et al. 2021; Chen [...]

Published
2022
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11. Long-Term Exposure to Low-Level PM2.5 and Mortality: Investigation of Heterogeneity by Harmonizing Analyses in Large Cohort Studies in Canada, United States, and Europe.

Author

Jie Chen, Braun, Danielle, Christidis, Tanya, Cork, Michael, Rodopoulou, Sophia, Samoli, Evangelia, Stafoggia, Massimo, Wolf, Kathrin, Xiao Wu, Weiran Yuchi, Andersen, Zorana J., Atkinson, Richard, Bauwelinck, Mariska, de Hoogh, Kees, Janssen, Nicole A. H., Katsouyanni, Klea, Klompmaker, Jochem O., Kristoffersen, Doris Tove, Youn-Hee Lim, and Oftedal, Bente

Subjects
MORTALITY risk factors, PARTICULATE matter, AERODYNAMICS, RELATIVE medical risk, CONFIDENCE intervals, NOSOLOGY, META-analysis, RISK assessment, SOCIAL classes, DESCRIPTIVE statistics, DATA analysis software, ENVIRONMENTAL exposure, LONGITUDINAL method, PROPORTIONAL hazards models, MEDICARE, POISSON distribution
Abstract

BACKGROUND: Studies across the globe generally reported increased mortality risks associated with particulate matter with aerodynamic diameter ≤2.5 μm (PM2.5) exposure with large heterogeneity in the magnitude of reported associations and the shape of concentration-response functions (CRFs). We aimed to evaluate the impact of key study design factors (including confounders, applied exposure model, population age, and outcome definition) on PM2.5 effect estimates by harmonizing analyses on three previously published large studies in Canada [Mortality-Air Pollution Associations in Low Exposure Environments (MAPLE), 1991-2016], the United States (Medicare, 2000-2016), and Europe [Effects of Low-Level Air Pollution: A Study in Europe (ELAPSE), 2000-2016] as much as possible. METHODS: We harmonized the study populations to individuals 65+ years of age, applied the same satellite-derived PM2.5 exposure estimates, and selected the same sets of potential confounders and the same outcome. We evaluated whether differences in previously published effect estimates across cohorts were reduced after harmonization among these factors. Additional analyses were conducted to assess the influence of key design features on estimated risks, including adjusted covariates and exposure assessment method. A combined CRF was assessed with meta-analysis based on the extended shape-constrained health impact function (eSCHIF). RESULTS: More than 81 million participants were included, contributing 692 million person-years of follow-up. Hazard ratios and 95% confidence intervals (CIs) for all-cause mortality associated with a 5-μg/m³ increase in PM2.5 were 1.039 (1.032, 1.046) in MAPLE, 1.025 (1.021, 1.029) in Medicare, and 1.041 (1.014, 1.069) in ELAPSE. Applying a harmonized analytical approach marginally reduced difference in the observed associations across the three studies. Magnitude of the association was affected by the adjusted covariates, exposure assessment methodology, age of the population, and marginally by outcome definition. Shape of the CRFs differed across cohorts but generally showed associations down to the lowest observed PM2.5 levels. A common CRF suggested a monotonically increased risk down to the lowest exposure level. [ABSTRACT FROM AUTHOR]

Published
2023
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13. Additional file 1 of Association between exposure to multiple air pollutants, transportation noise and cause-specific mortality in adults in Switzerland

Author

Vienneau, Danielle, Stafoggia, Massimo, Rodopoulou, Sophia, Chen, Jie, Atkinson, Richard W., Bauwelinck, Mariska, Klompmaker, Jochem O., Oftedal, Bente, Andersen, Zorana J., Janssen, Nicole A. H., So, Rina, Lim, Youn-Hee, Flückiger, Benjamin, Ducret-Stich, Regina, Röösli, Martin, Probst-Hensch, Nicole, Künzli, Nino, Strak, Maciek, Samoli, Evangelia, de Hoogh, Kees, Brunekreef, Bert, and Hoek, Gerard

Abstract

Additional file 1: Table S1. Study population selection. Table S2. Exposure distributions. Table S3. Spearman correlations between exposures (top), and between exposures and neighbourhood socio-economic position (SEP) score (bottom). Table S4. Mean exposure by quintiles of neighbourhood socio-economic position. Table S5. Hazard ratios (95% confidence intervals) for single exposure associations between air pollution and noise exposures and mortality by cause, with increasing level of covariate adjustment in single exposure models. Table S6. Effect modification by sex, hazard ratios (95% confidence intervals) in two exposure models for associations with natural cause mortality (Model 3). Table S7. Non-mover analysis, hazard ratios (95% confidence intervals) in two exposure models for associations with natural cause mortality (Model 3).

Published
2023
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14. Causal modeling of the effects of fine particulate matter and nitrogen dioxide on natural-cause mortality within the ELAPSE project

Author

Wolf, Kathrin, primary, Rodopoulou, Sophia, additional, Chen, Jie, additional, Atkinson, Richard W, additional, Bauwelinck, Mariska, additional, Strak, Maciek, additional, Lim, Youn-Hee, additional, Oftedal, Bente, additional, Vienneau, Danielle, additional, Zhang, Jiawei, additional, Brunekreef, Bert, additional, Hoek, Gerard, additional, Stafoggia, Massimo, additional, and Samoli, Evangelia, additional

Published
2022
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16. Mortality and Morbidity Effects of Long-Term Exposure to Low-Level PM

Author

Brunekreef, Bert, Strak, Maciej, Chen, Jie, J Andersen, Zorana, Atkinson, Richard, Bauwelinck, Mariska, Bellander, Tom, Boutron, Marie-Christine, Brandt, Jørgen, Carey, Iain, Cesaroni, Giulia, Forastiere, Francesco, Fecht, Daniela, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, de Hoogh, Kees, Houthuijs, Danny, Hvidtfeldt, Ulla, Janssen, Nicole, Jørgensen, Jeanette, Katsouyanni, Klea, Ketzel, Matthias, Klompmaker, Jochem, Hjertager Krog, Norun, Liu, Shuo, Ljungman, Petter, Mehta, Amar, Nagel, Gabriele, Oftedal, Bente, Pershagen, Göran, Peters, Annette, Raaschou-Nielsen, Ole, Renzi, Matteo, Rodopoulou, Sophia, Samoli, Evi, Schwarze, Per, Sigsgaard, Torben, Stafoggia, Massimo, Vienneau, Danielle, Weinmayr, Gudrun, Wolf, Kathrin, and Hoek, Gerard

