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1. An Argentinean cohort of patients with rheumatic and immune-mediated diseases vaccinated for SARS-CoV-2: the SAR-CoVAC Registry—protocol and preliminary data

Author

Isnardi, Carolina A., Schneeberger, Emilce E., Kreimer, Jennifer L., Luna, Paula C., Echeverría, Cristina, Roberts, Karen, de la Vega, María Celina, Virasoro, Belen María, Landi, Margarita, Quintana, Rosana, Exeni, Maria Eugenia D’Angelo, Kogan, Nora, Petkovic, Ingrid, Pereira, Dora, De Los Ángeles Correa, Maria, Zelaya, Marcos David, Tissera, Yohana, Elkin, María Soledad Gálvez, Pisoni, Cecilia Nora, Alonso, Carla, Cogo, Adriana Karina, Cosatti, Micaela Ana, García, Lucila, Retamozo, Cinthya, de los Ángeles Severina, María, Nieto, Romina Estefania, Rosemffet, Marcos, Mussano, Eduardo, Bertoli, Ana, Savio, Verónica G., Cosentino, Vanesa, and Pons-Estel, Guillermo J.

Published
2022
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2. Environmental and societal factors associated with COVID-19-related death in people with rheumatic disease: an observational study

Author

Dahou, Brahim, Gómez, Gimena, Roberts, Karen, Baez, Roberto M, Castro Coello, Vanessa V, Haye Salinas, María J, Maldonado, Federico N, Reyes, Alvaro A, Alle, Gelsomina, Tanten, Romina, Maldonado Ficco, Hernán, Nieto, Romina, Gobbi, Carla, Tissera, Yohana, Pisoni, Cecilia, Paula, Alba, Albiero, Juan A, Schmid, Maria M, Cosatti, Micaela, Gamba, Maria J, Leandro, Carlevaris, Cusa, María A, German, Noelia, Bellomio, Veronica, Takashima, Lorena, Pera, Mariana, Cogo, Karina, Gálvez Elkin, Maria S, Medina, María A, Savio, Veronica, Rojas Tessel, Romina, Alamino, Rodolfo P, Werner, Marina L, Ornella, Sofía, Casalla, Luciana, de la Vega, Maria, Severina, María, García, Mercedes, Gonzalez Lucero, Luciana, Romeo, Cecilia, Moyano, Sebastián, Barbich, Tatiana, Bertoli, Ana, Baños, Andrea, Petruzzelli, Sandra, Matellan, Carla, Conti, Silvana, Lazaro, Maria A, Rodriguez Gil, Gustavo F, Risueño, Fabian, Quaglia, Maria I, Scafati, Julia, Cuchiaro, Natalia L, Rebak, Jonathan E, Pineda, Susana I, Calvo, María E, Picco, Eugenia, Yanzi, Josefina G, Maid, Pablo, Guaglianone, Debora, Morbiducci, Julieta S, Porta, Sabrina, Herscovich, Natalia, Velasco Zamora, José L, Kisluk, Boris, Castaños Menescardi, Maria S, Gallo, Rosana, Martire, María V, Maldini, Carla, Goizueta, Cecilia, de la Vega Fernandez, Sabrina S, Aeschlimann, Carolina, Subils, Gisela, Rath, Eva, Piette, Yves, Devinck, Mieke, Maeyaert, Bea, Machado Ribeiro, Francinne, Euzebio Ribeiro, Sandra L, Pinheiro, Marcelo, Ibáñez, Sebastián, Chassin Trubert, Anne-Marie, Dong, Lingli, Cajas, Lui, Barešić, Marko, Anić, Branimir, Ćulo, Melanie-Ivana, Pavelić, Tea A, Stranski, Kristina K, Karanovic, Boris, Vencovsky, Jiri, Píchová, Marta, Filkova, Maria, Hamoud, Hesham, Vassilopoulos, Dimitrios, Guzman Melgar, Gabriela M, So, Ho, Király, Márta, Vojdanian, Mahdi, Balbir Gurman, Alexandra, Abutiban, Fatemah, Zepa, Julija, Bulina, Inita, Bukauskiene, Loreta, Zazueta Montiel, Beatriz E, Castillo Ortiz, Angel A, Zamora Tehozol, Erick, Vega Morales, David, Cervántes Rosete, Diana, Martín Nares, Eduardo, Rodriguez Reyna, Tatiana S, Rull Gabayet, Marina, Alpízar Rodríguez, Deshiré, Irazoque, Fedra, Jimenez, Xochitl, Geurts van Bon, Lenny, Zijlstra, Theo, Hoekstra, Monique, Al Adhoubi, Nasra, Salim, Babur, Giraldo, Enrique, Salinas, Ariel, Ugarte Gil, Manuel, Nowakowski, Jarosław, Conway, Richard, Flood, Rachael, McCarthy, Geraldine, Felea, Ioana, Filipescu, Ileana, Rednic, Simona, Groseanu, Laura, Tamas, Maria M, Mlynarikova, Vanda, Skamlova, Martina, Zlnay, Martin, Mičeková, Dagmar, Capova, Lubica, Macejova, Zelmira, Šteňová, Emőke, Raffayova, Helena, Belakova, Gabriela, Strakova, Eva, Senčarová, Marieta, Žlnayová, Soňa, Sabová, Anna, Spisakova, Daniela, Oetterová, Mária, Lukacova, Olga, Bakosova, Martina, Hocevar, Alojzija, de la Torre Rubio, Natalia, Alegre Sancho, Juan J, Corteguera Coro, Montserrat, Cobeta Garcia, Juan C, Torres Martin, Maria C, Campos, Jose, Gomez Puerta, Jose A, Yardimci, Gozd K, Akar, Servet, Icacan, Ozan C, ÇELİK, Selda, Vasylets, Viktoriia, Yeoh, Su-Ann, Vandevelde, Claire, Dunt, Sasha, Leeder, Jane, Macphie, Elizabeth, Salerno, Rosaria, Graver, Christine, Williams, Katie, O'Reilly, Sheila, Devine, Kirsty, Tyler, Jennifer, Warner, Elizabeth, Pilcher, James, Patel, Samir, Nikiphorou, Elena, Chadwick, Laura, Jones, Caroline M, Harrison, Beverley, Thornton, Lucy, O'Kane, Diana, Fusi, Lucia, Low, Audrey, Horton, Sarah, Jatwani, Shraddha, Baig, Sara, Bajwa, Hammad, Berglund, Vernon, Dahle, Angela, Dorman, Walter, Hargrove, Jody, Hilton, Maren, Lebedoff, Nicholas, Leonard, Susan, Morgan, Jennifer, Pfeifer, Emily, Skemp, Archibald, Wilson, Jeffrey, Wolff, Anne, Cepeda, Eduardo, Todd, Derrick, Hare, Denise, Calabrese, Cassandra, Adams, Christopher, Khosroshahi, Arezou, Kilian, Adam, White, Douglas, Winter, Melanie, Fields, Theodore, Siegel, Caroline, Daver, Nicole, Harvey, Melissa, Kramer, Neil, Lamore, Concetta, Hogarty, Suneya, Yeter, Karen, Siddique, Faizah, Ban, Byung, Tanner, Tamar, Ruderman, Eric, Davis, William, Quinet, Robert, Scopelitis, Evangeline, Toribio, Karen, Webb Detiege, Tameka, Zakem, Jerald, Abbass, Khurram, Kepecs, Gilbert, Miranda, Lilliam, Guma, Michael, Haikal, Ammar, Mody, Sushama, Mueller, Daric, Jayatilleke, Arundathi, Zell, JoAnn, Bays, Alison, Dao, Kathryn, Ezzati, Fatemeh, Parks, Deborah, Karp, David, Quiceno, Guillermo, Izadi, Zara, Gianfrancesco, Milena A, Schmajuk, Gabriela, Jacobsohn, Lindsay, Katz, Patricia, Rush, Stephanie, Ja, Clairissa, Taylor, Tiffany, Shidara, Kie, Danila, Maria I, Wysham, Katherine D, Strangfeld, Anja, Mateus, Elsa F, Hyrich, Kimme L, Gossec, Laure, Carmona, Loreto, Lawson-Tovey, Saskia, Kearsley-Fleet, Lianne, Schaefer, Martin, Al-Emadi, Samar, Sparks, Jeffrey A, Hsu, Tiffany Y-T, Patel, Naomi J, Wise, Leanna, Gilbert, Emily, Duarte-García, Alí, Valenzuela-Almada, Maria O, Ugarte-Gil, Manuel F, Ljung, Lotta, Scirè, Carlo A, Carrara, Greta, Hachulla, Eric, Richez, Christophe, Cacoub, Patrice, Thomas, Thierry, Santos, Maria J, Bernardes, Miguel, Hasseli, Rebecca, Regierer, Anne, Schulze-Koops, Hendrik, Müller-Ladner, Ulf, Pons-Estel, Guillermo, Nieto, Romina E, Pisoni, Cecilia N, Tissera, Yohana S, Xavier, Ricardo, Lopes Marques, Claudia D, Pileggi, Gecilmara C S, Robinson, Philip C, Machado, Pedro M, Sirotich, Emily, Liew, Jean W, Hausmann, Jonathan S, Sufka, Paul, Grainger, Rebecca, Bhana, Suleman, Gore-Massy, Monique, Wallace, Zachary S, and Yazdany, Jinoos

Published
2022
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3. Outcomes of COVID-19 in patients with primary systemic vasculitis or polymyalgia rheumatica from the COVID-19 Global Rheumatology Alliance physician registry: a retrospective cohort study

