30 results on '"Betadine Solution"'
Search Results
2. Preoperative Preparation, Postoperative Care, and Complication Management
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Hong, Jun Hyuk, Park, Nam Cheol, editor, Kim, Sae Woong, editor, and Moon, Du Geon, editor
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- 2016
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3. Chronic In Vivo Microcirculatory and Hemodynamic Techniques
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Hutchins, Phillip M., Lynch, Colleen D., Maultsby, Janie, Bevan, John A., editor, Halpern, William, editor, and Mulvany, Michael J., editor
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- 1991
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4. The influence of palatal harvesting technique on the donor site vascular injury: A split‐mouth comparative cadaver study
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David W. Brzezinski, Sharon S Namazi, Hom-Lay Wang, Lorenzo Tavelli, Theodora E. Danciu, Hsun-Liang Chan, and Shayan Barootchi
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0301 basic medicine ,Palate ,business.industry ,Oral Surgical Procedures ,External carotid artery ,Betadine Solution ,Histology ,030206 dentistry ,Vascular System Injuries ,Soft tissue graft ,03 medical and health sciences ,Free gingival graft ,030104 developmental biology ,0302 clinical medicine ,Blood loss ,Collagen sponge ,Cadaver ,medicine.artery ,medicine ,Humans ,Periodontics ,Collagen ,Nuclear medicine ,business - Abstract
BACKGROUND The aim of this study was to evaluate the influence of two harvesting approaches on the donor site vascular injury. METHODS A split-mouth cadaver study was designed on 21 fresh donor heads. Every hemi-palate was assigned to receive the trap-door harvesting technique (TDT) or the epithelialized free gingival graft harvesting technique (FGGT). A soft tissue graft was harvested from each side for histology analyses. Betadine solution was used to inject the external carotid artery and a collagen sponge was positioned over the harvested area to compare the amount of "leakage." RESULTS The mean leakage observed was 16.56 ± 3.01 µL in the FGGT-harvested sites, and 69.21 ± 7.08 µL for the TDT group, a ratio of 4.18 (P
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- 2019
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5. Reducing Surgical Site Infection in Spinal Surgery With Betadine Irrigation and Intrawound Vancomycin Powder.
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Tomov, Marko, Mitsunaga, Lance, Durbin-Johnson, Blythe, Nallur, Deepak, and Roberto, Rolando
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SPINAL surgery , *SURGICAL site , *POVIDONE-iodine , *VANCOMYCIN , *PREOPERATIVE risk factors , *BACTERIOLOGY , *SURGICAL complications , *THERAPEUTICS ,PREVENTION of surgical complications - Abstract
Study Design. Retrospective analysis. Objective. The objective of this study was to evaluate the efficacy of a surgical site infection (SSI) prevention protocol instituted in the Orthopaedic Spine Department at our institution. Summary of Background Data. SSI is an undesired complication of orthopedic spine surgical procedures. It poses a significant risk to the patient, as well as a financial toll on the health care system. A wide range of prophylactic measures have been used to attempt to reduce SSI rates. Methods. A protocol consisting of a combination of 0.3% Betadine wound irrigation and 1 g of intrawound Vancomycin powder application was developed at our institution. Multiple data sources were consolidated for thorough evaluation of changes in SSI rates, patient risk factors, and changes in bacteriology. Identification of risk factors that predispose patients to SSI was performed using mixed-effects logistic regression in a univariate fashion. Risk factors with P values of 0.05 or less in univariate analysis were included together in a multivariate mixed-effects logistic regression model. Results. SSI rates were reduced by 50% after the intervention; x 2 analysis comparing the SSI rates between the pre- and postintervention periods yielded a P value of 0.042. Rates of methicillin-resistant Staphylococcus aureus dropped from 30% to 7% and the rates of multibacterial infections dropped from 37% to 27%. The risk factors that were statistically significant in multivariate analysis were the following: age (odds ratio [OR] = 0.93), anemia (OR = 30.73), prior operation (OR = 27.45), and vertebral fracture (OR = 22.22). Conclusion. The combination of Betadine wound irrigation and intrawound vancomycin powder application led to both a clinically and statistically significant decrease in SSI rates by 50%. Bacteriology analysis and risk factor assessment proved to be valuable tools in assessing the efficacy of a new prophylactic measure and in the planning of future protocols. [ABSTRACT FROM AUTHOR]
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- 2015
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6. Pagetoid reticulosis (epitheliotropic cutaneous T-cell lymphoma) in an adult alpaca (Vicugna pacos)
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Andrea E. Hasbach and Adam W. Stern
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medicine.medical_specialty ,Pathology ,Skin Neoplasms ,040301 veterinary sciences ,Pagetoid reticulosis ,Betadine Solution ,Ventral abdomen ,Vicugna pacos ,Immunophenotyping ,0403 veterinary science ,Pagetoid Reticulosis ,biology.domesticated_animal ,medicine ,Animals ,General Veterinary ,biology ,business.industry ,Cutaneous T-cell lymphoma ,0402 animal and dairy science ,04 agricultural and veterinary sciences ,medicine.disease ,040201 dairy & animal science ,Lymphoma ,Immunohistochemistry ,Female ,Histopathology ,business ,Camelids, New World - Abstract
A 9-year-old, intact female alpaca ( Vicugna pacos) was presented for a second opinion with a 1-year history of nonpruritic, multifocal scaling and crusted cutaneous lesions, mainly involving skin on the face, axillae, and ventral abdomen. Clinical abnormalities were limited to the skin, and the alpaca was otherwise healthy. The initial veterinarian had examined the alpaca, found no evidence of ectoparasites with laboratory testing, and had tried several trial therapies including oral antibiotics, ivermectin, and topical use of betadine solution. At the time of presentation, the lesions had neither improved nor worsened with any attempted therapy, and multiple skin biopsies were collected. Histopathology and immunohistochemical staining findings were consistent with the pagetoid reticulosis type of cutaneous epitheliotropic T-cell lymphoma. Our report describes the clinical, histopathologic, and immunophenotypic features of pagetoid reticulosis epitheliotropic cutaneous T-cell lymphoma in an alpaca.
