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1. Immunocompromised-Associated Pediatric Acute Respiratory Distress Syndrome: Experience From the 2016/2017 Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Prospective Cohort Study*

Author

Gertz, Shira J., Bhalla, Anoopindar, Chima, Ranjit S., Emeriaud, Guillaume, Fitzgerald, Julie C., Hsing, Deyin D., Jeyapalan, Asumthia S., Pike, Francis, Sallee, Colin J., Thomas, Neal J., Yehya, Nadir, Rowan, Courtney M., Sforza, Jesica, Poterala, Rossana, Fernandez, Analia, Avila Vera, Antonio, Orqueda, Daniel, Agueda Vidal, Nilda, Rosemary, Deheza, Turon, Gonzalo, Monjes, Cecilia, Fernando Espanol, Segundo, Siaba Serrate, Alejandro, Iolster, Thomas, Torres, Silvio, Cinquegrani, Karina, Jose Montes, Maria, Capocasa, Patricia, Ferreyra, Marcela, Castellani, Pablo, Giampieri, Martin, Pedraza, Claudia, Martin Landry, Luis, Althabe, Maria, Vanesa Fortini, Yanina, Botta, Priscila, Paziencia, Fernando, Erickson, Simon, Barr, Samantha, Shea, Sara, Butt, Warwick, Delzoppo, Carmel, Pintimalla, Alyssa, Martinez Leon, Alejandro Fabio, Guzman Rivera, Gustavo Alfredo, Jouvet, Philippe, Emeriaud, Guillaume, Dumitrascu, Mariana, Ellen French, Mary, Caro, Daniel, Castillo, I, Andres, E., Cruces Romero, Pablo, Medina, Tania, Pavez Madrid, Paula, Cortez, Ambar, Alvear, Jimena, Acuna, Carlos, Diaz, Franco, Jose Nunez, Maria, Wegner Araya, Adriana, Godoy Mundaca, Loreto, Chen, Yang, Perez Lozano, German, Pardo Carrero, Rosalba, Lopez Alarcon, Yurika Paola, Mazzillo Vega, Liliana, Maria Izquierdo, Ledys, Piñeres Olave, Byron Enrique, Zuluaga Orrego, Cesar, Quinonez Lopez, Deyanira, Vasquez Hoyos, Pablo, Vavrina, Martin, Zurek, Jiri, Campos-Miño, Santiago, Yerovi, Rocio, Bridier, Armelle, Payen, Valerie, Milesi, Christophe, Bourgoin, Pierre, Travert, Brendan, Genuini, Mathieu, Starck, Julie, Maria, Matthieu, Guichoux, Julie, Baudin, Florent, Briassoulis, George, Ilia, Stavroula, Di Nardo, Matteo, Camporesi, Anna, Chiusolo, Fabrizio, Shime, Nobuaki, Ohshimo, Shinichiro, Kida, Yoshiko, Kyo, Michihito, Tabata, Yuichi, Fong Tang, Swee, Wern Tai, Chian, See Lum, Lucy Chai, Elghuwael, Ismail, Jimenez Rivera, Nestor Javier, Jarillo Quijada, Alberto E, Kneyber, Martin, Dijkstra, Sandra, Beca, John, Sherring, Claire, Miriam, Rea, Vargas G, Sonia I, Vasquez Miranda, Daniel, Ramirez Cortez, Grimaldo, Tantalean, Jose, Pagowska-Klimek, Izabela, Gil Escobar, Carlos, Sousa Moniz, Marta, Camilo, Cristina, Hazwani, Tarek, Aldairi, Nedaa, Al Amoudi, Ahmed, Alahmadti, Ahmad, Taylor, Ryan, Mendizabal, Mikel, Goni Orayen, Concepcion, Lopez Fernandez, Yolanda, Ramon Valle, Juan, Martinez, Lidia, Pilar Orive, Javier, Brezmes, Marta, Lopez-Herce, Jesus, Parrilla, Julio, Gaboli, Mirella, Gonzalez Gomez, Jose Manuel, Morales Martinez, Antonio, Alapont, Vicent Modesto I, Sanchez Diaz, Juan Ignacio, Llorente de la Fuente, Ana M., Palanca Arias, Daniel, Madurga Revilla, Paula, Martinez de Azagra, Amelia, Garcia Gonzalez, Maria, Arjona Villanueva, David, Garcia Casas, Paula, Brio Sanagustin, Sonia, Pons Odena, Marti, Medina, Alberto, Onate Vergara, Eider, Rodriguez Campoy, Patricia, Reyes Dominguez, Susana, Dursun, Oguz, Atike Ongun, Ebru, Kamit Can, Fulya, Berna Anil, Ayse, Baines, Paul, Walsh, Laura, Jones, Dawn, Sadasivam, Kalaimaran, Mildner, Reinout, Plunkett, Adrian, Lillie, Jon, Tibby, Shane, Wellman, Paul, Belfield, Holly, Brierley, Joe, Dominguez, Troy E., Abaleke, Eugenia, Feinstein, Yael, Deep, Akash, Sundararajan, Santosh, Oruganti, Siva, Silvestre, Catarina, Weitz, James, Sheward, Victoria, Macrae, Duncan, Aramburo, Angela, Fortune, Peter-Marc, Subramanian, Gayathri, Jennings, Claire, Dwarakanathan, Buvana, Inwald, David, Feather, Calandra, Agbeko, Rachel, Lawton-Woodhall, Angela, McIntyre, Karen, Sykes, Kim, Pappachan, Jon, Gale, Helen, Mellish, Christie, McCorkell, Jenni, Torero, Luis, Nofziger, Ryan, Latifi, Samir, Anthony, Heather, Sanders, Ron, Hefley, Glenda, Virk, Manpreet, Jaimon, Nancy, Maddux, Aline B., Mourani, Peter M., Ralston, Kimberly, Sierra, Yamila, Khemani, Robinder, Newth, Christopher, Bhalla, Anoopindar, Kwok, Jeni, Morzov, Rica, Mahapatra, Sidharth, Truemper, Edward, Kustka, Lucinda, Nett, Sholeen T., Singleton, Marcy, Dean Jarvis, J., Yehya, Nadir, Napolitano, Natalie, Murphy, Marie, Ronan, Laurie, Morgan, Ryan, Kubis, Sherri, Broden, Elizabeth, Willson, Douglas, Henderson, Grace, Gedeit, Rainer, Murkowski, Kathy, Woods, Katherine, Kasch, Mary, Han, Yong Y, Affolter, Jeremy T, Tieves, Kelly S, Hughes-Schalk, Amber, Chima, Ranjit S., Krallman, Kelli, Stoneman, Erin, Benken, Laura, Yunger, Toni, Schneider, James, Sweberg, Todd, Kessel, Aaron, Carroll, Christopher L., Santanelli, James, Ackerman, Kate G, Cullimore, Melissa, Rowan, Courtney, Bales, Melissa, Keith Dockery, W., Jafari-Namin, Shirin, Barry, Dana, Jane’t, Keary, Alibrahim, Omar, Patankar, Nikhil, Qiao, Haiping, Gertz, Shira, Su, Felice, Haileselassie, Bereketeab, Song, Hanqiu, Bysani, Kris, Monjure, Tracey, Beltramo, Fernando, Totapally, Balagangadhar, Govantes, Beatriz, Coates, Bria, Wellisch, Lawren, Allen, Kiona, Shukla, Avani, Thomas, Neal J., Spear, Debbie, Shein, Steven L., Gertz, Shira, Parker, Margaret M., Sloniewsky, Daniel, Allen, Christine, Harrell, Amy, Pinto, Neethi, Kniola, Allison, Rodgers, Chiara, Cvijanovich, Natalie, Typpo, Katri, Kelley, Connor, King, Caroline, Sapru, Anil, Ratiu, Anna, Ashtari, Neda, Sikora, Lindsay, Jeyapalan, Asumthia S., Coronado-Munoz, Alvaro, Flori, Heidi, Dahmer, Mary K., Jayachandran, Chaandini, Hume, Janet, Nerheim, Dan, Smith, Rebecca, Spaeder, Michael, Adu-Darko, Michelle, Smith, Lincoln, Hartmann, Silvia, Sullivan, Erin, Merritt, Courtney, Al-Subu, Awni, Blom, Andrea, Lin, John C., Spinella, Philip, Hsing, Deyin D., Pon, Steve, Brian Estil, Jim, Gautam, Richa, Giuliano, John S., Jr, and Tala, Joana

