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Your search keyword '"Belozerov, Konstantin E."' showing total 8 results
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8 results on '"Belozerov, Konstantin E."'

1. Defining criteria for disease activity states in systemic juvenile idiopathic arthritis based on the systemic Juvenile Arthritis Disease Activity Score

Author

Rosina, Silvia, primary, Rebollo‐Gimenez, Ana I., additional, Tarantola, Letizia, additional, Pistorio, Angela, additional, Vyzhga, Yulia, additional, El Miedany, Yasser, additional, Lotfy, Hala M., additional, Abu‐Shady, Hend, additional, Eissa, Mervat, additional, Osman, Naglaa S., additional, Hassan, Waleed, additional, Mahgoub, Marwa Y., additional, Fouad, Nermeen A., additional, Mosa, Doaa M., additional, Adel, Yasmin, additional, Mohamed, Sheren E. M., additional, Radwan, Ahmed R., additional, Abu‐Zaid, Mohamed H., additional, Tabra, Samar A. A., additional, Shalaby, Radwa H., additional, Nasef, Samah I., additional, Khubchandani, Raju, additional, Khan, Archana, additional, Maldar, Naziya P., additional, Ozen, Seza, additional, Bayindir, Yagmur, additional, Alsuweiti, Motasem, additional, Alzyoud, Raed, additional, Almaaitah, Hiba, additional, Vilaiyuk, Soamarat, additional, Lerkvaleekul, Butsabong, additional, Alexeeva, Ekaterina, additional, Dvoryakovskaya, Tatyana, additional, Kriulin, Ivan, additional, Bracaglia, Claudia, additional, Pardeo, Manuela, additional, De Benedetti, Fabrizio, additional, Licciardi, Francesco, additional, Montin, Davide, additional, Robasto, Francesca, additional, Minoia, Francesca, additional, Filocamo, Giovanni, additional, Rossano, Martina, additional, Simonini, Gabriele, additional, Marrani, Edoardo, additional, Abu‐Rumeleih, Sarah, additional, Kostik, Mikhail M., additional, Belozerov, Konstantin E., additional, Pal, Priyankar, additional, Bathia, Jigna N., additional, Katsicas, María M., additional, Villarreal, Giselle, additional, Marino, Achille, additional, Costi, Stefania, additional, Sztajnbok, Flavio, additional, Silva, Rodrigo M., additional, Maggio, Maria C., additional, El‐Ghoneimy, Dalia H., additional, El Owaidy, Rasha, additional, Civino, Adele, additional, Diomeda, Federico, additional, Al‐Mayouf, Sulaiman M., additional, Al‐Sofyani, Fuad, additional, Dāvidsone, Zane, additional, Patrone, Elisa, additional, Saad‐Magalhães, Claudia, additional, Consolaro, Alessandro, additional, and Ravelli, Angelo, additional

Published
2024
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3. Determination of Risk Factors for Severe Life-Threatening Course of Multisystem Inflammatory Syndrome Associated with COVID-19 in Children

Author

Avrusin, Ilia S., primary, Abramova, Natalia N., additional, Belozerov, Konstantin E., additional, Kondratiev, Gleb V., additional, Bregel, Liudmila V., additional, Efremova, Olesya S., additional, Vilnits, Alla A., additional, Konstantinova, Julia E., additional, Isupova, Eugenia A., additional, Kornishina, Tatiana L., additional, Masalova, Vera V., additional, Felker, Eugeniy Yu., additional, Kalashnikova, Olga V., additional, Chasnyk, Vyacheslav G., additional, Aleksandrovich, Yuriy S., additional, and Kostik, Mikhail M., additional

Published
2023
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4. Using HScore for Evaluation of Hemophagocytosis in Multisystem Inflammatory Syndrome Associated with COVID-19 in Children.

Author

Avrusin, Ilia S., Abramova, Natalia N., Belozerov, Konstantin E., Bregel, Liudmila V., Efremova, Olesya S., Vilnits, Alla A., Konstantinova, Julia E., Isupova, Eugenia A., Kornishina, Tatiana L., Masalova, Vera V., Kalashnikova, Olga V., Chasnyk, Vyacheslav G., Aleksandrovich, Yuriy S., Ivanov, Dmitri O., and Kostik, Mikhail M.

Subjects
MULTISYSTEM inflammatory syndrome, BLOOD sedimentation, MULTISYSTEM inflammatory syndrome in children, ASPIRIN, COVID-19, HAND-foot syndrome, MYELOFIBROSIS
Abstract

Hemophagocytic syndrome is a key point in the pathogenesis of severe forms of multisystem inflammatory syndrome associated with COVID-19 in children (MIS-C). The factors associated with hemophagocytosis in patients with MIS-C were assessed in the present study of 94 boys and 64 girls ranging in age from 4 months to 17 years, each of whose HScore was calculated. In accordance with a previous analysis, patients with HScore ≤ 91 (n = 79) and HScore > 91 (n = 79) were compared. Patients with HScore > 91 had a higher frequency of symptoms such as cervical lymphadenopathy, dry cracked lips, bright mucous, erythema/swelling of hands and feet, peeling of fingers, edematous syndrome, hepatomegaly, splenomegaly, and hypotension/shock. They also had a higher erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and D-dimer levels, and a tendency to anemia, thrombocytopenia, and hypofibrinogenemia. They more often needed acetylsalicylic acid and biological treatment and were admitted to ICU in 70.9% of cases. Conclusion: The following signs of severe MIS-C were associated with HScore > 91: myocardial involvement, pericarditis, hypotension/shock, and ICU admission. [ABSTRACT FROM AUTHOR]

