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826 results on '"Bertoletti, Antonio"'

5. G9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered T cells against hepatocellular carcinoma

Author

Lam, Maxine S. Y., Reales-Calderon, Jose Antonio, Ow, Jin Rong, Aw, Joey J. Y., Tan, Damien, Vijayakumar, Ragavi, Ceccarello, Erica, Tabaglio, Tommaso, Lim, Yan Ting, Chien, Wang Loo, Lai, Fritz, Tanoto, Anthony Tan, Chen, Qingfeng, Sobota, Radoslaw M., Adriani, Giulia, Bertoletti, Antonio, Guccione, Ernesto, and Pavesi, Andrea

Published
2023
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6. Rapid, scalable assessment of SARS-CoV-2 cellular immunity by whole-blood PCR

Author

Schwarz, Megan, Torre, Denis, Lozano-Ojalvo, Daniel, Tan, Anthony T., Tabaglio, Tommaso, Mzoughi, Slim, Sanchez-Tarjuelo, Rodrigo, Le Bert, Nina, Lim, Joey Ming Er, Hatem, Sandra, Tuballes, Kevin, Camara, Carmen, Lopez-Granados, Eduardo, Paz-Artal, Estela, Correa-Rocha, Rafael, Ortiz, Alberto, Lopez-Hoyos, Marcos, Portoles, Jose, Cervera, Isabel, Gonzalez-Perez, Maria, Bodega-Mayor, Irene, Conde, Patricia, Oteo-Iglesias, Jesús, Borobia, Alberto M., Carcas, Antonio J., Frías, Jesús, Belda-Iniesta, Cristóbal, Ho, Jessica S. Y., Nunez, Kemuel, Hekmaty, Saboor, Mohammed, Kevin, Marsiglia, William M., Carreño, Juan Manuel, Dar, Arvin C., Berin, Cecilia, Nicoletti, Giuseppe, Della Noce, Isabella, Colombo, Lorenzo, Lapucci, Cristina, Santoro, Graziano, Ferrari, Maurizio, Nie, Kai, Patel, Manishkumar, Barcessat, Vanessa, Gnjatic, Sacha, Harris, Jocelyn, Sebra, Robert, Merad, Miriam, Krammer, Florian, Kim-schulze, Seunghee, Marazzi, Ivan, Bertoletti, Antonio, Ochando, Jordi, and Guccione, Ernesto

Published
2022
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8. SAT-383 Rapid analysis of HBV-specific T cell secretomes reveals distinct antiviral immune profiles among chronic HBV patients

Author

Bert, Nina Le, primary, Koffas, Apostolos, additional, Tan, Anthony, additional, Kumar, Rajneesh, additional, Mak, Lung-Yi, additional, Miao, Tizong, additional, Lei, Yu, additional, Hariharaputran, Smrithi, additional, Hang, Shou Kit, additional, Guo, Yifei, additional, Chen, Qi, additional, Gill, Upkar, additional, Chow, Wan Cheng, additional, Bertoletti, Antonio, additional, and Kennedy, Patrick, additional

Published
2024
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12. Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

Author

Renia, Laurent, Goh, Yun Shan, Rouers, Angeline, Le Bert, Nina, Chia, Wan Ni, Chavatte, Jean-Marc, Fong, Siew‐Wai, Chang, Zi Wei, Zhuo, Nicole Ziyi, Tay, Matthew Zirui, Chan, Yi-Hao, Tan, Chee Wah, Yeo, Nicholas Kim‐Wah, Amrun, Siti Naqiah, Huang, Yuling, Wong, Joel Xu En, Hor, Pei Xiang, Loh, Chiew Yee, Wang, Bei, Ngoh, Eve Zi Xian, Salleh, Siti Nazihah Mohd, Carissimo, Guillaume, Dowla, Samanzer, Lim, Alicia Jieling, Zhang, Jinyan, Lim, Joey Ming Er, Wang, Cheng-I., Ding, Ying, Pada, Surinder, Sun, Louisa Jin, Somani, Jyoti, Lee, Eng Sing, Ong, Desmond Luan Seng, Leo, Yee‐Sin, MacAry, Paul A., Lin, Raymond Tzer Pin, Wang, Lin-Fa, Ren, Ee Chee, Lye, David C., Bertoletti, Antonio, Young, Barnaby Edward, and Ng, Lisa F. P.