Author

Dahou, Brahim, Rath, Eva, Piette, Yves, Devinck, Mieke, Maeyaert, Bea, Machado Ribeiro, Francinne, Euzebio Ribeiro, Sandra Lucia, Pinheiro, Marcelo, Quintana, Rosana, Gómez, Gimena, Roberts, Karen, Baez, Roberto Miguel, Castro Coello, Vanessa, Haye Salinas, María J., Maldonado, Federico Nicolas, Reyes Torres, Alvaro Andres, Alle, Gelsomina, Tanten, Romina, Maldonado Ficco, Hernán, Nieto, Romina, Gobbi, Carla, Tissera, Yohana, Pisoni, Cecilia, Paula, Alba, Albiero, Juan Alejandro, Schmid, Maria Marcela, Cosatti, Micaela, Gamba, Maria Julieta, Leandro, Carlevaris, Cusa, María Alejandra, German, Noelia, Bellomio, Veronica, Takashima, Lorena, Pera, Mariana, Cogo, Karina, Gálvez Elkin, Maria Soledad, Medina, María Alejandra, Savio, Veronica, Rojas Tessel, Ivana Romina, Perez Alamino, Rodolfo, Werner, Marina Laura, Ornella, Sofía, Casalla, Luciana, de la Vega, Maria, Severina, María, García, Mercedes, Gonzalez Lucero, Luciana, Romeo, Cecilia, Moyano, Sebastián, Barbich, Tatiana, Bertoli, Ana, Baños, Andrea, Petruzzelli, Sandra, Matellan, Carla, Conti, Silvana, Lazaro, Ma. Alicia, Rodriguez Gil, Gustavo Fabián, Risueño, Fabian, Quaglia, Maria Isabel, Scafati, Julia, Cuchiaro, Natalia Lili, Rebak, Jonathan Eliseo, Pineda, Susana Isabel, Calvo, María Elena, Picco, Eugenia, Gallino Yanzi, Josefina, Maid, Pablo, Guaglianone, Debora, Morbiducci, Julieta Silvana, Porta, Sabrina, Herscovich, Natalia, Velasco Zamora, José Luis, Kisluk, Boris, Castaños Menescardi, Maria Sol, Gallo, Rosana, Martire, María Victoria, Maldini, Carla, Goizueta, Cecilia, de la Vega Fernandez, Sabrina Solange, Aeschlimann, Carolina, Subils, Gisela, Ibáñez, Sebastián, Chassin-Trubert, Anne-Marie, Dong, Lingli, Cajas, Lui, Barešic, Marko, Anic, Branimir, Culo, Melanie-Ivana, Pavelic, Tea Ahel, Kovacevic Stranski, Kristina, Karanovic, Boris, Vencovsky, Jiri, Píchová, Marta, Filkova, Maria, Hamoud, Hesham, Vassilopoulos, Dimitrios, Guzman Melgar, Gabriela Maria, So, Ho, Király, Márta, Vojdanian, Mahdi, Balbir-Gurman, Alexandra, Abutiban, Fatemah, Zepa, Julija, Bulina, Inita, Bukauskiene, Loreta, Zaueta, Beatriz, Castillo Ortiz, Angel Alejandro, Zamora Tehozol, Erick, Vega, David, Cervántes Rosete, Diana, Martín Nares, Eduardo, Rodriguez-Reyna, Tatiana Sofia, Rull Gabayet, Marina, Alpízar-Rodríguez, Deshiré, Irazoque, Fedra, Jimenez, Xochitl, Geurts-van Bon, Lenny, Zijlstra, Theo, Hoekstra, Monique, Al-Adhoubi, Nasra, Salim, Babur, Giraldo, Enrique, Salinas, Ariel, Ugarte-Gil, Manuel, Nowakowski, Jaroslaw, Al-Emadi, Samar, Conway, Richard, Flood, Rachael, McCarthy, Geraldine, Felea, Ioana, Filipescu, Ileana, Rednic, Simona, Groseanu, Laura, Tamas, Maria Magdelena, Mlynarikova, Vanda, Skamlova, Martina, Zlnay, Martin, Miceková, Dagmar, Capova, Lubica, Macejova, Zelmira, Štenová, Emoke, Raffayova, Helena, Belakova, Gabriela, Strakova, Eva, Sencarová, Marieta, Žlnayová, Sona, Anna Sabová, Anna, Spisakova, Daniela, Oetterová, Mária, Lukacova, Olga, Bakosova, Martina, Hocevar, Alojzija, de la Torre-Rubio, Natalia, Alegre Sancho, Juan José, Corteguera Coro, Montserrat, Cobeta Garcia, Juan Carlos, Torres Martin, Maria Carmen, Campos, Jose, Gomez Puerta, Jose A, Yardimci, Gozd Kubra, Akar, Servet, Icacan, Ozan Cemal, Çelik, Selda, Vasylets, Viktoriia, Yeoh, Su-Ann, Vandevelde, Claire, Dunt, Sasha, Leeder, Jane, Macphie, Elizabeth, Salerno, Rosaria, Graver, Christine, Williams, Katie, O'Reilly, Sheila, Devine, Kirsty, Tyler, Jennifer, Warner, Elizabeth, Pilcher, James, Patel, Samir, Nikiphorou, Elena, Chadwick, Laura, Jones, Caroline Mulvaney, Harrison, Beverley, Thornton, Lucy, O'Kane, Diana, Fusi, Lucia, Low, Audrey, Horton, Sarah, Jatwani, Shraddha, Baig, Sara, Bajwa, Hammad, Berglund, Vernon, Dahle, Angela, Dorman, Walter, Hargrove, Jody, Hilton, Maren, Lebedoff, Nicholas, Leonard, Susan, Morgan, Jennifer, Pfeifer, Emily, Skemp, Archibald, Wilson, Jeffrey, Wolff, Anne, Cepeda, Eduardo, D'Silva, Kristin, Hsu, Tiffany, Patel, Naomi, Sparks, Jeffrey, Todd, Derrick, Wallace, Zachary, Hare, Denise, Calabrese, Cassandra, Adams, Christopher, Khosroshahi, Arezou, Kilian, Adam, White, Douglas, Winter, Melanie, Fields, Theodore, Siegel, Caroline, Daver, Nicole, Harvey, Melissa, Kramer, Neil, Lamore, Concetta, Hogarty, Suneya, Yeter, Karen, Wise, Leanna, Siddique, Faizah, Ban, Byung, Tanner, Tamar, Ruderman, Eric, Davis, William, Quinet, Robert, Scopelitis, Evangeline, Toribio Toribio, Karen, Webb-Detiege, Tameka, Zakem, Jerald, Abbass, Khurram, Kepecs, Gilbert, Miranda, Lilliam, Guma, Michael, Haikal, Ammar, Mody, Sushama, Mueller, Daric, Jayatilleke, Arundathi, Zell, JoAnn, Bays, Alison, Dao, Kathryn, Fatemeh, Ezzati, Parks, Deborah, Karp, David, Quiceno, Guillermo, Sattui, Sebastian E, Putman, Michael S, Seet, Andrea M, Gianfrancesco, Milena A, Beins, Kaley, Hill, Catherine, Liew, David, Mackie, Sarah L, Mehta, Puja, Neill, Lorna, Gomez, Gimena, Salinas, Maria Isabel Haye, Mariz, Henrique Ataide, de Sousa Studart, Samia Araujo, Araujo, Nafice Costa, Knight, Ann, Rozza, Davide, Quartuccio, Luca, Samson, Maxime, Bally, Stéphane, Maria, Alexandre TJ, Chazerain, Pascal, Hasseli, Rebecca, Müller-Ladner, Ulf, Hoyer, Bimba F, Voll, Reinhard, Torres, Rita Pinheiro, Luis, Mariana, Ribeirio, Sandra Lucia Euzebio, Sparks, Jeffrey A, Hsu, Tiffany Y-T, D’Silva, Kristin M, Patel, Naomi J, Gilbert, Emily, Almada, Maria Valenzuela, Duarte-García, Alí, Jacobsohn, Lindsay, Izadi, Zara, Strangfeld, Anja, Mateus, Elsa F, Hyrich, Kimme L, Gossec, Laure, Carmona, Loreto, Lawson-Tovey, Saskia, Kearsley-Fleet, Lianne, Schaefer, Martin, Sirotich, Emily, Hausmann, Jonathan S, Sufka, Paul, Bhana, Suleman, Liew, Jean W, Grainger, Rebecca, Machado, Pedro M, Wallace, Zachary S, Yazdany, Jinoos, and Robinson, Philip C

Published
2021
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5. Reliability of OMERACT ultrasound elementary lesions in gout: results from a multicenter exercise

Author

Cazenave, Tomas, Martire, Victoria, Reginato, Anthony M., Gutierrez, Marwin, Waimann, Christian Alfredo, Pineda, Carlos, Rosa, Javier Eduardo, Ruta, Santiago, Sedano-Santiago, Oscar, Bertoli, Ana Maria, Audisio, Marcelo, Hernandez-Diaz, Cristina, Ventura-Rios, Lucio, Quintero, Maritza, De Miguel, Eugenio, Alvarez-del-Castillo-Araujo, Ana Laura, Abril, Andy, Ayala-Ledesma, Eliana Natalí, Alarcon-Isidro, Edith, Santiago, Maria Lida, Pera, Mariana Alejandra, Urquiola, Cecilia, Rodriguez Gil, Gustavo, Saldarriaga Rivera, Lina Maria, Cefferino, Cesar, Benegas, Mariana, Diaz Cortes, Mario Enrique, Bravo, Maximiliano, Peiteado, Diana, Estrella, Natalia Anahi, Micas, Roser Areny, Saavedra Muñoz, Jorge, Arape Toyo, Rodolfo del Carmen, Gálvez Elkin, Maria Soledad, Spindler, Walter Javier, Sandobal, Clarisa, Marin, Josefina, Lima Gomes Ochtrop, Manuella, Pavao Ayala, Ricardo, Catay, Erika Roxana, Py, Guillermo Enrique, Aguilar, Gabriel Hector, Rengel Colina, Yvonne Yona, Airoldi, Carla Antonela, Mora-Trujillo, Claudia Selene, Kohan, Maria Paula, Urioste Eguez, Lorena Evelin, Castillo-Gallego, Concepción, Diaz-Coto, Jose Francisco, Tate, Patricio, Saucedo, Carla Magali, Vega-Hinojosa, Oscar, Troitiño, Cristian Jonatan, Marengo, Maria Florencia, Marcaida, Priscila Maria, Monjo Henry, Irene, Muñoz-Louis, Roberto, Solano, Carla, Fernandez Castillo, Felix Reinaldo, Graf, Cesar Enrique, Guinsburg, Mara, Santa Cruz, Maria Julia, Navarta Ortiz, David Alejandro, Alva Linares, Magaly, Rosemffet, Marcos Gabriel, and Pan-American League of Associations for Rheumatology (PANLAR) Ultrasound Study Group

