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1. Endovascular therapy in patients with a large ischemic volume at presentation: An aggregate patient-level analysis

Author

Kerleroux, Basile, Hak, Jean François, Lapergue, Bertrand, Bricout, Nicolas, Zhu, François, Inoue, Manabu, Janot, Kevin, Dargazanli, Cyril, Kaesmacher, Johannes, Rouchaud, Aymeric, Forestier, Géraud, Gortais, Hugo, Benzakoun, Joseph, Yoshimoto, Takeshi, Consoli, Arturo, Ben Hassen, Wagih, Henon, Hilde, Naggara, Olivier, and Boulouis, Grégoire

Published
2024
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3. Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial

Author

Alonso, Angelika, Arquizan, Caroline, Barreau, Xavier, Beaujeux, Rémy, Behme, Daniel, Boeckh-Behrens, Tobias, Boehme, Christian, Boix, Martí, Boulouis, Grégoire, Bricout, Nicolas, Broc, Nicolas, Cereda, Carlo W., Chabert, Emmanuel, Cho, Tae-Hee, Cianfoni, Alessandro, Costalat, Vincent, Denier, Christian, Di Maria, Frederico, du Mesnil de Rochemont, Richard, Fearon, Patricia, Ferrier, Anna, Fischer, Sebastian, Gauberti, Maxime, Gaudron, Marie, Gimenez, Laetitia, Globas, Christoph, Görtler, Michael, Goyal, Mayank, Hilker-Roggendorf, Ruediger, Hill, Michael D., Hua, Vi Tuan, Humbertjean, Lisa, Jansen, Olav, Jung, Simon, Kägi, Georg, Kelly, Michael E., Kleffner, Ilka, Knoflach, Michael, Nedeltchev, Krassen, Krause, Lars Udo, Lappalainen, Kimmo, Lefebvre, Margaux, Leyon, Joe, Liao, Liang, Liegey, Jean-Sebastien, Loehr, Christian, Michel, Patrik, Nannoni, Stefania, Nicholson, Patrick, Nico, Lorena, Obadia, Michael, Ognard, Julien, Ogungbemi, Ayokunle, Olivot, Jean-Marc, Escalard, Simon, Pasi, Marco, Peeling, Lissa, Perez, Jane, Petersen, Martina, Piechowiak, Eike, Raposo, Roberto, Räty, Silja, Reitz, Sarah C., Remollo, Sebastià, Remonda, Luca, Rennie, Ian, Requena, Manuel, Riabikin, Alexander, Riva, Roberto, Rouchaud, Aymeric, Rosi, Andrea, Rubiera, Marta, Spelle, Laurent, Schnieder, Marlena, Schaafsma, Joanna D., Schubert, Tilman, Schulz, Jörg B., Siddiqui, Mohammed, Soize, Sébastien, Sonnberger, Michael, Touze, Emmanuel, Triquenot, Aude, Turc, Guillaume, Vieira, Lucy, Ben Hassen, Wagih, Wagner, Judith N., Wasser, Katrin, Weber, Johannes, Wenz, Holger, Weisenburger-Lile, David, Wodarg, Fritz, Wolff, Valérie, Wunderlich, Silke, Fischer, Urs, Kaesmacher, Johannes, Strbian, Daniel, Eker, Omer, Cognard, Christoph, Plattner, Patricia S, Bütikofer, Lukas, Mordasini, Pasquale, Deppeler, Sandro, Pereira, Vitor M, Albucher, Jean François, Darcourt, Jean, Bourcier, Romain, Benoit, Guillon, Papagiannaki, Chrysanthi, Ozkul-Wermester, Ozlem, Sibolt, Gerli, Tiainen, Marjaana, Gory, Benjamin, Richard, Sébastien, Liman, Jan, Ernst, Marielle Sophie, Boulanger, Marion, Barbier, Charlotte, Mechtouff, Laura, Zhang, Liqun, Marnat, Gaultier, Sibon, Igor, Nikoubashman, Omid, Reich, Arno, Consoli, Arturo, Lapergue, Bertrand, Ribo, Marc, Tomasello, Alejandro, Saleme, Suzana, Macian, Francisco, Moulin, Solène, Pagano, Paolo, Saliou, Guillaume, Carrera, Emmanuel, Janot, Kevin, Hernández-Pérez, María, Pop, Raoul, Schiava, Lucie Della, Luft, Andreas R, Piotin, Michel, Gentric, Jean Christophe, Pikula, Aleksandra, Pfeilschifter, Waltraud, Arnold, Marcel, Siddiqui, Adnan H, Froehler, Michael T, Furlan, Anthony J, Chapot, René, Wiesmann, Martin, Machi, Paolo, Diener, Hans-Christoph, Kulcsar, Zsolt, Bonati, Leo H, Bassetti, Claudio L, Mazighi, Mikael, Liebeskind, David S, Saver, Jeffrey L, and Gralla, Jan

Published
2022
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4. Endovascular Therapy or Medical Management Alone for Isolated Posterior Cerebral Artery Occlusion: A Multicenter Study

Author

Sabben, Candice, Charbonneau, Frédérique, Delvoye, François, Strambo, Davide, Heldner, Mirjam R., Ong, Elodie, Ter Schiphorst, Adrien, Henon, Hilde, Ben Hassen, Wagih, Agasse-Lafont, Thomas, Legris, Loïc, Sibon, Igor, Wolff, Valérie, Sablot, Denis, Elhorany, Mahmoud, Preterre, Cécile, Nehme, Nour, Soize, Sébastien, Weisenburger-Lile, David, Triquenot-Bagan, Aude, Mione, Gioia, Aignatoaie, Andreea, Papassin, Jérémie, Poll, Roxana, Béjot, Yannick, Carrera, Emmanuel, Garnier, Pierre, Michel, Patrik, Saliou, Guillaume, Mordasini, Pasquale, Berthezene, Yves, Costalat, Vincent, Bricout, Nicolas, Albers, Gregory W., Mazighi, Mikael, Turc, Guillaume, Seners, Pierre, Antonenko, Kateryna, Arquizan, Caroline, Benammar, Lynda, Boutet, Claire, Clarençon, Frédéric, Comby, Pierre-Olivier, Desal, Hubert, Detante, Olivier, Eugene, François, Gerardin, Emmanuel, Gory, Benjamin, Kremer, Stéphane, Ledure, Sylvain, Krug, Mathieu, Lapergue, Bertrand, Niclot, Philippe, Magni, Christophe, Obadia, Michael, Ozsancak, Canan, Pico, Fernando, Pilgram-Pastor, Sara, Pop, Raoul, Richard, Sébastien, Rosso, Charlotte, Savatovsky, Julien, Moulin, Solène, Tracol, Clément, and Zbinden, Martin

Published
2023
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7. Early Recanalization Among Patients Undergoing Bridging Therapy With Tenecteplase or Alteplase

Author

Checkouri, Thomas, primary, Gerschenfeld, Gaspard, additional, Seners, Pierre, additional, Yger, Marion, additional, Ben Hassen, Wagih, additional, Chausson, Nicolas, additional, Olindo, Stéphane, additional, Caroff, Jildaz, additional, Marnat, Gaultier, additional, Clarençon, Frédéric, additional, Baron, Jean-Claude, additional, Turc, Guillaume, additional, Alamowitch, Sonia, additional, Arquizan, Caroline, additional, Berthezene, Yves, additional, Boulouis, Grégoire, additional, Bracard, Serge, additional, Bricout, Nicolas, additional, Cho, Tae-Hee, additional, Consoli, Arturo, additional, Costalat, Vincent, additional, Cottier, Jean-Philippe, additional, Debiais, Séverine, additional, Gory, Benjamin, additional, Henon, Hilde, additional, Lapergue, Bertrand, additional, Obadia, Michael, additional, Oppenheim, Catherine, additional, Pico, Fernando, additional, Piotin, Michel, additional, Richard, Sébastien, additional, Zuber, Mathieu, additional, Blanc, Clémence, additional, Calvet, David, additional, Denier, Christian, additional, Ghazanfari, Sam, additional, Kalsoum, Erwah, additional, L’Hermitte, Yann, additional, Legrand, Laurence, additional, Liegey, Jean-Sebastien, additional, Milnerowicz, Malgorzata, additional, Naggara, Olivier, additional, Poli, Mathilde, additional, Premat, Kévin, additional, Sibon, Igor, additional, Sabben, Candice, additional, Shotar, Eimad, additional, Smadja, Didier, additional, and Spelle, Laurent, additional

Published
2023
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8. Acute Stroke Management During the COVID-19 Pandemic: Does Confinement Impact Eligibility for Endovascular Therapy?

