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168 results on '"Bi, Hong Sheng"'

13. Synaptosomal Actin Dynamics in the Developmental Visual Cortex Regulate Behavioral Visual Acuity in Rats

Author

Bi, Ai-Ling, primary, Zhang, Yue-Ying, additional, Lu, Zhi-Yuan, additional, Tang, Hong-Ying, additional, Zhang, Xiu-Yan, additional, Zhang, Zi-Han, additional, Li, Bo-Qin, additional, Guo, Da-Dong, additional, Gong, Sheng, additional, Li, Qian, additional, Wang, Xing-Rong, additional, Lu, Xiu-Zhen, additional, and Bi, Hong-Sheng, additional

Published
2021
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19. Differences in ocular biometry between urban and rural children matched by refractive error: the Shandong Children Eye Study

Author

Rozema, Jos J, primary, Sun, Wei, additional, Wu, Jian Feng, additional, Jiang, Wen Jun, additional, Wu, Hui, additional, Lu, Tai Liang, additional, Hu, Yuan Yuan, additional, Chen, Rong, additional, Guo, Da Dong, additional, Wang, Xing Rong, additional, Dankert, Sebastian, additional, Jonas, Jost B, additional, Iribarren, Rafael, additional, Tian, Qing Mei, additional, and Bi, Hong Sheng, additional

Published
2019
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24. Education-Related Parameters in High Myopia: Adults versus School Children

Author

Jonas, Jost B., Xu, Liang, Wang, Ya Xing, Bi, Hong Sheng, Wu, Jian Feng, Jiang, Wen Jun, Nangia, Vinay, Sinha, Ajit, Zhu, Dan, Tao, Yong, Guo, Yin, You, Qi Sheng, Wu, Li Juan, Tao, Li Xin, Guo, Xiu Hua, Ohno-Matsui, Kyoko, and Panda-Jonas, Songhomitra

Subjects
Adult, Asia, genetic structures, Adolescent, lcsh:Medicine, Social Sciences, India, Pediatrics, Ecosystems, Education, Geographical Locations, Families, Sociology, Medicine and Health Sciences, Myopia, Genetics, Humans, lcsh:Science, Child, Children, Visual Impairments, Schools, Deserts, Ecology, lcsh:R, Ecology and Environmental Sciences, Biology and Life Sciences, Human Genetics, Middle Aged, Terrestrial Environments, eye diseases, Ophthalmology, Age Groups, Child, Preschool, People and Places, lcsh:Q, Population Groupings, sense organs, Research Article
Abstract

PURPOSE:Since high myopia in the younger generation may differ etiologically from high myopia in older generations, we examined whether education-related parameters differ between high myopia in today´s school children and high pathological myopia in today´s elderly generation. METHODS:The investigation included the adult populations of the population-based Beijing Eye Study (BES) (3468 adults;mean age:64.6±9.8years;range:50-93years) and Central India Eye and Medical Study (CIEMS) (4711 adults;age:49.±13.2years;range:30-100years), and the children and teenager populations of the Shandong Children Eye Study (SCES) (6026 children;age:9.7±3.3years;range:4-18years;cycloplegic refractometry), Gobi Desert Children Eye Study (1565;age:11.9±3.5years;range:6-21 years;cycloplegic refractometry), Beijing Pediatric Eye Study (681 children;age:7.7±1.6years;range:5-13 years;non-cycloplegic refractometry,calculation of axial length to corneal curvature radius ratio), Beijing Children Eye Study (15066 children;age:13.2±3.4years;range:7-18years;non-cycloplegic refractometry), Beijing High School Teenager Eye Study (4677 children;age:16.9±0.7years;range:16-18years;non-cycloplegic refractometry). RESULTS:In the BES and CIEMS, educational level did not differ significantly between, or was significantly lower in the highly myopic group (myopic refractive error ≥6 diopters) than in the non-highly myopic group. In all non-adult study populations, higher prevalence of high myopia was significantly associated with higher degree of education related parameters such as attendance of high-level schools, and more time spent for indoors near work versus time spent outdoors. CONCLUSIONS:Comparing associations of old or genetic high myopia in adults with new or acquired high myopia in school children revealed that education-related parameters did not show a clear association with old or genetic high myopia, while in contrast, new high myopia showed strong associations with education. It confirms previous studies that the two forms of high myopia not only differed in age of onset, but also in associations with education as well. The data support the notion of two types of high myopia. Future studies may assess whether the risk of pathologic myopic maculopathy and high myopia associated open-angle glaucoma differs between both types of high myopia.

