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177 results on '"Bertorelli, Giuseppina"'

5. Regular versus as-needed budesonide and formoterol combination treatment for moderate asthma: a non-inferiority, randomised, double-blind clinical trial

Author

Papi, Alberto, Marku, Brunilda, Scichilone, Nicola, Maestrelli, Piero, Paggiaro, Pierluigi, Saetta, Marina, Nava, Stefano, Folletti, Ilenia, Bertorelli, Giuseppina, Bertacco, Stefano, Contoli, Marco, Plebani, Mario, Barbaro, Maria Pia Foschino, Spanevello, Antonio, Aliani, Maria, Pannacci, Marco, Morelli, Paolo, Beghé, Bianca, and Fabbri, Leonardo M

Published
2015
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9. What happens to people’s lungs when they get coronavirus disease 2019?

Author

Frizzelli, Annalisa, Tuttolomondo, Domenico, Aiello, Marina, Majori, Maria, Bertorelli, Giuseppina, and Chetta, Alfredo

Subjects
Respiratory Distress Syndrome, Reviews/Focus on, SARS-CoV-2, viruses, Respiration, Pneumonia, Viral, virus diseases, COVID-19, Pneumonia, Respiratory failure, Betacoronavirus, Animals, Humans, ARDS, Coronavirus Infections, Lung, Pandemics
Abstract

The novel coronavirus SARS-CoV-2 was first identified in Wuhan in December 2019 as cause of the consequent novel coronavirus disease 2019 (COVID-19). The virus has since spread worldwide. The clinical presentation following human infection ranges from a mild upper respiratory tract infection to severe acute respiratory distress syndrome and sepsis. We reviewed literature using Pubmed to identify relevant English-language articles published until April 15, 2020. Search terms include novel coronavirus pneumonia, severe acute respiratory syndrome coronavirus 2, coronavirus and ventilation. We summarized what SARS-CoV-2 infection means for the lungs. (www.actabiomedica.it)

Published
2020

10. Idiopathic pulmonary fibrosis and occupational risk factors

Author

Ranzieri, Silvia, Illica Magrini, Elisa, Mozzoni, Paola, Andreoli, Roberta, Pelà, Giovanna, Bertorelli, Giuseppina, and Corradi, Massimo

Subjects
environmental factors, Risk Factors, Occupational Exposure, lung fibrosis, occupation, Humans, Original Article, Idiopathic pulmonary fibrosis, Dust, occupational factors, respiratory system, respiratory tract diseases
Abstract

Idiopathic pulmonary fibrosis (IPF) is a rare lung disease of unknown origin that rapidly leads to death. However, the rate of disease progression varies from one individual to another and is still difficult to predict. The prognosis of IPF is poor, with a median survival of three to five years after diagnosis, without curative therapies other than lung transplantation. The factors leading to disease onset and progression are not yet completely known. The current disease paradigm is that sustained alveolar epithelial micro-injury caused by environmental triggers (e.g., cigarette smoke, microaspiration of gastric content, particulate dust, viral infections or lung microbial composition) leads to alveolar damage resulting in fibrosis in genetically susceptible individuals. Numerous epidemiological studies and case reports have shown that occupational factors contribute to the risk of developing IPF. In this perspective, we briefly review the current understanding of the pathophysiology of IPF and the importance of occupational factors in the pathogenesis and prognosis of the disease. Prompt identification and elimination of occult exposure may represent a novel treatment approach in patients with IPF.