Author

Hajdu, Steven D., Pittet, Valerie, Puccinelli, Francesco, Ben Hassen, Wagih, Ben Maacha, Malek, Blanc, Raphaël, Bracco, Sandra, Broocks, Gabriel, Bartolini, Bruno, Casseri, Tommaso, Clarençon, Frederic, Naggara, Olivier, Eugène, François, Ferré, Jean-Christophe, Guédon, Alexis, Houdart, Emmanuel, Krings, Timo, Lehmann, Pierre, Limbucci, Nicola, Machi, Paolo, Macho, Juan, Mandruzzato, Nicolo, Nappini, Sergio, Nawka, Marie Teresa, Nicholson, Patrick, Marto, João Pedro, Pereira, Vitor, Correia, Manuel A., Pinho-e-Melo, Teresa, Nuno Ramos, João, Raz, Eytan, Ferreira, Patrícia, Reis, João, Shapiro, Maksim, Shotar, Eimad, van Horn, Noel, Piotin, Michel, and Saliou, Guillaume

Published
2020
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9. Mechanical Thrombectomy for Acute Ischemic Stroke Amid the COVID-19 Outbreak: Decreased Activity, and Increased Care Delays

Author

Kerleroux, Basile, Fabacher, Thibaut, Bricout, Nicolas, Moïse, Martin, Testud, Benoit, Vingadassalom, Sivadji, Ifergan, Héloïse, Janot, Kévin, Consoli, Arturo, Ben Hassen, Wagih, Shotar, Eimad, Ognard, Julien, Charbonnier, Guillaume, L’Allinec, Vincent, Guédon, Alexis, Bolognini, Federico, Marnat, Gaultier, Forestier, Géraud, Rouchaud, Aymeric, Pop, Raoul, Raynaud, Nicolas, Zhu, François, Cortese, Jonathan, Chalumeau, Vanessa, Berge, Jérome, Escalard, Simon, and Boulouis, Grégoire

Published
2020
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12. Better Collaterals Are Independently Associated With Post-Thrombolysis Recanalization Before Thrombectomy

Author

Seners, Pierre, Roca, Pauline, Legrand, Laurence, Turc, Guillaume, Cottier, Jean-Philippe, Cho, Tae-Hee, Arquizan, Caroline, Bracard, Serge, Ozsancak, Canan, Ben Hassen, Wagih, Naggara, Olivier, Lion, Stéphanie, Debiais, Séverine, Berthezene, Yves, Costalat, Vincent, Richard, Sébastien, Magni, Christophe, Mas, Jean-Louis, Baron, Jean-Claude, and Oppenheim, Catherine

Published
2019
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14. Rescue intracranial permanent stenting for refractory occlusion following thrombectomy: a propensity matched analysis

Author

Ifergan, Heloise, primary, Dargazanli, Cyril, additional, Ben Hassen, Wagih, additional, Hak, Jean-Francois, additional, Gory, Benjamin, additional, Ognard, Julien, additional, Premat, Kevin, additional, Marnat, Gaultier, additional, Kerleroux, Basile, additional, Zhu, François, additional, Bellanger, Guillaume, additional, Sporns, Peter B, additional, Charbonnier, Guillaume, additional, Forestier, Géraud, additional, Caroff, Jildaz, additional, Fauché, Cédric, additional, Clarençon, Frédéric, additional, Janot, Kevin, additional, Lapergue, Bertrand, additional, and Boulouis, Gregoire, additional

Published
2023
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16. Efficacy of Endovascular Therapy in Acute Ischemic Stroke Depends on Age and Clinical Severity

Author

Le Bouc, Raphaël, Clarençon, Frédéric, Meseguer, Elena, Lapergue, Bertrand, Consoli, Arturo, Turc, Guillaume, Naggara, Olivier, Duong, Duc Long, Servan, Jerome, Reiner, Peggy, Labeyrie, Marc Antoine, Fisselier, Mathieu, Blanc, Raphaël, Farhat, Wassim, Pires, Christine, Zuber, Mathieu, Obadia, Michael, Mazighi, Mikael, Pico, Fernando, Mas, Jean-Louis, Amarenco, Pierre, Samson, Yves, Rosso, Charlotte, Crozier, Sophie, Deltour, Sandrine, Leger, Anne, Baronnet, Flore, Frasca-Polara, Giulia, Diaz, Belen, Sourour, Nader, Di Maria, Frederico, Pistocchi, Silvia, Bartolini, Bruno, Hobeanu, Christina, Rigual, Ricardo, Guidoux, Céline, Cabrejo, Lucie, Lavallée, Philippa, Martin-Bechet, Anna, Sabben, Candice, Bourdain, Frédéric, Wang, Adrien, Evrard, Serge, Decroix, Jean-Pierre, Tchikviladze, Maya, Tisserand, Marie, Rodesch, Georges, Coskun, Oguzhan, Seners, Pierre, Isabel, Clothilde, Lamy, Catherine, Domigo, Valérie, Birchenall, Julia, Guiraud, Vincent, Bodiguel, Eric, Calvet, David, Trystram, Denis, Rodriguez-Régent, Christine, Ben Hassen, Wagih, Boulouis, Grégoire, Godon-Hardy, Sylvie, Méder, Jean-François, Oppenheim, Catherine, Zeghoudi, Anne-Cécile, Nifle, Chantal, Yeung, Jennifer, Stanciu, Daniela, Buch, Dan, Chadenat, Marie-Laure, Girbovan, Aandrei, Bayon, Laeticia, Troussiere, Anne-Cécile, Calinescu, Georgina, Rostomashvili, Sophio, SudaveschiVeronica, de Malherbe, Maxime, Chabriat, Hugues, Jouvent, Eric, Herve, Dominique, Porcher, Frédérique, Bouquet-Castiglione, Floriane, Morvan, Typhaine, Lyoubi-Idrissi, Aïcha, Cognat, Emmanuel, Join Lambert, Claire, Tamazyan, Ruben, and Gerber, Sophie

Published
2018
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17. Rescue intracranial permanent stenting for refractory occlusion following thrombectomy: a propensity matched analysis

Author

Ifergan, Heloise, Dargazanli, Cyril, Ben Hassen, Wagih, Hak, Jean-Francois, Gory, Benjamin, Ognard, Julien, Premat, Kevin, Marnat, Gaultier, Kerleroux, Basile, Zhu, Francois, Bellanger, Guillaume, Sporns, Peter B, Charbonnier, Guillaume, Forestier, Géraud, Caroff, Jildaz, Fauché, Cédric, Clarencon, Frédéric, Janot, Kevin, Lapergue, Bertrand, and Boulouis, Gregoire

Abstract

BackgroundRescue intracranial stenting (RIS) can be used in refractory large vessel occlusion (LVO) after mechanical thrombectomy (MT). We aimed to assess the safety and efficacy of RIS versus a propensity matched sample of patients with persistent LVO.MethodsWe retrospectively analysed a multicenter retrospective pooled cohort of patients with anterior LVO (2015−2021) treated with MT, and identified patients with at least three passes and a modified Thrombolysis In Cerebral Infarction (mTICI) score of 0 to 2a. Propensity score matching was used to account for determinants of outcome in patients with or without RIS. The study outcomes included 3 months modified Rankin Scale (mRS) and symptomatic hemorrhagic transformation (HT).Results420 patients with a refractory anterior occlusion were included, of which 101 were treated with RIS (mean age 69 years). Favorable outcome (mRS 0–2) was more frequent in patients with a patent stent at day 1 (53% vs 6%, P<0.001), which was independently associated with an early dual antiplatelet regimen (P<0.05). In the propensity matched sample, patients treated with RIS versus without RIS had similar rates of favorable outcomes (36.8% vs 30.3%, P=0.606). Patients with RIS showed a favorable shift in the overall mRS distributions (common adjusted OR 0.74, 95% CI 0.60 to 0.91, P=0.006). Symptomatic HT was marginally more frequent in the RIS group (9% vs 3%, P=0.07), and there was no difference in 3-month mortality.ConclusionIn selected patients with a refractory intracranial occlusion despite at least three thrombectomy passes, RIS may be associated with an overall shift towards more favorable clinical outcome, and no significant increase in the odds of symptomatic HT or death.

