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3 results on '"Besma MBarek"'

1. Sentinel Lymph Node Biopsy in Cutaneous Squamous Cell Carcinoma Series of 37 Cases and Systematic Review of the Literature

Author

Raphael Lhote, Jérôme Lambert, Julie Lejeune, Jeremy Gottlieb, Antoine Badaoui, Maxime Battistella, Jennifer Roux, Cecile Pages, Laetitia Vercellino, Catherine Vilmer, Christine Le Maignan, Catherine Escande, Besma MBarek, Martine Bagot, Celeste Lebbé, and Nicole Basset-Seguin

Subjects
squamouscellcarcinoma, sentinellymphnode, overallsurvival, relapsefreesurvival, Dermatology, RL1-803
Abstract

Cutaneous squamous cell carcinoma (cSSC) is one of the most common skin cancers and can lead to patient death. Early detection of node metastasis is a major goal for dermatologists and oncologists. The procedure sentinel lymph node biopsy has been proposed to improve early detection of node metastasis. The aim of this study was to evaluate the efficacy and impact of this technique on the prognosis of cSSC. A total of 37 patients (Saint Louis Hospital, Paris, France) who had undergone sentinel lymph node biopsy and 290 cases from the literature were analysed. The mean rate of positive sentinel lymph node biopsy was 0.14 [95% CI 0.09–0.22]. However, relapse-free survival and overall survival were not affected by sentinel lymph node status (log-rank test; p = 0.08 and p = 0.31, respectively), suggesting that this procedure is not mandatory in the management of cSSC.

Published
2018
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2. Sentinel Lymph Node Biopsy in Cutaneous Squamous Cell Carcinoma Series of 37 Cases and Systematic Review of the Literature

Author

Nicole Basset-Seguin, J. Gottlieb, Martine Bagot, Laetitia Vercellino, Catherine Escande, Julie Lejeune, Cécile Pagès, Besma MBarek, Maxime Battistella, Céleste Lebbé, R. Lhote, C. Vilmer, J. Roux, Christine Le Maignan, Jérôme Lambert, and Antoine Badaoui

Subjects
Male, Paris, medicine.medical_specialty, Skin Neoplasms, Time Factors, Cutaneous squamous cell carcinoma, Node metastasis, Sentinel lymph node, Early detection, Kaplan-Meier Estimate, Dermatology, Disease-Free Survival, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Risk Factors, overallsurvival, Biopsy, Overall survival, sentinellymphnode, Humans, Medicine, Early Detection of Cancer, Aged, Neoplasm Staging, Proportional Hazards Models, Retrospective Studies, medicine.diagnostic_test, Sentinel Lymph Node Biopsy, business.industry, relapsefreesurvival, General Medicine, Middle Aged, Treatment Outcome, Lymphatic Metastasis, 030220 oncology & carcinogenesis, RL1-803, Carcinoma, Squamous Cell, Disease Progression, Female, Lymph Nodes, Radiology, squamouscellcarcinoma, business
Abstract

Cutaneous squamous cell carcinoma (cSSC) is one of the most common skin cancers and can lead to patient death. Early detection of node metastasis is a major goal for dermatologists and oncologists. The procedure sentinel lymph node biopsy has been proposed to improve early detection of node metastasis. The aim of this study was to evaluate the efficacy and impact of this technique on the prognosis of cSSC. A total of 37 patients (Saint Louis Hospital, Paris, France) who had undergone sentinel lymph node biopsy and 290 cases from the literature were analysed. The mean rate of positive sentinel lymph node biopsy was 0.14 [95% CI 0.09-0.22]. However, relapse-free survival and overall survival were not affected by sentinel lymph node status (log-rank test; p = 0.08 and p = 0.31, respectively), suggesting that this procedure is not mandatory in the management of cSSC.

Published
2018

3. Impact on treatment adherence, side effects control, patients QoL, and rehospitalization rate through new management of oral chemotherapy

Author

Jocelyne Imbeau, Carole Miette, Laurence Bisseux, Amine Cherait, Thierry Collon, Ida Pavese, Ida Iurisci, Besma MBarek, and Yasmine Chait

Subjects
Cancer Research, medicine.medical_specialty, education.field_of_study, Oral chemotherapy, business.industry, Treatment adherence, Population, humanities, Oncology, Internal medicine, Medicine, Suburban area, business, education
Abstract

e18533Background: In our oncology department, serving an under-privileged suburban area north-east of Paris, the patient’s population treated with oral chemotherapy increased steadily during the la...

Published
2018
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