Published
2019

15. Detection of Small Airway Dysfunction in Asymptomatic Smokers with Preserved Spirometry: The Value of the Impulse Oscillometry System

Author

Pisi,Roberta, Aiello,Marina, Frizzelli,Annalisa, Calzetta,Luigino, Marchi,Laura, Bertorelli,Giuseppina, Pisi,Giovanna, Chetta,Alfredo, Pisi,Roberta, Aiello,Marina, Frizzelli,Annalisa, Calzetta,Luigino, Marchi,Laura, Bertorelli,Giuseppina, Pisi,Giovanna, and Chetta,Alfredo

Abstract

Roberta Pisi,1 Marina Aiello,1 Annalisa Frizzelli,1 Luigino Calzetta,1 Laura Marchi,1 Giuseppina Bertorelli,1 Giovanna Pisi,2 Alfredo Chetta1 1Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy; 2Department of Pediatrics, Cystic Fibrosis Center, University Hospital, Parma, ItalyCorrespondence: Luigino CalzettaDepartment of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma, Viale A. Gramsci, 14, Parma, 43126, ItalyEmail luigino.calzetta@unipr.itPurpose: Smoking-induced bronchiolitis with progressive small airway dysfunction (SAD) is a leading cause of chronic obstructive pulmonary disease. We investigated the value of using the impulse oscillometry system (IOS) to detect SAD in asymptomatic smokers with preserved spirometry.Patients and Methods: We included 75 asymptomatic smokers (37 females, mean age 47± 12 years, 26± 17 pack/year) with preserved spirometry [forced expiratory volume at 1st second (FEV1)/forced vital capacity (FVC) ≥ 0.70 and normal FVC] and 34 never-smokers (19 females, mean age 42± 15 years).Results: In smokers, pack/years were significantly related to spirometry and IOS parameters (p < 0.05). The values of the fall in resistance from 5 Hz to 20 Hz (R5 – R20) were significantly and inversely related to the values of the ratio of forced expiratory volume in 3 and in 6 seconds (FEV3/FEV6) (p < 0.05). In addition, the percentage of heavy smokers (≥ 30 pack/year) with R5 – R20 > 0.07 kPa·s·L− 1, considered as IOS index of SAD, but not with FEV3/FEV6 less than a lower limit of normal, a spirometry index of SAD, was significantly higher than that of mild smokers (< 30 pack/year) and never-smokers (p < 0.05).Conclusion: This study demonstrates that IOS has the potential to detect SAD in asymptomatic heavy smokers with preserved spirometry and with FEV3/FEV6 values in the normal range. We confirm that IOS provides parameters whi