Subjects
Adult, Air Pollutants, Canada, Lung Neoplasms, Incidence, Nitrogen Dioxide, Coronary Disease, Environmental Exposure, Asthma, United States, Stroke, Pulmonary Disease, Chronic Obstructive, Zinc, Soot, Humans, Copper, Sulfur, Aged
Abstract

Epidemiological cohort studies have consistently found associations between long-term exposure to outdoor air pollution and a range of morbidity and mortality endpoints. Recent evaluations by the World Health Organization and the Global Burden of Disease study have suggested that these associations may be nonlinear and may persist at very low concentrations. Studies conducted in North America in particular have suggested that associations with mortality persisted at concentrations of particulate matter with an aerodynamic diameter of less than 2.5 μm (PMWe focused on analyses of health effects of air pollutants at low concentrations, defined as less than current European Union (EU) Limit Values, U.S. Environmental Protection Agency (U.S. EPA), National Ambient Air Quality Standards (NAAQS), and/or World Health Organization (WHO) Air Quality Guideline values for PMIn the pooled cohort, virtually all subjects in 2010 had PMLong-term exposure to PM

Published
2022

18. Long-term exposure to air pollution and mortality in a Danish nationwide administrative cohort study: Beyond mortality from cardiopulmonary disease and lung cancer

Author

So, Rina, primary, Andersen, Zorana J., additional, Chen, Jie, additional, Stafoggia, Massimo, additional, de Hoogh, Kees, additional, Katsouyanni, Klea, additional, Vienneau, Danielle, additional, Rodopoulou, Sophia, additional, Samoli, Evangelia, additional, Lim, Youn-Hee, additional, Jørgensen, Jeanette T., additional, Amini, Heresh, additional, Cole-Hunter, Tom, additional, Mahmood Taghavi Shahri, Seyed, additional, Maric, Matija, additional, Bergmann, Marie, additional, Liu, Shuo, additional, Azam, Shadi, additional, Loft, Steffen, additional, Westendorp, Rudi G.J., additional, Mortensen, Laust H., additional, Bauwelinck, Mariska, additional, Klompmaker, Jochem O., additional, Atkinson, Richard, additional, Janssen, Nicole A.H., additional, Oftedal, Bente, additional, Renzi, Matteo, additional, Forastiere, Francesco, additional, Strak, Maciek, additional, Thygesen, Lau C., additional, Brunekreef, Bert, additional, Hoek, Gerard, additional, and Mehta, Amar J., additional

Published
2022
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19. Greenspace exposure and children behavior: A systematic review

Author

Zare Sakhvidi, Mohammad Javad, primary, Knobel, Pablo, additional, Bauwelinck, Mariska, additional, de Keijzer, Carmen, additional, Boll, Lilian Marie, additional, Spano, Giuseppina, additional, Ubalde-Lopez, Monica, additional, Sanesi, Giovanni, additional, Mehrparvar, Amir Houshang, additional, Jacquemin, Bénédicte, additional, and Dadvand, Payam, additional

Published
2022
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21. Additional file 1 of Long-term exposure to residential greenness and neurodegenerative disease mortality among older adults: a 13-year follow-up cohort study

Author

Rodriguez-Loureiro, Lucía, Gadeyne, Sylvie, Bauwelinck, Mariska, Lefebvre, Wouter, Vanpoucke, Charlotte, and Casas, Lidia

Abstract

Additional file 1: Table S1. Detailed description of the environmental indicators. Five largest Belgian urban areas, 2001-2014. Table S2. Stepwise adjustment of the associations (HR) and 95% confidence intervals (95%CI) between one IQR increment (0.22) of residential surrounding greenness (buffer size 500-m) and neurodegenerative disease mortality. Five largest Belgian urban areas, 2001-2014. Table S3. Associations (HR) and 95%CI of the associations between surrounding greenness (buffer size 500-m) categorised into quintiles of exposure and neurodegenerative disease mortality. Five largest Belgian urban areas, 2001-2014. Table S4. Computed average causal mediation effects (ACME) i.e., indirect effects, average direct effects (ADE) and proportion mediated, and their corresponding 95% confidence intervals (95%CI) of the association between surrounding greenness and specific outcomes of neurodegenerative disease mortality, potentially mediated by 2010 air pollution (PM2.5 and NO2) concentrations. Five largest Belgian urban areas, 2001-2014. Table S5. Stratified analyses of the number of events and the associations (HR and 95%CI) between IQR increments of residential greenness and neurodegenerative disease mortality, by gender, educational level, and neighbourhood SEP. Five largest Belgian urban areas, 2001-2014. Table S6. Sensitivity analyses of the associations (HR and 95%CI) between IQR increments of surrounding greenness and neurodegenerative disease mortality on the full (imputed) population (n=1,134,502). Five largest Belgian urban areas, 2001-2014. Table S7. Sensitivity analyses of the associations (HR and 95%CI) between IQR increments of surrounding greenness (buffer size: 500-m) and neurodegenerative disease mortality on population groups. Five largest Belgian urban areas, 2001-2014. Figure S1. Directed Acyclic Graph (DAG) of the main association. Figure S2. Linearity of the exposure-response relationship using natural splines with three degrees of freedom. Note: Cox proportional hazard models stratified by age group and gender, including a frailty term for urban area, and adjusted by migrant background, household living arrangement, educational level, housing tenure, and area-level SEP. p-values resulting from the LRT comparing this model to the main model. Five largest Belgian urban areas, 2001-2014. Figure S3. Spearman correlations between residential surrounding greenness, ambient air pollution and area-level median net taxable income.