Published
2022
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15. Prevalence and functional profile of SARS-CoV-2 T cells in asymptomatic Kenyan adults

Author

Samandari, Taraz, Ongalo, Joshua B., McCarthy, Kimberly D., Biegon, Richard K., Madiega, Philister A., Mithika, Anne, Orinda, Joseph, Mboya, Grace M., Mwaura, Patrick, Anzala, Omu, Onyango, Clayton, Oluoch, Fredrick O., Osoro, Eric, Dutertre, Charles-Antoine, Tan, Nicole, Hang, Shou Kit, Hariharaputran, Smrithi, Lye, David C., Herman-Roloff, Amy, Le Ber, Nina, and Bertoletti, Antonio

Subjects
T cells -- Physiological aspects -- Health aspects, Immune response -- Physiological aspects -- Health aspects, Immunity -- Health aspects, Health care industry
Abstract

BACKGROUND. SARS-CoV-2 infection in Africa has been characterized by a less severe disease profile than what has been observed elsewhere, but the profile of SARS-CoV-2-specific adaptive immunity in these mainly asymptomatic patients has not, to our knowledge, been analyzed. METHODS. We collected blood samples from residents of rural Kenya (n = 80), who had not experienced any respiratory symptoms or had contact with individuals with COVID-19 and had not received COVID-19 vaccines. We analyzed spike- specific antibodies and T cells specific for SARS-CoV-2 structural (membrane, nucleocapsid, and spike) and accessory (ORF3a, ORF7, ORF8) proteins. Pre-pandemic blood samples collected in Nairobi (n = 13) and blood samples from mild-to-moderately symptomatic COVID-19 convalescent patients (n = 36) living in the urban environment of Singapore were also studied. RESULTS. Among asymptomatic Africans, we detected anti-spike antibodies in 41.0% of the samples and T cell responses against 2 or more SARS-CoV-2 proteins in 82.5% of samples examined. Such a pattern was absent in the pre-pandemic samples. Furthermore, distinct from cellular immunity in European and Asian COVID-19 convalescents, we observed strong T cell immunogenicity against viral accessory proteins (ORF3a, ORF8) but not structural proteins, as well as a higher IL-10/ IFN-[gamma] cytokine ratio profile. CONCLUSIONS. The high incidence of T cell responses against different SARS-CoV-2 proteins in seronegative participants suggests that serosurveys underestimate SARS-CoV-2 prevalence in settings where asymptomatic infections prevail. The functional and antigen-specific profile of SARS-CoV-2-specific T cells in African individuals suggests that environmental factors can play a role in the development of protective antiviral immunity. FUNDING. US Centers for Disease Control and Prevention, Division of Global Health Protection; the Singapore Ministry of Health's National Medical Research Council (COVID19RF3-0060, COVID19RF-001, COVID19RF-008, MOH-StaR17Nov-0001)., Introduction SARS-CoV-2 infection in Africa is characterized by a low number of mild and severe cases of disease (1, 2). The incidence of severe COVID-19 has been particularly low in [...]

Published
2023
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16. Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2

Author

Swadling, Leo, Diniz, Mariana O., Schmidt, Nathalie M., Amin, Oliver E., Chandran, Aneesh, Shaw, Emily, Pade, Corinna, Gibbons, Joseph M., Le Bert, Nina, Tan, Anthony T., Jeffery-Smith, Anna, Tan, Cedric C. S., Tham, Christine Y. L., Kucykowicz, Stephanie, Aidoo-Micah, Gloryanne, Rosenheim, Joshua, Davies, Jessica, Johnson, Marina, Jensen, Melanie P., Joy, George, McCoy, Laura E., Valdes, Ana M., Chain, Benjamin M., Goldblatt, David, Altmann, Daniel M., Boyton, Rosemary J., Manisty, Charlotte, Treibel, Thomas A., Moon, James C., van Dorp, Lucy, Balloux, Francois, McKnight, Áine, Noursadeghi, Mahdad, Bertoletti, Antonio, and Maini, Mala K.