Published
2021

17. Structured reporting for fibrosing lung disease: a model shared by radiologist and pulmonologist

Author

Sverzellati, Nicola, Odone, Anna, Silva, Mario, Polverosi, Roberta, Florio, Carlo, Cardinale, Luciano, Cortese, Giancarlo, Addonisio, Giancarlo, Zompatori, Maurizio, Dalpiaz, Giorgia, Piciucchi, Sara, Larici, Anna Rita, Agostini, Carlo, Albera, Carlo, Attinà, Domenico, Battista, Giuseppe, Bertelli, Elena, Bertorelli, Giuseppina, Bnà, Claudio, Bonifazi, Martina, Bonomo, Lorenzo, Borghesi, Andrea, Calandriello, Lucio, Caminati, Antonella, Capannelli, Diana, Cerri, Stefania, Ciccarese, Federica, Colombi, Davide, Confalonieri, Marco, Del Ciello, Annaemilia, della Casa, Giovanni, Dore, Roberto, Falaschi, Fabio, Farchione, Alessandra, Feragalli, Beatrice, Franchi, Paola, Gavelli, Giampaolo, Harari, Sergio, Luppi, Fabrizio, Maggi, Fabio, Mazzei, Maria Antonietta, Mereu, Manuela, Milanese, Gianluca, Palmucci, Stefano, Patea, Rosa Lucia, Pesci, Alberto, Piolanti, Marco, Poletti, Venerino, Rea, Gaetano, Richeldi, Luca, Rogliani, Paola, Romei, Chiara, Rottoli, Paola, Sanduzzi-Zamparelli, Alessandro, Sebastiani, Alfredo, Sergiacomi, Gianluigi, Soardi, Gian Alberto, Spaggiari, Lucia, Spagnolo, Paolo, Tomassetti, Sara, Trisolini, Rocco, Valentini, Adele, Vancheri, Carlo, Vespro, Valentina, Volterrani, Luca, Sverzellati, N, Odone, A, Silva, M, Polverosi, R, Florio, C, Cardinale, L, Cortese, G, Addonisio, G, Zompatori, M, Dalpiaz, G, Piciucchi, S, Larici, A, Agostini, C, Albera, C, Attinà, D, Battista, G, Bertelli, E, Bertorelli, G, Bnà, C, Bonifazi, M, Bonomo, L, Borghesi, A, Calandriello, L, Caminati, A, Capannelli, D, Cerri, S, Ciccarese, F, Colombi, D, Confalonieri, M, Del Ciello, A, della Casa, G, Dore, R, Falaschi, F, Farchione, A, Feragalli, B, Franchi, P, Gavelli, G, Harari, S, Luppi, F, Maggi, F, Mazzei, M, Mereu, M, Milanese, G, Palmucci, S, Patea, R, Pesci, A, Piolanti, M, Poletti, V, Rea, G, Richeldi, L, Rogliani, P, Romei, C, Rottoli, P, Sanduzzi-Zamparelli, A, Sebastiani, A, Sergiacomi, G, Soardi, G, Spaggiari, L, Spagnolo, P, Tomassetti, S, Trisolini, R, Valentini, A, Vancheri, C, Vespro, V, Volterrani, L, Sverzellati, N., Odone, A., Silva, M., Polverosi, R., Florio, C., Cardinale, L., Cortese, G., Addonisio, G., Zompatori, M., Dalpiaz, G., Piciucchi, S., Larici, A. R., Agostini, C., Albera, C., Attina, D., Battista, G., Bertelli, E., Bertorelli, G., Bna, C., Bonifazi, M., Bonomo, L., Borghesi, A., Calandriello, L., Caminati, A., Capannelli, D., Cerri, S., Ciccarese, F., Colombi, D., Confalonieri, M., Del Ciello, A., Della Casa, G., Dore, R., Falaschi, F., Farchione, A., Feragalli, B., Franchi, P., Gavelli, G., Harari, S., Luppi, F., Maggi, F., Mazzei, M. A., Mereu, M., Milanese, G., Palmucci, S., Patea, R. L., Pesci, A., Piolanti, M., Poletti, V., Rea, G., Richeldi, L., Rogliani, P., Romei, C., Rottoli, P., Sanduzzi-Zamparelli, A., Sebastiani, A., Sergiacomi, G., Soardi, G. A., Spaggiari, L., Spagnolo, P., Tomassetti, S., Trisolini, R., Valentini, A., Vancheri, C., Vespro, V., Volterrani, L., Sverzellati, Nicola, Odone, Anna, Silva, Mario, Polverosi, Roberta, Florio, Carlo, Cardinale, Luciano, Cortese, Giancarlo, Addonisio, Giancarlo, Zompatori, Maurizio, Dalpiaz, Giorgia, Piciucchi, Sara, Larici, Anna Rita, Agostini, Carlo, Albera, Carlo, Attinà, Domenico, Battista, Giuseppe, Bertelli, Elena, Bertorelli, Giuseppina, Bnà, Claudio, Bonifazi, Martina, Bonomo, Lorenzo, Borghesi, Andrea, Calandriello, Lucio, Caminati, Antonella, Capannelli, Diana, Cerri, Stefania, Ciccarese, Federica, Colombi, Davide, Confalonieri, Marco, Del Ciello, Annaemilia, della Casa, Giovanni, Dore, Roberto, Falaschi, Fabio, Farchione, Alessandra, Feragalli, Beatrice, Franchi, Paola, Gavelli, Giampaolo, Harari, Sergio, Luppi, Fabrizio, Maggi, Fabio, Mazzei, Maria Antonietta, Mereu, Manuela, Milanese, Gianluca, Palmucci, Stefano, Patea, Rosa Lucia, Pesci, Alberto, Piolanti, Marco, Poletti, Venerino, Rea, Gaetano, Richeldi, Luca, Rogliani, Paola, Romei, Chiara, Rottoli, Paola, Sanduzzi-Zamparelli, Alessandro, Sebastiani, Alfredo, Sergiacomi, Gianluigi, Soardi, Gian Alberto, Spaggiari, Lucia, Spagnolo, Paolo, Tomassetti, Sara, Trisolini, Rocco, Valentini, Adele, Vancheri, Carlo, Vespro, Valentina, and Volterrani, Luca