Published
2019
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6. Efficacité à court terme des infiltrations locales de corticoïdes réalisées « à l’aveugle » versus « sous contrôle échographique » dans le traitement de la ténosynovite chez les patients atteints d’arthrite inflammatoire chronique : étude comparative randomisée

Author

Aliste, Marta, Alva, Magaly, Aragón-Laínez, R.A., Areny, Roser, Audisio, Marcelo, Bertoli, Ana, Bouffard, José Antonio, Caballero-Uribe, Carlo Vinicio, Camacho, Walter, Díaz-Coto, José Francisco, Filippucci, Emilio, Flores, Víctor, Hoffman, Fritz, Kurslikova, María, Mendonça, José Alexander, Moya, Carlos, Mora, Claudia, Muñoz-Louis, Roberto, Py, Guillermo Enrique, Quintero, Maritza, Rodríguez Henríquez, Pedro, Saavedra, Jorge, Santiago, Lida, Sedano, Oscar, Solano, Carla, Urioste, Lorena, Villota, Orlando, Ceron, Carmen, Saaibi, Diego, Diaz, Mario, Roth, Johannes, Gutierrez, Marwin, Di Matteo, Andrea, Rosemffet, Marcos, Cazenave, Tomas, Rodriguez-Gil, Gustavo, Hernandez Diaz, Cristina, Ventura Rios, Lucio, Zamora, Natalia, del Carmen Gonzalez Guzman, Maria, Carrillo, Ignacio, Okano, Tadashi, Salaffi, Fausto, and Pineda, Carlos

Published
2016
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8. Reactivación de glomerulonefritis lúpica en asociación temporal con vacunas anti SARS-CoV-2

Author

Muñoz, Leila M., Bertoli, Ana María, Rigo, Diego, and Sánchez Freytes, Marcelo

Subjects
R Medicina (General)
Abstract

Debido el alto impacto sanitario que causó el nuevo coronavirus SARS-CoV-2, se procedió al rápido desarrollo e implementación de vacunas en un intento de disminuir su transmisibilidad y las formas graves de la COVID 19. La aprobación de estas vacunas se basó en una adecuada relación riesgo/beneficio, sin embargo, en el año 2021 no disponíamos de sub-estudios en poblaciones especiales; entre ellas, pacientes con lupus eritematoso sistémico (LES). Presentamos dos casos de brote de glomerulonefritis lúpica luego de la inmunización contra SARS-CoV-2 dado por el primer componente de Sputnik V y Sinopharm. Ambas pacientes se encontraban en remisión completa con tratamiento de mantenimiento en dosis estables de micofenolato y libre de glucocorticoides. El brote de glomerulonefritis se presentó con aumento de relación proteinuria/creatininuria y anticuerpos anti ADN positivos sin otros hallazgos acompañantes de relevancia. En ambas pacientes se reinició prednisona (20 y 10 mg/día en caso 1 y 2, respectivamente) y se aumentó la dosis de micofenolato (de 1.5 g/día a 2.0 g/día y de 1.08 a 1.44 g/día de micofenolato sódico en caso 1 y 2, respectivamente) con remisión completa del cuadro. Estos casos son de relevancia ya que introducen una posible asociación entre las diferentes plataformas vacunales anti SARS-CoV-2 y reactivación del LES, a la vez de sugerir la necesidad de un control estrecho en el período post-vacunal en esta población de pacientes., Fil: Muñoz, Leila M. Universidad Católica de Córdoba. Clínica Universitaria Reina Fabiola; Argentina, Fil: Bertoli, Ana María. Universidad Católica de Córdoba. Clínica Universitaria Reina Fabiola; Argentina, Fil: Rigo, Diego. Universidad Católica de Córdoba. Clínica Universitaria Reina Fabiola; Argentina, Fil: Sánchez Freytes, Marcelo. Universidad Católica de Córdoba. Clínica Universitaria Reina Fabiola; Argentina

Published
2022

9. Environmental and societal factors associated with COVID-19-related death in people with rheumatic disease: an observational study