Published
2024
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5. The predictors of severe course of multisystem inflammatory syndrome associated with the new coronavirus infection COVID-19 in children: results of a retrospective-prospective multicenter study

Author

Avrusin, Ilia S., primary, Abramova, Natalia N., additional, Belozerov, Konstantin E., additional, Efremova, Olesya S., additional, Bregel, Lyudmila V., additional, Kondratiev, Gleb V., additional, Dondurey, Elena A., additional, Vilnitz, Alla A., additional, Konstantinova, Yulia E., additional, Burtseva, Tatiana E., additional, Vinnikova, Ekaterina I., additional, Isupova, Evgeniya A., additional, Kornishina, Tatiana L., additional, Masalova, Vera V., additional, Redkina, Maria V., additional, Solodkova, Irina V., additional, Kalashnikova, Olga V., additional, Chasnyk, Vyacheslav G., additional, Alexandrovich, Yuri S., additional, and Kostik, Mikhail M., additional

Published
2023
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6. COVID-19 Associated Vasculitis Confirmed by the Tissues RT-PCR: A Case Series Report

Author

Belozerov, Konstantin E., primary, Avrusin, Ilia S., additional, Andaryanova, Lyubov I., additional, Guseva, Anna M., additional, Shogenova, Zaira S., additional, Belanovich, Irina N., additional, Lobacheva, Anna V., additional, Kornishina, Tatiana L., additional, Isupova, Eugenia A., additional, Masalova, Vera V., additional, Kalashnikova, Olga V., additional, Nokhrin, Andrey V., additional, Panova, Tatyana F., additional, Dutova, Yulia P., additional, Myshkovskaya, Svetlana L., additional, Kostyunin, Kirill Y., additional, Komissarov, Andrey B., additional, Chasnyk, Vyacheslav G., additional, Bregel, Liudmila V., additional, and Kostik, Mikhail M., additional

Published
2023
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7. Heart Involvement in Multisystem Inflammatory Syndrome, Associated With COVID-19 in Children: The Retrospective Multicenter Cohort Data

Author

Kostik, Mikhail M., primary, Bregel, Liudmila V., additional, Avrusin, Ilia S., additional, Efremova, Olesya S., additional, Belozerov, Konstantin E., additional, Dondurei, Elena A., additional, Kornishina, Tatiana L., additional, Isupova, Eugenia A., additional, Abramova, Natalia N., additional, Felker, Eugeniy Yu, additional, Masalova, Vera V., additional, Santimov, Andrey V., additional, Kozlov, Yuri A., additional, Barakin, Alexander O., additional, Snegireva, Ludmila S., additional, Konstantinova, Julia, additional, Vilnits, Alla A., additional, Bekhtereva, Maria K., additional, Argunova, Vera M., additional, Matyunova, Alla E., additional, Sleptsova, Polina A., additional, Burtseva, Tatyana E., additional, Shprakh, Vladimir V., additional, Boyko, Tatyana V., additional, Kalashnikova, Olga V., additional, and Chasnyk, Vyacheslav G., additional

Published
2022
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8. Initial Respiratory System Involvement in Juvenile Idiopathic Arthritis with Systemic Onset Is a Marker of Interstitial Lung Disease: The Results of Retrospective Cohort Study Analysis.

Author

Belozerov KE, Isupova EA, Solomatina NM, Gaidar EV, Kaneva MA, Chikova IA, Kalashnikova O, Kuznetsova AA, Ivanov DO, and Kostik MM

Abstract

Background: Pulmonary involvement in systemic juvenile idiopathic arthritis (SJIA) is a rare but dangerous complication. The main risk factors are already known, such as macrophage activation syndrome, a refractory course of systemic juvenile arthritis, infusion reaction to interleukin 1 and/or interleukin 6 blockers, trisomy 21, and eosinophilia. However, information about respiratory system involvement (RSI) at the onset of SJIA is scarce. Our study aimed to evaluate the specific features of children with SJIA with RSI and their outcomes. Methods: In a single-center retrospective cohort study, we compared the information from the medical records of 200 children with SJIA according to ILAR criteria or SJIA-like disease (probable/possible SJIA) with and without signs of RSI (dyspnea, shortness of breath, pleurisy, acute respiratory distress syndrome, and interstitial lung disease (ILD)) at the disease onset and evaluated their outcomes (remission, development of chronic ILD, clubbing, and pulmonary arterial hypertension). Results: A quarter (25%) of the SJIA patients had signs of the RSI at onset and they more often had rash; hepato- and splenomegaly; heart (pericarditis, myocarditis), central nervous system, and kidney involvement; hemorrhagic syndrome; macrophage activation syndrome (MAS, 44.4% vs. 9.0%, p = 0.0000001); and, rarely, arthritis with fewer active joints, compared to patients without RSI. Five patients (10% from the group having RSI at the onset of SJIA and 2.5% from the whole SJIA cohort) developed fibrosing ILD. All of them had a severe relapsed/chronic course of MAS; 80% of them had a tocilizumab infusion reaction and further switched to canakinumab. Unfortunately, one patient with Down's syndrome had gone. Conclusion: Patients with any signs of RSI at the onset of the SJIA are required to be closely monitored due to the high risk of the following fibrosing ILD development. They required prompt control of MAS, monitoring eosinophilia, and routine checks of night oxygen saturation for the prevention/early detection of chronic ILD.

Published
2024
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