Subjects
Male, Research Report, Radiology, Nuclear Medicine and Imaging, Delphi Technique, Settore MED/10 - Malattie dell'Apparato Respiratorio, Pulmonary Fibrosis, Delphi method, Computed tomography, Standardized report, Consensus,High-resolution computed tomography, Lung fibrosis, Standardized report, Structured report, 030218 nuclear medicine & medical imaging, 0302 clinical medicine, Theoretical, Models, Nuclear Medicine and Imaging, Pulmonary Medicine, Prospective Studies, Tomography, Pulmonologists, High-resolution computed tomography, computer.programming_language, medicine.diagnostic_test, General Medicine, Middle Aged, X-Ray Computed, 030220 oncology & carcinogenesis, Consensus, Lung fibrosis, Structured report, Female, Radiology, Delphi round, Adult, Aged, Humans, Models, Theoretical, Tomography, X-Ray Computed, medicine.medical_specialty, Chest Radiology, education, Lung fibrosi, Consensu, 03 medical and health sciences, Settore MED/36 - Diagnostica per Immagini e Radioterapia, Structured reporting, medicine, business.industry, Pulmonologist, Lung disease, business, computer, Delphi
Abstract

Objectives To apply the Delphi exercise with iterative involvement of radiologists and pulmonologists with the aim of defining a structured reporting template for high-resolution computed tomography (HRCT) of patients with fibrosing lung disease (FLD). Methods The writing committee selected the HRCT criteria—the Delphi items—for rating from both radiology panelists (RP) and pulmonology panelists (PP). The Delphi items were first rated by RPs as “essential”, “optional”, or “not relevant”. The items rated “essential” by

Published
2017

18. Cryptogenic Fibrosing Pleuritis

Author

Manco, Alessandra Anna, additional, Alfieri, Veronica, additional, Gnetti, Letizia, additional, Aiello, Marina, additional, Bertorelli, Giuseppina, additional, Majori, Maria, additional, and Chetta, Alfredo, additional

Published
2021
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22. Comorbidities in sarcoidosis: a retrospective Italian study

Author

Aredano, Ilaria, primary, Burgazzi, Barbara, additional, Beneventi, Elena, additional, Goldoni, Matteo, additional, Alfieri, Veronica, additional, Aiello, Marina, additional, Agusta, Fabio, additional, Bertorelli, Giuseppina, additional, and Chetta, Alfredo Antonio, additional

Published
2020
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29. Pulmonary hernia: Case report and review of the literature

Author

Scelfo, Chiara, Longo, Chiara, Aiello, Marina, Bertorelli, Giuseppina, Crisafulli, Ernesto, and Chetta, Alfredo

Subjects
thoracic surgical intervention, Case Report, Case Reports, Pulmonary hernia
Abstract

Pulmonary hernia (PH) is an uncommon condition. We report a case of PH secondary to thoracic surgical intervention. In addition to the rarity, the peculiarity of the case is given by the clinical course as it is characterized by a clinical latency before the onset. The patient showed risk factors such as obesity and poliomyelitis infection sequelae. We also reviewed the literature about this topic.

