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Rapid detection of bacterial pathogens and toxic contaminants in the environment is essential for providing real-time results to mitigate potential safety hazards. This study prepared a wearable fabric sensing material based on fluorescent nanomaterials. The nano silver/europium complex is assembled layer by layer with sodium alginate to obtain nanoparticle aggregates with strong fluorescence, and then these are covalently bonded onto the cotton fabric surface to obtain the fluorescence cotton fabric (FCF). Via fluorescence quenching, FCF can sensitively sense Escherichia coli and Staphylococcus aureus and show good antibacterial activity. Besides, the selected transition metal ions can be detected qualitatively through the functional relationship between the fluorescence intensity and metal ion dose. The viability test of NIH3T3 cells showed that FCF had good biocompatibility. This fluorescent fabric sensing material has the characteristics of being wearable, antibacterial, and biocompatible. It realizes the real-time detection of bacteria and toxic metal ions and has great application prospects in environmental and biological monitoring. [ABSTRACT FROM AUTHOR]

The clinical use of anticancer drugs necessitates new technologies for their safe, sensitive, and selective detection. In this article, lanthanide (Eu3+ and Tb3+)-loaded γ-cyclodextrin nano-aggregates (ECA and TCA) are reported, which sensitively detects the anticancer drug irinotecan by fluorescence intensity changes. Fluorescent lanthanide (Eu3+ and Tb3+) complexes exhibit high fluorescence intensity, narrow and distinct emission bands, long fluorescence lifetime, and insensitivity to photobleaching. However, these lanthanide (Eu3+ and Tb3+) complexes are essentially hydrophobic, toxic, and non-biocompatible. Lanthanide (Eu3+ and Tb3+) complexes were loaded into naturally hydrophilic γ-cyclodextrin to form fluorescent nano-aggregates. The biological nontoxicity and cytocompatibility of ECA and TCA fluorescent nanoparticles were demonstrated by cytotoxicity experiments. The ECA and TCA fluorescence nanosensors can detect irinotecan selectively and sensitively through the change of fluorescence intensity, with detection limits of 6.80 μM and 2.89 μM, respectively. ECA can safely detect irinotecan in the cellular environment, while TCA can detect irinotecan intracellularly and is suitable for cell labeling. [ABSTRACT FROM AUTHOR]