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2. Use of Allium® ureteral stents: Functional and surgical outcomes

Author

Litterio, G., primary, Nicolai, M., additional, Berardinelli, F., additional, Ciavarella, D., additional, De Palma, A., additional, Ferretti, S., additional, Orsini, A., additional, Basconi, M., additional, Cicchetti, R., additional, Tamborino, F., additional, Falcone, A., additional, Marchioni, M., additional, and Schips, L., additional

Published
2024
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10. Progression-free survival as surrogate endpoint in high-risk non-muscle invasive bladder cancer studies: results from a machine learning-based analysis of a large multi-institutional database

Author

Marchioni, M., primary, Porreca, A., additional, Di Nicola, M., additional, Lucarelli, G., additional, Dorin, V.M., additional, Soria, F., additional, Terracciano, D., additional, Mistretta, F.A., additional, Buonerba, C., additional, Cantiello, F., additional, Mari, A., additional, Minervini, A., additional, Veccia, A., additional, Musi, G., additional, Hurle, R., additional, Busetto, G.M., additional, Del Giudice, F., additional, Chung, B.I., additional, Berardinelli, F., additional, Perdonà, S., additional, Del Prete, P., additional, Mirone, V., additional, Borghesi, M., additional, Bove, P., additional, Autorino, R., additional, Crisan, N., additional, Battaglia, M., additional, Ditonno, P., additional, Russo, G.I., additional, Muto, M., additional, Damiano, R., additional, Porpiglia, F., additional, de Cobelli, O., additional, Schips, L., additional, and Ferro, M., additional

Published
2022
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17. Nomogram for predicting the likelihood of postoperative surgical complications in patients treated with partial nephrectomy: a prospective multicentre observational study (the RECORd 2 project)

Author

Mari, A., Campi, R., Schiavina, R., Amparore, D., Antonelli, A., Artibani, W., Barale, M., Bertini, R., Borghesi, M., Bove, P., Brunocilla, E., Capitanio, U., Da Pozzo, L., Daja, J., Gontero, P., Larcher, A., Li Marzi, V., Longo, N., Mirone, V., Montanari, E., Pisano, F., Porpiglia, F., Simeone, C., Siracusano, S., Tellini, R., Trombetta, C., Volpe, A., Ficarra, V., Carini, M., Minervini, A., Altieri, V., Berardinelli, F., Celia, A., Costantini, E., Di Maida, F., Falsaperla, M., Fiori, C., Furlan, M., Marson, F., Montorsi, F., Morgia, G., Porreca, A., Roscigno, M., Schips, L., Selli, C., Simonato, A., Terrone, C., Vespasiani, G., Villari, D., Mari A, Campi R, Schiavina R, Amparore D, Antonelli A, Artibani W, Barale M, Bertini R, Borghesi M, Bove P, Brunocilla E, Capitanio U, Da Pozzo L, Daja J, Gontero P, Larcher A, Li Marzi V, Longo N, Mirone V, Montanari E, Pisano F, Porpiglia F, Simeone C, Siracusano S, Tellini R, Trombetta C, Volpe A, Ficarra V, Carini M, Minervini A, Mari, Andrea, Campi, Riccardo, Schiavina, Riccardo, Amparore, Daniele, Antonelli, Alessandro, Artibani, Walter, Barale, Maurizio, Bertini, Roberto, Borghesi, Marco, Bove, Pierluigi, Brunocilla, Eugenio, Capitanio, Umberto, Da Pozzo, Luigi, Daja, Julian, Gontero, Paolo, Larcher, Alessandro, Li Marzi, Vincenzo, Longo, Nicola, Mirone, Vincenzo, Montanari, Emanuele, Pisano, Francesca, Porpiglia, Francesco, Simeone, Claudio, Siracusano, Salvatore, Tellini, Riccardo, Trombetta, Carlo, Volpe, Alessandro, Ficarra, Vincenzo, Carini, Marco, Minervini, Andrea, Mari, A., Campi, R., Schiavina, R., Amparore, D., Antonelli, A., Artibani, W., Barale, M., Bertini, R., Borghesi, M., Bove, P., Brunocilla, E., Capitanio, U., Da Pozzo, L., Daja, J., Gontero, P., Larcher, A., Li Marzi, V., Longo, N., Mirone, V., Montanari, E., Pisano, F., Porpiglia, F., Simeone, C., Siracusano, S., Tellini, R., Trombetta, C., Volpe, A., Ficarra, V., Carini, M., Minervini, A., Altieri, V., Berardinelli, F., Celia, A., Costantini, E., Di Maida, F., Falsaperla, M., Fiori, C., Furlan, M., Marson, F., Montorsi, F., Morgia, G., Porreca, A., Roscigno, M., Schips, L., Selli, C., Simonato, A., Terrone, C., Vespasiani, G., Villari, D., Mari, A, Campi, R, Schiavina, R, Amparore, D, Antonelli, A, Artibani, W, Barale, M, Bertini, R, Borghesi, M, Bove, P, Brunocilla, E, Capitanio, U, Da Pozzo, L, Daja, J, Gontero, P, Larcher, A, Li Marzi, V, Longo, N, Mirone, V, Montanari, E, Pisano, F, Porpiglia, F, Simeone, C, Siracusano, S, Tellini, R, Trombetta, C, Volpe, A, Ficarra, V, Carini, M, Minervini, A, Altieri, V, Berardinelli, F, Celia, A, Costantini, E, Di Maida, F, Falsaperla, M, Fiori, C, Furlan, M, Marson, F, Montorsi, F, Morgia, G, Porreca, A, Roscigno, M, Schips, L, Selli, C, Simonato, A, Terrone, C, Vespasiani, G, and Villari, D

