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1. Acute Delta Hepatitis in Italy spanning three decades (1991-2019): Evidence for the effectiveness of the hepatitis B vaccination campaign

Author

Tommaso, Stroffolini, Filomena, Morisco, Luigina, Ferrigno, Giuseppina, Pontillo, Giuseppina, Iantosca, Valentina, Cossiga, Simonetta, Crateri, Maria Elena Tosti, Valeria, Alfonsi, Franca, D'Angelo, Zotti, Carla Maria, Rainero, Erika, Marengo, Noemi, Silvana, Malaspina, Angela, Gallone, Annalisa, Castella, Maria Teresa Galati, Annamaria, Scala, Paolo, Castagna, Virginia, Silano, Sebastiano, D'Agosta, Maria Grazia Tacca, Silvia, Iodice, Vilma, Corvi, Maurizio, Oddone, Daniela, Rivetti, Paola, Ravaschietto, Franco, Giovanetti, Teresa, Cappello, Alessandro, Smaniotto, Mario, Ruffier, Marina, Verardo, Maria, Gramegna, Sabrina, Senatore, Danilo, Cereda, Annalisa, Donadini, Carla, Nespoli, Livia, Trezzi, Giorgio, Gennati, Angelo, Monteverdi, Liana, Boldori, Franco Paolo Tortorella, Paola Elvira Merlini, Davide Di Caterina, Marino, Faccini, Anna, Lamberti, Eva, Rossetti, Rita, Brugnoli, Giulia, Mainardi, Alessandra, Vezzoli, Daniela, Caso, Milena, Testa, Alice, Erba, Paola, Senegaglia, Annamaria, Spagna, Silvia, Lodola, Marcello, Tirani, Enza, Giompapa, Luigi Guido Roveri, Gabriele, Guardigli, Vanna, Scalvinoni, Silvia, Spertini, Sabine, Gamper, Andrea, Grünfelder, Barbara, Ploner, Verena, Runggatscher, Silvia, Molinaro, Maria Grazia Zuccali, Silvia, Franchini, Francesca, Russo, Francesca, Zanella, Donatella, Rizzato, Graziella, Carpene, Nadia, Lamonato, Emanuela, Destefani, Alessandra Dal Zotto, Rita Dal Zotto, Paola, Casagrande, Felice, Foglia, Gemma, Zorzi, Ester, Chermaz, Liana, Gava, Luigi, Nicolardi, Lorena, Pavanetto, Cecilia, Battiston, Francesco De Grandi, Laura, Rizzato, Michele, Tonon, Elisabetta, Cannizzo, Maurizio, Foroni, Laura, Colucci, Monica, Barbieri, Rosanna, Ledri, Tolinda, Gallo, Giulio, Rocco, Rossana, Stacul, Ariella, Breda, Andrea, Iob, Simonetta, Micossi, Oriana, Feltrin, Giuseppina, Caernelos, Marco, Mela, Virna, Frumento, Anna, Opisso, Alessandro, Cuccu, Giorgio, Zoppi, Patrizia, Torracca, Armanda, Capellini, Francesco, Maddalo, Giovanna, Mattei, Claudio, Gualanduzzi, Erika, Massimiliani, Anna Rita Sacchi, Laura, Gardenghi, Anna Rosa Gianninoni, Elena Dalle Donne, Roberto, Rangoni, Annalisa, Califano, Chiara, Reali, Emilia, Biguzzi, Barbara, Bondi, Anna, Pecci, Bianca Maria Borrini, Lucia, Pecori, Emanuela, Balocchini, Costanza, Pierozzi, Rosa, Luzzoli, Paola, Marchini, Lara, Lucchesi, Alberto, Tomasi, Elisabetta, Raso, Nadia, Olimpi, Cristiana, Berti, Francesca, Matarazzo, Nicoletta, Galletti, Laura, Puppa, Marinella, Frasca, Alessandro, Barbieri, Chiara, Cinughi, Maria, Bandini, Iorio, Lezzi, Fabrizia, Verdelli, Renzo, Paradisi, Rita, Bindi, Cinzia Monica