Author

Izadi, Zara, primary, Gianfrancesco, Milena A, additional, Schmajuk, Gabriela, additional, Jacobsohn, Lindsay, additional, Katz, Patricia, additional, Rush, Stephanie, additional, Ja, Clairissa, additional, Taylor, Tiffany, additional, Shidara, Kie, additional, Danila, Maria I, additional, Wysham, Katherine D, additional, Strangfeld, Anja, additional, Mateus, Elsa F, additional, Hyrich, Kimme L, additional, Gossec, Laure, additional, Carmona, Loreto, additional, Lawson-Tovey, Saskia, additional, Kearsley-Fleet, Lianne, additional, Schaefer, Martin, additional, Al-Emadi, Samar, additional, Sparks, Jeffrey A, additional, Hsu, Tiffany Y-T, additional, Patel, Naomi J, additional, Wise, Leanna, additional, Gilbert, Emily, additional, Duarte-García, Alí, additional, Valenzuela-Almada, Maria O, additional, Ugarte-Gil, Manuel F, additional, Ljung, Lotta, additional, Scirè, Carlo A, additional, Carrara, Greta, additional, Hachulla, Eric, additional, Richez, Christophe, additional, Cacoub, Patrice, additional, Thomas, Thierry, additional, Santos, Maria J, additional, Bernardes, Miguel, additional, Hasseli, Rebecca, additional, Regierer, Anne, additional, Schulze-Koops, Hendrik, additional, Müller-Ladner, Ulf, additional, Pons-Estel, Guillermo, additional, Tanten, Romina, additional, Nieto, Romina E, additional, Pisoni, Cecilia N, additional, Tissera, Yohana S, additional, Xavier, Ricardo, additional, Lopes Marques, Claudia D, additional, Pileggi, Gecilmara C S, additional, Robinson, Philip C, additional, Machado, Pedro M, additional, Sirotich, Emily, additional, Liew, Jean W, additional, Hausmann, Jonathan S, additional, Sufka, Paul, additional, Grainger, Rebecca, additional, Bhana, Suleman, additional, Gore-Massy, Monique, additional, Wallace, Zachary S, additional, Yazdany, Jinoos, additional, Dahou, Brahim, additional, Gómez, Gimena, additional, Roberts, Karen, additional, Baez, Roberto M, additional, Castro Coello, Vanessa V, additional, Haye Salinas, María J, additional, Maldonado, Federico N, additional, Reyes, Alvaro A, additional, Alle, Gelsomina, additional, Maldonado Ficco, Hernán, additional, Nieto, Romina, additional, Gobbi, Carla, additional, Tissera, Yohana, additional, Pisoni, Cecilia, additional, Paula, Alba, additional, Albiero, Juan A, additional, Schmid, Maria M, additional, Cosatti, Micaela, additional, Gamba, Maria J, additional, Leandro, Carlevaris, additional, Cusa, María A, additional, German, Noelia, additional, Bellomio, Veronica, additional, Takashima, Lorena, additional, Pera, Mariana, additional, Cogo, Karina, additional, Gálvez Elkin, Maria S, additional, Medina, María A, additional, Savio, Veronica, additional, Rojas Tessel, Romina, additional, Alamino, Rodolfo P, additional, Werner, Marina L, additional, Ornella, Sofía, additional, Casalla, Luciana, additional, de la Vega, Maria, additional, Severina, María, additional, García, Mercedes, additional, Gonzalez Lucero, Luciana, additional, Romeo, Cecilia, additional, Moyano, Sebastián, additional, Barbich, Tatiana, additional, Bertoli, Ana, additional, Baños, Andrea, additional, Petruzzelli, Sandra, additional, Matellan, Carla, additional, Conti, Silvana, additional, Lazaro, Maria A, additional, Rodriguez Gil, Gustavo F, additional, Risueño, Fabian, additional, Quaglia, Maria I, additional, Scafati, Julia, additional, Cuchiaro, Natalia L, additional, Rebak, Jonathan E, additional, Pineda, Susana I, additional, Calvo, María E, additional, Picco, Eugenia, additional, Yanzi, Josefina G, additional, Maid, Pablo, additional, Guaglianone, Debora, additional, Morbiducci, Julieta S, additional, Porta, Sabrina, additional, Herscovich, Natalia, additional, Velasco Zamora, José L, additional, Kisluk, Boris, additional, Castaños Menescardi, Maria S, additional, Gallo, Rosana, additional, Martire, María V, additional, Maldini, Carla, additional, Goizueta, Cecilia, additional, de la Vega Fernandez, Sabrina S, additional, Aeschlimann, Carolina, additional, Subils, Gisela, additional, Rath, Eva, additional, Piette, Yves, additional, Devinck, Mieke, additional, Maeyaert, Bea, additional, Machado Ribeiro, Francinne, additional, Euzebio Ribeiro, Sandra L, additional, Pinheiro, Marcelo, additional, Ibáñez, Sebastián, additional, Chassin Trubert, Anne-Marie, additional, Dong, Lingli, additional, Cajas, Lui, additional, Barešić, Marko, additional, Anić, Branimir, additional, Ćulo, Melanie-Ivana, additional, Pavelić, Tea A, additional, Stranski, Kristina K, additional, Karanovic, Boris, additional, Vencovsky, Jiri, additional, Píchová, Marta, additional, Filkova, Maria, additional, Hamoud, Hesham, additional, Vassilopoulos, Dimitrios, additional, Guzman Melgar, Gabriela M, additional, So, Ho, additional, Király, Márta, additional, Vojdanian, Mahdi, additional, Balbir Gurman, Alexandra, additional, Abutiban, Fatemah, additional, Zepa, Julija, additional, Bulina, Inita, additional, Bukauskiene, Loreta, additional, Zazueta Montiel, Beatriz E, additional, Castillo Ortiz, Angel A, additional, Zamora Tehozol, Erick, additional, Vega Morales, David, additional, Cervántes Rosete, Diana, additional, Martín Nares, Eduardo, additional, Rodriguez Reyna, Tatiana S, additional, Rull Gabayet, Marina, additional, Alpízar Rodríguez, Deshiré, additional, Irazoque, Fedra, additional, Jimenez, Xochitl, additional, Geurts van Bon, Lenny, additional, Zijlstra, Theo, additional, Hoekstra, Monique, additional, Al Adhoubi, Nasra, additional, Salim, Babur, additional, Giraldo, Enrique, additional, Salinas, Ariel, additional, Ugarte Gil, Manuel, additional, Nowakowski, Jarosław, additional, Conway, Richard, additional, Flood, Rachael, additional, McCarthy, Geraldine, additional, Felea, Ioana, additional, Filipescu, Ileana, additional, Rednic, Simona, additional, Groseanu, Laura, additional, Tamas, Maria M, additional, Mlynarikova, Vanda, additional, Skamlova, Martina, additional, Zlnay, Martin, additional, Mičeková, Dagmar, additional, Capova, Lubica, additional, Macejova, Zelmira, additional, Šteňová, Emőke, additional, Raffayova, Helena, additional, Belakova, Gabriela, additional, Strakova, Eva, additional, Senčarová, Marieta, additional, Žlnayová, Soňa, additional, Sabová, Anna, additional, Spisakova, Daniela, additional, Oetterová, Mária, additional, Lukacova, Olga, additional, Bakosova, Martina, additional, Hocevar, Alojzija, additional, de la Torre Rubio, Natalia, additional, Alegre Sancho, Juan J, additional, Corteguera Coro, Montserrat, additional, Cobeta Garcia, Juan C, additional, Torres Martin, Maria C, additional, Campos, Jose, additional, Gomez Puerta, Jose A, additional, Yardimci, Gozd K, additional, Akar, Servet, additional, Icacan, Ozan C, additional, ÇELİK, Selda, additional, Vasylets, Viktoriia, additional, Yeoh, Su-Ann, additional, Vandevelde, Claire, additional, Dunt, Sasha, additional, Leeder, Jane, additional, Macphie, Elizabeth, additional, Salerno, Rosaria, additional, Graver, Christine, additional, Williams, Katie, additional, O'Reilly, Sheila, additional, Devine, Kirsty, additional, Tyler, Jennifer, additional, Warner, Elizabeth, additional, Pilcher, James, additional, Patel, Samir, additional, Nikiphorou, Elena, additional, Chadwick, Laura, additional, Jones, Caroline M, additional, Harrison, Beverley, additional, Thornton, Lucy, additional, O'Kane, Diana, additional, Fusi, Lucia, additional, Low, Audrey, additional, Horton, Sarah, additional, Jatwani, Shraddha, additional, Baig, Sara, additional, Bajwa, Hammad, additional, Berglund, Vernon, additional, Dahle, Angela, additional, Dorman, Walter, additional, Hargrove, Jody, additional, Hilton, Maren, additional, Lebedoff, Nicholas, additional, Leonard, Susan, additional, Morgan, Jennifer, additional, Pfeifer, Emily, additional, Skemp, Archibald, additional, Wilson, Jeffrey, additional, Wolff, Anne, additional, Cepeda, Eduardo, additional, Todd, Derrick, additional, Hare, Denise, additional, Calabrese, Cassandra, additional, Adams, Christopher, additional, Khosroshahi, Arezou, additional, Kilian, Adam, additional, White, Douglas, additional, Winter, Melanie, additional, Fields, Theodore, additional, Siegel, Caroline, additional, Daver, Nicole, additional, Harvey, Melissa, additional, Kramer, Neil, additional, Lamore, Concetta, additional, Hogarty, Suneya, additional, Yeter, Karen, additional, Siddique, Faizah, additional, Ban, Byung, additional, Tanner, Tamar, additional, Ruderman, Eric, additional, Davis, William, additional, Quinet, Robert, additional, Scopelitis, Evangeline, additional, Toribio, Karen, additional, Webb Detiege, Tameka, additional, Zakem, Jerald, additional, Abbass, Khurram, additional, Kepecs, Gilbert, additional, Miranda, Lilliam, additional, Guma, Michael, additional, Haikal, Ammar, additional, Mody, Sushama, additional, Mueller, Daric, additional, Jayatilleke, Arundathi, additional, Zell, JoAnn, additional, Bays, Alison, additional, Dao, Kathryn, additional, Ezzati, Fatemeh, additional, Parks, Deborah, additional, Karp, David, additional, and Quiceno, Guillermo, additional

Published
2022
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12. Clinical and Serological Features in Latin American IgG4-Related Disease Patients Differ According to Sex, Ethnicity, and Clinical Phenotype

Author

Martín-Nares, Eduardo, primary, Baenas, Diego Federico, additional, Cuellar Gutiérrez, María Carolina, additional, Hernández-Molina, Gabriela, additional, Ortiz, Alberto Christian, additional, Neira, Oscar, additional, Gutiérrez, Miguel A., additional, Calvo, Romina, additional, Saad, Emanuel José, additional, Elgueta Pinochet, Sergio, additional, Gallo, Jesica, additional, Herrera Moya, Alejandra, additional, Mansilla Aravena, Bellanides Agustina, additional, Crespo Espíndola, María Elena, additional, Cairoli, Ernesto, additional, Bertoli, Ana María, additional, Córdoba, Mercedes, additional, Wurmann Kiblisky, Pamela, additional, Basualdo Arancibia, Washington Javier, additional, Badilla Piñeiro, María Natalia, additional, Gobbi, Carla Andrea, additional, Berbotto, Guillermo Ariel, additional, Pisoni, Cecilia N., additional, Juárez, Vicente, additional, Cosatti, Micaela Ana, additional, Aste, Nora María, additional, Airoldi, Carla, additional, Llanos, Carolina, additional, Vergara Melian, Cristian Fabián, additional, Erlij Opazo, Daniel, additional, Goecke, Annelise, additional, Pastenes Montaño, Paula Andrea, additional, Tate, Patricio, additional, Pirola, Juan Pablo, additional, Stange Núñez, Lilith, additional, Burgos, Paula I., additional, Mezzano Robinson, María Verónica, additional, Michalland H., Susana, additional, Silva Labra, Francisco, additional, Labarca Solar, Cristián Humberto, additional, Lencina, María Verónica, additional, Izquierdo Loaiza, Jorge Hernán, additional, Del Castillo Gil, David Julián, additional, Caeiro, Francisco, additional, and Paira, Sergio, additional

Published
2022
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13. Outcomes of COVID-19 in patients with primary systemic vasculitis or polymyalgia rheumatica from the COVID-19 Global Rheumatology Alliance physician registry: a retrospective cohort study