Published
2024
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3. Noninvasive Ventilation for Pediatric Acute Respiratory Distress Syndrome: Experience From the 2016/2017 Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Prospective Cohort Study*

Author

Emeriaud, Guillaume, Pons-Òdena, Marti, Bhalla, Anoopindar K., Shein, Steven L., Killien, Elizabeth Y., Modesto i Alapont, Vicent, Rowan, Courtney, Baudin, Florent, Lin, John C., Grégoire, Gabrielle, Napolitano, Natalie, Mayordomo-Colunga, Juan, Diaz, Franco, Cruces, Pablo, Medina, Alberto, Smith, Lincoln, Khemani, Robinder G., Sforza, Jesica, Poterala, Rossana, Fernandez, Analia, Avila Vera, Antonio, Orqueda, Daniel, Agueda Vidal, Nilda, Rosemary, Deheza, Turon, Gonzalo, Monjes, Cecilia, Espanol, Segundo Fernando, Serrate, Alejandro Siaba, Iolster, Thomas, Torres, Silvio, Cinquegrani, Karina, Jose Montes, Maria, Capocasa, Patricia, Ferreyra, Marcela, Castellani, Pablo, Giampieri, Martin, Pedraza, Claudia, Landry, Luis Martin, Althabe, Maria, Fortini, Yanina Vanesa, Botta, Priscila, Paziencia, Fernando, Erickson, Simon, Barr, Samantha, Shea, Sara, Butt, Warwick, Delzoppo, Carmel, Pintimalla, Alyssa, Leon, Alejandro Fabio Martinez, Rivera, Gustavo Alfredo Guzman, Jouvet, Philippe, Emeriaud, Guillaume, Dumitrascu, Mariana, Ellen French, Mary, Caro I, Daniel, Castillo, Andres E., Romero, Pablo Cruces, Medina, Tania, Madrid, Paula Pavez, Cortez, Ambar, Alvear, Jimena, Acuna, Carlos, Diaz, Franco, Nunez, Maria Jose, Araya, Adriana Wegner, Mundaca, Loreto Godoy, Chen, Yang, Lozano, German Perez, Carrero, Rosalba Pardo, Alarcon, Yurika Paola Lopez, Vega, Liliana Mazzillo, Izquierdo, Ledys Maria, Olave, Byron Enrique Piñeres, Orrego, Cesar Zuluaga, Lopez, Deyanira Quinonez, Hoyos, Pablo Vasquez, Vavrina, Martin, Zurek, Jiri, Campos-Miño, Santiago, Yerovi, Rocio, Bridier, Armelle, Payen, Valerie, Milesi, Christophe, Bourgoin, Pierre, Travert, Brendan, Genuini, Mathieu, Starck, Julie, Maria, Matthieu, Guichoux, Julie, Baudin, Florent, Briassoulis, George, Ilia, Stavroula, Di Nardo, Matteo, Camporesi, Anna, Chiusolo, Fabrizio, Shime, Nobuaki, Ohshimo, Shinichiro, Kida, Yoshiko, Kyo, Michihito, Tabata, Yuichi, Tang, Swee Fong, Tai, Chian Wern, Lum, Lucy Chai See, Elghuwael, Ismail, Rivera, Nestor Javier Jimenez, Jarillo Quijada, Alberto E, Kneyber, Martin, Dijkstra, Sandra, Beca, John, Sherring, Claire, Rea, Miriam, Vargas G, Sonia I, Miranda, Daniel Vasquez, Cortez, Grimaldo Ramirez, Tantalean, Jose, Pagowska-Klimek, Izabela, Escobar, Carlos Gil, Moniz, Marta Sousa, Camilo, Cristina, Hazwani, Tarek, Aldairi, Nedaa, Al Amoudi, Ahmed, Alahmadti, Ahmad, Taylor, Ryan, Mendizabal, Mikel, Orayen, Concepcion Goni, Fernandez, Yolanda Lopez, Valle, Juan Ramon, Martinez, Lidia, Orive, Javier Pilar, Brezmes, Marta, Lopez-Herce, Jesus, Parrilla, Julio, Gaboli, Mirella, Gomez, Jose Manuel Gonzalez, Morales Martinez, Antonio, Alapont, Vicent Modesto I, Diaz, Juan Ignacio Sanchez, Llorente de la