Published
2022
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17. Immunotherapy of HBV-related advanced hepatocellular carcinoma with short-term HBV-specific TCR expressed T cells: results of dose escalation, phase I trial

Author

Meng, Fanping, Zhao, Jinfang, Tan, Anthony Tanoto, Hu, Wei, Wang, Si-Yu, Jin, Jiehua, Wu, Juan, Li, Yuanyuan, Shi, Lei, Fu, Jun-Liang, Yu, Shuangjie, Shen, Yingjuan, Liu, Limin, Luan, Junqing, Shi, Ming, Xie, Yunbo, Zhou, Chun-Bao, Wong, Regina Wanju, Lu-En, Wai, Koh, Sarene, Bertoletti, Antonio, Wang, Tingting, Zhang, Ji-Yuan, and Wang, Fu-Sheng

Published
2021
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18. Therapeutic vaccine BRII-179 restores HBV-specific immune responses in patients with chronic HBV in a phase Ib/IIa study

Author

Ma, Haiyan, Lim, Tien Huey, Leerapun, Apinya, Weltman, Martin, Jia, Jidong, Lim, Young-suk, Tangkijvanich, Pisit, Sukeepaisarnjaroen, Wattana, Ji, Yun, Le Bert, Nina, Li, Dong, Zhang, Yao, Hamatake, Robert, Tan, Nicole, Li, Chunming, Strasser, Simone I., Ding, Huiguo, Yoon, Jung-Hwan, Stace, Nigel H., Ahmed, Tanvir, Anderson, Dave E., Yan, Li, Bertoletti, Antonio, Zhu, Qing, and Yuen, Man-Fung

Published
2021
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20. Hepatitis B Virus

Author

Bertoletti, Antonio, Huang, Hongming, Gershwin, M. Eric, editor, M. Vierling, John, editor, Tanaka, Atsushi, editor, and P. Manns, Michael, editor

Published
2020
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24. T‐cell immunity against Severe Acute Respiratory Syndrome Coronavirus 2 proteins in patients with type 1 diabetes.

Author

Palmieri, Camillo, Santamaria, Gianluca, Cristiani, Costanza Maria, Garofalo, Cinzia, Tham, Christine Y. L., Abatino, Antonio, Cutruzzolà, Antonio, Parise, Martina, Aversa, Ilenia, Malanga, Donatella, Gallo, Raffaella, Cuda, Giovanni, Viglietto, Giuseppe, Costanzo, Francesco, Bertoletti, Antonio, Gnasso, Agostino, and Irace, Concetta

Subjects
SARS-CoV-2, COVID-19, TYPE 1 diabetes, MONONUCLEAR leukocytes, T cell receptors
Abstract

Aims: Individuals with type 1 diabetes (T1D) do not appear to have an elevated risk of severe Coronavirus Disease 19 (COVID‐19). Pre‐existing immune reactivity to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) in unexposed individuals may serve as a protective factor. Hence, our study was designed to evaluate the existence of T cells with reactivity against SARS‐CoV‐2 antigens in unexposed patients with T1D. Materials and methods: Peripheral blood mononuclear cells (PBMCs) were collected from SARS‐CoV‐2 unexposed patients with T1D and healthy control subjects. SARS‐CoV‐2 specific T cells were identified in PBMCs by ex‐vivo interferon (IFN)γ‐ELISpot and flow cytometric assays. The epitope specificity of T cells in T1D was inferred through T Cell Receptor sequencing and GLIPH2 clustering analysis. Results: T1D patients unexposed to SARS‐CoV‐2 exhibited higher rates of virus‐specific T cells than controls. The T cells primarily responded to peptides from the ORF7/8, ORF3a, and nucleocapsid proteins. Nucleocapsid peptides predominantly indicated a CD4+ response, whereas ORF3a and ORF7/8 peptides elicited both CD4+ and CD8+ responses. The GLIPH2 clustering analysis of TCRβ sequences suggested that TCRβ clusters, associated with the autoantigens proinsulin and Zinc transporter 8 (ZnT‐8), might share specificity towards ORF7b and ORF3a viral epitopes. Notably, PBMCs from three T1D patients exhibited T cell reactivity against both ORF7b/ORF3a viral epitopes and proinsulin/ZnT‐8 autoantigens. Conclusions: The increased frequency of SAR‐CoV‐2‐ reactive T cells in T1D patients might protect against severe COVID‐19 and overt infections. These results emphasise the long‐standing association between viral infections and T1D. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Liver fibrosis and CD206+ macrophage accumulation are suppressed by anti-GM-CSF therapy