Published
2018

31. Quantitative computed tomography detects interstitial lung diseases proven by biopsy

Author

Ariani, Alarico, Imperatori, Andrea, Castiglioni, Massimo, Daffrè, Elisa, Aiello, Marina, Bertorelli, Giuseppina, Chetta, Alfredo, Dominioni, Lorenzo, and Rotolo, Nicola

Subjects
body regions, Pulmonary and Respiratory Medicine, Original Article: Clinical Research, Idiopathic pulmonary fibrosis, Quantitative computed tomography, Sarcoidosis, Internal Medicine, Immunology and Allergy, respiratory system, respiratory tract diseases
Abstract

Background: The Quantitative chest CT (QCT) is emerging as a promising tool in the assessment of interstitial lung disease (ILD). However, the precise relationship between QCT parameters and the fibrosis detectable in lung tissue, remains to be established. Objectives: The aim of this study was to compare QCT and histopathological features in patients with ILD. Moreover we verified if the QCT assessment is similar in patients with or without a ILD diagnosis proven by a biopsy. Methods: Twenty patients affected by ILD who underwent a chest CT and, later, a lung biopsy, were enrolled. Patients were divided according to the histopathological findings (IPF vs sarcoidosis) in two groups (respectively bIPF and bSarc). Other 20 patients with a radiological diagnosis of IPF were included in a control group (rIPF). All CTs were post-processed with a free software (Horos) in order to obtain an ILD quantitative assessment. Results: There were no differences in terms of gender, smoking habit and spirometric values between patients’ groups. rIPF subjects were older than the other: 70 vs 59 and 47 years (p

Published
2018

35. Relationship between atopy, asthma and alpha-1 antitrypsin deficiency

Author

Aiello, Marina, primary, Fantin, Alberto, additional, Frizzelli, Annalisa, additional, Longo, Chiara, additional, Negri, Melissa, additional, Bonatti, Francesco, additional, Percesepe, Antonio, additional, Bertorelli, Giuseppina, additional, Crisafulli, Ernesto, additional, Ferrarotti, Ilaria, additional, Pisi, Roberta, additional, and Chetta, Alfredo, additional

Published
2019
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36. Overall mortality in combined pulmonary fibrosis and emphysema related to systemic sclerosis

Author

Ariani, Alarico, primary, Silva, Mario, additional, Bravi, Elena, additional, Parisi, Simone, additional, Saracco, Marta, additional, De Gennaro, Fabio, additional, Caimmi, Cristian, additional, Girelli, Francesco, additional, De Santis, Maria, additional, Volpe, Alessandro, additional, Lumetti, Federica, additional, Hax, Vanessa, additional, Bredemeier, Markus, additional, Alfieri, Veronica, additional, Santilli, Daniele, additional, Bodini, Flavio Cesare, additional, Lucchini, Gianluca, additional, Mozzani, Flavio, additional, Seletti, Valeria, additional, Bacchini, Emanuele, additional, Arrigoni, Eugenio, additional, Giuggioli, Dilia, additional, Chakr, Rafael, additional, Idolazzi, Luca, additional, Bertorelli, Giuseppina, additional, Imberti, Davide, additional, Michieletti, Emanuele, additional, Paolazzi, Giuseppe, additional, Fusaro, Enrico, additional, Chetta, Alfredo Antonio, additional, Scirè, Carlo Alberto, additional, and Sverzellati, Nicola, additional

Published
2019
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38. Structured reporting for fibrosing lung disease: a model shared by radiologist and pulmonologist