Published
2022
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24. Long-term exposure to fine particle elemental components and mortality in Europe: Results from six European administrative cohorts within the ELAPSE project

Author

Rodopoulou, Sophia, primary, Stafoggia, Massimo, additional, Chen, Jie, additional, de Hoogh, Kees, additional, Bauwelinck, Mariska, additional, Mehta, Amar J., additional, Klompmaker, Jochem O., additional, Oftedal, Bente, additional, Vienneau, Danielle, additional, Janssen, Nicole A.H., additional, Strak, Maciej, additional, Andersen, Zorana J., additional, Renzi, Matteo, additional, Cesaroni, Giulia, additional, Nordheim, Carl Fredrik, additional, Bekkevold, Terese, additional, Atkinson, Richard, additional, Forastiere, Francesco, additional, Katsouyanni, Klea, additional, Brunekreef, Bert, additional, Samoli, Evangelia, additional, and Hoek, Gerard, additional

Published
2022
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25. Variability in the association between long-term exposure to ambient air pollution and mortality by exposure assessment method and covariate adjustment: A census-based country-wide cohort study

Author

Bauwelinck, Mariska, primary, Chen, Jie, additional, de Hoogh, Kees, additional, Katsouyanni, Klea, additional, Rodopoulou, Sophia, additional, Samoli, Evangelia, additional, Andersen, Zorana J., additional, Atkinson, Richard, additional, Casas, Lidia, additional, Deboosere, Patrick, additional, Demoury, Claire, additional, Janssen, Nicole, additional, Klompmaker, Jochem O., additional, Lefebvre, Wouter, additional, Mehta, Amar Jayant, additional, Nawrot, Tim S., additional, Oftedal, Bente, additional, Renzi, Matteo, additional, Stafoggia, Massimo, additional, Strak, Maciek, additional, Vandenheede, Hadewijch, additional, Vanpoucke, Charlotte, additional, Van Nieuwenhuyse, An, additional, Vienneau, Danielle, additional, Brunekreef, Bert, additional, and Hoek, Gerard, additional

Published
2022
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26. Long term exposure to low level air pollution and mortality in eight European cohorts within the ELAPSE project: pooled analysis

Author

Strak, Maciej, primary, Weinmayr, Gudrun, additional, Rodopoulou, Sophia, additional, Chen, Jie, additional, de Hoogh, Kees, additional, Andersen, Zorana J, additional, Atkinson, Richard, additional, Bauwelinck, Mariska, additional, Bekkevold, Terese, additional, Bellander, Tom, additional, Boutron-Ruault, Marie-Christine, additional, Brandt, Jørgen, additional, Cesaroni, Giulia, additional, Concin, Hans, additional, Fecht, Daniela, additional, Forastiere, Francesco, additional, Gulliver, John, additional, Hertel, Ole, additional, Hoffmann, Barbara, additional, Hvidtfeldt, Ulla Arthur, additional, Janssen, Nicole A H, additional, Jöckel, Karl-Heinz, additional, Jørgensen, Jeanette T, additional, Ketzel, Matthias, additional, Klompmaker, Jochem O, additional, Lager, Anton, additional, Leander, Karin, additional, Liu, Shuo, additional, Ljungman, Petter, additional, Magnusson, Patrik K E, additional, Mehta, Amar J, additional, Nagel, Gabriele, additional, Oftedal, Bente, additional, Pershagen, Göran, additional, Peters, Annette, additional, Raaschou-Nielsen, Ole, additional, Renzi, Matteo, additional, Rizzuto, Debora, additional, van der Schouw, Yvonne T, additional, Schramm, Sara, additional, Severi, Gianluca, additional, Sigsgaard, Torben, additional, Sørensen, Mette, additional, Stafoggia, Massimo, additional, Tjønneland, Anne, additional, Verschuren, W M Monique, additional, Vienneau, Danielle, additional, Wolf, Kathrin, additional, Katsouyanni, Klea, additional, Brunekreef, Bert, additional, Hoek, Gerard, additional, and Samoli, Evangelia, additional

Published
2021
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27. Long-term exposure to low concentrations of air pollution and cause-specific mortality beyond cardiorespiratory disease: A Danish nationwide cohort study

Author

So, Rina, primary, Andersen, Zorana Jovanovic, additional, Stafoggia, Massimo, additional, Oftedal, Bente, additional, Atkinson, Richard, additional, Rodopoulou, Sophia, additional, Vienneau, Danielle, additional, Bauwelinck, Mariska, additional, Janssen, Nicole, additional, Hoek, Gerard, additional, Brunekreef, Bert, additional, and Mehta, Amar Jayant, additional

Published
2021
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28. Long-term exposure to ambient particulate matter components and mortality: results from six European administrative cohorts within the ELAPSE project

Author

Rodopoulou, Sophia, primary, Stafoggia, Massimo, additional, Samoli, Evangelia, additional, Bauwelinck, Mariska, additional, Vienneau, Danielle, additional, Oftedal, Bente, additional, Andersen, Zorana J., additional, Janssen, Nicole, additional, Katsouyanni, Klea, additional, Brunekreef, Bert, additional, Hoek, Gerard, additional, and ELAPSE Project Team, on behalf of the, additional

Published
2021
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30. Long‐term exposure to air pollution and liver cancer incidence in six European cohorts

Author

So, Rina, primary, Chen, Jie, additional, Mehta, Amar J., additional, Liu, Shuo, additional, Strak, Maciej, additional, Wolf, Kathrin, additional, Hvidtfeldt, Ulla A., additional, Rodopoulou, Sophia, additional, Stafoggia, Massimo, additional, Klompmaker, Jochem O., additional, Samoli, Evangelia, additional, Raaschou‐Nielsen, Ole, additional, Atkinson, Richard, additional, Bauwelinck, Mariska, additional, Bellander, Tom, additional, Boutron‐Ruault, Marie‐Christine, additional, Brandt, Jørgen, additional, Brunekreef, Bert, additional, Cesaroni, Giulia, additional, Concin, Hans, additional, Forastiere, Francesco, additional, Gils, Carla H., additional, Gulliver, John, additional, Hertel, Ole, additional, Hoffmann, Barbara, additional, Hoogh, Kees, additional, Janssen, Nicole, additional, Lim, Youn‐hee, additional, Westendorp, Rudi, additional, Jørgensen, Jeanette T., additional, Katsouyanni, Klea, additional, Ketzel, Matthias, additional, Lager, Anton, additional, Lang, Alois, additional, Ljungman, Petter L., additional, Magnusson, Patrik K.E., additional, Nagel, Gabriele, additional, Simonsen, Mette K., additional, Pershagen, Göran, additional, Peter, Raphael S., additional, Peters, Annette, additional, Renzi, Matteo, additional, Rizzuto, Debora, additional, Sigsgaard, Torben, additional, Vienneau, Danielle, additional, Weinmayr, Gudrun, additional, Severi, Gianluca, additional, Fecht, Daniela, additional, Tjønneland, Anne, additional, Leander, Karin, additional, Hoek, Gerard, additional, and Andersen, Zorana J., additional