Sansone, Maria, Rosati, Federica, Zacchini, Simonetta, Baretti, Rossella, Cecconi, Chiara, Staderini, Poalo, Filidei, Elisabetta, Alfaroli, Franco, Barghini, Marina, Cadoni, Anna, Tosti, Giovannini, G, Giovanni, Piattellini, Alessandra, Buscosi, Anna, Pasquale, Carla, Ciani, Maria Claudia Paoloni, Franco, Santocchia, Maria Laura Proietti, Daniel, Fiacchini, Dzenana, Hazurovic, Maria Sole Giamprini, Katia, Gatti, Jacqueline Van Will, Alfredo, Vaccaro, Maria Margherita Sbarbati, Alessandra, Amelio, Daniela, Cimini, Vania, Moroni, Daniela, Francoletti, Federica, Scaccia, Elisabetta, Branchesi, Selena, Saracino, Catia, Mezzanotte, Susanna, Cimica, Vita, Vitale, Franca, Laici, Irene, Petrelli, Barbara, Airini, Gabriella, Passarini, Lucia, Ruffini, Anna Maria Lambertucci, Annarita, Mogetta, Francesca, Cioccoloni, Giuseppe, Ciarrocchi, Marina, Pistolesi, Erika, Fratello, Francesca, Picciotti, Claudio, Angelini, Paola, Scognamiglio, Francesco, Vairo, Andreina, Ercole, Antonio Salvatore Maglietta, Fabrizio, Magrelli, Fabrizio, Perrelli, Carlo, Cerocchi, Paolo, Grillo, Cristina, Vazzoler, Maria Rosaria Loffredo, Alessio, Pendenza, Maria Rosaria Nappi, Paola, Bueti, Luigi, Santucci, Franca, Mangiagli, Donatella, Varrenti, Silvia, Aquilani, Pietro, Dionette, Daniela, Corpolongo, Giuseppe Di Luzio, Manuela Di Giacomo, Enrico, Giansanti, Cristiana, Mancini, Claudio, Turchi, Carla, Granchelli, Graziella, Soldato, Felesina, D'Eugenio, Ida, Albanesi, Maria Antonietta Ferrara, Annarita, Citarella, Elena, Fossi, Rosa, Alfieri, Milena, Scotto, Anna Luisa Caiazzo, Rosa, Prato, Maria, Chironna, Domenico, Martinelli, Francesca, Fortunato, Maria Giovanna Cappelli, Daniela, Loconsole, Anna, Morea, Giulia Del Matto, Raffaele, Angelillis, Marcello, Antonazzo, Valerio, Aprile, Grazia Maria Avella, Roberta, Cambria, Giovanni, Caputi, Rosati, Cipriani, Carlo De Santis, Francesco, Desiante, Marisa, Ferraro, Vera, Laforgia, Antonino, Madaro, Maria Giuseppina Maluccio, Anna Maria Matera, Stefania, Menolascina, Giuseppina, Moffa, Maria, Nesta, Rita, Olivieri, Onofrio, Pagone, Pasquale, Pedote, Rosella, Squicciarini, Stefano, Termite, Viviana, Vitale, Francesco, Negrone, Manuela, Maldini, Giovanni, Laugello, Teresa, Russo, Anna Domenica Mignuoli, Giuseppe, Afflitto, Benedetto, Caroleo, Maria, Montesanti, Vincenzo De Giorgio, Antonio, Maradei, Rocco Cataldo Romeo, Francesca, Scrivano, Elisa, Lazzarino, Vittoria, Surace, Antonella, Giordano, Alessandro, Bisbano, Anita, Arcuri, Ida, Valentini, Rossana, Mangione, Valentina, Meli, Mario, Cuccia, Elena, Longhitano, Fiorenzo, Delogu, Donatella, Fracasso, Maria Vittoria Marceddu, Antonina, Puggioni, Maria Valentina Eugenua Marras, Rita, Serpi, Simonetta, Santus, Valentina, Marras, Stroffolini, Tommaso, Morisco, Filomena, Ferrigno, Luigina, Pontillo, Giuseppina, Iantosca, Giuseppina, Cossiga, Valentina, Crateri, Simonetta, and Tosti, Maria Elena

