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1. Newsletter No. 10/2010

Author

J.-J. Braun, Mazen Kurban, Ralf Gutzmer, Florian Schenck, Olivier Dereure, Didac Barco, Gabor Abellan van Kan, S. Rivière, Carine Michot, F.M. Solivetti, Nicolas Meyer, Alexander A. Navarini, Agustín Alomar, Stephane Gerard, Alexander Kapp, Inan Korkmaz, J. Roewert-Huber, Daniel Haag-Wackernagel, S. Hakimi, P. Del Giudice, Josep Palou, Julide Zehra Yenin, James Signorovitch, Antoine Chartier, Anna Belloni Fortina, Ebru Celik, Wolfram Sterry, J. Dereure, Ilaria Romano, Lluís Puig, Philip J. Mease, E. Stockfleth, Toshiyuki Yamamoto, Shiraz R. Gupta, F. Elia, S. Chimenti, Uta Küttler, Andreas J. Bircher, Yanjun Bao, Angela M. Christiano, Andrew P. Yu, U. Mrowietz, A. Di Carlo, Imke Satzger, Pietro Cappugi, Yasunobu Kato, Ertugrul Egilmez, Bernard Guillot, Bruno Vellas, Louise Lovato, Benjamin Losfeld, Paula Aguilera, Lydie Guénard-Bilbault, Zafer Yonden, Gabriel Salerni, E. Berardesca, Edoardo Zattra, Tatiana Lamon, S. Gerdes, M. Teoli, M. Ulrich, Bianca Bernardini, Josep Malvehy, Yutaka Shimomura, Bernward Völker, Daniele Torchia, Susana Puig, S. Astner, Frédéric de Blay, Parvez M. Mulani, Muhammad Wajid, Ali Balci, V.A. Zahl, Cristina Carrera, Eric Q. Wu, Nese Okumus, Dan Lipsker, Laurent Balardy, Didem Didar Balci, D. Krueger-Corcoran, Ralph M. Trüeb, M. Weichenthal, C. De Mutiis, Mauro Alaibac, and A. Le Quellec

Subjects
medicine.medical_specialty, business.industry, medicine, Library science, Dermatology, business
Published
2010

2. Exceptional Bone Metastasis of Basal Cell Carcinoma in Gorlin-Goltz Syndrome

Author

Tatiana Lamon, Laurent Balardy, Gabor Abellan van Kan, Bruno Vellas, Stéphane Gérard, Benjamin Losfeld, and Nicolas Meyer

Subjects
Male, Patched Receptors, Pathology, medicine.medical_specialty, Skin Neoplasms, Basal Cell Nevus Syndrome, Pain, Bone Neoplasms, Receptors, Cell Surface, Nevoid basal-cell carcinoma syndrome, Dermatology, White People, Metastasis, medicine, Humans, Basal cell carcinoma, Neoplasm Metastasis, skin and connective tissue diseases, Malignant Skin Neoplasm, integumentary system, business.industry, fungi, Bone metastasis, Middle Aged, medicine.disease, Focal dermal hypoplasia, Focal Dermal Hypoplasia, Radiography, Falx cerebri, stomatognathic diseases, Carcinoma, Basal Cell, business
Abstract

Background: Basal cell carcinoma (BCC), the most prevalent form of cancer worldwide, is a malignant skin neoplasm. It is locally invasive, with an exceptional incidence of reported metastasis. It can also be part of the Gorlin-Goltz syndrome, an autosomal dominant genetic disorder with high penetrance and variable expressivity, which is principally characterized by cutaneous BCC, odontogenic keratocysts, palmar and/or plantar pits, and falx cerebri calcification. Observation: We report the exceptional clinical observation of a 54-year-old man presenting bone metastasis from BCC in Gorlin-Goltz syndrome. Conclusion: Less than 300 cases of metastatic BCC have been reported in the literature. The present case is the second associated with Gorlin-Goltz syndrome.

Published
2009

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