21 results on '"Benešová, Iva"'
Search Results
2. IL-2 and TCR stimulation induce expression and secretion of IL-32β by human T cells.
- Author
-
Sanna, Franziska Christine, Benešová, Iva, Pervan, Philip, Krenz, Adriana, Wurzel, Alexander, Lohmayer, Robert, Mühlbauer, Jasmin, Wöllner, Amélie, Köhl, Nina, Menevse, Ayse Nur, Stamova, Slava, Volpin, Valentina, Beckhove, Philipp, and Xydia, Maria
- Subjects
REGULATORY T cells ,T cell receptors ,T cells ,CANCER cells ,BREAST cancer - Abstract
IL-32 expression is important for pathogen clearance but detrimental in chronic inflammation, autoimmunity, and cancer. T cells are major IL-32 producers in these diseases and key mediators of pathogen and tumor elimination but also autoimmune destruction. However, their contribution to IL-32 biology during immune responses is hardly understood due to several isoforms with divergent inflammatory properties. Here, we identified IL-32β as the predominant isoform in various T cell subsets of healthy individuals and breast cancer patients with the highest levels detected in intratumoral regulatory T cells. We show that IL-32β is induced by IL-2 but IL-32β release requires T Cell Receptor rather than IL2R stimulation. Using inhibitors of protein secretion pathways and serial (ultra)centrifugation of T cell supernatants, we demonstrate that T cells actively secrete IL-32β unconventionally, as a free protein and, to a minor degree, through exosomes. Thus, our data identify activated T cells as major IL-32β secretors in health and cancer. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
3. Type I conventional dendritic cells and CD8+ T cells predict favorable clinical outcome of head and neck squamous cell carcinoma patients.
- Author
-
Kirchner, Johanna, Plesca, Ioana, Rothe, Rebecca, Resag, Antonia, Löck, Steffen, Benešová, Iva, Rupp, Luise, Linge, Annett, Wehner, Rebekka, Krause, Mechthild, and Schmitz, Marc
- Subjects
T cells ,REGULATORY T cells ,SQUAMOUS cell carcinoma ,TREATMENT effectiveness ,DENDRITIC cells ,HEAD & neck cancer - Abstract
Head and neck squamous cell carcinoma (HNSCC) is one of the most common tumor entities worldwide, with human papillomavirus (HPV) infection contributing to cancer development. Conventional therapies achieve only limited efficiency, especially in recurrent or metastatic HNSCC. As the immune landscape decisively impacts the survival of patients and treatment efficacy, this study comprehensively investigated the immunological tumor microenvironment (TME) and its association with patient outcome, with special focus on several dendritic cell (DC) and T lymphocyte subpopulations. Therefore, formalin-fixed paraffin-embedded tumor samples of 56 HNSCC patients, who have undergone resection and adjuvant radiotherapy, were analyzed by multiplex immunohistochemistry focusing on the detailed phenotypic characterization and spatial distribution of DCs, CD8
+ T cells, and T-helper cell subsets in different tumor compartments. Immune cell densities and proportions were correlated with clinical characteristics of the whole HNSCC cohort and different HPV- or hypoxia-associated subcohorts. Tumor stroma was highly infiltrated by plasmacytoid DCs and T lymphocytes. Among the T-helper cells and CD8+ T cells, stromal regulatory T cells and intraepithelial exhausted CD8+ T cells expressing programmed cell death protein-1 (PD-1+ ) and/or lymphocyteactivation gene-3 (LAG-3+ ) were the predominant phenotypes, indicating an immunosuppressive TME. HPV-associated tumors showed significantly higher infiltration of type I and type II conventional DCs (cDC1, cDC2) as well as several CD8+ T cell phenotypes including exhausted, activated, and proliferating T cells. On the contrary, tumors with hypoxia-associated gene signatures exhibited reduced infiltration for these immune cells. By multivariate Cox regression, immune-related prognostic factors were identified. Patient clusters defined by high infiltration of DCs and T lymphocytes combined with HPV positivity or low hypoxia showed significantly prolonged survival. Thereby, cDC1 and CD8+ T cells emerged as independent prognostic factors for local and distant recurrence. These results might contribute to the implementation of an immune cell infiltration score predicting HNSCC patients' survival and such patient stratification might improve the design of future individualized radiochemo- (immuno)therapies. [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
- View/download PDF
4. Czech Young Immunologists: Bound by Science, United in Purpose
- Author
-
Vancikova, Sabina, primary, Benešová, Iva, additional, Černý, Viktor, additional, Lázničková, Petra, additional, Miková, Eliška, additional, Šmídová, Barbora, additional, Věcek, Jan, additional, Zuani, Marco De, additional, and Niederlova, Veronika, additional
- Published
- 2023
- Full Text
- View/download PDF
5. LC coupled to ESI, MALDI and ICP MS – A multiple hyphenation for metalloproteomic studies
- Author
-
Coufalíková, Kateřina, Benešová, Iva, Vaculovič, Tomáš, Kanický, Viktor, and Preisler, Jan