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- 2016
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7. The Effects of Alpha® Ointment (Containing Natural Henna) and Betadine® Solution on Episiotomy Healing in Primiparous Women: A Randomized Controlled Trial
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Zohreh Mahmoodi, Mahrokh Dolatian, Peimaneh Naghdi Dorbati, A Mahmoodi, and Katayoun Salehi
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Episiotomy ,medicine.medical_specialty ,030504 nursing ,business.industry ,medicine.medical_treatment ,Significant difference ,Betadine Solution ,General Medicine ,law.invention ,Surgery ,Clinical trial ,Red Crescent ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,Sitz bath ,Medicine ,030212 general & internal medicine ,Medical journal ,0305 other medical science ,business - Abstract
Background: Episiotomy is one of the most common surgical procedures in obstetrics performed in the second stage of labor. Objectives: This study was conducted to compare the effects of Alpha® Ointment in comparison with Betadine® solution on episiotomy healing process. Methods: The present single-blind clinical trial was conducted on 128 eligible women admitted to a university affiliated hospital in Karaj, Iran, in 2015. The subjects were divided into a case group (getting an Alpha® Ointment plus a sitz bath with Betadine® solution) and a control group (getting a sitz bath with Betadine® solution). After delivery, the mothers applied 2 g of Alpha® Ointment on their episiotomy site three times a day. The REEDA scale was used to assess the wound healing process, and the intensity of pain was assessed by measuring pain in the first 24 hours as well as the third and seventh day after delivery. Results: In the first 24 hours after delivery, the two groups were not significantly different in terms of their repair score (P = 0.27), however, the mean REEDA score was 0.25 ± 0.53 on the third day and 0.203 ± 0.47 on the seventh day in the case group, while in the control group, it was 1.32 ± 1.4 and 0.92 ± 1.17, suggesting a significant difference between the groups (P < 0.001). Conclusions: Alpha® Ointment is more effective than Betadine® solution for episiotomy wound healing and pain reduction and can, therefore, be regarded as an appropriate medication for episiotomy wound healing. © 2018, Iranian Red Crescent Medical Journal.
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- 2018
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8. Bleeding reduction after topical application of tranexamic acid together with Betadine solution in total knee arthroplasty. A randomised controlled study
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M.L.A. Tavares de Souza, Lúcio Honório de Carvalho, M.J. Gonçalves, L. Paiva Costa, L.F. Machado Soares, and E. Frois Temponi
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Male ,Tranexamic acid ,medicine.medical_specialty ,Administration, Topical ,Povidone-iodine solution ,Total knee arthroplasty ,Betadine Solution ,Postoperative Hemorrhage ,Knee Joint ,Group B ,law.invention ,Randomized controlled trial ,Blood loss ,law ,medicine ,Humans ,Orthopedics and Sports Medicine ,Prospective Studies ,Arthroplasty, Replacement, Knee ,Povidone-Iodine ,Aged ,Dose-Response Relationship, Drug ,business.industry ,Antifibrinolytic Agents ,Surgery ,Anesthesia ,Anti-Infective Agents, Local ,Drug Therapy, Combination ,Female ,Complication ,business ,Follow-Up Studies ,medicine.drug - Abstract
Introduction Topical application of tranexamic acid to the knee joint before closure in total knee arthroplasty reduces postoperative bleeding without increase in complication. However, it is unknown the effectiveness of topic TXA performed with other topical medications, like povidone-iodine solution. Materials and methods One hundred and twenty-five patients were randomized to receive 100 mL of povidone-iodine solution (control: group A) or 1.5 (group B) and 3.0 g (group C) of topical TXA in povidone-iodine solution applied into the knee before closure in total knee arthroplasty. Results The patients in the TXA groups had higher mean postoperative hemoglobin levels ( P = 0.01 and P = 0.03 in groups B and C, respectively) and a reduced postoperative blood loss in the TXA groups ( P = 0.07 and P = 0.09 in groups B and C, respectively). No significant complications were observed. Discussion In this study, topical application of tranexamic acid after total knee arthroplasty together with povidone-iodine solution results in higher postoperative hemoglobin levels and lower blood loss compared with those in the control group without other complications. Level of evidence I – I: high-powered prospective randomized trial.
