345 results on '"Bertamino, Alessia"'
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2. Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization
3. New TRPM8 blockers exert anticancer activity over castration-resistant prostate cancer models
4. Development and application of a fast ultra-high performance liquid chromatography-trapped ion mobility mass spectrometry method for untargeted lipidomics
5. Neuroprotective Potential of Indole-Based Compounds: A Biochemical Study on Antioxidant Properties and Amyloid Disaggregation in Neuroblastoma Cells.
6. Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification
7. Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization
8. Exploring Endocannabinoid System: Unveiling New Roles in Modulating ER Stress.
9. In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel
10. Therapeutic potential of TRPM8 antagonists in prostate cancer
11. Immunomodulatory activity of Humulus lupulus bitter acids fraction: Enhancement of natural killer cells function by NKp44 activating receptor stimulation
12. Identification of an indol-based multi-target kinase inhibitor through phenotype screening and target fishing using inverse virtual screening approach
13. Voltage-Gated K + Channel Modulation by Marine Toxins: Pharmacological Innovations and Therapeutic Opportunities.
14. KCNT1 Channel Blockers: A Medicinal Chemistry Perspective.
15. Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening
16. Investigation on side-product formation during the synthesis of a lactoferrin-derived lactam-bridged cyclic peptide
17. Salicylic Acid Release from Syndiotactic Polystyrene Staple Fibers
18. Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis
19. On the modulation of TRPM channels: Current perspectives and anticancer therapeutic implications
20. Antiangiogenic Effects of Natural Compounds in Hepatic Inflammation
21. Dihydrithieno[2,3-b]naphto-4,9-dione analogues as anticancer agents: Synthesis and in cell pharmacological studies
22. On the modulation of TRPM channels: Current perspectives and anticancer therapeutic implications
23. Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis
24. Peptidomimetics as Potentdual SARS-CoV-2 Cathepsin-L and Main Protease Inhibitors: In Silico Design, Synthesis and Pharmacological Characterization
25. In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents
26. New Frontiers on ER Stress Modulation: Are TRP Channels the Leading Actors?
27. CaMKII protects MKP-1 from proteasome degradation in endothelial cells
28. Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization
29. Design, synthesis and efficacy of novel G protein-coupled receptor kinase 2 inhibitors
30. Characterization of a selective CaMKII peptide inhibitor
31. Anti-Angiogenic Effects of Natural Compounds in Diet-Associated Hepatic Inflammation.
32. Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK
33. Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity
34. MALDI Mass Spectrometry Imaging Highlights Specific Metabolome and Lipidome Profiles in Salivary Gland Tumor Tissues
35. In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening
36. N-4 Alkyl Cytosine Derivatives Synthesis: A New Approach
37. New TRPM8 Blockers Exert Anticancer Activity Over Castration-Resistant Prostate Cancer Models
38. In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents.
39. Discovery of a Novel Tetrapeptide against Influenza A Virus: Rational Design, Synthesis, Bioactivity Evaluation and Computational Studies
40. Characterization of phase I and phase II metabolites of hop (Humulus lupulus L.) bitter acids: In vitro and in vivo metabolic profiling by UHPLC-Q-Orbitrap
41. A New Approach to the Synthesis of Policyclic Dipeptide Derivatives as Potential Antitumoral Agents
42. Combinatorial Approach in the Synthesis of a Small Library of β-Turn Structures Based on Thiazolidine Moiety
43. A novel approach to the synthesis of diaza-bridged heterocycle derivatives
44. Bioactive Polyphenols from Pomegranate Juice Reduce 5-Fluorouracil-Induced Intestinal Mucositis in Intestinal Epithelial Cells
45. Exploration of TRPM8 Binding Sites by β-Carboline-Based Antagonists and Their In Vitro Characterization and In Vivo Analgesic Activities
46. Pharmacological inhibition of GRK2 improves cardiac metabolism and function in experimental heart failure
47. A novel quinone–based derivative (DTNQ–Pro) induces apoptotic death via modulation of heat shock protein expression in Caco–2 cells
48. Synthesis and Pharmacological Evaluation of Analogs of Indole-Based Cannabimimetic Agents
49. A New Series of 1,3-Dihidro-Imidazo[1,5-c]thiazole-5,7-Dione Derivatives: Synthesis and Interaction with Aβ(25-35) Amyloid Peptide
50. Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitroand In VivoAnti-Inflammatory Characterization
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