Fuente, Ana M., Palanca Arias, Daniel, Madurga Revilla, Paula, Martinez de Azagra, Amelia, Garcia Gonzalez, Maria, Arjona Villanueva, David, Garcia Casas, Paula, Brio Sanagustin, Sonia, Pons Odena, Marti, Medina, Alberto, Onate Vergara, Eider, Rodriguez Campoy, Patricia, Reyes Dominguez, Susana, Dursun, Oguz, Atike Ongun, Ebru, Kamit Can, Fulya, Berna Anil, Ayse, Baines, Paul, Walsh, Laura, Jones, Dawn, Sadasivam, Kalaimaran, Mildner, Reinout, Plunkett, Adrian, Lillie, Jon, Tibby, Shane, Wellman, Paul, Belfield, Holly, Brierley, Joe, Dominguez, Troy E., Abaleke, Eugenia, Feinstein, Yael, Deep, Akash, Sundararajan, Santosh, Oruganti, Siva, Silvestre, Catarina, Weitz, James, Sheward, Victoria, Macrae, Duncan, Aramburo, Angela, Fortune, Peter-Marc, Subramanian, Gayathri, Jennings, Claire, Dwarakanathan, Buvana, Inwald, David, Feather, Calandra, Agbeko, Rachel, Lawton-Woodhall, Angela, McIntyre, Karen, Sykes, Kim, Pappachan, Jon, Gale, Helen, Mellish, Christie, McCorkell, Jenni, Torero, Luis, Nofziger, Ryan, Latifi, Samir, Anthony, Heather, Sanders, Ron, Hefley, Glenda, Virk, Manpreet, Jaimon, Nancy, Maddux, Aline B., Mourani, Peter M., Ralston, Kimberly, Sierra, Yamila, Khemani, Robinder, Newth, Christopher, Bhalla, Anoopindar, Kwok, Jeni, Morzov, Rica, Mahapatra, Sidharth, Truemper, Edward, Kustka, Lucinda, Nett, Sholeen T., Singleton, Marcy, Dean Jarvis, J., Yehya, Nadir, Napolitano, Natalie, Murphy, Marie, Ronan, Laurie, Morgan, Ryan, Kubis, Sherri, Broden, Elizabeth, Willson, Douglas, Henderson, Grace, Gedeit, Rainer, Murkowski, Kathy, Woods, Katherine, Kasch, Mary, Han, Yong Y, Affolter, Jeremy T, Tieves, Kelly S, Hughes-Schalk, Amber, Chima, Ranjit S., Krallman, Kelli, Stoneman, Erin, Benken, Laura, Yunger, Toni, Schneider, James, Sweberg, Todd, Kessel, Aaron, Carroll, Christopher L., Santanelli, James, Ackerman, Kate G, Cullimore, Melissa, Rowan, Courtney, Bales, Melissa, Keith Dockery, W., Jafari-Namin, Shirin, Barry, Dana, Jane’t, Keary, Alibrahim, Omar, Patankar, Nikhil, Qiao, Haiping, Gertz, Shira, Su, Felice, Haileselassie, Bereketeab, Song, Hanqiu, Bysani, Kris, Monjure, Tracey, Beltramo, Fernando, Totapally, Balagangadhar, Govantes, Beatriz, Coates, Bria, Wellisch, Lawren, Allen, Kiona, Shukla, Avani, Thomas, Neal J., Spear, Debbie, Shein, Steven L., Gertz, Shira, Parker, Margaret M., Sloniewsky, Daniel, Allen, Christine, Harrell, Amy, Pinto, Neethi, Kniola, Allison, Rodgers, Chiara, Cvijanovich, Natalie, Typpo, Katri, Kelley, Connor, King, Caroline, Sapru, Anil, Ratiu, Anna, Ashtari, Neda, Sikora, Lindsay, Jeyapalan, Asumthia S., Coronado-Munoz, Alvaro, Flori, Heidi, Dahmer, Mary K., Jayachandran, Chaandini, Hume, Janet, Nerheim, Dan, Smith, Rebecca, Spaeder, Michael, Adu-Darko, Michelle, Smith, Lincoln, Hartmann, Silvia, Sullivan, Erin, Merritt, Courtney, Al-Subu, Awni, Blom, Andrea, Lin, John C., Spinella, Philip, Hsing, Deyin D., Pon, Steve, Brian Estil, Jim, Gautam, Richa, Giuliano, John S., Jr, and Tala, Joana

