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Recent trends in higher education indicate a steady increase in the number of adult and non-traditional learners returning to complete college degrees. Though higher education can provide numerous economic and career enhancement opportunities, adult learners experience several challenges when they return to college. The purpose of this qualitative research study was to gather and analyze data from employees from companies in the Midwest to determine the challenges and motivations of adult learners who plan to return to higher education. The results highlight that it is important for institutions of higher education to collaborate with employers to identify ways to modify their student recruitment methods to attract more adult student learners and identify supportive resources to help them complete their degrees successfully.

Background: Neurodegenerative diseases have been one of the major concerns for human health. Genetic and environmental factors are believed to be responsible for neuronal diseases such as Parkinson's disease, Alzheimer's disease, and Huntington's disease. It is difficult to restore normal nervous function after neurodegeneration; hence, prevention could be the best strategy against these diseases. Ayurved medicines such as Suvarna Bhasma (SB) have enormous potential to treat these neurological diseases. Aim: The aim of this study is to examine the protective effect of SB against rotenone-induced Parkinson's-like model in zebrafish. Materials and methods: In this study, we induced Parkinson's-like disease model in zebrafish by inducing it with rotenone (7 μg/L). We examined the behavioural, proteomics and dopamine alterations of rotenone induced zebrafish of SB pre-treated group as compared to the control group. Results: The behavioural experiments showed that due to rotenone exposure, Parkinson's-like behavioural abnormality was induced in zebrafish. However, because of SB treatment, this behavioural abnormality was reduced. The proteomics study of zebrafish brains clearly showed that the SB-treated group was not significantly affected due to rotenone exposure. However, in the SB non-treated group, expression of nine proteins that are linked to Parkinson's disease (gene name: sncgb, ywhae1, ywhah, uchl1, ywhaba, psma6a, ywhabl, ywhaqb, and ywhabb) were differentially expressed after rotenone exposure. Finally, prevention of dopamine alteration in SB-treated fish brains confirmed the protective action of SB against rotenone-induced Parkinson's-like model in zebrafish. Conclusions: This study finds that Suvarna Bhasma has neuroprotective effects against Parkinson's-like disease model.

Bimetallic nanostructures can exhibit significant broadening of Mie resonances compared to monometallic nanoparticles. Here, we study these materials using Electron Energy Loss Spectroscopy at a single particle level. This technique is immensely effective to probe direct structure-property correlation of nanoparticles. We are thus able to confirm the broadening of Mie resonances at a single particle level. This effect is analyzed in the context of emergence of a new dielectric constant that originates from metallic interfaces. We employ Coronado-Schatz corrections to the usual dielectric constants of the constituent metals to quantitatively simulate these materials. The resultant materials thus exhibit optical cross-sections that are 38.5 % and 4.2 % of the gold and silver nanoparticle optical cross-section at 2.5 eV and 3.45 eV, respectively. A strong agreement between theory and experiment is observed. We also confirmed the effectiveness of our approach for nanoparticles with different morphologies as well as different compositional ratios. Our study suggests an effective strategy to regulate the dielectric properties of bimetallic nanostructures through interface engineering.

Measurement(s) Bone microstructure and quality Technology Type(s) High-resolution imaging technology Factor Type(s) Osseointegration Sample Characteristic - Organism Oryctolagus cuniculus Sample Characteristic - Environment Sterile Environment Sample Characteristic - Location India

Abstract Background There is a continuous research in the area of biomimetic coatings on the titanium (Ti) implant surfaces for improved survival and long-term successful outcomes in the field of dentistry and orthopedics. In-vitro approaches are ideal systems for studying cell-material interactions without complexity and interference observed in in-vivo models. Purpose The present study was undertaken to evaluate the osteoblast characteristics and function on Ti substrates coated with the novel composite coating of ceramic apatite-wollastonite (AW) and polymer chitosan. Materials and methods Ti substrate coated with composite AW-Chitosan was synthesized, using electrophoretic deposition. MG-63 cells were seeded onto the coated substrates and cellular morphology and growth was assessed using Scanning Electron Microscopy (SEM) and Laser Scanning Microscopy (LSM). Osteocalcin expression of the seeded cells was assessed by FITC tagging and LSM analysis. Alizarin Red S staining and Confocal LSM (CSLM) analysis was used to study the in-vitro mineralization on the titanium samples. Results The AW-Chitosan coating on Ti samples by electrophoretic deposition exerted significant positive influence on cell proliferation, growth and mineralization as compared to uncoated titanium samples. Scanning electron microscopy and laser confocal microscopy experiments revealed that the coating was non-toxic to cells, enhanced adhesion and proliferation of MG-63 cells. Increased functional activity was observed by increased production of bone-specific protein osteocalcin and mineralized calcium through day 7 and 14. Conclusions The present study underscores that optimal inorganic-organic phase nanocomposite crack-free coating created on Ti by simple, cost-effective electrophoretic deposition technique may have osteoconductive potential and may have wide application in the field of implantology. Graphical abstract

Guided by Social Cognitive Career Theory, this study investigated the future perceptions of Hong Kong female university students. Fifty-eight students completed a semi-structured questionnaire to better understand their beliefs, hopes, and visions about their future. The thematic analysis performed yielded 10 major future life themes in the participants' responses: (a) work, (b) family, (c) roles and responsibilities, (d) romantic relationships, (e) values, (f) living situation, (g) quality of life, (h) status of education, (i) personal interests and hobbies, (j) finance, and (k) friendship. Findings from this study provide novel information on Hong Kong women's future perceptions that may help career counsellors when constructing client goals and tasks aimed at exploring and fulfilling their future perceptions.