- Published
- 2017
- Full Text
- View/download PDF
6. Czech Young Immunologists: Bound by science, united in purpose.
- Author
-
Vancikova, Sabina, Benešová, Iva, Černý, Viktor, Lázničková, Petra, Miková, Eliška, Šmídová, Barbora, Věcek, Jan, Zuani, Marco De, and Niederlova, Veronika
- Subjects
IMMUNOLOGISTS ,SOCIAL media ,CAREER development ,SCIENTIFIC communication - Abstract
The article discusses the establishment and activities of the Czech Young Immunologists (CYI), a group of young Czech scientists dedicated to the field of immunology. The CYI was formed in 2021 with the support of the Czech Immunology Society (CIS) and aims to create a platform for young scientists to connect and collaborate with other European societies. The CYI organizes various events, including administrative meetings, scientific meetings, and informal gatherings, both online and in-person. They also prioritize sustainability and social impact by avoiding disposable products and supporting social enterprises. The CYI plans to expand their events beyond Prague and establish collaborations with other young immunologist societies in neighboring countries. [Extracted from the article]
- Published
- 2024
- Full Text
- View/download PDF
7. Fekální mikrobiální transplantace – nová možnost ovlivnění výsledků terapie onkologických pacientů
- Author
-
Křížová, Ľudmila, primary, Benešová, Iva, additional, Petruželka, Luboš, additional, and Vočka, Michal, additional
- Published
- 2022
- Full Text
- View/download PDF
8. The Immune Contexture of Liposarcoma and Its Clinical Implications
- Author
-
Resag, Antonia, primary, Toffanin, Giulia, additional, Benešová, Iva, additional, Müller, Luise, additional, Potkrajcic, Vlatko, additional, Ozaniak, Andrej, additional, Lischke, Robert, additional, Bartunkova, Jirina, additional, Rosato, Antonio, additional, Jöhrens, Korinna, additional, Eckert, Franziska, additional, Strizova, Zuzana, additional, and Schmitz, Marc, additional
- Published
- 2022
- Full Text
- View/download PDF
9. Changes of serum protein N-glycosylation in cancer
- Author
-
Benešová, Iva, primary, Paulin Urminský, Adam, additional, Halámková, Jana, additional, and Hernychová, Lenka, additional
- Published
- 2022
- Full Text
- View/download PDF
10. Clinical Significance of Tumor-Infiltrating Conventional and Plasmacytoid Dendritic Cells in Pancreatic Ductal Adenocarcinoma
- Author
-
Plesca, Ioana, primary, Benešová, Iva, additional, Beer, Carolin, additional, Sommer, Ulrich, additional, Müller, Luise, additional, Wehner, Rebekka, additional, Heiduk, Max, additional, Aust, Daniela, additional, Baretton, Gustavo, additional, Bachmann, Michael P, additional, Feldmann, Anja, additional, Weitz, Jürgen, additional, Seifert, Lena, additional, Seifert, Adrian M, additional, and Schmitz, Marc, additional
- Published
- 2022
- Full Text
- View/download PDF
11. Microbiota as a modulator of carcinogenesis
- Author
-
Benešová, Iva, Kverka, Miloslav, and Krulová, Magdaléna
- Subjects
mikrobiální transfer ,anti-PD-1 ,microbiota transfer ,nádor ,colonisation ,imunitní checkpoint inhibitory ,tumour ,immune checkpoint inhibitors ,gut microbiota ,antibiotics ,protinádorová imunita ,antibiotika ,kolonizace ,anti-tumour immune response ,střevní mikrobiota - Abstract
Many studies show the ability of gut microbes to modulate the anti-tumour immune response by direct triggering the immune cells or by bacterial metabolites. Interestingly bacteria may even migrate to the tumour tissue and orchestrate the immune response on site. These anti-tumour effects can be improved by the administration of immune checkpoint inhibitors (ICI). Notably, some microbial effects occur only in the presence of ICI. On the contrary, microbiota may also promote tumour growth and negatively impact the effects of ICI therapy. We have disrupted the gut microbiota homeostasis by antibiotics (ATB) to study the effects of gut microbiota on the ICI. This disturbance led surprisingly to reduced tumour growth and enhanced pro-inflammatory immune response not only in the gut but also within the tumour tissue, where especially IFN-γ orchestrated the anti-tumour immune response. Importantly the anti-tumour immune response could be transferred through colonisation of germ-free mice by ATB-changed gut microbiota if concomitantly anti- programmed cell death protein 1 (αPD-1) monoclonal antibody was administrated. These mice had elevated levels of segmented filamentous bacteria (SFB), which induced systemic immune response with increased expression of IL-17 and elevated amounts of Th 17 cells,...