Published
2023
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4. Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study

Author

Khemani, Robinder G, Smith, Lincoln, Lopez-Fernandez, Yolanda M, Kwok, Jeni, Morzov, Rica, Klein, Margaret J, Yehya, Nadir, Willson, Douglas, Kneyber, Martin CJ, Lillie, Jon, Fernandez, Analia, Newth, Christopher JL, Jouvet, Philippe, Thomas, Neal J, Investigators, Pediatric Acute Respiratory Distress syndrome Incidence and Epidemiology, Abaleke, Eugenia, Ackerman, Kate G, Acuña, Carlos, Adu-Darko, Michelle, Affolter, Jeremy T, Agbeko, Rachel, Amoudi, Ahmed Al, Alahmadti, Ahmad, Aldairi, Nedaa, Alibrahim, Omar, Allen, Kiona, Allen, Christine, Al-Subu, Awni, Althabe, María, Alvear, Jimena, Anil, Ayse Berna, Anthony, Heather, Aramburo, Angela, Villanueva, David Arjona, Ashtari, Neda, Vera, Antonio Ávila, Baines, Paul, Bales, Melissa, Barr, Samantha, Barry, Dana, Baudin, Florent, Beca, John, Belfield, Holly, Beltramo, Fernando, Benken, Laura, Bhalla, Anoopindar, Blom, Andrea, Botta, Priscila, Bourgoin, Pierre, Brezmes, Marta, Briassoulis, George, Bridier, Armelle, Brierley, Joe, Sanagustin, Sonia Brio, Broden, Elizabeth, Butt, Warwick, Bysani, Kris, Camilo, Cristina, Camporesi, Anna, Campos-Miño, Santiago, Can, Fulya Kamit, Capocasa, Patricia, Caro, Daniel, Carroll, Christopher, Castellani, Pablo, Castillo, Andres E, Chen, Yang, Chima, Ranjit S, Chiusolo, Fabrizio, Cinquegrani, Karina, Coates, Bria, Coronado-Munoz, Alvaro, Cortéz, Ambar, Romero, Pablo Cruces, Cullimore, Melissa, Cvijanovich, Natalie, Dahmer, Mary K, Deep, Akash, Delzoppo, Carmel, Di Nardo, Matteo, Díaz, Franco, Dijkstra, Sandra, Dockery, W Keith, Dominguez, Troy E, Dumitrascu, Mariana, Dursun, Oguz, Dwarakanathan, Buvana, Elghuwael, Ismail, Emeriaud, Guillaume, Erickson, Simon, Español, Segundo Fernando, Estil, Jim Brian, Feather, Calandra, Feinstein, Yael, Fernández, Analía, Ferreyra, Marcela, Flori, Heidi, Fortini, Yanina Vanesa, Fortune, Peter-Marc, and French, Mary Ellen

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Pediatric, Lung, Clinical Research, 4.1 Discovery and preclinical testing of markers and technologies, Detection, screening and diagnosis, Respiratory, Good Health and Well Being, Acute Lung Injury, Age Factors, Area Under Curve, Cause of Death, Child, Child, Preschool, Combined Modality Therapy, Cross-Sectional Studies, Female, Hospital Mortality, Humans, Intensive Care Units, Pediatric, Internationality, Kaplan-Meier Estimate, Male, Prognosis, Prospective Studies, Respiratory Distress Syndrome, Severity of Illness Index, Sex Factors, Survival Analysis, United States, Pediatric Acute Respiratory Distress syndrome Incidence and Epidemiology (PARDIE) Investigators, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, Public Health and Health Services, Other Medical and Health Sciences, Cardiovascular medicine and haematology, Clinical sciences
Abstract