Published
2021
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31. Long-term exposure to low-level air pollution and incidence of asthma: the ELAPSE project

Author

Liu, Shuo, primary, Jørgensen, Jeanette Therming, additional, Ljungman, Petter, additional, Pershagen, Göran, additional, Bellander, Tom, additional, Leander, Karin, additional, Magnusson, Patrik K.E., additional, Rizzuto, Debora, additional, Hvidtfeldt, Ulla A., additional, Raaschou-Nielsen, Ole, additional, Wolf, Kathrin, additional, Hoffmann, Barbara, additional, Brunekreef, Bert, additional, Strak, Maciej, additional, Chen, Jie, additional, Mehta, Amar, additional, Atkinson, Richard W., additional, Bauwelinck, Mariska, additional, Varraso, Raphaëlle, additional, Boutron-Ruault, Marie-Christine, additional, Brandt, Jørgen, additional, Cesaroni, Giulia, additional, Forastiere, Francesco, additional, Fecht, Daniela, additional, Gulliver, John, additional, Hertel, Ole, additional, de Hoogh, Kees, additional, Janssen, Nicole A.H., additional, Katsouyanni, Klea, additional, Ketzel, Matthias, additional, Klompmaker, Jochem O., additional, Nagel, Gabriele, additional, Oftedal, Bente, additional, Peters, Annette, additional, Tjønneland, Anne, additional, Rodopoulou, Sophia P., additional, Samoli, Evangelia, additional, Kristoffersen, Doris Tove, additional, Sigsgaard, Torben, additional, Stafoggia, Massimo, additional, Vienneau, Danielle, additional, Weinmayr, Gudrun, additional, Hoek, Gerard, additional, and Andersen, Zorana Jovanovic, additional

Published
2021
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32. Long term exposure to low level air pollution and mortality in eight European cohorts within the ELAPSE project: pooled analysis

Author

Strak, Maciej Weinmayr, Gudrun Rodopoulou, Sophia Chen, Jie and de Hoogh, Kees Andersen, Zorana J. Atkinson, Richard and Bauwelinck, Mariska Bekkevold, Terese Bellander, Tom and Boutron-Ruault, Marie-Christine Brandt, Jorgen Cesaroni, Giulia and Concin, Hans Fecht, Daniela Forastiere, Francesco and Gulliver, John Hertel, Ole Hoffmann, Barbara Hvidtfeldt, Ulla Arthur Janssen, Nicole A. H. Jockel, Karl-Heinz and Jorgensen, Jeanette Ketzel, Matthias Klompmaker, Jochem and Lager, Anton Leander, Karin Liu, Shuo Ljungman, Petter and Magnusson, Patrik K. E. Mehta, Amar J. Nagel, Gabriele and Oftedal, Bente Pershagen, Goran Peters, Annette and Raaschou-Nielsen, Ole Renzi, Matteo Rizzuto, Debora van der Schouw, Yvonne T. Schramm, Sara Severi, Gianluca Sigsgaard, Torben Sorensen, Mette Stafoggia, Massimo Tjonneland, Anne and Verschuren, W. M. Monique Vienneau, Danielle Wolf, Kathrin and Katsouyanni, Klea Brunekreef, Bert Hoek, Gerard Samoli, Evangelia

Abstract

OBJECTIVE To investigate the associations between air pollution and mortality, focusing on associations below current European Union, United States, and World Health Organization standards and guidelines. DESIGN Pooled analysis of eight cohorts. SETTING Multicentre project Effects of Low-Level Air Pollution: A Study in Europe (ELAPSE) in six European countries. PARTICIPANTS 325 367 adults from the general population recruited mostly in the 1990s or 2000s with detailed lifestyle data. Stratified Cox proportional hazard models were used to analyse the associations between air pollution and mortality. Western Europe-wide land use regression models were used to characterise residential air pollution concentrations of ambient fine particulate matter (PM2.5), nitrogen dioxide, ozone, and black carbon. MAIN OUTCOME MEASURES Deaths due to natural causes and cause specific mortality. RESULTS Of 325 367 adults followed-up for an average of 19.5 years, 47 131 deaths were observed. Higher exposure to PM2.5, nitrogen dioxide, and black carbon was associated with significantly increased risk of almost all outcomes. An increase of 5 mu g/m(3) in PM2.5 was associated with 13% (95% confidence interval 10.6% to 15.5%) increase in natural deaths; the corresponding figure for a 10 mu g/m(3) increase in nitrogen dioxide was 8.6% (7% to 10.2%). Associations with PM2.5, nitrogen dioxide, and black carbon remained significant at low concentrations. For participants with exposures below the US standard of 12 mu g/m(3) an increase of 5 mu g/m(3) in PM2.5 was associated with 29.6% (14% to 47.4%) increase in natural deaths. CONCLUSIONS Our study contributes to the evidence that outdoor air pollution is associated with mortality even at low pollution levels below the current European and North American standards and WHO guideline values. These findings are therefore an important contribution to the debate about revision of air quality limits, guidelines, and standards, and future assessments by the Global Burden of Disease.

