353 results on '"Belluti, Federica"'
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2. Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold
3. Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy
4. Targeting neuronal calcium channels and GSK3β for Alzheimer’s disease with naturally-inspired Diels-Alder adducts
5. Naturally Inspired Coumarin Derivatives in Alzheimer's Disease Drug Discovery: Latest Advances and Current Challenges.
6. Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer
7. Improved eradication efficacy of a combination of newly identified antimicrobial agents in C. albicans and S. aureus mixed-species biofilm
8. Multifaceted activity of polyciclic MDR revertant agents in drug-resistant leukemic cells: Role of the spacer
9. Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment
10. Polycyclic maleimide-based derivatives as first dual modulators of neuronal calcium channels and GSK-3β for Alzheimer's disease treatment
11. Identification of chalcone-based antileishmanial agents targeting trypanothione reductase
12. Drifting of heme-coordinating group in imidazolylmethylxanthones leading to improved selective inhibition of CYP11B1
13. Coumarin derivatives as potential antitumor agents: Growth inhibition, apoptosis induction and multidrug resistance reverting activity
14. Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment
15. Chitosan nanoparticles for lipophilic anticancer drug delivery: Development, characterization and in vitro studies on HT29 cancer cells
16. Targeting the Multifaceted Neurotoxicity of Alzheimer's Diseaseby Tailored Functionalisation of the Curcumin Scaffold
17. Design, synthesis and biological profile of new inhibitors of multidrug resistance associated proteins carrying a polycyclic scaffold
18. Hitting drug-resistant malaria infection with triazole-linked flavonoid–chloroquine hybrid compounds
19. Interplay Between Endocannabinoid System and Neurodegeneration: Focus on Polypharmacology
20. Fluorinated benzophenone derivatives: Balanced multipotent agents for Alzheimer's disease
21. Natural-like Chalcones with Antitumor Activity on Human MG63 Osteosarcoma Cells
22. 2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents
23. Modulation of Amyloid β-Induced Microglia Activation and Neuronal Cell Death by Curcumin and Analogues
24. Multi-target strategy to address Alzheimer’s disease: Design, synthesis and biological evaluation of new tacrine-based dimers
25. Benzophenone-based derivatives: A novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation
26. Design, synthesis and anticancer activities of stilbene-coumarin hybrid compounds: Identification of novel proapoptotic agents
27. Flavonoid-Inspired Vascular Disrupting Agents: Exploring Flavone-8-Acetic Acid and Derivatives in the New Century
28. New Coumarin Derivatives as Cholinergic and Cannabinoid System Modulators
29. Tackling Alzheimer’s Disease with Existing Drugs: A Promising Strategy for Bypassing Obstacles
30. Novel dual D3R/GSK-3β modulators: an innovative multitarget strategy for bipolar disorder
31. Cholinesterase inhibitors: SAR and enzyme inhibitory activity of 3-[ ω-(benzylmethylamino)alkoxy]xanthen-9-ones
32. Reconsidering Aromatase for Breast Cancer Treatment: New Roles for an Old Target
33. New derivatives of xanthenone-4-acetic acid: Synthesis, pharmacological profile and effect on TNF-α and NO production by human immune cells
34. In vitro evaluation of newly developed chalcone analogues in human cancer cells
35. Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson’s Disease
36. Curcumin-1,2,3-Triazole Conjugation for Targeting the Cancer Apoptosis Machinery
37. Front Cover: Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation (ChemMedChem 11/2020)
38. Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation
39. 1,4-Dihydropyridine derivatives as calcium channel modulators: the role of 3-methoxy-flavone moiety
40. Cardiovascular hybrid drugs: new benzazepinone derivatives as bradycardic agents endowed with selective β1-Non-competitive antagonism
41. Targeting the Bacterial Membrane with a New Polycyclic Privileged Structure: A Powerful Tool To Face Staphylococcus aureus Infections
42. Benzophenones as xanthone-open model CYP11B1 inhibitors potentially useful for promoting wound healing
43. Identification of a new tamoxifen-xanthene hybrid as pro-apoptotic anticancer agent
44. Polycyclic Maleimide-based Scaffold as New Privileged Structure for Navigating the Cannabinoid System Opportunities
45. Functionalization of the Chalcone Scaffold for the Discovery of Novel Lead Compounds Targeting Fungal Infections
46. Prenylated Curcumin Analogues as Multipotent Tools To Tackle Alzheimer’s Disease
47. Cardiovascular Profile of Xanthone-Based 1,4 Dihydropyridines Bearing a Lidoflazine Pharmacophore Fragment
48. Exploiting the Chalcone Scaffold to Develop Multifunctional Agents for Alzheimer’s Disease
49. Dual BACE-1/GSK-3β Inhibitors to Combat Alzheimer's Disease: A Focused Review
50. Development of a Focused Library of Triazole‐Linked Privileged‐Structure‐Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections
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