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- 2015
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9. Comparing sterile bag rubbing and paint on technique in skin preparation of the hands
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Raminder S. Dhillon, Justin Chou, and Anwar Choudhary
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Alternative methods ,medicine.medical_specialty ,business.industry ,Betadine Solution ,Hand surgery ,General Medicine ,Standard technique ,Rubbing ,Surgery ,Surgical site ,Medicine ,business ,Skin preparation ,Plastic bag - Abstract
Background: The aim of this study was to compare two techniques for surgical site skin preparation in hand surgery. Methods: We compared the standard sponge paint technique versus a plastic bag immersion technique using a 10% povidone–iodine with alcohol solution (Betadine, ORION Laboratories Pty Ltd, Balcatta, WA, Australia) to prepare surgical site skin for hand surgery. This sterile bag rubbing technique involves using a sterile plastic bag filled with 60 mL of Betadine solution to immerse the subjects' hand. Samples were taken from 10 subjects for bacteria colony-forming unit (CFU) counts before and 3 min after surgical site preparation in each group. Outcome measures were preparation time and CFU reduction with a plate impression test using commercially available agar slides. Results: The sterile bag rubbing technique significantly reduced (P < 0.0001) the time required for surgical site skin preparation (28 s) compared with the standard technique (86 s). Both techniques were found to have similar efficacy in the reduction of CFU. Conclusions: The sterile bag rubbing technique is a quicker alternative method for surgical site preparation in hand surgery and has comparable efficacy to the widely practised standard paint-on technique.
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- 2010
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10. New opportunities for local therapy of pustular skin diseases
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R M Nurullin, R M Abdrakhmanov, and R R Khaliullin
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medicine.medical_specialty ,Exacerbation ,business.industry ,International Nonproprietary Name ,Pyoderma ,Betadine Solution ,Folliculitis ,General Medicine ,medicine.disease ,Dermatology ,Discontinuation ,Surgery ,Tolerability ,medicine ,Clinical efficacy ,business - Abstract
Aim. To study the effectiveness of a universal antiseptic Betadine (international nonproprietary name - povidone-iodine) in the treatment of pustular skin diseases. Methods. The study had the form of an open, non-comparative one, which involved 25 patients aged from 2.5 to 40 years (mean age 16.1±1.2 years) with disease duration from 1 to 7 days (mean 4.2±0.8) with various forms of pyoderma: 21 patients with streptococcal impetigo and 4 patients with folliculitis. Assessment of safety of the study was carried out on the basis of clinical and laboratory data, patient tolerability of the substance, the expert-opinion of the physician-researcher. Changes in the quality of life as a result of treatment of patients with pyoderma using Betadine solution was evaluated by a questionnaire SKINDEKS-29. Results. All patients willing used the proposed betadine solution. No reasons for discontinuation of treatment during the study (including side effects, allergic reactions or exacerbation of the cutaneous process) were identified. Deterioration of the quality of life on the «Emotions» scale of SKINDEKS-29 questionnaire at the beginning of treatment was 49.8±1.3 points («sometimes»), during the second visit - 26.8±0.9 points («rarely»), by the end of treatment (third visit) - 10.2±0.3 points («no»); on a scale of «Function» at the beginning of treatment - 77.8±1.8 («often»), during the second visit - 53.2±1.6 («sometimes»), by the end of treatment - 16.2±0.8 points («no»); on a scale of «Symptoms» at the beginning of treatment - 51.2±1.3 («sometimes»), during the second visit - 27.6±2.8 («rarely»), by the end of treatment - 12.3±0.3 points («no»). Conclusion. Betadine is characterized by high clinical efficacy in pustular skin diseases, good tolerance, absence of adverse reactions, a positive impact on the quality of life and can be recommended as a therapeutic and prophylactic agent.
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- 2012
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11. Transit Fixatives: An Innovative Study
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Ravi Prakash A, Shyam Ndvn, Sreenath G, Sonia Bai Jk, and Rajanikanth M
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food.ingredient ,business.industry ,transporting media ,lcsh:R ,Clinical Biochemistry ,Coconut oil ,lcsh:Medicine ,food and beverages ,Betadine Solution ,General Medicine ,Bioinformatics ,Pulp and paper industry ,Dentistry Section ,food.food ,formalin ,Rose water ,food ,Fresh Tissue ,Medicine ,biopsy ,business ,Fixative ,Fixation (histology) - Abstract
Background: Universally accepted fixative is 10% formalin which has been used for preserving the tissues and their architecture. In certain conditions, formalin might not be readily available for immediate fixation. We here by explore more economical, ecofriendly and easily available solutions that can be used as transit media/ transporting media for tissue specimens. Materials and Methods: The study included commonly available solutions like Spirit, Saline, Betadine solution, Hydrogen peroxide (H 2 O 2 ), Local anesthesia (L.A), Rose water, Coconut oil, Coconut water, Ice cold water, Honey and Milk while keeping formalin as control. The fresh tissue sample was cut into multiple bits and placed in different containers for a period of 8 hours before transferring to formalin solution. Conclusion: Transit fixatives are very important in certain situa tions where formalin is not readily available. These fixatives can be used to fix the tissues for a period of at least 8 hours without causing any damage or distortion before they are fixed in formalin solution.