Published
2021

33. Long-term exposure to low-level air pollution and incidence of chronic obstructive pulmonary disease: The ELAPSE project

Author

Liu, Shuo, Jørgensen, Jeanette Therming, Ljungman, Petter L.S., Pershagen, Göran, Bellander, Tom D., Leander, Karin, Magnusson, Patrik K.E., Rizzuto, Debora, Hvidtfeldt, Ulla Arthur, Raaschou-Nielsen, Ole, Wolf, Kathrin, Hoffmann, Barbara H., Brunekreef, Bert, Strak, Maciej, Chen, Jie, Mehta, Amar Jayant, Atkinson, Richard W., Bauwelinck, Mariska, Varraso, Raphäelle, Boutron-Ruault, Marie Christine, Brandt, Jørgen, Cesaroni, Giulia, Forastiere, Francesco, Fecht, Daniela, Gulliver, John, Hertel, Ole, de Hoogh, Kees, Janssen, Nicole A.H., Katsouyanni, Klea, Ketzel, Matthias, Klompmaker, Jochem O., Nagel, Gabriële C., Oftedal, Bente Margaret, Peters, Annette Michael, Tjønneland, Anne, Rodopoulou, Sophia P., Samoli, Evangelia, Bekkevold, Terese, Sigsgaard, Torben, Stafoggia, Massimo, Vienneau, D. S., Weinmayr, Gudrun, Hoek, Gerard, Andersen, Zorana, Jørgensen, Jeanette, Ljungman, Petter, Bellander, Tom, Magnusson, Patrik, Hvidtfeldt, Ulla, Hoffmann, Barbara, Mehta, Amar, Atkinson, Richard, Boutron-Ruault, Marie-Christine, Janssen, Nicole, Klompmaker, Jochem, Nagel, Gabriele, Oftedal, Bente, Peters, Annette, Rodopoulou, Sophia, Vienneau, Danielle, Centre de recherche en épidémiologie et santé des populations (CESP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Environmental Protection Agency, EPA: R-82811201 U.S. Environmental Protection Agency, EPA China Scholarship Council, CSC: 201806010406 Vetenskapsrådet, VR: 2017-00641 Karolinska Institutet, KI, Research described in this article was conducted under contract to the Health Effects Institute (HEI), an organization jointly funded by the United States Environmental Protection Agency (EPA) (Assistance Award No. R-82811201) and certain motor vehicle and engine manufacturers. The contents of this article do not necessarily reflect the views of HEI, or its sponsors, nor do they necessarily reflect the views and policies of the EPA or motor vehicle and engine manufacturers., This work was supported by the Health Effects Institute Research Agreement #4954-RFA14-3/16-5-3 and the China Scholarship Council No. 201806010406. SALT and TwinGene are sub-studies of The Swedish Twin Registry (STR) which is managed by Karolinska Institutet and receives additional funding through the Swedish Research Council under the grant no 2017-00641., Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), Interface Demography, Faculty of Economic and Social Sciences and Solvay Business School, and Sociology

Subjects
010504 meteorology & atmospheric sciences, [SDV]Life Sciences [q-bio], Air pollution, Low-level exposure, 010501 environmental sciences, medicine.disease_cause, 01 natural sciences, complex mixtures, Cohort Studies, Pulmonary Disease, Chronic Obstructive, Environmental Science(all), Environmental health, Air Pollution, medicine, Humans, Risk factor, Prospective cohort study, lcsh:Environmental sciences, 0105 earth and related environmental sciences, General Environmental Science, lcsh:GE1-350, Sweden, COPD, Air Pollutants, business.industry, Proportional hazards model, Incidence (epidemiology), Incidence, Hazard ratio, Environmental Exposure, medicine.disease, Confidence interval, 3. Good health, Europe, 13. Climate action, Particulate Matter, COPD incidence, business, Environmental Sciences
Abstract

Background: Air pollution has been suggested as a risk factor for chronic obstructive pulmonary disease (COPD), but evidence is sparse and inconsistent. Objectives: We examined the association between long-term exposure to low-level air pollution and COPD incidence. Methods: Within the ‘Effects of Low-Level Air Pollution: A Study in Europe’ (ELAPSE) study, we pooled data from three cohorts, from Denmark and Sweden, with information on COPD hospital discharge diagnoses. Hybrid land use regression models were used to estimate annual mean concentrations of particulate matter with a diameter < 2.5 µm (PM2.5), nitrogen dioxide (NO2), and black carbon (BC) in 2010 at participants’ baseline residential addresses, which were analysed in relation to COPD incidence using Cox proportional hazards models. Results: Of 98,058 participants, 4,928 developed COPD during 16.6 years mean follow-up. The adjusted hazard ratios (HRs) and 95% confidence intervals for associations with COPD incidence were 1.17 (1.06, 1.29) per 5 µg/m3 for PM2.5, 1.11 (1.06, 1.16) per 10 µg/m3 for NO2, and 1.11 (1.06, 1.15) per 0.5 10−5m−1 for BC. Associations persisted in subset participants with PM2.5 or NO2 levels below current EU and US limit values and WHO guidelines, with no evidence for a threshold. HRs for NO2 and BC remained unchanged in two-pollutant models with PM2.5, whereas the HR for PM2.5 was attenuated to unity with NO2 or BC. Conclusions: Long-term exposure to low-level air pollution is associated with the development of COPD, even below current EU and US limit values and possibly WHO guidelines. Traffic-related pollutants NO2 and BC may be the most relevant.

Published
2021

34. Long-term exposure to air pollution and liver cancer incidence in six European cohorts

Author

So, Rina Chen, Jie Mehta, Amar J. Liu, Shuo Strak, Maciej Wolf, Kathrin Hvidtfeldt, Ulla A. Rodopoulou, Sophia and Stafoggia, Massimo Klompmaker, Jochem O. Samoli, Evangelia and Raaschou-Nielsen, Ole Atkinson, Richard Bauwelinck, Mariska and Bellander, Tom Boutron-Ruault, Marie-Christine Brandt, Jorgen Brunekreef, Bert Cesaroni, Giulia Concin, Hans and Forastiere, Francesco van Gils, Carla H. Gulliver, John and Hertel, Ole Hoffmann, Barbara de Hoogh, Kees Janssen, Nicole and Lim, Youn-Hee Westendorp, Rudi Jorgensen, Jeanette T. and Katsouyanni, Klea Ketzel, Matthias Lager, Anton Lang, Alois and Ljungman, Petter L. Magnusson, Patrik K. E. Nagel, Gabriele and Simonsen, Mette K. Pershagen, Goran Peter, Raphael S. and Peters, Annette Renzi, Matteo Rizzuto, Debora Sigsgaard, Torben Vienneau, Danielle Weinmayr, Gudrun Severi, Gianluca and Fecht, Daniela Tjonneland, Anne Leander, Karin Hoek, Gerard Andersen, Zorana J.