Subjects
partial nephrectomy, complications, Male, medicine.medical_specialty, renal cell carcinoma, nephron-sparing surgery, nomogram, robot-assisted partial nephrectomy, medicine.medical_treatment, Urology, 030232 urology & nephrology, complication, Logistic regression, Nephrectomy, 03 medical and health sciences, 0302 clinical medicine, Postoperative Complications, Interquartile range, Renal cell carcinoma, complications, nephron-sparing surgery, nomogram, partial nephrectomy, renal cell carcinoma, robot-assisted partial nephrectomy, Medicine, Humans, In patient, Prospective Studies, Stage (cooking), Aged, business.industry, Nomogram, postoperative surgical complications, partial nephrectomy, RECORd 2 project, Kidney Neoplasm, Nomogram, Middle Aged, medicine.disease, Kidney Neoplasms, Surgery, Editorial Commentary, Nomograms, Settore MED/24, 030220 oncology & carcinogenesis, partial nephrectomy, complications, Observational study, Female, Postoperative Complication, business, Human
Abstract

Objective To identify meaningful predictors and to develop a nomogram of postoperative surgical complications in patients treated with partial nephrectomy (PN). Patients and methods We prospectively evaluated 4308 consecutive patients who had surgical treatment for renal tumours, between 2013 and 2016, at 26 Italian urological centres (RECORd 2 project). A multivariable logistic regression for surgical complications was performed. A nomogram was created from the multivariable model. Internal validation processes were performed using bootstrapping with 1000 repetitions. Results Overall, 2584 patients who underwent PN were evaluated for the final analyses. The median (interquartile [IQR]) American Society of Anesthesiologists (ASA) score was 2 (2-3). In all, 72.4% of patients had clinical T1a (cT1a) stage tumours. The median (IQR) Preoperative Aspects and Dimensions Used for an Anatomical (PADUA) score was 7 (6-8). Overall, 34.3%, 27.7%, 38% of patients underwent open PN (OPN), laparoscopic PN (LPN), and robot-assisted PN (RAPN). Overall and major postoperative surgical complications were recorded in 10.2% and 2.5% of patients, respectively. At multivariable analysis, age, ASA score, cT2 vs cT1a stage, PADUA score, preoperative anaemia, OPN and LPN vs RAPN, were significant predictive factors of postoperative surgical complications. We used these variables to construct a nomogram for predicting the risk of postoperative surgical complications. At decision curve analysis, the nomogram led to superior outcomes for any decision associated with a threshold probability of >5%. Conclusion Several clinical predictors have been associated with postoperative surgical complications after PN. We used this information to develop and internally validate a nomogram to predict such risk.

