109 results on '"Beck, Elizabeth M."'
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2. Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M4Muscarinic Acetylcholine Receptor
3. Pd-Catalyzed C–H Bond Functionalization on the Indole and Pyrrole Nucleus
4. The synthesis and in vivo evaluation of [18F]PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH)
5. Pd-Catalyzed C–H Bond Functionalization on the Indole and Pyrrole Nucleus
6. Synthesis and Structure‐Activity Relationships of N ‐(4‐Benzamidino)‐Oxazolidinones: Potent and Selective Inhibitors of Kallikrein‐Related Peptidase 6
7. Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1
8. Synthesis and Structure‐Activity Relationships of N‐(4‐Benzamidino)‐Oxazolidinones: Potent and Selective Inhibitors of Kallikrein‐Related Peptidase 6.
9. Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation
10. Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain
11. Temporal changes in avian abundance in aspen-dominated boreal mixedwood forests of central Saskatchewan, Canada
12. Oxidative Pd(II)-catalyzed C-H bond amination to carbazole at ambient temperature
13. Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase
14. The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) Imaging
15. Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase
16. Effects of Oil Sands Process-Affected Water on Waterfowl
17. Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality
18. Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors
19. Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation.
20. Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain.
21. Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors
22. Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design
23. Biased representation of disturbance rates in the roadside sampling frame in boreal forests: implications for monitoring design
24. Evidence of low toxicity of oil sands process-affected water to birds invites re-evaluation of avian protection strategies
25. Mild aerobic oxidative palladium (ll) catalyzed C-H bond functionalization: Regioselective and switchable C-H alkenylation and annulation of pyrroles
26. The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) Imaging.
27. Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality.
28. Chapter 8. C–H Activation Approaches to Molecules
29. Health of Domestic Mallards (Anas platyrhynchos domestica) Following Exposure to Oil Sands Process-Affected Water
30. Design and Selection Parameters to Accelerate the Discovery of Novel Central Nervous System Positron Emission Tomography (PET) Ligands and Their Application in the Development of a Novel Phosphodiesterase 2A PET Ligand
31. Evidence of low toxicity of oil sands processaffected water to birds invites re-evaluation of avian protection strategies.
32. Chemical Synthesis of Aspidosperma Alkaloids Inspired by the Reverse of the Biosynthesis of the Rhazinilam Family of Natural Products
33. ChemInform Abstract: Chiral Sulfinamide/Achiral Sulfonic Acid Cocatalyzed Enantioselective Protonation of Enol Silanes.
34. Chiral Sulfinamide/Achiral Sulfonic Acid Cocatalyzed Enantioselective Protonation of Enol Silanes
35. ChemInform Abstract: Pd-Catalyzed C-H Bond Functionalization on the Indole and Pyrrole Nucleus
36. ChemInform Abstract: Oxidative Pd(II)-Catalyzed C-H Bond Amination to Carbazole at Ambient Temperature.
37. Oxidative Pd(II)-Catalyzed C−H Bond Amination to Carbazole at Ambient Temperature
38. Synthesis of Rhazinicine by a Metal‐Catalyzed CH Bond Functionalization Strategy
39. Bend-ribbon forming γ-peptides
40. Discovery of a Series of Efficient,Centrally EfficaciousBACE1 Inhibitors through Structure-Based Drug Design.
41. Mild Aerobic Oxidative Palladium (II) Catalyzed C—H Bond Functionalization: Regioselective and Switchable C—H Alkenylation and Annulation of Pyrroles.
42. Mild Aerobic Oxidative Palladium (II) Catalyzed C−H Bond Functionalization: Regioselective and Switchable C−H Alkenylation and Annulation of Pyrroles
43. Expedient Diels—Alder Assembly of 4-Aryl-4-phenylsulfonyl Cyclohexanones.
44. Expedient Diels–Alder assembly of 4-aryl-4-phenylsulfonyl cyclohexanones
45. Designand Selection Parameters to Accelerate theDiscovery of Novel Central Nervous System Positron Emission Tomography(PET) Ligands and Their Application in the Development of a NovelPhosphodiesterase 2A PET Ligand.
46. Chiral Sulfinamide/Achiral Sulfonic Acid Cocatalyzed Enantioselective Protonation of Enol Silanes
47. Mild Aerobic Oxidative Palladium (II) Catalyzed C—H Bond Functionalization: Regioselective and Switchable C—H Alkenylation and Annulation of Pyrroles.
48. ChemInform Abstract: Pd-Catalyzed C-H Bond Functionalization on the Indole and Pyrrole Nucleus.
49. The synthesis and in vivo evaluation of [18F]PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH)
50. Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M 4 Muscarinic Acetylcholine Receptor.
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