Author

Sattui, Sebastian E, primary, Conway, Richard, additional, Putman, Michael S, additional, Seet, Andrea M, additional, Gianfrancesco, Milena A, additional, Beins, Kaley, additional, Hill, Catherine, additional, Liew, David, additional, Mackie, Sarah L, additional, Mehta, Puja, additional, Neill, Lorna, additional, Gomez, Gimena, additional, Salinas, Maria Isabel Haye, additional, Maldonado, Federico Nicolas, additional, Mariz, Henrique Ataide, additional, de Sousa Studart, Samia Araujo, additional, Araujo, Nafice Costa, additional, Knight, Ann, additional, Rozza, Davide, additional, Quartuccio, Luca, additional, Samson, Maxime, additional, Bally, Stéphane, additional, Maria, Alexandre TJ, additional, Chazerain, Pascal, additional, Hasseli, Rebecca, additional, Müller-Ladner, Ulf, additional, Hoyer, Bimba F, additional, Voll, Reinhard, additional, Torres, Rita Pinheiro, additional, Luis, Mariana, additional, Ribeirio, Sandra Lucia Euzebio, additional, Al-Emadi, Samar, additional, Sparks, Jeffrey A, additional, Hsu, Tiffany Y-T, additional, D’Silva, Kristin M, additional, Patel, Naomi J, additional, Wise, Leanna, additional, Gilbert, Emily, additional, Almada, Maria Valenzuela, additional, Duarte-García, Alí, additional, Ugarte-Gil, Manuel, additional, Jacobsohn, Lindsay, additional, Izadi, Zara, additional, Strangfeld, Anja, additional, Mateus, Elsa F, additional, Hyrich, Kimme L, additional, Gossec, Laure, additional, Carmona, Loreto, additional, Lawson-Tovey, Saskia, additional, Kearsley-Fleet, Lianne, additional, Schaefer, Martin, additional, Sirotich, Emily, additional, Hausmann, Jonathan S, additional, Sufka, Paul, additional, Bhana, Suleman, additional, Liew, Jean W, additional, Grainger, Rebecca, additional, Machado, Pedro M, additional, Wallace, Zachary S, additional, Yazdany, Jinoos, additional, Robinson, Philip C, additional, Dahou, Brahim, additional, Rath, Eva, additional, Piette, Yves, additional, Devinck, Mieke, additional, Maeyaert, Bea, additional, Machado Ribeiro, Francinne, additional, Euzebio Ribeiro, Sandra Lucia, additional, Pinheiro, Marcelo, additional, Quintana, Rosana, additional, Gómez, Gimena, additional, Roberts, Karen, additional, Baez, Roberto Miguel, additional, Castro Coello, Vanessa, additional, Haye Salinas, María J., additional, Reyes Torres, Alvaro Andres, additional, Alle, Gelsomina, additional, Tanten, Romina, additional, Maldonado Ficco, Hernán, additional, Nieto, Romina, additional, Gobbi, Carla, additional, Tissera, Yohana, additional, Pisoni, Cecilia, additional, Paula, Alba, additional, Albiero, Juan Alejandro, additional, Schmid, Maria Marcela, additional, Cosatti, Micaela, additional, Gamba, Maria Julieta, additional, Leandro, Carlevaris, additional, Cusa, María Alejandra, additional, German, Noelia, additional, Bellomio, Veronica, additional, Takashima, Lorena, additional, Pera, Mariana, additional, Cogo, Karina, additional, Gálvez Elkin, Maria Soledad, additional, Medina, María Alejandra, additional, Savio, Veronica, additional, Rojas Tessel, Ivana Romina, additional, Perez Alamino, Rodolfo, additional, Werner, Marina Laura, additional, Ornella, Sofía, additional, Casalla, Luciana, additional, de la Vega, Maria, additional, Severina, María, additional, García, Mercedes, additional, Gonzalez Lucero, Luciana, additional, Romeo, Cecilia, additional, Moyano, Sebastián, additional, Barbich, Tatiana, additional, Bertoli, Ana, additional, Baños, Andrea, additional, Petruzzelli, Sandra, additional, Matellan, Carla, additional, Conti, Silvana, additional, Lazaro, Ma. Alicia, additional, Rodriguez Gil, Gustavo Fabián, additional, Risueño, Fabian, additional, Quaglia, Maria Isabel, additional, Scafati, Julia, additional, Cuchiaro, Natalia Lili, additional, Rebak, Jonathan Eliseo, additional, Pineda, Susana Isabel, additional, Calvo, María Elena, additional, Picco, Eugenia, additional, Gallino Yanzi, Josefina, additional, Maid, Pablo, additional, Guaglianone, Debora, additional, Morbiducci, Julieta Silvana, additional, Porta, Sabrina, additional, Herscovich, Natalia, additional, Velasco Zamora, José Luis, additional, Kisluk, Boris, additional, Castaños Menescardi, Maria Sol, additional, Gallo, Rosana, additional, Martire, María Victoria, additional, Maldini, Carla, additional, Goizueta, Cecilia, additional, de la Vega Fernandez, Sabrina Solange, additional, Aeschlimann, Carolina, additional, Subils, Gisela, additional, Ibáñez, Sebastián, additional, Chassin-Trubert, Anne-Marie, additional, Dong, Lingli, additional, Cajas, Lui, additional, Barešic, Marko, additional, Anic, Branimir, additional, Culo, Melanie-Ivana, additional, Pavelic, Tea Ahel, additional, Kovacevic Stranski, Kristina, additional, Karanovic, Boris, additional, Vencovsky, Jiri, additional, Píchová, Marta, additional, Filkova, Maria, additional, Hamoud, Hesham, additional, Vassilopoulos, Dimitrios, additional, Guzman Melgar, Gabriela Maria, additional, So, Ho, additional, Király, Márta, additional, Vojdanian, Mahdi, additional, Balbir-Gurman, Alexandra, additional, Abutiban, Fatemah, additional, Zepa, Julija, additional, Bulina, Inita, additional, Bukauskiene, Loreta, additional, Zaueta, Beatriz, additional, Castillo Ortiz, Angel Alejandro, additional, Zamora Tehozol, Erick, additional, Vega, David, additional, Cervántes Rosete, Diana, additional, Martín Nares, Eduardo, additional, Rodriguez-Reyna, Tatiana Sofia, additional, Rull Gabayet, Marina, additional, Alpízar-Rodríguez, Deshiré, additional, Irazoque, Fedra, additional, Jimenez, Xochitl, additional, Geurts-van Bon, Lenny, additional, Zijlstra, Theo, additional, Hoekstra, Monique, additional, Al-Adhoubi, Nasra, additional, Salim, Babur, additional, Giraldo, Enrique, additional, Salinas, Ariel, additional, Nowakowski, Jaroslaw, additional, Flood, Rachael, additional, McCarthy, Geraldine, additional, Felea, Ioana, additional, Filipescu, Ileana, additional, Rednic, Simona, additional, Groseanu, Laura, additional, Tamas, Maria Magdelena, additional, Mlynarikova, Vanda, additional, Skamlova, Martina, additional, Zlnay, Martin, additional, Miceková, Dagmar, additional, Capova, Lubica, additional, Macejova, Zelmira, additional, Štenová, Emoke, additional, Raffayova, Helena, additional, Belakova, Gabriela, additional, Strakova, Eva, additional, Sencarová, Marieta, additional, Žlnayová, Sona, additional, Anna Sabová, Anna, additional, Spisakova, Daniela, additional, Oetterová, Mária, additional, Lukacova, Olga, additional, Bakosova, Martina, additional, Hocevar, Alojzija, additional, de la Torre-Rubio, Natalia, additional, Alegre Sancho, Juan José, additional, Corteguera Coro, Montserrat, additional, Cobeta Garcia, Juan Carlos, additional, Torres Martin, Maria Carmen, additional, Campos, Jose, additional, Gomez Puerta, Jose A, additional, Yardimci, Gozd Kubra, additional, Akar, Servet, additional, Icacan, Ozan Cemal, additional, Çelik, Selda, additional, Vasylets, Viktoriia, additional, Yeoh, Su-Ann, additional, Vandevelde, Claire, additional, Dunt, Sasha, additional, Leeder, Jane, additional, Macphie, Elizabeth, additional, Salerno, Rosaria, additional, Graver, Christine, additional, Williams, Katie, additional, O'Reilly, Sheila, additional, Devine, Kirsty, additional, Tyler, Jennifer, additional, Warner, Elizabeth, additional, Pilcher, James, additional, Patel, Samir, additional, Nikiphorou, Elena, additional, Chadwick, Laura, additional, Jones, Caroline Mulvaney, additional, Harrison, Beverley, additional, Thornton, Lucy, additional, O'Kane, Diana, additional, Fusi, Lucia, additional, Low, Audrey, additional, Horton, Sarah, additional, Jatwani, Shraddha, additional, Baig, Sara, additional, Bajwa, Hammad, additional, Berglund, Vernon, additional, Dahle, Angela, additional, Dorman, Walter, additional, Hargrove, Jody, additional, Hilton, Maren, additional, Lebedoff, Nicholas, additional, Leonard, Susan, additional, Morgan, Jennifer, additional, Pfeifer, Emily, additional, Skemp, Archibald, additional, Wilson, Jeffrey, additional, Wolff, Anne, additional, Cepeda, Eduardo, additional, D'Silva, Kristin, additional, Hsu, Tiffany, additional, Patel, Naomi, additional, Sparks, Jeffrey, additional, Todd, Derrick, additional, Wallace, Zachary, additional, Hare, Denise, additional, Calabrese, Cassandra, additional, Adams, Christopher, additional, Khosroshahi, Arezou, additional, Kilian, Adam, additional, White, Douglas, additional, Winter, Melanie, additional, Fields, Theodore, additional, Siegel, Caroline, additional, Daver, Nicole, additional, Harvey, Melissa, additional, Kramer, Neil, additional, Lamore, Concetta, additional, Hogarty, Suneya, additional, Yeter, Karen, additional, Siddique, Faizah, additional, Ban, Byung, additional, Tanner, Tamar, additional, Ruderman, Eric, additional, Davis, William, additional, Quinet, Robert, additional, Scopelitis, Evangeline, additional, Toribio Toribio, Karen, additional, Webb-Detiege, Tameka, additional, Zakem, Jerald, additional, Abbass, Khurram, additional, Kepecs, Gilbert, additional, Miranda, Lilliam, additional, Guma, Michael, additional, Haikal, Ammar, additional, Mody, Sushama, additional, Mueller, Daric, additional, Jayatilleke, Arundathi, additional, Zell, JoAnn, additional, Bays, Alison, additional, Dao, Kathryn, additional, Fatemeh, Ezzati, additional, Parks, Deborah, additional, Karp, David, additional, and Quiceno, Guillermo, additional

Published
2021
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14. Does hydroxychloroquine improve patient reported outcomes in patients with lupus?