Published
2019

18. Nomogram for predicting the likelihood of postoperative surgical complications in patients treated with partial nephrectomy: a prospective multicentre observational study (the RECORd 2 project)

Author

Mari, A, Campi, R, Schiavina, R, Amparore, D, Antonelli, A, Artibani, W, Barale, M, Bertini, R, Borghesi, M, Bove, P, Brunocilla, E, Capitanio, U, Da Pozzo, L, Daja, J, Gontero, P, Larcher, A, Li Marzi, V, Longo, N, Mirone, V, Montanari, E, Pisano, F, Porpiglia, F, Simeone, C, Siracusano, S, Tellini, R, Trombetta, C, Volpe, A, Ficarra, V, Carini, M, Minervini, A, Altieri, V, Berardinelli, F, Celia, A, Costantini, E, Di Maida, F, Falsaperla, M, Fiori, C, Furlan, M, Marson, F, Montorsi, F, Morgia, G, Porreca, A, Roscigno, M, Schips, L, Selli, C, Simonato, A, Terrone, C, Vespasiani, G, Villari, D, Mari A., Campi R., Schiavina R., Amparore D., Antonelli A., Artibani W., Barale M., Bertini R., Borghesi M., Bove P., Brunocilla E., Capitanio U., Da Pozzo L., Daja J., Gontero P., Larcher A., Li Marzi V., Longo N., Mirone V., Montanari E., Pisano F., Porpiglia F., Simeone C., Siracusano S., Tellini R., Trombetta C., Volpe A., Ficarra V., Carini M., Minervini A., Altieri V., Berardinelli F., Celia A., Costantini E., Di Maida F., Falsaperla M., Fiori C., Furlan M., Marson F., Montorsi F., Morgia G., Porreca A., Roscigno M., Schips L., Selli C., Simonato A., Terrone C., Vespasiani G., Villari D., Mari, A, Campi, R, Schiavina, R, Amparore, D, Antonelli, A, Artibani, W, Barale, M, Bertini, R, Borghesi, M, Bove, P, Brunocilla, E, Capitanio, U, Da Pozzo, L, Daja, J, Gontero, P, Larcher, A, Li Marzi, V, Longo, N, Mirone, V, Montanari, E, Pisano, F, Porpiglia, F, Simeone, C, Siracusano, S, Tellini, R, Trombetta, C, Volpe, A, Ficarra, V, Carini, M, Minervini, A, Altieri, V, Berardinelli, F, Celia, A, Costantini, E, Di Maida, F, Falsaperla, M, Fiori, C, Furlan, M, Marson, F, Montorsi, F, Morgia, G, Porreca, A, Roscigno, M, Schips, L, Selli, C, Simonato, A, Terrone, C, Vespasiani, G, Villari, D, Mari A., Campi R., Schiavina R., Amparore D., Antonelli A., Artibani W., Barale M., Bertini R., Borghesi M., Bove P., Brunocilla E., Capitanio U., Da Pozzo L., Daja J., Gontero P., Larcher A., Li Marzi V., Longo N., Mirone V., Montanari E., Pisano F., Porpiglia F., Simeone C., Siracusano S., Tellini R., Trombetta C., Volpe A., Ficarra V., Carini M., Minervini A., Altieri V., Berardinelli F., Celia A., Costantini E., Di Maida F., Falsaperla M., Fiori C., Furlan M., Marson F., Montorsi F., Morgia G., Porreca A., Roscigno M., Schips L., Selli C., Simonato A., Terrone C., Vespasiani G., and Villari D.

Abstract

Objective: To identify meaningful predictors and to develop a nomogram of postoperative surgical complications in patients treated with partial nephrectomy (PN). Patients and Methods: We prospectively evaluated 4308 consecutive patients who had surgical treatment for renal tumours, between 2013 and 2016, at 26 Italian urological centres (RECORd 2 project). A multivariable logistic regression for surgical complications was performed. A nomogram was created from the multivariable model. Internal validation processes were performed using bootstrapping with 1000 repetitions. Results: Overall, 2584 patients who underwent PN were evaluated for the final analyses. The median (interquartile [IQR]) American Society of Anesthesiologists (ASA) score was 2 (2–3). In all, 72.4% of patients had clinical T1a (cT1a) stage tumours. The median (IQR) Preoperative Aspects and Dimensions Used for an Anatomical (PADUA) score was 7 (6–8). Overall, 34.3%, 27.7%, 38% of patients underwent open PN (OPN), laparoscopic PN (LPN), and robot-assisted PN (RAPN). Overall and major postoperative surgical complications were recorded in 10.2% and 2.5% of patients, respectively. At multivariable analysis, age, ASA score, cT2 vs cT1a stage, PADUA score, preoperative anaemia, OPN and LPN vs RAPN, were significant predictive factors of postoperative surgical complications. We used these variables to construct a nomogram for predicting the risk of postoperative surgical complications. At decision curve analysis, the nomogram led to superior outcomes for any decision associated with a threshold probability of >5%. Conclusion: Several clinical predictors have been associated with postoperative surgical complications after PN. We used this information to develop and internally validate a nomogram to predict such risk.