Subjects
complex mixtures
Abstract

Particulate matter air pollution and diesel engine exhaust have been classified as carcinogenic for lung cancer, yet few studies have explored associations with liver cancer. We used six European adult cohorts which were recruited between 1985 and 2005, pooled within the “Effects of low-level air pollution: A study in Europe” (ELAPSE) project, and followed for the incidence of liver cancer until 2011 to 2015. The annual average exposure to nitrogen dioxide (NO2), particulate matter with diameter

Published
2021

35. Long-Term Exposure to Fine Particle Elemental Components and Natural and Cause-Specific Mortality—a Pooled Analysis of Eight European Cohorts within the ELAPSE Project

Author

Chen, Jie, primary, Rodopoulou, Sophia, additional, de Hoogh, Kees, additional, Strak, Maciej, additional, Andersen, Zorana J., additional, Atkinson, Richard, additional, Bauwelinck, Mariska, additional, Bellander, Tom, additional, Brandt, Jørgen, additional, Cesaroni, Giulia, additional, Concin, Hans, additional, Fecht, Daniela, additional, Forastiere, Francesco, additional, Gulliver, John, additional, Hertel, Ole, additional, Hoffmann, Barbara, additional, Hvidtfeldt, Ulla Arthur, additional, Janssen, Nicole A. H., additional, Jöckel, Karl-Heinz, additional, Jørgensen, Jeanette, additional, Katsouyanni, Klea, additional, Ketzel, Matthias, additional, Klompmaker, Jochem O., additional, Lager, Anton, additional, Leander, Karin, additional, Liu, Shuo, additional, Ljungman, Petter, additional, MacDonald, Conor J., additional, Magnusson, Patrik K.E., additional, Mehta, Amar, additional, Nagel, Gabriele, additional, Oftedal, Bente, additional, Pershagen, Göran, additional, Peters, Annette, additional, Raaschou-Nielsen, Ole, additional, Renzi, Matteo, additional, Rizzuto, Debora, additional, Samoli, Evangelia, additional, van der Schouw, Yvonne T., additional, Schramm, Sara, additional, Schwarze, Per, additional, Sigsgaard, Torben, additional, Sørensen, Mette, additional, Stafoggia, Massimo, additional, Tjønneland, Anne, additional, Vienneau, Danielle, additional, Weinmayr, Gudrun, additional, Wolf, Kathrin, additional, Brunekreef, Bert, additional, and Hoek, Gerard, additional

Published
2021
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36. Residing in urban areas with higher green space is associated with lower mortality risk: A census-based cohort study with ten years of follow-up

Author

Bauwelinck, Mariska, primary, Casas, Lidia, additional, Nawrot, Tim S., additional, Nemery, Benoit, additional, Trabelsi, Sonia, additional, Thomas, Isabelle, additional, Aerts, Raf, additional, Lefebvre, Wouter, additional, Vanpoucke, Charlotte, additional, Van Nieuwenhuyse, An, additional, Deboosere, Patrick, additional, and Vandenheede, Hadewijch, additional

Published
2021
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37. Residential Exposure to Urban Trees and Medication Sales for Mood Disorders and Cardiovascular Disease in Brussels, Belgium: An Ecological Study.

Author

Dengkai Chi, Aerts, Raf, Van Nieuwenhuyse, An, Bauwelinck, Mariska, Demoury, Claire, Plusquin, Michelle, Nawrot, Tim S., Casas, Lidia, and Somers, Ben

Subjects
CARDIOVASCULAR disease prevention, RATING of sales personnel, GEOGRAPHIC information systems, CONFIDENCE intervals, CENSUS, STRUCTURAL models, PLANTS, CARDIOVASCULAR agents, SEX distribution, SOCIOECONOMIC factors, AFFECTIVE disorders, DESCRIPTIVE statistics, METROPOLITAN areas, NATURE, DATA analysis software, ANTIPSYCHOTIC agents, POISSON distribution
Abstract

BACKGROUND: The available evidence for positive associations between urban trees and human health is mixed, partly because the assessment of exposure to trees is often imprecise because of, for instance, exclusion of trees in private areas and the lack of three-dimensional (3D) exposure indicators (e.g., crown volume). OBJECTIVES: We aimed to quantify all trees and relevant 3D structural traits in Brussels (Belgium) and to investigate associations between the number of trees, tree traits, and sales of medication commonly prescribed for mood disorders and cardiovascular disease. METHODS: We developed a workflow to automatically isolate all individual trees from airborne light detection and ranging (LiDAR) data collected in 2012. Trait data were subsequently extracted for 309,757 trees in 604 census tracts. We used the average annual age-standardized rate of medication sales in Brussels for the period 2006 to 2014, calculated from reimbursement information on medication prescribed to adults (19–64 years of age). The medication sales data were provided by sex at the census tract level. Generalized log-linear models were used to investigate associations between the number of trees, the crown volume, tree structural variation, and medication sales. Models were run separately for mood disorder and cardiovascular medication and for men and women. All models were adjusted for indicators of area-level socioeconomic status. RESULTS: Single-factor models showed that higher stem densities and higher crown volumes are both associated with lower medication sales, but opposing associations emerged in multifactor models. Higher crown volume [an increase by one interquartile range (IQR) of 1.4×104 m³/ha] was associated with 34% lower mood disorder medication sales [women, β= -0.341 (95% CI: -0.379, -0.303); men, β= -0.340 (95% CI: -0.378, -0.303)] and with 21–25% lower cardiovascular medication sales [women, β= -0.214 (95% CI: -0.246, -0.182); men, β= -0.252 (95% CI: -0.285, -0.219)]. Conversely, a higher stem density (an increase by one IQR of 21.8 trees/ha) was associated with 28–32% higher mood disorder medication sales [women, β=0.322 (95% CI: 0.284, 0.361); men, β=0.281 (95% CI: 0.243, 0.319)] and with 20–24% higher cardiovascular medication sales [women, β=0.202 (95% CI: 0.169, 0.236); men, β=0.240 (95% CI: 0.206, 0.273)]. DISCUSSION: We found a trade-off between the number of trees and the crown volumes of those trees for human health benefits in an urban environment. Our results demonstrate that conserving large trees in urban environments may not only support conservation of biodiversity but also human health. [ABSTRACT FROM AUTHOR]