- Published
- 2021
12. Hodnocení kvality života a hlasu u pacientů s karcinomem hrtanu
- Author
-
Škvrňáková, Jana, Benešová, Iva, Pellant, Arnošt, Škvrňáková, Jana, Benešová, Iva, and Pellant, Arnošt
- Abstract
Cíl: Hodnocení kvality života, subjektivního vnímání změn hlasu a hlasových funkcí pomocí objektivních metod u pacientů s karcinomem hrtanu. Metodika, soubor: Průřezové kvantitativní šetření. Sběr dat proběhl pomocí dvou standardizovaných nástrojů (The World Health Organization Quality of Life Questionnaire, Voice Handicap Index) a dotazníku vlastní konstrukce. K objektivnímu měření hlasového pole byl využit systém Real Voice Lab. (RVL), k subjektivnímu hodnocení hlasu pacienty Voice handicap Index. Soubor tvořilo 30 pacientů s karcinomem hrtanu minimálně tři měsíce po léčbě, bez recidivy onemocnění. Vylučovacím kritériem byl stav po totální laryngektomii. Získaná data byla hodnocena popisnou statistikou. Výsledky: Kvalitu života pacienti hodnotili hůře v oblasti fyzického zdraví (14,47), ale v doménách prožívání (15,19), sociální vztahy (14,85), prostředí (15,4) byla kvalita života vyšší než u populace daného věkového průměru. Respondenti hodnotili hlasové obtíže jako mírné (36,3), tomu odpovídaly výsledky objektivního vyšetření hlasu (RVL). Závěry: Kvalitu života respondenti v porovnání s českou populací daného věkového průměru hodnotili hůře v oblasti fyzického zdraví, naopak v ostatních doménách byla kvalita života vyšší. Objektivní vyšetření hlasu odpovídalo subjektivnímu hodnocení hlasu pacienty. V porovnání výškových a dynamických parametrů hlasových polí s českou populací byly minimální rozdíly v normální hlasitosti a nahlas, u volání byly hodnoty pacientů výrazně nižší. Výzkumným šetřením byla vytvořena metodika objektivního vyšetření hlasu prováděné všeobecnou sestrou., Aim: Evaluation of the quality of life, subjective perception of changes in voice and vocal functions using the objective methods in patients with laryngeal cancer. Methodology: Selective quantitative survey. Data collection was performed using standardized tools (The World Health Organization Quality of Life Questionnaire, Voice Handicap Index) and a self-designed questionnaire. The Real Voice Lab (RVL) system was used to measure the voice field objectively, the subjective patients‘ evaluation of voice was done with Voice handicap Index. The research group consisted of 30 patients with laryngeal cancer, who were at least three months after their treatment and without relapse of the disease. The exclusion criteria were the condition after total laryngectomy. The obtained data were evaluated by descriptive statistics. Results: The quality of life was rated worse in the area of physical health (14.47). On the other hand, the quality of life was higher in the domains of experience (15.19), social relations (14.85) and the environment (15.4), when compared with the population of the given average age. The respondents rated the voice difficulties as moderate (36.3), which matched the results of the objective voice examination (RVL). Conclusion: The quality of life was rated worse in the area of physical health when compared to the Czech population of the given average age. On the other hand, the quality of life was higher in the other domains. The objective examination of the voice corresponded to the subjective evaluation of the voice by patients. In comparison with the height and dynamic parameters of the voice fields of the Czech population, there were minimal differences in the normal volume and the loud volume; the values set for calls were significantly lower for patients. The research investigation created a methodology for objective voice examination performed by a general nurse.