Published
2019

19. Perioperative Outcomes of Open, Laparoscopic, and Robotic Partial Nephrectomy: A Prospective Multicenter Observational Study (The RECORd 2 Project)

Author

Bravi, C. A., Larcher, A., Capitanio, U., Mari, A., Antonelli, A., Artibani, W., Barale, M., Bertini, R., Bove, P., Brunocilla, E., Da Pozzo, L., Di Maida, F., Fiori, C., Gontero, P., Li Marzi, V., Longo, N., Mirone, V., Montanari, E., Porpiglia, F., Schiavina, R., Schips, L., Simeone, C., Siracusano, S., Terrone, C., Trombetta, C., Volpe, A., Montorsi, F., Ficarra, V., Carini, M., Minervini, A., Altieri, V., Berardinelli, F., Borghesi, M., Celia, A., Cindolo, L., Costantini, E., Daja, J., Falsaperla, M., Furlan, M., Morgia, G., Porreca, A., Roscigno, M., Selli, C., Simonato, A., Tellini, R., Vespasiani, G., Villari, D., Bravi, C, Larcher, A, Capitanio, U, Mari, A, Antonelli, A, Artibani, W, Barale, M, Bertini, R, Bove, P, Brunocilla, E, Da Pozzo, L, Di Maida, F, Fiori, C, Gontero, P, Li Marzi, V, Longo, N, Mirone, V, Montanari, E, Porpiglia, F, Schiavina, R, Schips, L, Simeone, C, Siracusano, S, Terrone, C, Trombetta, C, Volpe, A, Montorsi, F, Ficarra, V, Carini, M, Minervini, A, Bravi, C. A., Larcher, A., Capitanio, U., Mari, A., Antonelli, A., Artibani, W., Barale, M., Bertini, R., Bove, P., Brunocilla, E., Da Pozzo, L., Di Maida, F., Fiori, C., Gontero, P., Li Marzi, V., Longo, N., Mirone, V., Montanari, E., Porpiglia, F., Schiavina, R., Schips, L., Simeone, C., Siracusano, S., Terrone, C., Trombetta, C., Volpe, A., Montorsi, F., Ficarra, V., Carini, M., Minervini, A., and Bravi CA, Larcher A, Capitanio U, Mari A, Antonelli A, Artibani W, Barale M, Bertini R, Bove P, Brunocilla E, Da Pozzo L, Di Maida F, Fiori C, Gontero P, Li Marzi V, Longo N, Mirone V, Montanari E, Porpiglia F, Schiavina R, Schips L, Simeone C, Siracusano S, Terrone C, Trombetta C, Volpe A, Montorsi F, Ficarra V, Carini M, Minervini A

Subjects
Male, medicine.medical_specialty, Urology, medicine.medical_treatment, 030232 urology & nephrology, Acute kidney injury, Laparoscopy, Partial nephrectomy, Perioperative outcomes, Renal cell carcinoma, Robotic surgery, Trifecta, Nephrectomy, 03 medical and health sciences, 0302 clinical medicine, Robotic Surgical Procedures, Ischemia, Medicine, Humans, Minimally Invasive Surgical Procedures, Prospective Studies, Perioperative Period, Aged, medicine.diagnostic_test, business.industry, renal carcinoma, Odds ratio, Perioperative, Middle Aged, medicine.disease, Confidence interval, Kidney Neoplasms, Surgery, Settore MED/24, 030220 oncology & carcinogenesis, Female, Acute kidney injury, Laparoscopy, Partial nephrectomy, Perioperative outcomes, Renal cell carcinoma, Robotic surgery, Trifecta, business, Perioperative outcome
Abstract