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- 2015
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12. Complications of Mastopexy and Breast Reduction
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Toma T. Mugea, Andrei Miron Martin, and Laura Maria Curic
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medicine.medical_specialty ,integumentary system ,business.industry ,medicine.medical_treatment ,Mastopexy ,Betadine Solution ,medicine.disease ,Surgery ,Venous stasis ,Dermal cyst ,medicine ,Breast reduction ,Nipple areolar complex ,skin and connective tissue diseases ,Wound healing ,business - Abstract
The author discusses what a surgeon must do before performing any surgical procedure, how to avoid complications in breast reduction/mastopexy and what wound healing depends on.
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- 2014
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13. Betadine Decontamination of Donor Globes
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Elizabeth A. Mindrup, Donald J. Doughman, and Polly A. Dubbel
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Microbiological Techniques ,medicine.medical_specialty ,medicine.drug_class ,Aerobic bacteria ,Antibiotics ,Betadine Solution ,Eye ,medicine.disease_cause ,Eye Infections, Bacterial ,Corneal Transplantation ,Endophthalmitis ,medicine ,Humans ,Povidone-Iodine ,Bacteria ,business.industry ,Fungi ,Eye bank ,Human decontamination ,medicine.disease ,eye diseases ,Surgery ,Ophthalmology ,Gentamicin ,sense organs ,business ,Eye Infections, Fungal ,Staphylococcus ,medicine.drug - Abstract
Between May 1983 and December 1989, 2,921 donor eyes received by the Minnesota Lions Eye Bank underwent a decontamination protocol using 10% Betadine (1% povidone- iodine) solution. Positive pretreatment limbal cultures were obtained on 52.1% of donor eyes. Posttreatment limbal cultures demonstrated a 76.1% reduction in microbial growth, including an 85.7% reduction in Candida species. Streptococcus species were reduced by 76.7% and coagulase-negative Staphylococcus were reduced by 76.1%. In addition, of 250 donor rims obtained at the time of surgery, two had coagulase-negative. Staphylococcus present that were also present after the decontamination procedure. In no cases did endophthalmitis occur during this study. This study demonstrates that this protocol using 10% Betadine solution is extremely effective in decontaminating donor globes of aerobic bacteria and fungi. However, gentamicin-resistant organisms survived this protocol, emphasizing the need to develop storage media containing a broader-spectrum antibiotic agent than gentamicin.
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- 1993
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14. Non-infected central venous catheters in hemodialysis patients are not associated with inflammation
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Guillaume Jean, Charles Chazot, and Thierry Vanel
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medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Incidence (epidemiology) ,Betadine Solution ,Inflammation ,medicine.disease ,Gastroenterology ,Surgery ,Heparin lock ,Catheter ,Nephrology ,Bacteremia ,Internal medicine ,medicine ,cardiovascular diseases ,Hemodialysis ,medicine.symptom ,business ,Dialysis - Abstract
To the Editor: A recent study, conducted by Goldstein et al., showed that the serum C-reactive protein (CRP) level of patients who underwent hemodialysis (HD) with non-infected central venous catheters (CVCs) was higher than that of those who underwent HD via native arteriovenous fistulas (AVFs). In these patients, betadine solution was used for exit-site care.1 Our aim was to evaluate the changes in the serum CRP levels of HD patients who underwent dialysis via native AVF (AVF-1), then via temporary tunneled CVC for AVF dysfunction, and again via AVF (AVF-2). Eighteen tunneled jugular CVCs in 18 HD patients were included. Heparin lock and alcoholic-chlorhexidine solution was used for exit-site disinfection. The mean CRP values during the three periods were not different (Figure 1). A cross-sectional study in 225 HD patients in December 2008 showed that the median serum CRP levels of patients using AVF (89%) and CVC (11%) were 7 (IQR 3–20) and 10 (3–21) mg/l, respectively (NS). We have previously shown that the incidence of catheter-related bacteremia decreased from 1.1 to 0.2/1000 catheter day during 1994–1997 and 2004–2007 when betadine was substituted with alcohol-chlorhexidine solution.2 As this solution was more efficient than betadine in our hands, we hypothesized that the difference in the findings reported in the two studies may be attributed to the differences in the solution used. However, to confirm this hypothesis, a controlled study should be conducted in order to compare these two protocols.