Published
2024
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18. Diagnostic performance of dynamic 3D magnetic resonance angiography in daily practice for the detection of intracranial arteriovenous shunts in patients with non-traumatic intracranial hemorrhage

Author

Roumi, Arnaud, primary, Ben Hassen, Wagih, additional, Hmeydia, Ghazi, additional, Posener, Sacha, additional, Pallud, Johan, additional, Sharshar, Tarek, additional, Calvet, David, additional, Mas, Jean-Louis, additional, Baron, Jean-Claude, additional, Oppenheim, Catherine, additional, Naggara, Olivier, additional, and Turc, Guillaume, additional

Published
2023
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19. Internal carotid artery patency after mechanical thrombectomy for stroke due to occlusive dissection: Impact on outcome

Author

Scopelliti, Giuseppe, primary, Karam, Arnaud, additional, Labreuche, Julien, additional, Bricout, Nicolas, additional, Marrama, Federico, additional, Diomedi, Marina, additional, Ben Hassen, Wagih, additional, Leclerc, Xavier, additional, Cordonnier, Charlotte, additional, Henon, Hilde, additional, and Casolla, Barbara, additional

Published
2022
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20. Should Patients With Acute Minor Ischemic Stroke With Isolated Internal Carotid Artery Occlusion Be Thrombolysed?

Author

Boulenoir, Naouel, primary, Turc, Guillaume, additional, Ter Schiphorst, Adrien, additional, Heldner, Mirjam R., additional, Strambo, Davide, additional, Laksiri, Nadia, additional, Girard Buttaz, Isabelle, additional, Papassin, Jérémie, additional, Sibon, Igor, additional, Chausson, Nicolas, additional, Michel, Patrik, additional, Rosso, Charlotte, additional, Bourdain, Frédéric, additional, Lamy, Chantal, additional, Weisenburger-Lile, David, additional, Agius, Pierre, additional, Yger, Marion, additional, Obadia, Michael, additional, Sablot, Denis, additional, Legris, Nicolas, additional, Jung, Simon, additional, Pilgram-Pastor, Sara, additional, Henon, Hilde, additional, Bernardaud, Lucy, additional, Arquizan, Caroline, additional, Baron, Jean-Claude, additional, Seners, Pierre, additional, Ben Hassen, Wagih, additional, Lapergue, Bertrand, additional, Lucas, Ludovic, additional, Leys, Didier, additional, Philippeau, Frédéric, additional, Bennani, Omar, additional, Mechtouff, Laura, additional, Klapczynski, Frédéric, additional, Detante, Olivier, additional, Costalat, Vincent, additional, Mione, Gioia, additional, Gazzola, Sébastien, additional, Debiais, Séverine, additional, Cakmak, Serkan, additional, Grigoras, Valer, additional, Denier, Christian, additional, Smadja, Didier, additional, Mounier-Vehier, François, additional, Peres, Roxane, additional, Spelle, Laurent, additional, Bricout, Nicolas, additional, Bracard, Serge, additional, Triquenot, Aude, additional, Lyoubi, Aïcha, additional, Cottier, Jean-Philippe, additional, Duong, Duc-Long, additional, and Ollivier, Camille, additional

Published
2022
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21. Perfusion Imaging and Clinical Outcome in Acute Minor Stroke With Large Vessel Occlusion

Author

Seners, Pierre, primary, Arquizan, Caroline, additional, Fontaine, Louis, additional, Ben Hassen, Wagih, additional, Heldner, Mirjam R., additional, Strambo, Davide, additional, Nagel, Simon, additional, Carrera, Emmanuel, additional, Mechtouff, Laura, additional, McCullough-Hicks, Margy, additional, Mohammaden, Mahmoud H., additional, Cottier, Jean-Philippe, additional, Henon, Hilde, additional, Aignatoaie, Andreea, additional, Laksiri, Nadia, additional, Papassin, Jérémie, additional, Lucas, Ludovic, additional, Garnier, Pierre, additional, Triquenot, Aude, additional, Mione, Gioia, additional, Hajdu, Steven, additional, Costalat, Vincent, additional, Potreck, Arne, additional, Detante, Olivier, additional, Bonneville, Fabrice, additional, Berthezene, Yves, additional, Bracard, Serge, additional, Sibon, Igor, additional, Bricout, Nicolas, additional, Boutet, Claire, additional, Mordasini, Pasquale, additional, Michel, Patrik, additional, Oppenheim, Catherine, additional, Olivot, Jean-Marc, additional, Nogueira, Raul G., additional, Albers, Gregory W., additional, Baron, Jean-Claude, additional, Turc, Guillaume, additional, Cognard, Christophe, additional, Marnat, Gaultier, additional, Menegon, Patrice, additional, Ledure, Sylvain, additional, Dargazanli, Cyril, additional, Cho, Tae-Hee, additional, Nighoghossian, Norbert, additional, Eker, Omer, additional, Gouttard, Sylvain, additional, Haussen, Diogo, additional, Debiais, Séverine, additional, Charron, Vladimir, additional, Charron, Nicolas, additional, Leys, Didier, additional, Ozsancak, Canan, additional, Delpech, Mathilde, additional, Brunel, Hervé, additional, Papagiannaki, Chrysanti, additional, Girardin, Emmanuel, additional, Richard, Sébastien, additional, Gory, Benjamin, additional, Zbinden, Martin, additional, Dobrocky, Tomas, additional, Ringelb, Peter, additional, and Möhlenbruch, Markus, additional

Published
2022
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25. Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial

Author

Fischer, Urs, primary, Kaesmacher, Johannes, additional, Strbian, Daniel, additional, Eker, Omer, additional, Cognard, Christoph, additional, Plattner, Patricia S, additional, Bütikofer, Lukas, additional, Mordasini, Pasquale, additional, Deppeler, Sandro, additional, Pereira, Vitor M, additional, Albucher, Jean François, additional, Darcourt, Jean, additional, Bourcier, Romain, additional, Benoit, Guillon, additional, Papagiannaki, Chrysanthi, additional, Ozkul-Wermester, Ozlem, additional, Sibolt, Gerli, additional, Tiainen, Marjaana, additional, Gory, Benjamin, additional, Richard, Sébastien, additional, Liman, Jan, additional, Ernst, Marielle Sophie, additional, Boulanger, Marion, additional, Barbier, Charlotte, additional, Mechtouff, Laura, additional, Zhang, Liqun, additional, Marnat, Gaultier, additional, Sibon, Igor, additional, Nikoubashman, Omid, additional, Reich, Arno, additional, Consoli, Arturo, additional, Lapergue, Bertrand, additional, Ribo, Marc, additional, Tomasello, Alejandro, additional, Saleme, Suzana, additional, Macian, Francisco, additional, Moulin, Solène, additional, Pagano, Paolo, additional, Saliou, Guillaume, additional, Carrera, Emmanuel, additional, Janot, Kevin, additional, Hernández-Pérez, María, additional, Pop, Raoul, additional, Schiava, Lucie Della, additional, Luft, Andreas R, additional, Piotin, Michel, additional, Gentric, Jean Christophe, additional, Pikula, Aleksandra, additional, Pfeilschifter, Waltraud, additional, Arnold, Marcel, additional, Siddiqui, Adnan H, additional, Froehler, Michael T, additional, Furlan, Anthony J, additional, Chapot, René, additional, Wiesmann, Martin, additional, Machi, Paolo, additional, Diener, Hans-Christoph, additional, Kulcsar, Zsolt, additional, Bonati, Leo H, additional, Bassetti, Claudio L, additional, Mazighi, Mikael, additional, Liebeskind, David S, additional, Saver, Jeffrey L, additional, Gralla, Jan, additional, Alonso, Angelika, additional, Arquizan, Caroline, additional, Barreau, Xavier, additional, Beaujeux, Rémy, additional, Behme, Daniel, additional, Boeckh-Behrens, Tobias, additional, Boehme, Christian, additional, Boix, Martí, additional, Boulouis, Grégoire, additional, Bricout, Nicolas, additional, Broc, Nicolas, additional, Cereda, Carlo W., additional, Chabert, Emmanuel, additional, Cho, Tae-Hee, additional, Cianfoni, Alessandro, additional, Costalat, Vincent, additional, Denier, Christian, additional, Di Maria, Frederico, additional, du Mesnil de Rochemont, Richard, additional, Fearon, Patricia, additional, Ferrier, Anna, additional, Fischer, Sebastian, additional, Gauberti, Maxime, additional, Gaudron, Marie, additional, Gimenez, Laetitia, additional, Globas, Christoph, additional, Görtler, Michael, additional, Goyal, Mayank, additional, Hilker-Roggendorf, Ruediger, additional, Hill, Michael D., additional, Hua, Vi Tuan, additional, Humbertjean, Lisa, additional, Jansen, Olav, additional, Jung, Simon, additional, Kägi, Georg, additional, Kelly, Michael E., additional, Kleffner, Ilka, additional, Knoflach, Michael, additional, Nedeltchev, Krassen, additional, Krause, Lars Udo, additional, Lappalainen, Kimmo, additional, Lefebvre, Margaux, additional, Leyon, Joe, additional, Liao, Liang, additional, Liegey, Jean-Sebastien, additional, Loehr, Christian, additional, Michel, Patrik, additional, Nannoni, Stefania, additional, Nicholson, Patrick, additional, Nico, Lorena, additional, Obadia, Michael, additional, Ognard, Julien, additional, Ogungbemi, Ayokunle, additional, Olivot, Jean-Marc, additional, Escalard, Simon, additional, Pasi, Marco, additional, Peeling, Lissa, additional, Perez, Jane, additional, Petersen, Martina, additional, Piechowiak, Eike, additional, Raposo, Roberto, additional, Räty, Silja, additional, Reitz, Sarah C., additional, Remollo, Sebastià, additional, Remonda, Luca, additional, Rennie, Ian, additional, Requena, Manuel, additional, Riabikin, Alexander, additional, Riva, Roberto, additional, Rouchaud, Aymeric, additional, Rosi, Andrea, additional, Rubiera, Marta, additional, Spelle, Laurent, additional, Schnieder, Marlena, additional, Schaafsma, Joanna D., additional, Schubert, Tilman, additional, Schulz, Jörg B., additional, Siddiqui, Mohammed, additional, Soize, Sébastien, additional, Sonnberger, Michael, additional, Touze, Emmanuel, additional, Triquenot, Aude, additional, Turc, Guillaume, additional, Vieira, Lucy, additional, Ben Hassen, Wagih, additional, Wagner, Judith N., additional, Wasser, Katrin, additional, Weber, Johannes, additional, Wenz, Holger, additional, Weisenburger-Lile, David, additional, Wodarg, Fritz, additional, Wolff, Valérie, additional, and Wunderlich, Silke, additional