Author

Sverzellati, N, Odone, A, Silva, M, Polverosi, R, Florio, C, Cardinale, L, Cortese, G, Addonisio, G, Zompatori, M, Dalpiaz, G, Piciucchi, S, Larici, A, Agostini, C, Albera, C, Attinà, D, Battista, G, Bertelli, E, Bertorelli, G, Bnà, C, Bonifazi, M, Bonomo, L, Borghesi, A, Calandriello, L, Caminati, A, Capannelli, D, Cerri, S, Ciccarese, F, Colombi, D, Confalonieri, M, Del Ciello, A, della Casa, G, Dore, R, Falaschi, F, Farchione, A, Feragalli, B, Franchi, P, Gavelli, G, Harari, S, Luppi, F, Maggi, F, Mazzei, M, Mereu, M, Milanese, G, Palmucci, S, Patea, R, Pesci, A, Piolanti, M, Poletti, V, Rea, G, Richeldi, L, Rogliani, P, Romei, C, Rottoli, P, Sanduzzi-Zamparelli, A, Sebastiani, A, Sergiacomi, G, Soardi, G, Spaggiari, L, Spagnolo, P, Tomassetti, S, Trisolini, R, Valentini, A, Vancheri, C, Vespro, V, Volterrani, L, Sverzellati, Nicola, Odone, Anna, Silva, Mario, Polverosi, Roberta, Florio, Carlo, Cardinale, Luciano, Cortese, Giancarlo, Addonisio, Giancarlo, Zompatori, Maurizio, Dalpiaz, Giorgia, Piciucchi, Sara, Larici, Anna Rita, Agostini, Carlo, Albera, Carlo, Attinà, Domenico, Battista, Giuseppe, Bertelli, Elena, Bertorelli, Giuseppina, Bnà, Claudio, Bonifazi, Martina, Bonomo, Lorenzo, Borghesi, Andrea, Calandriello, Lucio, Caminati, Antonella, Capannelli, Diana, Cerri, Stefania, Ciccarese, Federica, Colombi, Davide, Confalonieri, Marco, Del Ciello, Annaemilia, della Casa, Giovanni, Dore, Roberto, Falaschi, Fabio, Farchione, Alessandra, Feragalli, Beatrice, Franchi, Paola, Gavelli, Giampaolo, Harari, Sergio, Luppi, Fabrizio, Maggi, Fabio, Mazzei, Maria Antonietta, Mereu, Manuela, Milanese, Gianluca, Palmucci, Stefano, Patea, Rosa Lucia, Pesci, Alberto, Piolanti, Marco, Poletti, Venerino, Rea, Gaetano, Richeldi, Luca, Rogliani, Paola, Romei, Chiara, Rottoli, Paola, Sanduzzi-Zamparelli, Alessandro, Sebastiani, Alfredo, Sergiacomi, Gianluigi, Soardi, Gian Alberto, Spaggiari, Lucia, Spagnolo, Paolo, Tomassetti, Sara, Trisolini, Rocco, Valentini, Adele, Vancheri, Carlo, Vespro, Valentina, Volterrani, Luca, Sverzellati, N, Odone, A, Silva, M, Polverosi, R, Florio, C, Cardinale, L, Cortese, G, Addonisio, G, Zompatori, M, Dalpiaz, G, Piciucchi, S, Larici, A, Agostini, C, Albera, C, Attinà, D, Battista, G, Bertelli, E, Bertorelli, G, Bnà, C, Bonifazi, M, Bonomo, L, Borghesi, A, Calandriello, L, Caminati, A, Capannelli, D, Cerri, S, Ciccarese, F, Colombi, D, Confalonieri, M, Del Ciello, A, della Casa, G, Dore, R, Falaschi, F, Farchione, A, Feragalli, B, Franchi, P, Gavelli, G, Harari, S, Luppi, F, Maggi, F, Mazzei, M, Mereu, M, Milanese, G, Palmucci, S, Patea, R, Pesci, A, Piolanti, M, Poletti, V, Rea, G, Richeldi, L, Rogliani, P, Romei, C, Rottoli, P, Sanduzzi-Zamparelli, A, Sebastiani, A, Sergiacomi, G, Soardi, G, Spaggiari, L, Spagnolo, P, Tomassetti, S, Trisolini, R, Valentini, A, Vancheri, C, Vespro, V, Volterrani, L, Sverzellati, Nicola, Odone, Anna, Silva, Mario, Polverosi, Roberta, Florio, Carlo, Cardinale, Luciano, Cortese, Giancarlo, Addonisio, Giancarlo, Zompatori, Maurizio, Dalpiaz, Giorgia, Piciucchi, Sara, Larici, Anna Rita, Agostini, Carlo, Albera, Carlo, Attinà, Domenico, Battista, Giuseppe, Bertelli, Elena, Bertorelli, Giuseppina, Bnà, Claudio, Bonifazi, Martina, Bonomo, Lorenzo, Borghesi, Andrea, Calandriello, Lucio, Caminati, Antonella, Capannelli, Diana, Cerri, Stefania, Ciccarese, Federica, Colombi, Davide, Confalonieri, Marco, Del Ciello, Annaemilia, della Casa, Giovanni, Dore, Roberto, Falaschi, Fabio, Farchione, Alessandra, Feragalli, Beatrice, Franchi, Paola, Gavelli, Giampaolo, Harari, Sergio, Luppi, Fabrizio, Maggi, Fabio, Mazzei, Maria Antonietta, Mereu, Manuela, Milanese, Gianluca, Palmucci, Stefano, Patea, Rosa Lucia, Pesci, Alberto, Piolanti, Marco, Poletti, Venerino, Rea, Gaetano, Richeldi, Luca, Rogliani, Paola, Romei, Chiara, Rottoli, Paola, Sanduzzi-Zamparelli, Alessandro, Sebastiani, Alfredo, Sergiacomi, Gianluigi, Soardi, Gian Alberto, Spaggiari, Lucia, Spagnolo, Paolo, Tomassetti, Sara, Trisolini, Rocco, Valentini, Adele, Vancheri, Carlo, Vespro, Valentina, and Volterrani, Luca