BackgroundPaediatric acute respiratory distress syndrome (PARDS) is associated with high mortality in children, but until recently no paediatric-specific diagnostic criteria existed. The Pediatric Acute Lung Injury Consensus Conference (PALICC) definition was developed to overcome limitations of the Berlin definition, which was designed and validated for adults. We aimed to determine the incidence and outcomes of children who meet the PALICC definition of PARDS.MethodsIn this international, prospective, cross-sectional, observational study, 145 paediatric intensive care units (PICUs) from 27 countries were recruited, and over a continuous 5 day period across 10 weeks all patients were screened for enrolment. Patients were included if they had a new diagnosis of PARDS that met PALICC criteria during the study week. Exclusion criteria included meeting PARDS criteria more than 24 h before screening, cyanotic heart disease, active perinatal lung disease, and preparation or recovery from a cardiac intervention. Data were collected on the PICU characteristics, patient demographics, and elements of PARDS (ie, PARDS risk factors, hypoxaemia severity metrics, type of ventilation), comorbidities, chest imaging, arterial blood gas measurements, and pulse oximetry. The primary outcome was PICU mortality. Secondary outcomes included 90 day mortality, duration of invasive mechanical and non-invasive ventilation, and cause of death.FindingsBetween May 9, 2016, and June 16, 2017, during the 10 study weeks, 23 280 patients were admitted to participating PICUs, of whom 744 (3·2%) were identified as having PARDS. 95% (708 of 744) of patients had complete data for analysis, with 17% (121 of 708; 95% CI 14-20) mortality, whereas only 32% (230 of 708) of patients met Berlin criteria with 27% (61 of 230) mortality. Based on hypoxaemia severity at PARDS diagnosis, mortality was similar among those who were non-invasively ventilated and with mild or moderate PARDS (10-15%), but higher for those with severe PARDS (33% [54 of 165; 95% CI 26-41]). 50% (80 of 160) of non-invasively ventilated patients with PARDS were subsequently intubated, with 25% (20 of 80; 95% CI 16-36) mortality. By use of PALICC PARDS definition, severity of PARDS at 6 h after initial diagnosis (area under the curve [AUC] 0·69, 95% CI 0·62-0·76) discriminates PICU mortality better than severity at PARDS diagnosis (AUC 0·64, 0·58-0·71), and outperforms Berlin severity groups at 6 h (0·64, 0·58-0·70; p=0·01).InterpretationThe PALICC definition identified more children as having PARDS than the Berlin definition, and PALICC PARDS severity groupings improved the stratification of mortality risk, particularly when applied 6 h after PARDS diagnosis. The PALICC PARDS framework should be considered for use in future epidemiological and therapeutic research among children with PARDS.FundingUniversity of Southern California Clinical Translational Science Institute, Sainte Justine Children's Hospital, University of Montreal, Canada, Réseau en Santé Respiratoire du Fonds de Recherche Quebec-Santé, and Children's Hospital Los Angeles, Department of Anesthesiology and Critical Care Medicine.

Published
2019

7. A Phase II randomized controlled trial for lung and diaphragm protective ventilation (Real-time Effort Driven VENTilator management)

Author

Khemani, Robinder G., Hotz, Justin C, Klein, Margaret J., Kwok, Jeni, Park, Caron, Lane, Christianne, Smith, Erin, Kohler, Kristen, Suresh, Anil, Bornstein, Dinnel, Elkunovich, Marsha, Ross, Patrick A., Deakers, Timothy, Beltramo, Fernando, Nelson, Lara, Shah, Shilpa, Bhalla, Anoopindar, Curley, Martha A.Q., and Newth, Christopher J.L.

Published
2020
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10. Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study