Background: Partial nephrectomy (PN) has a non-negligible perioperative morbidity. Comparative evidence of the available surgical techniques is limited. Objective: To compare the perioperative outcomes of open, laparoscopic, and robotic PN. Methods: Data of 2331 patients treated with PN for cT1 renal tumors were extracted from the RECORd2 database, a prospective multicenter project. Multivariable regression models assessed the relationship between surgical technique and surgical margins, warm ischemia time, postoperative complications, and acute kidney injury (AKI). The probability of achieving a modified trifecta (negative margins, warm ischemia time

Published
2021

21. Effects of the combined treatment with a g‐quadruplex‐stabilizing ligand and photon beams on glioblastoma stem‐like cells: A magnetic resonance study

Author

Palma, A., Grande, S., Luciani, A. M., Ricci-vitiani, L., Buccarelli, M., Pallini, Roberto, Triveri, A., Pirota, V., Doria, F., D'Alessandris, Quintino Giorgio, Berardinelli, F., Antoccia, A., Rosi, A., Pallini R. (ORCID:0000-0002-4611-8827), D'alessandris Q. G. (ORCID:0000-0002-2953-9291), Palma, A., Grande, S., Luciani, A. M., Ricci-vitiani, L., Buccarelli, M., Pallini, Roberto, Triveri, A., Pirota, V., Doria, F., D'Alessandris, Quintino Giorgio, Berardinelli, F., Antoccia, A., Rosi, A., Pallini R. (ORCID:0000-0002-4611-8827), and D'alessandris Q. G. (ORCID:0000-0002-2953-9291)

Abstract

Glioblastoma multiforme is a malignant primary brain tumor with a poor prognosis and high rates of chemo‐radiotherapy failure, mainly due to a small cell fraction with stem‐like properties (GSCs). The mechanisms underlying GSC response to radiation need to be elucidated to enhance sensitivity to treatments and to develop new therapeutic strategies. In a previous study, two GSC lines, named line #1 and line #83, responded differently to carbon ions and photon beams, with the differences likely attributable to their own different metabolic fingerprint rather than to radiation type. Data from the literature showed the capability of RHPS4, a G‐quadruplex stabilizing ligand, to sensitize the glioblastoma radioresistant U251MG cells to X‐rays. The combined metabolic effect of ligand #190, a new RHPS4‐derivative showing reduced cardiotoxicity, and a photon beam has been monitored by magnetic resonance (MR) spectroscopy for the two GSC lines, #1 and #83, to reveal whether a synergistic response occurs. MR spectra from both lines were affected by single and combined treatments, but the variations of the analysed metabolites were statistically significant mainly in line #1, without synergistic effects due to combination. The multivariate analysis of ten metabolites shows a separation between control and treated samples in line #1 regardless of treatment type, while separation was not detected in line #83.

Published
2021

23. PD-0667: Early analysis from two phase I trials on SBRT of isolated nodal recurrences in prostate patients

Author

Deodato, F., primary, Re, A., additional, Ianiro, A., additional, Ferro, M., additional, Macchia, G., additional, Picardi, V., additional, Boccardi, M., additional, Buwenge, M., additional, Assalone, P., additional, Berardinelli, F., additional, Maselli, G., additional, Cammelli, S., additional, Romano, C., additional, Mignogna, S., additional, Valentini, V., additional, Morganti, A.G., additional, and Cilla, S., additional

Published
2020
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25. SC221 - Progression-free survival as surrogate endpoint in high-risk non-muscle invasive bladder cancer studies: results from a machine learning-based analysis of a large multi-institutional database

Author

Marchioni, M., Porreca, A., Di Nicola, M., Lucarelli, G., Dorin, V.M., Soria, F., Terracciano, D., Mistretta, F.A., Buonerba, C., Cantiello, F., Mari, A., Minervini, A., Veccia, A., Musi, G., Hurle, R., Busetto, G.M., Del Giudice, F., Chung, B.I., Berardinelli, F., Perdonà, S., Del Prete, P., Mirone, V., Borghesi, M., Bove, P., Autorino, R., Crisan, N., Battaglia, M., Ditonno, P., Russo, G.I., Muto, M., Damiano, R., Porpiglia, F., de Cobelli, O., Schips, L., and Ferro, M.