Abstract

Objectives: To apply the Delphi exercise with iterative involvement of radiologists and pulmonologists with the aim of defining a structured reporting template for high-resolution computed tomography (HRCT) of patients with fibrosing lung disease (FLD). Methods: The writing committee selected the HRCT criteria—the Delphi items—for rating from both radiology panelists (RP) and pulmonology panelists (PP). The Delphi items were first rated by RPs as “essential”, “optional”, or “not relevant”. The items rated “essential” by < 80% of the RP were selected for the PP rating. The format of reporting was rated by both RP and PP. Results: A total of 42 RPs and 12 PPs participated to the survey. In both Delphi round 1 and 2, 10/27 (37.7%) items were rated “essential” by more than 80% of RP. The remaining 17/27 (63.3%) items were rated by the PP in round 3, with 2/17 items (11.7%) rated “essential” by the PP. PP proposed additional items for conclusion domain, which were rated by RPs in the fourth round. Poor consensus was observed for the format of reporting. Conclusions: This study provides a template for structured report of FLD that features essential items as agreed by expert thoracic radiologists and pulmonologists

Published
2018

40. Mast cell and histamine involvement in farmer's lung disease

Author

Miadonna, Antonio, Pesci, Alberto, Tedeschi, Alberto, Bertorelli, Giuseppina, Arquati, Massimo, and Olivieri, Dario

Subjects
Histamine -- Physiological aspects, Lung diseases, Interstitial -- Diagnosis, Mast cells -- Physiological aspects, Health, Diagnosis, Physiological aspects
Abstract

The aim of this study was to evaluate the cellular and biochemical characteristics of the bronchoalveolar lavage (BAL) fluid in patients with farmer's lung disease (FLD). Total cell numbers in [...]

Published
1994

41. Mast cells in fibrotic lung disorders

Author

Pesci, Alberto, Bertorelli, Giuseppina, Gabrielli, Marzio, and Olivieri, Dario

Subjects
Pulmonary fibrosis -- Development and progression, Mast cells -- Physiological aspects, Health, Physiological aspects, Development and progression
Abstract

Fibrotic lung disorders are chronic inflammatory diseases in which inflammatory processes in the lower respiratory tract injure the lung and modulate the proliferation of mesenchymal cells that form the basis [...]

Published
1993

42. Lung function and bronchial responsiveness after bronchoalveolar lavage and bronchial biopsy performed without premedication in stable asthmatic subjects

Author

Chetta, Alfredo, Foresi, Antonio, Bertorelli, Giuseppina, Pesci, Alberto, and Olivieri, Dario

Subjects
Bronchoalveolar lavage -- Usage -- Physiological aspects, Lungs -- Physiological aspects -- Usage, Asthma -- Care and treatment, Health, Care and treatment, Physiological aspects, Usage
Abstract

We evaluated tolerance, safety, and effects on lung function and bronchial responsiveness of BAL (4 x 50 ml) combined with BB (three to five specimens) performed without premedication in 13 [...]