Author

Jolly, Meenakshi, primary, Sehgal, Vinay, additional, Arora, Shilpa, additional, Azizoddin, Desiree, additional, Pinto, Benzeeta, additional, Sharma, Aman, additional, Devilliers, Herve, additional, Inoue, Mitsuyo, additional, Toloza, Sergio, additional, Bertoli, Ana, additional, Blazevic, Ivana, additional, Vilá, Luis M, additional, Moldovan, Ioana, additional, Torralba, Karina D, additional, Mazzoni, Davide, additional, Cicognani, Elvira, additional, Hasni, Sarfaraz, additional, Goker, Berna, additional, Haznedaroglu, Seminur, additional, Bourre-Tessier, Josiane, additional, Navarra, Sandra V, additional, Clarke, Ann, additional, Weisman, Michael, additional, Wallace, Daniel, additional, and Mok, Chi Chiu, additional

Published
2021
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15. Prevalence and Correlates of Metabolic Syndrome in Patients With Rheumatoid Arthritis in Argentina

Author

Salinas, María Jezabel Haye, Bertoli, Ana María, Lema, Luís, Saucedo, Carla, Rosa, Javier, Quintana, Rosana, Bellomio, Verónica, Agüero, Santiago, Spindler, Walter, Tamborenea, Natalia, Schimid, Marcela, Ceccato, Federico, Sala, Jose Pablo, Paira, Sergio, Spindler, Alberto, Soriano, Enrique R., Pons Estel, Bernardo A., Caeiro, Francisco, Alvarellos, Alejandro, and Saurit, Verónica

Published
2013
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18. Contributing Authors

Author

Abdou, Nabih I., primary, Adler, Matthew, additional, Ahearn, Joseph M., additional, Alarcón, Graciela S., additional, Al-Maini, Mustafa, additional, Askanase, Anca D., additional, Balow, James E., additional, Banchereau, Jacques, additional, Bertoli, Ana M., additional, and Birmingham, Dan J., additional

Published
2007
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20. Drivers of Satisfaction With Care for Patients With Lupus

Author

Jolly, Meenakshi, primary, Sethi, Bhavika, additional, O'Brien, Courtney, additional, Sequeira, Winston, additional, Block, Joel A., additional, Toloza, Sergio, additional, Bertoli, Ana, additional, Blazevic, Ivana, additional, Vilá, Luis M., additional, Moldovan, Ioana, additional, Torralba, Karina D., additional, Cicognani, Elvira, additional, Mazzoni, Davide, additional, Hasni, Sarfaraz, additional, Goker, Berna, additional, Haznedaroglu, Seminur, additional, Bourre‐Tessier, Josiane, additional, Navarra, Sandra V., additional, Mok, Chi Chiu, additional, Clarke, Ann, additional, Weisman, Michael, additional, and Wallace, Daniel, additional

Published
2019
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33. 271 Frequency of neonatal lupus in reference centers in the management of pregnancy and autoimmune diseases

Author

Maldini, Carla, primary, Otaduy, Cintia, additional, Mollerach, Florencia Beatriz, additional, Scolnik, Marina, additional, Virasoro, Belen Maria, additional, Pisoni, Cecilia, additional, Croce, Mercedes, additional, Hu, Maria, additional, Camargo Serrudo, Fabiola Natalia, additional, Dubinsky, Diana, additional, Leon, María de la Paz, additional, Bellomio, Veronica, additional, Rengifo, Daniela Flores, additional, Kerzberg, Eduardo, additional, Guzzanti, Fernanda, additional, Civit, Emma E, additional, Bertoli, Ana, additional, Lopez Perez, Maria Jose, additional, Escobar, Maximiliano Machado, additional, Savio, Veronica, additional, Babini, Alejandra, additional, Alvarez, Cecilia, additional, Saurit, Verónica, additional, Morales, Rosa Serrano, additional, Lascano, Cruz, additional, Danielsen, María Constanza, additional, Etcheverry, Mayra, additional, Estevez, Adrian, additional, Werner, Marina, additional, Onetti, Laura, additional, Alba, Paula, additional, and Gobbi, Carla, additional

Published
2019
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34. Drivers of satisfaction with care in lupus

Author

Toloza, Sergio, JOLLY, MEENAKSHI, Wallace, Daniel, Weissman, Michael, Clarke, Ann, Mok, Chi, Navarra, Sandra, BourreTessier, Josiane, HAZNEDAROĞLU, ŞEMİNUR, Hasni, Sarfaraz, Cicognani, Elvira, Mazzoni, Davide, Torrolba, Karina, Moldovan, Ioana, Vila, Luis, Blazevic, Ivana, Bertoli, Ana, BLOCK, JA, Sequeira, Winston, Sethi, Bhavika, and GÖKER, BERNA

Published
2017

35. Drivers of Satisfaction with Care in Lupus

Author

GÖKER, BERNA, HAZNEDAROĞLU, ŞEMİNUR, Moldovan, Ioana, Toloza, Sergio, Block, Joel A., Nika, Ailda, Sequeira, Winston, Clarke, Ann, Sethi, Bhavika, Mok, Chi Chiu, Navarra, Sandra V., Bourre-Tessier, Josiane, Hasni, Sarfaraz, Cicognani, Elvira, Mazzoni, Davide, Torralba, Karina, Vila, Luis M., Blazevic, Ivana, Bertoli, Ana, Jolly, Meenakshi, Wallace, Daniel J., and Weisman, Michael

Published
2017

36. Sex Differences in Quality of Life in Patients With Systemic Lupus Erythematosus

Author

Jolly, Meenakshi, primary, Sequeira, Winston, additional, Block, Joel A., additional, Toloza, Sergio, additional, Bertoli, Ana, additional, Blazevic, Ivanna, additional, Vila, Luis M., additional, Moldovan, Ioana, additional, Torralba, Karina D., additional, Mazzoni, Davide, additional, Cicognani, Elvira, additional, Hasni, Sarfaraz, additional, Goker, Berna, additional, Haznedaroglu, Seminur, additional, Bourre‐Tessier, Josiane, additional, Navarra, Sandra V., additional, Mok, Chi Chiu, additional, Weisman, Michael, additional, Clarke, Ann E., additional, Wallace, Daniel, additional, and Alarcón, Graciela, additional

Published
2018
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37. Sex Differences in Quality of Life in Patients With Systemic Lupus Erythematosus.

Author

Jolly, Meenakshi, Sequeira, Winston, Block, Joel A., Toloza, Sergio, Bertoli, Ana, Blazevic, Ivanna, Vila, Luis M., Moldovan, Ioana, Torralba, Karina D., Mazzoni, Davide, Cicognani, Elvira, Hasni, Sarfaraz, Goker, Berna, Haznedaroglu, Seminur, Bourre‐Tessier, Josiane, Navarra, Sandra V., Mok, Chi Chiu, Weisman, Michael, Clarke, Ann E., and Wallace, Daniel

Abstract

Objective: Systemic lupus erythematosus (SLE) predominantly affects women. Clinical phenotype and outcomes in SLE may vary by sex and are further complicated by unique concerns that are dependent upon sex-defined roles. We aimed to describe sex differences in disease-specific quality of life (QoL) assessment scores using the Lupus Patient-Reported Outcome (LupusPRO) tool in a large international study.Methods: Cross-sectional data from 1,803 patients with SLE on demographics, self-identified sex status, LupusPRO, and disease activity were analyzed. The LupusPRO tool has 2 constructs: health-related QoL (HRQoL) and non-HRQoL. Disease activity and damage were evaluated using the Safety of Estrogens in Lupus Erythematosus National Assessment version of the Systemic Lupus Erythematosus Disease Activity Index and the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index, respectively. Nonparametric tests were used to compare QoL and disease activity by sex.Results: A total of 122 men and 1,681 women with SLE participated. The mean age was similar by sex, but the damage scores were greater among men. Men fared worse on the non-HRQoL social support domain than women (P = 0.02). When comparing disease and QoL among men and women ages ≤45 years, men were found to have greater damage and worse social support than women. However, women fared significantly worse on lupus symptoms, cognition, and procreation domains with trends for worse functioning on physical health and pain-vitality domains.Conclusion: In the largest study of a diverse group of SLE patients, utilizing a disease-specific QoL tool, sex differences in QoL were observed on both HRQoL and non-HRQoL constructs. Although men performed worse in the social support domain, women (especially those in the reproductive age group) fared worse in other domains. These observations may assist physicians in appropriately addressing QoL issues in a sex-focused manner. [ABSTRACT FROM AUTHOR]

Published
2019
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39. Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA

Author

Zhao, Jian, Giles, Brendan M., Taylor, Rhonda L., Yette, Gabriel A., Lough, Kara M., Han Leng, Ng, Abraham, Lawrence J., Hui, Wu, Kelly, Jennifer A., Glenn, Stuart B., Adler, Adam J., Williams, Adrienne H., Comeau, Mary E., Ziegler, Julie T., Marion, Miranda, Alarcón Riquelme, Marta E., Alarcón, Graciela S., Anaya, Juan Manuel, Bae, Sang Cheol, Kim, Dam, Lee, Hye Soon, Criswell, Lindsey A., Freedman, Barry I., Gilkeson, Gary S., Guthridge, Joel M., Jacob, Chaim O., James, Judith A., Kamen, Diane L., Merrill, Joan T., Sivils, Kathy Moser, Niewold, Timothy B., Petri, Michelle A., Ramsey Goldman, Rosalind, Reveille, John D., Scofield, R. Hal, Stevens, Anne M., Vilá, Luis M., Vyse, Timothy J., Kaufman, Kenneth M., Harley, John B., Langefeld, Carl D., Gaffney, Patrick M., Brown, Elizabeth E., Edberg, Jeffrey C., Kimberly, Robert P., Ulgiati, Daniela, Tsao, Betty P., Boackle, Susan A., Frostegård, Johan, Truedsson, Lennart, De Ramón, Enrique, Sabio, José M., González Escribano, María F., Martin, Javier, Ortego Centeno, Norberto, Callejas, José Luis, Sánchez Román, Julio, D'Alfonso, Sandra, Migliarese, Sergio, Sebastiani, Gian Domenico, Galeazzi, Mauro, Witte, Torsten, Lauwerys, Bernard R., Endreffy, Emoke, Kovács, László, Vasconcelos, Carlos, Da Silva, Berta Martins, Scherbarth, R., Marino, Pilar C., Motta, Estela L., Gamron, Susana, Drenkard, Cristina, Menso, Emilia, Allievi, Alberto, Tate, Guillermo A., Presas, Jose L., Palatnik, Simon A., Abdala, Marcelo, Bearzotti, Mariela, Alvarellos, Alejandro, Caeiro, Francisco, Bertoli, Ana, Paira, Sergio, Roverano, Susana, Graf, Cesar E., Bertero, Estela, Caprarulo, Cesar, Buchanan, Griselda, Guillerón, Carolina, Grimaudo, Sebastian, Manni, Jorge, Catoggio, Luis J., Soriano, Enrique R., Santos, Carlos D., Prigione, Cristina, Ramos, Fernando A., Navarro, Sandra M., Berbotto, Guillermo A., Jorfen, Marisa, Romero, Elisa J., Garcia, Mercedes A., Marcos, Juan C., Marcos, Ana I., Perandones, Carlos E., Eimon, Alicia, Parque, Sanatorio, Battagliotti, Cristina G., Acevedo, Eduardo, Cucho, Mariano, De La Torre, Ignacio García, Ríos, Mario Cardiel, Moctezuma, José Francisco, and Ceceña, Marco Maradiaga