Published
2022
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26. The effect of obesity and overweight status on complications and survival after minimally invasive kidney surgery in patients with clinical T2 renal masses: Evidences from rosula dataset

Author

Berardinelli, F., primary, Marchioni, M., additional, De Francesco, P., additional, Simone, G., additional, Minervini, A., additional, Perdona, S., additional, Capitanio, U., additional, Ferro, M., additional, Amparone, D., additional, Eun, D., additional, Porter, J., additional, Rha, K., additional, Mottrie, A., additional, White, W., additional, Yang, B., additional, Jacobsohn, K., additional, Uzzo, R., additional, Challacombe, B., additional, Antonio, D., additional, Tuderti, G., additional, Costantini, M., additional, Mari, A., additional, Carini, M., additional, Quarto, G., additional, Larcher, A., additional, De Cobelli, O., additional, De Luyk, N., additional, Sundaram, C., additional, Cindolo, L., additional, Spinozzi, L., additional, Castellucci, R., additional, Haber, G., additional, Montorsi, F., additional, Derweesh, I., additional, Gallucci, M., additional, Kaouk, J., additional, Portpiglia, F., additional, Autorino, R., additional, and Schips, L., additional

Published
2019
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32. Outcomes of laparoscopic and robotic surgery for clinical T2 renal masses in obese patients: A multicenter international study

Author

Berardinelli, F., primary, Marchioni, M., additional, De Francesco, P., additional, Simone, G., additional, Minervini, A., additional, Perdona, S., additional, Capitanio, U., additional, Ferro, M., additional, Amparore, D., additional, Eun, D., additional, Porter, J., additional, Rha, K., additional, Mottrie, A., additional, White, W., additional, Yang, B., additional, Jacobsohn, K., additional, Uzzo, R., additional, Challacombe, B., additional, Tuderti, G., additional, Costantini, M., additional, Mari, A., additional, Carini, M., additional, Quarto, G., additional, Larcher, A., additional, de Cobelli, O., additional, De Luyk, N., additional, Sundaram, C., additional, Cindolo, L., additional, Castellan, P., additional, Castellucci, R., additional, Haber, G., additional, Montorsi, F., additional, Derweesh, I., additional, Gallucci, M., additional, Kaouk, J., additional, Porpiglia, F., additional, Autorino, R., additional, and Schips, L., additional

Published
2018
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35. Perioperative, functional and oncological outcomes of robot-assisted partial nephrectomy for cT2 renal tumors: A multicenter analysis (The ROSULA project)

Author

Bertolo, R.G., primary, Autorino, R., additional, Derweesh, I., additional, Porter, J., additional, Liao, M., additional, Anele, U., additional, Hampton, L., additional, Larcher, A., additional, Capitanio, U., additional, Gallucci, M., additional, Simone, G., additional, Minervini, A., additional, Carini, M., additional, Mari, A., additional, Eun, D., additional, Keehn, A., additional, Perdonà, S., additional, Quarto, G., additional, Ferro, M., additional, Mottrie, A., additional, De Naeyer, G., additional, Chang, K., additional, Rha, K., additional, Uzzo, R., additional, Kutikov, A., additional, Chen, D., additional, Smaldone, M., additional, Schips, L., additional, Berardinelli, F., additional, White, W., additional, Yang, B., additional, Zang, C., additional, Jacobsohn, K., additional, Langenstroer, P., additional, Dasgupta, P., additional, De Luyk, N., additional, Challacombe, B., additional, Kilday, P., additional, Lau, C., additional, Garisto Risco, J.D., additional, Kaouk, J., additional, Sanduram, C., additional, Sulek, J., additional, Ashrafi, A., additional, Aron, M., additional, Gill, I., additional, and Porpiglia, F., additional

Published
2018
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39. SC55 - The effect of obesity and overweight status on complications and survival after minimally invasive kidney surgery in patients with clinical T2 renal masses: Evidences from rosula dataset

Author

Berardinelli, F., Marchioni, M., De Francesco, P., Simone, G., Minervini, A., Perdona, S., Capitanio, U., Ferro, M., Amparone, D., Eun, D., Porter, J., Rha, K., Mottrie, A., White, W., Yang, B., Jacobsohn, K., Uzzo, R., Challacombe, B., Antonio, D., Tuderti, G., Costantini, M., Mari, A., Carini, M., Quarto, G., Larcher, A., De Cobelli, O., De Luyk, N., Sundaram, C., Cindolo, L., Spinozzi, L., Castellucci, R., Haber, G., Montorsi, F., Derweesh, I., Gallucci, M., Kaouk, J., Portpiglia, F., Autorino, R., and Schips, L.