Author

Abaleke, Eugenia, Ackerman, Kate G, Acuña, Carlos, Adu-Darko, Michelle, Affolter, Jeremy T, Agbeko, Rachel, Al Amoudi, Ahmed, Alahmadti, Ahmad, Aldairi, Nedaa, Alibrahim, Omar, Allen, Kiona, Allen, Christine, Al-Subu, Awni, Althabe, María, Alvear, Jimena, Anil, Ayse Berna, Anthony, Heather, Aramburo, Angela, Arjona Villanueva, David, Ashtari, Neda, Ávila Vera, Antonio, Baines, Paul, Bales, Melissa, Barr, Samantha, Barry, Dana, Baudin, Florent, Beca, John, Belfield, Holly, Beltramo, Fernando, Benken, Laura, Bhalla, Anoopindar, Blom, Andrea, Botta, Priscila, Bourgoin, Pierre, Brezmes, Marta, Briassoulis, George, Bridier, Armelle, Brierley, Joe, Brio Sanagustin, Sonia, Broden, Elizabeth, Butt, Warwick, Bysani, Kris, Camilo, Cristina, Camporesi, Anna, Campos-Miño, Santiago, Can, Fulya Kamit, Capocasa, Patricia, Caro I, Daniel, Carroll, Christopher, Castellani, Pablo, Castillo, Andres E., Chen, Yang, Chima, Ranjit S., Chiusolo, Fabrizio, Cinquegrani, Karina, Coates, Bria, Coronado-Munoz, Alvaro, Cortéz, Ambar, Cruces Romero, Pablo, Cullimore, Melissa, Cvijanovich, Natalie, Dahmer, Mary K., Deep, Akash, Delzoppo, Carmel, Di Nardo, Matteo, Díaz, Franco, Dijkstra, Sandra, Dockery, W. Keith, Dominguez, Troy E., Dumitrascu, Mariana, Dursun, Oguz, Dwarakanathan, Buvana, Elghuwael, Ismail, Emeriaud, Guillaume, Erickson, Simon, Español, Segundo Fernando, Estil, Jim Brian, Feather, Calandra, Feinstein, Yael, Fernández, Analía, Ferreyra, Marcela, Flori, Heidi, Fortini, Yanina Vanesa, Fortune, Peter-Marc, French, Mary Ellen, Gaboli, Mirella, Gale, Helen, García Casas, Paula, García González, Maria, Gautam, Richa, Gedeit, Rainer, Genuini, Mathieu, Gertz, Shira, Giampieri, Martin, Gil Escobar, Carlos, Giuliano Jr, John S., Godoy Mundaca, Loreto, Goni Orayen, Concepción, Gonzalez Gomez, Jose Manuel, Govantes, Beatriz, Guichoux, Julie, Guzman Rivera, Gustavo Alfredo, Haileselassie, Bereketeab, Han, Yong Y, Harrell, Amy, Hartmann, Silvia, Hazwani, Tarek, Hefley, Glenda, Henderson, Grace, Hsing, Deyin D., Hughes-Schalk, Amber, Hume, Janet, Ilia, Stavroula, Inwald, David, Iolster, Thomas, Izquierdo, Ledys María, Jafari-Namin, Shirin, Jaimon, Nancy, Jarillo Quijada, Alberto E, Jarvis, J. Dean, Jayachandran, Chaandini, Jennings, Claire, Jeyapalan, Asumthia S., Jimenez Rivera, Nestor Javier, Jones, Dawn, Jouvet, Philippe, Kasch, Mary, Keary, Jane't, Kelley, Connor, Kessel, Aaron, Khemani, Robinder, Kida, Yoshiko, King, Caroline, Kneyber, Martin, Kniola, Allison, Krallman, Kelli, Kubis, Sherri, Kustka, Lucinda, Kwok, Jeni, Kyo, Michihito, Landry, Luis Martín, Latifi, Samir, Lawton-Woodhall, Angela, Lillie, Jon, Lin, John C., Llorente de la Fuente, Ana M., Lopez Alarcón, Yurika Paola, López Fernández, Yolanda, Lopez-Herce, Jesús, Lum, Lucy Chai See, Macrae, Duncan, Maddux, Aline B., Madurga Revilla, Paula, Mahapatra, Sidharth, Maria, Matthieu, Martínez, Lidia, Martinez de Azagra, Amelia, Martínez León, Alejandro Fabio, Mazzillo Vega, Liliana, McCorkell, Jenni, McIntyre, Karen, Medina, Tania, Medina, Alberto, Mellish, Christie, Mendizabal, Mikel, Merritt, Courtney, Mildner, Reinout, Milesi, Christophe, Modesto I Alapont, Vicent, Monjes, Cecilia, Monjure, Tracey, Montes, María José, Morales Martinez, Antonio, Morgan, Ryan, Morzov, Rica, Mourani, Peter M., Murkowski, Kathy, Murphy, Marie, Napolitano, Natalie, Nerheim, Dan, Nett, Sholeen T., Newth, Christopher, Nofziger, Ryan, Nunez, Maria Jose, Ohshimo, Shinichiro, Onate Vergara, Eider, Ongun, Ebru A, Orqueda, Daniel, Oruganti, Siva, Pagowska-Klimek, Izabela, Palanca Arias, Daniel, Pappachan, Jon, Pardo Carrero, Rosalba, Parker, Margaret M., Parrilla, Julio, Patankar, Nikhil, Pávez Madrid, Paula, Payen, Valerie, Paziencia, Fernando, Pedraza, Claudia, Perez Lozano, Germán, Pilar Orive, Javier, Piñeres Olave, Byron Enrique, Pintimalla, Alyssa, Pinto, Neethi, Plunkett, Adrian, Pon, Steve, Pons Odena, Marti, Poterala, Rossana, Qiao, Haiping, Quiñonez Lopez, Deyanira, Ralston, Kimberly, Ramirez Cortez, Grimaldo, Ratiu, Anna, Rea, Miriam, Reyes Dominguez, Susana, Rodgers, Chiara, Rodriguez Campoy, Patricia, Ronan, Laurie, Rosemary, Deheza, Rowan, Courtney, Sadasivam, Kalaimaran, Sanchez Diaz, Juan Ignacio, Sanders, Ron, Santanelli, James, Sapru, Anil, Schneider, James, Sforza, Jesica, Shea, Sara, Shein, Steven L., Sherring, Claire, Sheward, Victoria, Shime, Nobuaki, Shukla, Avani, Siaba Serrate, Alejandro, Sierra, Yamila, Sikora, Lindsay, Silvestre, Catarina, Singleton, Marcy, Sloniewsky, Daniel, Smith, Rebecca, Smith, Lincoln, Song, Hanqiu, Sousa Moniz, Marta, Spaeder, Michael, Spear, Debbie, Spinella, Philip, Starck, Julie, Stoneman, Erin, Su, Felice, Subramanian, Gayathri, Sullivan, Erin, Sundararajan, Santosh, Sweberg, Todd, Sykes, Kim, Tabata, Yuichi, Tai, Chian Wern, Tala, Joana, Tang, Swee Fong, Tantalean, José, Taylor, Ryan, Thomas, Neal, Tibby, Shane, Tieves, Kelly S, Torero, Luis, Torres, Silvio Fabia, Totapally, Balagangadhar, Travert, Brendan, Truemper, Edward, Turón, Gonzalo, Typpo, Katri, Valle, Juan Ramón, Vargas G, Sonia I, Vasquez Hoyos, Pablo, Vasquez Miranda, Daniel, Vavrina, Martin, Vidal, Nilda Águeda, Virk, Manpreet, Walsh, Laura, Wegner Araya, Adriana, Weitz, James, Wellisch, Lawren, Wellman, Paul, Willson, Douglas, Woods, Katherine, Yehya, Nadir, Yerovi, Rocio, Yunger, Toni, Zuluaga Orrego, Cesar, Zurek, Jiri, Khemani, Robinder G, Lopez-Fernandez, Yolanda M, Klein, Margaret J, Kneyber, Martin C J, Fernandez, Analia, Newth, Christopher J L, and Thomas, Neal J

Published
2019
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12. Impact of Continuous Renal Replacement Therapy Initiation Time, Kidney Injury, and Hypervolemia in Critically Ill Children.

