223 results on '"Bellinzoni, Marco"'
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2. Actinobacteria challenge the paradigm : A unique protein architecture for a well-known, central metabolic complex
3. Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: Molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response
4. Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features.
5. Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts
6. Novel mechanistic insights into physiological signaling pathways mediated by mycobacterial Ser/Thr protein kinases
7. New substrates and interactors of the mycobacterial Serine/Threonine protein kinase PknG identified by a tailored interactomic approach
8. Energy Metabolism | 2-Oxoglutarate Dehydrogenase Complex
9. Structural Study of a New MbtI-Inhibitor Complex: Towards an Optimized Model for Structure-Based Drug Discovery
10. Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis
11. Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG
12. High resolution cryo-EM and crystallographic snapshots of the large actinobacterial 2-oxoglutarate dehydrogenase: an all-in-one fusion with unique properties
13. Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c
14. Characteristics of the GlnH and GlnX Signal Transduction Proteins Controlling PknG-Mediated Phosphorylation of OdhI and 2-Oxoglutarate Dehydrogenase Activity in Corynebacterium glutamicum
15. 5-(4-Nitrophenyl)furan-2-carboxylic Acid
16. The Antibacterial Type VII Secretion System of Bacillus subtilis: Structure and Interactions of the Pseudokinase YukC/EssB
17. Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase
18. 3-Keto-5-aminohexanoate Cleavage Enzyme: A COMMON FOLD FOR AN UNCOMMON CLAISEN-TYPE CONDENSATION
19. Functional Plasticity and Allosteric Regulation of α-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism
20. The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase‐like conformation
21. Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: Molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response
22. A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG
23. Mycobacterial Ser/Thr protein kinases and phosphatases: Physiological roles and therapeutic potential
24. Structural plasticity and distinct drug-binding modes of LfrR, a mycobacterial efflux pump regulator
25. Insights into the Catalytic Mechanism of PPM Ser/Thr Phosphatases from the Atomic Resolution Structures of a Mycobacterial Enzyme
26. A TPR scaffold couples signal detection to OdhI phosphorylation in metabolic control by the protein kinase PknG
27. GarA is an essential regulator of metabolism in Mycobacterium tuberculosis
28. Tolerance of the archaeal Sac7d scaffold protein to alternative library designs: characterization of anti-immunoglobulin G Affitins
29. The Multidrug Transporters Belonging to Major Facilitator Superfamily (MFS) in Mycobacterium tuberculosis
30. Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response
31. Selective Inhibition of 2-Oxoglutarate and 2-Oxoadipate Dehydrogenases by the Phosphonate Analogs of Their 2-Oxo Acid Substrates
32. Actinobacteria challenge the paradigm: a unique protein architecture for a well-known central metabolic complex
33. Structure-Based Drug Design for Tuberculosis: Challenges Still Ahead
34. Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design
35. Central role and structure of the membrane pseudokinase YukC in the antibacterial Bacillus subtilis Type VIIb Secretion System
36. Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance
37. Glutamine amidotransferase activity of NAD + synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain
38. Conserved autophosphorylation pattern in activation loops and juxtamembrane regions of Mycobacterium tuberculosis Ser/Thr protein kinases
39. Regulation of glutamate metabolism by protein kinases in mycobacteria
40. Techniques and Applications: The heterologous expression of Mycobacterium tuberculosis genes is an uphill road
41. New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents
42. Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling
43. Novel mechanistic insights into physiological signaling pathways mediated by mycobacterial Ser/Thr protein kinases
44. Heterologous expression, purification, and enzymatic activity of Mycobacterium tuberculosis NAD + synthetase
45. 2-Oxoglutarate Dehydrogenase Complex
46. Bacterial Metabolism under FHA Control
47. A novel role of malonyl-ACP in lipid homeostasis
48. PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis
49. Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosisSalicylate Synthase (MbtI) for Drug Design
50. The crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformation
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