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- 2010
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15. A comparison of chlorhexidine and povidone-iodine skin preparation for surgical operations
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Narayan Deshmukh, David A Kostyal, and Samira Y Khera
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medicine.medical_specialty ,integumentary system ,business.industry ,Chlorhexidine ,Betadine Solution ,chemistry.chemical_element ,Membrane filter ,Iodine ,Bacterial counts ,Surgery ,chemistry ,Adsorption method ,medicine ,Purdue Frederick ,business ,medicine.drug ,Skin preparation - Abstract
The purpose of this study was to determine if 2 paints of chlorhexidine as a skin preparation was as effective as a 5-minute povidone-iodine scrub followed by 2 paints of Betadine solution (Betadine solution, povidone-iodine 10% equal to 1% available iodine; Purdue Frederick, Norwalk, Connecticut). In the first trial involving 10 volunteers, one side of the back was painted with 2 coats of chlorhexidine and the other side of the back was scrubbed with povidone-iodine for 5 minutes, left to dry, and then painted with Betadine. Cultures were obtained using the membrane filter adsorption method before the skin preparation and at 30, 60, and 120 minutes after the preparation. In the second trial, both the Betadine and chlorhexidine paints were dried. Bacterial counts were then obtained at 48 hours. There was no difference between the number of colonies cultured from the povidone-iodine/Betadine compared with the chlorhexidine skin preparation. This finding suggests that chlorhexidine is as effective as 5 minutes of povidone-iodine scrub with 2 paints of povidone-iodine solution.
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- 1999
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16. Povidone-iodine (Betadine) solution: a simple protectant in surgical gloves
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George D S Turner
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medicine.medical_specialty ,business.industry ,chemistry.chemical_element ,Betadine Solution ,General Medicine ,Bacterial Infections ,Surgical Gloves ,Iodine ,Perioperative Care ,Surgery ,chemistry ,Virus Diseases ,Anti-Infective Agents, Local ,Medicine ,Humans ,Gloves, Surgical ,business ,Needlestick Injuries ,Povidone-Iodine - Published
- 2008
17. Botox Therapy for Hyperhydrosis: How I Do It
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Charles B. Slonim
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medicine.medical_specialty ,White powder ,business.industry ,Hyperhidrosis ,Thin layer ,Betadine Solution ,Bleed ,Topical anesthetic ,Surgery ,Grid pattern ,Injection site ,Medicine ,medicine.symptom ,business - Abstract
Hyperhidrosis is the poor man’s detection method for determining where to inject botox: 1. Paint the area (e.g., axilla) with betadine solution (a betadine wipe will do) 2. Allow the betadine to dry 3. Apply a thin layer of cornstarch or fine talc powder over the betadine 4. Shine a handheld spotlight with a 100 W bulb directly on the area 5. The areas of hyperhidrosis will be stimulated and the moisture will cause the betadine to “bleed” through the white powder or cornstarch 6. Photograph the area for documentation 7. Apply a layer of a topical anesthetic (e.g., betacaine, EMLA, etc.) 8. Inject Botox into the dermis in a grid pattern in the targeted area with approximately 1 cm between injections 9. Use 2.5 units in 0.05 cc per injection site
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- 2008
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18. Isolated myocardial hydatid cyst: Managed with total curative excision
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Mohammed Asif, Shalini Garg, Santosh Kumar Sinha, and D. Khanra
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lcsh:Diseases of the circulatory (Cardiovascular) system ,Orthopnea ,medicine.medical_specialty ,left ventricle ,lcsh:Surgery ,lcsh:Medicine ,Betadine Solution ,Hydatid cyst ,Albendazole ,Cystic lesion ,parasitic diseases ,echocardiography ,Medicine ,Ventricular outflow tract ,Cyst ,hydatid cyst ,Cardiac imaging ,business.industry ,lcsh:R ,lcsh:RD1-811 ,Computerized tomography ,medicine.disease ,Surgery ,lcsh:RC666-701 ,medicine.symptom ,business ,medicine.drug - Abstract
Hydatid disease is still prevalent in developing countries, and isolated cardiac hydatid cysts are the rarest presentation. We report a 40-year-old nondiabetic, nonhypertensive female who presented with low-grade fever for 2 months shortness of breath and orthopnea for 2 weeks. Transthoracic echocardiography revealed a large, round cystic lesion with multiple daughter cysts without any obvious intraluminal detached membranes with mass effect on the left ventricular outflow tract. After total excision, residual tissue was closed with Teflon patch. Germinative membrane and hundreds of daughter cysts were seen. Following total excision of the cyst from myocardium, myocardial cavity was washed thoroughly with 10% Betadine solution. Pathological examination confirmed the diagnosis of hydatid cyst. Preoperatively started albendazole was continued for 4 weeks even after the operation. On follow-up after 4 weeks, the patient is doing well and cardiac imaging showed normal contours of the heart.