Subjects
Adult, Male, medicine.medical_specialty, HBsAg, Hepatitis B virus, viruses, Population, hepatitis delta, medicine.disease_cause, Virology, Internal medicine, Epidemiology, medicine, Humans, hepatitis B vaccination, education, Hepatitis, education.field_of_study, Hepatitis B Surface Antigens, Hepatology, business.industry, Immunization Programs, Incidence (epidemiology), virus diseases, biochemical phenomena, metabolism, and nutrition, medicine.disease, Hepatitis B, Hepatitis D, Vaccination, Infectious Diseases, surveillance, epidemiology, Female, Hepatitis Delta Virus, business, Viral hepatitis
Abstract

Updated incidence data of acute Delta virus hepatitis (HDV) are lacking worldwide. Our aim was to evaluate incidence of and risk factors for acute HDV in Italy after the introduction of the compulsory vaccination against hepatitis B virus (HBV) in 1991. Data were obtained from the National Surveillance System of acute viral hepatitis (SEIEVA). Independent predictors of HDV were assessed by logistic-regression analysis. The incidence of acute HDV per 1-million population declined from 3.2 cases in 1987 to 0.04 in 2019, parallel to that of acute HBV per 100,000 from 10.0 to 0.39 cases during the same period. The median age of cases increased from 27 years in the decade 1991-1999 to 44 years in the decade 2010-2019 (p

Published
2021

2. Outbreak of a new measles B3 variant in the Roma/Sinti population with transmission in the nosocomial setting, Italy, November 2015 to April 2016

Author

Antonella Amendola, Sabrina Senatore, Melissa Baggieri, Maria Teresa Filipponi, Antonietta Filia, Martina Del Manso, Giulia Piccirilli, Alessio Ciampelli, Marino Faccini, Bianca Maria Borrini, Maria Grazia Pascucci, Silvia Bianchi, Fabio Magurano, Elisabetta Tanzi, Tiziana Lazzarotto, Filia, A, Amendola, A, Faccini, M, Del Manso, M, Senatore, S, Bianchi, S, Borrini, Bm, Ciampelli, A, Tanzi, E, Filipponi, Mt, Piccirilli, G, Lazzarotto, T, Pascucci, Mg, Baggieri, M, and Magurano, F.

Subjects
0301 basic medicine, Pediatrics, medicine.medical_specialty, Epidemiology, 030106 microbiology, Population, Ethnic group, Measles outbreak, Measles, Measles virus, 03 medical and health sciences, 0302 clinical medicine, healthcare-associated infection, Virology, medicine, measle, 030212 general & internal medicine, education, education.field_of_study, Surveillance, outbreak, biology, Transmission (medicine), business.industry, Public Health, Environmental and Occupational Health, Outbreak, medicine.disease, biology.organism_classification, vaccine-preventable diseases, Vaccine-preventable diseases, business, laboratory surveillance, Demography
Abstract

A measles outbreak occurred from November 2015 to April 2016 in two northern Italian regions, affecting the Roma/Sinti ethnic population and nosocomial setting. Overall, 67 cases were reported. Median age of 43 cases in three Roma/Sinti camps was four years, nosocomial cases were mainly adults. The outbreak was caused by a new measles virus B3.1 variant. Immunisation resources and strategies should be directed at groups with gaps in vaccine coverage, e.g. Roma/Sinti and healthcare workers.