Author

Tan-Garcia, Alfonso, Lai, Fritz, Yeong, Joe Poh Sheng, Irac, Sergio E., Ng, Pei Y., Msallam, Rasha, Lim, Jeffrey Chun Tatt, Wai, Lu-En, Tham, Christine Y.L., Choo, Su P., Lim, Tony, Young, Dan Y., D'Ambrosio, Roberta, Degasperi, Elisabetta, Perbellini, Riccardo, Newell, Evan, Le Bert, Nina, Ginhoux, Florent, Bertoletti, Antonio, Chen, Qingfeng, and Dutertre, Charles-Antoine

Published
2020
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29. Human liver-resident CD56bright/CD16neg NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways

Author

Hudspeth, Kelly, Donadon, Matteo, Cimino, Matteo, Pontarini, Elena, Tentorio, Paolo, Preti, Max, Hong, Michelle, Bertoletti, Antonio, Bicciato, Silvio, Invernizzi, Pietro, Lugli, Enrico, Torzilli, Guido, Gershwin, M Eric, and Mavilio, Domenico

Subjects
Liver Disease, Digestive Diseases, Aetiology, Underpinning research, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Adult, Antigens, CD, Antigens, Differentiation, T-Lymphocyte, CD56 Antigen, Cell Movement, Endothelial Cells, Humans, Killer Cells, Natural, Kupffer Cells, Lectins, C-Type, Liver, Receptors, CCR5, Receptors, CXCR6, Receptors, Chemokine, Receptors, IgG, Receptors, Virus, Signal Transduction, T-Lymphocytes, Liver immunology, Homing of hepatic NK cells, Cherokees Chemokine receptors, Immunology
Abstract

RationaleThe liver-specific natural killer (NK) cell population is critical for local innate immune responses, but the mechanisms that lead to their selective homing and the definition of their functionally relevance remain enigmatic.ObjectivesWe took advantage of the availability of healthy human liver to rigorously define the mechanisms regulating the homing of NK cells to liver and the repertoire of receptors that distinguish liver-resident NK (lr-NK) cells from circulating counterparts.FindingsNearly 50% of the entire liver NK cell population is composed of functionally relevant CD56(bright) lr-NK cells that localize within hepatic sinusoids. CD56(bright) lr-NK cells express CD69, CCR5 and CXCR6 and this unique repertoire of chemokine receptors is functionally critical as it determines selective migration in response to the chemotactic stimuli exerted by CCL3, CCL5 and CXCL16. Here, we also show that hepatic sinusoids express CCL3(pos) Kupffer cells, CXCL16(pos) endothelial cells and CCL5(pos) T and NK lymphocytes. The selective presence of these chemokines in sinusoidal spaces creates a unique tissue niche for lr-CD56(bright) NK cells that constitutively express CCR5 and CXCR6. CD56(bright) lr-NK cells co-exist with CD56(dim) conventional NK (c-NK) cells that are, interestingly, transcriptionally and phenotypically similar to their peripheral circulating counterparts. Indeed, CD56(dim) c-NK cells lack expression of CD69, CCR5, and CXCR6 but express selectins, integrins and CX3CR1.ConclusionOur findings disclosing the phenotypic and functional differences between lr-Nk cells and c-NK cells are critical to distinguish liver-specific innate immune responses. Hence, any therapeutic attempts at modifying the large population of CD56(bright) lr-NK cells will require modification of hepatic CCR5 and CXCR6.

Published
2016

33. Update of the statements on biology and clinical impact of occult hepatitis B virus infection

Author

Allain, Jean-Pierre, Berg, Thomas, Bertoletti, Antonio, Brunetto, Maurizia Rossana, Bruno, Raffaele, Chen, Ding-Shinn, Coppola, Nicola, Cornberg, Markus, Craxì, Antonio, Dandri, Maura, Di Marco, Vito, Ferrari, Carlo, Gaeta, Giovanni Battista, Glebe, Dieter, Guidotti, Luca G., Kramvis, Anna, Lampertico, Pietro, Li, Chengyao, Liang, Jake, Marzano, Alfredo, Michalak, Thomas I., Pawlotsky, Jean-Michel, Prati, Daniele, Puoti, Massimo, Samuel, Didier, Soriano, Vincent, Squadrito, Giovanni, Sureau, Camille, Trepo, Christian, Yuen, Man-Fung, Raimondo, Giovanni, Locarnini, Stephen, Pollicino, Teresa, Levrero, Massimo, Zoulim, Fabien, and Lok, Anna S.