Published
2016

28. Corneal Curvature Radius in Myopia of Schoolchildren Versus Adult Myopia

Author

Jonas, Jost B., primary, Bi, Hong Sheng, additional, Wu, Jian Feng, additional, Xu, Liang, additional, Wang, Ya Xing, additional, Wei, Wen Bin, additional, Nangia, Vinay, additional, Sinha, Ajit, additional, Guo, Yin, additional, You, Qi Sheng, additional, Ohno-Matsui, Kyoko, additional, and Panda-Jonas, Songhomitra, additional

Published
2016
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33. Prevalence and Associations of Anisometropia in Children

Author

Hu, Yuan Yuan, primary, Wu, Jian Feng, additional, Lu, Tai Liang, additional, Wu, Hui, additional, Sun, Wei, additional, Guo, Da Dong, additional, Jiang, Wen Jun, additional, Wang, Xing Rong, additional, Jonas, Jost B., additional, and Bi, Hong Sheng, additional

Published
2016
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35. Macular Choroidal Thickness in Children: The Shandong Children Eye Study

Author

Zhang, Juan Mei, primary, Wu, Jian Feng, additional, Chen, Jian Hua, additional, Wang, Ling, additional, Lu, Tai Liang, additional, Sun, Wei, additional, Hu, Yuan Yuan, additional, Jiang, Wen Jun, additional, Guo, Da Dong, additional, Wang, Xing Rong, additional, Bi, Hong Sheng, additional, and Jonas, Jost B., additional

Published
2015
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49. Early changes in corneal densitometry after FS-LASIK combined with accelerated corneal cross-linking for correction of high myopia.

Author

Wang QB, Bi HS, Wang XF, Fan H, Li L, and Ji P

Abstract

Aim: To observe the effects of femtosecond laser-assisted excimer laser in situ keratomileusis combined with accelerated corneal cross-linking (FS-LASIK Xtra) on corneal densitometry after correcting for high myopia., Methods: In this prospectively study, 130 patients underwent FS-LASIK or FS-LASIK Xtra for high myopia. Their right eyes were selected for inclusion in the study, of which 65 cases of 65 eyes in the FS-LASIK group, 65 patients with 65 eyes in the FS-LASIK Xtra group. Patients were evaluated for corneal densitometry at 1, 3, and 6mo postoperatively using Pentacam Scheimpflug imaging., Results: Preoperative differences in corneal densitometry between the FS-LASIK and FS-LASIK Xtra groups in different ranges were not statistically significant ( P >0.05). Layer-by-layer analysis revealed statistically significant differences in the anterior (120 µm), central, and total layer corneal densitometry between the FS-LASIK and FS-LASIK Xtra groups at 1 and 3mo postoperatively (all P <0.05), the FS-LASIK Xtra group is higher than that of the FS-LASIK group. Analysis of different diameter ranges showed statistically significant differences between the FS-LASIK group and the FS-LASIK Xtra group at 1mo postoperatively in the ranges of 0-2, 2-6, and 6-10 mm (both P <0.05); At 3mo postoperatively, the FS-LASIK Xtra group is higher than that of the FS-LASIK group in the ranges of 0-2 and 2-6 mm ( P <0.05). At 6mo postoperatively, there were no statistically significant differences in corneal densitometry between the FS-LASIK group and the FS-LASIK Xtra group in different diameter ranges (all P >0.05)., Conclusion: There is an increase in internal corneal densitometry during the early postoperative period after FS-LASIK Xtra for correction of high myopia. However, the densitometry values decreased to the level of conventional FS-LASIK at 6mo after surgery, with the most significant changes observed in the superficial central zone., Competing Interests: Conflicts of Interest: Wang QB, None; Bi HS, None; Wang XF, None; Fan H, None; Li L, None; Ji P, None., (International Journal of Ophthalmology Press.)

Published
2024
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50. Electroacupuncture alleviates ciliary muscle cell apoptosis in lens-induced myopic guinea pigs through inhibiting the mitochondrial signaling pathway.

Author

Yang ZH, Hao JW, Liu JP, Bao B, Li TL, Wu QX, He MG, Bi HS, and Guo DD

Abstract

Aim: To investigate the effect of electroacupuncture (EA) on the mitochondria-dependent apoptotic signaling pathway in the ciliary muscle of guinea pigs with negative lens-induced myopia (LIM)., Methods: Guinea pigs were randomly divided into normal control (NC) group, LIM group, LIM+SHAM acupoint (LIM+SHAM) group, and LIM+EA group. Animals in the NC group received no intervention, while those in other three groups were covered with -6.0 diopter (D) lenses on right eyes. Meanwhile, animals in the LIM+EA group received EA at Hegu (LI4) combined with Taiyang (EX-HN5) acupoints, while those in the LIM+SHAM group were treated at sham points. After treatments for 1, 2, and 4wk, morphological changes in ciliary muscles were observed with hematoxylin and eosin (H&E) staining and nick end labeling (TUNEL), and the expression of the mitochondrial apoptotic signaling pathway-related molecules in ciliary muscles was measured by real-time quantitative polymerase chain reaction (qPCR) and Western blot. Additionally, the adenosine triphosphate (ATP) contents were also determined in ciliary muscles., Results: Axial length increased significantly in the LIM and LIM+SHAM groups and decreased in the LIM+EA group. The ciliary muscle fibers were broken and destroyed in both LIM and LIM+SHAM groups, whereas those in the LIM+EA group improved significantly. TUNEL assay showed the number of apoptotic cells increased in the LIM and LIM+SHAM groups, whereas reduced in the LIM+EA group. ATP contents showed a significant decrease in the LIM and LIM+SHAM groups, whereas increased after EA treatment. Compared with the NC group, the dynamin-related protein 1 (DRP1), Caspase3, and apoptotic protease activator 1 (APAF1) levels were significantly increased in the LIM group and decreased in the LIM+EA group., Conclusion: The results provide evidence of EA inhibiting the development of myopia by regulating the mitochondrial apoptotic signaling pathway., (International Journal of Ophthalmology Press.)

Published
2023
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