Published
2022
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38. Modeling multi-level survival data in multi-center epidemiological cohort studies: Applications from the ELAPSE project

Author

Samoli, Evangelia, primary, Rodopoulou, Sophia, additional, Hvidtfeldt, Ulla A., additional, Wolf, Kathrin, additional, Stafoggia, Massimo, additional, Brunekreef, Bert, additional, Strak, Maciej, additional, Chen, Jie, additional, Andersen, Zorana J., additional, Atkinson, Richard, additional, Bauwelinck, Mariska, additional, Bellander, Tom, additional, Brandt, Jørgen, additional, Cesaroni, Giulia, additional, Forastiere, Francesco, additional, Fecht, Daniela, additional, Gulliver, John, additional, Hertel, Ole, additional, Hoffmann, Barbara, additional, de Hoogh, Kees, additional, Janssen, Nicole A.H., additional, Ketzel, Matthias, additional, Klompmaker, Jochem O., additional, Liu, Shuo, additional, Ljungman, Petter, additional, Nagel, Gabriele, additional, Oftedal, Bente, additional, Pershagen, Göran, additional, Peters, Annette, additional, Raaschou-Nielsen, Ole, additional, Renzi, Matteo, additional, Kristoffersen, Doris T., additional, Severi, Gianluca, additional, Sigsgaard, Torben, additional, Vienneau, Danielle, additional, Weinmayr, Gudrun, additional, Hoek, Gerard, additional, and Katsouyanni, Klea, additional

Published
2021
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40. Long-term exposure to fine particle elemental components and lung cancer incidence in the ELAPSE pooled cohort

Author

Hvidtfeldt, Ulla Arthur, primary, Chen, Jie, additional, Andersen, Zorana Jovanovic, additional, Atkinson, Richard, additional, Bauwelinck, Mariska, additional, Bellander, Tom, additional, Brandt, Jørgen, additional, Brunekreef, Bert, additional, Cesaroni, Giulia, additional, Concin, Hans, additional, Fecht, Daniela, additional, Forastiere, Francesco, additional, van Gils, Carla H., additional, Gulliver, John, additional, Hertel, Ole, additional, Hoek, Gerard, additional, Hoffmann, Barbara, additional, de Hoogh, Kees, additional, Janssen, Nicole, additional, Jørgensen, Jeanette Therming, additional, Katsouyanni, Klea, additional, Jöckel, Karl-Heinz, additional, Ketzel, Matthias, additional, Klompmaker, Jochem O., additional, Lang, Alois, additional, Leander, Karin, additional, Liu, Shuo, additional, Ljungman, Petter L.S., additional, Magnusson, Patrik K.E., additional, Mehta, Amar Jayant, additional, Nagel, Gabriele, additional, Oftedal, Bente, additional, Pershagen, Göran, additional, Peter, Raphael Simon, additional, Peters, Annette, additional, Renzi, Matteo, additional, Rizzuto, Debora, additional, Rodopoulou, Sophia, additional, Samoli, Evangelia, additional, Schwarze, Per Everhard, additional, Severi, Gianluca, additional, Sigsgaard, Torben, additional, Stafoggia, Massimo, additional, Strak, Maciej, additional, Vienneau, Danielle, additional, Weinmayr, Gudrun, additional, Wolf, Kathrin, additional, and Raaschou-Nielsen, Ole, additional

Published
2021
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41. Comparison of associations between mortality and air pollution exposure estimated with a hybrid, a land-use regression and a dispersion model

Author

Klompmaker, Jochem O., primary, Janssen, Nicole, additional, Andersen, Zorana J., additional, Atkinson, Richard, additional, Bauwelinck, Mariska, additional, Chen, Jie, additional, de Hoogh, Kees, additional, Houthuijs, Danny, additional, Katsouyanni, Klea, additional, Marra, Marten, additional, Oftedal, Bente, additional, Rodopoulou, Sophia, additional, Samoli, Evangelia, additional, Stafoggia, Massimo, additional, Strak, Maciej, additional, Swart, Wim, additional, Wesseling, Joost, additional, Vienneau, Danielle, additional, Brunekreef, Bert, additional, and Hoek, Gerard, additional

Published
2021
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42. Long-term low-level ambient air pollution exposure and risk of lung cancer – A pooled analysis of 7 European cohorts

Author

Hvidtfeldt, Ulla Arthur, primary, Severi, Gianluca, additional, Andersen, Zorana Jovanovic, additional, Atkinson, Richard, additional, Bauwelinck, Mariska, additional, Bellander, Tom, additional, Boutron-Ruault, Marie-Christine, additional, Brandt, Jørgen, additional, Brunekreef, Bert, additional, Cesaroni, Giulia, additional, Chen, Jie, additional, Concin, Hans, additional, Forastiere, Francesco, additional, van Gils, Carla H., additional, Gulliver, John, additional, Hertel, Ole, additional, Hoek, Gerard, additional, Hoffmann, Barbara, additional, de Hoogh, Kees, additional, Janssen, Nicole, additional, Jöckel, Karl-Heinz, additional, Jørgensen, Jeanette Therming, additional, Katsouyanni, Klea, additional, Ketzel, Matthias, additional, Klompmaker, Jochem O., additional, Krog, Norun Hjertager, additional, Lang, Alois, additional, Leander, Karin, additional, Liu, Shuo, additional, Ljungman, Petter L.S., additional, Magnusson, Patrik K.E., additional, Mehta, Amar Jayant, additional, Nagel, Gabriele, additional, Oftedal, Bente, additional, Pershagen, Göran, additional, Peter, Raphael Simon, additional, Peters, Annette, additional, Renzi, Matteo, additional, Rizzuto, Debora, additional, Rodopoulou, Sophia, additional, Samoli, Evangelia, additional, Schwarze, Per Everhard, additional, Sigsgaard, Torben, additional, Simonsen, Mette Kildevæld, additional, Stafoggia, Massimo, additional, Strak, Maciek, additional, Vienneau, Danielle, additional, Weinmayr, Gudrun, additional, Wolf, Kathrin, additional, Raaschou-Nielsen, Ole, additional, and Fecht, Daniela, additional