Published
2019
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34. Use of Expression Profiles of HBV-DNA Integrated Into Genomes of Hepatocellular Carcinoma Cells to Select T Cells for Immunotherapy

Author

Tan, Anthony Tanoto, Yang, Ninghan, Lee Krishnamoorthy, Thinesh, Oei, Vincent, Chua, Alicia, Zhao, Xinyuan, Tan, Hui Si, Chia, Adeline, Le Bert, Nina, Low, Diana, Tan, Hiang Keat, Kumar, Rajneesh, Irani, Farah Gillan, Ho, Zi Zong, Zhang, Qi, Guccione, Ernesto, Wai, Lu-En, Koh, Sarene, Hwang, William, Chow, Wan Cheng, and Bertoletti, Antonio

Published
2019
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35. Favorable vaccine-induced SARS-CoV-2-specific T cell response profile in patients undergoing immune-modifying therapies

Author

Qui, Martin, Chan, Nina Le BerWebber Pak Wo, Tan, Malcolm, Hang, Shou Kit, Hariharaputran, Smrithi, Sim, Jean Xiang Ying, Low, Jenny Guek Hong, Ng, Weiling, Wan, Wei Yee, Ang, Tiing Leong, Bertoletti, Antonio, and Salazar, Ennaliza

Subjects
Immunological research, T cells -- Health aspects -- Physiological aspects, Inflammatory bowel diseases -- Drug therapy -- Patient outcomes, Immune response -- Research, Antirheumatic agents -- Patient outcomes, Biological response modifiers -- Patient outcomes, Health care industry
Abstract

BACKGROUND. Patients undergoing immune-modifying therapies demonstrate a reduced humoral response after COVID-19 vaccination, but we lack a proper evaluation of the effect of such therapies on vaccine-induced T cell responses. METHODS. We longitudinally characterized humoral and spike-specific T cell responses in patients with inflammatory bowel disease (IBD), who were on antimetabolite therapy (azathioprine or methotrexate), TNF inhibitors, and/or other biologic treatment (anti-integrin or anti-p40) for up to 6 months after completing 2-dose COVID-19 mRNA vaccination. RESULTS. We demonstrate that a spike-specific T cell response was not only induced in treated patients with IBD at levels similar to those of healthy individuals, but also sustained at higher magnitude for up to 6 months after vaccination, particularly in those treated with TNF inhibitor therapy. Furthermore, the spike-specific T cell response in these patients was mainly preserved against mutations present in SARS-CoV-2 B.1.1.529 (Omicron) and characterized by a Th1/IL-10 cytokine profile. CONCLUSION. Despite the humoral response defects, patients under immune-modifying therapies demonstrated a favorable profile of vaccine-induced T cell responses that might still provide a layer of COVID-19 protection. FUNDING. This study was funded by the National Centre for Infectious Diseases (NCID) Catalyst Grant (FY2021ES) and the National Research Fund Competitive Research Programme (NRF-CRP25-2020-0003)., Introduction Immune-modifying agents are the treatment of choice for different chronic inflammatory diseases of autoimmune origin. Antimetabolites (azathioprine and methotrexate) or biologics, such as TNF inhibitors (adalimumab and infliximab), anti-p40 [...]

Published
2022
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36. Activated macrophages promote hepatitis C virus entry in a tumor necrosis factor‐dependent manner

Author

Fletcher, Nicola F, Sutaria, Rupesh, Jo, Juandy, Barnes, Amy, Blahova, Miroslava, Meredith, Luke W, Cosset, Francois‐Loic, Curbishley, Stuart M, Adams, David H, Bertoletti, Antonio, and McKeating, Jane A

Subjects
Digestive Diseases, Hepatitis - C, Liver Disease, Chronic Liver Disease and Cirrhosis, Emerging Infectious Diseases, Infectious Diseases, Hepatitis, Aetiology, 2.1 Biological and endogenous factors, Infection, Good Health and Well Being, Carcinoma, Hepatocellular, Cell Line, Tumor, Cell Polarity, Hep G2 Cells, Hepacivirus, Hepatitis C, Humans, Immunity, Innate, Interleukin-1beta, Liver Neoplasms, Macrophage Activation, Macrophages, Occludin, Tetraspanin 28, Tight Junctions, Tumor Necrosis Factor-alpha, Virus Internalization, Medical Biochemistry and Metabolomics, Clinical Sciences, Immunology, Gastroenterology & Hepatology
Abstract