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- 2016
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19. Effects of Water-Hardening Eggs in a Betadine or Erythromycin Solution on Hatching Success, Development, and Genetic Characteristics of Rainbow Trout
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James E. Peterson and Robb F. Leary
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Antiinfective agent ,Hatching ,Ecology ,Erythromycin ,Betadine Solution ,Aquatic animal ,Biology ,Animal science ,medicine ,%22">Fish ,Rainbow trout ,General Agricultural and Biological Sciences ,Meristics ,medicine.drug - Abstract
We investigated genetic and developmental effects of using a Betadine (povidone–iodine) or erythromycin solution to water-harden eggs from rainbow trout (Oncorhynchus mykiss). Electrophoretic data indicated that no genetic differences existed between control fish and fish from erythromycin-treated eggs. In contrast, a small genetic difference existed between control fish and those from Betadine-treated eggs. The mean counts of five bilateral meristic characters were similar between fish from control and treatment groups, indirectly suggesting that the treatments did not influence development rate. Reduced hatching success was observed from eggs hardened in Betadine solution. Erythromycin appears to have disrupted the development of the fish, as indicated by the increased asymmetry (differences in left- and right-side counts) exhibited by meristic characters. These deleterious effects of the treatments, however, were not large, and in most situations the effects will be far outweighed by the value...
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- 1990
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20. HS07�COMPARISON OF BETADINE PAINT AND PLASTIC BAG IMMERSION TECHNIQUES FOR SURGICAL SITE SKIN PREPARATION IN HAND SURGERY
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R. S. Dhillon, A. Choudhary, and J. Chou
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Alternative methods ,medicine.medical_specialty ,business.industry ,Betadine Solution ,Hand surgery ,General Medicine ,Standard technique ,Surgery ,Surgical site ,Immersion (virtual reality) ,Medicine ,business ,Skin preparation ,Plastic bag - Abstract
Introduction: The aim of this study was to compare two techniques for surgical site skin preparation in hand surgery. Methods: We compared the standard sponge paint technique versus a plastic bag immersion technique using a 10% povidone iodine with alcohol solution (Betadine) to prepare surgical site skin for hand surgery. This plastic bag immersion technique involves using a sterile plastic bag filled with 60 ml of Betadine solution to immerse the subjects’ hand. Samples were taken from ten subjects for bacteria colony forming unit (CFU) counts before and three minutes after surgical site preparation in each group. Outcome measures were preparation time and CFU reduction with a finger impression test using commercially available agar slides. Results: The plastic bag immersion technique significantly reduced (p < 0.0001) the time required for surgical site skin preparation (28 seconds) compared to the standard technique (86 seconds). Both techniques were found to have similar efficacy in the reduction of CFU. Discussion: The plastic bag immersion technique is a quicker alternative method for surgical site preparation in hand surgery and has comparable efficacy to the widely practiced standard paint-on technique. This technique can be applied across the disciplines of orthopaedic, plastic and vascular surgery involving the hand.
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- 2009
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21. Chronic In Vivo Microcirculatory and Hemodynamic Techniques
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Phillip M. Hutchins, Colleen D. Lynch, and Janie Maultsby
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Pharmacological interventions ,In Vitro Techniques ,Angiogenesis ,In vivo ,business.industry ,Human medicine ,Betadine Solution ,Hemodynamics ,Medicine ,business ,Neuroscience ,Chick chorioallantoic membrane - Abstract
This chapter will present the advantages and disadvantages of chronic in vivo preparations and describe the state of the art for some of these preparations. Investigations employing chronic in vivo techniques offer many advantages. For example, tumor necrosis factor alpha (TNFα) has been shown to inhibit the proliferation of endothelial cells in vitro, and to stimulate angiogenesis in vivo.1 The investigation of the interaction of all physiological systems is not possible with in vitro techniques. On the other hand, it is difficult to isolate individual systems and study precise mechanisms of action in vivo. Extrapolation of results acquired from in vivo studies to human medicine is also more appropriate. Knowing the in vivo effects of pharmacological interventions or physiological disturbances on undisturbed microvascular beds is a definite benefit to the interpretation of the true effect of the agent. Ideally, we need to know the response of all vascular beds to a particular perturbation. However, windows into the internal vascular beds (such as refinement of these techniques. Rapid progress is being made in telemetry methods for continuous monitoring of hemodynamic variables. Advancements in this area will also spill over into the telemetering of microvascular images.
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- 1991
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22. In Response The Use of Betadine Solution
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Janet S. Welch
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Betadine Solution ,General Nursing - Published
- 1995
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23. The treatment of experimental peritonitis with intraperitoneal betadine solution
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Craig S. Brown, James M. Blackwood, Jeffrey E. Lavigne, Benjamin F. Rush, and George W. Machiedo
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medicine.drug_class ,Peritonitis ,Betadine Solution ,Tissue Adhesions ,Thyroid Function Tests ,Absorption ,Antiseptic ,Kanamycin ,Cephalothin ,medicine ,Animals ,Povidone-Iodine ,Chronic toxicity ,Escherichia coli Infections ,Experimental peritonitis ,business.industry ,Povidone ,medicine.disease ,Antimicrobial ,Rats ,Disease Models, Animal ,Anesthesia ,Surgery ,business ,Injections, Intraperitoneal ,Iodine ,medicine.drug - Abstract
Betadine (polyvinylpyrrolidone-iodine) antiseptic solution was evaluated as to safety and efficacy on intraperitoneal application in 220 rat experiments, and compared with cephalothin and kanamycin solutions as intraperitoneal antimicrobial agents. We found that intraperitoneal Betadine solution is apparently safe to rats at doses of 2.5 ml/kg or less as regards acute and chronic toxicity. In experimental peritonitis, intraperitoneal Betadine solution produced significantly increased survival (P < 0.0001) over untreated controls, and was as effective as intraperitoneal cephalothin or kanamycin in a monomicrobial peritonitis. Intraperitoneal Betadine solution is well absorbed. Our results suggest that further studies of this application of Betadine solution are indicated.