Published
2022
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28. Effect of intravenous thrombolysis before endovascular therapy on outcome according to collateral status: insight from the ETIS Registry

Author

Anadani, Mohammad, primary, Januel, Anne-Christine, additional, Finitsis, Stephanos, additional, Clarençon, Frédéric, additional, Richard, Sébastien, additional, Marnat, Gaultier, additional, Bourcier, Romain, additional, Sibon, Igor, additional, Dargazanli, Cyril, additional, Arquizan, Caroline, additional, Blanc, Raphael, additional, Lapergue, Bertrand, additional, Consoli, Arturo, additional, Eugene, Francois, additional, Vannier, Stephane, additional, Caroff, Jildaz, additional, Denier, Christian, additional, Boulanger, Marion, additional, Gauberti, Maxime, additional, Rouchaud, Aymeric, additional, Macian Montoro, Francisco, additional, Rosso, Charlotte, additional, Ben Hassen, Wagih, additional, Turc, Guillaume, additional, Ozkul-Wermester, Ozlem, additional, Papagiannaki, Chrysanthi, additional, Albucher, Jean François, additional, Le Bras, Anthony, additional, Evain, Sarah, additional, Wolff, Valerie, additional, Pop, Raoul, additional, Timsit, Serge, additional, Gentric, Jean-Christophe, additional, Bourdain, Frederic, additional, Veunac, Louis, additional, de Havenon, Adam, additional, Liebeskind, David S, additional, Maier, Benjamin, additional, and Gory, Benjamin, additional

Published
2022
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29. Carotid artery direct access for mechanical thrombectomy: the Carotid Artery Puncture Evaluation (CARE) study

Author

Dumas, Victor, primary, Kaesmacher, Johannes, additional, Ognard, Julien, additional, Forestier, Géraud, additional, Dargazanli, Cyril, additional, Janot, Kevin, additional, Behme, Daniel, additional, Shotar, Eimad, additional, Chabert, Emmanuel, additional, Velasco, Stéphane, additional, Bricout, Nicolas, additional, Ben Hassen, Wagih, additional, Veunac, Louis, additional, Geismar, Maxime, additional, Eugene, Francois, additional, Detraz, Lili, additional, Darcourt, Jean, additional, L'Allinec, Vincent, additional, Eker, Omer F, additional, Consoli, Arturo, additional, Maus, Volker, additional, Gariel, Florent, additional, Marnat, Gaultier, additional, Papanagiotou, Panagiotis, additional, Papagiannaki, Chrisanthi, additional, Escalard, Simon, additional, Meyer, Lukas, additional, Lobsien, Donald, additional, Abdullayev, Nuran, additional, Chalumeau, Vanessa, additional, Neau, Jean Philippe, additional, Guillevin, Rémy, additional, Boulouis, Gregoire, additional, Rouchaud, Aymeric, additional, Styczen, Hanna, additional, and Fauché, Cédric, additional

Published
2021
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31. Relevance of Brain Regions' Eloquence Assessment in Patients With a Large Ischemic Core Treated With Mechanical Thrombectomy

Author

Kerleroux, Basile, primary, Benzakoun, Joseph, additional, Janot, Kévin, additional, Dargazanli, Cyril, additional, Eraya, Dimitri Daly, additional, Ben Hassen, Wagih, additional, Zhu, François, additional, Gory, Benjamin, additional, Hak, Jean-Francois, additional, Perot, Charline, additional, Detraz, Lili, additional, Bourcier, Romain, additional, Aymeric, Rouchaud, additional, Forestier, Géraud, additional, Marnat, Gaultier, additional, Gariel, Florent, additional, Mordasini, Pasquale, additional, Seners, Pierre, additional, Turc, Guillaume, additional, Kaesmacher, Johannes, additional, Oppenheim, Catherine, additional, Naggara, Olivier, additional, and Boulouis, Gregoire, additional

Published
2021
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32. Effect of Operator’s Experience on Proficiency in Mechanical Thrombectomy: A Multicenter Study