Author

Hadley, Sierra, Thompson, Julie, Beltramo, Fernando, Marcum, John, and Reuter-Rice, Karin

Subjects
HYPERVOLEMIA, HEALTH services accessibility, PEARSON correlation (Statistics), CRITICALLY ill, PATIENTS, CREATININE, KRUSKAL-Wallis Test, HEMODIALYSIS, ACUTE kidney failure, RETROSPECTIVE studies, MANN Whitney U Test, DESCRIPTIVE statistics, BLOOD urea nitrogen, PEDIATRICS, INTENSIVE care units, URBAN hospitals, ELECTRONIC health records, TREATMENT delay (Medicine), LENGTH of stay in hospitals, QUALITY assurance, DATA analysis software, TIME, CHILDREN
Abstract

Background: The mortality rate of pediatric patients who require continuous renal replacement therapy is approximately 42%, and outcomes vary considerably depending on underlying disease, illness severity, and time of dialysis initiation. Delay in the initiation of such therapy may increase mortality risk, prolong intensive care unit stay, and worsen clinical outcomes. Local Problem: In the pediatric intensive care unit of an urban level I trauma children's hospital, continuous renal replacement therapy initiation times and factors associated with delays in therapy were unknown. Methods: This quality improvement process involved a retrospective review of data on patients who received continuous dialysis in the pediatric intensive care unit from January 1, 2017, to December 31, 2021. The objectives were to examine the characteristics of the children requiring continuous renal replacement therapy, therapy initiation times, and factors associated with initiation delays that might affect unit length of stay and mortality. Results: During the study period, 175 patients received continuous renal replacement therapy, with an average initiation time of 11.9 hours. Statistically significant associations were found between the degree of fluid overload and mortality (P <.001) and between the presence of acute kidney injury and prolonged length of stay (P =.04). No significant association was found between therapy initiation time and unit length of stay or mortality, although the average initiation time of survivors was 5.9 hours shorter than that of nonsurvivors. Conclusion: Future studies are needed to assess real time delays and to evaluate if the implementation of a standardized initiation process decreases initiation time. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Physical Rehabilitation in Critically Ill Children: A Multicenter Point Prevalence Study in the United States

Author

Kudchadkar, Sapna R., Nelliot, Archana, Awojoodu, Ronke, Vaidya, Dhananjay, Traube, Chani, Walker, Tracie, Needham, Dale M., Agus, Michael S. D., Coughlin-Wells, Kerry, Babbitt, Christopher J., Basnet, Sangita, Spenner, Allison, Bailey, Christine, Lee, Kristen N., Behrens, Deanna, Donovan, Ramona, Betters, Kristina A., Canter, Marguerite O., Bone, Meredith F., VandenBranden, Sara, Bysani, Gokul Kris, Chrisman, Maddie, Fink, Ericka L., Christie, LeeAnn, Christopher, Jean, Cifra, Christina, Lilitwat, Weerapong, Cooper, David S., Rice, Alicia, Cowl, Allison S., Custer, Jason W., Chung, Melissa G., Van Damme, Danielle, Smith, Kristen A., Dixon, Rebecca, Dorfman, Molly V., Mancini, Ashley, Dial, Sharon P., Di Gennaro, Jane L., Dervan, Leslie A., Doughty, Lesley, Benken, Laura, Dugan, Mark C., Ari, Judith Ben, Flaigle, Melanie Cooper, Smith, Vianne, Gertz, Shira J., Gregersen, Katherine, Abd-Allah, Shamel A., Hamrick, Justin, Irby, Katherine, Herbsman, Jodi, Al-Qaqaa, Yasir M., Holcroft, John, Hulfish, Erin, Culver, Kathleen, Hupp, Susan, DeMonbrun, Andrea, Iheagwara, Kelechi, Lavigne-Sims, Shelli, Joyce, Christine, Traube, Chani, Kamat, Pradip, Stone, Cheryl, Kamath, Sameer S., Harward, Melissa, Kaszubski, Priscilla, Daguanno, Joanne, Kavanagh, Robert P., Spear, Debbie, Kawai, Yu, Fryer, Karen, Kramer, Bree, Kreml, Erin M., Burrows, Brian T., Kiragu, Andrew W., Lane, John, Le, Truc M., Williams, Stacey R., Lin, John C., Florin, Amanda, Luckett, Peter M., Robertson, Tammy, Madrigal, Vanessa N., Harlow, Ashleigh B., Markovitz, Barry, Beltramo, Fernando, McCrory, Michael C., McKinney, Robin L., Naim, Maryam Y., Nair, Asha G., Thiagarajan, Ravi, Narayan, Shilpa, Murkowski, Kathleen, Gowda, Keshava Murthy Narayana, See, Jhoclay, Nawathe, Pooja A., Novotny, William E., Keel, Cynthia, Oishi, Peter, Marupudi, Neelima, Ortmann, Laura, O’Meara, A. M. Iqbal, Miller Ferguson, Nikki, Peters, Megan E., Pinto, Neethi, Kniola, Allison, Rowan, Courtney M., Mazurczyk, Jill, Shah, Shilpa, Lachman, Sage, Singleton, Marcy N., Nett, Sholeen T., Spaeder, Michael C., Zschaebitz, Jenna V., Spentzas, Thomas, Sreedhar, Sue S., Steffen, Katherine M., Chen, Michelle, Stormorken, Anne, Blatz, Allison, Tadphale, Sachin D., Tasker, Robert C., Griffin, John F., Uhl, Tammy L., Harward, Melissa, Walson, Karen H., Bates, Cynthia, Watson, Christopher M., Sheram, Mary Lynn, Williams, Cydni N., Kirby, Aileen, Wolf, Michael, Lowry, Kellet, Wolfe, Heather A., Yates, Andrew R., and Beckman, Brian