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- 1974
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24. Outbreak of Serratia Marcescens Associated with the Flexible Fiberbronchoscope
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Arthur Vall-Spinosa and Sidney F. Webb
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,biology ,business.industry ,Outbreak ,Betadine Solution ,Sterilization (microbiology) ,Critical Care and Intensive Care Medicine ,biology.organism_classification ,Surgery ,Bronchoscopies ,Intensive care ,Serratia marcescens ,medicine ,Aseptic processing ,Heavy growth ,Cardiology and Cardiovascular Medicine ,business - Abstract
An outbreak of pulmonary infection due to Serratia marcescens was traced to the use of the flexible fiberbronchoscope. Three patients in two different intensive care units were infected after therapeutic bronchoscopies with a fiberbronchoscope which had been used on a patient identified as having a pulmonary infection from Serratia marcescens . Fluid aspirated through the biopsy channel of the fiberbronchoscope subsequently yielded a heavy growth of the same organism. Cleaning the bronchoscope with 70 percent alcohol and periodic ethylene oxide gas sterilization was found to be inadequate and a sterilization procedure utilizing povidine iodine (Betadine solution) subsequently rendered the bronchoscope aseptic.
- Published
- 1975
- Full Text
- View/download PDF
25. Topical Application of Povidone-Iodine in the Management of Decubitus and Stasis Ulcers
- Author
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Frieda S. Trainor, Bok Y. Lee, and William R. Thoden
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Adult ,Male ,medicine.medical_specialty ,Erythema ,Administration, Topical ,Betadine Solution ,Signs and symptoms ,Edema ,Skin Ulcer ,medicine ,Humans ,Povidone-Iodine ,Ulcer care ,Aged ,Pressure Ulcer ,Wound Healing ,business.industry ,Povidone ,Middle Aged ,Skin ulcer ,Symptomatic relief ,Surgery ,Regimen ,Anesthesia ,Drug Evaluation ,Geriatrics and Gerontology ,medicine.symptom ,business - Abstract
The efficacy of topical applications of povidone-iodine (Betadine solution and ointment) for the control of infection associated with decubitus and stasis ulcers was evaluated in 18 male outpatients (age range, 33--68 years). Dressings were changed twice daily over a period of 42 days. Statistically significant improvement was noted in the following signs and symptoms: edema, pain, erythema, ulcer size, and ulcer depth. All patients experienced some degree of symptomatic relief and clinical improvement within two weeks after starting therapy. At the end of the study, 67 percent of the ulcers were clinically cured and 33 percent showed improvement. Acceptance by the patients was excellent, with no reported side effects or sensitization reactions. Povidone-iodine used in a daily regimen of ulcer care can reduce the level of infection and promote healing.
- Published
- 1979
- Full Text
- View/download PDF
26. Prevention of bacterial growth and local infection in burn wounds
- Author
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George W. Dorman, David S. Trump, Laurence M. Linkner, and Daniel T. Cloud
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,medicine.drug_class ,Betadine Solution ,Betadine Aerosol Spray ,Occlusive Dressings ,Local infection ,Antiseptic ,Methods ,Humans ,Medicine ,Purdue Frederick ,Child ,Intensive care medicine ,Povidone-Iodine ,Retrospective Studies ,Bacteriological Techniques ,Sulfonamides ,business.industry ,Nitrofurazone ,Infant ,Neomycin ,Retrospective cohort study ,Bacterial Infections ,General Medicine ,Clinical judgment ,Occlusive dressing ,Evaluation Studies as Topic ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Anti-Infective Agents, Local ,Wound Infection ,Silver Nitrate ,Female ,Surgery ,Burns ,business - Abstract
Infection has been described as "the cardinal problem in the treatment of burns… [causing] conversion of 2° burns to 3° burns," 1 and as creating the "greatest threat to survival." 2 Fatal septicemia resulting from local infection can best be avoided by preventing development of the infection. Because of the avascular condition of the wound, control of infection generally requires topical antiseptic treatment. 3 In our pediatric surgical practice we have treated many burn patients and have used a variety of topical antiseptics with both the open and closed techniques, prior to developing a routine procedure acceptable to the two general hospitals in the area. On the basis of experience and clinical judgment, we now prefer povidone-iodine (Betadine Solution and Betadine Aerosol Spray) ∗ ∗Betadine Solution contains 10% povidone-iodine (yielding 1% available iodine) and Betadine Aerosol Spray contains 5% pocidone-iodine (yielding 0.5% available iodine), The Purdue Frederick Co., Yonkers, N.Y. with an open technique for the prevention of local infection. This paper examines a decade of accumulated data in an effort to evaluate objectively the validity of our clinical judgment.