Author

Zhu, François, primary, Ben Hassen, Wagih, additional, Bricout, Nicolas, additional, Kerleroux, Basile, additional, Janot, Kevin, additional, Gory, Benjamin, additional, Anxionnat, René, additional, Richard, Sébastien, additional, Marchal, Adrien, additional, Blanc, Raphael, additional, Piotin, Michel, additional, Consoli, Arturo, additional, Trystram, Denis, additional, Rodriguez Regent, Christine, additional, Desilles, Jean-Philippe, additional, Weisenburger-Lile, David, additional, Escalard, Simon, additional, Herbreteau, Denis, additional, Ifergan, Heloise, additional, Lima Maldonado, Igor, additional, Labreuche, Julien, additional, Henon, Hilde, additional, Naggara, Olivier, additional, Lapergue, Bertrand, additional, Boulouis, Grégoire, additional, Hocine, Redjem, additional, Gabriele, Ciccio, additional, Stanislas, Smajda, additional, Benjamin, Maier, additional, Mikael, Mazighi, additional, Mikael, Obadia, additional, Candice, Sabben, additional, Roxanne, Peres, additional, Ovide, Corabianu, additional, Thomas, De Broucker, additional, Didier, Smadja, additional, Sonia, Alamowitch, additional, Olivier, Ille, additional, Eric, Manchon, additional, Pierre-Yves, Garcia, additional, Guillaume, Taylor, additional, Malek, Ben Maacha, additional, Adrien, Wang, additional, Serge, Evrard, additional, Maya, Tchikviladze, additional, Nadia, Ajili, additional, Lucas, Gorza, additional, Géraldine, Buard, additional, Oguzhan, Coskun, additional, Maria Federico, Di, additional, Georges, Rodesh, additional, Sergio, Zimatore, additional, Morgan, Leguen, additional, Julie, Gratieux, additional, Fernando, Pico, additional, Haja, Rakotoharinandrasana, additional, Philippe, Tassan, additional, Roxanna, Poll, additional, Sylvie, Marinier, additional, Norbert, Nighoghossian, additional, Roberto, Riva, additional, Omer, Eker, additional, Francis, Turjman, additional, Laurent, Derex, additional, Tae-Hee, Cho, additional, Laura, Mechtouff, additional, Lukaszewicz Anne, Claire, additional, Frédéric, Philippeau, additional, Serkan, Cakmak, additional, Karine, Blanc-Lasserre, additional, Anne-Evelyne, Vallet, additional, Gaultier, Marnat, additional, Florent, Gariel, additional, Xavier, Barreau, additional, Jérôme, Berge, additional, Patrice, Menegon, additional, Igor, Sibon, additional, Sebastien, Liegey, additional, Stéphane, Olindo, additional, Pauline, Renou, additional, Sharmila, Sagnier, additional, Mathilde, Poli, additional, Sabrina, Debruxelles, additional, Nicolas, Pangon, additional, Romain, Bourcier, additional, Lili, Detraz, additional, Benjamin, Daumas-Duport, additional, Pierre-Louis, Alexandre, additional, Monica, Roy, additional, Cédric, Lenoble, additional, Vincent, L’allinec, additional, Jean-Baptiste, Girot, additional, Hubert, Desal, additional, Serge, Bracard, additional, Marc, Braun, additional, Anne-Laure, Derelle, additional, Romain, Tonnelet, additional, Liang, Liao, additional, Patricio, Muszynski, additional, Emmanuelle, Schmitt, additional, Sophie, Planel, additional, Lisa, Humbertjean, additional, Gioia, Mione, additional, Jean-Christophe, Lacour, additional, Nolwenn, Riou-Comte, additional, Gérard, Audibert, additional, Marcela, Voicu, additional, Ionel, Alb, additional, Marie, Reitter, additional, Madalina, Brezeanu, additional, Agnès, Masson, additional, Ioana, Tabarna Adriana, Podar, additional, Francisco, Macian-Montoro, additional, Suzanna, Saleme, additional, Charbel, Mounayer, additional, Aymeric, Rouchaud, additional, Vincent, Costalat, additional, Caroline, Arquizan, additional, Cyril, Dargazanli, additional, Grégory, Gascou, additional, Pierre-Henri, Lefèvre, additional, Imad, Derraz, additional, Carlos, Riquelme, additional, Nicolas, Gaillard, additional, Isabelle, Mourand, additional, Lucas, Corti, additional, Eugene, Francois, additional, Stéphane, Vannier, additional, Jean-Christophe, Ferre, additional, Helene, Raoult, additional, Thomas, Ronziere, additional, Maria, Lassale, additional, Christophe, Paya, additional, Jean-Yves, Gauvrit, additional, Clément, Tracol, additional, Sophie, Langnier-Lemercier, additional, Yves, Samson, additional, Charlotte, Rosso, additional, Anne, Leger, additional, Sandrine, Deltour, additional, Frederic, Clarencon, additional, Eimad, Shotar, additional, Laurent, Spelle, additional, Christian, Denier, additional, Olivier, Chassin, additional, Vanessa, Chalumeau, additional, Jildaz, Caroff, additional, Laura, Venditti, additional, Guillaume, Turc, additional, Pierre, Seners, additional, Valérie, Domigo, additional, Catherine, Lamy, additional, Julia, Birchenall, additional, Clothilde, Isabel, additional, Alain, Viguier, additional, Christophe, Cognard, additional, Anne, Christine Januel, additional, Jean-Marc, Olivot, additional, Nicolas, Raposo, additional, Fabrice, Bonneville, additional, Albucher Jean, François, additional, Lionel, Calviere, additional, Emmanuel, Touze, additional, Charlotte, Barbier, additional, Romain, Schneckenburger, additional, Marion, Boulanger, additional, Julien, Cogez, additional, Sophie, Guettier, additional, Serge, Timsit, additional, Jean-Christophe, Gentric, additional, Julien, Ognard, additional, Francois, Mathias Merrien, additional, Ozlem, Ozkul Wermester, additional, Evelyne, Massardier, additional, Chrysanthi, Papagiannaki, additional, Frédéric, Bourdain, additional, Bernady, Patricia, additional, Laurent, Lagoarde-Segot, additional, Hélène, Cailliez, additional, Louis, Veunac, additional, David, Higue, additional, Valérie, Wolff, additional, Raoul, Pop, additional, Rémi, Beaujeux, additional, Dan-Sorin, Mihoc, additional, Monica, Manisor, additional, Anthony, Le Bras, additional, Sarah, Evain, additional, Arnaud, Le Guen, additional, Sebastian, Richter, additional, Regis, Hubrecht, additional, Stéphanie, Demasles, additional, Bruno, Barroso, additional, Mathieu, Zuber, additional, Wassim, Farhat, additional, Quentin, Alias, additional, François, Lun, additional, Delphine, Stenvenoot, additional, Olivier, Heinzlef, additional, Sylvie, Godon Hardy, additional, Valentin, Bohotin, additional, and Jérôme, Grimaud, additional

Published
2021
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33. Impact of Repeated Clot Retrieval Attempts on Infarct Growth and Outcome After Ischemic Stroke

Author

Ben Hassen, Wagih, primary, Touloupas, Caroline, additional, Benzakoun, Joseph, additional, Boulouis, Gregoire, additional, Bretzner, Martin, additional, Bricout, Nicolas, additional, Legrand, Laurence, additional, Rodriguez, Christine, additional, Le Berre, Alice, additional, Seners, Pierre, additional, Turc, Guillaume, additional, Cordonnier, Charlotte, additional, Oppenheim, Catherine, additional, Henon, Hilde, additional, and Naggara, Olivier, additional

Published
2021
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35. Predictors of poor outcome despite successful endovascular treatment for ischemic stroke: results from the MR CLEAN Registry

Author

van de Graaf, Rob A, primary, Samuels, Noor, additional, Chalos, Vicky, additional, Lycklama a Nijeholt, Geert J, additional, van Beusekom, Heleen, additional, Yoo, Albert J, additional, van Zwam, Wim H, additional, Majoie, Charles B L M, additional, Roos, Yvo B W E M, additional, van Doormaal, Pieter Jan, additional, Ben Hassen, Wagih, additional, van der Lugt, Aad, additional, Dippel, Diederik W J, additional, Lingsma, Hester F, additional, van Es, Adriaan C G M, additional, and Roozenbeek, Bob, additional

Published
2021
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37. Prognosis and risk factors associated with asymptomatic intracranial hemorrhage after endovascular treatment of large vessel occlusion stroke: a prospective multicenter cohort study

Author

Constant Dit Beaufils, Pacôme, Labreuche, Julien, Richard, Śebastien, Fahed, Robert, Desal, Hubert Armand, Piotin, Michel P., Blanc, Raphaël, Redjem, Hocine, Escalard, Simon, Desilles, Jean Philippe, Ciccio, Gabriele, Smajda, Stanislas, Maier, Benjamin, Mazighi, Mikael, Obadia, Mikael, Sabben, Candice, Peres, Roxanne, Corabianu, Ovide, De Broucker, Thomas, Smadja, Didier, Alamowitch, Sonia, Ille, Olivier, Manchon, Eric, Garcia, Pierre Yves, Taylor, Guillaume, Ben Maacha, Malek, Wang, Adrien, Evrard, Serge, Tchikviladze, Maya, Ajili, Nadia, Lapergue, Bertrand, Weisenburger, David, Gorza, Lucas, Buard, Géraldine, Coskun, Oguzhan, Consoli, Arturo, Di Maria, Federico, Rodesh, Georges, Zimatore, Sergio, Leguen, Morgan, Gratieux, Julie D., Pico, Fernando, Rakotoharinandrasana, Haja, Tassan, Philippe, Poll, Roxanna, Marinier, Sylvie, Nighoghossian, Norbert, Riva, Roberto, Eker, Omer faruk, Turjman, Francis, Derex, Laurent, Cho, Tae-Hee, Mechtouff, Laura, Lukaszewicz, Anne Claire, Philippeau, Frédéric, Cakmak, Serkan, Blanc-Lasserre, Karine, Vallet, Anne Evelyne, Marnat, Gaultier, Gariel, Florent, Barreau, Xavier, Berge, Jerome, Veunac, Louis, Menegon, Patrice, Sibon, Igor, Lucas, Ludovic, Olindo, Stéphane, Renou, Pauline, Sagnier, Sharmila, Poli, Mathilde, Debruxelles, Sabrina, Tourdias, Thomas, Liegey, Jean Sebastien, Bourcier, Romain, Detraz, Lili, Daumas-Duport, Benjamin, Alexandre, Pierre Louis, Roy, Monica, Lenoble, Cédric, L’Allinec, Vincent, Girot, Jean Baptiste, Desal, Hubert, Guillon, Benoît, De Gaalon, Solène, Preterre, Cécile, Gory, Benjamin, Bracard, Serge R., Anxionnat, René, Braun, Marc, Derelle, Anne Laure, Tonnelet, Romain, Liao, Liang, Zhu, François, Schmitt, Emmanuelle, Planel, Sophie, Richard, Sébastien, Humbertjean, Lisa, Mione, Gioia, Lacour, Jean Christophe, Bonnerot, Mathieu, Riou-Comte, Nolwenn, Macian-Montoro, Francisco, Saleme, Suzanna, Mounayer, Charbel, Rouchaud, Aymeric M., Costalat, Vincent, Arquizan, Caroline, Dargazanli, Cyril, Gascou, Grégory, Lefèvre, Pierre Henri, Derraz, Imad, Riquelme, Carlos, Gaillard, Nicolas, Mourand, Isabelle, Corti, Lucas, Francois, Eugene, Vannier, Stéphane, Ferré, Jean-Christophe, Raoult, Hélène, Ronziere, Thomas, Lassale, Maria, Paya, Christophe, Gauvrit, Jean Yves, Tracol, Clément, Langnier-Lemercier, Sophie, Samson, Yves, Rosso, Charlotte, Leger, Anne, Deltour, Sandrine, Clarencon, Frédéric, Shotar, Eimad, Spelle, Laurent, Denier, Christian, Chalumeau, Vanessa, Caroff, Jildaz, Chassin, Olivier, Venditti, Laura, Turc, G., Naggara, Olivier N., Boulouis, Grégoire, Ben Hassen, Wagih, Seners, Pierre, Viguier, Alain, Cognard, Christophe H., Januel, Anne Christine, Olivot, Jean Marc, Raposo, Nicolas, Bonneville, Fabrice, Touze, Emmanuel, Barbier, Charlotte N., Schneckenburger, Romain, Boulanger, Marion, Cogez, Julien, Guettier, Sophie, Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Service Neuroradiologie diagnostique et interventionnelle [Hôpital Foch], Hôpital Foch [Suresnes], Imagerie Adaptative Diagnostique et Interventionnelle (IADI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Département de neuroradiologie diagnostique et thérapeutique [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), P.C.D.B. and J.L. have nothing to disclose. R. Blanc, R. Bourcier, A.C., H.D., F.D.M., R.F., F.G., B. Gory, G.M., C.P., S.R., I.S. and F.Z. have nothing to disclose. M.M. reports personal fees from Amgen, personal fees from Boerhinger, personal fees from Acticor, and personal fees from Air Liquide, outside the submitted work. B.L. reports grants from Stryker, Penumbra and Microventino, outside the submitted work. S.D.G. reports personal fees and non‐financial support from Boerhinger, outside the submitted work. B. Guillon reports personal fees from Boerhinger‐Ingelheim France and Bristol‐Myers‐Squibb, outside the submitted work., Centre hospitalier universitaire de Nantes (CHU Nantes), Evaluation des technologies de santé et des pratiques médicales - ULR 2694 (METRICS), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Service de neuroradiologie [Suresnes], Service de neurologie [Bordeaux], CHU Bordeaux [Bordeaux]-Groupe hospitalier Pellegrin, Département de Neuro-Radiologie [Bordeaux] (DNR - Bordeaux), CHU Bordeaux [Bordeaux], Service de neurologie [CHRU Nancy], Défaillance Cardiovasculaire Aiguë et Chronique (DCAC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Unité de recherche de l'institut du thorax (ITX-lab), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), and The Ottawa Hospital