Subjects
Genetics and Molecular Biology (all), CR1 protein, human, Anti-nuclear antibody, Intron, Pathogenesis, Complement receptor, Real time polymerase chain reaction, Procedures, Biochemistry, Haplotype, Basic and Translational Research, Systemic lupus erythematosus, Messenger RNA, 3. Good health, Blood, Human, Genotype, Immunology, Case control study, B-Lymphocyte Subsets, Single-nucleotide polymorphism, Major clinical study, Biosynthesis, Risk Assessment, Article, General Biochemistry, Genetics and Molecular Biology, Double stranded DNA antibody, 03 medical and health sciences, Gene Polymorphism, Rheumatology, Genetics, Humans, Polymorphism, Autoantibodies, B cells, Genetic predisposition, Systemic, Genetic Variation, DNA, medicine.disease, 030104 developmental biology, Case-Control Studies, Receptors, Complement 3b, Receptors, Complement 3d, Complement component C3b receptor, Transcription factor, Transcription Factors, 0301 basic medicine, Unclassified drug, Complement receptor 2, Systemic Lupus Erythematosus, Adolescent, Adult, Antibodies, Antinuclear, Genetic Predisposition to Disease, Haplotypes, Lupus Erythematosus, Systemic, Middle Aged, Phenotype, Polymorphism, Single Nucleotide, Young Adult, Immunology and Allergy, Medicine (all), Biochemistry, Genetics and Molecular Biology (all), Complement receptor 1, Antinuclear, Receptors, Flow cytometry, Middle aged, Priority journal, Risk assessment, Allele, biology, Single Nucleotide, Complement component C3d receptor, Chromatin immunoprecipitation, Transcription factor CTCF, Antibodies, DNA protein complex, Antinuclear antibody, medicine, Genetic variation, Lupus erythematosus, B lymphocyte, Lupus Erythematosus, Complement 3d, Complement 3b, Molecular biology, Single nucleotide polymorphism, Minor allele frequency, Metabolism, Genetic association, Genetic variability, Gel mobility shift assay, biology.gene, Controlled study
Abstract

Objectives Systemic lupus erythematosus (SLE; OMIM 152700) is characterised by the production of antibodies to nuclear antigens. We previously identified variants in complement receptor 2 (CR2/CD21) that were associated with decreased risk of SLE. This study aimed to identify the causal variant for this association. Methods Genotyped and imputed genetic variants spanning CR2 were assessed for association with SLE in 15 750 case-control subjects from four ancestral groups. Allele-specific functional effects of associated variants were determined using quantitative real-time PCR, quantitative flow cytometry, electrophoretic mobility shift assay (EMSA) and chromatin immunoprecipitation (ChIP)-PCR. Results The strongest association signal was detected at rs1876453 in intron 1 of CR2 (pmeta=4.2×10-4, OR 0.85), specifically when subjects were stratified based on the presence of dsDNA autoantibodies (case-control pmeta=7.6×10-7, OR 0.71; case-only pmeta=1.9×10-4, OR 0.75). Although allele-specific effects on B cell CR2 mRNA or protein levels were not identified, levels of complement receptor 1 (CR1/CD35) mRNA and protein were significantly higher on B cells of subjects harbouring the minor allele (p=0.0248 and p=0.0006, respectively). The minor allele altered the formation of several DNA protein complexes by EMSA, including one containing CCCTC-binding factor (CTCF), an effect that was confirmed by ChIP-PCR. Conclusions These data suggest that rs1876453 in CR2 has long-range effects on gene regulation that decrease susceptibility to lupus. Since the minor allele at rs1876453 is preferentially associated with reduced risk of the highly specific dsDNA autoantibodies that are present in preclinical, active and severe lupus, understanding its mechanisms will have important therapeutic implications.

Published
2016

40. Efficacité à court terme des infiltrations locales de corticoïdes réalisées « à l’aveugle » versus « sous contrôle échographique » dans le traitement de la ténosynovite chez les patients atteints d’arthrite inflammatoire chronique : étude comparative randomisée

Author

Gutierrez, Marwin, primary, Di Matteo, Andrea, additional, Rosemffet, Marcos, additional, Cazenave, Tomas, additional, Rodriguez-Gil, Gustavo, additional, Hernandez Diaz, Cristina, additional, Ventura Rios, Lucio, additional, Zamora, Natalia, additional, del Carmen Gonzalez Guzman, Maria, additional, Carrillo, Ignacio, additional, Okano, Tadashi, additional, Salaffi, Fausto, additional, Pineda, Carlos, additional, Aliste, Marta, additional, Alva, Magaly, additional, Aragón-Laínez, R.A., additional, Areny, Roser, additional, Audisio, Marcelo, additional, Bertoli, Ana, additional, Bouffard, José Antonio, additional, Caballero-Uribe, Carlo Vinicio, additional, Camacho, Walter, additional, Díaz-Coto, José Francisco, additional, Filippucci, Emilio, additional, Flores, Víctor, additional, Hoffman, Fritz, additional, Kurslikova, María, additional, Mendonça, José Alexander, additional, Moya, Carlos, additional, Mora, Claudia, additional, Muñoz-Louis, Roberto, additional, Py, Guillermo Enrique, additional, Quintero, Maritza, additional, Rodríguez Henríquez, Pedro, additional, Saavedra, Jorge, additional, Santiago, Lida, additional, Sedano, Oscar, additional, Solano, Carla, additional, Urioste, Lorena, additional, Villota, Orlando, additional, Ceron, Carmen, additional, Saaibi, Diego, additional, Diaz, Mario, additional, and Roth, Johannes, additional

Published
2016
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42. Simple Disease Assessment for People with Lupus Erythematosus

Author

Mok, Chi Chiu, Clarke, Ann E., Weisman, Michael H., Wallace, Daniel, Navarra, Sandra V., Bourre-Tessier, Josiane, GÖKER, BERNA, Torralba, Katrina D., Moldovan, Ioana, Blazevic, Ivana, Vila, Luis M., Bertoli, Ana M., Toloza, Sergio, Sequeira, Winston, Jolly, Meenakshi, and Block, Joel A.

Published
2014

44. Preferential Binding to Elk-1 by SLE-Associated IL10 Risk Allele Upregulates IL10 Expression

Author

Sakurai, Daisuke, Zhao, Jian, Deng, Yun, Kelly, Jennifer A., Brown, Elizabeth E., Harley, John B., Bae, Sang Cheol, Alarcn-Riquelme, Marta E., Edberg, Jeffrey C., Kimberly, Robert P., Ramsey-Goldman, Rosalind, Petri, Michelle A., Reveille, John D., Vilá, Luis M., Alarcón, Graciela S., Kaufman, Kenneth M., Vyse, Timothy J., Jacob, Chaim O., Gaffney, Patrick M., Sivils, Kathy Moser, James, Judith A., Kamen, Diane L., Gilkeson, Gary S., Niewold, Timothy B., Merrill, Joan T., Scofield, R. Hal, Criswell, Lindsey A., Stevens, Anne M., Boackle, Susan A., Kim, Jae Hoon, Choi, Jiyoung, Pons-Estel, Bernardo A., Freedman, Barry I., Anaya, Juan Manuel, Martin, Javier, Yu, C. Yung, Chang, Deh Ming, Song, Yeong Wook, Langefeld, Carl D., Chen, Weiling, Grossman, Jennifer M., Cantor, Rita M., Hahn, Bevra H., Tsao, Betty P., Frostegård, Johan, Truedsson, Lennart, de Ramón, Enrique, Sabio, José M., Ortego-Centeno, Norberto, CAllejas, José Luis, González-Escribano, María F., Sánchez-Román, Julio, D'Alfonso, Sandra, Migliarese, Sergio, Sebastiani, Gian Domenico, Galeazzi, Mauro, Witte, Torsten, Lauwerys, Bernard R., Endreffy, Emoke, Kovács, László, Vasconcelos, Carlos, da Silva, Berta Martins, Scherbarth, Hugo R., Marino, Pilar C., Motta, Estela L., Gamron, Susana, Drenkard, Cristina, Menso, Emilia, Allievi, Alberto, Tate, Guillermo A., Presas, Jose L., Palatnik, Simon A., Abdala, Marcelo, Bearzotti, Mariela, Alvarellos, Alejandro, Caeiro, Francisco, Bertoli, Ana, Paira, Sergio, Roverano, Susana, Graf, Cesar E., Bertero, Estela, Caprarulo, Cesar, Buchanan, Griselda, Guillerón, Carolina, Grimaudo, Sebastian, Manni, Jorge, Catoggio, Luis J., Soriano, Enrique R., Santos, Carlos D., Prigione, Cristina, Ramos, Fernando A., Navarro, Sandra M., Berbotto, Guillermo A., Jorfen, Marisa, Romero, Elisa J., Garcia, Mercedes A., Marcos, Juan C., Marcos, Ana I., Perandones, Carlos E., Eimon, Alicia, Parque, Sanatorio, Battagliotti, Cristina G., Acevedo, Eduardo, Cucho, Mariano, de la Torre, Ignacio García, Ríos, Mario Cardiel, Moctezuma, José Francisco, and Ceceña, Marco Maradiaga