- Published
- 2021
13. Evaluation of the quality of life and voice of patients with laryngeal cancer
- Author
-
Škvrňáková, Jana, Benešová, Iva, and Pellant, Arnošt
- Subjects
kvalita života ,quality of life ,karcinom hrtanu ,hlasové funkce ,vocal functions ,laryngeal cancer - Abstract
Cíl: Hodnocení kvality života, subjektivního vnímání změn hlasu a hlasových funkcí pomocí objektivních metod u pacientů s karcinomem hrtanu. Metodika, soubor: Průřezové kvantitativní šetření. Sběr dat proběhl pomocí dvou standardizovaných nástrojů (The World Health Organization Quality of Life Questionnaire, Voice Handicap Index) a dotazníku vlastní konstrukce. K objektivnímu měření hlasového pole byl využit systém Real Voice Lab. (RVL), k subjektivnímu hodnocení hlasu pacienty Voice handicap Index. Soubor tvořilo 30 pacientů s karcinomem hrtanu minimálně tři měsíce po léčbě, bez recidivy onemocnění. Vylučovacím kritériem byl stav po totální laryngektomii. Získaná data byla hodnocena popisnou statistikou. Výsledky: Kvalitu života pacienti hodnotili hůře v oblasti fyzického zdraví (14,47), ale v doménách prožívání (15,19), sociální vztahy (14,85), prostředí (15,4) byla kvalita života vyšší než u populace daného věkového průměru. Respondenti hodnotili hlasové obtíže jako mírné (36,3), tomu odpovídaly výsledky objektivního vyšetření hlasu (RVL). Závěry: Kvalitu života respondenti v porovnání s českou populací daného věkového průměru hodnotili hůře v oblasti fyzického zdraví, naopak v ostatních doménách byla kvalita života vyšší. Objektivní vyšetření hlasu odpovídalo subjektivnímu hodnocení hlasu pacienty. V porovnání výškových a dynamických parametrů hlasových polí s českou populací byly minimální rozdíly v normální hlasitosti a nahlas, u volání byly hodnoty pacientů výrazně nižší. Výzkumným šetřením byla vytvořena metodika objektivního vyšetření hlasu prováděné všeobecnou sestrou. Aim: Evaluation of the quality of life, subjective perception of changes in voice and vocal functions using the objective methods in patients with laryngeal cancer. Methodology: Selective quantitative survey. Data collection was performed using standardized tools (The World Health Organization Quality of Life Questionnaire, Voice Handicap Index) and a self-designed questionnaire. The Real Voice Lab (RVL) system was used to measure the voice field objectively, the subjective patients‘ evaluation of voice was done with Voice handicap Index. The research group consisted of 30 patients with laryngeal cancer, who were at least three months after their treatment and without relapse of the disease. The exclusion criteria were the condition after total laryngectomy. The obtained data were evaluated by descriptive statistics. Results: The quality of life was rated worse in the area of physical health (14.47). On the other hand, the quality of life was higher in the domains of experience (15.19), social relations (14.85) and the environment (15.4), when compared with the population of the given average age. The respondents rated the voice difficulties as moderate (36.3), which matched the results of the objective voice examination (RVL). Conclusion: The quality of life was rated worse in the area of physical health when compared to the Czech population of the given average age. On the other hand, the quality of life was higher in the other domains. The objective examination of the voice corresponded to the subjective evaluation of the voice by patients. In comparison with the height and dynamic parameters of the voice fields of the Czech population, there were minimal differences in the normal volume and the loud volume; the values set for calls were significantly lower for patients. The research investigation created a methodology for objective voice examination performed by a general nurse.