Subjects
Male, endovascular treatment, medicine.medical_specialty, Asymptomatic, Brain Ischemia, Cohort Studies, Coronary artery disease, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Modified Rankin Scale, Internal medicine, Humans, Medicine, asymptomatic, Registries, 030212 general & internal medicine, Stroke, Thrombectomy, Intracerebral hemorrhage, business.industry, Endovascular Procedures, Odds ratio, medicine.disease, intracerebral hemorrhage, stroke, Confidence interval, 3. Good health, Treatment Outcome, Neurology, Cardiology, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Neurology (clinical), prognosis, medicine.symptom, business, Intracranial Hemorrhages, 030217 neurology & neurosurgery, Cohort study
Abstract

International audience; Background and purpose: Asymptomatic intracranial hemorrhage (aICH) is a common occurrence after endovascular treatment (EVT) for acute ischemic stroke (AIS). The aims of this study were to address its impact on 3-month functional outcome and to identify risk factors for aICH after EVT. Methods: Patients with AIS attributable to anterior circulation large vessel occlusion who underwent EVT were enrolled in a multicenter prospective registry. Based on imaging performed 22–36 h post-EVT, we included patients with no intracranial hemorrhage (ICH) or aICH. Poor outcome defined as a 3-month modified Rankin Scale (mRS) score 4–6 and overall 3-month mRS score distribution were compared according to presence/absence of aICH, and aICH subtype using logistic regression. We assessed the risk factors of aICH using a multivariate logistic regression model. Results: Of the 1526 patients included in the study, 653 (42.7%) had aICH. Patients with aICH had a higher rate of poor outcome: odds ratio (OR) 1.88 (95% confidence interval [CI] 1.44–2.44). Shift analysis of mRS score found a fully adjusted OR of 1.79 (95% CI 1.47–2.18). Hemorrhagic infarction (OR 1.63 [95% CI 1.22–2.18]) and parenchymal hematoma (OR 2.99 [95% CI 1.77–5.02]) were associated with higher risk of poor outcome. Male sex, diabetes, coronary artery disease, baseline National Institutes of Health Stroke Scale score and Alberta Stroke Program Early Computed Tomography Score, number of passes and onset to groin puncture time were independently associated with aICH. Conclusions: Patients with aICH, irrespective of the radiological pattern, have a worse functional outcome at 3 months compared with those without ICH after EVT for AIS. The number of EVT passes and the time from onset to groin puncture are factors that could be modified to reduce deleterious ICH.

Published
2021

38. Effect of intravenous thrombolysis before endovascular therapy on outcome according to collateral status: insight from the ETIS Registry

Author

Anadani, Mohammad, Januel, Anne-Christine, Finitsis, Stephanos, Clarencon, Frédéric, Richard, Sébastien, Marnat, Gaultier, Bourcier, Romain, Sibon, Igor, Dargazanli, Cyril, Arquizan, Caroline, Blanc, Raphael, Lapergue, Bertrand, Consoli, Arturo, Eugene, Francois, Vannier, Stephane, Caroff, Jildaz, Denier, Christian, Boulanger, Marion, Gauberti, Maxime, Rouchaud, Aymeric, Macian Montoro, Francisco, Rosso, Charlotte, Ben Hassen, Wagih, Turc, Guillaume, Ozkul-Wermester, Ozlem, Papagiannaki, Chrysanthi, Albucher, Jean Francois, Le Bras, Anthony, Evain, Sarah, Wolff, Valerie, Pop, Raoul, Timsit, Serge, Gentric, Jean-Christophe, Bourdain, Frederic, Veunac, Louis, de Havenon, Adam, Liebeskind, David S, Maier, Benjamin, and Gory, Benjamin

Abstract

BackgroundIt is unknown whether collateral status modifies the effect of pretreatment intravenous thrombolysis (IVT) on the outcomes of patients with large vessel occlusions treated with endovascular therapy (EVT). We aimed to assess whether collateral status modifies the effect of IVT on the outcomes of EVT in clinical practice.MethodsWe used data from the ongoing prospective multicentric Endovascular Treatment in Ischemic Stroke (ETIS) Registry in France. Patients with anterior circulation proximal large vessel occlusions treated with EVT within 6 hours of symptom onset were enrolled. Patients were divided into two groups based on pretreatment with IVT. The two groups were matched based on baseline characteristics. We tested the interaction between collateral status and IVT in unadjusted and adjusted models.ResultsA total of 1589 patients were enrolled in the study, of whom 55% received IVT. Using a propensity score matching method, 724 no IVT patients were matched to 549 IVT patients. In propensity score weighted analysis, IVT was associated with higher odds of early neurological improvement (OR 1.74; 95% CI 1.33 to 2.26), favorable functional outcome (OR 1.66; 95% CI 1.23 to 2.24), excellent functional outcome (OR 2.04; 95% CI 1.47 to 2.83), and successful reperfusion (OR 2.18; 95% CI 1.51 to 3.16). IVT was not associated with mortality or hemorrhagic complications. There was no interaction between collateral status and IVT association with any of the outcomes.ConclusionsCollateral status does not modify the effect of pretreatment IVT on the efficacy and safety outcomes of EVT.