Published
1992

43. Inflammatory markers in bronchoalveolar lavage and in bronchial biopsy in asthma during remission

Author

Foresi, Antonio, Bertorelli, Giuseppina, Pesci, Alberto, Chetta, Alfredo, and Olivieri, Dario

Subjects
Bronchi -- Physiological aspects, Lungs -- Biopsy, Bronchoalveolar lavage -- Physiological aspects, Leukocytes -- Physiological aspects, Asthma -- Physiological aspects, Health, Physiological aspects
Abstract

Bronchoalveolar lavage and BB were performed in 13 asthmatic and six healthy subjects to characterize cellular markers of inflammation in BAL and BB; to compare cellular profile of BAL with [...]

Published
1990

44. Clinical manifestations in patients with PI*MMMalton genotypes. A matter still unsolved in alpha‐1 antitrypsin deficiency.

Author

Aiello, Marina, Fantin, Alberto, Longo, Chiara, Ferrarotti, Ilaria, Bertorelli, Giuseppina, and Chetta, Alfredo

Subjects
GENOTYPES, ABDOMINAL aortic aneurysms, AORTIC aneurysms, LUNG diseases, DISEASE prevalence
Abstract

We report the genetic variants associated with alpha‐1 antitrypsin deficiency (AATD) in 117 patients admitted to our outpatient clinic and characterized by a serum concentration of AAT lower than 113 mg/dL. We focused on the M‐like heterozygous variant of the SERPINA1 gene called PI*MMMalton, and describe three patients with this variant. While the role of homozygous AATD in liver and pulmonary disease is well established, the association between heterozygous AATD and chronic liver and pulmonary disease is still under investigation. The PI*MMMalton genotype was found in 5.8% of patients with a pathological genotype of AATD and in 14.3% of the subjects when considering only those with intermediate AATD. There were no liver or renal abnormalities in patients with the PI*MMMalton genotype. The PI*MMMalton patients included here showed a normal liver function, and none had renal function abnormalities or abdominal aortic aneurysm. Only a prevalence of lung disease was detected. [ABSTRACT FROM AUTHOR]

Published
2020
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46. In adults with cystic fibrosis (CF), the high-resolution computed tomography (HRCT) predicts maximal exercise capacity

Author

Crisafulli, Ernesto, primary, Teopompi, Elisabetta, additional, Luceri, Silvia, additional, Longo, Francesco, additional, Pagano, Paolo, additional, Longo, Chiara, additional, Ielpo, Antonella, additional, Aiello, Marina, additional, Bertorelli, Giuseppina, additional, Sverzellati, Nicola, additional, Chetta, Alfredo, additional, and Pisi, Giovanna, additional

Published
2018
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48. Heart rate recovery is associated with ventilatory constraints and excess ventilation during exercise in patients with chronic obstructive pulmonary disease

Author

Crisafulli, Ernesto, primary, Vigna, Matteo, additional, Ielpo, Antonella, additional, Tzani, Panagiota, additional, Mangia, Angelo, additional, Teopompi, Elisabetta, additional, Aiello, Marina, additional, Alfieri, Veronica, additional, Bertorelli, Giuseppina, additional, Palange, Paolo, additional, and Chetta, Alfredo, additional

Published
2018
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49. Trattamento personalizzato dei pazienti con BPCO in fase stabile

Author

Caramori, Gaetano, Casolari, Paolo, Carone, Mauro, Bertorelli, Giuseppina, Banfi, Paolo, and Andò, Filippo

Subjects
Anticolinergici, Beta2 agonisti, BPCO, Glucocorticoidi, Anticolinergici, Beta2 agonisti, Roflumilast, Fumo di tabacco, BPCO, Glucocorticoidi, Socio-culturale, Fumo di tabacco, Roflumilast
Published
2016

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