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- 1972
- Full Text
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27. Evaluation of two antiseptic agents in surgical preparation of hands by a new method
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Wayne J. Selting, Arthur Gross, Surindar N. Bhaskar, and Duane E. Cutright
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medicine.medical_specialty ,Time Factors ,medicine.drug_class ,Hexachlorophene ,Betadine Solution ,Bacterial counts ,Fingers ,Antiseptic ,Methods ,Humans ,Medicine ,Surgical preparation ,Povidone-Iodine ,Skin ,Bacteriological Techniques ,Bacteria ,business.industry ,Povidone ,Water jet ,General Medicine ,Hand ,Surgery ,Evaluation Studies as Topic ,Anti-Infective Agents, Local ,business - Abstract
Summary A new method of surgical preparation of hands with pHisoHex and Betadine Solution was evaluated in thirteen subjects. The results indicate that the pulsating water jet device is effective in surgical preparation of hands. The immediate disinfecting effect of Betadine Solution is greater than that of pHisoHex. Two hours post scrub, however, no significant differences in bacterial counts on hands treated with the two preparations are evident.
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- 1973
- Full Text
- View/download PDF
28. Wound sterilization: CO2 laser versus iodine
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M.B. Jarmuske, M.M. Al-Qattan, M.F. Stranc, and D.J. Hoban
- Subjects
Adult ,Male ,medicine.medical_specialty ,chemistry.chemical_element ,Betadine Solution ,Iodine ,Bacterial counts ,Medicine ,Animals ,Humans ,Surgical Wound Infection ,Pseudomonas Infections ,Aged ,Co2 laser ,integumentary system ,business.industry ,Sterilization ,Surgical wound ,Sterilization (microbiology) ,Carbon Dioxide ,Middle Aged ,Infected wound ,Surgery ,Panniculus carnosus ,Otorhinolaryngology ,chemistry ,Laser Therapy ,Rabbits ,business - Abstract
Control of infection in a surgical wound remains a challenge, especially if further surgery in the area is needed. This study was designed to compare the effectiveness of sterilization of a standard experimental infected wound by surgical skin preparation (Betadine) as compared to treatment with the CO2 laser. Standard wounds (5 x 6 cm) were created superficial to the panniculus carnosus on each flank of 37 adult male New Zealand rabbits. Each wound was infected with a standard dose of Pseudomonas aeruginosa. All wounds became grossly infected. On the third day one flank wound was treated with the CO2 laser, the other with the Betadine solution, and a punch biopsy (4 mm) was taken from each wound for quantitative bacterial counts. Less than 10% of the laser-treated wounds grew Pseudomonas, whereas nearly 40% of the iodine-treated wounds remained infected (P less than 0.005). Our early clinical experience using the CO2 laser for the sterilization of infected wounds is also reported.
- Published
- 1989
29. Inactivation of HIV by Povidone-iodine
- Author
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Paul D. Goldenheim
- Subjects
medicine.medical_specialty ,business.industry ,Human immunodeficiency virus (HIV) ,HIV ,Povidone ,Betadine Solution ,Microbial Sensitivity Tests ,General Medicine ,Betadine Surgical Scrub ,medicine.disease_cause ,Dermatology ,Virology ,Virus type ,Infectious disease (medical specialty) ,medicine ,In vitro study ,General hospital ,business ,Povidone-Iodine ,Infection Control Practitioners - Abstract
To the Editor.— In a Letter to the Editor, Schuster et al 1 suggested that iodophors such as povidone-iodine (Betadine) can "reasonably" be expected to inactivate human immunodeficiency virus (HIV), also known as human T-cell lymphotrophic virus type III. The authors urged that compounds such as iodophors, which are "used almost universally for personal and patient disinfection," be evaluated for eradication of HIV before turning attention to ionizing radiation and other agents. In response to Schuster and colleagues as well as to many other infection control practitioners who have shown a continuing and extensive interest in this topic, we supported an in vitro study that evaluated the use of Betadine solution (10% povidone-iodine) and Betadine surgical scrub (7.5% povidone-iodine) in the inactivation of HIV. The study was conducted in the Infectious Disease Unit of Massachusetts General Hospital, Boston, by Robert T. Schooley, MD, and associates and was recently completed. (The
- Published
- 1987
- Full Text
- View/download PDF
30. BETADINE® Solution, BETADINE® Skin Cleanser, BETADINE® Surgical Scrub, and BETASEPTIC® demonstrated excellent virucidal in-vitro efficacy against Ebola virus Zaire and Modified vaccinia virus Ankara
- Author
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Maren Eggers, Markus Eickmann, and Juergen Zorn
- Subjects
Microbiology (medical) ,General Immunology and Microbiology ,business.industry ,Betadine Solution ,General Medicine ,Betadine Surgical Scrub ,Ebola virus Zaire ,Virology ,Virus ,Skin cleanser ,chemistry.chemical_compound ,Infectious Diseases ,chemistry ,Immunology and Microbiology(all) ,Immunology and Allergy ,Medicine ,Vaccinia ,business - Full Text
- View/download PDF
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