- Published
- 2020
14. Pro-apoptotic and anti-apoptotic properties of mesenchymal stem cells
- Author
-
Benešová, Iva, Kössl, Jan, and Anděra, Ladislav
- Abstract
Mesenchymal stem cells (MSC) display different ways of influencing not only surroundig cells but also the function of the whole organism. Besides well known immunomodulatory properties, MSC are capable of inducing and inhibiting of apoptosis in various conditions, effecting mostly cancer and immune cells. They are able to protect other cell types against apoptosis. On the contrary, anti-apoptotic and apoptotic effect of MSC is not always beneficial. Deeper and more precise understanding of influence of MSC on the apoptosis is needed to allow the usage of MSC in the biological therapy and to facilitate the treatment of many diseases. MSC are exhibited to oxidative stress, hypoxia and many pro-apoptotic factors, which cause their senescence and apoptosis. However, without this microenvironment they will not be activated and will not gain all their properties. Nowadays is an intensive research in prolongation of MSC's lifespan done, because it would improve potential biological therapy. Key words: mesenchymal stem cells, apoptosis, biological therapy
- Published
- 2019
15. Hodnocení kvality života u pacientů s karcinomem hrtanu
- Author
-
Škvrňáková, Jana, Blanař, Vít, Benešová, Iva, Škvrňáková, Jana, Blanař, Vít, and Benešová, Iva
- Abstract
Závěrečná práce "Hodnocení kvality života u pacientů s karcinomem hrtanu" je teoreticko-výzkumná práce. Zabývá se dopady onemocnění a léčby na život pacientů s karcinomem hrtanu bez totální laryngektomie. Zaměřuje se na subjektivní hodnocení hlasu, polykání a kvalitu života pomocí standardizovaných dotazníků a zjišťuje vnímání hlasových funkcí pomocí objektivních metod., The title of thesis is "The Quality of Life of Laryngeal Cancer patiens". This theoretical and research work deals with the effects of the disease and treatment in the life of laryngeal cancer patients, without total laryngectomy. The thesis is focused on subjective voice evaluation, swallowing and quality of life, using standardised questionnaires and detects the perception of voice functions using objective methods., Fakulta zdravotnických studií, Hodnocení vedoucího: A Hodnocení oponenta: A Doplňující otázky k obhajobě: 1. Odpovídalo subjektivní hodnocení hlasových potíží (pomocí VHI) výsledkům vyšetření hlasového pole? 2. Jak by měl být organizován výzkum pro lepší porovnání těchto dvou proměnných? Obhajoba diplomové práce s prezentací výborná., Dokončená práce s úspěšnou obhajobou
- Published
- 2019
16. Hodnocení kvality života a hlasu u pacientů s karcinomem hrtanu.
- Author
-
Škvrňáková, Jana, Benešová, Iva, and Pellant, Arnošt
- Published
- 2020
17. Direct Analysis of Gold Nanoparticles from Dried Droplets Using Substrate-Assisted Laser Desorption Single Particle-ICPMS
- Author
-
Benešová, Iva, primary, Dlabková, Kristýna, additional, Zelenák, František, additional, Vaculovič, Tomáš, additional, Kanický, Viktor, additional, and Preisler, Jan, additional
- Published
- 2016
- Full Text
- View/download PDF
18. Differential Isotope Labeling of Glycopeptides for Accurate Determination of Differences in Site-Specific Glycosylation
- Author
-
Pabst, Martin, primary, Benešová, Iva, additional, Fagerer, Stephan R., additional, Jacobsen, Mathias, additional, Eyer, Klaus, additional, Schmidt, Gregor, additional, Steinhoff, Robert, additional, Krismer, Jasmin, additional, Wahl, Fabian, additional, Preisler, Jan, additional, and Zenobi, Renato, additional
- Published
- 2015
- Full Text
- View/download PDF
19. Politika zaměstnanosti v zemích Evropské unie
- Author
-
Lacina, Karel, Benešová, Iva, Lacina, Karel, and Benešová, Iva
- Abstract
Tato diplomová práce se zabývá politikou zaměstnanosti Evropské unie a jejich členských států, situací na trhu práce, vztahem ekonomického růstu a zaměstnanosti. Dále popisuje dokumenty EU v oblasti sociální politiky. Jsou zde uvedeny cíle, klíčové programy politiky zaměstnanosti, směrnice sloužící jako doporučení členským státům v boji s nezaměstnaností a hodnocení národních akčních plánů., Dokončená práce s úspěšnou obhajobou
- Published
- 2007
20. Differential Isotope Labeling of Glycopeptides for Accurate Determination of Differences in Site-Specific Glycosylation.