Published
2020
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17. Critical Care and Mechanical Ventilation Practices Surrounding Liver Transplantation in Children: A Multicenter Collaborative*

Author

Maue, Danielle K., primary, Martinez, Mercedes, additional, Alcamo, Alicia, additional, Beltramo, Fernando, additional, Betters, Kristina, additional, Nares, Michael, additional, Jeyapalan, Asumthia, additional, Zinter, Matthew, additional, Kamath, Sameer, additional, Ridall, Leslie, additional, Monde, Alexandra, additional, Resch, Joseph, additional, Kaushik, Shubhi, additional, Kang, Elise, additional, Mangus, Richard S., additional, Pike, Francis, additional, and Rowan, Courtney M., additional

Published
2022
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18. A multicenter study of ICU resource utilization in pediatric, adolescent and young adult patients post CAR-T therapy

Author

Ragoonanan, Dristhi, primary, Bhar, Saleh, additional, Mohan, Gopi, additional, Beltramo, Fernando, additional, Khazal, Sajad J., additional, Hurley, Caitlin, additional, Andersen, Clark, additional, Margossian, Steven, additional, Neelapu, Sattva S., additional, Shpall, Elizabeth, additional, Gutierrez, Cristina, additional, Tewari, Priti, additional, Shoberu, Basirat, additional, Talleur, Aimee, additional, McCall, David, additional, Nunez, Cesar, additional, Cuglievan, Branko, additional, Tambaro, Francesco Paolo, additional, Petropoulos, Demetrios, additional, Abdel-Azim, Hisham, additional, and Mahadeo, Kris M., additional

Published
2022
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21. 1165: PREDICTIVE FACTORS FOR POSTOPERATIVE MECHANICAL VENTILATION IN PEDIATRIC LIVER TRANSPLANT PATIENTS

Author

Maue, Danielle, primary, Martinez, Mercedes, additional, Beltramo, Fernando, additional, Alcamo, Alicia, additional, Ridall, Leslie, additional, Nares, Michael, additional, Jeyapalan, Asumthia, additional, Zinter, Matthew, additional, Betters, Kristina, additional, Kamath, Sameer, additional, Monde, Alexandra, additional, Kaushik, Shubhi, additional, Resch, Joseph, additional, Kang, Elise, additional, Pike, Francis, additional, Mangus, Richard, additional, and Rowan, Courtney, additional

Published
2021
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24. 589: Predictive Factors for Bleeding Complications in Children Post Liver Transplant

Author

Maue, Danielle, primary, Alcamo, Alicia, additional, Beltramo, Fernando, additional, Betters, Kristina, additional, Kamath, Sameer, additional, Kaushik, Shubhi, additional, Mangus, Richard, additional, Martinez, Mercedes, additional, Monde, Alexandra, additional, Nares, Michael, additional, Resch, Joseph, additional, Ridall, Leslie, additional, Zinter, Matthew, additional, and Rowan, Courtney, additional

Published
2020
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25. Reply to Letter to the Editor

Author

Beltramo, Fernando, Menteer, Jandavid, Razavi, Asma, Khemani, Robinder G., Szmuszkovicz, Jacqueline, Newth, Christopher J. L., and Ross, Patrick A.

Published
2016
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29. 369

Author

Young, Sarah, primary, Ross, Patrick, additional, and Beltramo, Fernando, additional

Published
2019
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32. 966

Author

Devarashetty, Sushil, primary, Beltramo, Fernando, additional, and Totapally, Balagangadhar, additional

Published
2015
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33. 297

Author

Beltramo, Fernando, primary, Raszynski, Andre, additional, and Totapally, Balagangadhar, additional

Published
2015
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34. 1291

Author

Figueroa, Dominick, primary, Rivera, Jose Hernandez, additional, and Beltramo, Fernando, additional

Published
2015
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35. 1110

Author

Totapally, Abhinav, primary, Leoncio, Michael, additional, Beltramo, Fernando, additional, Meyer, Keith, additional, Raszynski, Andre, additional, and Totapally, Balagangadhar, additional

Published
2015
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37. 223

Author

Peters, Eric, primary, Beltramo, Fernando, additional, DeMarco, Alicia, additional, and Del Castillo, Sylvia, additional

Published
2014
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38. 1062

Author

Peters, Eric, primary, Razavi, Asma, additional, Beltramo, Fernando, additional, Wong, Ronald, additional, Wong, Wendy, additional, Moromisato, David, additional, and Amirnovin, Rambod, additional

Published
2013
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39. 330

Author

Razavi, Asma, primary, Beltramo, Fernando, additional, Newth, Christopher, additional, Khemani, Robinder, additional, and Ross, Patrick, additional

Published
2013
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