Published
2019
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42. Status report of a systematic investigation on low-dose ionizing radiation effects in mammalian cells

Author

Cherubini R, De Nadal, V, Gerardi S, Guryev D, Antoccia A, Berardinelli F, Tanzarella C., SGURA, Antonella, Cherubini, R, De, Nadal, V, Gerardi, S, Guryev, D, Antoccia, A, Berardinelli, F, Sgura, Antonella, and Tanzarella, C.

Subjects
V79 CELLS, INCREASED RADIORESISTANCE, LOW-ENERGY PROTONS
Abstract

In the last 15 years a growing interest in the biological effects induced by low doses of ionizing ratiation has arisen in the scientific community, due to an increasing number of experimental evidences showing a plethora of non-linear effects occuring after low-dose irradiations. In particular, hyper-radiosensitivity and induced radioresistance (HRS/IRR) have been reported after exposure to low- and high-LET radiation, in human (normal and tumoural) and other mammalian cells in vitro. In this framework, Chinese hamster V79 cells, human primary fibroblasts (HFFF2) and murine embryonic fibroblast's (MEFs) were irradiated with broad-beams beams of protons in the dose range 0.1-5.0Gy and at 1 Gy/min dose-rate. Cellular response has been evaluated in terms of cell survival, micronuclei induction, chromosomal aberrations and telomere length alterations. For comparison purpose, the same end-points were studied after X/gamma-rays irradiation.

Published
2008

43. Retrograde intrarenal surgery in the elderly: Is it feasible and safe?

Author

Berardinelli, F., primary, De Francesco, P., additional, Marchioni, M., additional, Cera, N., additional, Proietti, S., additional, Hennessey, D., additional, Dalpiaz, O., additional, Cracco, C., additional, Scoffone, C., additional, Giusti, G., additional, Cindolo, L., additional, and Schips, L., additional

Published
2017
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44. The adherence to the EAU Guidelines on penile cancer treatment could influence the survival: Multicenter, retrospective study

Author

Cindolo, L., primary, Bada, M., additional, Nyirády, P., additional, Varga, J., additional, Ditonno, P., additional, Boccasile, S., additional, Battaglia, M., additional, Chiodini, P., additional, Berardinelli, F., additional, De Nunzio, C., additional, Tema, G., additional, Veccia, A., additional, Antonelli, A., additional, Simeone, C., additional, Puliatti, S., additional, Micali, S., additional, and Schips, L., additional

Published
2017
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48. P143 - Outcomes of laparoscopic and robotic surgery for clinical T2 renal masses in obese patients: A multicenter international study

Author

Berardinelli, F., Marchioni, M., De Francesco, P., Simone, G., Minervini, A., Perdona, S., Capitanio, U., Ferro, M., Amparore, D., Eun, D., Porter, J., Rha, K., Mottrie, A., White, W., Yang, B., Jacobsohn, K., Uzzo, R., Challacombe, B., Tuderti, G., Costantini, M., Mari, A., Carini, M., Quarto, G., Larcher, A., de Cobelli, O., De Luyk, N., Sundaram, C., Cindolo, L., Castellan, P., Castellucci, R., Haber, G., Montorsi, F., Derweesh, I., Gallucci, M., Kaouk, J., Porpiglia, F., Autorino, R., and Schips, L.

Published
2018
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50. An immunosurveillance mechanism controls cancer cell ploidy

Author

Senovilla L, Vitale I, Martins I, Tailler M, Pailleret C, Michaud M, Galluzzi L, Adjemian S, Kepp O, Niso-Santano M, Shen S, Marixf1o G, Criollo A, Boilxe8ve A, Job B, Ladoire S, Ghiringhelli F, Sistigu A, Yamazaki T, Rello-Varona S, Locher C, Poirier-Colame V, Talbot M, Valent A, Berardinelli F, Antoccia A, Ciccosanti F, Fimia GM, Piacentini M, Fueyo A, Messina NL, Li M, Chan CJ, Sigl V, Pourcher G, Ruckenstuhl C, Carmona-Gutierrez D, Lazar V, Penninger JM, Madeo F, Lxf3pez-Otxedn C, Smyth MJ, Zitvogel L, and Castedo

Published
2012

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