Subjects
Cancer Research, medicine.medical_treatment, Genome-wide association study, Gene, Disease predisposition, 0302 clinical medicine, Interleukin 10, immune system diseases, Lupus Erythematosus, Systemic, Disease activity, skin and connective tissue diseases, Genetics (clinical), Regulation of gene expression, 0303 health sciences, TGranscription factor Elk 1, Hispanic or Latino, Interleukin-10, Up-Regulation, 3. Good health, Cytokine, Research Article, Protein Binding, Genotype, lcsh:QH426-470, Inmunología, Single-nucleotide polymorphism, Down regulation, Biology, Polymorphism, Single Nucleotide, White People, 03 medical and health sciences, Asian People, Enfermedades autoinmunes, Lupus eritematoso sistémico, Genetics, medicine, Humans, Genetic Predisposition to Disease, Electrophoretic mobility shift assay, Gene cluster, Allele, Molecular Biology, Alleles, Ecology, Evolution, Behavior and Systematics, ets-Domain Protein Elk-1, 030304 developmental biology, Lupus erythematosus, medicine.disease, Enfermedades, Introns, lcsh:Genetics, Binding affinity, Gene Expression Regulation, Haplotypes, Immunology, Controlled study, Genome-Wide Association Study, 030215 immunology
Abstract

Immunoregulatory cytokine interleukin-10 (IL-10) is elevated in sera from patients with systemic lupus erythematosus (SLE) correlating with disease activity. The established association of IL10 with SLE and other autoimmune diseases led us to fine map causal variant(s) and to explore underlying mechanisms. We assessed 19 tag SNPs, covering the IL10 gene cluster including IL19, IL20 and IL24, for association with SLE in 15,533 case and control subjects from four ancestries. The previously reported IL10 variant, rs3024505 located at 1 kb downstream of IL10, exhibited the strongest association signal and was confirmed for association with SLE in European American (EA) (P = 2.7×10−8, OR = 1.30), but not in non-EA ancestries. SNP imputation conducted in EA dataset identified three additional SLE-associated SNPs tagged by rs3024505 (rs3122605, rs3024493 and rs3024495 located at 9.2 kb upstream, intron 3 and 4 of IL10, respectively), and SLE-risk alleles of these SNPs were dose-dependently associated with elevated levels of IL10 mRNA in PBMCs and circulating IL-10 protein in SLE patients and controls. Using nuclear extracts of peripheral blood cells from SLE patients for electrophoretic mobility shift assays, we identified specific binding of transcription factor Elk-1 to oligodeoxynucleotides containing the risk (G) allele of rs3122605, suggesting rs3122605 as the most likely causal variant regulating IL10 expression. Elk-1 is known to be activated by phosphorylation and nuclear localization to induce transcription. Of interest, phosphorylated Elk-1 (p-Elk-1) detected only in nuclear extracts of SLE PBMCs appeared to increase with disease activity. Co-expression levels of p-Elk-1 and IL-10 were elevated in SLE T, B cells and monocytes, associated with increased disease activity in SLE B cells, and were best downregulated by ERK inhibitor. Taken together, our data suggest that preferential binding of activated Elk-1 to the IL10 rs3122605-G allele upregulates IL10 expression and confers increased risk for SLE in European Americans., Author Summary Systemic lupus erythematosus (SLE), a debilitating autoimmune disease characterized by the production of pathogenic autoantibodies, has a strong genetic basis. Variants of the IL10 gene, which encodes cytokine interleukin-10 (IL-10) with known function of promoting B cell hyperactivity and autoantibody production, are associated with SLE and other autoimmune diseases, and serum IL-10 levels are elevated in SLE patients correlating with increased disease activity. In this study, to discover SLE-predisposing causal variant(s), we assessed variants within the genomic region containing IL10 and its gene family member IL19, IL20 and IL24 for association with SLE in case and control subjects from diverse ancestries. We identified SLE-associated SNP rs3122605 located at 9.2 kb upstream of IL10 as the most likely causal variant in subjects of European ancestry. The SLE-risk allele of rs3122605 was dose-dependently associated with elevated IL10 expression at both mRNA and protein levels in peripheral blood samples from SLE patients and controls, which could be explained, at least in part, by its preferential binding to Elk-1, a transcription factor activated in B cells during active disease of SLE patients. Elk-1-mediated IL-10 overexpression could be downregulated by inhibiting activation of mitogen-activated protein kinases, suggesting a potential therapeutic target for SLE.

Published
2013

45. Identification of a new putative functional IL18 gene variant through an association study in systemic lupus erythematosus

Author

Sánchez, Elena, Palomino Morales, Rogelio J., Ortego Centeno, Norberto, Jiménez Alonso, Juan, González Gay, Miguel A., López Nevot, Miguel A., Sánchez Román, Julio, de Ramón, Enrique, González Escribano, M. Francisca, Pons Estel, Bernardo A., D'Alfonso, Sandra, Sebastiani, Gian Domenico, Alarcón Riquelme, Marta E., Martín, Javier, Scherbarth, Hugo R., Marino, Pilar C., Motta, Estela L., Gamron, Susana, Drenkard, Cristina, Menso, Emilia, Allievi, Alberto, Tate, Guillermo A., Presas, Jose L., Palatnik, Simon A., Abdala, Marcelo, Bearzotti, Mariela, Alvarellos, Alejandro, Caeiro, Francisco, Bertoli, Ana, Paira, Sergio, Roverano, Susana, Graf, Cesar E., Bertero, Estela, Caprarulo, Cesar, Buchanan, Griselda, Guillerón, Carolina, Grimaudo, Sebastian, Manni, Jorge, Catoggio, Luis J., Soriano, Enrique R., Santos, Carlos D., Prigione, Cristina, Ramos, Fernando A., Navarro, Sandra M., Berbotto, Guillermo A., Jorfen, Marisa, Romero, Elisa J., Garcia, Mercedes A., Marcos, Juan C, Marcos, Ana I., Perandones, Carlos E., Eimon, Alicia, Battagliotti, Cristina G., Barizzone, Nadia, Galeazzi, Mauro, Danieli, Maria Giovanna, Migliaresi, Sergio, and Bozzolo, Enrica

Subjects
Genotype, European Continental Ancestry Group, Gene Expression, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, White People, Chromosomes, Cell Line, TaqMan, Genetics, Lupus Erythematosus, Systemic, SNP, Humans, Genetic Predisposition to Disease, Allele, Pair 11, Polymorphism, Gene, Molecular Biology, Genetics (clinical), Genetic association, Case-Control Studies, Chromosome Mapping, Chromosomes, Human, Pair 11, Genetic Variation, Interleukin-18, Genome-Wide Association Study, Lupus Erythematosus, Systemic, General Medicine, Single Nucleotide, Immunology, Interleukin 18, Human
Abstract

Interleukin-18 (IL-18) is a proinflammatory cytokine that plays an important role in chronic inflammation and autoimmune disorders. In this study, we aimed to determine the potential role of the IL18 gene in SLE. To define the genetic association of the IL18 and SLE, we have genotyped nine SNPs in an independent set of Spanish cases and controls. The IL18 polymorphisms were genotyped by PCR, using a predeveloped TaqMan allele discrimination assay. Two SNPs were still significant after fine mapping of the IL18 gene. The SNP (rs360719) surviving correction for multiple tests was genotyped in two replication cohorts from Italy and Argentina. After the analysis, a significance with rs360719 C-allele remained across the sets and after the meta-analysis (Pooled OR = 1.37, 95% CI 1.21-1.54, combined P = 3.8E-07, Pc = 1.16E-06). Quantitative real-time PCR was performed to assess IL18 mRNA expression in PBMC from subjects with different IL18 rs360719 genotypes. We tested the effect of the IL18 rs360719 polymorphism on the transcription of IL18 by electrophoretic mobility shift assay and western blot. We found a significant increase in the relative expression of IL18 mRNA in individuals carrying the rs360719 C-risk allele; in addition we show that the polymorphism creates a binding site for the transcriptional factor OCT-1. These findings suggest that the novel IL18 rs360719 variant may play an important role in determining the susceptibility to SLE and it could be a key factor in the expression of the IL18 gene.

Published
2009

48. Prevalence and Correlates of Metabolic Syndrome in Patients With Rheumatoid Arthritis in Argentina.

Author

Haye Salinas, María Jezabel, Bertoli, Ana María, Lema, Luís, Saucedo, Carla, Rosa, Javier, Quintana, Rosana, Bellomio, Verónica, Agüero, Santiago, Spindler, Walter, Tamborenea, Natalia, Schimid, Marcela, Ceecato, Federico, Sala, Jose Pablo, Paira, Sergio, Spindler, Alberto, Soriano, Enrique R., Pons Estel, Bernardo A., Caeiro, Francisco, Alvarellos, Alejandro, and Saurit, Verónica

Published
2013
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49. PREVALENCIA DE DISLIPEMIA Y RIESGO CARDIOVASCULAR ELEVADO EN PACIENTES CON ARTRITIS REUMATOIDE.

Author

HAYE SALINAS, MARÍA JEZABEL, BERTOLI, ANA M., LEMA, LUIS, SAUCEDO, CARLA, ROSA, JAVIER, QUINTANA, ROSANA, BELLOMIO, VERÓNICA, AGÜERO, SANTIAGO, SPINDLER, WALTER, TAMBORENEA, MARÍA N., SCHIMID, MARCELA, CECCATO, FEDERICO, SALA, JOSÉ P., PAIRA, SERGIO, SPINDLER, ALBERTO, SORIANO, ENRIQUE R., PONS ESTEL, BERNARDO A., CAEIRO, FRANCISCO, ALVARELLOS, ALEJANDRO, and SAURIT, VERÓNICA

Abstract

Copyright of Medicina (Buenos Aires) is the property of Medicina (Buenos Aires) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2013

50. Systemic lupus erythematosus.

Author

BERTOLI, ANA, CALVO-ALÉN, JAIME, TOLOZA, SERGIO, URIBE, AMÉRICA, FERNANDEZ, MÓNICA, and ALARCÓN, GRACIELA

Published
2006

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