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The solid tumors of the child are characterized, apart from their evolution, by a notable metastatic power, notably in the bone marrow. This study examined a series of 19 cases of children's solid tumors with bone marrow involvement. In the light of this study, we analyzed the different aspects of bone marrow invasion during the initial diagnosis of solid tumors, diagnosed in the pediatric oncology department of the teaching hospital Hassan II -Fez for a five-year period from June 2011 to May 2016. The study of the bone marrow in the malignant solid tumors of the child conditions the therapeutic attitude and the evaluation of the response to the treatment. The presence of medullary metastases darkens the prognosis of these tumors. The role of the laboratory of biology, apart from the standard balances, is essential for the search for extra-hematopoietic cells evoking medullary metastases. [ABSTRACT FROM AUTHOR]