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Your search keyword '"Benenato KE"' showing total 15 results

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1. Dual mRNA therapy restores metabolic function in long-term studies in mice with propionic acidemia.

2. Accelerated Blood Clearance of Lipid Nanoparticles Entails a Biphasic Humoral Response of B-1 Followed by B-2 Lymphocytes to Distinct Antigenic Moieties.

3. mRNA Therapy Improves Metabolic and Behavioral Abnormalities in a Murine Model of Citrin Deficiency.

4. Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines.

5. Systemic mRNA Therapy for the Treatment of Fabry Disease: Preclinical Studies in Wild-Type Mice, Fabry Mouse Model, and Wild-Type Non-human Primates.

6. Systemic messenger RNA as an etiological treatment for acute intermittent porphyria.

8. A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates.

9. Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia.

10. Boosting Intracellular Delivery of Lipid Nanoparticle-Encapsulated mRNA.

11. Pharmacodynamic Profiling of a Siderophore-Conjugated Monocarbam in Pseudomonas aeruginosa: Assessing the Risk for Resistance and Attenuated Efficacy.

12. Negishi cross-coupling enabled synthesis of novel NAD(+)-dependent DNA ligase inhibitors and SAR development.

13. SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3.

14. Discovery of efficacious Pseudomonas aeruginosa-targeted siderophore-conjugated monocarbams by application of a semi-mechanistic pharmacokinetic/pharmacodynamic model.

15. Synthesis, Structure, and SAR of Tetrahydropyran-Based LpxC Inhibitors.

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