- Author
-
Pabst, Martin, Benešová, Iva, Fagerer, Stephan R., Jacobsen, Mathias, Eyer, Klaus, Schmidt, Gregor, Steinhoff, Robert, Krismer, Jasmin, Wahl, Fabian, Preisler, Jan, and Zenobi, Renato
- Published
- 2016
- Full Text
- View/download PDF
21. Type I conventional dendritic cells and CD8 + T cells predict favorable clinical outcome of head and neck squamous cell carcinoma patients.
- Author
-
Kirchner J, Plesca I, Rothe R, Resag A, Löck S, Benešová I, Rupp L, Linge A, Wehner R, Krause M, and Schmitz M
- Subjects
- Humans, Male, Female, Middle Aged, Aged, Lymphocytes, Tumor-Infiltrating immunology, Lymphocytes, Tumor-Infiltrating metabolism, Prognosis, Adult, Papillomavirus Infections immunology, Papillomavirus Infections complications, Papillomavirus Infections virology, Dendritic Cells immunology, Squamous Cell Carcinoma of Head and Neck immunology, Squamous Cell Carcinoma of Head and Neck virology, Squamous Cell Carcinoma of Head and Neck mortality, CD8-Positive T-Lymphocytes immunology, Tumor Microenvironment immunology, Head and Neck Neoplasms immunology, Head and Neck Neoplasms virology, Head and Neck Neoplasms mortality
- Abstract
Head and neck squamous cell carcinoma (HNSCC) is one of the most common tumor entities worldwide, with human papillomavirus (HPV) infection contributing to cancer development. Conventional therapies achieve only limited efficiency, especially in recurrent or metastatic HNSCC. As the immune landscape decisively impacts the survival of patients and treatment efficacy, this study comprehensively investigated the immunological tumor microenvironment (TME) and its association with patient outcome, with special focus on several dendritic cell (DC) and T lymphocyte subpopulations. Therefore, formalin-fixed paraffin-embedded tumor samples of 56 HNSCC patients, who have undergone resection and adjuvant radiotherapy, were analyzed by multiplex immunohistochemistry focusing on the detailed phenotypic characterization and spatial distribution of DCs, CD8
+ T cells, and T-helper cell subsets in different tumor compartments. Immune cell densities and proportions were correlated with clinical characteristics of the whole HNSCC cohort and different HPV- or hypoxia-associated subcohorts. Tumor stroma was highly infiltrated by plasmacytoid DCs and T lymphocytes. Among the T-helper cells and CD8+ T cells, stromal regulatory T cells and intraepithelial exhausted CD8+ T cells expressing programmed cell death protein-1 (PD-1+ ) and/or lymphocyte-activation gene-3 (LAG-3+ ) were the predominant phenotypes, indicating an immunosuppressive TME. HPV-associated tumors showed significantly higher infiltration of type I and type II conventional DCs (cDC1, cDC2) as well as several CD8+ T cell phenotypes including exhausted, activated, and proliferating T cells. On the contrary, tumors with hypoxia-associated gene signatures exhibited reduced infiltration for these immune cells. By multivariate Cox regression, immune-related prognostic factors were identified. Patient clusters defined by high infiltration of DCs and T lymphocytes combined with HPV positivity or low hypoxia showed significantly prolonged survival. Thereby, cDC1 and CD8+ T cells emerged as independent prognostic factors for local and distant recurrence. These results might contribute to the implementation of an immune cell infiltration score predicting HNSCC patients' survival and such patient stratification might improve the design of future individualized radiochemo-(immuno)therapies., Competing Interests: In the past 5 years, MK received funding for her research projects by Merck KGaA 2014-2018 for preclinical study; 2018-2020 for clinical study and Medipan GmbH 2014-2018. MK and AL are involved in an ongoing publicly funded German Federal Ministry of Education and Research project with the companies Medipan 2019-2022, Attomol GmbH 2019-2022, GA Generic Assays GmbH 2019-2022, Gesellschaft für medizinische und wissenschaftliche genetische Analysen 2019-2022, Lipotype GmbH 2019-2022 and PolyAn GmbH 2019-2022. MK and AL confirm that, to the best of their knowledge, none of the above-mentioned funding sources were involved in the preparation of this paper. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Kirchner, Plesca, Rothe, Resag, Löck, Benešová, Rupp, Linge, Wehner, Krause and Schmitz.)- Published
- 2024
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.