Published
2016
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3. Dry mouth as an initial sign of food-borne botulism: a case report and review of the literature

Author

Giovanni Pavesi, Guido Maria Macaluso, Piero de Giampaulis, Maddalena Manfredi, Bianca Maria Borrini, Monica Angelini, Umberto Scoditti, and Paolo Vescovi

Subjects
Adult, Male, medicine.medical_specialty, Eye Infections, medicine.disease_cause, Xerostomia, Diagnosis, Differential, Food, Preserved, Vegetables, Diseases in Twins, medicine, Humans, Effective treatment, Botulism, General Dentistry, business.industry, Mouth Mucosa, medicine.disease, Dermatology, Surgery, Otorhinolaryngology, Food borne, Clostridium botulinum, Oral Surgery, Deglutition Disorders, Mouth Diseases, business, Identical twins
Abstract

Botulism is a rare neuroparalytic disease caused by a potent neurotoxin produced by Clostridium botulinum. There are different clinical types of botulism. Early diagnosis of the condition is essential for effective treatment. We report a case of food-borne botulism in identical twins characterized by severe initial oral involvement and a review of the literature about the condition.

Published
2011
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4. [Tuberculosis among children and young adults in Emilia-Romagna Region (Northern Italy): surveillance system and integration with socioeconomic data]

Author

Matteo, Morandi, Chiara, Di Girolamo, Nicola, Caranci, Andrea, Mattivi, Massimiliano, Marchi, Bianca Maria, Borrini, and Maria Luisa, Moro

Subjects
Male, Young Adult, Adolescent, Italy, Socioeconomic Factors, Child, Preschool, Population Surveillance, Humans, Tuberculosis, Female, Child
Abstract

to characterise the cases of tuberculosis (TB) aged 0-24 years reported in Emilia-Romagna (Northern Italy) Region between 2001 and 2010 through an ecological approach and from a sociodemographic perspective.observational study on notified TB cases, with data integration and subsequent location through geocoding and ecological deprivation index.notification records of TB cases identified by the current surveillance system. Cases were geocoded where address details were available and, through spatial intersection with census block polygons, the related deprivation index (DI) was attributed to them.deprivation index distribution of the observed cases.in the considered decade, 686 cases of tuberculosis in the age group 0-24 years were reported, 14.5% of the overall number of cases in the Emilia-Romagna Region. The DI was attributed to the 90.4% of cases. Notified TB cases were more frequently located in the most deprived areas.as other TB international surveillance systems, this study shows that it is possible to locate TB cases, to link them with census data and, therefore, to characterise with socioeconomic information. Looking ahead, the extension of the analysis to all age classes, the updating of socioeconomic data and the use of qualitative methodologies can integrate surveillance system data to better describe the social disadvantage among TB cases.

Published
2015

5. Hepatitis A outbreak in Italy, 2013: a matched case–control study

Author

E. Massimiliani, Bianca Maria Borrini, B Natter, M Augschiller, Marina Nadia Losio, Maria Elena Tosti, Rosa Prato, Tolinda Gallo, Stefania Taffon, Valeria Alfonsi, Vanessa Cozza, Maria Chironna, Lara Ricotta, A. Bella, A Foppa, C Gualanduzzi, S Franchini, Roberto Bruni, Anna Rita Ciccaglione, C Montaño-Remacha, Michele Equestre, V Carraro, A C Finarelli, and Caterina Rizzo

Subjects
Veterinary medicine, Epidemiology, business.industry, Incidence (epidemiology), Public Health, Environmental and Occupational Health, Case-control study, Outbreak, Hepatitis A, Retrospective cohort study, Odds ratio, medicine.disease, Confidence interval, Virology, medicine, Risk factor, business
Abstract