Published
2023
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39. Mechanical thrombectomy practices in France: Exhaustive survey of centers and individual operators

Author

Forestier, Géraud, primary, Kerleroux, Basile, additional, Janot, Kévin, additional, Zhu, François, additional, Dumas, Victor, additional, Hak, Jean-François, additional, Shotar, Eimad, additional, Ben Hassen, Wagih, additional, Bourcier, Romain, additional, Soize, Sébastien, additional, Berge, Jérome, additional, Naggara, Olivier, additional, Desal, Hubert, additional, Boulouis, Grégoire, additional, Rouchaud, Aymeric, additional, Hanafi, R., additional, L’Allinec, V., additional, Girot, J.-B., additional, Charbonnier, G., additional, Biondi, A., additional, Gariel, F., additional, Marnat, G., additional, Ognard, J., additional, Gentric, J.-C., additional, Barbier, C., additional, Chabert, E., additional, Lebedinsky, P., additional, Tuilier, T., additional, Thouant, P., additional, Comby, P.-O., additional, Mejdoubi, M., additional, Heck, O., additional, Kastler, A., additional, Chalumeau, V., additional, Caroff, J., additional, Personnic, T., additional, Marchal, A., additional, Bogey, C., additional, Eker, O., additional, Carle, X., additional, Dargazanli, C., additional, Derraz, I., additional, Gory, B., additional, Detraz, L., additional, Sedat, J., additional, Zurlinden, O., additional, Escalard, S., additional, Fahed, R., additional, Guedon, A., additional, Civelli, V., additional, Premat, K., additional, Clarençon, F., additional, Ducouret, E., additional, Raynaud, N., additional, Velasco, S., additional, Manceau, P.-F., additional, Paya, C., additional, Eugene, F., additional, Le Moa, J., additional, Papagiannaki, C., additional, Aggour, M., additional, Bintner, M., additional, Veyrieres, J.-B., additional, Richter, J.S., additional, Pop, R., additional, Consoli, A., additional, Di-Maria, F., additional, Arteaga, C., additional, Darcourt, J., additional, Michelozzi, C., additional, Guedin, P., additional, Herbreteau, D., additional, and Le Bras, A., additional

Published
2020
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40. Mechanical Thrombectomy for Acute Ischemic Stroke Amid the COVID-19 Outbreak in France: Decreased Activity, and Increased Care Delays

Author

Kerleroux, Basile, primary, Fabacher, Thibaut, additional, Bricout, Nicolas, additional, Moise, Martin, additional, Testud, Benoit, additional, Vingadassalom, Sivadji, additional, Ifergan, Héloise, additional, Janot, Kévin, additional, Consolli, Arturo, additional, Ben Hassen, Wagih, additional, Shotar, Eimad, additional, Ognard, Julien, additional, Charbonnier, Guillaume, additional, L’allinec, Vincent, additional, Guedon, Alexis, additional, Bolognini, Federico, additional, Marnat, Gaultier, additional, Forestier, Géraud, additional, Rouchaud, Aymeric, additional, Pop, Raoul, additional, Raynaud, Nicolas, additional, Zhu, François, additional, Cortese, Jonathan, additional, Chalumeau, Vanessa, additional, Escalard, Simon, additional, Berge, Jérome, additional, and Boulouis, Grégoire, additional

Published
2020
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41. Functional Outcome, Recanalization, and Hemorrhage Rates After Large Vessel Occlusion Stroke Treated With Tenecteplase Before Thrombectomy.

Author

Gerschenfeld, Gaspard, Smadja, Didier, Turc, Guillaume, Olindo, Stephane, Laborne, François-Xavier, Yger, Marion, Caroff, Jildaz, Gonçalves, Bruno, Seners, Pierre, Cantier, Marie, l'Hermitte, Yann, Aghasaryan, Manvel, Alecu, Cosmin, Marnat, Gaultier, Ben Hassen, Wagih, Kalsoum, Erwah, Clarençon, Frédéric, Piotin, Michel, Spelle, Laurent, and Denier, Christian

Published
2021
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42. Post-Thrombolysis Recanalization in Stroke Referrals for Thrombectomy

Author

Seners, Pierre, Turc, Guillaume, Naggara, Olivier, Hénon, Hilde, Piotin, Michel, Arquizan, Caroline, Cho, Tae-Hee, Narata, Ana-Paula, Lapergue, Bertrand, Richard, Sébastien, Legrand, Laurence, Bricout, Nicolas, Blanc, Raphaël, Dargazanli, Cyril, Gory, Benjamin, Debiais, Séverine, Tisserand, Marie, Bracard, Serge, Leclerc, Xavier, Obadia, Michael, Costalat, Vincent, Berner, Lise-Prune, Cottier, Jean-Philippe, Consoli, Arturo, Ducrocq, Xavier, Mas, Jean-Louis, Oppenheim, Catherine, Baron, Jean-Claude, Abrivard, Marie, Alamowitch, Sonia, Ben Hassen, Wagih, Berthezène, Yves, Blanc-Lasserre, Karine, Boulin, Anne, Boulouis, Grégoire, Bouly, Stephane, Bourdain, Frédéric, Calvet, David, Charron, Vladimir, Chbicheb, Mohamed, Condette-Auliac, Stéphanie, Corabianu, Ovide, Cordonnier, Charlotte, Coskun, Oguzhan, De Broucker, Thomas, Decroix, Jean-Pierre, Di Maria, Federico, Evrard, Serge, Fissellier, Mathieu, Girard, Isabelle, Lalu, Thibault, Le Coz, Patrick, Le Guen, Morgan, Ille, Olivier, Leys, Didier, Magni, Christophe, Manchon, Eric, Mazighi, Mikael, Mounier-Vehier, François, Moynier, Marinette, Muresan, Ioan-Paul, Nighoghossian, Norbert, Ong, Elodie, Ozsancak, Canan, Philippeau, Frédéric, Pico, Fernando, Rodesch, Georges, Rosolacci, Thierry, Sabben, Candice, Sablot, Denis, Tassan, Philippe, Tchikviladze, Maya, Turjman, Francis, Vallet, Anne-Evelyne, Wang, Adrien, Zins, Marc, Zuber, Mathieu, Centre Hospitalier Sainte Anne [Paris], Institut de psychiatrie et neurosciences (U894 / UMS 1266), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de neurologie[Lille], Université de Lille, Droit et Santé-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Fondation Ophtalmologique Adolphe de Rothschild [Paris], Département de neurologie [Montpellier], Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Gui de Chauliac [Montpellier]-Université de Montpellier (UM), Cerebrovascular Unit [Lyon], Hôpital neurologique et neurochirurgical Pierre Wertheimer [CHU - HCL], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Service de neuroradiologie [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS), Hôpital Foch [Suresnes], Service de neurologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Services de neuroradiologie [Lille], Hôpital Roger Salengro-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Département de Neuroradiologie[Montpellier], Département de neuroradiologie diagnostique et thérapeutique [CHRU Nancy], Université de Montpellier (UM), Hospices Civils de Lyon (HCL), Centre hospitalier régional Metz-Thionville (CHR Metz-Thionville), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Département de neurologie [Lille], Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Gui de Chauliac [CHU Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Université de Montpellier (UM), Hôpital Roger Salengro [Lille]-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Imagerie Adaptative Diagnostique et Interventionnelle (IADI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), and Hôpital Gui de Chauliac [Montpellier]-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Université Montpellier 1 (UM1)-Université de Montpellier (UM)

Subjects
[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, thrombectomy, incidence, magnetic resonance imaging, fibrinolysis, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], stroke
Abstract

International audience; Background and Purpose—Whether all acute stroke patients with large vessel occlusion need to undergo intravenous thrombolysis before mechanical thrombectomy (MT) is debated as (1) the incidence of post-thrombolysis early recanalization (ER) is still unclear; (2) thrombolysis may be harmful in patients unlikely to recanalize; and, conversely, (3) transfer for MT may be unnecessary in patients highly likely to recanalize. Here, we determined the incidence and predictors of post-thrombolysis ER in patients referred for MT and derive ER prediction scores for trial design. Methods—Registries from 4 MT-capable centers gathering patients referred for MT and thrombolyzed either on site (mothership) or in a non MT-capable center (drip-and-ship) after magnetic resonance– or computed tomography–based imaging between 2015 and 2017. ER was identified on either first angiographic run or noninvasive imaging. In the magnetic resonance imaging subsample, thrombus length was determined on T2*-based susceptibility vessel sign. Independent predictors of no- ER were identified using multivariable logistic regression models, and scores were developed according to the magnitude of regression coefficients. Similar registries from 4 additional MT-capable centers were used as validation cohort. Results—In the derivation cohort (N=633), ER incidence was ≈20%. In patients with susceptibility vessel sign (n=498), no-ER was independently predicted by long thrombus, proximal occlusion, and mothership paradigm. A 6-point score derived from these variables showed strong discriminative power for no-ER (C statistic, 0.854) and was replicated in the validation cohort (n=353; C statistic, 0.888). A second score derived from the whole sample (including negative T2* or computed tomography–based imaging) also showed good discriminative power and was similarly validated. Highest grades on both scores predicted no-ER with >90% specificity, whereas low grades did not reliably predict ER. Conclusions—The substantial ER rate underlines the benefits derived from thrombolysis in bridging populations. Both prediction scores afforded high specificity for no-ER, but not for ER, which has implications for trial design.