UnlabelledMacrophages are critical components of the innate immune response in the liver. Chronic hepatitis C is associated with immune infiltration and the infected liver shows a significant increase in total macrophage numbers; however, their role in the viral life cycle is poorly understood. Activation of blood-derived and intrahepatic macrophages with a panel of Toll-like receptor agonists induce soluble mediators that promote hepatitis C virus (HCV) entry into polarized hepatoma cells. We identified tumor necrosis factor α (TNF-α) as the major cytokine involved in this process. Importantly, this effect was not limited to HCV; TNF-α increased the permissivity of hepatoma cells to infection by Lassa, measles and vesicular stomatitis pseudoviruses. TNF-α induced a relocalization of tight junction protein occludin and increased the lateral diffusion speed of HCV receptor tetraspanin CD81 in polarized HepG2 cells, providing a mechanism for their increased permissivity to support HCV entry. High concentrations of HCV particles could stimulate macrophages to express TNF-α, providing a direct mechanism for the virus to promote infection.ConclusionThis study shows a new role for TNF-α to increase virus entry and highlights the potential for HCV to exploit existing innate immune responses in the liver to promote de novo infection events.

Published
2014

39. Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming

Author

Bénéchet, Alexandre P., De Simone, Giorgia, Di Lucia, Pietro, Cilenti, Francesco, Barbiera, Giulia, Le Bert, Nina, Fumagalli, Valeria, Lusito, Eleonora, Moalli, Federica, Bianchessi, Valentina, Andreata, Francesco, Zordan, Paola, Bono, Elisa, Giustini, Leonardo, Bonilla, Weldy V., Bleriot, Camille, Kunasegaran, Kamini, Gonzalez-Aseguinolaza, Gloria, Pinschewer, Daniel D., Kennedy, Patrick T. F., Naldini, Luigi, Kuka, Mirela, Ginhoux, Florent, Cantore, Alessio, Bertoletti, Antonio, Ostuni, Renato, Guidotti, Luca G., and Iannacone, Matteo

Published
2019
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43. BNT162b2 vaccine induced variant-specific immunity, safety and risk of Omicron breakthrough infection in children aged 5 to 11 years: A cohort study

Author

Yung, Chee Fu, primary, Bert, Nina Le, additional, Kam, Kai Qian, additional, Saffari, Seyed Ehsan, additional, Tan, Chee Wah, additional, Mah, Yun Yan, additional, Zhang, Jinyan, additional, Yeoh, Aileen Ying-Yan, additional, Zhu, Feng, additional, Hariharaputran, Smrithi, additional, Chong, Chia Yin, additional, Bertoletti, Antonio, additional, and Wang, Linfa, additional

Published
2023
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45. Rapid functional secretome analysis of HBV-specific T cells to guide clinical management of CHB patients

Author

Le Bert, Nina, primary, Koffas, Apostolos, additional, Tan, Anthony, additional, Mak, Lung-Yi, additional, Stretch, Sophie, additional, Hang, Shou Kit, additional, Ma, Haiyan, additional, Lee, Ariel, additional, Ji, Yun, additional, Gill, Upkar, additional, Chen, Qi, additional, Zhu, Qing, additional, Bertoletti, Antonio, additional, and Kennedy, Patrick, additional

Published
2023
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48. Intrahepatic CD206+ macrophages contribute to inflammation in advanced viral-related liver disease

Author

Tan-Garcia, Alfonso, Wai, Lu-En, Zheng, Dahai, Ceccarello, Erica, Jo, Juandy, Banu, Nasirah, Khakpoor, Atefeh, Chia, Adeline, Tham, Christine Y.L., Tan, Anthony T., Hong, Michelle, Keng, Choong Tat, Rivino, Laura, Tan, Kai Chah, Lee, Kang Hoe, Lim, Seng Gee, Newell, Evan W., Pavelka, Norman, Chen, Jinmiao, Ginhoux, Florent, Chen, Qingfeng, Bertoletti, Antonio, and Dutertre, Charles-Antoine

Published
2017
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