Published
2021
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43. Long-term exposure to low-level air pollution and incidence of asthma: the ELAPSE project

Author

Liu, Shuo, primary, Jørgensen, Jeanette Therming, additional, Ljungman, Petter, additional, Pershagen, Göran, additional, Bellander, Tom, additional, Leander, Karin, additional, Magnusson, Patrik K.E., additional, Rizzuto, Debora, additional, Hvidtfeldt, Ulla A., additional, Raaschou-Nielsen, Ole, additional, Wolf, Kathrin, additional, Hoffmann, Barbara, additional, Brunekreef, Bert, additional, Strak, Maciej, additional, Chen, Jie, additional, Mehta, Amar, additional, Atkinson, Richard W., additional, Bauwelinck, Mariska, additional, Varraso, Raphaëlle, additional, Boutron-Ruault, Marie-Christine, additional, Brandt, Jørgen, additional, Cesaroni, Giulia, additional, Forastiere, Francesco, additional, Fecht, Daniela, additional, Gulliver, John, additional, Hertel, Ole, additional, de Hoogh, Kees, additional, Janssen, Nicole A.H., additional, Katsouyanni, Klea, additional, Ketzel, Matthias, additional, Klompmaker, Jochem O., additional, Nagel, Gabriele, additional, Oftedal, Bente, additional, Peters, Annette, additional, Tjønneland, Anne, additional, Rodopoulou, Sophia P., additional, Samoli, Evangelia, additional, Kristoffersen, Doris Tove, additional, Sigsgaard, Torben, additional, Stafoggia, Massimo, additional, Vienneau, Danielle, additional, Weinmayr, Gudrun, additional, Hoek, Gerard, additional, and Andersen, Zorana Jovanovic, additional

Published
2020
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44. Residential urban greenspace and hypertension: A comparative study in two European cities

Author

Bauwelinck, Mariska, primary, Zijlema, Wilma L., additional, Bartoll, Xavier, additional, Vandenheede, Hadewijch, additional, Cirach, Marta, additional, Lefebvre, Wouter, additional, Vanpoucke, Charlotte, additional, Basagaña, Xavier, additional, Nieuwenhuijsen, Mark J., additional, Borrell, Carme, additional, Deboosere, Patrick, additional, and Dadvand, Payam, additional

Published
2020
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45. Development of Europe-Wide Models for Particle Elemental Composition Using Supervised Linear Regression and Random Forest

Author

Chen, Jie, primary, de Hoogh, Kees, additional, Gulliver, John, additional, Hoffmann, Barbara, additional, Hertel, Ole, additional, Ketzel, Matthias, additional, Weinmayr, Gudrun, additional, Bauwelinck, Mariska, additional, van Donkelaar, Aaron, additional, Hvidtfeldt, Ulla A., additional, Atkinson, Richard, additional, Janssen, Nicole A. H., additional, Martin, Randall V., additional, Samoli, Evangelia, additional, Andersen, Zorana J., additional, Oftedal, Bente M., additional, Stafoggia, Massimo, additional, Bellander, Tom, additional, Strak, Maciej, additional, Wolf, Kathrin, additional, Vienneau, Danielle, additional, Brunekreef, Bert, additional, and Hoek, Gerard, additional

Published
2020
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46. Residential green space and medication sales for childhood asthma: A longitudinal ecological study in Belgium

Author

Aerts, Raf, primary, Dujardin, Sebastien, additional, Nemery, Benoit, additional, Van Nieuwenhuyse, An, additional, Van Orshoven, Jos, additional, Aerts, Jean-Marie, additional, Somers, Ben, additional, Hendrickx, Marijke, additional, Bruffaerts, Nicolas, additional, Bauwelinck, Mariska, additional, Casas, Lidia, additional, Demoury, Claire, additional, Plusquin, Michelle, additional, and Nawrot, Tim S., additional

Published
2020
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47. Heat related mortality in the two largest Belgian urban areas: A time series analysis

Author

De Troeyer, Katrien, primary, Bauwelinck, Mariska, additional, Aerts, Raf, additional, Profer, Dimitrios, additional, Berckmans, Julie, additional, Delcloo, Andy, additional, Hamdi, Rafiq, additional, Van Schaeybroeck, Bert, additional, Hooyberghs, Hans, additional, Lauwaet, Dirk, additional, Demoury, Claire, additional, and Van Nieuwenhuyse, An, additional

Published
2020
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49. A comparison of linear regression, regularization, and machine learning algorithms to develop Europe-wide spatial models of fine particles and nitrogen dioxide

Author

Chen, Jie, primary, de Hoogh, Kees, additional, Gulliver, John, additional, Hoffmann, Barbara, additional, Hertel, Ole, additional, Ketzel, Matthias, additional, Bauwelinck, Mariska, additional, van Donkelaar, Aaron, additional, Hvidtfeldt, Ulla A., additional, Katsouyanni, Klea, additional, Janssen, Nicole A.H., additional, Martin, Randall V., additional, Samoli, Evangelia, additional, Schwartz, Per E., additional, Stafoggia, Massimo, additional, Bellander, Tom, additional, Strak, Maciek, additional, Wolf, Kathrin, additional, Vienneau, Danielle, additional, Vermeulen, Roel, additional, Brunekreef, Bert, additional, and Hoek, Gerard, additional

Published
2019
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50. Mortality and Morbidity Effects of Long-Term Exposure to Low-Level PM2.5, BC, NO2, and O3: An Analysis of European Cohorts in the ELAPSE Project.

Author

Brunekreef, Bert, Strak, Maciej, Jie Chen, Andersen, Zorana J., Atkinson, Richard, Bauwelinck, Mariska, Bellander, Tom, Boutron, Marie-Christine, Brandt, Jørgen, Carey, Iain, Cesaroni, Giulia, Forastiere, Francesco, Fecht, Daniela, Gulliver, John, Hertel, Ole, Hoffmann, Barbara, Hoogh, Kees de, Houthuijs, Danny, Hvidtfeldt, Ulla, and Janssen, Nicole

Published
2021

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