Between January and May 2013 a hepatitis A (HA) incidence increase was detected in Italy, signalling an outbreak. A retrospective matched case-control study was conducted to identify the source of infection. A case was defined as a resident of any of five regions (Apulia, autonomous province of Bolzano, Emilia-Romagna, Friuli-Venezia-Giulia and autonomous province of Trento), who had symptom onset between 1 January and 31 May2013 as well a positive test for anti-HA virus IgM. We compared each case with four age-and neighbourhood-matched controls. Overall 119 cases and 419 controls were enrolled. Berries were found as the main risk factor for HA (adjusted odds ratio (ORadj): 4.2; 95% confidence interval (CI): 2.5-7.0) followed by raw seafood (ORadj: 3.8; 95% CI: 2.2-6.8; PAF: 26%). Sequencing the virion protein (VP)1-2a region from 24 cases yielded a common sequence (GenBank number: KF182323). The same sequence was amplified from frozen mixed berries consumed by some cases as well as from isolates from Dutch and German HA patients, who had visited some of the affected Italian provinces during the outbreak. These findings suggested berries as the main source of the Italian outbreak. Control measures included voluntary recall of the confirmed frozen mixed berry batches and a trace-back investigation was initiated. The Ministry of Health website recommends frozen berries to be cooked for two minutes before eating. .

Published
2014
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6. [Untitled]

Author

Caterina Caminiti, Maurizio Impallomeni, Bianca Maria Borrini, and Giuliana Battistini

Subjects
Tuberculina, Pediatrics, medicine.medical_specialty, Randomization, Tuberculosis, biology, medicine.diagnostic_test, Epidemiology, business.industry, Adult population, Tuberculin, Mantoux test, biology.organism_classification, medicine.disease, Surgery, medicine, False positive paradox, business
Abstract

Between February 1993 and December 1994, 875 adults underwent tuberculin screening by the Public Health Service of Parma. The adults were randomly assigned to a multipuncture test, Tine or Mono, and contemporarily, as a reference test, received the intradermal Mantoux (IM) in the opposite arm. The tests were then read 72 hours later by two different trained nurses. The error quota due to IM was estimated by repeating both the tests done initially in patients with discordant results. The Mono test revealed a sensitivity of 95%, which was the same as that observed for the Mantoux test. As an 'operative index' of the screening, the number of false positives subsequently tested for every 10 correctly identified was used. The authors retain that the results obtained indicate the validity of the Mono test for screening in the adult population with a prevalence of tuberculous infection above 10%.

Published
1998
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7. [Diagnostic delay in patients with pulmonary tuberculosis]

Author

Maria Luisa, Moro, Davide, Resi, Francesca, Mezzetti, and Bianca Maria, Borrini

Subjects
Adult, Male, Time Factors, Middle Aged, Diagnosis, Differential, Italy, Risk Factors, Case-Control Studies, Humans, Female, Family Practice, Referral and Consultation, Tuberculosis, Pulmonary, Aged
Abstract

Delay in pulmonary tuberculosis diagnosis prolongs the period of time in which a patient is infectious, promoting tuberculosis transmission. We quantified diagnostic delay and examined delay associated factors in a regional wide case-control study set in Emilia-Romagna. A total 55 days median delay, with no significant difference between native and foreign-born patients, was observed in this study. Longer delay was observed when a general practitioner was consulted as first provider and when clinical picture was not fully manifest. This study points out the need of improving physicians' awareness of tuberculosis disease especially when they care for elderly people and foreign-born patients.

Published
2003

8. Erratum to 'Dry mouth as an initial sign of food-borne botulism: a case report and review of the literature' [Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;111(4):e15-e18]

Author

Guido Maria Macaluso, Bianca Maria Borrini, Maddalena Manfredi, Monica Angelini, Giovanni Pavesi, Paolo Vescovi, Piero de Giampaulis, and Umberto Scoditti

Subjects
business.industry, Dentistry, Dry mouth, medicine.disease, Pathology and Forensic Medicine, Sign (linguistics), Food borne, medicine, Radiology, Nuclear Medicine and imaging, Dentistry (miscellaneous), Surgery, Botulism, Oral Surgery, medicine.symptom, business
Published
2012
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