Published
2018

43. Correlation of age at time of aneurysmal subarachnoid hemorrhage within families

Author

Dalemans, Diana J.Z., Mensing, Liselore A., Bourcier, Romain, Aggour, Mohamed, Ben Hassen, Wagih, Lindgren, Antti E., Koivisto, Timo, Jääskeläinen, Juha E., Rinkel, Gabriel J.E., Ruigrok, Ynte M., Dalemans, Diana J.Z., Mensing, Liselore A., Bourcier, Romain, Aggour, Mohamed, Ben Hassen, Wagih, Lindgren, Antti E., Koivisto, Timo, Jääskeläinen, Juha E., Rinkel, Gabriel J.E., and Ruigrok, Ynte M.

Published
2019

44. Correlation of age at time of aneurysmal subarachnoid hemorrhage within families

Author

UMC Utrecht, Opleiding Neurologie, Brain, ZL Cerebrovasculaire Ziekten Medisch, Neurologie, Circulatory Health, Dalemans, Diana J.Z., Mensing, Liselore A., Bourcier, Romain, Aggour, Mohamed, Ben Hassen, Wagih, Lindgren, Antti E., Koivisto, Timo, Jääskeläinen, Juha E., Rinkel, Gabriel J.E., Ruigrok, Ynte M., UMC Utrecht, Opleiding Neurologie, Brain, ZL Cerebrovasculaire Ziekten Medisch, Neurologie, Circulatory Health, Dalemans, Diana J.Z., Mensing, Liselore A., Bourcier, Romain, Aggour, Mohamed, Ben Hassen, Wagih, Lindgren, Antti E., Koivisto, Timo, Jääskeläinen, Juha E., Rinkel, Gabriel J.E., and Ruigrok, Ynte M.

Published
2019

45. Association of Time From Stroke Onset to Groin Puncture With Quality of Reperfusion After Mechanical Thrombectomy A Meta-analysis of Individual Patient Data From 7 Randomized Clinical Trials

Author

Bourcier, Romain, Goyal, Mayank, Liebeskind, David S., Muir, Keith W., Desal, Hubert, Siddiqui, Adnan H., Dippel, Diederik W. J., Majoie, Charles B., van Zwam, Wim H., Jovin, Tudor G., Levy, Elad I., Mitchell, Peter J., Berkhemer, Olvert A., Davis, Stephen M., Derraz, Linad, Donnan, Geoffrey A., Demchuk, Andrew M., van Oostenbrugge, Robert J., Kelly, Michael, Roos, Yvo B., Jahan, Reza, van der Lugt, Aad, Sprengers, Marieke, Velasco, Stephane, Nijeholt, Geert J. Lycklama A., Ben Hassen, Wagih, Burns, Paul, Brown, Scott, Chabert, Emmanuel, Krings, Timo, Chloe, Hana, Weimar, Christian, Campbell, Bruce C. V., Ford, Gary A., Ribo, Marc, White, Phil, Cloud, Geoffrey C., San Roman, Luis, Davalos, Antoni, Naggara, Olivier, Hill, Michael D., Bracard, Serge, HERMES Trialists Collaboration, Bourcier, Romain, Goyal, Mayank, Liebeskind, David S., Muir, Keith W., Desal, Hubert, Siddiqui, Adnan H., Dippel, Diederik W. J., Majoie, Charles B., van Zwam, Wim H., Jovin, Tudor G., Levy, Elad I., Mitchell, Peter J., Berkhemer, Olvert A., Davis, Stephen M., Derraz, Linad, Donnan, Geoffrey A., Demchuk, Andrew M., van Oostenbrugge, Robert J., Kelly, Michael, Roos, Yvo B., Jahan, Reza, van der Lugt, Aad, Sprengers, Marieke, Velasco, Stephane, Nijeholt, Geert J. Lycklama A., Ben Hassen, Wagih, Burns, Paul, Brown, Scott, Chabert, Emmanuel, Krings, Timo, Chloe, Hana, Weimar, Christian, Campbell, Bruce C. V., Ford, Gary A., Ribo, Marc, White, Phil, Cloud, Geoffrey C., San Roman, Luis, Davalos, Antoni, Naggara, Olivier, Hill, Michael D., Bracard, Serge, and HERMES Trialists Collaboration

Abstract

IMPORTANCE Reperfusion is a key factor for clinical outcome in patients with acute ischemic stroke (AIS) treated with endovascular thrombectomy (EVT) for large-vessel intracranial occlusion. However, data are scarce on the association between the time from onset and reperfusion results.OBJECTIVE To analyze the rate of reperfusion after EVT started at different intervals after symptom onset in patients with AIS.DESIGN, SETTING, AND PARTICIPANTS We conducted a meta-analysis of individual patient data from 7 randomized trials of the Highly Effective Reperfusion Using Multiple Endovascular Devices (HERMES) group. This is a multicenter cohort study of the intervention arm of randomized clinical trials included in the HERMES group. Patients with anterior circulation AIS who underwent EVT for M1/M2 or intracranial carotid artery occlusion were included. Each trial enrolled patients according to its specific inclusion and exclusion criteria. Data on patients eligible but not enrolled (eg, refusals or exclusions) were not available. All analyses were performed by the HERMES biostatistical core laboratory using the pooled database. Data were analyzed between December 2010 and April 2015.MAIN OUTCOMES AND MEASURES Successful reperfusion was defined as a modified thrombolysis in cerebral infarction score of 2b/3 at the end of the EVT procedure adjusted for age, occlusion location, pretreatment intravenous thrombolysis, and clot burden score and was analyzed in relation to different intervals (onset, emergency department arrival, imaging, and puncture) using mixed-methods logistic regression.RESULTS Among the 728 included patients, with a mean (SD) age of 65.4 (13.5) years and of whom 345 were female (47.4%), decreases in rates of successful reperfusion defined as a thrombolysis in cerebral infarction score of 2b/3 were observed with increasing time from admission or first imaging to groin puncture. The magnitude of effect was a 22% relative reduct

Published
2019

46. Small vessel disease in patients with subarachnoid hemorrhage: Prevalence and associations with vasospasm occurrence, severity and clinical outcomes

Author

Villain, Adrien, primary, Boulouis, Grégoire, additional, Ben Hassen, Wagih, additional, Rodriguez-Regent, Christine, additional, Trystram, Denis, additional, Edjlali, Myriam, additional, Nataf, François, additional, Sauvageon, Xavier, additional, Sharshar, Tarek, additional, Meder, Jean F, additional, Oppenheim, Catherine, additional, and Naggara, Olivier, additional

Published
2019
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47. MT-DRAGON score for outcome prediction in acute ischemic stroke treated by mechanical thrombectomy within 8 hours

Author

Ben Hassen, Wagih, primary, Raynaud, Nicolas, additional, Bricout, Nicolas, additional, Boulouis, Gregoire, additional, Legrand, Laurence, additional, Ferrigno, Marc, additional, Kazemi, Apolline, additional, Bretzner, Martin, additional, Soize, Sebastien, additional, Farhat, Wassim, additional, Seners, Pierre, additional, Turc, Guillaume, additional, Zuber, Mathieu, additional, Oppenheim, Catherine, additional, Cordonnier, Charlotte, additional, Naggara, Olivier, additional, and Henon, Hilde, additional

Published
2019
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49. Imaging Findings After Mechanical Thrombectomy in Acute Ischemic Stroke

Author

Puntonet, Julien, primary, Richard, Marie-Edith, additional, Edjlali, Myriam, additional, Ben Hassen, Wagih, additional, Legrand, Laurence, additional, Benzakoun, Joseph, additional, Rodriguez-Régent, Christine, additional, Trystram, Denis, additional, Naggara, Olivier, additional, Méder, Jean-Francois, additional, Boulouis, Grégoire, additional, and Oppenheim, Catherine, additional

Published
2019
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50. Thrombectomie mécanique chez les patients présentant un gros volume d’infarctus: intérêt de l’imagerie de perfusion. Étude multicentrique coopérative du JENI

Author

Kerleroux, Basile, primary, Janot, Kevin, additional, Dargazanli, Cyril, additional, Daly Eraya, Dimitri, additional, Ben Hassen, Wagih, additional, Gory, Benjamin, additional, Zhu, François, additional, Hak, Jean François, additional, Perot, Charline, additional, Gariel, Florent, additional, Marnat, Gaultier, additional, Rouchaud, Aymeric, additional, Forestier, Géraud, additional, Detraz, Lili, additional, Bourcier, Romain, additional, and Boulouis, Grégoire, additional

Published
2019
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