42 results on '"Becq, Frederic"'
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2. Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity
3. Modulation of cellular membrane properties as a potential therapeutic strategy to counter lipointoxication in obstructive pulmonary diseases
4. Function, pharmacological correction and maturation of new Indian CFTR gene mutations
5. A new 9-alkyladenine-cyclic methylglyoxal diadduct activates wt- and F508del-cystic fibrosis transmembrane conductance regulator (CFTR) in vitro and in vivo
6. ANO1 contributes to Angiotensin-II-activated Ca2 +-dependent Cl− current in human atrial fibroblasts
7. Bronchorelaxation of the human bronchi by CFTR activators
8. Effect of VX-770 (Ivacaftor) and OAG on Ca2 + influx and CFTR activity in G551D and F508del-CFTR expressing cells
9. CFTR: Effect of ICL2 and ICL4 amino acids in close spatial proximity on the current properties of the channel
10. Pharmacological therapy for cystic fibrosis: From bench to bedside
11. C Terminus of Nucleotide Binding Domain 1 Contains Critical Features for Cystic Fibrosis Transmembrane Conductance Regulator Trafficking and Activation
12. Phosphatase Inhibitors Activate Normal and Defective CFTR Chloride Channels
13. Anti-inflammatory effect of miglustat in bronchial epithelial cells
14. Stimulation of salivary secretion in vivo by CFTR potentiators in Cftr+/+ and Cftr−/− mice
15. Guanabenz, an α 2-selective adrenergic agonist, activates Ca 2+-dependent chloride currents in cystic fibrosis human airway epithelial cells
16. NHE-RF1 protein rescues [DELTA]F508-CFTR function
17. MPB-07 Reduces the Inflammatory Response to Pseudomonas aeruginosa in Cystic Fibrosis Bronchial Cells
18. Determination of CFTR chloride channel activity and pharmacology using radiotracer flux methods
19. A Cystic Fibrosis Tracheal Gland Cell Line, CF-KM4: Correction by Adenovirus-Mediated CFTR Gene Transfer
20. Focus on TRP channels in cystic fibrosis
21. Phospholipase C controls chloride-dependent short-circuit current in human bronchial epithelial cells.
22. Development of Automated Patch Clamp Technique to Investigate CFTR Chloride Channel Function
23. Properties of CFTR activated by the xanthine derivative X-33 in human airway Calu-3 cells
24. Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07
25. An expeditious access to 5-pyrimidinol derivatives from cyclic methylglyoxal diadducts, formation of argpyrimidines under physiological conditions and discovery of new CFTR inhibitors
26. ANO1 contributes to Angiotensin-II-activated Ca2+-dependent Cl− current in human atrial fibroblasts
27. C-Branched Iminosugars: α-Glucosidase Inhibition by Enantiomers of isoDMDP, isoDGDP, and isoDAB–l-isoDMDP Compared to Miglitol and Miglustat
28. 4-C-Me-DAB and 4-C-Me-LAB—enantiomeric alkyl-branched pyrrolidine iminosugars—are specific and potent α-glucosidase inhibitors; acetone as the sole protecting group
29. Cystic fibrosis and diabetes: isoLAB and isoDAB, enantiomeric carbon-branched pyrrolidine iminosugars
30. Rescue of Functional F508del Cystic Fibrosis Transmembrane Conductance Regulator by Vasoactive Intestinal Peptide in the Human Nasal Epithelial Cell Line JME/CF15
31. Angiotensin Ii Activates Calcium-Dependent Cl- Channels In Human Cardiac Fibroblasts
32. Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the α-glucosidase inhibitor miglustat
33. On the Discovery and Development of CFTR Chloride Channel Activators
34. Benzo(c)quinolizinium drugs inhibit degradation of ΔF508-CFTR cytoplasmic domain
35. Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07
36. Activation of G551D CFTR channel with MPB-91: regulation by ATPase activity and phosphorylation
37. Interleukin-1β Secretion Is Impaired by Inhibitors of the Atp Binding Cassette Transporter, ABC1
38. Anti-inflammatory effect of miglustat in bronchial epithelial cells
39. Benzo(c)quinolizinium drugs inhibit degradation of <f>Δ</f>F508-CFTR cytoplasmic domain
40. ANO1 contributes to Angiotensin-II-activated Ca2+-dependent Cl− current in human atrial fibroblasts.
41. 4-C-Me-DAB and 4-C-Me-LAB - enantiomeric alkyl-branched pyrrolidine iminosugars - are specific and potent α-glucosidase inhibitors; acetone as the sole protecting group.
42. Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the alpha-glucosidase inhibitor miglustat.
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